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Your search keyword '"Mattson, Matthew N."' showing total 14 results

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14 results on '"Mattson, Matthew N."'

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1. Synthesis of chiral pilocarpine analogues via a C-8 ketone intermediate

2. A new method for expeditious ketone synthesis from acids via acyl hemiacetals

4. Design, synthesis and structure–activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent γ-secretase inhibitors

5. Discovery of sulfonamide–pyrazole γ-secretase inhibitors

6. Discovery of (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): Metabolically Stable γ-Secretase Inhibitors that Selectively Inhibit the Production of Amyloid-β over Notch

7. Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease

12. Discoveryof (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and(R)-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline...

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