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13 results on '"Milica Atanacković Krstonošić"'

1. The Potential of Natural Compounds in UV Protection Products

Author

Jovana Milutinov, Nebojša Pavlović, Dejan Ćirin, Milica Atanacković Krstonošić, and Veljko Krstonošić

Subjects
sunscreen, SPF, natural UV filters, flavonoids, Organic chemistry, QD241-441
Abstract

Overexposure to ultraviolet radiation mainly leads to skin disorders (erythema, burns, immunosuppression), skin aging, and skin cancer as the most serious side effect. It has been widely accepted that using sunscreen products is an important way to protect against the harmful effects of UV rays. Although commercial sunscreens have constantly changed and improved over time, there are emerging concerns about the safety of conventional, organic, UV filters due to adverse effects on humans (such as photoallergic dermatitis, contact sensitivity, endocrine-disrupting effects, etc.) as well as accumulation in the environment and aquatic organisms. This is why natural compounds are increasingly being investigated and used in cosmetic and pharmaceutical sunscreens. Some of these compounds are widely available, non-toxic, safer for use, and have considerable UV protective properties and less side effects. Plant-based compounds such as flavonoids can absorb UVA and UVB rays and possess antioxidant, anticarcinogenic, and anti-inflammatory effects that contribute to photoprotection. Apart from flavonoids, other natural products such as certain vegetable oils, carotenoids, stilbenes, and ferulic acid also have UV-absorbing properties. Some vitamins might also be beneficial for skin protection due to their antioxidant activity. Therefore, the aim of this research was to gain insight into the potential of natural compounds to replace or reduce the amount of conventional UV filters, based on recent research.

Published
2024
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2. Phytochemical Composition of Different Red Clover Genotypes Based on Plant Part and Genetic Traits

Author

Mira Mikulić, Milica Atanacković Krstonošić, Nebojša Kladar, Sanja Vasiljević, Snežana Katanski, Zlatica Mamlić, Dušan Rakić, and Jelena Cvejić

Subjects
Trifolium pratense, isoflavones, ploidy, HPLC, total phenolic content, antioxidant activity, Chemical technology, TP1-1185
Abstract

Red clover (Trifolium pratense L.) is an important legume that is also known as a rich source of isoflavones, which are compounds with mild estrogenic activity. Therefore, this plant is often used as a raw material in the production of dietary supplements recommended in menopause. Many factors can influence isoflavone content, but those genetically related are considered to be the most important. Therefore, the aim of this study was to evaluate the phytochemical profile of different plant parts of 30 red clover genotypes grouped according to ploidy and country of seed origin by analyzing the content of dominant isoflavones, total phenolic content (TPC) and antioxidant activity. It was found that there are significant differences in the examined traits among plant parts. Red clover leaves had the highest total isoflavone content, with biochanin A as the dominant compound, while flower extracts had the highest TPC and antioxidant activity. Diploid and tetraploid genotypes were significantly different concerning the content of daidzein, genistein, formononetin and TPC with higher quantities in tetraploid samples. On the other hand, seed origin was not a useful separating factor for the analyzed samples. The results of this research indicate that ploidy, as a previously poorly studied factor, could influence isoflavone content in red clover.

Published
2023
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5. Can environmental pollutant bisphenol A increase metabolic risk in polycystic ovary syndrome?

Author

Maja Milanović, Artur Bjelica, Stefan Stojanoski, Nataša Milošević, Jan Sudji, Milica Atanacković Krstonošić, Natasa Milic, and Milica Medic Stojanoska

Subjects
Adult, 0301 basic medicine, endocrine system, medicine.medical_specialty, Adolescent, endocrine system diseases, medicine.drug_class, Clinical Biochemistry, Urine, Biochemistry, Gas Chromatography-Mass Spectrometry, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Phenols, Risk Factors, Internal medicine, medicine, Hyperinsulinemia, Humans, Benzhydryl Compounds, Testosterone, urogenital system, business.industry, Biochemistry (medical), nutritional and metabolic diseases, General Medicine, medicine.disease, Androgen, Polycystic ovary, Obesity, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, Environmental Pollutants, Female, business, hormones, hormone substitutes, and hormone antagonists, Dyslipidemia, Polycystic Ovary Syndrome
Abstract

Background Bisphenol A (BPA), a widespread industrial substance is recognized as endocrine disrupting chemical and therefore could be associated with polycystic ovary syndrome (PCOS) related metabolic disturbances. Patients In this study 29 women of reproductive age with diagnosed PCOS were enrolled. Methods BPA in urine samples was analyzed by gas chromatography-mass spectrometry. Results BPA was detected in urines of 48.28% participants. The waist-to-height ratio (WtHR) was statistically significant higher in PCOS BPA+ in comparison to PCOS BPA− women (p = 0.046). PCOS BPA+ women had 6.88 times (95%Cl 1.3481–35.0600, z = 2.319, p = 0.020) higher risk for waist circumference above 80 cm and 4.95 odds (95%Cl 1.0169–24.096, z = 1.981, p = 0.048) to have WtHR over 0.5 when compared to PCOS BPA−. Statistically significant positive association between BPA urine concentrations and insulin serum levels (p = 0.038) was obtained. BPA urine values were associated with elevated HOMA-IR values and reduced HDL levels with moderate significance (p = 0.079 and p = 0.061, respectively). Also, there was 3.75 times (95%Cl 0.7936–17.7203, z = 1.668, p = 0.095) higher risk for PCOS BPA+ women to have testosterone levels above reference values. Conclusion The obtained results suggested that the BPA exposition in PCOS women was followed by increased metabolic risk through promotion of obesity, especially the visceral type, hyperinsulinemia, insulin resistance, dyslipidemia and elevated androgen levels.

Published
2020
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6. Polyphenols

Author

Jelena Cvejić, Milica Atanacković Krstonošić, Mira Mikulić, and Uroš Miljić

Published
2022
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7. List of Contributors

Author

Maliha Afreen, Paola Aiello, Milica Atanacković Krstonošić, Francisco J. Barba, Lillian Barros, Samuel Adegoke Chetachukwu, Jelena Cvejić, Maria Inês Dias, Silvina R. Drago, Silvina Rosa Drago, Isabel C.F.R. Ferreira, Eliana Noemi Fissore, Ana Fita, Charis M. Galanakis, José David García Benzal, Cristina García Viguera, Lia Noemi Gerschenson, Carla Guijarro-Real, Boon Chin Hoe, Seyed Vali Hosseini, Raffaella Inchingolo, Anet Režek Jambrak, Pop Oana Lelia, Mira Mikulić, Uroš Miljić, Silvia A. Moreira, Diego A. Moreno, Jayesree Nagarajan, K. Nagendra Prasad, Chien Wei Ooi, Carla Pereira, José Pinela, Arumugam Priyangaa, Jaime Prohens, Rui P. Queirós, Ramakrishnan Nagasundara Ramanan, Maria Teresa Rodriguez-Estrada, Ana Maria Rojas, Custódio Lobo Roriz, Mauro D. Santos, Jorge A. Saraiva, Dubravka Škevin, Ramona Suharoschi, Reza Tahergorabi, Urszula Tylewicz, İlknur Uçak, Débora Villaño, and Zhenzhou Zhu

Published
2022
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11. Contributors

Author

R. Abhishek Biswal, Şevki Adem, Ahmad Adnan, Nafees Ahemad, Hammad Ahmed, Sumia Akram, Ahmed Alafnan, Farooq Anwar, Sirajudheen Anwar, Laiba Arshad, Nayara A. Artero, Rizwan Ashraf, Mehwish Aslam, Milica Atanacković Krstonošić, Aima Iram Batool, Haq Nawaz Bhatti, Thacyana T. Carvalho, Rubia Casagrande, Bruce K. Cassels, Sebastián Castro-Saavedra, Sofia Chanioti, Ranil Coorey, Jelena Cvejić, Aleksandra Cvetanović, Baishakhi De, Savita Devi, Suparna Devu, Nayara Braga Emidio, Karen Hariantty Estévez-Sánchez, Victor Fattori, Camila R. Ferraz, Anelise Franciosi, Gonzalo Fuentes-Barros, Ma’Aruf Abd Ghani, Esther Gómez-Mejía, Tridib Kumar Goswami, Syeda Mariam Hasany, Ghulam Hussain, Norhayati Hussain, Sidra Ihsan, Izzreen Ishak, Maria Katsouli, Gustavo Heinrich Lang, Mª Eugenia León-González, Alison Lovegrove, Ramasamy Madhumathi, Marília F. Manchope, Setti Sudharshan Meenambiga, Murlidhar Meghwal, Tahir Mehmood, M. Angela A. Meireles, Francesca Melini, Valentina Melini, Mira Mikulić, Muhammad Mushtaq, Javaria Nawaz, Carlos Enrique Ochoa-Velasco, Maurício de Oliveira, Chirle de Oliveira Raphaelli, Vivek Pazhamalai, Tan Chin Ping, Rahman Qadir, Fernanda S. Rasquel-Oliveira, Azhar Rasul, Muhammad Fayyaz ur Rehman, Ammara Riaz, Noelia Rosales-Conrado, Héctor Ruiz-Espinosa, Irving Israel Ruiz-López, Ayesha Sadiqa, Punniavan Sakthiselvan, Hammad Saleem, Ádina L. Santana, Iqra Sarfraz, Asma Shafique, Yasser Shahbazi, Nassim Shavisi, Himani Singh, A.S. Smiline Girija, Cristian Suárez-Rozas, Qudsia Tabassam, Ayesha Tabassum, Sajida Tabassum, Constantina Tzia, Ilknur Ucak, Waldiceu A. Verri Jr, Fabiana T.M.C. Vicentini, Ammara Waheed, Iqra Zahid, and Muhammad Kashif Zahoor

Published
2021
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12. Polyphenols

Author

Mira Bursać, Uroš Miljić, Milica Atanacković Krstonošić, and Jelena Hogervorst Cvejić

Subjects
0301 basic medicine, 030109 nutrition & dietetics, Computer science, Emerging technologies, media_common.quotation_subject, Organoleptic, 04 agricultural and veterinary sciences, 040401 food science, 03 medical and health sciences, 0404 agricultural biotechnology, Nutraceutical, Functional food, Polyphenol, Quality (business), Biochemical engineering, media_common
Abstract

This chapter outlines the current trends and innovative techniques in the processing of natural polyphenolic compounds and how emerging technologies affect the functionality of these nutraceutical and functional food components. The bioavailability of polyphenols as nutrients, their transformations by intestinal microbiota as well specific interactions are discussed, and some preservation techniques are presented. Taking into account that the loss of phytonutrients becomes more significant as foods are processed, implementation of emerging technologies preserving nutritional and functional properties is of high importance for the overall quality of a product, as discussed in this chapter. Emerging technologies used to ensure maximal nutritional and functional properties as well as the overall quality of a product are described. Innovative extraction and processing techniques for the recovery of beneficial phenolic compounds from food sources as well as their effects on functional properties are also highlighted. Considering that phenolics may strongly affect the organoleptic properties of products, the innovative applications and the effects on the sensory quality of food and beverage products are also covered.

Published
2017
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13. List of Contributors

Author

Milica Atanacković Krstonošić, Francisco J. Barba, Mira Bursać, Silvina Rosa Drago, Eliana Noemi Fissore, Charis M. Galanakis, Cristina García-Viguera, Lia Noemi Gerschenson, Amadeo Gironés-Vilaplana, Jelena Hogervorst Cvejić, Seyed Vali Hosseini, Raffaella Inchingolo, Anet Režek Jambrak, Nagendra Prasad Krishnamurthy, Javier Marhuenda, Uroš Miljić, Silvia A. Moreira, Diego A. Moreno, Jayesree Nagarajan, Rui P. Queirós, Mavinakere Eshwaraiah Raghunandan, Ramakrishnan Nagasundara Ramanan, Maria Teresa Rodriguez-Estrada, Ana Maria Rojas, Mauro D. Santos, Jorge A. Saraiva, Dubravka Škevin, Reza Tahergorabi, Urszula Tylewicz, Débora Villaño, and Zhenzhou Zhu

Published
2017
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