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1. ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016

Author: Velasquez, T., Mackey, G., Lusk, J., Kyle, U. G., Fontenot, T., Marshall, P., Shekerdemian, L. S., Coss-Bu, J. A., Nishigaki, A., Yatabe, T., Tamura, T., Yamashita, K., Yokoyama, M., Ruiz-Rodriguez, J. C., Encina, B., Belmonte, R., Troncoso, I., Tormos, P., Riveiro, M., Baena, J., Sanchez, A., Bañeras, J., Cordón, J., Duran, N., Ruiz, A., Caballero, J., Nuvials, X., Riera, J., Serra, J., Rutten, A. M. F., van Ieperen, S. N. M., Der Kinderen, E. P. H. M., Van Logten, T., Kovacikova, L., Skrak, P., Zahorec, M., Kyle, U. G., Akcan-Arikan, A., Silva, J. C., Mackey, G., Lusk, J., Goldsworthy, M., Shekerdemian, L. S., Coss-Bu, J. A., Wood, D., Harrison, D., Parslow, R., Davis, P., Pappachan, J., Goodwin, S., Ramnarayan, P., Chernyshuk, S., Yemets, H., Zhovnir, V., Pulitano’, S. M., De Rosa, S., Mancino, A., Villa, G., Tosi, F., Franchi, P., Conti, G., Patel, B., Khine, H., Shah, A., Sung, D., Singer, L., Haghbin, S., Inaloo, S., Serati, Z., Idei, M., Nomura, T., Yamamoto, N., Sakai, Y., Yoshida, T., Matsuda, Y., Yamaguchi, Y., Takaki, S., Yamaguchi, O., Goto, T., Longani, N., Medar, S., Abdel-Aal, I. R., El Adawy, A. S., Mohammed, H. M. E. H., Mohamed, A. N., Parry, S. M., Knight, L. D., Denehy, L., De Morton, N., Baldwin, C. E., Sani, D., Kayambu, G., da Silva, V. Z. M., Phongpagdi, P., Puthucheary, Z. A., Granger, C. L., Rydingsward, J. E., Horkan, C. M., Christopher, K. B., McWilliams, D., Jones, C., Reeves, E., Atkins, G., Snelson, C., Aitken, L. M., Rattray, J., Kenardy, J., Hull, A. M., Ullman, A., Le Brocque, R., Mitchell, M., Davis, C., Macfarlane, B., Azevedo, J. C., Rocha, L. L., De Freitas, F. F. M., Cavalheiro, A. M., Lucinio, N. M., Lobato, M. S., Ebeling, G., Kraegpoeth, A., Laerkner, E., De Brito-Ashurst, I., White, C., Gregory, S., Forni, L. G., Flowers, E., Curtis, A., Wood, C. A., Siu, K., Venkatesan, K., Muhammad, J. B. H., Ng, L., Seet, E., Baptista, N., Escoval, A., Tomas, E., Agrawal, R., Mathew, R., Varma, A., Dima, E., Charitidou, E., Perivolioti, E., Pratikaki, M., Vrettou, C., Giannopoulos, A., Zakynthinos, S., Routsi, C., Atchade, E., Houzé, S., Jean-Baptiste, S., Thabut, G., Genève, C., Tanaka, S., Lortat-Jacob, B., Augustin, P., Desmard, M., Montravers, P., de Molina, F. J. González, Barbadillo, S., Alejandro, R., Álvarez-Lerma, F., Vallés, J., Catalán, R. M., Palencia, E., Jareño, A., Granada, R. M., Ignacio, M. L., Cui, N., Liu, D., Wang, H., Su, L., Qiu, H., Li, R., Jaffal, K., Rouzé, A., Poissy, J., Sendid, B., Nseir, S., Paramythiotou, E., Rizos, M., Frantzeskaki, F., Antoniadou, A., Vourli, S., Zerva, L., Armaganidis, A., Riera, J., Gottlieb, J., Greer, M., Wiesner, O., Martínez, M., Acuña, M., Rello, J., Welte, T., Atchade, E., Mignot, T., Houzé, S., Jean-Baptiste, S., Thabut, G., Lortat-Jacob, B., Tanaka, S., Augustin, P., Desmard, M., Montravers, P., Soussi, S., Dudoignon, E., Ferry, A., Chaussard, M., Benyamina, M., Alanio, A., Touratier, S., Chaouat, M., Lafaurie, M., Mimoun, M., Mebazaa, A., Legrand, M., Sheils, M. A., Patel, C., Mohankumar, L., Akhtar, N., Noriega, S. K. Pacheco, Aldana, N. Navarrete, León, J. L. Ávila, Baquero, J. Durand, Bernal, F. Fernández, Ahmadnia, E., Hadley, J. S., Millar, M., Hall, D., Hewitt, H., Yasuda, H., Sanui, M., Komuro, T., Kawano, S., Andoh, K., Yamamoto, H., Noda, E., Hatakeyama, J., Saitou, N., Okamoto, H., Kobayashi, A., Takei, T., Matsukubo, S., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Gimillo, M. Rodriguez, Barinas, O. Diaz, Cortes, M. L. Blasco, Franco, J. Ferreres, Roca, J. M. Segura, Carratalá, A., Gonçalves, B., Turon, R., Mendes, A., Miranda, F., Mata, P. J., Cavalcanti, D., Melo, N., Lacerda, P., Kurtz, P., Righy, C., Rosario, L. E. de la Cruz, Lesmes, S. P. Gómez, Romero, J. C. García, Herrera, A. N. García, Pertuz, E. D. Díaz, Sánchez, M. J. Gómez, Sanz, E. Regidor, Hualde, J. Barado, Hernández, A. Ansotegui, Irazabal, J. M. Guergué, Spatenkova, V., Bradac, O., Suchomel, P., Urli, T., Lazzeri, E. Heusch, Aspide, R., Zanello, M., Perez-Borrero, L., Garcia-Alvarez, J. M., Arias-Verdu, M. D., Aguilar-Alonso, E., Rivera-Fernandez, R., Mora-Ordoñez, J., De La Fuente-Martos, C., Castillo-Lorente, E., Guerrero-Lopez, F., Lesmes, S. P. Gómez, Rosario, L. E. De la Cruz, Pertuz, E. D. Díaz, Hernández, A. Ansotegui, Romero, J. C. García, Sánchez, M. J. Gómez, Herrera, A. N. García, Ramírez, J. Roldán, Sanz, E. Regidor, Hualde, J. Barado, León, J. P. Tirapu, Navarro-Guillamón, L., Cordovilla-Guardia, S., Iglesias-Santiago, A., Guerrero-López, F., Fernández-Mondéjar, E., Vidal, A., Perez, M., Juez, A., Arias, N., Colino, L., Perez, J. L., Pérez, H., Calpe, P., Alcala, M. A., Robaglia, D., Perez, C., Lan, S. K., Cunha, M. M., Moreira, T., Santos, F., Lafuente, E., Fernandes, M. J., Silva, J. G., Rosario, L. E. de la Cruz, Lesmes, S. P. Gómez, Herrera, A. N. García, Romero, J. C. García, Pertuz, E. D. Díaz, Sánchez, M. J. Gómez, Sanz, E. Regidor, Echeverría, J. G. Armando, Hernández, A. Ansotegui, Hualde, J. Barado, Podlepich, V., Sokolova, E., Alexandrova, E., Lapteva, K., Kurtz, P., Shuinotsuka, C., Rabello, L., Vianna, G., Reis, A., Cairus, C., Salluh, J., Bozza, F., Torres, J. C. Barrios, Araujo, N. J. Fernández, García-Olivares, P., Keough, E., Dalorzo, M., Tang, L. K., De Sousa, I., Díaz, M., Marcos-Zambrano, L. J., Guerrero, J. E., Gomez, S. E. Zamora, Lopez, G. D. Hernandez, Cuellar, A. I. Vazquez, Nieto, O. R. Perez, Gonzalez, J. A. Castanon, Bhasin, D., Rai, S., Singh, H., Gupta, O., Bhattal, M. K., Sampley, S., Sekhri, K., Nandha, R., Aliaga, F. A., Olivares, F., Appiani, F., Farias, P., Alberto, F., Hernández, A., Pons, S., Sonneville, R., Bouadma, L., Neuville, M., Mariotte, E., Radjou, A., Lebut, J., Chemam, S., Voiriot, G., Dilly, M. P., Mourvillier, B., Dorent, R., Nataf, P., Wolff, M., Timsit, J. F., Ediboglu, O., Ataman, S., Ozkarakas, H., Kirakli, C., Vakalos, A., Avramidis, V., Obukhova, O., Kurmukov, I. A., Kashiya, S., Golovnya, E., Baikova, V. N., Ageeva, T., Haritydi, T., Kulaga, E. V., Rios-Toro, J. J., Perez-Borrero, L., Aguilar-Alonso, E., Arias-Verdu, M. D., Garcia-Alvarez, J. M., Lopez-Caler, C., De La Fuente-Martos, C., Rodriguez-Fernandez, S., Sanchez-Orézzoli, M. Gomez, Martin-Gallardo, F., Nikhilesh, J., Joshi, V., Villarreal, E., Ruiz, J., Gordon, M., Quinza, A., Gimenez, J., Piñol, M., Castellanos, A., Ramirez, P., Jeon, Y. D., Jeong, W. Y., Kim, M. H., Jeong, I. Y., Ahn, M. Y., Ahn, J. Y., Han, S. H., Choi, J. Y., Song, Y. G., Kim, J. M., Ku, N. S., Shah, H., Kellner, F., Rezai, F., Mistry, N., Yodice, P., Ovnanian, V., Fless, K., Handler, E., Alejos, R. Martínez, Romeu, J. D. Martí, Antón, D. González, Quinart, A., Martí, A. Torres, Llaurado-Serra, M., Lobo-Civico, A., Ventura-Rosado, A., Piñol-Tena, A., Pi-Guerrero, M., Paños-Espinosa, C., Peralvo-Bernat, M., Marine-Vidal, J., Gonzalez-Engroba, R., Montesinos-Cerro, N., Treso-Geira, M., Valeiras-Valero, A., Martinez-Reyes, L., Sandiumenge, A., Jimenez-Herrera, M. F., Helyar, S., Riozzi, P., Noon, A., Hallows, G., Cotton, H., Keep, J., Hopkins, P. A., Taggu, A., Renuka, S., Sampath, S., Rood, P. J. T., Frenzel, T., Verhage, R., Bonn, M., Pickkers, P., van der Hoeven, J. G., van den Boogaard, M., Corradi, F., Melnyk, L., Moggia, F., Pienovi, R., Adriano, G., Brusasco, C., Mariotti, L., Lattuada, M., Bloomer, M. J., Coombs, M., Ranse, K., Endacott, R., Maertens, B., Blot, K., Blot, S., Amerongen, M. P. van Nieuw, van der Heiden, E. S., Twisk, J. W. R., Girbes, A. R. J., Spijkstra, J. J., Riozzi, P., Helyar, S., Cotton, H., Hallows, G., Noon, A., Bell, C., Peters, K., Feehan, A., Keep, J., Hopkins, P. A., Churchill, K., Hawkins, K., Brook, R., Paver, N., Endacott, R., Maistry, N., van Wijk, A., Rouw, N., van Galen, T., Evelein-Brugman, S., Taggu, A., Krishna, B., Sampath, S., Putzu, A., Fang, M., Berto, M. Boscolo, Belletti, A., Cassina, T., Cabrini, L., Mistry, M., Alhamdi, Y., Welters, I., Abrams, S. T., Toh, C. H., Han, H. S., Gil, E. M., Lee, D. S., Park, C. M., Winder-Rhodes, S., Lotay, R., Doyle, J., Ke, M. W., Huang, W. C., Chiang, C. H., Hung, W. T., Cheng, C. C., Lin, K. C., Lin, S. C., Chiou, K. R., Wann, S. R., Shu, C. W., Kang, P. L., Mar, G. Y., Liu, C. P., Dubó, S., Aquevedo, A., Jibaja, M., Berrutti, D., Labra, C., Lagos, R., García, M. F., Ramirez, V., Tobar, M., Picoita, F., Peláez, C., Carpio, D., Alegría, L., Hidalgo, C., Godoy, K., Bakker, J., Hernández, G., Sadamoto, Y., Katabami, K., Wada, T., Ono, Y., Maekawa, K., Hayakawa, M., Sawamura, A., Gando, S., Marin-Mateos, H., Perez-Vela, J. L., Garcia-Gigorro, R., Peiretti, M. A. Corres, Lopez-Gude, M. J., Chacon-Alves, S., Renes-Carreño, E., Montejo-González, J. C., Parlevliet, K. L., Touw, H. R. W., Beerepoot, M., Boer, C., Elbers, P. W. G., Tuinman, P. R., Abdelmonem, S. A., Helmy, T. A., El Sayed, I., Ghazal, S., Akhlagh, S. H., Masjedi, M., Hozhabri, K., Kamali, E., Zýková, I., Paldusová, B., Sedlák, P., Morman, D., Youn, A. M., Ohta, Y., Sakuma, M., Bates, D., Morimoto, T., Su, P. L., Chang, W. Y., Lin, W. C., Chen, C. W., Facchin, F., Zarantonello, F., Panciera, G., De Cassai, A., Venrdramin, A., Ballin, A., Tonetti, T., Persona, P., Ori, C., Del Sorbo, L., Rossi, S., Vergani, G., Cressoni, M., Chiumello, D., Chiurazzi, C., Brioni, M., Algieri, I., Tonetti, T., Guanziroli, M., Colombo, A., Tomic, I., Colombo, A., Crimella, F., Carlesso, E., Gasparovic, V., Gattinoni, L., Neto, A. Serpa, Schmidt, M., Pham, T., Combes, A., de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Katira, B. H., Engelberts, D., Giesinger, R. E., Ackerley, C., Yoshida, T., Zabini, D., Otulakowski, G., Post, M., Kuebler, W. M., McNamara, P. J., Kavanagh, B. P., Pirracchio, R., Rigon, M. Resche, Carone, M., Chevret, S., Annane, D., Eladawy, S., El-Hamamsy, M., Bazan, N., Elgendy, M., De Pascale, G., Vallecoccia, M. S., Cutuli, S. L., Di Gravio, V., Pennisi, M. A., Conti, G., Antonelli, M., Andreis, D. T., Khaliq, W., Singer, M., Hartmann, J., Harm, S., Carmona, S. Alcantara, Almudevar, P. Matia, Abellán, A. Naharro, Ramos, J. Veganzones, Pérez, L. Pérez, Valbuena, B. Lobo, Sanz, N. Martínez, Simón, I. Fernández, Arrigo, M., Feliot, E., Deye, N., Cariou, A., Guidet, B., Jaber, S., Leone, M., Resche-Rigon, M., Baron, A. Vieillard, Legrand, M., Gayat, E., Mebazaa, A., Balik, M., Kolnikova, I., Maly, M., Waldauf, P., Tavazzi, G., Kristof, J., Herpain, A., Su, F., Post, E., Taccone, F., Vincent, J. L., Creteur, J., Lee, C., Hatib, F., Jian, Z., Buddi, S., Cannesson, M., Fileković, S., Turel, M., Knafelj, R., Gorjup, V., Stanić, R., Gradišek, P., Cerović, O., Mirković, T., Noč, M., Tirkkonen, J., Hellevuo, H., Olkkola, K. T., Hoppu, S., Lin, K. C., Hung, W. T., Chiang, C. C., Huang, W. C., Juan, W. C., Lin, S. C., Cheng, C. C., Lin, P. H., Fong, K. Y., Hou, D. S., Kang, P. L., Wann, S. R., Chen, Y. S., Mar, G. Y., Liu, C. P., Paul, M., Bougouin, W., Geri, G., Dumas, F., Champigneulle, B., Legriel, S., Charpentier, J., Mira, J. P., Sandroni, C., Cariou, A., Zimmerman, J., Sullivan, E., Noursadeghi, M., Fox, B., Sampson, D., McHugh, L., Yager, T., Cermelli, S., Seldon, T., Bhide, S., Brandon, R. A., Brandon, R. B., Zwaag, J., Beunders, R., Pickkers, P., Kox, M., Gul, F., Arslantas, M. K., Genc, D., Zibandah, N., Topcu, L., Akkoc, T., Cinel, I., Greco, E., Lauretta, M. P., Andreis, D. T., Singer, M., Garcia, I. Palacios, Cordero, M., Martin, A. Diaz, Pallás, T. Aldabó, Montero, J. Garnacho, Rey, J. Revuelto, Malo, L. Roman, Montoya, A. A. Tanaka, Martinez, A. D. C. Amador, Ayala, L. Y. Delgado, Zepeda, E. Monares, Granillo, J. Franco, Sanchez, J. Aguirre, Alejo, G. Camarena, Cabrera, A. Rugerio, Montenegro, A. Pedraza, Pham, T., Beduneau, G., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, P. G., Frat, J. P., Constan, A., Chrétien, J. M., Mancebo, J., Mercat, A., Richard, J. C. M., Brochard, L., Soilemezi, E., Koco, E., Savvidou, S., Nouris, C., Matamis, D., Di Mussi, R., Spadaro, S., Volta, C. A., Mariani, M., Colaprico, A., Antonio, C., Bruno, F., Grasso, S., Rodriguez, A., Martín-Loeches, I., Díaz, E., Masclans, J. R., Gordo, F., Solé-Violán, J., Bodí, M., Avilés-Jurado, F. X., Trefler, S., Magret, M., Reyes, L. F., Marín-Corral, J., Yebenes, J. C., Esteban, A., Anzueto, A., Aliberti, S., Restrepo, M. I., Larsson, J. Skytte, Redfors, B., Ricksten, S. E., Haines, R., Powell-Tuck, J., Leonard, H., Ostermann, M., Berthelsen, R. E., Itenov, T. S., Perner, A., Jensen, J. U., Ibsen, M., Jensen, A. E. K., Bestle, M. H., Bucknall, T., Dixon, J., Boa, F., MacPhee, I., Philips, B. J., Doyle, J., Saadat, F., Samuels, T., Huddart, S., McCormick, B., DeBrunnar, R., Preece, J., Swart, M., Peden, C., Richardson, S., Forni, L., Kalfon, P., Baumstarck, K., Estagnasie, P., Geantot, M. A., Berric, A., Simon, G., Floccard, B., Signouret, T., Boucekine, M., Fromentin, M., Nyunga, M., Sossou, A., Venot, M., Robert, R., Follin, A., Renault, A., Garrouste, M., Collange, O., Levrat, Q., Villard, I., Thévenin, D., Pottecher, J., Patrigeon, R. G., Revel, N., Vigne, C., Mimoz, O., Auquier, P., Pawar, S., Jacques, T., Deshpande, K., Pusapati, R., Wood, B., Pulham, R. A., Wray, J., Brown, K., Pierce, C., Nadel, S., Ramnarayan, P., Azevedo, J. R., Montenegro, W. S., Rodrigues, D. P., Sousa, S. C., Araujo, V. F., Leitao, A. L., Prazeres, P. H., Mendonca, A. V., Paula, M. P., Das Neves, A., Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Lischinsky, A., Veronesi, M., Emmerich, M., Descotte, E., Juliarena, A., Bisso, M. Carboni, Grando, M., Tapia, A., Camargo, M., Ulla, D. Villani, Corzo, L., dos Santos, H. Placido, Ramos, A., Doglia, J. A., Estenssoro, E., Carbonara, M., Magnoni, S., Donald, C. L. Mac, Shimony, J. S., Conte, V., Triulzi, F., Stretti, F., Macrì, M., Snyder, A. Z., Stocchetti, N., Brody, D. L., Podlepich, V., Shimanskiy, V., Savin, I., Lapteva, K., Chumaev, A., Tjepkema-Cloostermans, M. C., Hofmeijer, J., Beishuizen, A., Hom, H., Blans, M. J., van Putten, M. J. A. M., Longhi, L., Frigeni, B., Curinga, M., Mingone, D., Beretta, S., Patruno, A., Gandini, L., Vargiolu, A., Ferri, F., Ceriani, R., Rottoli, M. R., Lorini, L., Citerio, G., Pifferi, S., Battistini, M., Cordolcini, V., Agarossi, A., Di Rosso, R., Ortolano, F., Stocchetti, N., Lourido, C. Mora, Cabrera, J. L. Santana, Santana, J. D. Martín, Alzola, L. Melián, del Rosario, C. García, Pérez, H. Rodríguez, Torrent, R. Lorenzo, Eslami, S., Dalhuisen, A., Fiks, T., Schultz, M. J., Hanna, A. Abu, Spronk, P. E., Wood, M., Maslove, D., Muscedere, J., Scott, S. H., Saha, T., Hamilton, A., Petsikas, D., Payne, D., Boyd, J. G., Puthucheary, Z. A., McNelly, A. S., Rawal, J., Connolly, B., McPhail, M. J., Sidhu, P., Rowlerson, A., Moxham, J., Harridge, S. D., Hart, N., Montgomery, H. E., Jovaisa, T., Thomas, B., Gupta, D., Wijayatilake, D. S., Shum, H. P., King, H. S., Chan, K. C., Tang, K. B., Yan, W. W., Arias, C. Castro, Latorre, J., De La Rica, A. Suárez, Garrido, E. Maseda, Feijoo, A. Montero, Gancedo, C. Hernández, Tofiño, A. López, Rodríguez, F. Gilsanz, Gemmell, L. K., Campbell, R., Doherty, P., MacKay, A., Singh, N., Vitaller, S., Nagib, H., Prieto, J., Del Arco, A., Zayas, B., Gomez, C., Tirumala, S., Pasha, S. A., Kumari, B. K., Martinez-Lopez, P., Puerto-Morlán, A., Nuevo-Ortega, P., Pujol, L. Martinez, Dolset, R. Algarte, González, B. Sánchez, Riera, S. Quintana, Álvarez, J. Trenado, Quintana, S., Martínez, L., Algarte, R., Sánchez, B., Trenado, J., Tomas, E., Brock, N., Viegas, E., Filipe, E., Cottle, D., Traynor, T., Martínez, M. V. Trasmonte, Márquez, M. Pérez, Gómez, L. Colino, Martínez, N. Arias, Muñoz, J. M. Milicua, Bellver, B. Quesada, Varea, M. Muñoz, Llorente, M. Á. Alcalá, Calvo, C. Pérez, Hillier, S. D., Faulds, M. C., Hendra, H., Lawrence, N., Maekawa, K., Hayakawa, M., Ono, Y., Kodate, A., Sadamoto, Y., Tominaga, N., Mizugaki, A., Murakami, H., Yoshida, T., Katabami, K., Wada, T., Sawamura, A., Gando, S., Silva, S., Kerhuel, L., Malagurski, B., Citerio, G., Chabanne, R., Laureys, S., Puybasset, L., Nobile, L., Pognuz, E. R., Rossetti, A. O., Verginella, F., Gaspard, N., Creteur, J., Ben-Hamouda, N., Oddo, M., Taccone, F. S., Ono, Y., Hayakawa, M., Iijima, H., Maekawa, K., Kodate, A., Sadamoto, Y., Mizugaki, A., Murakami, H., Katabami, K., Wada, T., Sawamura, A., Gando, S., Kodate, A., Katabami, K., Wada, T., Ono, Y., Maekawa, K., Hayakawa, M., Sawamura, A., Gando, S., Andersen, L. W., Raymond, T., Berg, R., Nadkarni, V., Grossestreuer, A., Kurth, T., Donnino, M., Krüger, A., Ostadal, P., Janotka, M., Vondrakova, D., Kongpolprom, N., Cholkraisuwat, J., Pekkarinen, P. T., Ristagno, G., Masson, S., Latini, R., Bendel, S., Ala-Kokko, T., Varpula, T., Vaahersalo, J., Hoppu, S., Tiainen, M., Mion, M. M., Plebani, M., Pettilä, V., Skrifvars, M.B., Son, Y., Kim, K. S., Suh, G. J., Kwon, W. Y., Ko, J. I., Park, M. J., Cavicchi, F. Zama, Iesu, E., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Tanaka, H., Otani, N., Ode, S., Ishimatsu, S., Martínez, L., Algarte, R., Sánchez, B., Romero, I., Martínez, F., Quintana, S., Trenado, J., Vondrakova, D., Ostadal, P., Kruger, A., Janotka, M., Malek, F., Neuzil, P., Yeh, Y. C., Chen, Y. S., Wang, C. H., Huang, C. H., Chao, A., Lee, C. T., Lai, C. H., Chan, W. S., Cheng, Y. J., Sun, W. Z., Kaese, S., Horstmann, C., Lebiedz, P., Mourad, M., Gaudard, P., Eliet, J., Zeroual, N., Colson, P., Ostadal, P., Mlcek, M., Hrachovina, M., Kruger, A., Vondrakova, D., Janotka, M., Mates, M., Hala, P., Kittnar, O., Neuzil, P., Jacky, A., Rudiger, A., Spahn, D. R., Bettex, D. A., Kara, A., Akin, S., Dos reis Miranda, D., Struijs, A., Caliskan, K., van Thiel, R. J., Dubois, E. A., de Wilde, W., Zijlstra, F., Gommers, D., Ince, C., Marca, L., Xini, A., Mongkolpun, W., Cordeiro, C. P. R., Leite, R. T., Lheureux, O., Bader, A., Rincon, L., Santacruz, C., Preiser, J. C., Chao, A., Chao, A. S., Chen, Y. S., Kim, W., Ahn, C., Cho, Y., Lim, T. H., Oh, J., Choi, K. S., Jang, B. H., Ha, J. K., Mecklenburg, A., Stamm, J., Soeffker, G., Kubik, M., Sydow, K., Reichenspurner, H., Kluge, S., Braune, S., Bergantino, B., Ruberto, F., Magnanimi, E., Privato, E., Zullino, V., Bruno, K., Pugliese, F., Sales, G., Girotto, V., Vittone, F., Brazzi, L., Fritz, C., Kimmoun, A., Vanhuyse, F., Trifan, B., Orlowski, S., Albuisson, E., Tran, N., Levy, B., Chhor, V., Joachim, J., Follin, A., Champigneulle, B., Chatelon, J., Fave, G., Mantz, J., Pirracchio, R., Diaz, D. Díaz, Villanova, M., Aguirregabyria, M., Andrade, G., López, L., Palencia, E., John, G., Cowan, R., Hart, R., Lake, K., Litchfield, K., Song, J. W., Lee, Y. J., Cho, Y. J., Choi, S., Vermeir, P., Vandijck, D., Blot, S., Mariman, A., Verhaeghe, R., Deveugele, M., Vogelaers, D., Chok, L., Bachli, E. B., Bettex, D., Cottini, S. R., Keller, E., Maggiorini, M., Schuepbach, R., Fiks, T., Stiphout, C., Grevelink, M., Vaneker, I., Ruijter, A., Buise, M., Spronk, P. E., Tena, S. Altaba, Barrachina, L. Galarza, Portillo, J. H. Rodriguez, Aznar, G. Pagés, Campos, L. Mateu, Sellés, M. D. Ferrándiz, Tomás, M. Arlandis, Muncharaz, A. Belenguer, Skinner, L., Monsalvo, S., Olavarria, E., Stümpfle, R., Na, S. J., Park, J., Chung, C. R., Park, C. M., Suh, G. Y., Yang, J. H., Witter, T., Brousseau, C., Butler, M. B., Erdogan, M., Dougall, P. C. Mac, Green, R. S., Abbott, T. E. F., Torrance, H. D. T., Cron, N., Vaid, N., Emmanuel, J., Siddiqui, S. S., Prabu, N., Chaudhari, H. K., Patil, V. P., Divatia, J. V., Solanki, S., Kulkarni, A. P., Gutierrez, L. A. Rincon, Bader, A., Brasseur, A., Lheureux, O., Vincent, J. L., Creteur, J., Taccone, F. S., Hempel, D., Stauffert, N., Recker, F., Schröder, T., Reusch, S., Schleifer, J., Breitkreutz, R., Sjövall, F., Perner, A., Møller, M. Hylander, Moraes, R. B., Borges, F. K., Guillen, J. A. V., Zabaletta, W. J. C., Ruiz-Ramos, J., Ramirez, P., Marqués-Miñana, M. R., Villarreal, E., Gordon, M., Sosa, M., Concha, P., Castellanos, A., Menendez, R., Ramírez, C. Sánchez, Santana, M. Cabrera, Balcázar, L. Caipe, Escalada, S. Hípola, Viera, M. A. Hernández, Vázquez, C. F. Lübbe, Díaz, J. J. Díaz, Campelo, F. Artiles, Monroy, N. Sangil, Santana, P. Saavedra, Santana, S. Ruiz, Gutiérrez-Pizarraya, A., Garnacho-Montero, J., Martin, C., Baumstarck, K., Leone, M., Martín-Loeches, I., Pirracchio, R., Legrand, M., Mainardi, J. L., Mantz, J., Cholley, B., Hubbard, A., Frontera, P. Ruiz, Vega, L. M. Claraco, Miguelena, P. Ruiz de Gopegui, Usón, M. C. Villuendas, López, A. Rezusta, Clemente, E. Aurensanz, Ibañes, P. Gutiérrez, Aguilar, A. L. Ruiz, Palomar, M., Olaechea, P., Uriona, S., Vallverdu, M., Catalan, M., Nuvials, X., Aragon, C., Lerma, F. Alvarez, Jeon, Y. D., Jeong, W. Y., Kim, M. H., Jeong, I. Y., Ahn, M. Y., Ahn, J. Y., Han, S. H., Choi, J. Y., Song, Y. G., Kim, J. M., Ku, N. S., Bassi, G. Li, Xiol, E. Aguilera, Senussi, T., Idone, F. A., Motos, A., Chiurazzi, C., Travierso, C., Fernández-Barat, L., Amaro, R., Hua, Y., Ranzani, O. T., Bobi, Q., Rigol, M., Torres, A., Fernández, I. Fuentes, Soler, E. Andreu, de Vera, A. Pareja Rodríguez, Pastor, E. Escudero, Hernandis, V., Ros Martínez, J., Rubio, R. Jara, Torner, M. Miralbés, Brugger, S. Carvalho, Eroles, A. Aragones, Moles, S. Iglesias, Cabello, J. Trujillano, Schoenenberger, J. A., Casals, X. Nuvials, Vidal, M. Vallverdu, Garrido, B. Balsera, Martinez, M. Palomar, Mirabella, L., Cotoia, A., Tullo, L., Stella, A., Di Bello, F., Di Gregorio, A., Dambrosio, M., Cinnella, G., Rosario, L. E. de la Cruz, Lesmes, S. P. Gómez, Romero, J. C. García, Herrera, A. N. García, Pertuz, E. D. Díaz, Sánchez, M. J. Gómez, Sanz, E. Regidor, Hualde, J. Barado, Hernández, A. Ansotegui, Ramirez, J. Roldán, Takahashi, H., Kazutoshi, F., Okada, Y., Oobayashi, W., Naito, T., Baidya, D. K., Maitra, S., Anand, R. K., Ray, B. R., Arora, M. K., Ruffini, C., Rota, L., Corona, A., Sesana, G., Ravasi, S., Catena, E., Naumann, D. N., Mellis, C., Husheer, S. L., Bishop, J., Midwinter, M. J., Hutchings, S., Corradi, F., Brusasco, C., Manca, T., Ramelli, A., Lattuada, M., Nicolini, F., Gherli, T., Vezzani, A., Young, A., Carmona, A. Fernández, Santiago, A. Iglesias, Guillamon, L. Navarro, Delgado, M. J. García, Delgado-Amaya, M., Curiel-Balsera, E., Rivera-Romero, L., Castillo-Lorente, E., Carrero-Gómez, F., Aguayo-DeHoyos, E., Healey, A. J., Cameron, C., Jiao, L.R., Stümpfle, R., Pérez, A., Martin, S., del Moral, O. Lopez, Toval, S., Rico, J., Aldecoa, C., Oguzhan, K., Demirkiran, O., Kirman, M., Bozbay, S., Kosuk, M. E., Asyralyyeva, G., Dilek, M., Duzgun, M., Telli, S., Aydin, M., Yilmazer, F., Hodgson, L. E., Dimitrov, B. D., Stubbs, C., Forni, L. G., Venn, R., Vedage, D., Shawaf, S., Naran, P., Sirisena, N., Kinnear, J., Dimitrov, B. D., Hodgson, L. E., Stubbs, C., Forni, L. G., Venn, R., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Ginés, A. Sánchez, Gubianas, C. Murcia, Sánchez, E. Clapes, Sirvent, J. M., Panafidina, V., Shlyk, I., Ilyina, V., Judickas, S., Kezyte, G., Urbanaviciute, I., Serpytis, M., Gaizauskas, E., Sipylaite, J., Sprung, C. L., Munteanu, G., Morales, R. C., Kasdan, H., Volker, T., Reiter, A., Cohen, Y., Himmel, Y., Meissonnier, J., Banderas-Bravo, M. E., Gómez-Jiménez, C., García-Martínez, M. V., Martínez-Carmona, J. F., Fernández-Ortega, J. F., O‘Dwyer, M. J., Starczewska, M., Wilks, M., Vincent, J. L., Torsvik, M., Gustad, L. T., Bangstad, I. L., Vinje, L. J., Damås, J. K., Solligård, E., Mehl, A., Tsunoda, M., Kang, M., Saito, M., Saito, N., Akizuki, N., Namiki, M., Takeda, M., Yuzawa, J., Yaguchi, A., Frantzeskaki, F., Tsirigotis, P., Chondropoulos, S., Paramythiotou, E., Theodorakopoulou, M., Stamouli, M., Gkirkas, K., Dimopoulou, I. K., Makiko, S., Tsunoda, M., Kang, M., Yuzawa, J., Akiduki, N., Namiki, M., Takeda, M., Yaguchi, A., Preau, S., Ambler, M., Sigurta, A., Saeed, S., Singer, M., Jochmans, S., Chelly, J., Vong, L. V. P., Sy, O., Serbource-Goguel, J., Rolin, N., Weyer, C. M., Abdallah, R. I., Adrie, C., Vinsonneau, C., Monchi, M., Mayr, U., Huber, W., Karsten, E., Lahmer, T., Thies, P., Henschel, B., Fischer, G., Schmid, R. M., Ediboglu, O., Ataman, S., Naz, I., Yaman, G., Kirakli, C., Su, P. L., Kou, P. S., Lin, W. C., Chen, C. W., Lozano, J. A. Benítez, Sánchez, P. Carmona, Francioni, J. E. Barrueco, Ferrón, F. Ruiz, Simón, J. M. Serrano, Riad, Z., Mezidi, M., Aublanc, M., Perinel, S., Lissonde, F., Louf-Durier, A., Yonis, H., Tapponnier, R., Richard, J. C., Louis, B., Guérin, C., Mezidi, M., Yonis, H., Aublanc, M., Lissonde, F., Louf-Durier, A., Perinel, S., Tapponnier, R., Richard, J. C., Guérin, C., Marmanidou, K., Oikonomou, M., Nouris, C., Loizou, C., Soilemezi, E., Matamis, D., Somhorst, P., Gommers, D., Hayashi, K., Hirayama, T., Yumoto, T., Tsukahara, K., Iida, A., Nosaka, N., Sato, K., Ugawa, T., Nakao, A., Ujike, Y., Hirohata, S., Mojoli, F., Torriglia, F., Giannantonio, M., Orlando, A., Bianzina, S., Tavazzi, G., Mongodi, S., Pozzi, M., Iotti, G. A., Braschi, A., Jansen, D., Gadgil, S., Doorduin, J., Roesthuis, L., van der Hoeven, J. G., Heunks, L. M. A., Chen, G. Q., Sun, X. M., He, X., Yang, Y. L., Shi, Z. H., Xu, M., Zhou, J. X., Pereira, S. M., Tucci, M. R., Tonelotto, B. F. F., Simoes, C. M., Morais, C. C. A., Pompeo, M. S., Kay, F. U., Amato, M. B. P., Vieira, J. E., Suzuki, S., Mihara, Y., Hikasa, Y., Okahara, S., Morimatsu, H., Kwon, H. M., Moon, Y. J., Lee, S. H., Jung, K. W., Shin, W. J., Jun, I. G., Song, J. G., Hwang, G. S., Lee, S., Moon, Y. J., Kwon, H. M., Jung, K., Shin, W. J., Jun, I. G., Song, J. G., Hwang, G. S., Ramelli, A., Manca, T., Corradi, F., Brusasco, C., Nicolini, F., Gherli, T., Brianti, R., Fanzaghi, P., Vezzani, A., Tudor, B. A., Klaus, D. A., Lebherz-Eichinger, D., Lechner, C., Schwarz, C., Bodingbauer, M., Seemann, R., Kaczirek, K., Fleischmann, E., Roth, G. A., Krenn, C. G., Malyshev, A., Sergey, S., Yamaguchi, Y., Nomura, T., Yoshitake, E., Idei, M., Yoshida, T., Takaki, S., Yamaguchi, O., Kaneko, M., Goto, T., Tencé, N., Zaien, I., Wolf, M., Trouiller, P., Jacobs, F. M., Kelly, J. M., Veigas, P., Hollands, S., Min, A., Rizoli, S., Robles, C. M. Coronado, de Oca Sandoval, M. A. Montes, Tarabrin, O., Gavrychenko, D., Mazurenko, G., Tarabrin, P., Garcia, I. Palacios, Martin, A. Diaz, Mendez, M. Casado, orden, V. Arellano, Noval, R. Leal, McCue, C., Gemmell, L., MacKay, A., Luján, J., Villa, P., Llorente, B., Molina, R., Alcázar, L., Juanas, C. Arenillas, Rogero, S., Pascual, T., Cambronero, J. A., Almudévar, P. Matía, Domínguez, J. Palamidessi, Carmona, S. Alcántara, Castañeda, D. Palacios, Abellán, A. Naharro, Lucendo, A. Pérez, Pérez, L. Pérez, Rivas, R. Fernández, Sanz, N. Martínez, Ramos, J. Veganzones, Villamizar, P. Rodríguez, Javadpour, S., Kalani, N., Amininejad, T., Jamali, S., Sobhanian, S., Laurent, A., Bonnet, M., Rigal, R., Aslanian, P., Hebert, P., Capellier, G., Contreras, M. R. Diaz, Mejías, C. Rodriguez, Ruiz, F. C. Santiago, Lombardo, M. Duro, Perez, J. Castaño, de Hoyos, E. Aguayo, Estella, A., Viciana, R., Fontaiña, L. Perez, Rico, T., Madueño, V. Perez, Recuerda, M., Fernández, L., Sandiumenge, A., Bonet, S., Mazo, C., Rubiera, M., Ruiz-Rodríguez, J. C., Gracia, R. M., Espinel, E., Pont, T., Kotsopoulos, A., Jansen, N., Abdo, W. F., Gopcevic, A., Gavranovic, Z., Vucic, M., Glogoski, M. Zlatic, Penavic, L. Videc, Horvat, A., Martin-Villen, L., Egea-Guerero, J. J., Revuelto-Rey, J., Aldabo-Pallas, T., Correa-Chamorro, E., Gallego-Corpa, A. I., Granados, P. Ruiz del Portal-Ruiz, Faivre, V., Wildenberg, L., Huot, B., Lukaszewicz, A. C., Simsir, M., Mengelle, C., Payen, D., Sanz, N. Martinez, Valbuena, B. Lobo, de la Fuente, M. Valdivia, Almudena, P. Matía, Pérez, L. Pérez, Carmona, S. Alcántara, Abellán, A. Navarro, Simón, I. Fernández, Muñoz, J. J. Rubio, Ramos, J. Veganzones, Carmona, S. Alcantara, Almudevar, P. Matia, Abellan, A. Naharro, Lucendo, M. A. Perez, Perez, L. Perez, Dominguez, J. Palamidessi, Rivas, R. Fernandez, Villamizar, P. Rodriguez, Wee, S., Ong, C., Lau, Y. H., Wong, Y., Banderas-Bravo, M. E., Olea-Jiménez, V., Mora-Ordóñez, J. M., Gómez-Jiménez, C., Muñoz-Muñoz, J. L., Vallejo-Báez, J., Daga-Ruiz, D., Lebrón-Gallardo, M., Rialp, G., Raurich, J. M., Morán, I., Martín, M. C., Heras, G., Mas, A., Vallverdú, I., Hraiech, S., Bourenne, J., Guervilly, C., Forel, J. M., Adda, M., Sylla, P., Mouaci, A., Gainnier, M., Papazian, L., Bauer, P. R., Kumbamu, A., Wilson, M. E., Pannu, J. K., Egginton, J. S., Kashyap, R., Gajic, O., Yoshihiro, S., Sakuraya, M., Hayakawa, M., Hirata, A., Kawamura, N., Tsutui, T., Yoshida, K., Hashimoto, Y., Chang, C. H., Hu, H. C., Chiu, L. C., Hung, C. Y., Li, S. H., Kao, K. C., Sibley, S., Drover, J., D’Arsigny, C., Parker, C., Howes, D., Moffatt, S., Erb, J., Ilan, R., Messenger, D., Ball, I., Boyd, J. G., Harrison, M., Ridi, S., Muscedere, J., Andrade, A. H., Costa, R. C., Souza, V. A., Gonzalez, V., Amorim, V., Rolla, F., Filho, C. A. C. Abreu, Miranda, R., Atchasiri, S., Buranavanich, P., Wathanawatthu, T., Suwanpasu, S., Bureau, C., Rolland-Debord, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Diaz, P., Nunes, J., Escórcio, S., Silva, G., Chaves, S., Jardim, M., Câmara, M., Fernandes, N., Duarte, R., Jardim, J. J., Pereira, C. A., Nóbrega, J. J., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Lee, S. J., Cha, Y. S., Lee, W. Y., Onodera, M., Nakataki, E., Oto, J., Imanaka, H., Nishimura, M., Khadjibaev, A., Sabirov, D., Rosstalnaya, A., Akalaev, R., Parpibaev, F., Antonucci, E., Rossini, P., Gandolfi, S., Montini, E., Orlando, S., van Nes, M., Karachi, F., Hanekom, S., Andrade, A. H., Pereira, U. V., Filho, C. A. C. Abreu, Costa, R. C., Parkin, M. S. W., Moore, M., Andrade, A. H., Costa, R. C., Carvalho, K. V. Silva, Filho, C. A. C. Abreu, Min, H. J., Kim, H. J., Lee, D. S., Choi, Y. Y., Lee, E. Y., Song, I., Kim, D. J., E, Y. Y., Kim, J. W., Park, J. S., Cho, Y. J., Lee, J. H., Suh, J. W., Jo, Y. H., Kim, K. S., Lee, Y. J., Ferrero-Calleja, J., Merino-Vega, D., González-Jiménez, A. I., Sigcha, M. Sigcha, Hernández-Tejedor, A., Martin-Vivas, A., Gabán-Díez, Á., Luna, R. Ruiz-de, De la Calle-Pedrosa, N., Temprano-Gómez, I., Afonso-Rivero, D., Pellin-Ariño, J. I., Algora-Weber, A., Fumis, R. R. L., Ferraz, A. B., Junior, J. M. Vieira, Kirca, H., Cakin, O., Unal, M., Mutlu, H., Ramazanoglu, A., Cengiz, M., Nicolini, E. A., Pelisson, F. G. F., Nunes, R. S., da Silva, S. L., Carreira, M. M., Bellissimo-Rodrigues, F., Ferez, M. A., Basile-Filho, A., Chao, H. C., Chen, C. M., Chen, L., Hravnak, M., Clermont, G., Pinsky, M., Dubrawski, A., Varas, J. Luján, Montero, R. Molina, Sánchez-Elvira, L. Alcázar, Díaz, P. Villa, Delgado, C. Pintado, Ruiz, B. Llorente, Guerrero, A. Pardo, Galache, J. A. Cambronero, Sherif, H., Hassanin, H., El Hossainy, R., Samy, W., Ly, H., David, H., Burtin, P., Charpentier, C., Barral, M., Courant, P., Fournel, E., Gaide-Chevronnay, L., Durand, M., Albaladejo, P., Payen, J. F., Chavanon, O., Ortiz, A. Blandino, Pozzebon, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Fumagalli, F., Scala, S., Affatato, R., De Maglie, M., Zani, D., Novelli, D., Marra, C., Luciani, A., De Zani, D., Luini, M., Letizia, T., Pravettoni, D., Staszewsky, L., Masson, S., Belloli, A., Di Giancamillo, M., Scanziani, E., Latini, R., Ristagno, G., Kye, Y. C., Suh, G. J., Kwon, W. Y., Kim, K. S., Yu, K. M., Babini, G., Ristagno, G., Grassi, L., Fumagalli, F., Bendel, S., De Maglie, M., Affatato, R., Masson, S., Latini, R., Scanziani, E., Reinikainen, M., Skrifvars, M., Kappler, F., Blobner, M., Schaller, S. J., Roasio, A., Costanzo, E., Cardellino, S., Iesu, E., Cavicchi, F. Zama, Fontana, V., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Park, M., You, K. M., Suh, G. J., Kwon, W. Y., Ko, S. B., Kim, K. S., Xini, A., Marca, L., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Beane, A., Thilakasiri, M. C. K. T., De Silva, A. P., Stephens, T., Sigera, C. S., Athapattu, P., Jayasinghe, S., Padeniya, A., Haniffa, R., Santiago, A. Iglesias, Sáez, V. Chica, Ruiz-Ruano, R. de la Chica, González, A. Sánchez, Kunze-Szikszay, N., Wand, S., Klapsing, P., Wetz, A., Heyne, T., Schwerdtfeger, K., Troeltzsch, M., Bauer, M., Quintel, M., Moerer, O., Cook, D. J., Rutherford, W. B., Scales, D. C., Adhikari, N. K., Cuthbertson, B. H., Suzuki, T., Takei, T., Fushimi, K., Iwamoto, M., Nakagawa, S., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M. W., Romero, D. González, Cabrera, J. L. Santana, Santana, J. D. Martín, Padilla, Y. Santana, Pérez, H. Rodríguez, Torrent, R. Lorenzo, Kleinpell, R., Chouris, I., Radu, V., Stougianni, M., Lavrentieva, A., Lagonidis, D., Price, R. D. T., Day, A., Arora, N., Henderson, M. A., Hickey, S., Costa, M. I. Almeida, Carvalho, J. P., Gomes, A. A., Mergulhão, P. J., Chan, K. K. C., Shum, H. P., Yan, W. W., Maghsoudi, B., Tabei, S. H., Masjedi, M., Sabetian, G., Tabatabaei, H. R., Akbarzadeh, A., Saigal, S., Pakhare, A., Joshi, R., Pattnaik, S. K., Ray, B., Rousseau, A. F., Michel, L., Bawin, M., Cavalier, E., Reginster, J. Y., Damas, P., Bruyere, O., Zhou, J. C., Cauwenberghs, H., De Backer, A., Neels, H., Deblier, I., Berghmans, J., Himpe, D., Barea-Mendoza, J. A., Portillo, I. Prieto, Fernández, M. Valiente, Gigorro, R. Garcia, Vela, J. L. Perez, Mateos, H. Marín, Alves, S. Chacón, Varas, G. Morales, Rodriguez-Biendicho, A., Carreño, E. Renes, González, J. C. Montejo, Yang, J. S., Chiang, C. H., Hung, W. T., Huang, W. C., Cheng, C. C., Lin, K. C., Lin, S. C., Chiou, K. R., Wann, S. R., Lin, K. L., Kang, P. L., Mar, G. Y., Liu, C. P., Zhou, J. C., Choi, Y. J., Yoon, S. Z., Gordillo-Brenes, A., Fernandez-Zamora, M. D., Perez-Borrero, L., Arias-Verdu, M. D., Aguilar-Alonso, E., Herruzo-Aviles, A., Garcia-Delgado, M., Hinojosa-Perez, R., Curiel-Balsera, E., Rivera-Fernandez, R., Lesmes, S. P. Gómez, Rosario, L. E. De la Cruz, Hernández, A. Ansotegui, Herrera, A. N. García, Sanz, E. Regidor, Sánchez, M. J. Gómez, Hualde, J. Barado, Pascual, O. Agudo, León, J. P. Tirapu, Irazabal, J. M. Guergue, Pérez, A. González, Fernández, P. Alvarez, Amor, L. Lopéz, Albaiceta, G. Muñiz, Lesmes, S. P. Gómez, Rosario, L. E. De la Cruz, Hernández, A. Ansotegui, Sanz, E. Regidor, Sánchez, M. J. Gómez, Calvo, S. Aldunate, Herrera, A. N. García, Hualde, J. Barado, Pascual, O. Agudo, León, J. P. Tirapu, Corona, A., Ruffini, C., Spazzadeschi, A., Marrazzo, F., Gandola, A., Sciurti, R., Savi, C., Catena, E., Ke, M. W., Cheng, C. C., Huang, W. C., Chiang, C. H., Hung, W. T., Lin, K. C., Lin, S. C., Wann, S. R., Chiou, K. R., Tseng, C. J., Kang, P. L., Mar, G. Y., Liu, C. P., Bertini, P., De Sanctis, F., Guarracino, F., Bertini, P., Baldassarri, R., Guarracino, F., Buitinck, S. H., van der Voort, P. H. J., Oto, J., Nakataki, E., Tsunano, Y., Izawa, M., Tane, N., Onodera, M., Nishimura, M., Ghosh, S., Gupta, A., De Gasperi, A., Mazza, E., Limuti, R., Prosperi, M., Bissenova, N., Yergaliyeva, A., Talan, L., Yılmaz, G., Güven, G., Yoruk, F., Altıntas, N. D., Mukherjee, D. N., Agarwal, L. K., Mandal, K., Palomar, M., Balsera, B., Vallverdu, M., Martinez, M., Garcia, M., Castellana, D., Lopez, R., Barcenilla, F., Kaminsky, G. E., Carreño, R., Escribá, A., Fuentes, M., Gálvez, V., Del Olmo, R., Nieto, B., Vaquerizo, C., Alvarez, J., De la Torre, M. A., Torres, E., Bogossian, E., Nouer, S. Aranha, Salgado, D. Ribeiro, Brugger, S. Carvalho, Jiménez, G. Jiménez, Torner, M. Miralbés, Vidal, M. Vallverdú, Garrido, B. Balsera, Casals, X. Nuvials, Gaite, F. Barcenilla, Cabello, J. Trujillano, Martínez, M. Palomar, Doganci, M., Izdes, S., Besevli, S. Guzeldag, Alkan, A., Kayaaslan, B., Ramírez, C. Sánchez, Balcázar, L. Caipe, Santana, M. Cabrera, Viera, M. A. Hernández, Escalada, S. Hípola, Vázquez, C. F. Lübbe, Penichet, S. M. Marrero, Campelo, F. Artiles, López, M. A. De La Cal, Santana, P. Saavedra, Santana, S. Ruíz, Repessé, X., Artiguenave, M., Paktoris-Papine, S., Espinasse, F., Dinh, A., El Sayed, F., Charron, C., Géri, G., Vieillard-Baron, A., Marmanidou, K., Oikonomou, M., Nouris, C., Dimitroulakis, K., Soilemezi, E., Matamis, D., Ferré, A., Guillot, M., Teboul, J. L., Lichtenstein, D., Mézière, G., Richard, C., Monnet, X., Pham, T., Beduneau, G., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, P. G., Frat, J. P., Constan, A., Chrétien, J. M., Mancebo, J., Mercat, A., Richard, J. C. M., Brochard, L., Prīdāne, S., Sabeļņikovs, O., Mojoli, F., Orlando, A., Bianchi, I., Torriglia, F., Bianzina, S., Pozzi, M., Iotti, G. A., Braschi, A., Beduneau, G., Pham, T., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, P. G., Frat, J. P., Constan, A., Chrétien, J. M., Mancebo, J., Mercat, A., Richard, J. C. M., Brochard, L., Kondili, E., Psarologakis, C., Kokkini, S., Amargianitakis, V., Babalis, D., Chytas, A., Chouvarda, I., Vaporidi, K., Georgopoulos, D., Trapp, O., Kalenka, A., Mojoli, F., Orlando, A., Bianchi, I., Torriglia, F., Bianzina, S., Pozzi, M., Iotti, G. A., Braschi, A., Lozano, J. A. Benítez, Sánchez, P. Carmona, Francioni, J. E. Barrueco, Ferrón, F. Ruiz, Simón, J. M. Serrano, Spadaro, S., Karbing, D. S., Gioia, A., Moro, F., Corte, F. Dalla, Mauri, T., Volta, C. A., Rees, S. E., Petrova, M. V., Mohan, R., Butrov, A. V., Beeharry, S. D., Vatsik, M. V., Sakieva, F. I., Gobert, F., Yonis, H., Tapponnier, R., Fernandez, R., Labaune, M. A., Burle, J. F., Barbier, J., Vincent, B., Cleyet, M., Richard, J. C., Guérin, C., Shinotsuka, C. Righy, Creteur, J., Taccone, F. S., Törnblom, S., Nisula, S., Vaara, S., Poukkanen, M., Andersson, S., Pettilä, V., Pesonen, E., Xie, Z., Liao, X., Kang, Y., Zhang, J., Kubota, K., Egi, M., Mizobuchi, S., Hegazy, S., El-Keraie, A., El Sayed, E., El Hamid, M. Abd, Rodrigues, N. J., Pereira, M., Godinho, I., Gameiro, J., Neves, M., Gouveia, J., e Silva, Z. Costa, Lopes, J. A., Mckinlay, J., Kostalas, M., Kooner, G., Dudas, G., Horton, A., Kerr, C., Karanjia, N., Creagh-Brown, B., Forni, L., Yamazaki, A., Ganuza, M. Sanz, Molina, J. A. Martinez, Martinez, F. Hidalgo, Freile, M. T. Chiquito, Fernandez, N. Garcia, Travieso, P. Medrano, Bandert, A., Frithiof, R., Lipcsey, M., Smekal, D., Schlaepfer, P., Durovray, J. D., Plouhinec, V., Chiappa, C., Bellomo, R., Schneider, A. G., Mitchell, S., Durrant, J., Street, H., Dunthorne, E., Shears, J., Caballero, C. Hernandez, Hutchison, R., Schwarze, S., Ghabina, S., Thompson, E., Prowle, J. R., Kirwan, C. J., Gonzalez, C. A., Pinto, J. L., Orozco, V., Patiño, J. A., Garcia, P. K., Contreras, K. M., Rodriguez, P., Echeverri, J. E., GETGAG Working Group, JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group, CAPCRI Study, for the ReVA Research Network and the PROVE Network Investigators, from the FROG ICU Investigators, The WIND study group, Plug Working Group, GETGAG/SEMICYUC, AKI Research Group, St George’s University of London, IPREA Study Group, FINNRESUSCI Study Group, PICS- HCPA: Programa Intrahospitalar de Combate à Sepse do Hospital de Clínicas de Porto Alegre, ENVIN-HELICS Study Group, ARIAM registry of adult cardiac surgery, The Rapid Diagnosis of Infections in the Critically Ill Team, Tokyo Womens Medical University, PLUG working group, PLUG Working Group, On behalf of Okayama Research Investigation Organizing Network (ORION)investigators, PS-ICU Group, Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group, Student Research Committee - Shiraz University of Medical Sciences, ARIAM-ANDALUCIA, The WIND study group, PLUG Working Group, The WIND study group, PLUG Working Group, and Plug working group more...
Published: 2016
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2. ESICM LIVES 2016: part two: Milan, Italy. 1–5 October 2016

Author: Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Lazaridis, C., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, D. E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., van den Boogaard, M., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Moore, J., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Randall, D., Adwaney, A., Blunden, M., Prowle, J.R., Kirwan, C. J., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., Girbes, A. R. J., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Carteron, L., Patet, C., Quintard, H., Solari, D., Bouzat, P., Oddo, M., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schneider, J., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Vincent, J. L., Creteur, J., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. J., Fortuit, C., Feuillet, F., Asehnoune, K., Marzorati, C., Spina, S., Scaravilli, V., Vargiolu, A., Riva, M., Giussani, C., Sganzerla, E., Citerio, G., Barbadillo, S., de Molina, F. J. González, Álvarez-Lerma, F., Rodríguez, A., Zakharkina, T., Martin-Loeches, I., Matamoros, S., Povoa, P., Torres, A., Kastelijn, J., Hofstra, J. J., de Jong, M., Schultz, M., Sterk, P., Artigas, A., Bos, L. J., Moreau, A. S., Martin-Loeches, I., Povoa, P., Salluh, J., Rodriguez, A., Nseir, S., de Jong, E., van Oers, J. A., Beishuizen, A., Girbes, A. R. J., Nijsten, M. W. N., de Lange, D. W., Bonvicini, D., Labate, D., Benacchio, L., Olivieri, A., Pizzirani, E., Lopez-Delgado, J. C., Gonzalez-Romero, M., Fuentes-Mila, V., Berbel-Franco, D., Romera-Peregrina, I., Martinez-Pascual, A., Perez-Sanchez, J., Abellan-Lencina, R., Ávila-Espinoza, R. E., Moreno-Gonzalez, G., Sbraga, F., Griffiths, S., Grocott, M. P. W., Creagh-Brown, B., Doyle, J., Wilkerson, P., Soon, Y., Huddart, S., Dickinson, M., Riga, A., Zuleika, A., Miyamoto, K., Kawazoe, Y., Morimoto, T., Yamamoto, T., Fuke, A., Hashimoto, A., Koami, H., Beppu, S., Katayama, Y., Ito, M., Ohta, Y., Yamamura, H., Rygård, S. L., Holst, L B., Wetterslev, J., Johansson, P. I., Perner, A., Soliman, I. W., de Lange, D. W., van Dijk, D., van Delden, J. J. M., Cremer, O. L., Slooter, A. J. C., Peelen, L. M., McWilliams, D., Snelson, C., Neves, A. Das, Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Veronesi, M., Lischinsky, A., López, F. J. L., Mori, L. Benito, Plotnikow, G., Díaz, A., Giannasi, S., Hernandez, R., Krzisnik, L., Cecotti, C., Viola, L., Lopez, R., Sottile, J. P., Benavent, G., Estenssoro, E., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Chan, K. S., Roeker, L. E., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Weijs, P. J. M., Mogensen, K. M., Rawn, J. D., Robinson, M. K., Christopher, K. B., Tang, Z., Qiu, C., Ouyang, B., Cai, C., Guan, X., Regueira, T., Cea, L., Carlos, S. Juan, Elisa, B., Puebla, C., Vargas, A., Poulsen, M. K., Thomsen, L. P., Kjærgaard, S., Rees, S. E., Karbing, D. S., Wollersheim, T., Frank, S., Müller, M. C., Carbon, N. M., Skrypnikov, V., Pickerodt, P. A., Falk, R., Mahlau, A., Weber-Carstens, S., Lee, A., Inglis, R., Morgan, R., Barker, G., Kamata, K., Abe, T., Saitoh, D., Tokuda, Y., Green, R. S., Butler, M. B., Erdogan, M., Hwa, H. Tae, Gil, L. Jae, Vaquero, R. Hernández, Rodriguez-Ruiz, E., Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Thomas-Rüddel, D. O., Schwarzkopf, D., Fleischmann, C., Reinhart, K., Suwanpasu, S., Sattayasomboon, Y., Filho, N. M. Filgueiras, Oliveira, J. C. A., Ballalai, C. S., De Lucia, C. V., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Ramos, B. B., Ricaldi, E. F., Gomes, S. S., Gemmell, L., MacKay, A., Wright, C., Docking, R. I., Doherty, P., Black, E., Stenhouse, P., Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Yatabe, T., Inoue, S., Sakaguchi, M., Egi, M., Abdelhamid, Y. Ali, Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Hokka, M., Egi, M., Mizobuchi, S., Kar, P., Plummer, M., Abdelhamid, Y. Ali, Giersch, E., Summers, M., Hatzinikolas, S., Heller, S., Chapman, M., Jones, K., Horowitz, M., Deane, A., Schweizer, R., Jacquet-Lagreze, M., Portran, P., Junot, S., Allaouchiche, B., Fellahi, J. L., Guerci, P., Ergin, B., Kapucu, A., Ince, C., Cioccari, L., Luethi, N., Crisman, M., Bellomo, R., Mårtensson, J., Shinotsuka, C. Righy, Fagnoul, D., Brasseur, A., Orbegozo, D., Vincent, J. L., Preiser, J. C., Preiser, J. C., Lheureux, O., Thooft, A., Brimioulle, S., Vincent, J. L., Iwasaka, H., Tahara, S., Nagamine, M., Ichigatani, A., Cabrera, A. Rugerio, Zepeda, E. Monares, Granillo, J. Franco, Sánchez, J. S. Aguirre, Montoya, A. A. Tanaka, Montenegro, A. Pedraza, Blanco, G. A. Gálvez, Robles, C. M. Coronado, Drolz, A., Horvatits, T., Roedl, K., Rutter, K., Kluge, S., Funk, G. C., Schneeweiss, B., Fuhrmann, V., Sabetian, G., Pooresmaeel, F., Zand, F., Ghaffaripour, S., Farbod, A., Tabei, H., Taheri, L., Anandanadesan, R., Metaxa, V., Teixeira, C., Pereira, S. M., Hernández-Marrero, P., Carvalho, A. S., Beckmann, M., Hartog, C. S., Schwarzkopf, D., Raadts, A., Robertsen, A., Førde, R., Skaga, N. O., Helseth, E., Honeybul, S., Ho, K., Lopez, P. Martinez, Gonzalez, M. Nieto, Ortega, P. Nuevo, Sola, E. Camara, Spasova, T., de la Torre-Prados, M. V., Kopecky, O., Rusinova, K., Waldauf, P., Cepeplikova, Z., Balik, M., Domínguez, J. Palamidessi, Almudevar, P. Matia, Carmona, S. Alcántara, Muñoz, J. J. Rubio, Castañeda, D. Palacios, Abellán, A. Naharro, Villamizar, P. Rodríguez, Ramos, J. Veganzones, Pérez, L. Pérez, Lucendo, A. Pérez, Ejarque, M. Camós, Estella, A., Camps, V. Lopez, Martín, M. C., Masnou, N., Barbosa, S., Varela, A., Palma, I., Cristina, L., Nunes, E., Pereira, I., Campello, G., Granja, C., Pande, R., Pandey, M., Varghese, S., Chanu, M., Van Dam, M. J., Ter Braak, E. W. M. T., Estella, A., Gracia, M., Viciana, R., Recuerda, M., Fontaiña, L. Perez, Tharmalingam, B., Kovari, F., Rose, L., Mcginlay, M., Amin, R., Burns, K., Connolly, B., Hart, N., Jouvet, P., Katz, S., Leasa, D., Mawdsley, C., Mcauley, D., Schultz, M., Blackwood, B., Denham, S., Worrall, R., Arshad, M., Isherwood, P., Khadjibaev, A., Sabirov, D., Rosstalnaya, A., Parpibaev, F., Sharipova, V., Blanco, G. A. Galvez, Guzman, C. I. Olvera, Sánchez, J. S. Aguirre, Granillo, J. Franco, Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Shafi, M., Tomar, D. S., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Cha, Y. S., Lee, S. J., Tyagi, N., Rajput, R. K., Taneja, S., Singh, V. K., Sharma, S. C., Mittal, S., Rao, B. K., Ayachi, J., Fraj, N., Romdhani, S., Khedher, A., Meddeb, K., Sma, N., Azouzi, A., Bouneb, R., Chouchene, I., El Ghardallou, M., Boussarsar, M., Jennings, R., Walter, E., Ribeiro, J. M., Moniz, I., Marçal, R., Santos, A. C., Candeias, C., e Silva, Z. Costa, Gomez, S. E. Zamora, Nieto, O. R. Perez, Gonzalez, J. A. Castanon, Cuellar, A. I. Vasquez, Mildh, H., Pettilä, V., Korhonen, A. M., Karlsson, S., Ala-Kokko, T., Reinikainen, M., Vaara, S. T., Zaleska-Kociecka, M., Grabowski, M., Dąbrowski, M., Wozniak, S., Piotrowska, K., Banaszewski, M., Imiela, J., Stepinska, J., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Koeze, J., Keus, F., Dieperink, W., van der Horst, I. C. C., van Meurs, M., Zijlstra, J. G., Roberts, S., Caballero, C. Hernandez, Isgro, G., Hall, D., Beitland, S., Trøseid, A.-M. S., Brusletto, B. S., Waldum-Grevbo, B. E., Berg, J. P., Sunde, K., Huertas, D. García, Manzano, F., Quintana, M. M. Jiménez-, Osuna, A., Santiago-Ruiz, F., Rodríguez-Mejías, C., Wangensteen, R., Jamaati, H. R., Masjedi, M., Zand, F., Hashemian, S. M. R., Sabetian, G., Abbasi, G., Khaloo, V., Tabei, S. H.a., Kafilzadeh, A., Bakhodaei, H. Haddad, Diaz, J. A., Silva, R., Garcia, D. J., Luis, E., Gomez, M. N., Soriano, R., Gonzalez, P. L., Ibrahim, I. A., Rafik, M. M., Al-Ansary, A. M., Algendi, M. A., Ali, A. A., Fuhrmann, V., Roedl, K., Horvatits, T., Drolz, A., Rutter, K., Benten, D., Kluwe, J., Siedler, S., Kluge, S., Adedugbe, I., Bird, G. T., Kennedy, R. M., Sharma, S., Butler, M. B., Yugi, G., Haroon, B. A., Witter, T., Khaliq, W., Singer, M., Havaldar, A. A., Krishna, B., Sriram, S., Espinoza, E. D. Valenzuela, Pozo, M. O., Edul, V. S. Kanoore, Furche, M., Motta, M. F., Vazquez, A. Risso, Birri, P. N. Rubatto, Ince, C., Dubin, A., Dogliotti, A., Ramos, A., Lovesio, C., Delile, E., Nevière, R., Thiébaut, P.-A., Maupoint, J., Mulder, P., Coquerel, D., Renet, S., do Rego, J. C., Rieusset, J., Richard, V., Tamion, F., Khaliq, W., Andreis, D. T., Singer, M., Smit, B., Smulders, Y. M., de Waard, M. C., van Straaten, H. M. Oudemans, Girbes, A. R. J., Eringa, E. C., Man, A. M. E. Spoelstra-de, Alegría, L., Soto, D., Luengo, C., Gomez, J., Jarufe, N., Bruhn, A., Castro, R., Kattan, E., Tapia, P., Rebolledo, R., Achurra, P., Ospina-Tascón, G., Bakker, J., Hernández, G., Bertini, P., Guarracino, F., Baldassarri, R., Pinsky, M. R., Alegría, L., Vera, M., Dreyse, J., Carpio, D., Henriquez, C., Gajardo, D., Bravo, S., Castro, R., Ospina-Tascón, G., Bakker, J., Hernández, G., Kim, S., Lee, M., Park, S. Y., So, S., Lee, H., Kačar, M. B., Kačar, S. M., Uddin, I., Belhaj, A. M., Aydın, M. A., Avsec, D., Kapuağası, A., Kaymak, Ç., Kovach, L., Şencan, İ., Meço, B., Özçelik, M., Ünal, N., Lazaridis, C., Jenni-Moser, B., Jeitziner, M.-M., Galassi, M. S., Sales, F. L., de Moraes, K. C. L., Batista, C. L., Júnior, J. A. de Souza, Marcari, T. B., Lobato, R., Castro, C. S. A. A., de Souza, L. M., Rodrigues, F. F. P., Correa, N. G., Pelegrini, A. M., Eid, R. A. C., Timenetsky, K. T., Cazati, D., Lobato, M., Diniz, P. S., Rocha, L. L., Cavalheiro, A. M., Lucinio, N. M., Santos, E. R., Norrenberg, M., Gleize, A., Preiser, J. C., Simón, I. Fernández, Carmona, S. Alcántara, Valhonrat, I. Lipperheide, Domínguez, J. Palamidessi, Abellán, A. Naharro, Almudévar, P. Matía, Dávila, F., Rubio, J. J., Ramos, A. J., Reina, Á. J. Roldán, López, N. Palomo, Pérez, M. Adriaensens, Apolo, D. X. Cuenca, Villén, L. Martín, López, F. M. Porras, García, I. Palacios, Izurieta, J. R. Naranjo, Guerrero, J. J. Egea, Calvert, S., Quint, M., Adeniji, K., Young, R., Shevill, D. D., Robertson, E., Garside, P., Walter, E., Isotti, P., De Vecchi, M. M., Perduca, A. E., Negro, A., Villa, G., Manara, D. F., Cabrini, L., Zangrillo, A., Frencken, J. F., van Baal, L., Peelen, L. M., Donker, D. W., Horn, J., van der Poll, T., van Klei, W. A., Bonten, M. J. M., Cremer, O. L., Menard, C. E., Kumar, A., Rimmer, E., Doucette, S., Turgeon, A. F., Houston, B. L., Houston, D. S., Zarychanski, R., Pinto, B. Bollen, Carrara, M., Ferrario, M., Bendjelid, K., Nunes, J., Diaz, P., Silva, G., Escórcio, S., Chaves, S., Jardim, M., Fernandes, N., Câmara, M., Duarte, R., Pereira, C. A., Vieira, J., Nóbrega, J. J., Robles, C. M. Coronado, de Oca-Sandoval, M. A. Montes, Sánchez-Rodríguez, A., Joya-Galeana, J. G., Correa-Morales, A., Camarena-Alejo, G., Aguirre-Sánchez, J., Franco-Granillo, J., Soliman, M., Al Azab, A., El Hossainy, R., Nagy, H., Nirmalan, M., Crippa, I. A., Cavicchi, F. Zama, Vincent, J. L., Creteur, J., Taccone, F. S., Chaari, A., Hakim, K. Abdel, Hassanein, H., Etman, M., El Bahr, M., Bousselmi, K., Khalil, E. S., Kauts, V., Casey, W. F., Imahase, H., Sakamoto, Y., Inoue, S., Yamada, K. C., Koami, H., Miike, T., Nagashima, F., Iwamura, T., Boscolo, A., Lucchetta, V., Piasentini, E., Bertini, D., Manesso, L., Spiezia, L., Simioni, P., Ori, C., Souza, R. B., Martins, A. M., Liberatore, A. M. A., Kang, Y. R., Nakamae, M. N., Vieira, J. C. F., Koh, I. H. J., Hanslin, K., Wilske, F., Skorup, P., Sjölin, J., Lipcsey, M., Long, W. Jin, Zhen, C. Er, Vakalos, A., Avramidis, V., Wu, S. H., Shyu, L. J., Li, C. H., Yu, C. H., Chen, H. C., Wang, C. H., Lin, K. H., Aray, Z. E., Gómez, C. F., Tejero, A. P., Monge, D. D., Losada, V. M., Tarancón, C. M., Cortés, S. D., Gutiérrez, A. M., Álvarez, T. P., Rouze, A., Jaffal, K., Six, S., Stolz, K., Cattoen, V., Nseir, S., Arnal, J. M., Saoli, M., Novotni, D., Garnero, A., Becher, T., Buchholz, V., Schädler, D., Frerichs, I., Weiler, N., Eronia, N., Mauri, T., Gatti, S., Maffezzini, E., Bronco, A., Alban, L., Sasso, T., Marenghi, C., Grasselli, G., Pesenti, A., Bellani, G., Al-Fares, A., Del Sorbo, L., Anwar, S., Facchin, F., Azad, S., Zamel, R., Ferguson, N., Cypel, M., Keshavjee, S., Fan, E., Durlinger, E., Spoelstra-de Man, A., Smit, B., de Grooth, H. J., Girbes, A., Straaten, H. Oudemans-van, Smulders, Y., Alfaro, M. A., Parrilla, F., Meli, A., Pellegrini, M., Rodriguez, N., Goyeneche, J. M., Morán, I., Aguirre, H., Mancebo, J., Heines, S. J. H., Strauch, U., Bergmans, D. C. J. J., Blankman, P., Shono, A., Hasan, D., Gommers, D., Chung, W. Y., Lee, K. S., Jung, Y. J., Park, J. H., Sheen, S. S., Park, K. J., Worral, R., Denham, S., Isherwood, P., Rees, S. E., Larraza, S., Dey, N., Spadaro, S., Brohus, J. B., Winding, R. W., Volta, C. A., Karbing, D. S., Ampatzidou, F., Vlachou, A., Kehagioglou, G., Karaiskos, T., Madesis, A., Mauromanolis, C., Michail, N., Drossos, G., Saraj, N., Rijkenberg, S., Feijen, H. M., Endeman, H., Donnelly, A. A. J., Morgan, E., Garrard, H., Buckley, H., Russell, L., Haase, N., Perner, A., Goh, C., Mouyis, K., Woodward, C. L. N., Halliday, J., Encina, G. B., Ros, J., Lagunes, L., Tabernero, J., Bosch, F., Rello, J., Huertas, D. García, Manzano, F., Morente-Constantin, E., Rivera-Ginés, B., Colmenero-Ruiz, M., Abellán, A. Naharro, Pérez, L. Pérez, Lucendo, A. Pérez, Almudévar, P. Matía, Domínguez, J. Palamidessi, Villamizar, P. Rodríguez, Sanz, J. García, Simon, I. Fernandez, Valbuena, B. Lobo, Carmona, S. Alcantara, Pais, M., Ramalingam, S., Díaz, C., Fox, L., Santafe, M., Barba, P., García, M., Leal, S., Pérez, M., Pérez, M. L. Pérez, Abellán, A. Naharro, Lucendo, A. Pérez, Almudevar, P. Matia, Domínguez, J. Palamidessi, Villamizar, P. Rodríguez, Veganzones, J., Simón, I. Fernandez, Valbuena, B. Lobo, Martínez, N., Carmona, S. Alcántara, Moors, I., Mokart, D., Pène, F., Lambert, J., Kouatchet, A., Mayaux, J., Vincent, F., Nyunga, M., Bruneel, F., Laisne, L., Rabbat, A., Lebert, C., Perez, P., Chaize, M., Renault, A., Meert, A. P., Hamidfar, R., Jourdain, M., Darmon, M., Schlemmer, B., Chevret, S., Lemiale, V., Azoulay, E., Benoit, D., Martins-Branco, D., Sousa, M., Marum, S., Bouw, M. J., Galstyan, G., Makarova, P., Parovichnikova, E., Kuzmina, L., Troitskaya, V., Drize, N., Gemdzhian, E., Savchenko, V., Chao, H. C., Kılıc, E., Demiriz, B., Uygur, M. L., Sürücü, M., Cınar, K., Yıldırım, A. E., Kiss, K., Köves, B., Csernus, V., Molnár, Z., Ntantana, A., Matamis, D., Savvidou, S., Giannakou, M., Gouva, M., Nakos, G., Koulouras, V., Gaffney, S., Black, E., Docking, R., Judge, C., Drew, T., Misran, H., Munshi, R., McGovern, L., Coyle, M., Dunne, L., Deasy, E., Lavin, P., Fahy, A., Darcy, D. M., Donnelly, M., Ismail, N. H., Hall, T., Wykes, K., Jack, J., Ngu, W. C., Morgan, P., Ruiz-Ramos, J., Ramirez, P., Gordon, M., Villarreal, E., Frasquet, J., Poveda-Andrés, J. L., Castellanos, A., Ijssennagger, C. E., ten Hoorn, S., van Wijk, A., van den Broek, J. M., Tuinman, P. R., Elmenshawy, A. M., Hammond, B. D., Gibbon, G., Belcham, T., Burton, K., Taniguchi, L. U., Ramos, F. J. S., Momma, A. K., Martins-Filho, A. P. R., Bartocci, J. J., Lopes, M. F. D., Sad, M. H., Rodrigues, C. M., Pires, E. M. C., Vieira, Jr, J. M., Leite, M. A., Murbach, L. D., Osaku, E. F., Barreto, J., Duarte, S. T., Taba, S., Miglioranza, D., Gund, D. P., Lordani, C. F., Costa, C. R. L. M., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Spadaro, S., Capuzzo, M., Corte, F. Dalla, Terranova, S., Scaramuzzo, G., Fogagnolo, A., Bertacchini, S., Bellonzi, A., Ragazzi, R., Volta, C. A., Cruz, C., Nunes, A., Pereira, F. Seabra, Aragão, I., Cardoso, A. F., Santos, C., Malheiro, M. J., Castro, H., Cardoso, T., Paratz, J., Kenardy, J., Comans, T., Coyer, F., Thomas, P., Boots, R., Pereira, N., Vilas-Boas, A., Gomes, E., Dias, C., Torres, J., Carvalho, D., Molinos, E., Vales, C., Araújo, R., Cruz, C., Nunes, A., Pereira, F. Seabra, Cardoso, A. F., Santos, C., Malheiro, M. J., Castro, H., Cardoso, T., Karnatovskaia, L., Philbrick, K., Ognjen, G., Clark, M., Montero, R. Molina, Varas, J. Luján, Sánchez-Elvira, L. Alcázar, Delgado, C. Pintado, Díaz, P. Villa, Ruiz, B. Llorente, Guerrero, A. Pardo, Galache, J. A. Cambronero, Jiménez, R., Rebollo, S., Alejandro, O., Fernández, A., Moreno, S., Herrera, L., Ojados, A., Galindo, M., Murcia, J., Contreras, M., Sánchez-Argente, S., Bonilla, Y., Rodríguez, M. D., Allegue, J. M., Cakin, Ö., Parlak, H., Kirca, H., Mutlu, F., Aydınlı, B., Cengiz, M., Ramazanoglu, A., Jung, E.-J., Oh, S.-Y., Lee, H., Filho, N. M. Filgueiras, Ricaldi, E. F., Gomes, S. S., Ramos, B. B., De Lucia, C. V., Ballalai, C. S., Oliveira, J. C. A., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Domenech, J. Cebrián, Montalvo, A. Pinos, Chornet, T. Ciges, Martinez, P. Concha, Ribas, M. Piñol, Costa, R. Gimeno, Ortega, A. Castellanos, Forbes, C., Prescott, H., Lal, A., Khan, F. A., Dela Pena, E. G., Dizon, J. S., Perez, P. P. P., Wong, C. M. J., Garach, M. Muñoz, Romero, O. Moreno, Puerta, R. Ramirez, Diaz, F. Acosta, Bailon, A. M. Perez, Pinel, A. Carranza, Maldonado, L. Peñas, Kalaiselvan, M. S., kumar, R. L. Siva, Renuka, M. K., Kumar, A. S. Arun, De Rosa, S., Ferrari, F., Checcacci, S. Carboni, Rigobello, A., Joannidis, M., Politi, F., Pellizzari, A., Bonato, R., Fernandez-Carmona, A., Macias-Guarasa, I., Gutierrez-Rodriguez, R., Martinez-Lopez, P., Diaz-Castellanos, M. A., Fernandez-Carmona, A., Arias-Diaz, M., Aguilar-Alonso, E., Macias-Guarasa, I., Martinez-Lopez, P., Diaz-Castellanos, M. A., Nikandish, R. N., Artemenko, V., Budnyuk, A., Bassi, G. Li, Senussi, T., Idone, F., Xiol, E. Aguilera, Travierso, C., Chiurazzi, C., Motos, A., Amaro, R., Hua, Y., Fernández-Barat, L., Ranzani, O. T., Bobi, Q., Rigol, M., Torres, A., Youn, A., Hwang, J. Gyung, Garach, M. Muñoz, Romero, O. Moreno, Ossorio, M. E. Yuste, Diaz, F. Acosta, Bailon, A. M. Perez, Pinel, A. Carranza, Maldonado, L. Peñas, Teixeira, C., Figueira, H., Oliveira, R., Mota, A., Aragão, I., Kamp, O., Cruciger, O., Aach, M., Kaczmarek, C., Waydhas, C., Schildhauer, T. A., Hamsen, U., Camprubí-Rimblas, M., Chimenti, L., Guillamat-Prats, R., Lebouvier, T., Bringué, J., Tijero, J., Gómez, M. N., Blanch, L., Artigas, A., Tagliabue, G., Ji, M., Jagers, J. V. Suneby, Easton, P. A., Souza, R. B., Liberatore, A. M. A., Martins, A. M. C. R. P. F., Vieira, J. C. F., Kang, Y. R., Nakamae, M. N., Koh, I. H. J., Hong, J. Y., Shin, M. H., Park, M. S., Pomprapa, A., Pickerodt, P. A., Hofferberth, M. B. T., Russ, M., Braun, W., Walter, M., Francis, R., Lachmann, B., Leonhardt, S., Koh, I. H. J., Souza, R. B., Martins, A. M. C. R. P. F., Vieira, J. C. F., Liberatore, A. M. A., Landaverde-López, A., Canedo-Castillo, N. A., Esquivel-Chávez, A., Arvizu-Tachiquín, P. C., Sánchez-Hurtado, L. A., Baltazar-Torres, J. A., Cardoso, V., Krystopchuk, A., Castro, S., Melão, L., Firmino, S., Marreiros, A., Granja, C., Almaziad, S., Kubbara, A., Barnett, W., Nakity, R., Alamoudi, W., Altook, R., Tarazi, T., Fida, M., Safi, F., Assaly, R., Santini, A., Milesi, M., Maraffi, T., Pugni, P., Andreis, D. T., Cavenago, M., Gattinoni, L., Protti, A., Perchiazzi, G., Borges, J. B., Bayat, S., Porra, L., Broche, L., Pellegrini, M., Scaramuzzo, G., Hedenstierna, G., Larsson, A., Pellegrini, M., Hedenstierna, G., Roneus, A., Segelsjö, M., Vestito, M. C., Larsson, A., Perchiazzi, G., Gremo, E., Nyberg, A., Castegren, M., Pikwer, A., Yoshida, T., Engelberts, D., Otulakowski, G., Katira, B., Post, M., Ferguson, N. D., Brochard, L., Amato, M. B. P., Kavanagh, B. P., Koch, N., Huber, W., Hoellthaler, J., Mair, S., Phillip, V., Schmid, R. M., Beitz, A., Baladrón, V., Calvo, F. J. Redondo, Padilla, D., Villarejo, P., Villazala, R., Yuste, A. S., Bejarano, N., Steenstra, R. J., Banierink, H., Hof, J., van der Horst, I. C., Nijsten, M. W., Hoekstra, M., Roedl, K., Sterz, F., Horvatits, T., Horvatits, K., Drolz, A., Herkner, H., Fuhrmann, V., Kott, M., Zitta, K., Brandt, B., Schildhauer, C., Elke, G., Hummitzsch, L., Frerichs, I., Weiler, N., Albrecht, M., González, L. Rey, Alonso, D. Cabestrero, Ortiz, A. Blandino, Sánchez, R. de Pablo, Lucas, J. Higuera, Roedl, K., Sterz, F., Drolz, A., Horvatits, K., Horvatits, T., Herkner, H., Fuhrmann, V., Horvatits, T., Drolz, A., Roedl, K., Rutter, K., Ferlitsch, A., Fauler, G., Trauner, M., Fuhrmann, V., Horvatits, T., Pischke, S., Fischer, L., Thaiss, F., Koch, M., Bangert, K., Fuhrmann, V., Kluge, S., Lohse, A. W., Nashan, B., Sterneck, M., Faenza, S., Siniscalchi, A., Pierucci, E., Mancini, E., Ricci, D., Gemelli, C., Cuoghi, A., Magnani, S., Atti, M., Sotos, F., Cánovas, J., López, A., Burruezo, A., Torres, D., Herrera-Gutierrez, M. E., Barrueco-Francioni, J., Arias-Verdú, D., Lozano-Saez, R., Quesada-Garcia, G., Seller-Pérez, G., Figueiredo, A., Anzola, Y., Pereira, R., Bento, L., Arias-Verdú, D., Lai, M., Deiana, M., Barrueco-Francioni, J., Herrera-Gutierrez, M. E., Seller-Perez, G., Vardas, K., Ilia, S., Sertedaki, A., Charmadari, E., Stratakis, C. A., Briassouli, E., Goukos, D., Psarra, K., Botoula, E., Tsagarakis, S., Mageira, E., Routsi, C., Nanas, S., Briassoulis, G., Boscolo, A., Bertini, D., Campello, E., Lucchetta, V., Piasentini, E., Radu, C. M., Manesso, L., Simioni, P., Ori, C., Su, H., Lam, Y. M., Willis, K., Pullar, V., Hubner, R. P., Tsang, J. L., de Guadiana-Romualdo, L. García, Rebollo-Acebes, S., Esteban-Torrella, P., Jiménez-Sánchez, R., Jiménez-Santos, E., Ortín-Freire, A., Hernando-Holgado, A., Albaladejo-Otón, M. D., Coelho, L., Rabello, L., Salluh, J., Martin-Loeches, I., Rodriguez, A., Nseir, S., Póvoa, P., Varis, E., Pettilä, V., Poukkanen, M., Jacob, S., Karlsson, S., Perner, A., Takala, J., Wilkman, E., Lundberg, O. H. M., Bergenzaun, L., Rydén, J., Rosenqvist, M., Melander, O., Chew, M. S., Rodriguez-Ruiz, E., Vaquero, R. Hernández, Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Kishihara, Y., Yasuda, H., Rebollo, S., de Guadiana-Romualdo, L. García, Jimenez, R., Torrella, P. Esteban, Fernandez, A., Sanchez, S., Ortin, A., Bassi, G. Li, Prats, R. Guillamat, Artigas, A., Aguilera, E., Marti, D., Ranzani, O. T., Rigol, M., Fernandez, L., Ferrer, M., Martin-Loeches, I., Torres, A., Lanziotti, V. S., Póvoa, P., Pulcheri, L., Ribeiro, M. O., Barbosa, A. P., e Silva, J. R. Lapa, Soares, M., Salluh, J. I. F., Garcia, I. Palacios, Martin, A. Diaz, Marqués, M. Gil, Moreno, A. Puppo, Pizarraya, A. Gutierrez, Diaz, J. Pachón, Ibañez, M. Pachón, Smani, Y., Connell, M. Mc, Zhang, L. A., Parker, R. S., Banerjee, I., Clermont, G., Norberg, E., Oras, J., Cuisinier, A., Maufrais, C., Payen, J. F., Nottin, S., Walther, G., Bouzat, P., Arib, S., Bilotta, F., Badenes, R., Rubulotta, F., Mirek, S., Crippa, I. A., Monfort, B., Stazi, E., Roig, A. Lozano, Creteur, J., Taccone, F. S., Magnoni, S., Marando, M., Pifferi, S., Conte, V., Ortolano, F., Carbonara, M., Bertani, G., Scola, E., Cadioli, M., Triulzi, F., Colombo, A., Stocchetti, N., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Guimillo, M. Rodriguez, Piqueras, C. Sanchís, Guia, J. Romero, Simon, M. García, Arizmendi, A. Mesejo, Carratalá, A., El Maraghi, S., Yehia, A., Bakry, M., Shoman, A., Backes, F. N., Bianchin, M. M., Vieira, S. R. R., de Souza, A., Backes, A. N., Klein, C., Kalaiselvan, M. S., Renuka, M. K., Arunkumar, A. S., Lozano, A., Lheureux, O., Badenes, R., Vincent, J. L., Creteur, J., Taccone, F. S., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Geeraerts, T., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Rubulotta, F., Waldauf, P., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kovari, F., Kongpolprom, N., Gulia, V., Lourenço, E., Melão, L., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Marreiros, A., Granja, C., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Gupta, D., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., Abu-Habsa, M., Ahmad, A., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Honeybul, S., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Pelosi, P., Calzia, E., Radermacher, P., Nußbaum, B., Hartmann, C., Huber-Lang, M., Gröger, M., Radermacher, P., Nußbaum, B., Nußbaum, B., Antonucci, E., Calzia, E., Pelosi, P., Radermacher, P., Hartmann, C., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Carteron, L., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Sbraga, F., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Berbel-Franco, D., Dastis, M., Moreno-Gonzalez, G., Perez-Sanchez, J., Romera-Peregrina, I., Abellan-Lencina, R., Martinez-Pascual, A., Fuentes-Mila, V., Gonzalez-Romero, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Ampatzidou, F., Sileli, M., Kehagioglou, G., Madesis, A., Karaiskos, T., Moursia, C., Maleoglou, H., Leleki, K., Drossos, G., Uz, Z., Ince, Y., Papatella, R., Bulent, E., Guerci, P., Ince, C., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Fleischmann, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Gattinoni, L., Reinhart, K., Hartog, C. S., Pérez, A. González, Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Albaiceta, G. Muñiz, Tamura, T., Yatabe, T., Miyajima, I., Yamashita, K., Yokoyama, M., Ampatzidou, F., Kehagioglou, G., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Drossos, G., Hathorn, K. E., Purtle, S. W., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., Rubulotta, F., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Cánovas, J., Sotos, F., López, A., Lorente, M., Burruezo, A., Torres, D., Polok, K., Włudarczyk, A., Górka, J., Hałek, A., Musiał, J., Szczeklik, W., Jazia, A. Ben, Jaziri, F., Bargouth, M., Bennasr, M., Turki, S., Abdelghani, K. Ben, Abdallah, T. Ben, de Grooth, H. J., Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Wykes, K., Jack, J., Morgan, P., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Espinoza, E. D. Valenzuela, Welsh, S. P., Motta, M. F., Guerra, E., Zerpa, M. C. l., Zechner, F., Furche, M., Berdaguer, F., Birri, P. N. Rubatto, Risso-Vazquez, A., Dubin, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Sánchez-Hurtado, L. A., Arvizu-Tachiquín, P. C., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Baltazar-Torres, J. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Poulose, V., Morales, M. A. Lopez, Castro, S., Pires, T., Melão, L., Krystopchuk, A., Pereira, I., Granja, C., Taniguchi, L. U., Pires, E. M. C., Vieira, Jr, J. M., Azevedo, L. C. P., Nurses of the Central and General ICUs of Shiraz Namazi Hospital, Sedation an Delirium Group Hospital Universitari de Bellvitge, SPACeR group (Surrey Peri-operative, Anaesthesia and Critical Care Collaborative Research Group), for the PRoVENT investigators and the PROVE Network, SEMICYUC/GETGAG Working Group, TAVeM study group, POPC-CB investigators, DESIRE (DExmedetomidine for Sepsis in ICU Randomized Evaluation) Trial Investigators, GEMINI, Bioethics work group of SEMICYUC, The FINNAKI Study Group, Queen Square Neuroanaesthesia and Neurocritical Care Resreach Group, Renal Transplantation HUVR, GEMINI, EDISVAL Group, EDISVAL Group, PLUG Working group, TAVeM study Group, The FINNAKI Study Group, on behalf of Department of Professional Development, ESICM, Critical Care Research Group, SIRAKI group, and Grupo ESBAGA more...
Published: 2016
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3. Capsaicin patch 179 mg (CP) for the management of localized neuropathic pain (LNP) after breast cancer (BC) treatment

Author: Anchuelo, J., primary, Galdós, P., additional, Navarrete, P., additional, Alonso, L., additional, Rivero, A., additional, De Juan, A., additional, Cañon, V., additional, Albendea, J., additional, Pinto, F., additional, García, M., additional, Jimeno, J., additional, Paz, L., additional, Gutierrez, E., additional, Muñoz, A., additional, Díaz de Cerio, I., additional, Vazquez, C., additional, Borniquel, F., additional, Morán, I., additional, and Prada, P., additional more...
Published: 2022
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4. High-Flow Versus VenturiMask Oxygen Therapy to Prevent Reintubation in Hypoxemic Patients after Extubation: A Multicenter Randomized Clinical Trial

Author: Maggiore, S.M. Jaber, S. Grieco, D.L. Mancebo, J. Zakynthinos, S. Demoule, A. Ricard, J.-D. Navalesi, P. Vaschetto, R. Hraiech, S. Klouche, K. Frat, J.-P. Lemiale, V. Fanelli, V. Chanques, G. Natalini, D. Ischaki, E. Reuter, D. Morán, I. Combe, B.L. Longhini, F. De Gaetano, A. Ranieri, V.M. Brochard, L.J. Antonelli, M. RINO Trial Study Group and Maggiore, S.M. Jaber, S. Grieco, D.L. Mancebo, J. Zakynthinos, S. Demoule, A. Ricard, J.-D. Navalesi, P. Vaschetto, R. Hraiech, S. Klouche, K. Frat, J.-P. Lemiale, V. Fanelli, V. Chanques, G. Natalini, D. Ischaki, E. Reuter, D. Morán, I. Combe, B.L. Longhini, F. De Gaetano, A. Ranieri, V.M. Brochard, L.J. Antonelli, M. RINO Trial Study Group more...
Abstract: Rationale: When compared with VenturiMask after extubation, high-flow nasal oxygen provides physiological advantages. Objectives: To establish whether high-flow oxygen prevents endotracheal reintubation in hypoxemic patients after extubation, compared with VenturiMask. Methods: In this multicenter randomized trial, 494 patients exhibiting PaO2:FIO2 ratio < 300 mm Hg after extubation were randomly assigned to receive high-flow or VenturiMask oxygen, with the possibility to apply rescue noninvasive ventilation before reintubation. High-flow use in the VenturiMask group was not permitted. Measurements and Main Results: The primary outcome was the rate of reintubation within 72 hours according to predefined criteria, which were validated a posteriori by an independent adjudication committee. Main secondary outcomes included reintubation rate at 28 days and the need for rescue noninvasive ventilation according to predefined criteria. After intubation criteria validation (n = 492 patients), 32 patients (13%) in the high-flow group and 27 patients (11%) in the VenturiMask group required reintubation at 72 hours (unadjusted odds ratio, 1.26 [95% confidence interval (CI), 0.70–2.26]; P = 0.49). At 28 days, the rate of reintubation was 21% in the high-flow group and 23% in the VenturiMask group (adjusted hazard ratio, 0.89 [95% CI, 0.60–1.31]; P = 0.55). The need for rescue noninvasive ventilation was significantly lower in the high-flow group than in the VenturiMask group: at 72 hours, 8% versus 17% (adjusted hazard ratio, 0.39 [95% CI, 0.22–0.71]; P = 0.002) and at 28 days, 12% versus 21% (adjusted hazard ratio, 0.52 [95% CI, 0.32–0.83]; P = 0.007). Conclusions: Reintubation rate did not significantly differ between patients treated with VenturiMask or high-flow oxygen after extubation. High-flow oxygen yielded less frequent use of rescue noninvasive ventilation. Clinical trial registered with www.clinicaltrials.gov (NCT02107183). Copyright © 2022 by the American Tho more...
Published: 2022

5. Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study

Author: Universitat Rovira i Virgili, Wendel-Garcia PD; Mas A; González-Isern C; Ferrer R; Máñez R; Masclans JR; Sandoval E; Vera P; Trenado J; Fernández R; Sirvent JM; Martínez M; Ibarz M; Garro P; Lopera JL; Bodí M; Yébenes-Reyes JC; Triginer C; Vallverdú I; Baró A; Bodí F; Saludes P; Valencia M; Roche-Campo F; Huerta A; Cambra FJ; Barberà C; Echevarria J; Peñuelas Ó; Mancebo J; Ferrer R; Roca O; Nuvials X; Ruiz JC; Papiol E; Máñez R; Gumicio VD; Sandoval E; Muñoz G; Toapanta D; Castro P; Osorio J; Masclans JR; Muñoz-Bermúdez R; Parrilla F; Pérez-Teran P; Marin-Corral J; Mas A; Cancio B; Hernández-Marín S; Koborzan MR; Briones CA; Trenado J; Fernández R; Sirvent JM; Sebastian P; Saiz X; Martínez M; Ibarz M; Garro P; Pedrós C; Vendrell E; Lopera JL; Bodí M; Rodríguez A; Moreno G; Yébenes-Reves JC; Triginer C; Vallverdú I; Baró A; Morales M; Bodí F; Saludes P; Cervelló JR; Valencia M; Roche-Campo F; Franch-Llasat D; Huerta A; Santigosa P; Cambra FJ; Benito S; Barberà C; Echevarría J; Mancebo J; Vera P; Santos JA; Baldirà J; Betbesé AJ; Izura M; Morán I; Suárez JC; Zapata L; Rodríguez N; Torrens M; Cordón A; Gomila C; Flores M; Segarra A; Morales M; Mateo L; Martos M & González-Isern C, Universitat Rovira i Virgili, and Wendel-Garcia PD; Mas A; González-Isern C; Ferrer R; Máñez R; Masclans JR; Sandoval E; Vera P; Trenado J; Fernández R; Sirvent JM; Martínez M; Ibarz M; Garro P; Lopera JL; Bodí M; Yébenes-Reyes JC; Triginer C; Vallverdú I; Baró A; Bodí F; Saludes P; Valencia M; Roche-Campo F; Huerta A; Cambra FJ; Barberà C; Echevarria J; Peñuelas Ó; Mancebo J; Ferrer R; Roca O; Nuvials X; Ruiz JC; Papiol E; Máñez R; Gumicio VD; Sandoval E; Muñoz G; Toapanta D; Castro P; Osorio J; Masclans JR; Muñoz-Bermúdez R; Parrilla F; Pérez-Teran P; Marin-Corral J; Mas A; Cancio B; Hernández-Marín S; Koborzan MR; Briones CA; Trenado J; Fernández R; Sirvent JM; Sebastian P; Saiz X; Martínez M; Ibarz M; Garro P; Pedrós C; Vendrell E; Lopera JL; Bodí M; Rodríguez A; Moreno G; Yébenes-Reves JC; Triginer C; Vallverdú I; Baró A; Morales M; Bodí F; Saludes P; Cervelló JR; Valencia M; Roche-Campo F; Franch-Llasat D; Huerta A; Santigosa P; Cambra FJ; Benito S; Barberà C; Echevarría J; Mancebo J; Vera P; Santos JA; Baldirà J; Betbesé AJ; Izura M; Morán I; Suárez JC; Zapata L; Rodríguez N; Torrens M; Cordón A; Gomila C; Flores M; Segarra A; Morales M; Mateo L; Martos M & González-Isern C more...
Abstract: Background: Non-invasive oxygenation strategies have a prominent role in the treatment of acute hypoxemic respiratory failure during the coronavirus disease 2019 (COVID-19). While the efficacy of these therapies has been studied in hospitalized patients with COVID-19, the clinical outcomes associated with oxygen masks, high-flow oxygen therapy by nasal cannula and non-invasive mechanical ventilation in critically ill intensive care unit (ICU) patients remain unclear. Methods: In this retrospective study, we used the best of nine covariate balancing algorithms on all baseline covariates in critically ill COVID-19 patients supported with > 10 L of supplemental oxygen at one of the 26 participating ICUs in Catalonia, Spain, between March 14 and April 15, 2020. Results: Of the 1093 non-invasively oxygenated patients at ICU admission treated with one of the three stand-alone non-invasive oxygenation strategies, 897 (82%) required endotracheal intubation and 310 (28%) died during the ICU stay. High-flow oxygen therapy by nasal cannula (n = 439) and non-invasive mechanical ventilation (n = 101) were associated with a lower rate of endotracheal intubation (70% and 88%, respectively) than oxygen masks (n = 553 and 91% intubated), p < 0.001. Compared to oxygen masks, high-flow oxygen therapy by nasal cannula was associated with lower ICU mortality (hazard ratio 0.75 [95% CI 0.58–0.98), and the hazard ratio for ICU mortality was 1.21 [95% CI 0.80–1.83] for non-invasive mechanical ventilation. Conclusion: In critically ill COVID-19 ICU patients and, in the absence of conclusive data, high-flow oxygen therapy by nasal cannula may be the approach of choice as the primary non-invasive oxygenation support strategy. more...
Published: 2022

6. Ultra-Low Tidal Volumes And Extracorporeal Carbon Dioxide Removal (Hemolung® Ras) in Ards Patients. a Clinical Feasibility Study

Author: Parrilla, FJ, Bergesio, L, Aguirre-Bermeo, H, Suarez, JC, López, P, Morán, I, and Mancebo, J
Published: 2015
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7. Les suffixes dans la formation des noms d’origine en catalan

Author: Morán i Ocerinjauregui, Josep, primary
Published: 2002
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8. 175 (PB-088) Poster - Capsaicin patch 179 mg (CP) for the management of localized neuropathic pain (LNP) after breast cancer (BC) treatment

Author: Anchuelo, J., Galdós, P., Navarrete, P., Alonso, L., Rivero, A., De Juan, A., Cañon, V., Albendea, J., Pinto, F., García, M., Jimeno, J., Paz, L., Gutierrez, E., Muñoz, A., Díaz de Cerio, I., Vazquez, C., Borniquel, F., Morán, I., and Prada, P. more...
Published: 2022
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9. Intracerebral hemorrhage in ICU: is it worth treating?

Author: Sivakumar, S, Taccone, F, Desai, K, Lazaridis, C, Skarzynski, M, Sekhon, M, Henderson, W, Griesdale, D, Chapple, L, Deane, A, Williams, L, Strickland, R, Lange, K, Heyland, D, Chapman, M, Rowland, M, Garry, P, Westbrook, J, Corkill, R, Antoniades, C, Pattinson, K, Fatania, G, Strong, A, Myers, R, Jermaine, C, Robertson, C, Rusin, C, Hofmeijer, J, Sondag, L, Tjepkema Cloostermans, M, Beishuizen, A, Bosch, F, van Putten, M, Carteron, L, Patet, C, Solari, D, Oddo, M, Ali, M, Dias, C, Almeida, R, Vaz Ferreira, A, Silva, J, Monteiro, E, Cerejo, A, Rocha, A, Elsayed, A, Abougabal, A, Beshey, B, Alzahaby, K, Pozzebon, S, Ortiz, A, Cristallini, S, Lheureux, O, Brasseur, A, Vincent, J, Creteur, J, Hravnak, M, Yousef, K, Chang, Y, Crago, E, Friedlander, R, Abdelmonem, S, Tahon, S, Helmy, T, Meligy, H, Puig, F, Dunn Siegrist, I, Pugin, J, Gupta, S, Govil, D, Srinivasan, S, Patel, S, N, J, Gupta, A, Tomar, D, Shafi, M, Harne, R, Arora, D, Talwar, N, Mazumdar, S, Papakrivou, E, Makris, D, Manoulakas, E, Tsolaki, B, Karadodas, B, Zakynthinos, E, Garcia, I, Martin, A, Encinares, V, Ibañez, M, Montero, J, Labrador, G, Cangueiro, T, Poulose, V, Koh, J, Kam, J, Yeter, H, Kara, A, Aktepe, O, Topeli, A, Tsolakoglou, I, Intas, G, Stergiannis, P, Kolaros, A, Chalari, E, Athanasiadou, E, Martika, A, Fildisis, G, Faivre, V, Mengelle, C, Favier, B, Payen, D, Poppe, A, Winkler, M, Mudersbach, E, Schreiber, J, Wruck, M, Schwedhelm, E, Kluge, S, Zöllner, C, Tavladaki, T, Spanaki, A, Dimitriou, H, Kondili, E, Choulaki, C, Meleti, E, Kafetzopoulos, D, Georgopoulos, D, Briassoulis, G, la Torre, A, de la Torre Prados, M, Tsvetanova Spasova, T, Nuevo Ortega, P, Rueda Molina, C, Fernández Porcel, A, Camara Sola, E, Salido Díaz, L, García Alcántara, A, Meleti, D, Suberviola, B, Riera, J, Rellan, L, Sanchez, M, Robles, J, Lopez, E, Vicente, R, Miñambres, E, Santibañez, M, Le Guen, M, Moore, J, Mason, N, Windpassinger, M, Plattner, O, Mascha, E, Sessler, D, Research, O, Melia, U, Fontanet, J, van den Berg, J, Struys, M, Vereecke, H, Jensen, E, Rood, P, van de Schoor, F, van Tertholen, K, Pickkers, P, van den Boogaard, M, Beardow, Z, Redhead, H, Paramasivam, K, Numan, T, Kamper, A, Peelen, L, Zeman, P, Slooter, A, van Ewijk, C, Jacobs, G, Girbes, A, Myatra, S, Harish, M, Prabu, N, Siddiqui, S, Kulkarni, A, Divatia, J, Murbach, L, Leite, M, Osaku, E, Costa, C, Pelenz, M, Neitzke, N, Moraes, M, Jaskowiak, J, Silva, M, Zaponi, R, Abentroth, L, Ogasawara, S, Jorge, A, Duarte, P, Hernández Sánchez, N, Sánchez Hurtado, L, García Guillen, F, Ñamendys Silva, S, Maghsoudi, B, Emami, M, Khosravi, M, Zand, F, Tabatabaie, H, Masjedi, M, Sabetiyan, G, Mokri, A, Troubleyn, J, Diltoer, M, Jacobs, R, Nguyen, D, De Waele, E, De Regt, J, Honoré, P, Van Gorp, V, Spapen, H, Contreras, R, Toapanta, N, Moreno, G, Sabater, J, Torrado, H, Gonzalez, M, Marin, M, Farigola, E, Gonzalez, A, Fernandez, J, Vera, A, Gisbert, X, Juliá, C, Uya, J, Corral, L, Elias Jones, I, Gemmell, L, Mackay, A, Randall, D, Adwaney, A, Blunden, M, Prowle, J, Kirwan, C, Thomas, N, Owen, H, Darwin, L, Conway, D, Atkinson, D, Sharman, M, Barbanti, C, Amour, J, Gaudard, P, Rozec, B, Mauriat, P, M'Rini, M, Leger, P, Cambonie, G, Liet, J, Girard, C, Laroche, S, Damas, P, Assaf, Z, Loron, G, Lecourt, L, Pouard, P, Kim, S, Na, S, Kim, J, Oh, S, Jung, C, Yoo, S, Min, S, Chung, E, Lee, H, Lee, N, Lee, K, Suh, K, Ryu, H, Marshall, D, Goodson, R, Salciccioli, J, Shalhoub, J, Potter, E, Kirk Bayley, J, Karanjia, N, Forni, L, Creagh Brown, B, Bossy, M, Nyman, M, Tailor, A, D'Antini, D, Spadaro, S, Valentino, F, Sollitto, F, Cinnella, G, Mirabella, L, Calvo, F, Bejarano, N, Padilla, D, Baladron, V, Villajero, P, Villazala, R, Redondo, J, Yuste, A, Liu, J, Shen, F, Teboul, J, Anguel, N, Beurton, A, Bezaz, N, Richard, C, Monnet, X, Fossali, T, Colombo, R, Ottolina, D, Rossetti, M, Mazzucco, C, Marchi, A, Porta, A, Catena, E, Tollisen, K, Andersen, G, Heyerdahl, F, Jacobsen, D, de Waard, M, van IJzendoorn, M, Buter, H, Kingma, W, Navis, G, Boerma, E, Rulisek, J, Balik, M, Zacharov, S, Kim, H, Jeon, S, Namgung, H, Lee, E, Cho, Y, Lee, Y, Huang, A, Cioccari, L, Luethi, N, Mårtensson, J, Bellomo, R, Forsberg, M, Edman, G, Höjer, J, Forsberg, S, Freile, M, Hidalgo, F, Molina, J, Lecumberri, R, Rosselló, A, Travieso, P, Leon, G, Sanchez, J, Frias, L, Rosello, D, Verdejo, J, Serrano, J, Winterwerp, D, van Galen, T, Vazin, A, Karimzade, I, Zand, A, Ozen, E, Ekemen, S, Akcan, A, Sen, E, Yelken, B, Kureshi, N, Fenerty, L, Thibault Halman, G, Erdogan, M, Walling, S, Green, R, Clarke, D, Briassoulis, P, Kalimeris, K, Ntzouvani, A, Nomikos, T, Papaparaskeva, K, Politi, E, Kostopanagiotou, G, Crewdson, K, Rehn, M, Weaver, A, Brohi, K, Lockey, D, Wright, S, Thomas, K, Baker, C, Mansfield, L, Stafford, V, Wade, C, Watson, G, Bryant, A, Chadwick, T, Shen, J, Wilkinson, J, Furneval, J, Henderson, A, Hugill, K, Howard, P, Roy, A, Bonner, S, Baudouin, S, Ramírez, C, Escalada, S, Viera, M, Santana, M, Balcázar, L, Monroy, N, Campelo, F, Vázquez, C, Santana, P, Santana, S, Quintard, H, Bouzat, P, Wollersheim, T, Malleike, J, Haas, K, Carbon, N, Schneider, J, Birchmeier, C, Fielitz, J, Spuler, S, Weber Carstens, S, Enseñat, L, Pérez Madrigal, A, Saludes, P, Proença, L, Gruartmoner, G, Espinal, C, Mesquida, J, Huber, W, Eckmann, M, Elkmann, F, Gruber, A, Lahmer, T, Mayr, U, Herner, A, Schellnegger, R, Schmid, R, Ayoub, W, Samy, W, Esmat, A, Battah, A, Mukhtar, S, Mongkolpun, W, Cortés, D, Cordeiro, C, Funcke, S, Groesdonk, H, Saugel, B, Wagenpfeil, G, Wagenpfeil, S, Reuter, D, Fernandez, M, Fernandez, R, Magret, M, González Castro, A, Bouza, M, García, C, Balerdi, B, Mas, A, Arauzo, V, Añón, J, Ruiz, F, Ferreres, J, Tomás, R, Alabert, M, Tizón, A, Altaba, S, Llamas, N, Goligher, E, Fan, E, Herridge, M, Vorona, S, Sklar, M, Dres, M, Rittayamai, N, Lanys, A, Urrea, C, Tomlinson, G, Reid, W, Rubenfeld, G, Kavanagh, B, Brochard, L, Ferguson, N, Neto, A, de Abreu, M, Pelosi, P, Schultz, M, Guérin, C, Papazian, L, Reignier, J, Ayzac, L, Loundou, A, Forel, J, Rolland Debord, C, Bureau, C, Poitou, T, Clavel, M, Perbet, S, Terzi, N, Kouatchet, A, Similowski, T, Demoule, A, Hunfeld, N, Trogrlic, Z, Ladage, S, Osse, R, Koch, B, Rietdijk, W, Devlin, J, van der Jagt, M, Picetti, E, Ceccarelli, P, Mensi, F, Malchiodi, L, Risolo, S, Rossi, I, Antonini, M, Servadei, F, Caspani, M, Roquilly, A, Lasocki, S, Seguin, P, Geeraerts, T, Perrigault, P, Dahyot Fizelier, C, Paugam Burtz, C, Cook, F, Cinotti, R, Dit Latte, D, Mahe, P, Fortuit, C, Feuillet, F, Asehnoune, K, Marzorati, C, Spina, S, Scaravilli, V, Vargiolu, A, Riva, M, Barbadillo, S, de Molina, F, Álvarez Lerma, F, Rodríguez, A, Zakharkina, T, Martin Loeches, I, Matamoros, S, Povoa, P, Torres, A, Kastelijn, J, Hofstra, J, de Jong, M, Sterk, P, Artigas, A, Bos, L, Moreau, A, Salluh, J, Rodriguez, A, Nseir, S, de Jong, E, van Oers, J, Nijsten, M, de Lange, D, Bonvicini, D, Labate, D, Benacchio, L, Olivieri, A, Pizzirani, E, Lopez Delgado, J, Gonzalez Romero, M, Fuentes Mila, V, Berbel Franco, D, Romera Peregrina, I, Martinez Pascual, A, Perez Sanchez, J, Abellan Lencina, R, Ávila Espinoza, R, Moreno Gonzalez, G, Sbraga, F, Griffiths, S, Grocott, M, Doyle, J, Wilkerson, P, Soon, Y, Huddart, S, Dickinson, M, Riga, A, Zuleika, A, Miyamoto, K, Kawazoe, Y, Morimoto, T, Yamamoto, T, Fuke, A, Hashimoto, A, Koami, H, Beppu, S, Katayama, Y, Ito, M, Ohta, Y, Yamamura, H, Rygård, S, Holst, L, Wetterslev, J, Johansson, P, Perner, A, Soliman, I, van Dijk, D, van Delden, J, Cremer, O, Mcwilliams, D, Snelson, C, Neves, A, Loudet, C, Busico, M, Vazquez, D, Villalba, D, Veronesi, M, Lischinsky, A, López, F, Mori, L, Plotnikow, G, Díaz, A, Giannasi, S, Hernandez, R, Krzisnik, L, Cecotti, C, Viola, L, Lopez, R, Sottile, J, Benavent, G, Estenssoro, E, Chen, C, Lai, C, Cheng, K, Chou, W, Chan, K, Roeker, L, Horkan, C, Gibbons, F, Christopher, K, Weijs, P, Mogensen, K, Rawn, J, Robinson, M, Tang, Z, Qiu, C, Ouyang, B, Cai, C, Guan, X, Regueira, T, Cea, L, Carlos, S, Elisa, B, Puebla, C, Vargas, A, Poulsen, M, Thomsen, L, Kjærgaard, S, Rees, S, Karbing, D, Frank, S, Müller, M, Skrypnikov, V, Pickerodt, P, Falk, R, Mahlau, A, Lee, A, Inglis, R, Morgan, R, Barker, G, Kamata, K, Abe, T, Saitoh, D, Tokuda, Y, Butler, M, Hwa, H, Gil, L, Vaquero, R, Rodriguez Ruiz, E, Lago, A, Allut, J, Gestal, A, Thomas Rüddel, D, Schwarzkopf, D, Fleischmann, C, Reinhart, K, Suwanpasu, S, Sattayasomboon, Y, Filho, N, Oliveira, J, Ballalai, C, De Lucia, C, Araponga, G, Veiga, L, Silva, C, Garrido, M, Ramos, B, Ricaldi, E, Gomes, S, Wright, C, Docking, R, Doherty, P, Black, E, Stenhouse, P, Plummer, M, Finnis, M, Phillips, L, Kar, P, Bihari, S, Biradar, V, Moodie, S, Horowitz, M, Shaw, J, Yatabe, T, Inoue, S, Sakaguchi, M, Egi, M, Abdelhamid, Y, Hokka, M, Mizobuchi, S, Giersch, E, Summers, M, Hatzinikolas, S, Heller, S, Jones, K, Schweizer, R, Jacquet Lagreze, M, Portran, P, Junot, S, Allaouchiche, B, Fellahi, J, Guerci, P, Ergin, B, Kapucu, A, Ince, C, Crisman, M, Shinotsuka, C, Fagnoul, D, Orbegozo, D, Preiser, J, Thooft, A, Brimioulle, S, Iwasaka, H, Tahara, S, Nagamine, M, Ichigatani, A, Cabrera, A, Zepeda, E, Granillo, J, Sánchez, J, Montoya, A, Montenegro, A, Blanco, G, Robles, C, Drolz, A, Horvatits, T, Roedl, K, Rutter, K, Funk, G, Schneeweiss, B, Fuhrmann, V, Sabetian, G, Pooresmaeel, F, Ghaffaripour, S, Farbod, A, Tabei, H, Taheri, L, Anandanadesan, R, Metaxa, V, Teixeira, C, Pereira, S, Hernández Marrero, P, Carvalho, A, Beckmann, M, Hartog, C, Raadts, A, Robertsen, A, Førde, R, Skaga, N, Helseth, E, Honeybul, S, Ho, K, Lopez, P, Ortega, P, Sola, E, Spasova, T, Kopecky, O, Rusinova, K, Waldauf, P, Cepeplikova, Z, Domínguez, J, Almudevar, P, Carmona, S, Muñoz, J, Castañeda, D, Abellán, A, Villamizar, P, Ramos, J, Pérez, L, Lucendo, A, Ejarque, M, Estella, A, Camps, V, Martín, M, Masnou, N, Barbosa, S, Varela, A, Palma, I, Cristina, L, Nunes, E, Pereira, I, Campello, G, Granja, C, Pande, R, Pandey, M, Varghese, S, Chanu, M, Van Dam, M, Ter Braak, E, Gracia, M, Viciana, R, Recuerda, M, Fontaiña, L, Tharmalingam, B, Kovari, F, Rose, L, Mcginlay, M, Amin, R, Burns, K, Connolly, B, Hart, N, Jouvet, P, Katz, S, Leasa, D, Mawdsley, C, Mcauley, D, Blackwood, B, Denham, S, Worrall, R, Arshad, M, Isherwood, P, Khadjibaev, A, Sabirov, D, Rosstalnaya, A, Parpibaev, F, Sharipova, V, Guzman, C, Cha, Y, Lee, S, Tyagi, N, Rajput, R, Taneja, S, Singh, V, Sharma, S, Mittal, S, Rao, B, Ayachi, J, Fraj, N, Romdhani, S, Khedher, A, Meddeb, K, Sma, N, Azouzi, A, Bouneb, R, Chouchene, I, El Ghardallou, M, Boussarsar, M, Jennings, R, Walter, E, Ribeiro, J, Moniz, I, Marçal, R, Santos, A, Candeias, C, E. Silva, Z, Gomez, S, Nieto, O, Gonzalez, J, Cuellar, A, Mildh, H, Pettilä, V, Korhonen, A, Karlsson, S, Ala Kokko, T, Reinikainen, M, Vaara, S, Zaleska Kociecka, M, Grabowski, M, Dąbrowski, M, Wozniak, S, Piotrowska, K, Banaszewski, M, Imiela, J, Stepinska, J, Pérez, A, Ordoñez, P, Giribet, A, Cuervo, M, Cuervo, R, Esteban, M, Fraile, L, Mittelbrum, C, Albaiceta, G, Koeze, J, Keus, F, Dieperink, W, van der Horst, I, van Meurs, M, Zijlstra, J, Roberts, S, Caballero, C, Isgro, G, Hall, D, Beitland, S, Trøseid, A, Brusletto, B, Waldum Grevbo, B, Berg, J, Sunde, K, Huertas, D, Manzano, F, Quintana, M, Osuna, A, Santiago Ruiz, F, Rodríguez Mejías, C, Wangensteen, R, Jamaati, H, Hashemian, S, Abbasi, G, Khaloo, V, Tabei, S, Kafilzadeh, A, Bakhodaei, H, Diaz, J, Silva, R, Garcia, D, Luis, E, Gomez, M, Soriano, R, Gonzalez, P, Ibrahim, I, Rafik, M, Al Ansary, A, Algendi, M, Ali, A, Benten, D, Kluwe, J, Siedler, S, Adedugbe, I, Bird, G, Kennedy, R, Yugi, G, Haroon, B, Witter, T, Khaliq, W, Singer, M, Havaldar, A, Krishna, B, Sriram, S, Espinoza, E, Pozo, M, Edul, V, Furche, M, Motta, M, Vazquez, A, Birri, P, Dubin, A, Dogliotti, A, Ramos, A, Lovesio, C, Delile, E, Nevière, R, Thiébaut, P, Maupoint, J, Mulder, P, Coquerel, D, Renet, S, do Rego, J, Rieusset, J, Richard, V, Tamion, F, Andreis, D, Smit, B, Smulders, Y, van Straaten, H, Eringa, E, Man, A, Alegría, L, Soto, D, Luengo, C, Gomez, J, Jarufe, N, Bruhn, A, Castro, R, Kattan, E, Tapia, P, Rebolledo, R, Achurra, P, Ospina Tascón, G, Bakker, J, Hernández, G, Bertini, P, Guarracino, F, Baldassarri, R, Pinsky, M, Vera, M, Dreyse, J, Carpio, D, Henriquez, C, Gajardo, D, Bravo, S, Lee, M, Park, S, So, S, Kačar, M, Kačar, S, Uddin, I, Belhaj, A, Aydın, M, Avsec, D, Kapuağası, A, Kaymak, Ç, Kovach, L, Şencan, I, Meço, B, Özçelik, M, Ünal, N, Jenni Moser, B, Jeitziner, M, Galassi, M, Sales, F, de Moraes, K, Batista, C, Júnior, J, Marcari, T, Lobato, R, Castro, C, de Souza, L, Rodrigues, F, Correa, N, Pelegrini, A, Eid, R, Timenetsky, K, Cazati, D, Lobato, M, Diniz, P, Rocha, L, Cavalheiro, A, Lucinio, N, Santos, E, Norrenberg, M, Gleize, A, Simón, I, Valhonrat, I, Almudévar, P, Dávila, F, Rubio, J, Reina, Á, López, N, Pérez, M, Apolo, D, Villén, L, García, I, Izurieta, J, Guerrero, J, Calvert, S, Quint, M, Adeniji, K, Young, R, Shevill, D, Robertson, E, Garside, P, Isotti, P, De Vecchi, M, Perduca, A, Negro, A, Villa, G, Manara, D, Cabrini, L, Zangrillo, A, Frencken, J, van Baal, L, Donker, D, Horn, J, van der Poll, T, van Klei, W, Bonten, M, Menard, C, Kumar, A, Rimmer, E, Doucette, S, Turgeon, A, Houston, B, Houston, D, Zarychanski, R, Pinto, B, Carrara, M, Ferrario, M, Bendjelid, K, Nunes, J, Diaz, P, Silva, G, Escórcio, S, Chaves, S, Jardim, M, Fernandes, N, Câmara, M, Duarte, R, Pereira, C, Vieira, J, Nóbrega, J, de Oca Sandoval, M, Sánchez Rodríguez, A, Joya Galeana, J, Correa Morales, A, Camarena Alejo, G, Aguirre Sánchez, J, Franco Granillo, J, Soliman, M, Al Azab, A, El Hossainy, R, Nagy, H, Nirmalan, M, Crippa, I, Cavicchi, F, Chaari, A, Hakim, K, Hassanein, H, Etman, M, El Bahr, M, Bousselmi, K, Khalil, E, Kauts, V, Casey, W, Imahase, H, Sakamoto, Y, Yamada, K, Miike, T, Nagashima, F, Iwamura, T, Boscolo, A, Lucchetta, V, Piasentini, E, Bertini, D, Manesso, L, Spiezia, L, Simioni, P, Ori, C, Souza, R, Martins, A, Liberatore, A, Kang, Y, Nakamae, M, Koh, I, Hanslin, K, Wilske, F, Skorup, P, Sjölin, J, Lipcsey, M, Long, W, Zhen, C, Vakalos, A, Avramidis, V, Wu, S, Shyu, L, Li, C, Yu, C, Chen, H, Wang, C, Lin, K, Aray, Z, Gómez, C, Tejero, A, Monge, D, Losada, V, Tarancón, C, Cortés, S, Gutiérrez, A, Álvarez, T, Rouze, A, Jaffal, K, Six, S, Stolz, K, Cattoen, V, Arnal, J, Saoli, M, Novotni, D, Garnero, A, Becher, T, Buchholz, V, Schädler, D, Frerichs, I, Weiler, N, Eronia, N, Mauri, T, Gatti, S, Maffezzini, E, Bronco, A, Alban, L, Sasso, T, Marenghi, C, Grasselli, G, Pesenti, A, Bellani, G, Al Fares, A, Del Sorbo, L, Anwar, S, Facchin, F, Azad, S, Zamel, R, Cypel, M, Keshavjee, S, Durlinger, E, Spoelstra de Man, A, de Grooth, H, Straaten, H, Alfaro, M, Parrilla, F, Meli, A, Pellegrini, M, Rodriguez, N, Goyeneche, J, Morán, I, Aguirre, H, Mancebo, J, Heines, S, Strauch, U, Bergmans, D, Blankman, P, Shono, A, Hasan, D, Gommers, D, Chung, W, Jung, Y, Park, J, Sheen, S, Park, K, Worral, R, Larraza, S, Dey, N, Brohus, J, Winding, R, Volta, C, Ampatzidou, F, Vlachou, A, Kehagioglou, G, Karaiskos, T, Madesis, A, Mauromanolis, C, Michail, N, Drossos, G, Saraj, N, Rijkenberg, S, Feijen, H, Endeman, H, Donnelly, A, Morgan, E, Garrard, H, Buckley, H, Russell, L, Haase, N, Goh, C, Mouyis, K, Woodward, C, Halliday, J, Encina, G, Ros, J, Lagunes, L, Tabernero, J, Rello, J, Morente Constantin, E, Rivera Ginés, B, Colmenero Ruiz, M, Sanz, J, Simon, I, Valbuena, B, Pais, M, Ramalingam, S, Díaz, C, Fox, L, Santafe, M, Barba, P, García, M, Leal, S, Veganzones, J, Martínez, N, Moors, I, Mokart, D, Pène, F, Lambert, J, Mayaux, J, Vincent, F, Nyunga, M, Bruneel, F, Laisne, L, Rabbat, A, Lebert, C, Perez, P, Chaize, M, Renault, A, Meert, A, Hamidfar, R, Jourdain, M, Darmon, M, Schlemmer, B, Chevret, S, Lemiale, V, Azoulay, E, Benoit, D, Martins Branco, D, Sousa, M, Marum, S, Bouw, M, Galstyan, G, Makarova, P, Parovichnikova, E, Kuzmina, L, Troitskaya, V, Drize, N, Gemdzhian, E, Savchenko, V, Chao, H, Kılıc, E, Demiriz, B, Uygur, M, Sürücü, M, Cınar, K, Yıldırım, A, Kiss, K, Köves, B, Csernus, V, Molnár, Z, Ntantana, A, Matamis, D, Savvidou, S, Giannakou, M, Gouva, M, Nakos, G, Koulouras, V, Gaffney, S, Judge, C, Drew, T, Misran, H, Munshi, R, Mcgovern, L, Coyle, M, Dunne, L, Deasy, E, Lavin, P, Fahy, A, Darcy, D, Donnelly, M, Ismail, N, Hall, T, Wykes, K, Jack, J, Ngu, W, Morgan, P, Ruiz Ramos, J, Ramirez, P, Gordon, M, Villarreal, E, Frasquet, J, Poveda Andrés, J, Castellanos, A, Ijssennagger, C, Ten Hoorn, S, van Wijk, A, van den Broek, J, Tuinman, P, Elmenshawy, A, Hammond, B, Gibbon, G, Belcham, T, Burton, K, Taniguchi, L, Ramos, F, Momma, A, Martins Filho, A, Bartocci, J, Lopes, M, Sad, M, Rodrigues, C, Pires, E, Barreto, J, Duarte, S, Taba, S, Miglioranza, D, Gund, D, Lordani, C, Capuzzo, M, Corte, F, Terranova, S, Scaramuzzo, G, Fogagnolo, A, Bertacchini, S, Bellonzi, A, Ragazzi, R, Cruz, C, Nunes, A, Pereira, F, Aragão, I, Cardoso, A, Santos, C, Malheiro, M, Castro, H, Cardoso, T, Paratz, J, Kenardy, J, Comans, T, Coyer, F, Thomas, P, Boots, R, Pereira, N, Vilas Boas, A, Gomes, E, Torres, J, Carvalho, D, Molinos, E, Vales, C, Araújo, R, Karnatovskaia, L, Philbrick, K, Ognjen, G, Clark, M, Montero, R, Varas, J, Sánchez Elvira, L, Delgado, C, Díaz, P, Ruiz, B, Guerrero, A, Galache, J, Jiménez, R, Rebollo, S, Alejandro, O, Fernández, A, Moreno, S, Herrera, L, Ojados, A, Galindo, M, Murcia, J, Contreras, M, Sánchez Argente, S, Bonilla, Y, Rodríguez, M, Allegue, J, Cakin, Ö, Parlak, H, Kirca, H, Mutlu, F, Aydınlı, B, Cengiz, M, Ramazanoglu, A, Jung, E, Domenech, J, Montalvo, A, Chornet, T, Martinez, P, Ribas, M, Costa, R, Ortega, A, Forbes, C, Prescott, H, Lal, A, Khan, F, Dela Pena, E, Dizon, J, Wong, C, Garach, M, Romero, O, Puerta, R, Diaz, F, Bailon, A, Pinel, A, Maldonado, L, Kalaiselvan, M, Kumar, R, Renuka, M, De Rosa, S, Ferrari, F, Checcacci, S, Rigobello, A, Joannidis, M, Politi, F, Pellizzari, A, Bonato, R, Fernandez Carmona, A, Macias Guarasa, I, Gutierrez Rodriguez, R, Martinez Lopez, P, Diaz Castellanos, M, Arias Diaz, M, Aguilar Alonso, E, Nikandish, R, Artemenko, V, Budnyuk, A, Bassi, G, Senussi, T, Idone, F, Xiol, E, Travierso, C, Chiurazzi, C, Motos, A, Amaro, R, Hua, Y, Fernández Barat, L, Ranzani, O, Bobi, Q, Rigol, M, Youn, A, Hwang, J, Ossorio, M, Figueira, H, Oliveira, R, Mota, A, Kamp, O, Cruciger, O, Aach, M, Kaczmarek, C, Waydhas, C, Schildhauer, T, Hamsen, U, Camprubí Rimblas, M, Chimenti, L, Guillamat Prats, R, Lebouvier, T, Bringué, J, Tijero, J, Gómez, M, Blanch, L, Tagliabue, G, Ji, M, Jagers, J, Easton, P, Hong, J, Shin, M, Park, M, Pomprapa, A, Hofferberth, M, Russ, M, Braun, W, Walter, M, Francis, R, Lachmann, B, Leonhardt, S, Landaverde López, A, Canedo Castillo, N, Esquivel Chávez, A, Arvizu Tachiquín, P, Baltazar Torres, J, Cardoso, V, Krystopchuk, A, Castro, S, Melão, L, Firmino, S, Marreiros, A, Almaziad, S, Kubbara, A, Barnett, W, Nakity, R, Alamoudi, W, Altook, R, Tarazi, T, Fida, M, Safi, F, Assaly, R, Santini, A, Milesi, M, Maraffi, T, Pugni, P, Cavenago, M, Gattinoni, L, Protti, A, Perchiazzi, G, Borges, J, Bayat, S, Porra, L, Broche, L, Hedenstierna, G, Larsson, A, Roneus, A, Segelsjö, M, Vestito, M, Gremo, E, Nyberg, A, Castegren, M, Pikwer, A, Yoshida, T, Engelberts, D, Otulakowski, G, Katira, B, Post, M, Amato, M, Koch, N, Hoellthaler, J, Mair, S, Phillip, V, Beitz, A, Baladrón, V, Villarejo, P, Steenstra, R, Banierink, H, Hof, J, Hoekstra, M, Sterz, F, Horvatits, K, Herkner, H, Kott, M, Zitta, K, Brandt, B, Schildhauer, C, Elke, G, Hummitzsch, L, Albrecht, M, González, L, Alonso, D, Sánchez, R, Lucas, J, Ferlitsch, A, Fauler, G, Trauner, M, Pischke, S, Fischer, L, Thaiss, F, Koch, M, Bangert, K, Lohse, A, Nashan, B, Sterneck, M, Faenza, S, Siniscalchi, A, Pierucci, E, Mancini, E, Ricci, D, Gemelli, C, Cuoghi, A, Magnani, S, Atti, M, Sotos, F, Cánovas, J, López, A, Burruezo, A, Torres, D, Herrera Gutierrez, M, Barrueco Francioni, J, Arias Verdú, D, Lozano Saez, R, Quesada Garcia, G, Seller Pérez, G, Figueiredo, A, Anzola, Y, Pereira, R, Bento, L, Lai, M, Deiana, M, Seller Perez, G, Vardas, K, Ilia, S, Sertedaki, A, Charmadari, E, Stratakis, C, Briassouli, E, Goukos, D, Psarra, K, Botoula, E, Tsagarakis, S, Mageira, E, Routsi, C, Nanas, S, Campello, E, Radu, C, Su, H, Lam, Y, Willis, K, Pullar, V, Hubner, R, Tsang, J, de Guadiana Romualdo, L, Rebollo Acebes, S, Esteban Torrella, P, Jiménez Sánchez, R, Jiménez Santos, E, Ortín Freire, A, Hernando Holgado, A, Albaladejo Otón, M, Coelho, L, Rabello, L, Póvoa, P, Varis, E, Poukkanen, M, Jacob, S, Takala, J, Wilkman, E, Lundberg, O, Bergenzaun, L, Rydén, J, Rosenqvist, M, Melander, O, Chew, M, Kishihara, Y, Yasuda, H, Jimenez, R, Torrella, P, Fernandez, A, Sanchez, S, Ortin, A, Prats, R, Aguilera, E, Marti, D, Fernandez, L, Ferrer, M, Lanziotti, V, Pulcheri, L, Ribeiro, M, Barbosa, A, E. Silva, J, Soares, M, Marqués, M, Moreno, A, Pizarraya, A, Smani, Y, Connell, M, Zhang, L, Parker, R, Banerjee, I, Clermont, G, Norberg, E, Oras, J, Cuisinier, A, Maufrais, C, Payen, J, Nottin, S, Walther, G, Arib, S, Bilotta, F, Badenes, R, Rubulotta, F, Mirek, S, Monfort, B, Stazi, E, Roig, A, Magnoni, S, Marando, M, Pifferi, S, Conte, V, Ortolano, F, Carbonara, M, Bertani, G, Scola, E, Cadioli, M, Triulzi, F, Colombo, A, Stocchetti, N, Rotzel, H, Lázaro, A, Prada, D, Guimillo, M, Piqueras, C, Guia, J, Simon, M, Arizmendi, A, Carratalá, A, El Maraghi, S, Yehia, A, Bakry, M, Shoman, A, Backes, F, Bianchin, M, Vieira, S, de Souza, A, Backes, A, Klein, C, Arunkumar, A, Lozano, A, Gallaher, C, Cattlin, S, Gordon, S, Picard, J, Fontana, V, Bond, O, Nobile, L, Mrozek, S, Delamarre, L, Capilla, F, Al Saati, T, Fourcade, O, Dominguez Berrot, A, Gonzalez Vaquero, M, Vallejo Pascual, M, Gupta, D, Ivory, B, Chopra, M, Mccarthy, J, Felderhof, C, Macneil, C, Maggiorini, M, Duska, F, Fumis, R, Junior, J, Amarante, G, Skorko, A, Sanders, S, Aron, J, Kroll, R, Redfearn, C, Krishnan, P, Khalil, J, Kongpolprom, N, Gulia, V, Lourenço, E, Duro, C, Baptista, G, Alves, A, Arminda, B, Rodrigues, M, Hayward, J, Baldwin, F, Gray, R, Katinakis, P, Stijf, M, Ten Kleij, M, Jansen Frederiks, M, Broek, R, de Bruijne, M, Spronk, P, Sinha, K, Luney, M, Palmer, K, Keating, L, Abu Habsa, M, Bahl, R, Baskaralingam, N, Ahmad, A, Kanapeckaite, L, Bhatti, P, Glace, S, Jeyabraba, S, Lewis, H, Kostopoulos, A, Raja, M, West, A, Ely, A, Turkoglu, L, Zolfaghari, P, Baptista, J, Marques, M, Martins, P, Pimentel, J, Su, Y, Villacres, S, Stone, M, Parsikia, A, Medar, S, O'Dea, K, Porter, J, Tirlapur, N, Jonathan, J, Singh, S, Takata, M, Mcwhirter, E, Lyon, R, Hariz, M, Azmi, E, Alkhan, J, Movsisyan, V, Petrikov, S, Marutyan, Z, Aliev, I, Evdokimov, A, Antonucci, E, Merz, T, Hartmann, C, Calzia, E, Radermacher, P, Nußbaum, B, Huber Lang, M, Gröger, M, Svoren Jabalera, E, Davenport, E, Humburg, P, Knight, J, Hinds, C, Jun, I, Kim, W, Besch, G, Perrotti, A, Puyraveau, M, Baltres, M, Samain, E, Chocron, S, Pili Floury, S, Plata Menchaca, E, Sabater Riera, J, Estruch, M, Boza, E, Toscana Fernández, J, Bruguera Pellicer, E, Ordoñez Llanos, J, Pérez Fernández, X, Cavaleiro, P, Tralhão, A, Arrigo, M, Lopes, J, Lebrun, M, Cholley, B, Perezvela, J, Marinmateos, H, Rivera, J, Llorente, M, De Marcos, B, Fernandez, F, Laborda, C, Zamora, D, Delgado, J, Imperiali, C, Dastis, M, Górka, J, Górka, K, Iwaniec, T, Frołow, M, Polok, K, Fronczek, J, Kózka, M, Musiał, J, Szczeklik, W, Sileli, M, Moursia, C, Maleoglou, H, Leleki, K, Uz, Z, Ince, Y, Papatella, R, Bulent, E, De Mol, B, Vicka, V, Gineityte, D, Ringaitiene, D, Norkiene, I, Sipylaite, J, Möller, C, Thomas Rueddel, D, Vlasakov, V, Rochwerg, B, Theurer, P, Al Sibai, J, Camblor, P, Fernandez, P, Gala, J, Guisasola, J, Tamura, T, Miyajima, I, Yamashita, K, Yokoyama, M, Dalampini, E, Nastou, M, Baddour, A, Ignatiadis, A, Asteri, T, Hathorn, K, Purtle, S, Viana, M, Tonietto, T, Gross, L, Costa, V, Tavares, A, Lisboa, B, Moraes, R, Viana, L, Azevedo, M, Ceniccola, G, Pequeno, R, Holanda, T, Mendonça, V, Araújo, W, Carvalho, L, Segaran, E, Vickers, L, Brinchmann, K, Wignall, I, De Brito Ashurst, I, Del Olmo, R, Vaquerizo, C, Carreño, R, Gálvez, V, Kaminsky, G, Nieto, B, Fuentes, M, De la Torre, M, Torres, E, Alonso, A, Velayos, C, Saldaña, T, Escribá, A, Grip, J, Kölegård, R, Sundblad, P, Rooyackers, O, Naser, B, Jaziri, F, Jazia, A, Barghouth, M, Hentati, O, Skouri, W, El Euch, M, Mahfoudhi, M, Turki, S, Abdelghni, K, Abdallah, B, Maha, B, Lorente, M, Włudarczyk, A, Hałek, A, Bargouth, M, Bennasr, M, Abdelghani, K, Abdallah, T, Geenen, I, Parienti, J, Shum, H, King, H, Yan, W, Londoño, J, Cardenas, C, Pedrosa, M, Gubianas, C, Bertolin, C, Batllori, N, Sirvent, J, Mukhopadhyay, A, Chan, H, Kowitlawakul, Y, Remani, D, Leong, C, Henry, C, Puthucheary, Z, Mendsaikhan, N, Begzjav, T, Lundeg, G, Dünser, M, Welsh, S, Guerra, E, Zerpa, M, Zechner, F, Berdaguer, F, Risso Vazquez, A, Masevicius, F, Greaney, D, Magee, A, Fitzpatrick, G, Lugo Cob, R, Tejeda Huezo, B, Cano Oviedo, A, Aydogan, M, Togal, T, Taha, A, Chai, H, Kam, C, Razali, S, Sivasamy, V, Kuan, L, Morales, M, Pires, T, Azevedo, L., GIUSSANI, CARLO GIORGIO, SGANZERLA, ERIK PIETRO, CITERIO, GIUSEPPE, Sivakumar, S, Taccone, F, Desai, K, Lazaridis, C, Skarzynski, M, Sekhon, M, Henderson, W, Griesdale, D, Chapple, L, Deane, A, Williams, L, Strickland, R, Lange, K, Heyland, D, Chapman, M, Rowland, M, Garry, P, Westbrook, J, Corkill, R, Antoniades, C, Pattinson, K, Fatania, G, Strong, A, Myers, R, Jermaine, C, Robertson, C, Rusin, C, Hofmeijer, J, Sondag, L, Tjepkema Cloostermans, M, Beishuizen, A, Bosch, F, van Putten, M, Carteron, L, Patet, C, Solari, D, Oddo, M, Ali, M, Dias, C, Almeida, R, Vaz Ferreira, A, Silva, J, Monteiro, E, Cerejo, A, Rocha, A, Elsayed, A, Abougabal, A, Beshey, B, Alzahaby, K, Pozzebon, S, Ortiz, A, Cristallini, S, Lheureux, O, Brasseur, A, Vincent, J, Creteur, J, Hravnak, M, Yousef, K, Chang, Y, Crago, E, Friedlander, R, Abdelmonem, S, Tahon, S, Helmy, T, Meligy, H, Puig, F, Dunn Siegrist, I, Pugin, J, Gupta, S, Govil, D, Srinivasan, S, Patel, S, N, J, Gupta, A, Tomar, D, Shafi, M, Harne, R, Arora, D, Talwar, N, Mazumdar, S, Papakrivou, E, Makris, D, Manoulakas, E, Tsolaki, B, Karadodas, B, Zakynthinos, E, Garcia, I, Martin, A, Encinares, V, Ibañez, M, Montero, J, Labrador, G, Cangueiro, T, Poulose, V, Koh, J, Kam, J, Yeter, H, Kara, A, Aktepe, O, Topeli, A, Tsolakoglou, I, Intas, G, Stergiannis, P, Kolaros, A, Chalari, E, Athanasiadou, E, Martika, A, Fildisis, G, Faivre, V, Mengelle, C, Favier, B, Payen, D, Poppe, A, Winkler, M, Mudersbach, E, Schreiber, J, Wruck, M, Schwedhelm, E, Kluge, S, Zöllner, C, Tavladaki, T, Spanaki, A, Dimitriou, H, Kondili, E, Choulaki, C, Meleti, E, Kafetzopoulos, D, Georgopoulos, D, Briassoulis, G, la Torre, A, de la Torre Prados, M, Tsvetanova Spasova, T, Nuevo Ortega, P, Rueda Molina, C, Fernández Porcel, A, Camara Sola, E, Salido Díaz, L, García Alcántara, A, Meleti, D, Suberviola, B, Riera, J, Rellan, L, Sanchez, M, Robles, J, Lopez, E, Vicente, R, Miñambres, E, Santibañez, M, Le Guen, M, Moore, J, Mason, N, Windpassinger, M, Plattner, O, Mascha, E, Sessler, D, Research, O, Melia, U, Fontanet, J, van den Berg, J, Struys, M, Vereecke, H, Jensen, E, Rood, P, van de Schoor, F, van Tertholen, K, Pickkers, P, van den Boogaard, M, Beardow, Z, Redhead, H, Paramasivam, K, Numan, T, Kamper, A, Peelen, L, Zeman, P, Slooter, A, van Ewijk, C, Jacobs, G, Girbes, A, Myatra, S, Harish, M, Prabu, N, Siddiqui, S, Kulkarni, A, Divatia, J, Murbach, L, Leite, M, Osaku, E, Costa, C, Pelenz, M, Neitzke, N, Moraes, M, Jaskowiak, J, Silva, M, Zaponi, R, Abentroth, L, Ogasawara, S, Jorge, A, Duarte, P, Hernández Sánchez, N, Sánchez Hurtado, L, García Guillen, F, Ñamendys Silva, S, Maghsoudi, B, Emami, M, Khosravi, M, Zand, F, Tabatabaie, H, Masjedi, M, Sabetiyan, G, Mokri, A, Troubleyn, J, Diltoer, M, Jacobs, R, Nguyen, D, De Waele, E, De Regt, J, Honoré, P, Van Gorp, V, Spapen, H, Contreras, R, Toapanta, N, Moreno, G, Sabater, J, Torrado, H, Gonzalez, M, Marin, M, Farigola, E, Gonzalez, A, Fernandez, J, Vera, A, Gisbert, X, Juliá, C, Uya, J, Corral, L, Elias Jones, I, Gemmell, L, Mackay, A, Randall, D, Adwaney, A, Blunden, M, Prowle, J, Kirwan, C, Thomas, N, Owen, H, Darwin, L, Conway, D, Atkinson, D, Sharman, M, Barbanti, C, Amour, J, Gaudard, P, Rozec, B, Mauriat, P, M'Rini, M, Leger, P, Cambonie, G, Liet, J, Girard, C, Laroche, S, Damas, P, Assaf, Z, Loron, G, Lecourt, L, Pouard, P, Kim, S, Na, S, Kim, J, Oh, S, Jung, C, Yoo, S, Min, S, Chung, E, Lee, H, Lee, N, Lee, K, Suh, K, Ryu, H, Marshall, D, Goodson, R, Salciccioli, J, Shalhoub, J, Potter, E, Kirk Bayley, J, Karanjia, N, Forni, L, Creagh Brown, B, Bossy, M, Nyman, M, Tailor, A, D'Antini, D, Spadaro, S, Valentino, F, Sollitto, F, Cinnella, G, Mirabella, L, Calvo, F, Bejarano, N, Padilla, D, Baladron, V, Villajero, P, Villazala, R, Redondo, J, Yuste, A, Liu, J, Shen, F, Teboul, J, Anguel, N, Beurton, A, Bezaz, N, Richard, C, Monnet, X, Fossali, T, Colombo, R, Ottolina, D, Rossetti, M, Mazzucco, C, Marchi, A, Porta, A, Catena, E, Tollisen, K, Andersen, G, Heyerdahl, F, Jacobsen, D, de Waard, M, van IJzendoorn, M, Buter, H, Kingma, W, Navis, G, Boerma, E, Rulisek, J, Balik, M, Zacharov, S, Kim, H, Jeon, S, Namgung, H, Lee, E, Cho, Y, Lee, Y, Huang, A, Cioccari, L, Luethi, N, Mårtensson, J, Bellomo, R, Forsberg, M, Edman, G, Höjer, J, Forsberg, S, Freile, M, Hidalgo, F, Molina, J, Lecumberri, R, Rosselló, A, Travieso, P, Leon, G, Sanchez, J, Frias, L, Rosello, D, Verdejo, J, Serrano, J, Winterwerp, D, van Galen, T, Vazin, A, Karimzade, I, Zand, A, Ozen, E, Ekemen, S, Akcan, A, Sen, E, Yelken, B, Kureshi, N, Fenerty, L, Thibault Halman, G, Erdogan, M, Walling, S, Green, R, Clarke, D, Briassoulis, P, Kalimeris, K, Ntzouvani, A, Nomikos, T, Papaparaskeva, K, Politi, E, Kostopanagiotou, G, Crewdson, K, Rehn, M, Weaver, A, Brohi, K, Lockey, D, Wright, S, Thomas, K, Baker, C, Mansfield, L, Stafford, V, Wade, C, Watson, G, Bryant, A, Chadwick, T, Shen, J, Wilkinson, J, Furneval, J, Henderson, A, Hugill, K, Howard, P, Roy, A, Bonner, S, Baudouin, S, Ramírez, C, Escalada, S, Viera, M, Santana, M, Balcázar, L, Monroy, N, Campelo, F, Vázquez, C, Santana, P, Santana, S, Quintard, H, Bouzat, P, Wollersheim, T, Malleike, J, Haas, K, Carbon, N, Schneider, J, Birchmeier, C, Fielitz, J, Spuler, S, Weber Carstens, S, Enseñat, L, Pérez Madrigal, A, Saludes, P, Proença, L, Gruartmoner, G, Espinal, C, Mesquida, J, Huber, W, Eckmann, M, Elkmann, F, Gruber, A, Lahmer, T, Mayr, U, Herner, A, Schellnegger, R, Schmid, R, Ayoub, W, Samy, W, Esmat, A, Battah, A, Mukhtar, S, Mongkolpun, W, Cortés, D, Cordeiro, C, Funcke, S, Groesdonk, H, Saugel, B, Wagenpfeil, G, Wagenpfeil, S, Reuter, D, Fernandez, M, Fernandez, R, Magret, M, González Castro, A, Bouza, M, García, C, Balerdi, B, Mas, A, Arauzo, V, Añón, J, Ruiz, F, Ferreres, J, Tomás, R, Alabert, M, Tizón, A, Altaba, S, Llamas, N, Goligher, E, Fan, E, Herridge, M, Vorona, S, Sklar, M, Dres, M, Rittayamai, N, Lanys, A, Urrea, C, Tomlinson, G, Reid, W, Rubenfeld, G, Kavanagh, B, Brochard, L, Ferguson, N, Neto, A, de Abreu, M, Pelosi, P, Schultz, M, Guérin, C, Papazian, L, Reignier, J, Ayzac, L, Loundou, A, Forel, J, Rolland Debord, C, Bureau, C, Poitou, T, Clavel, M, Perbet, S, Terzi, N, Kouatchet, A, Similowski, T, Demoule, A, Hunfeld, N, Trogrlic, Z, Ladage, S, Osse, R, Koch, B, Rietdijk, W, Devlin, J, van der Jagt, M, Picetti, E, Ceccarelli, P, Mensi, F, Malchiodi, L, Risolo, S, Rossi, I, Antonini, M, Servadei, F, Caspani, M, Roquilly, A, Lasocki, S, Seguin, P, Geeraerts, T, Perrigault, P, Dahyot Fizelier, C, Paugam Burtz, C, Cook, F, Cinotti, R, Dit Latte, D, Mahe, P, Fortuit, C, Feuillet, F, Asehnoune, K, Marzorati, C, Spina, S, Scaravilli, V, Vargiolu, A, Riva, M, Giussani, C, Sganzerla, E, Citerio, G, Barbadillo, S, de Molina, F, Álvarez Lerma, F, Rodríguez, A, Zakharkina, T, Martin Loeches, I, Matamoros, S, Povoa, P, Torres, A, Kastelijn, J, Hofstra, J, de Jong, M, Sterk, P, Artigas, A, Bos, L, Moreau, A, Salluh, J, Rodriguez, A, Nseir, S, de Jong, E, van Oers, J, Nijsten, M, de Lange, D, Bonvicini, D, Labate, D, Benacchio, L, Olivieri, A, Pizzirani, E, Lopez Delgado, J, Gonzalez Romero, M, Fuentes Mila, V, Berbel Franco, D, Romera Peregrina, I, Martinez Pascual, A, Perez Sanchez, J, Abellan Lencina, R, Ávila Espinoza, R, Moreno Gonzalez, G, Sbraga, F, Griffiths, S, Grocott, M, Doyle, J, Wilkerson, P, Soon, Y, Huddart, S, Dickinson, M, Riga, A, Zuleika, A, Miyamoto, K, Kawazoe, Y, Morimoto, T, Yamamoto, T, Fuke, A, Hashimoto, A, Koami, H, Beppu, S, Katayama, Y, Ito, M, Ohta, Y, Yamamura, H, Rygård, S, Holst, L, Wetterslev, J, Johansson, P, Perner, A, Soliman, I, van Dijk, D, van Delden, J, Cremer, O, Mcwilliams, D, Snelson, C, Neves, A, Loudet, C, Busico, M, Vazquez, D, Villalba, D, Veronesi, M, Lischinsky, A, López, F, Mori, L, Plotnikow, G, Díaz, A, Giannasi, S, Hernandez, R, Krzisnik, L, Cecotti, C, Viola, L, Lopez, R, Sottile, J, Benavent, G, Estenssoro, E, Chen, C, Lai, C, Cheng, K, Chou, W, Chan, K, Roeker, L, Horkan, C, Gibbons, F, Christopher, K, Weijs, P, Mogensen, K, Rawn, J, Robinson, M, Tang, Z, Qiu, C, Ouyang, B, Cai, C, Guan, X, Regueira, T, Cea, L, Carlos, S, Elisa, B, Puebla, C, Vargas, A, Poulsen, M, Thomsen, L, Kjærgaard, S, Rees, S, Karbing, D, Frank, S, Müller, M, Skrypnikov, V, Pickerodt, P, Falk, R, Mahlau, A, Lee, A, Inglis, R, Morgan, R, Barker, G, Kamata, K, Abe, T, Saitoh, D, Tokuda, Y, Butler, M, Hwa, H, Gil, L, Vaquero, R, Rodriguez Ruiz, E, Lago, A, Allut, J, Gestal, A, Thomas Rüddel, D, Schwarzkopf, D, Fleischmann, C, Reinhart, K, Suwanpasu, S, Sattayasomboon, Y, Filho, N, Oliveira, J, Ballalai, C, De Lucia, C, Araponga, G, Veiga, L, Silva, C, Garrido, M, Ramos, B, Ricaldi, E, Gomes, S, Wright, C, Docking, R, Doherty, P, Black, E, Stenhouse, P, Plummer, M, Finnis, M, Phillips, L, Kar, P, Bihari, S, Biradar, V, Moodie, S, Horowitz, M, Shaw, J, Yatabe, T, Inoue, S, Sakaguchi, M, Egi, M, Abdelhamid, Y, Hokka, M, Mizobuchi, S, Giersch, E, Summers, M, Hatzinikolas, S, Heller, S, Jones, K, Schweizer, R, Jacquet Lagreze, M, Portran, P, Junot, S, Allaouchiche, B, Fellahi, J, Guerci, P, Ergin, B, Kapucu, A, Ince, C, Crisman, M, Shinotsuka, C, Fagnoul, D, Orbegozo, D, Preiser, J, Thooft, A, Brimioulle, S, Iwasaka, H, Tahara, S, Nagamine, M, Ichigatani, A, Cabrera, A, Zepeda, E, Granillo, J, Sánchez, J, Montoya, A, Montenegro, A, Blanco, G, Robles, C, Drolz, A, Horvatits, T, Roedl, K, Rutter, K, Funk, G, Schneeweiss, B, Fuhrmann, V, Sabetian, G, Pooresmaeel, F, Ghaffaripour, S, Farbod, A, Tabei, H, Taheri, L, Anandanadesan, R, Metaxa, V, Teixeira, C, Pereira, S, Hernández Marrero, P, Carvalho, A, Beckmann, M, Hartog, C, Raadts, A, Robertsen, A, Førde, R, Skaga, N, Helseth, E, Honeybul, S, Ho, K, Lopez, P, Ortega, P, Sola, E, Spasova, T, Kopecky, O, Rusinova, K, Waldauf, P, Cepeplikova, Z, Domínguez, J, Almudevar, P, Carmona, S, Muñoz, J, Castañeda, D, Abellán, A, Villamizar, P, Ramos, J, Pérez, L, Lucendo, A, Ejarque, M, Estella, A, Camps, V, Martín, M, Masnou, N, Barbosa, S, Varela, A, Palma, I, Cristina, L, Nunes, E, Pereira, I, Campello, G, Granja, C, Pande, R, Pandey, M, Varghese, S, Chanu, M, Van Dam, M, Ter Braak, E, Gracia, M, Viciana, R, Recuerda, M, Fontaiña, L, Tharmalingam, B, Kovari, F, Rose, L, Mcginlay, M, Amin, R, Burns, K, Connolly, B, Hart, N, Jouvet, P, Katz, S, Leasa, D, Mawdsley, C, Mcauley, D, Blackwood, B, Denham, S, Worrall, R, Arshad, M, Isherwood, P, Khadjibaev, A, Sabirov, D, Rosstalnaya, A, Parpibaev, F, Sharipova, V, Guzman, C, Cha, Y, Lee, S, Tyagi, N, Rajput, R, Taneja, S, Singh, V, Sharma, S, Mittal, S, Rao, B, Ayachi, J, Fraj, N, Romdhani, S, Khedher, A, Meddeb, K, Sma, N, Azouzi, A, Bouneb, R, Chouchene, I, El Ghardallou, M, Boussarsar, M, Jennings, R, Walter, E, Ribeiro, J, Moniz, I, Marçal, R, Santos, A, Candeias, C, E. Silva, Z, Gomez, S, Nieto, O, Gonzalez, J, Cuellar, A, Mildh, H, Pettilä, V, Korhonen, A, Karlsson, S, Ala Kokko, T, Reinikainen, M, Vaara, S, Zaleska Kociecka, M, Grabowski, M, Dąbrowski, M, Wozniak, S, Piotrowska, K, Banaszewski, M, Imiela, J, Stepinska, J, Pérez, A, Ordoñez, P, Giribet, A, Cuervo, M, Cuervo, R, Esteban, M, Fraile, L, Mittelbrum, C, Albaiceta, G, Koeze, J, Keus, F, Dieperink, W, van der Horst, I, van Meurs, M, Zijlstra, J, Roberts, S, Caballero, C, Isgro, G, Hall, D, Beitland, S, Trøseid, A, Brusletto, B, Waldum Grevbo, B, Berg, J, Sunde, K, Huertas, D, Manzano, F, Quintana, M, Osuna, A, Santiago Ruiz, F, Rodríguez Mejías, C, Wangensteen, R, Jamaati, H, Hashemian, S, Abbasi, G, Khaloo, V, Tabei, S, Kafilzadeh, A, Bakhodaei, H, Diaz, J, Silva, R, Garcia, D, Luis, E, Gomez, M, Soriano, R, Gonzalez, P, Ibrahim, I, Rafik, M, Al Ansary, A, Algendi, M, Ali, A, Benten, D, Kluwe, J, Siedler, S, Adedugbe, I, Bird, G, Kennedy, R, Yugi, G, Haroon, B, Witter, T, Khaliq, W, Singer, M, Havaldar, A, Krishna, B, Sriram, S, Espinoza, E, Pozo, M, Edul, V, Furche, M, Motta, M, Vazquez, A, Birri, P, Dubin, A, Dogliotti, A, Ramos, A, Lovesio, C, Delile, E, Nevière, R, Thiébaut, P, Maupoint, J, Mulder, P, Coquerel, D, Renet, S, do Rego, J, Rieusset, J, Richard, V, Tamion, F, Andreis, D, Smit, B, Smulders, Y, van Straaten, H, Eringa, E, Man, A, Alegría, L, Soto, D, Luengo, C, Gomez, J, Jarufe, N, Bruhn, A, Castro, R, Kattan, E, Tapia, P, Rebolledo, R, Achurra, P, Ospina Tascón, G, Bakker, J, Hernández, G, Bertini, P, Guarracino, F, Baldassarri, R, Pinsky, M, Vera, M, Dreyse, J, Carpio, D, Henriquez, C, Gajardo, D, Bravo, S, Lee, M, Park, S, So, S, Kačar, M, Kačar, S, Uddin, I, Belhaj, A, Aydın, M, Avsec, D, Kapuağası, A, Kaymak, Ç, Kovach, L, Şencan, I, Meço, B, Özçelik, M, Ünal, N, Jenni Moser, B, Jeitziner, M, Galassi, M, Sales, F, de Moraes, K, Batista, C, Júnior, J, Marcari, T, Lobato, R, Castro, C, de Souza, L, Rodrigues, F, Correa, N, Pelegrini, A, Eid, R, Timenetsky, K, Cazati, D, Lobato, M, Diniz, P, Rocha, L, Cavalheiro, A, Lucinio, N, Santos, E, Norrenberg, M, Gleize, A, Simón, I, Valhonrat, I, Almudévar, P, Dávila, F, Rubio, J, Reina, Á, López, N, Pérez, M, Apolo, D, Villén, L, García, I, Izurieta, J, Guerrero, J, Calvert, S, Quint, M, Adeniji, K, Young, R, Shevill, D, Robertson, E, Garside, P, Isotti, P, De Vecchi, M, Perduca, A, Negro, A, Villa, G, Manara, D, Cabrini, L, Zangrillo, A, Frencken, J, van Baal, L, Donker, D, Horn, J, van der Poll, T, van Klei, W, Bonten, M, Menard, C, Kumar, A, Rimmer, E, Doucette, S, Turgeon, A, Houston, B, Houston, D, Zarychanski, R, Pinto, B, Carrara, M, Ferrario, M, Bendjelid, K, Nunes, J, Diaz, P, Silva, G, Escórcio, S, Chaves, S, Jardim, M, Fernandes, N, Câmara, M, Duarte, R, Pereira, C, Vieira, J, Nóbrega, J, de Oca Sandoval, M, Sánchez Rodríguez, A, Joya Galeana, J, Correa Morales, A, Camarena Alejo, G, Aguirre Sánchez, J, Franco Granillo, J, Soliman, M, Al Azab, A, El Hossainy, R, Nagy, H, Nirmalan, M, Crippa, I, Cavicchi, F, Chaari, A, Hakim, K, Hassanein, H, Etman, M, El Bahr, M, Bousselmi, K, Khalil, E, Kauts, V, Casey, W, Imahase, H, Sakamoto, Y, Yamada, K, Miike, T, Nagashima, F, Iwamura, T, Boscolo, A, Lucchetta, V, Piasentini, E, Bertini, D, Manesso, L, Spiezia, L, Simioni, P, Ori, C, Souza, R, Martins, A, Liberatore, A, Kang, Y, Nakamae, M, Koh, I, Hanslin, K, Wilske, F, Skorup, P, Sjölin, J, Lipcsey, M, Long, W, Zhen, C, Vakalos, A, Avramidis, V, Wu, S, Shyu, L, Li, C, Yu, C, Chen, H, Wang, C, Lin, K, Aray, Z, Gómez, C, Tejero, A, Monge, D, Losada, V, Tarancón, C, Cortés, S, Gutiérrez, A, Álvarez, T, Rouze, A, Jaffal, K, Six, S, Stolz, K, Cattoen, V, Arnal, J, Saoli, M, Novotni, D, Garnero, A, Becher, T, Buchholz, V, Schädler, D, Frerichs, I, Weiler, N, Eronia, N, Mauri, T, Gatti, S, Maffezzini, E, Bronco, A, Alban, L, Sasso, T, Marenghi, C, Grasselli, G, Pesenti, A, Bellani, G, Al Fares, A, Del Sorbo, L, Anwar, S, Facchin, F, Azad, S, Zamel, R, Cypel, M, Keshavjee, S, Durlinger, E, Spoelstra de Man, A, de Grooth, H, Straaten, H, Alfaro, M, Parrilla, F, Meli, A, Pellegrini, M, Rodriguez, N, Goyeneche, J, Morán, I, Aguirre, H, Mancebo, J, Heines, S, Strauch, U, Bergmans, D, Blankman, P, Shono, A, Hasan, D, Gommers, D, Chung, W, Jung, Y, Park, J, Sheen, S, Park, K, Worral, R, Larraza, S, Dey, N, Brohus, J, Winding, R, Volta, C, Ampatzidou, F, Vlachou, A, Kehagioglou, G, Karaiskos, T, Madesis, A, Mauromanolis, C, Michail, N, Drossos, G, Saraj, N, Rijkenberg, S, Feijen, H, Endeman, H, Donnelly, A, Morgan, E, Garrard, H, Buckley, H, Russell, L, Haase, N, Goh, C, Mouyis, K, Woodward, C, Halliday, J, Encina, G, Ros, J, Lagunes, L, Tabernero, J, Rello, J, Morente Constantin, E, Rivera Ginés, B, Colmenero Ruiz, M, Sanz, J, Simon, I, Valbuena, B, Pais, M, Ramalingam, S, Díaz, C, Fox, L, Santafe, M, Barba, P, García, M, Leal, S, Veganzones, J, Martínez, N, Moors, I, Mokart, D, Pène, F, Lambert, J, Mayaux, J, Vincent, F, Nyunga, M, Bruneel, F, Laisne, L, Rabbat, A, Lebert, C, Perez, P, Chaize, M, Renault, A, Meert, A, Hamidfar, R, Jourdain, M, Darmon, M, Schlemmer, B, Chevret, S, Lemiale, V, Azoulay, E, Benoit, D, Martins Branco, D, Sousa, M, Marum, S, Bouw, M, Galstyan, G, Makarova, P, Parovichnikova, E, Kuzmina, L, Troitskaya, V, Drize, N, Gemdzhian, E, Savchenko, V, Chao, H, Kılıc, E, Demiriz, B, Uygur, M, Sürücü, M, Cınar, K, Yıldırım, A, Kiss, K, Köves, B, Csernus, V, Molnár, Z, Ntantana, A, Matamis, D, Savvidou, S, Giannakou, M, Gouva, M, Nakos, G, Koulouras, V, Gaffney, S, Judge, C, Drew, T, Misran, H, Munshi, R, Mcgovern, L, Coyle, M, Dunne, L, Deasy, E, Lavin, P, Fahy, A, Darcy, D, Donnelly, M, Ismail, N, Hall, T, Wykes, K, Jack, J, Ngu, W, Morgan, P, Ruiz Ramos, J, Ramirez, P, Gordon, M, Villarreal, E, Frasquet, J, Poveda Andrés, J, Castellanos, A, Ijssennagger, C, Ten Hoorn, S, van Wijk, A, van den Broek, J, Tuinman, P, Elmenshawy, A, Hammond, B, Gibbon, G, Belcham, T, Burton, K, Taniguchi, L, Ramos, F, Momma, A, Martins Filho, A, Bartocci, J, Lopes, M, Sad, M, Rodrigues, C, Pires, E, Barreto, J, Duarte, S, Taba, S, Miglioranza, D, Gund, D, Lordani, C, Capuzzo, M, Corte, F, Terranova, S, Scaramuzzo, G, Fogagnolo, A, Bertacchini, S, Bellonzi, A, Ragazzi, R, Cruz, C, Nunes, A, Pereira, F, Aragão, I, Cardoso, A, Santos, C, Malheiro, M, Castro, H, Cardoso, T, Paratz, J, Kenardy, J, Comans, T, Coyer, F, Thomas, P, Boots, R, Pereira, N, Vilas Boas, A, Gomes, E, Torres, J, Carvalho, D, Molinos, E, Vales, C, Araújo, R, Karnatovskaia, L, Philbrick, K, Ognjen, G, Clark, M, Montero, R, Varas, J, Sánchez Elvira, L, Delgado, C, Díaz, P, Ruiz, B, Guerrero, A, Galache, J, Jiménez, R, Rebollo, S, Alejandro, O, Fernández, A, Moreno, S, Herrera, L, Ojados, A, Galindo, M, Murcia, J, Contreras, M, Sánchez Argente, S, Bonilla, Y, Rodríguez, M, Allegue, J, Cakin, Ö, Parlak, H, Kirca, H, Mutlu, F, Aydınlı, B, Cengiz, M, Ramazanoglu, A, Jung, E, Domenech, J, Montalvo, A, Chornet, T, Martinez, P, Ribas, M, Costa, R, Ortega, A, Forbes, C, Prescott, H, Lal, A, Khan, F, Dela Pena, E, Dizon, J, Wong, C, Garach, M, Romero, O, Puerta, R, Diaz, F, Bailon, A, Pinel, A, Maldonado, L, Kalaiselvan, M, Kumar, R, Renuka, M, De Rosa, S, Ferrari, F, Checcacci, S, Rigobello, A, Joannidis, M, Politi, F, Pellizzari, A, Bonato, R, Fernandez Carmona, A, Macias Guarasa, I, Gutierrez Rodriguez, R, Martinez Lopez, P, Diaz Castellanos, M, Arias Diaz, M, Aguilar Alonso, E, Nikandish, R, Artemenko, V, Budnyuk, A, Bassi, G, Senussi, T, Idone, F, Xiol, E, Travierso, C, Chiurazzi, C, Motos, A, Amaro, R, Hua, Y, Fernández Barat, L, Ranzani, O, Bobi, Q, Rigol, M, Youn, A, Hwang, J, Ossorio, M, Figueira, H, Oliveira, R, Mota, A, Kamp, O, Cruciger, O, Aach, M, Kaczmarek, C, Waydhas, C, Schildhauer, T, Hamsen, U, Camprubí Rimblas, M, Chimenti, L, Guillamat Prats, R, Lebouvier, T, Bringué, J, Tijero, J, Gómez, M, Blanch, L, Tagliabue, G, Ji, M, Jagers, J, Easton, P, Hong, J, Shin, M, Park, M, Pomprapa, A, Hofferberth, M, Russ, M, Braun, W, Walter, M, Francis, R, Lachmann, B, Leonhardt, S, Landaverde López, A, Canedo Castillo, N, Esquivel Chávez, A, Arvizu Tachiquín, P, Baltazar Torres, J, Cardoso, V, Krystopchuk, A, Castro, S, Melão, L, Firmino, S, Marreiros, A, Almaziad, S, Kubbara, A, Barnett, W, Nakity, R, Alamoudi, W, Altook, R, Tarazi, T, Fida, M, Safi, F, Assaly, R, Santini, A, Milesi, M, Maraffi, T, Pugni, P, Cavenago, M, Gattinoni, L, Protti, A, Perchiazzi, G, Borges, J, Bayat, S, Porra, L, Broche, L, Hedenstierna, G, Larsson, A, Roneus, A, Segelsjö, M, Vestito, M, Gremo, E, Nyberg, A, Castegren, M, Pikwer, A, Yoshida, T, Engelberts, D, Otulakowski, G, Katira, B, Post, M, Amato, M, Koch, N, Hoellthaler, J, Mair, S, Phillip, V, Beitz, A, Baladrón, V, Villarejo, P, Steenstra, R, Banierink, H, Hof, J, Hoekstra, M, Sterz, F, Horvatits, K, Herkner, H, Kott, M, Zitta, K, Brandt, B, Schildhauer, C, Elke, G, Hummitzsch, L, Albrecht, M, González, L, Alonso, D, Sánchez, R, Lucas, J, Ferlitsch, A, Fauler, G, Trauner, M, Pischke, S, Fischer, L, Thaiss, F, Koch, M, Bangert, K, Lohse, A, Nashan, B, Sterneck, M, Faenza, S, Siniscalchi, A, Pierucci, E, Mancini, E, Ricci, D, Gemelli, C, Cuoghi, A, Magnani, S, Atti, M, Sotos, F, Cánovas, J, López, A, Burruezo, A, Torres, D, Herrera Gutierrez, M, Barrueco Francioni, J, Arias Verdú, D, Lozano Saez, R, Quesada Garcia, G, Seller Pérez, G, Figueiredo, A, Anzola, Y, Pereira, R, Bento, L, Lai, M, Deiana, M, Seller Perez, G, Vardas, K, Ilia, S, Sertedaki, A, Charmadari, E, Stratakis, C, Briassouli, E, Goukos, D, Psarra, K, Botoula, E, Tsagarakis, S, Mageira, E, Routsi, C, Nanas, S, Campello, E, Radu, C, Su, H, Lam, Y, Willis, K, Pullar, V, Hubner, R, Tsang, J, de Guadiana Romualdo, L, Rebollo Acebes, S, Esteban Torrella, P, Jiménez Sánchez, R, Jiménez Santos, E, Ortín Freire, A, Hernando Holgado, A, Albaladejo Otón, M, Coelho, L, Rabello, L, Póvoa, P, Varis, E, Poukkanen, M, Jacob, S, Takala, J, Wilkman, E, Lundberg, O, Bergenzaun, L, Rydén, J, Rosenqvist, M, Melander, O, Chew, M, Kishihara, Y, Yasuda, H, Jimenez, R, Torrella, P, Fernandez, A, Sanchez, S, Ortin, A, Prats, R, Aguilera, E, Marti, D, Fernandez, L, Ferrer, M, Lanziotti, V, Pulcheri, L, Ribeiro, M, Barbosa, A, E. Silva, J, Soares, M, Marqués, M, Moreno, A, Pizarraya, A, Smani, Y, Connell, M, Zhang, L, Parker, R, Banerjee, I, Clermont, G, Norberg, E, Oras, J, Cuisinier, A, Maufrais, C, Payen, J, Nottin, S, Walther, G, Arib, S, Bilotta, F, Badenes, R, Rubulotta, F, Mirek, S, Monfort, B, Stazi, E, Roig, A, Magnoni, S, Marando, M, Pifferi, S, Conte, V, Ortolano, F, Carbonara, M, Bertani, G, Scola, E, Cadioli, M, Triulzi, F, Colombo, A, Stocchetti, N, Rotzel, H, Lázaro, A, Prada, D, Guimillo, M, Piqueras, C, Guia, J, Simon, M, Arizmendi, A, Carratalá, A, El Maraghi, S, Yehia, A, Bakry, M, Shoman, A, Backes, F, Bianchin, M, Vieira, S, de Souza, A, Backes, A, Klein, C, Arunkumar, A, Lozano, A, Gallaher, C, Cattlin, S, Gordon, S, Picard, J, Fontana, V, Bond, O, Nobile, L, Mrozek, S, Delamarre, L, Capilla, F, Al Saati, T, Fourcade, O, Dominguez Berrot, A, Gonzalez Vaquero, M, Vallejo Pascual, M, Gupta, D, Ivory, B, Chopra, M, Mccarthy, J, Felderhof, C, Macneil, C, Maggiorini, M, Duska, F, Fumis, R, Junior, J, Amarante, G, Skorko, A, Sanders, S, Aron, J, Kroll, R, Redfearn, C, Krishnan, P, Khalil, J, Kongpolprom, N, Gulia, V, Lourenço, E, Duro, C, Baptista, G, Alves, A, Arminda, B, Rodrigues, M, Hayward, J, Baldwin, F, Gray, R, Katinakis, P, Stijf, M, Ten Kleij, M, Jansen Frederiks, M, Broek, R, de Bruijne, M, Spronk, P, Sinha, K, Luney, M, Palmer, K, Keating, L, Abu Habsa, M, Bahl, R, Baskaralingam, N, Ahmad, A, Kanapeckaite, L, Bhatti, P, Glace, S, Jeyabraba, S, Lewis, H, Kostopoulos, A, Raja, M, West, A, Ely, A, Turkoglu, L, Zolfaghari, P, Baptista, J, Marques, M, Martins, P, Pimentel, J, Su, Y, Villacres, S, Stone, M, Parsikia, A, Medar, S, O'Dea, K, Porter, J, Tirlapur, N, Jonathan, J, Singh, S, Takata, M, Mcwhirter, E, Lyon, R, Hariz, M, Azmi, E, Alkhan, J, Movsisyan, V, Petrikov, S, Marutyan, Z, Aliev, I, Evdokimov, A, Antonucci, E, Merz, T, Hartmann, C, Calzia, E, Radermacher, P, Nußbaum, B, Huber Lang, M, Gröger, M, Svoren Jabalera, E, Davenport, E, Humburg, P, Knight, J, Hinds, C, Jun, I, Kim, W, Besch, G, Perrotti, A, Puyraveau, M, Baltres, M, Samain, E, Chocron, S, Pili Floury, S, Plata Menchaca, E, Sabater Riera, J, Estruch, M, Boza, E, Toscana Fernández, J, Bruguera Pellicer, E, Ordoñez Llanos, J, Pérez Fernández, X, Cavaleiro, P, Tralhão, A, Arrigo, M, Lopes, J, Lebrun, M, Cholley, B, Perezvela, J, Marinmateos, H, Rivera, J, Llorente, M, De Marcos, B, Fernandez, F, Laborda, C, Zamora, D, Delgado, J, Imperiali, C, Dastis, M, Górka, J, Górka, K, Iwaniec, T, Frołow, M, Polok, K, Fronczek, J, Kózka, M, Musiał, J, Szczeklik, W, Sileli, M, Moursia, C, Maleoglou, H, Leleki, K, Uz, Z, Ince, Y, Papatella, R, Bulent, E, De Mol, B, Vicka, V, Gineityte, D, Ringaitiene, D, Norkiene, I, Sipylaite, J, Möller, C, Thomas Rueddel, D, Vlasakov, V, Rochwerg, B, Theurer, P, Al Sibai, J, Camblor, P, Fernandez, P, Gala, J, Guisasola, J, Tamura, T, Miyajima, I, Yamashita, K, Yokoyama, M, Dalampini, E, Nastou, M, Baddour, A, Ignatiadis, A, Asteri, T, Hathorn, K, Purtle, S, Viana, M, Tonietto, T, Gross, L, Costa, V, Tavares, A, Lisboa, B, Moraes, R, Viana, L, Azevedo, M, Ceniccola, G, Pequeno, R, Holanda, T, Mendonça, V, Araújo, W, Carvalho, L, Segaran, E, Vickers, L, Brinchmann, K, Wignall, I, De Brito Ashurst, I, Del Olmo, R, Vaquerizo, C, Carreño, R, Gálvez, V, Kaminsky, G, Nieto, B, Fuentes, M, De la Torre, M, Torres, E, Alonso, A, Velayos, C, Saldaña, T, Escribá, A, Grip, J, Kölegård, R, Sundblad, P, Rooyackers, O, Naser, B, Jaziri, F, Jazia, A, Barghouth, M, Hentati, O, Skouri, W, El Euch, M, Mahfoudhi, M, Turki, S, Abdelghni, K, Abdallah, B, Maha, B, Lorente, M, Włudarczyk, A, Hałek, A, Bargouth, M, Bennasr, M, Abdelghani, K, Abdallah, T, Geenen, I, Parienti, J, Shum, H, King, H, Yan, W, Londoño, J, Cardenas, C, Pedrosa, M, Gubianas, C, Bertolin, C, Batllori, N, Sirvent, J, Mukhopadhyay, A, Chan, H, Kowitlawakul, Y, Remani, D, Leong, C, Henry, C, Puthucheary, Z, Mendsaikhan, N, Begzjav, T, Lundeg, G, Dünser, M, Welsh, S, Guerra, E, Zerpa, M, Zechner, F, Berdaguer, F, Risso Vazquez, A, Masevicius, F, Greaney, D, Magee, A, Fitzpatrick, G, Lugo Cob, R, Tejeda Huezo, B, Cano Oviedo, A, Aydogan, M, Togal, T, Taha, A, Chai, H, Kam, C, Razali, S, Sivasamy, V, Kuan, L, Morales, M, Pires, T, and Azevedo, L more...
Subjects: intracerebral haemorrhage in intensive care
Published: 2016

10. ESICM LIVES 2016: part two

Author: Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Meleti, D. E., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Prowle, J.R., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Quintard, H., Bouzat, P., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. J., Fortuit, C., Feuillet, F., Asehnoune, K., Marzorati, C., Spina, S., Scaravilli, V., Vargiolu, A., Riva, M., Giussani, C., Sganzerla, E., Citerio, G., Barbadillo, S., de Molina, F. J. González, Álvarez-Lerma, F., Rodríguez, A., Zakharkina, T., Martin-Loeches, I., Matamoros, S., Povoa, P., Torres, A., Kastelijn, J., Hofstra, J. J., de Jong, M., Schultz, M., Sterk, P., Artigas, A., Bos, L. J., Moreau, A. S., Salluh, J., Rodriguez, A., Nseir, S., de Jong, E., van Oers, J. A., Nijsten, M. W. N., de Lange, D. W., Bonvicini, D., Labate, D., Benacchio, L., Olivieri, A., Pizzirani, E., Lopez-Delgado, J. C., Gonzalez-Romero, M., Fuentes-Mila, V., Berbel-Franco, D., Romera-Peregrina, I., Martinez-Pascual, A., Perez-Sanchez, J., Abellan-Lencina, R., Ávila-Espinoza, R. E., Moreno-Gonzalez, G., Sbraga, F., Griffiths, S., Grocott, M. P. W., Doyle, J., Wilkerson, P., Soon, Y., Huddart, S., Dickinson, M., Riga, A., Zuleika, A., Miyamoto, K., Kawazoe, Y., Morimoto, T., Yamamoto, T., Fuke, A., Hashimoto, A., Koami, H., Beppu, S., Katayama, Y., Ito, M., Ohta, Y., Yamamura, H., Rygård, S. L., Holst, L B., Wetterslev, J., Johansson, P. I., Perner, A., Soliman, I. W., van Dijk, D., van Delden, J. J. M., Cremer, O. L., Slooter, A. J. C., McWilliams, D., Snelson, C., Neves, A. Das, Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Veronesi, M., Lischinsky, A., López, F. J. L., Mori, L. Benito, Plotnikow, G., Díaz, A., Giannasi, S., Hernandez, R., Krzisnik, L., Cecotti, C., Viola, L., Lopez, R., Sottile, J. P., Benavent, G., Estenssoro, E., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Chan, K. S., Roeker, L. E., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Weijs, P. J. M., Mogensen, K. M., Rawn, J. D., Robinson, M. K., Tang, Z., Qiu, C., Ouyang, B., Cai, C., Guan, X., Regueira, T., Cea, L., Carlos, S. Juan, Elisa, B., Puebla, C., Vargas, A., Poulsen, M. K., Thomsen, L. P., Kjærgaard, S., Rees, S. E., Karbing, D. S., Frank, S., Müller, M. C., Carbon, N. M., Skrypnikov, V., Pickerodt, P. A., Falk, R., Mahlau, A., Lee, A., Inglis, R., Morgan, R., Barker, G., Kamata, K., Abe, T., Saitoh, D., Tokuda, Y., Butler, M. B., Hwa, H. Tae, Gil, L. Jae, Vaquero, R. Hernández, Rodriguez-Ruiz, E., Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Thomas-Rüddel, D. O., Schwarzkopf, D., Fleischmann, C., Reinhart, K., Suwanpasu, S., Sattayasomboon, Y., Filho, N. M. Filgueiras, Oliveira, J. C. A., Ballalai, C. S., De Lucia, C. V., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Ramos, B. B., Ricaldi, E. F., Gomes, S. S., Wright, C., Docking, R. I., Doherty, P., Black, E., Stenhouse, P., Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Yatabe, T., Inoue, S., Sakaguchi, M., Egi, M., Abdelhamid, Y. Ali, Hokka, M., Mizobuchi, S., Plummer, M., Giersch, E., Summers, M., Hatzinikolas, S., Heller, S., Jones, K., Schweizer, R., Jacquet-Lagreze, M., Portran, P., Junot, S., Allaouchiche, B., Fellahi, J. L., Guerci, P., Ergin, B., Kapucu, A., Ince, C., Crisman, M., Shinotsuka, C. Righy, Fagnoul, D., Orbegozo, D., Preiser, J. C., Thooft, A., Brimioulle, S., Iwasaka, H., Tahara, S., Nagamine, M., Ichigatani, A., Cabrera, A. Rugerio, Zepeda, E. Monares, Granillo, J. Franco, Sánchez, J. S. Aguirre, Montoya, A. A. Tanaka, Montenegro, A. Pedraza, Blanco, G. A. Gálvez, Robles, C. M. Coronado, Drolz, A., Horvatits, T., Roedl, K., Rutter, K., Funk, G. C., Schneeweiss, B., Fuhrmann, V., Sabetian, G., Pooresmaeel, F., Ghaffaripour, S., Farbod, A., Tabei, H., Taheri, L., Anandanadesan, R., Metaxa, V., Teixeira, C., Pereira, S. M., Hernández-Marrero, P., Carvalho, A. S., Beckmann, M., Hartog, C. S., Raadts, A., Robertsen, A., Førde, R., Skaga, N. O., Helseth, E., Honeybul, S., Ho, K., Lopez, P. Martinez, Gonzalez, M. Nieto, Ortega, P. Nuevo, Sola, E. Camara, Spasova, T., Kopecky, O., Rusinova, K., Waldauf, P., Cepeplikova, Z., Domínguez, J. Palamidessi, Almudevar, P. Matia, Carmona, S. Alcántara, Muñoz, J. J. Rubio, Castañeda, D. Palacios, Abellán, A. Naharro, Villamizar, P. Rodríguez, Ramos, J. Veganzones, Pérez, L. Pérez, Lucendo, A. Pérez, Ejarque, M. Camós, Estella, A., Camps, V. Lopez, Martín, M. C., Masnou, N., Barbosa, S., Varela, A., Palma, I., Cristina, L., Nunes, E., Pereira, I., Campello, G., Granja, C., Pande, R., Pandey, M., Varghese, S., Chanu, M., Van Dam, M. J., Ter Braak, E. W. M. T., Gracia, M., Viciana, R., Recuerda, M., Fontaiña, L. Perez, Tharmalingam, B., Kovari, F., Rose, L., Mcginlay, M., Amin, R., Burns, K., Connolly, B., Hart, N., Jouvet, P., Katz, S., Leasa, D., Mawdsley, C., Mcauley, D., Blackwood, B., Denham, S., Worrall, R., Arshad, M., Isherwood, P., Khadjibaev, A., Sabirov, D., Rosstalnaya, A., Parpibaev, F., Sharipova, V., Blanco, G. A. Galvez, Guzman, C. I. Olvera, Cha, Y. S., Lee, S. J., Tyagi, N., Rajput, R. K., Taneja, S., Singh, V. K., Sharma, S. C., Mittal, S., Rao, B. K., Ayachi, J., Fraj, N., Romdhani, S., Khedher, A., Meddeb, K., Sma, N., Azouzi, A., Bouneb, R., Chouchene, I., El Ghardallou, M., Boussarsar, M., Jennings, R., Walter, E., Ribeiro, J. M., Moniz, I., Marçal, R., Santos, A. C., Candeias, C., e Silva, Z. Costa, Gomez, S. E. Zamora, Nieto, O. R. Perez, Gonzalez, J. A. Castanon, Cuellar, A. I. Vasquez, Mildh, H., Pettilä, V., Korhonen, A. M., Karlsson, S., Ala-Kokko, T., Reinikainen, M., Vaara, S. T., Zaleska-Kociecka, M., Grabowski, M., Dąbrowski, M., Wozniak, S., Piotrowska, K., Banaszewski, M., Imiela, J., Stepinska, J., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Koeze, J., Keus, F., Dieperink, W., van der Horst, I. C. C., van Meurs, M., Zijlstra, J. G., Roberts, S., Caballero, C. Hernandez, Isgro, G., Hall, D., Beitland, S., Trøseid, A.-M. S., Brusletto, B. S., Waldum-Grevbo, B. E., Berg, J. P., Sunde, K., Huertas, D. García, Manzano, F., Quintana, M. M. Jiménez, Osuna, A., Santiago-Ruiz, F., Rodríguez-Mejías, C., Wangensteen, R., Jamaati, H. R., Hashemian, S. M. R., Abbasi, G., Khaloo, V., Tabei, S. H.a., Kafilzadeh, A., Bakhodaei, H. Haddad, Diaz, J. A., Silva, R., Garcia, D. J., Luis, E., Gomez, M. N., Soriano, R., Gonzalez, P. L., Ibrahim, I. A., Rafik, M. M., Al-Ansary, A. M., Algendi, M. A., Ali, A. A., Benten, D., Kluwe, J., Siedler, S., Adedugbe, I., Bird, G. T., Kennedy, R. M., Sharma, S., Yugi, G., Haroon, B. A., Witter, T., Khaliq, W., Singer, M., Havaldar, A. A., Krishna, B., Sriram, S., Espinoza, E. D. Valenzuela, Pozo, M. O., Edul, V. S. Kanoore, Furche, M., Motta, M. F., Vazquez, A. Risso, Birri, P. N. Rubatto, Dubin, A., Dogliotti, A., Ramos, A., Lovesio, C., Delile, E., Nevière, R., Thiébaut, P.-A., Maupoint, J., Mulder, P., Coquerel, D., Renet, S., do Rego, J. C., Rieusset, J., Richard, V., Tamion, F., Andreis, D. T., Smit, B., Smulders, Y. M., van Straaten, H. M. Oudemans, Eringa, E. C., Man, A. M. E. Spoelstra-de, Alegría, L., Soto, D., Luengo, C., Gomez, J., Jarufe, N., Bruhn, A., Castro, R., Kattan, E., Tapia, P., Rebolledo, R., Achurra, P., Ospina-Tascón, G., Bakker, J., Hernández, G., Bertini, P., Guarracino, F., Baldassarri, R., Pinsky, M. R., Vera, M., Dreyse, J., Carpio, D., Henriquez, C., Gajardo, D., Bravo, S., Kim, S., Lee, M., Park, S. Y., So, S., Kačar, M. B., Kačar, S. M., Uddin, I., Belhaj, A. M., Aydın, M. A., Avsec, D., Kapuağası, A., Kaymak, Ç., Kovach, L., Şencan, İ., Meço, B., Özçelik, M., Ünal, N., Jenni-Moser, B., Jeitziner, M.-M., Galassi, M. S., Sales, F. L., de Moraes, K. C. L., Batista, C. L., Júnior, J. A. de Souza, Marcari, T. B., Lobato, R., Castro, C. S. A. A., de Souza, L. M., Rodrigues, F. F. P., Correa, N. G., Pelegrini, A. M., Eid, R. A. C., Timenetsky, K. T., Cazati, D., Lobato, M., Diniz, P. S., Rocha, L. L., Cavalheiro, A. M., Lucinio, N. M., Santos, E. R., Norrenberg, M., Gleize, A., Simón, I. Fernández, Valhonrat, I. Lipperheide, Almudévar, P. Matía, Dávila, F., Rubio, J. J., Ramos, A. J., Reina, Á. J. Roldán, López, N. Palomo, Pérez, M. Adriaensens, Apolo, D. X. Cuenca, Villén, L. Martín, López, F. M. Porras, García, I. Palacios, Izurieta, J. R. Naranjo, Guerrero, J. J. Egea, Calvert, S., Quint, M., Adeniji, K., Young, R., Shevill, D. D., Robertson, E., Garside, P., Isotti, P., De Vecchi, M. M., Perduca, A. E., Negro, A., Villa, G., Manara, D. F., Cabrini, L., Zangrillo, A., Frencken, J. F., van Baal, L., Donker, D. W., Horn, J., van der Poll, T., van Klei, W. A., Bonten, M. J. M., Menard, C. E., Kumar, A., Rimmer, E., Doucette, S., Turgeon, A. F., Houston, B. L., Houston, D. S., Zarychanski, R., Pinto, B. Bollen, Carrara, M., Ferrario, M., Bendjelid, K., Nunes, J., Diaz, P., Silva, G., Escórcio, S., Chaves, S., Jardim, M., Fernandes, N., Câmara, M., Duarte, R., Pereira, C. A., Vieira, J., Nóbrega, J. J., de Oca-Sandoval, M. A. Montes, Sánchez-Rodríguez, A., Joya-Galeana, J. G., Correa-Morales, A., Camarena-Alejo, G., Aguirre-Sánchez, J., Franco-Granillo, J., Soliman, M., Al Azab, A., El Hossainy, R., Nagy, H., Nirmalan, M., Crippa, I. A., Cavicchi, F. Zama, Chaari, A., Hakim, K. Abdel, Hassanein, H., Etman, M., El Bahr, M., Bousselmi, K., Khalil, E. S., Kauts, V., Casey, W. F., Imahase, H., Sakamoto, Y., Yamada, K. C., Miike, T., Nagashima, F., Iwamura, T., Boscolo, A., Lucchetta, V., Piasentini, E., Bertini, D., Manesso, L., Spiezia, L., Simioni, P., Ori, C., Souza, R. B., Martins, A. M., Liberatore, A. M. A., Kang, Y. R., Nakamae, M. N., Vieira, J. C. F., Koh, I. H. J., Hanslin, K., Wilske, F., Skorup, P., Sjölin, J., Lipcsey, M., Long, W. Jin, Zhen, C. Er, Vakalos, A., Avramidis, V., Wu, S. H., Shyu, L. J., Li, C. H., Yu, C. H., Chen, H. C., Wang, C. H., Lin, K. H., Aray, Z. E., Gómez, C. F., Tejero, A. P., Monge, D. D., Losada, V. M., Tarancón, C. M., Cortés, S. D., Gutiérrez, A. M., Álvarez, T. P., Rouze, A., Jaffal, K., Six, S., Stolz, K., Cattoen, V., Arnal, J. M., Saoli, M., Novotni, D., Garnero, A., Becher, T., Buchholz, V., Schädler, D., Frerichs, I., Weiler, N., Eronia, N., Mauri, T., Gatti, S., Maffezzini, E., Bronco, A., Alban, L., Sasso, T., Marenghi, C., Grasselli, G., Pesenti, A., Bellani, G., Al-Fares, A., Del Sorbo, L., Anwar, S., Facchin, F., Azad, S., Zamel, R., Ferguson, N., Cypel, M., Keshavjee, S., Durlinger, E., Spoelstra-de Man, A., de Grooth, H. J., Girbes, A., Straaten, H. Oudemans-van, Smulders, Y., Alfaro, M. A., Parrilla, F., Meli, A., Pellegrini, M., Rodriguez, N., Goyeneche, J. M., Morán, I., Aguirre, H., Mancebo, J., Heines, S. J. H., Strauch, U., Bergmans, D. C. J. J., Blankman, P., Shono, A., Hasan, D., Gommers, D., Chung, W. Y., Lee, K. S., Jung, Y. J., Park, J. H., Sheen, S. S., Park, K. J., Worral, R., Larraza, S., Dey, N., Brohus, J. B., Winding, R. W., Volta, C. A., Ampatzidou, F., Vlachou, A., Kehagioglou, G., Karaiskos, T., Madesis, A., Mauromanolis, C., Michail, N., Drossos, G., Saraj, N., Rijkenberg, S., Feijen, H. M., Endeman, H., Donnelly, A. A. J., Morgan, E., Garrard, H., Buckley, H., Russell, L., Haase, N., Goh, C., Mouyis, K., Woodward, C. L. N., Halliday, J., Encina, G. B., Ros, J., Lagunes, L., Tabernero, J., Bosch, F., Rello, J., Morente-Constantin, E., Rivera-Ginés, B., Colmenero-Ruiz, M., Sanz, J. García, Simon, I. Fernandez, Valbuena, B. Lobo, Carmona, S. Alcantara, Pais, M., Ramalingam, S., Díaz, C., Fox, L., Santafe, M., Barba, P., García, M., Leal, S., Pérez, M., Pérez, M. L. Pérez, Veganzones, J., Simón, I. Fernandez, Martínez, N., Moors, I., Mokart, D., Pène, F., Lambert, J., Mayaux, J., Vincent, F., Nyunga, M., Bruneel, F., Laisne, L., Rabbat, A., Lebert, C., Perez, P., Chaize, M., Renault, A., Meert, A. P., Hamidfar, R., Jourdain, M., Darmon, M., Schlemmer, B., Chevret, S., Lemiale, V., Azoulay, E., Benoit, D., Martins-Branco, D., Sousa, M., Marum, S., Bouw, M. J., Galstyan, G., Makarova, P., Parovichnikova, E., Kuzmina, L., Troitskaya, V., Drize, N., Gemdzhian, E., Savchenko, V., Chao, H. C., Kılıc, E., Demiriz, B., Uygur, M. L., Sürücü, M., Cınar, K., Yıldırım, A. E., Kiss, K., Köves, B., Csernus, V., Molnár, Z., Ntantana, A., Matamis, D., Savvidou, S., Giannakou, M., Gouva, M., Nakos, G., Koulouras, V., Gaffney, S., Docking, R., Judge, C., Drew, T., Misran, H., Munshi, R., McGovern, L., Coyle, M., Dunne, L., Deasy, E., Lavin, P., Fahy, A., Darcy, D. M., Donnelly, M., Ismail, N. H., Hall, T., Wykes, K., Jack, J., Ngu, W. C., Morgan, P., Ruiz-Ramos, J., Ramirez, P., Gordon, M., Villarreal, E., Frasquet, J., Poveda-Andrés, J. L., Castellanos, A., Ijssennagger, C. E., ten Hoorn, S., van Wijk, A., van den Broek, J. M., Tuinman, P. R., Elmenshawy, A. M., Hammond, B. D., Gibbon, G., Belcham, T., Burton, K., Taniguchi, L. U., Ramos, F. J. S., Momma, A. K., Martins-Filho, A. P. R., Bartocci, J. J., Lopes, M. F. D., Sad, M. H., Rodrigues, C. M., Pires, E. M. C., Vieira, J. M., Barreto, J., Duarte, S. T., Taba, S., Miglioranza, D., Gund, D. P., Lordani, C. F., Capuzzo, M., Corte, F. Dalla, Terranova, S., Scaramuzzo, G., Fogagnolo, A., Bertacchini, S., Bellonzi, A., Ragazzi, R., Cruz, C., Nunes, A., Pereira, F. Seabra, Aragão, I., Cardoso, A. F., Santos, C., Malheiro, M. J., Castro, H., Cardoso, T., Paratz, J., Kenardy, J., Comans, T., Coyer, F., Thomas, P., Boots, R., Pereira, N., Vilas-Boas, A., Gomes, E., Torres, J., Carvalho, D., Molinos, E., Vales, C., Araújo, R., Karnatovskaia, L., Philbrick, K., Ognjen, G., Clark, M., Montero, R. Molina, Varas, J. Luján, Sánchez-Elvira, L. Alcázar, Delgado, C. Pintado, Díaz, P. Villa, Ruiz, B. Llorente, Guerrero, A. Pardo, Galache, J. A. Cambronero, Jiménez, R., Rebollo, S., Alejandro, O., Fernández, A., Moreno, S., Herrera, L., Ojados, A., Galindo, M., Murcia, J., Contreras, M., Sánchez-Argente, S., Bonilla, Y., Rodríguez, M. D., Allegue, J. M., Cakin, Ö., Parlak, H., Kirca, H., Mutlu, F., Aydınlı, B., Cengiz, M., Ramazanoglu, A., Jung, E.-J., Oh, S.-Y., Domenech, J. Cebrián, Montalvo, A. Pinos, Chornet, T. Ciges, Martinez, P. Concha, Ribas, M. Piñol, Costa, R. Gimeno, Ortega, A. Castellanos, Forbes, C., Prescott, H., Lal, A., Khan, F. A., Dela Pena, E. G., Dizon, J. S., Perez, P. P. P., Wong, C. M. J., Garach, M. Muñoz, Romero, O. Moreno, Puerta, R. Ramirez, Diaz, F. Acosta, Bailon, A. M. Perez, Pinel, A. Carranza, Maldonado, L. Peñas, Kalaiselvan, M. S., kumar, R. L. Siva, Renuka, M. K., Kumar, A. S. Arun, De Rosa, S., Ferrari, F., Checcacci, S. Carboni, Rigobello, A., Joannidis, M., Politi, F., Pellizzari, A., Bonato, R., Fernandez-Carmona, A., Macias-Guarasa, I., Gutierrez-Rodriguez, R., Martinez-Lopez, P., Diaz-Castellanos, M. A., Arias-Diaz, M., Aguilar-Alonso, E., Nikandish, R. N., Artemenko, V., Budnyuk, A., Bassi, G. Li, Senussi, T., Idone, F., Xiol, E. Aguilera, Travierso, C., Chiurazzi, C., Motos, A., Amaro, R., Hua, Y., Fernández-Barat, L., Ranzani, O. T., Bobi, Q., Rigol, M., Youn, A., Hwang, J. Gyung, Ossorio, M. E. Yuste, Figueira, H., Oliveira, R., Mota, A., Kamp, O., Cruciger, O., Aach, M., Kaczmarek, C., Waydhas, C., Schildhauer, T. A., Hamsen, U., Camprubí-Rimblas, M., Chimenti, L., Guillamat-Prats, R., Lebouvier, T., Bringué, J., Tijero, J., Gómez, M. N., Blanch, L., Tagliabue, G., Ji, M., Jagers, J. V. Suneby, Easton, P. A., Martins, A. M. C. R. P. F., Hong, J. Y., Shin, M. H., Park, M. S., Pomprapa, A., Hofferberth, M. B. T., Russ, M., Braun, W., Walter, M., Francis, R., Lachmann, B., Leonhardt, S., Landaverde-López, A., Canedo-Castillo, N. A., Esquivel-Chávez, A., Arvizu-Tachiquín, P. C., Baltazar-Torres, J. A., Cardoso, V., Krystopchuk, A., Castro, S., Melão, L., Firmino, S., Marreiros, A., Almaziad, S., Kubbara, A., Barnett, W., Nakity, R., Alamoudi, W., Altook, R., Tarazi, T., Fida, M., Safi, F., Assaly, R., Santini, A., Milesi, M., Maraffi, T., Pugni, P., Cavenago, M., Gattinoni, L., Protti, A., Perchiazzi, G., Borges, J. B., Bayat, S., Porra, L., Broche, L., Hedenstierna, G., Larsson, A., Roneus, A., Segelsjö, M., Vestito, M. C., Gremo, E., Nyberg, A., Castegren, M., Pikwer, A., Yoshida, T., Engelberts, D., Otulakowski, G., Katira, B., Post, M., Brochard, L., Amato, M. B. P., Koch, N., Hoellthaler, J., Mair, S., Phillip, V., Beitz, A., Baladrón, V., Villarejo, P., Steenstra, R. J., Banierink, H., Hof, J., van der Horst, I. C., Nijsten, M. W., Hoekstra, M., Sterz, F., Horvatits, K., Herkner, H., Kott, M., Zitta, K., Brandt, B., Schildhauer, C., Elke, G., Hummitzsch, L., Albrecht, M., González, L. Rey, Alonso, D. Cabestrero, Sánchez, R. de Pablo, Lucas, J. Higuera, Ferlitsch, A., Fauler, G., Trauner, M., Pischke, S., Fischer, L., Thaiss, F., Koch, M., Bangert, K., Lohse, A. W., Nashan, B., Sterneck, M., Faenza, S., Siniscalchi, A., Pierucci, E., Mancini, E., Ricci, D., Gemelli, C., Cuoghi, A., Magnani, S., Atti, M., Sotos, F., Cánovas, J., López, A., Burruezo, A., Torres, D., Herrera-Gutierrez, M. E., Barrueco-Francioni, J., Arias-Verdú, D., Lozano-Saez, R., Quesada-Garcia, G., Seller-Pérez, G., Figueiredo, A., Anzola, Y., Pereira, R., Bento, L., Lai, M., Deiana, M., Seller-Perez, G., Vardas, K., Ilia, S., Sertedaki, A., Charmadari, E., Stratakis, C. A., Briassouli, E., Goukos, D., Psarra, K., Botoula, E., Tsagarakis, S., Mageira, E., Routsi, C., Nanas, S., Campello, E., Radu, C. M., Su, H., Lam, Y. M., Willis, K., Pullar, V., Hubner, R. P., Tsang, J. L., de Guadiana-Romualdo, L. García, Rebollo-Acebes, S., Esteban-Torrella, P., Jiménez-Sánchez, R., Jiménez-Santos, E., Ortín-Freire, A., Hernando-Holgado, A., Albaladejo-Otón, M. D., Coelho, L., Rabello, L., Póvoa, P., Varis, E., Poukkanen, M., Jacob, S., Takala, J., Wilkman, E., Lundberg, O. H. M., Bergenzaun, L., Rydén, J., Rosenqvist, M., Melander, O., Chew, M. S., Kishihara, Y., Yasuda, H., Jimenez, R., Torrella, P. Esteban, Fernandez, A., Sanchez, S., Ortin, A., Prats, R. Guillamat, Aguilera, E., Marti, D., Fernandez, L., Ferrer, M., Lanziotti, V. S., Pulcheri, L., Ribeiro, M. O., Barbosa, A. P., e Silva, J. R. Lapa, Soares, M., Salluh, J. I. F., Marqués, M. Gil, Moreno, A. Puppo, Pizarraya, A. Gutierrez, Diaz, J. Pachón, Smani, Y., Connell, M. Mc, Zhang, L. A., Parker, R. S., Banerjee, I., Clermont, G., Norberg, E., Oras, J., Cuisinier, A., Maufrais, C., Payen, J. F., Nottin, S., Walther, G., Arib, S., Bilotta, F., Badenes, R., Rubulotta, F., Mirek, S., Monfort, B., Stazi, E., Roig, A. Lozano, Magnoni, S., Marando, M., Pifferi, S., Conte, V., Ortolano, F., Carbonara, M., Bertani, G., Scola, E., Cadioli, M., Triulzi, F., Colombo, A., Stocchetti, N., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Guimillo, M. Rodriguez, Piqueras, C. Sanchís, Guia, J. Romero, Simon, M. García, Arizmendi, A. Mesejo, Carratalá, A., El Maraghi, S., Yehia, A., Bakry, M., Shoman, A., Backes, F. N., Bianchin, M. M., Vieira, S. R. R., de Souza, A., Backes, A. N., Klein, C., Arunkumar, A. S., Lozano, A., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kongpolprom, N., Gulia, V., Lourenço, E., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Calzia, E., Radermacher, P., Nußbaum, B., Huber-Lang, M., Gröger, M., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Dastis, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Sileli, M., Moursia, C., Maleoglou, H., Leleki, K., Uz, Z., Ince, Y., Papatella, R., Bulent, E., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Tamura, T., Miyajima, I., Yamashita, K., Yokoyama, M., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Hathorn, K. E., Purtle, S. W., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Lorente, M., Włudarczyk, A., Hałek, A., Bargouth, M., Bennasr, M., Abdelghani, K. Ben, Abdallah, T. Ben, Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Welsh, S. P., Guerra, E., Zerpa, M. C. l., Zechner, F., Berdaguer, F., Risso-Vazquez, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Morales, M. A. Lopez, Pires, T., and Azevedo, L. C. P. more...
Subjects: Meeting Abstracts
Abstract: Introduction In addition to systemic hemodynamics, the management\ud of neurocritically ill patients is often informed by neuromonitoring. In\ud the absence of high-level evidence clinicians are often guided by personal\ud and local expertise. Little is known about practices as they pertain\ud to the use of such monitoring in patients with acute brain injury (ABI).\ud Objectives To investigate practices in bedside monitoring for ABI patients.\ud Particularly interested in differences among “neurointensivists”\ud (NIs; defined here as intensivists whose clinical practice is comprised\ud > 1/3 by neurocritical care) and other intensivists (OIs). Also, to\ud explore patterns specific to traumatic brain injury (TBI) and subarachnoid\ud hemorrhage (SAH), as well as preferences and availability of\ud particular technologies/devices.\ud Methods Electronic survey of 22 items including two case-based scenarios;\ud endorsed by SCCM (9,000 recipients) and ESICM (on-line\ud newsletter) in 2013. A sample size of 370 was calculated based on a\ud population of 10,000 physician members, a 5 % margin error, and\ud 95 % confidence interval. We summarized results using descriptive\ud statistics (proportions with 95 % confidence intervals). A chi-square\ud test was used to compare proportions of responses between NIs and\ud OIs with a significance p < 0.05.\ud Results There were 655 responders (66 % completion rate); 422(65 %)\ud were classified as OIs and 226(35 %) as NIs. More NIs follow\ud hemodynamic protocols for neurocritically-ill patients (56 % vs. 43 %, p\ud 0.001), in TBI (44.5 % vs. 33.3 %, p 0.007), and in SAH (38.1 % vs. 21.3 %,\ud p < 000.1). For delayed cerebral ischemia (DCI), more NIs target cardiac\ud index (CI) (35 % vs. 21 %, p 0.0001), and fluid responsiveness (62 % vs.\ud 53 %, p 0.03), use more bedside ultrasound (BUS) (42 % vs. 29 %, p\ud 0.005) and arterial waveform analysis (40 % vs. 29 %, p 0.02). For DCI\ud neuromonitoring, NIs use more angiography (57 % vs. 43 %, p 0.004),\ud TCD (46 % vs. 38 %, p 0.0001), and CTP (32 % vs.16 %, p 0.0001). For\ud CPP optimization in TBI, NIs use more arterial waveform analysis (45 %\ud vs. 35 %, p 0.019), and BUS (37 % vs. 27.7 %, p 0.023), while more OIs\ud monitor mixed venous oxygen saturation (54.1 % vs. 45 %, p 0.045). For\ud TBI neuromonitoring, NIs use more PbtO2 (28 % vs. 10 %, p 0.0001). In\ud the case scenario of raised ICP/low PbtO2, most employ analgosedation\ud (47 %) and osmotherapy (38 %). Fewer make use of preserved pressure\ud reactivity, particularly OIs (vasopressor use 23 % vs. 34 %, p 0.014).\ud Conclusions There is large heterogeneity in the use of monitoring protocols,\ud variables, and technologies/devices. “Neurointensivists” not only\ud employ more neuromonitoring but also more hemodynamic monitoring\ud in patients with acute brain injury. ICP/CPP remain the most commonly\ud followed neuro-variables in TBI patients, with low use of other\ud brain-physiology parameters, sugg more...
Published: 2016

11. High Functional Stability of a Low-cost HBV DNA qPCR Primer Pair and Plasmid Standard

Author: Jorge Aguiar, Canales E, G. I. Garcia, Julio C Aguilar, Gerardo Guillén, Regla Estrada, Morán I, Angel Silva J, Gell O, Muzio, Yamila Leon, and Eduardo Pentón
Subjects: 0301 basic medicine, Hepatitis B virus, Laboratory research, medicine.disease_cause, Plasmid, law.invention, 03 medical and health sciences, chemistry.chemical_compound, law, Oligonucleotide, medicine, Quantitative PCR, Polymerase chain reaction, business.industry, Cycles threshold, Molecular biology, Primer, Functional stability, 030104 developmental biology, Real-time polymerase chain reaction, chemistry, Primer (molecular biology), business, Viral load, DNA, Research Article
Abstract: Aim We studied the functional stability of a primer pair and the standard curve based on a plasmid carrying full-length HBV genome, from a novel low-cost real-time quantitative polymerase chain reaction (qPCR) assay. The assay was developed at the Center for Genetic Engineering and Biotechnology (CIGB) in Havana, to quantify the serum hepatitis B virus (HBV) DNA from chronic HBV-infected (CHB) patients. Materials and methods In-house generated oligonucleotides and plasmids were incubated at 37°C during 1 month and compared with the same materials incubated at –20, 4, and 25°C during the same time in qPCR experiments. Results This work shows that the oligonucleotide pair and the plasmid for the quantitative standard curve are functionally stable in severe temperature conditions during 1 month. Polymerase chain reaction amplification with both materials after its incubation 30 days at 37°C produced similar cycle threshold (CT) values and similar degree of sample quantifications compared with the same materials preserved using the conventional storage conditions at –20°C. Conclusion These results are indicative of the robustness of this low-cost qPCR system for HBV DNA quantification. These results also support that this qPCR assay can be used as a low-cost technology in clinical studies to monitor the viral load changes of serum HBV DNA of CHB patients, which could be used by poor people of third world countries, where there are frequent blackouts and temperature changes that can hinder the primer and plasmid stability. How to cite this article Aguiar J, García G, León Y, Canales E, Silva JA, Gell O, Estrada R, Morán I, Muzio V, Guillén G, Pentón E, Aguilar JC. High Functional Stability of a Low-cost HBV DNA qPCR Primer Pair and Plasmid Standard. Euroasian J Hepato-Gastroenterol 2016;6(1):19-24. more...
Published: 2015

12. Pancreatic β-cell transcriptome analysis reveals dynamically regulated, tissue-specific and diabetes-associated long non-coding RNAs

Author: Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García Hurtado J, Rodríguez Seguí S, Pasquali P, Sauty Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins, T, Gmyr v, Pattou F, Kerr Conte J, Berney T, Hanley L, Gloyn A, Sussel L, Langman L, Braymnan KL, Sander M, McCarthy M, Ravassard P, Ferrer J., PIEMONTI , LORENZO, Morán, I, Akerman, I, van de Bunt, M, Xie, R, Benazra, M, Nammo, T, Arnes, L, Nakić, N, García Hurtado, J, Rodríguez Seguí, S, Pasquali, P, Sauty Colace, C, Beucher, A, Scharfmann, R, van Arensbergen, J, Johnson, Pr, Berry, A, Lee, C, Harkins, T, Gmyr, V, Pattou, F, Kerr Conte, J, Piemonti, Lorenzo, Berney, T, Hanley, L, Gloyn, A, Sussel, L, Langman, L, Braymnan, Kl, Sander, M, Mccarthy, M, Ravassard, P, and Ferrer, J. more...
Published: 2012

13. TOPONÍMIA ANTIGA DE L’HOSPITALET DE LLOBREGAT

Author: Josep Morán i Ocerinjauregui
Subjects: Cultural Studies, Linguistics and Language, History, Literature and Literary Theory, Language and Linguistics
Published: 1999
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14. Long COVID symptoms in Israeli children with and without a history of SARS-CoV-2 infection: a cross-sectional study

Author: Robert Hoffman, Zachi Grossman, Joseph Azuri, Limor Adler, Moran Israel, Ilan Yehoshua, Arnon Shahar, and Miri Mizrahi Reuveni
Subjects: Medicine
Abstract: Objectives To estimate the prevalence of long COVID symptoms in children with and without a history of SARS-CoV-2 infection and to evaluate factors associated with long COVID.Design A nationwide cross-sectional study.Setting Primary care.Participants 3240 parents of children aged 5–18 with and without SARS-CoV-2 infection completed an online questionnaire (11.9% response rate); 1148 and 2092 with/without a history of infection, respectively.Primary and secondary outcome measures Primary outcome was the prevalence of long COVID symptoms in children with/without a history of infection. Secondary outcomes were the factors associated with the presence of long COVID symptoms and with failure to return to baseline health status in children with a history of infection including gender, age, time from illness, symptomatic illness and vaccine status.Results Most long COVID symptoms were more prevalent in children with a history of SARS-CoV-2 infection: headaches (211 (18.4%) vs 114 (5.4%), p more...
Published: 2023
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15. Les suffixes dans la formation des noms d’origine en catalan

Author: Josep Morán i Ocerinjauregui
Published: 2002
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16. Bioavailability of four brands of phenytoin.

Author: Cid, E., Morán, I., Monaris, M., Lasserre, Ch., and Vidal, V.
Published: 1981
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17. ESICM LIVES 2016: part three : Milan, Italy. 1-5 October 2016

Author: Velasquez, T., Mackey, G., Lusk, J., Kyle, Ug, Fontenot, T., Marshall, P., Shekerdemian, Ls, Coss-Bu, Ja, Nishigaki, A., Yatabe, T., Tamura, T., Yamashita, K., Yokoyama, M., Ruiz-Rodriguez, Jc, Encina, B., Belmonte, R., Troncoso, I., Tormos, P., Riveiro, M., Baena, J., Sanchez, A., Bañeras, J., Cordón, J., Duran, N., Ruiz, A., Caballero, J., Nuvials, X., Riera, J., Serra, J., Rutten, Am, Ieperen, Sn, Kinderen, Ep, Logten, T., Kovacikova, L., Skrak, P., Zahorec, M., Akcan-Arikan, A., Silva, Jc, Goldsworthy, M., Wood, D., Harrison, D., Parslow, R., Davis, P., Pappachan, J., Goodwin, S., Ramnarayan, P., Chernyshuk, S., Yemets, H., Zhovnir, V., Pulitano, Sm, Rosa, S., Mancino, A., Villa, G., Tosi, F., Franchi, P., Conti, G., Patel, B., Khine, H., Shah, A., Sung, D., Singer, L., Haghbin, S., Inaloo, S., Serati, Z., Idei, M., Nomura, T., Yamamoto, N., Sakai, Y., Yoshida, T., Matsuda, Y., Yamaguchi, Y., Takaki, S., Yamaguchi, O., Goto, T., Longani, N., Medar, S., Abdel-Aal, Ir, El Adawy, As, Mohammed, Hm, Mohamed, An, Parry, Sm, Knight, Ld, Denehy, L., Morton, N., Baldwin, Ce, Sani, D., Kayambu, G., Da Silva, Vz, Phongpagdi, P., Puthucheary, Za, Granger, Cl, Rydingsward, Je, Horkan, Cm, Christopher, Kb, Mcwilliams, D., Jones, C., Reeves, E., Atkins, G., Snelson, C., Aitken, Lm, Rattray, J., Kenardy, J., Hull, Am, Ullman, A., Le Brocque, R., Mitchell, M., Davis, C., Macfarlane, B., Azevedo, Jc, Rocha, Ll, Freitas, Ff, Cavalheiro, Am, Lucinio, Nm, Lobato, Ms, Ebeling, G., Kraegpoeth, A., Laerkner, E., Brito-Ashurst, I., White, C., Gregory, S., Forni, Lg, Flowers, E., Curtis, A., Wood, Ca, Siu, K., Venkatesan, K., Muhammad, Jb, Ng, L., Seet, E., Baptista, N., Escoval, A., Tomas, E., Agrawal, R., Mathew, R., Varma, A., Dima, E., Charitidou, E., Perivolioti, E., Pratikaki, M., Vrettou, C., Giannopoulos, A., Zakynthinos, S., Routsi, C., Atchade, E., Houzé, S., Jean-Baptiste, S., Thabut, G., Genève, C., Tanaka, S., Lortat-Jacob, B., Augustin, P., Desmard, M., Montravers, P., Molina, Fj, Barbadillo, S., Alejandro, R., Álvarez-Lerma, F., Vallés, J., Catalán, Rm, Palencia, E., Jareño, A., Granada, Rm, Ignacio, Ml, Getgag, Working Group, Cui, N., Liu, D., Wang, H., Su, L., Qiu, H., Li, R., Jaffal, K., Rouzé, A., Poissy, J., Sendid, B., Nseir, S., Paramythiotou, E., Rizos, M., Frantzeskaki, F., Antoniadou, A., Vourli, S., Zerva, L., Armaganidis, A., Gottlieb, J., Greer, M., Wiesner, O., Martínez, M., Acuña, M., Rello, J., Welte, T., Mignot, T., Soussi, S., Dudoignon, E., Ferry, A., Chaussard, M., Benyamina, M., Alanio, A., Touratier, S., Chaouat, M., Lafaurie, M., Mimoun, M., Mebazaa, A., Legrand, M., Sheils, Ma, Patel, C., Mohankumar, L., Akhtar, N., Noriega, Sk, Aldana, Nn, León, Jl, Baquero, Jd, Bernal, Ff, Ahmadnia, E., Hadley, Js, Millar, M., Hall, D., Hewitt, H., Yasuda, H., Sanui, M., Komuro, T., Kawano, S., Andoh, K., Yamamoto, H., Noda, E., Hatakeyama, J., Saitou, N., Okamoto, H., Kobayashi, A., Takei, T., Matsukubo, S., Jseptic, Clinical Trial Group, Rotzel, Hb, Lázaro, As, Prada, Da, Gimillo, MR, Barinas, Od, Cortes, Ml, Franco, Jf, Roca, Jm, Carratalá, A., Gonçalves, B., Turon, R., Mendes, A., Miranda, F., Mata, Pj, Cavalcanti, D., Melo, N., Lacerda, P., Kurtz, P., Righy, C., Rosario, Le, Lesmes, Sp, Romero, Jc, Herrera, An, Pertuz, Ed, Sánchez, Mj, Sanz, Er, Hualde, Jb, Hernández, Aa, Irazabal, Jm, Spatenkova, V., Bradac, O., Suchomel, P., Urli, T., Lazzeri, Eh, Aspide, R., Zanello, M., Perez-Borrero, L., Garcia-Alvarez, Jm, Arias-Verdu, Md, Aguilar-Alonso, E., Rivera-Fernandez, R., Mora-Ordoñez, J., La Fuente-Martos, C., Castillo-Lorente, E., Guerrero-Lopez, F., Ramírez, Jr, León, Jp, Navarro-Guillamón, L., Cordovilla-Guardia, S., Iglesias-Santiago, A., Guerrero-López, F., Fernández-Mondéjar, E., Vidal, A., Perez, M., Juez, A., Arias, N., Colino, L., Perez, Jl, Pérez, H., Calpe, P., Alcala, Ma, Robaglia, D., Perez, C., Lan, Sk, Cunha, Mm, Moreira, T., Santos, F., Lafuente, E., Fernandes, Mj, Silva, Jg, Echeverría, Jg, Podlepich, V., Sokolova, E., Alexandrova, E., Lapteva, K., Shuinotsuka, C., Rabello, L., Vianna, G., Reis, A., Cairus, C., Salluh, J., Bozza, F., Torres, Jc, Araujo, Nj, García-Olivares, P., Keough, E., Dalorzo, M., Tang, Lk, Sousa, I., Díaz, M., Marcos-Zambrano, Lj, Guerrero, Je, Gomez, Se, Lopez, Gd, Cuellar, Ai, Nieto, Or, Gonzalez, Ja, Bhasin, D., Rai, S., Singh, H., Gupta, O., Bhattal, Mk, Sampley, S., Sekhri, K., Nandha, R., Aliaga, Fa, Olivares, F., Appiani, F., Farias, P., Alberto, F., Hernández, A., Pons, S., Sonneville, R., Bouadma, L., Neuville, M., Mariotte, E., Radjou, A., Lebut, J., Chemam, S., Voiriot, G., Dilly, Mp, Mourvillier, B., Dorent, R., Nataf, P., Wolff, M., Timsit, Jf, Ediboglu, O., Ataman, S., Ozkarakas, H., Kirakli, C., Vakalos, A., Avramidis, V., Obukhova, O., Kurmukov, Ia, Kashiya, S., Golovnya, E., Baikova, Vn, Ageeva, T., Haritydi, T., Kulaga, Ev, Rios-Toro, Jj, Lopez-Caler, C., Rodriguez-Fernandez, S., Sanchez-Orézzoli, Mg, Martin-Gallardo, F., Nikhilesh, J., Joshi, V., Villarreal, E., Ruiz, J., Gordon, M., Quinza, A., Gimenez, J., Piñol, M., Castellanos, A., Ramirez, P., Jeon, Yd, Jeong, Wy, Kim, Mh, Jeong, Iy, Ahn, My, Ahn, Jy, Han, Sh, Choi, Jy, Song, Yg, Kim, Jm, Ku, Ns, Shah, H., Kellner, F., Rezai, F., Mistry, N., Yodice, P., Ovnanian, V., Fless, K., Handler, E., Alejos, Rm, Romeu, Jd, Antón, Dg, Quinart, A., Martí, At, Laura Navarro Guillamon, Lobo-Civico, A., Ventura-Rosado, A., Piñol-Tena, A., Pi-Guerrero, M., Paños-Espinosa, C., Peralvo-Bernat, M., Marine-Vidal, J., Gonzalez-Engroba, R., Montesinos-Cerro, N., Treso-Geira, M., Valeiras-Valero, A., Martinez-Reyes, L., Sandiumenge, A., Jimenez-Herrera, Mf, Capcri, Study, Helyar, S., Riozzi, P., Noon, A., Hallows, G., Cotton, H., Keep, J., Hopkins, Pa, Taggu, A., Renuka, S., Sampath, S., Rood, Pj, Frenzel, T., Verhage, R., Bonn, M., Pickkers, P., Hoeven, Jg, Den Boogaard, M., Corradi, F., Melnyk, L., Moggia, F., Pienovi, R., Adriano, G., Brusasco, C., Mariotti, L., Lattuada, M., Bloomer, Mj, Coombs, M., Ranse, K., Endacott, R., Maertens, B., Blot, K., Blot, S., Amerongen, Mp, Heiden, Es, Twisk, Jw, Girbes, Ar, Spijkstra, Jj, Bell, C., Peters, K., Feehan, A., Churchill, K., Hawkins, K., Brook, R., Paver, N., Maistry, N., Wijk, A., Rouw, N., Galen, T., Evelein-Brugman, S., Krishna, B., Putzu, A., Fang, M., Berto, Mb, Belletti, A., Cassina, T., Cabrini, L., Mistry, M., Alhamdi, Y., Welters, I., Abrams, St, Toh, Ch, Han, Hs, Gil, Em, Lee, Ds, Park, Cm, Winder-Rhodes, S., Lotay, R., Doyle, J., Ke, Mw, Huang, Wc, Chiang, Ch, Hung, Wt, Cheng, Cc, Lin, Kc, Lin, Sc, Chiou, Kr, Wann, Sr, Shu, Cw, Kang, Pl, Mar, Gy, Liu, Cp, Dubó, S., Aquevedo, A., Jibaja, M., Berrutti, D., Labra, C., Lagos, R., García, Mf, Ramirez, V., Tobar, M., Picoita, F., Peláez, C., Carpio, D., Alegría, L., Hidalgo, C., Godoy, K., Bakker, J., Hernández, G., Sadamoto, Y., Katabami, K., Wada, T., Ono, Y., Maekawa, K., Hayakawa, M., Sawamura, A., Gando, S., Marin-Mateos, H., Perez-Vela, Jl, Garcia-Gigorro, R., Peiretti, Ma, Lopez-Gude, Mj, Chacon-Alves, S., Renes-Carreño, E., Montejo-González, Jc, Parlevliet, Kl, Touw, Hr, Beerepoot, M., Boer, C., Elbers, Pw, Tuinman, Pr, Abdelmonem, Sa, Helmy, Ta, El Sayed, I., Ghazal, S., Akhlagh, Sh, Masjedi, M., Hozhabri, K., Kamali, E., Zýková, I., Paldusová, B., Sedlák, P., Morman, D., Youn, Am, Ohta, Y., Sakuma, M., Bates, D., Morimoto, T., Su, Pl, Chang, Wy, Lin, Wc, Chen, Cw, Facchin, F., Zarantonello, F., Panciera, G., Cassai, A., Venrdramin, A., Ballin, A., Tonetti, T., Persona, P., Ori, C., Del Sorbo, L., Rossi, S., Vergani, G., Cressoni, M., Chiumello, D., Chiurazzi, C., Brioni, M., Algieri, I., Guanziroli, M., Colombo, A., Tomic, I., Crimella, F., Carlesso, E., Gasparovic, V., Gattinoni, L., Neto, As, Schmidt, M., Pham, T., Combes, A., Abreu, Mg, Pelosi, P., Schultz, Mj, Prove, Reva Research Network And The Network Investigators, Katira, Bh, Engelberts, D., Giesinger, Re, Ackerley, C., Zabini, D., Otulakowski, G., Post, M., Kuebler, Wm, Mcnamara, Pj, Kavanagh, Bp, Pirracchio, R., Rigon, MR, Carone, M., Chevret, S., Annane, D., Eladawy, S., El-Hamamsy, M., Bazan, N., Elgendy, M., Pascale, G., Vallecoccia, Ms, Cutuli, Sl, Di Gravio, V., Pennisi, Ma, Antonelli, M., Andreis, Dt, Khaliq, W., Singer, M., Hartmann, J., Harm, S., Carmona, Sa, Almudevar, Pm, Abellán, An, Ramos, Jv, Pérez, Lp, Valbuena, Bl, Sanz, Nm, Simón, If, Arrigo, M., Feliot, E., Deye, N., Cariou, A., Guidet, B., Jaber, S., Leone, M., Resche-Rigon, M., Baron, Av, Gayat, E., Frog Icu, Investigators, Balik, M., Kolnikova, I., Maly, M., Waldauf, P., Tavazzi, G., Kristof, J., Herpain, A., Su, F., Post, E., Taccone, F., Vincent, Jl, Creteur, J., Lee, C., Hatib, F., Jian, Z., Buddi, S., Cannesson, M., Fileković, S., Turel, M., Knafelj, R., Gorjup, V., Stanić, R., Gradišek, P., Cerović, O., Mirković, T., Noč, M., Tirkkonen, J., Hellevuo, H., Olkkola, Kt, Hoppu, S., Chiang, Cc, Juan, Wc, Lin, Ph, Fong, Ky, Hou, Ds, Chen, Ys, Paul, M., Bougouin, W., Geri, G., Dumas, F., Champigneulle, B., Legriel, S., Charpentier, J., Mira, Jp, Sandroni, C., Zimmerman, J., Sullivan, E., Noursadeghi, M., Fox, B., Sampson, D., Mchugh, L., Yager, T., Cermelli, S., Seldon, T., Bhide, S., Brandon, Ra, Brandon, Rb, Zwaag, J., Beunders, R., Kox, M., Gul, F., Arslantas, Mk, Genc, D., Zibandah, N., Topcu, L., Akkoc, T., Cinel, I., Greco, E., Lauretta, Mp, Garcia, Ip, Cordero, M., Martin, Ad, Pallás, Ta, Montero, Jg, Rey, Jr, Malo, Lr, Montoya, Aa, Martinez, Ad, Ayala, Ly, Zepeda, Em, Granillo, Jf, Sanchez, Ja, Alejo, Gc, Cabrera, Ar, Montenegro, Ap, Beduneau, G., Schortgen, F., Piquilloud, L., Zogheib, E., Jonas, M., Grelon, F., Runge, I., Terzi, N., Grangé, S., Barberet, G., Guitard, Pg, Frat, Jp, Constan, A., Chrétien, Jm, Mancebo, J., Mercat, A., Richard, Jc, Brochard, L., Wind, Study Group, Soilemezi, E., Koco, E., Savvidou, S., Nouris, C., Matamis, D., Plug Working Group, Di Mussi, R., Spadaro, S., Volta, Ca, Mariani, M., Colaprico, A., Antonio, C., Bruno, F., Grasso, S., Rodriguez, A., Martín-Loeches, I., Díaz, E., Masclans, Jr, Gordo, F., Solé-Violán, J., Bodí, M., Avilés-Jurado, Fx, Trefler, S., Magret, M., Reyes, Lf, Marín-Corral, J., Yebenes, Jc, Esteban, A., Anzueto, A., Aliberti, S., Restrepo, Mi, GETGAG/SEMICYUC, Larsson, Js, Redfors, B., Ricksten, Se, Haines, R., Powell-Tuck, J., Leonard, H., Ostermann, M., Berthelsen, Re, Itenov, Ts, Perner, A., Jensen, Ju, Ibsen, M., Jensen, Ae, Bestle, Mh, Bucknall, T., Dixon, J., Boa, F., Macphee, I., Philips, Bj, Aki, Research Group, St George’s University of London, Saadat, F., Samuels, T., Huddart, S., Mccormick, B., Debrunnar, R., Preece, J., Swart, M., Peden, C., Richardson, S., Forni, L., Kalfon, P., Baumstarck, K., Estagnasie, P., Geantot, Ma, Berric, A., Simon, G., Floccard, B., Signouret, T., Boucekine, M., Fromentin, M., Nyunga, M., Sossou, A., Venot, M., Robert, R., Follin, A., Renault, A., Garrouste, M., Collange, O., Levrat, Q., Villard, I., Thévenin, D., Pottecher, J., Patrigeon, Rg, Revel, N., Vigne, C., Mimoz, O., Auquier, P., Iprea, Study Group, Pawar, S., Jacques, T., Deshpande, K., Pusapati, R., Wood, B., Pulham, Ra, Wray, J., Brown, K., Pierce, C., Nadel, S., Azevedo, Jr, Montenegro, Ws, Rodrigues, Dp, Sousa, Sc, Araujo, Vf, Leitao, Al, Prazeres, Ph, Mendonca, Av, Paula, Mp, Das Neves, A., Loudet, Ci, Busico, M., Vazquez, D., Villalba, D., Lischinsky, A., Veronesi, M., Emmerich, M., Descotte, E., Juliarena, A., Bisso, Mc, Grando, M., Tapia, A., Camargo, M., Ulla, Dv, Corzo, L., Dos Santos, Hp, Ramos, A., Doglia, Ja, Estenssoro, E., Carbonara, M., Magnoni, S., Donald, Cl, Shimony, Js, Conte, V., Triulzi, F., Stretti, F., Macrì, M., Snyder, Az, Stocchetti, N., Brody, Dl, Shimanskiy, V., Savin, I., Chumaev, A., Tjepkema-Cloostermans, Mc, Hofmeijer, J., Beishuizen, A., Hom, H., Blans, Mj, Putten, Mj, Longhi, L., Frigeni, B., Curinga, M., Mingone, D., Beretta, S., Patruno, A., Gandini, L., Vargiolu, A., Ferri, F., Ceriani, R., Rottoli, MR, Lorini, L., Citerio, G., Pifferi, S., Battistini, M., Cordolcini, V., Agarossi, A., Di Rosso, R., Ortolano, F., Lourido, Cm, Cabrera, Jl, Santana, Jd, Alzola, Lm, Del Rosario, Cg, Pérez, Hr, Torrent, Rl, Eslami, S., Dalhuisen, A., Fiks, T., Hanna, Aa, Spronk, Pe, Wood, M., Maslove, D., Muscedere, J., Scott, Sh, Saha, T., Hamilton, A., Petsikas, D., Payne, D., Boyd, Jg, Mcnelly, As, Rawal, J., Connolly, B., Mcphail, Mj, Sidhu, P., Rowlerson, A., Moxham, J., Harridge, Sd, Hart, N., Montgomery, He, Jovaisa, T., Thomas, B., Gupta, D., Wijayatilake, Ds, Shum, Hp, King, Hs, Chan, Kc, Tang, Kb, Yan, Ww, Arias, Cc, Latorre, J., La Rica, As, Garrido, Em, Feijoo, Am, Gancedo, Ch, Tofiño, Al, Rodríguez, Fg, Gemmell, Lk, Campbell, R., Doherty, P., Mackay, A., Singh, N., Vitaller, S., Nagib, H., Prieto, J., Del Arco, A., Zayas, B., Gomez, C., Tirumala, S., Pasha, Sa, Kumari, Bk, Martinez-Lopez, P., Puerto-Morlán, A., Nuevo-Ortega, P., Pujol, Lm, Dolset, Ra, González, Bs, Riera, Sq, Álvarez, Jt, Quintana, S., Martínez, L., Algarte, R., Sánchez, B., Trenado, J., Brock, N., Viegas, E., Filipe, E., Cottle, D., Traynor, T., Martínez, Mv, Márquez, Mp, Gómez, Lc, Martínez, Na, Muñoz, Jm, Bellver, Bq, Varea, Mm, Llorente, Má, Calvo, Cp, Hillier, Sd, Faulds, Mc, Hendra, H., Lawrence, N., Kodate, A., Tominaga, N., Mizugaki, A., Murakami, H., Silva, S., Kerhuel, L., Malagurski, B., Chabanne, R., Laureys, S., Puybasset, L., Nobile, L., Pognuz, Er, Rossetti, Ao, Verginella, F., Gaspard, N., Ben-Hamouda, N., Oddo, M., Taccone, Fs, Iijima, H., Andersen, Lw, Raymond, T., Berg, R., Nadkarni, V., Grossestreuer, A., Kurth, T., Donnino, M., Krüger, A., Ostadal, P., Janotka, M., Vondrakova, D., Kongpolprom, N., Cholkraisuwat, J., Pekkarinen, Pt, Ristagno, G., Masson, S., Latini, R., Bendel, S., Ala-Kokko, T., Varpula, T., Vaahersalo, J., Tiainen, M., Mion, Mm, Plebani, M., Pettilä, V., Skrifvars, Mb, Finnresusci, Study Group, Son, Y., Kim, Ks, Suh, Gj, Kwon, Wy, Ko, Ji, Park, Mj, Cavicchi, Fz, Iesu, E., Tanaka, H., Otani, N., Ode, S., Ishimatsu, S., Romero, I., Martínez, F., Kruger, A., Malek, F., Neuzil, P., Yeh, Yc, Wang, Ch, Huang, Ch, Chao, A., Lee, Ct, Lai, Ch, Chan, Ws, Cheng, Yj, Sun, Wz, Kaese, S., Horstmann, C., Lebiedz, P., Mourad, M., Gaudard, P., Eliet, J., Zeroual, N., Colson, P., Mlcek, M., Hrachovina, M., Mates, M., Hala, P., Kittnar, O., Jacky, A., Rudiger, A., Spahn, Dr, Bettex, Da, Kara, A., Akin, S., Dos Reis Miranda, D., Struijs, A., Caliskan, K., Thiel, Rj, Dubois, Ea, Wilde, W., Zijlstra, F., Gommers, D., Ince, C., Marca, L., Xini, A., Mongkolpun, W., Cordeiro, Cp, Leite, Rt, Lheureux, O., Bader, A., Rincon, L., Santacruz, C., Preiser, Jc, Chao, As, Kim, W., Ahn, C., Cho, Y., Lim, Th, Oh, J., Choi, Ks, Jang, Bh, Ha, Jk, Mecklenburg, A., Stamm, J., Soeffker, G., Kubik, M., Sydow, K., Reichenspurner, H., Kluge, S., Braune, S., Bergantino, B., Ruberto, F., Magnanimi, E., Privato, E., Zullino, V., Bruno, K., Pugliese, F., Sales, G., Girotto, V., Vittone, F., Brazzi, L., Fritz, C., Kimmoun, A., Vanhuyse, F., Trifan, B., Orlowski, S., Albuisson, E., Tran, N., Levy, B., Chhor, V., Joachim, J., Chatelon, J., Fave, G., Mantz, J., Diaz, Dd, Villanova, M., Aguirregabyria, M., Andrade, G., López, L., John, G., Cowan, R., Hart, R., Lake, K., Litchfield, K., Song, Jw, Lee, Yj, Cho, Yj, Choi, S., Vermeir, P., Vandijck, D., Mariman, A., Verhaeghe, R., Deveugele, M., Vogelaers, D., Chok, L., Bachli, Eb, Bettex, D., Cottini, Sr, Keller, E., Maggiorini, M., Schuepbach, R., Stiphout, C., Grevelink, M., Vaneker, I., Ruijter, A., Buise, M., Tena, Sa, Barrachina, Lg, Portillo, Jh, Aznar, Gp, Campos, Lm, Sellés, Md, Tomás, Ma, Muncharaz, Ab, Skinner, L., Monsalvo, S., Olavarria, E., Stümpfle, R., Na, Sj, Park, J., Chung, Cr, Suh, Gy, Yang, Jh, Witter, T., Brousseau, C., Butler, Mb, Erdogan, M., Dougall, Pc, Green, Rs, Abbott, Te, Torrance, Hd, Cron, N., Vaid, N., Emmanuel, J., Siddiqui, Ss, Prabu, N., Chaudhari, Hk, Patil, Vp, Divatia, Jv, Solanki, S., Kulkarni, Ap, Gutierrez, La, Brasseur, A., Hempel, D., Stauffert, N., Recker, F., Schröder, T., Reusch, S., Schleifer, J., Breitkreutz, R., Sjövall, F., Møller, Mh, Moraes, Rb, Borges, Fk, Guillen, Ja, Zabaletta, Wj, Pics- Hcpa, Programa Intrahospitalar Combate À Sepse Do Hospital Clínicas Porto Alegre, Ruiz-Ramos, J., Marqués-Miñana, MR, Sosa, M., Concha, P., Menendez, R., Ramírez, Cs, Santana, Mc, Balcázar, Lc, Escalada, Sh, Viera, Ma, Vázquez, Cf, Díaz, Jj, Campelo, Fa, Monroy, Ns, Santana, Ps, Santana, Sr, Gutiérrez-Pizarraya, A., Garnacho-Montero, J., Martin, C., Mainardi, Jl, Cholley, B., Hubbard, A., Frontera, Pr, Vega, Lm, Miguelena, Pr, Usón, Mc, López, Ar, Clemente, Ea, Ibañes, Pg, Aguilar, Al, Palomar, M., Olaechea, P., Uriona, S., Vallverdu, M., Catalan, M., Aragon, C., Lerma, Fa, Envin-Helics, Study Group, Bassi, Gl, Xiol, Ea, Senussi, T., Idone, Fa, Motos, A., Travierso, C., Fernández-Barat, L., Amaro, R., Hua, Y., Ranzani, Ot, Bobi, Q., Rigol, M., Torres, A., Fernández, If, Soler, Ea, Vera, Ap, Pastor, Ee, Hernandis, V., Ros Martínez, J., Rubio, Rj, Torner, Mm, Brugger, Sc, Eroles, Aa, Moles, Si, Cabello, Jt, Schoenenberger, Ja, Casals, Xn, Vidal, Mv, Garrido, Bb, Martinez, Mp, Mirabella, L., Cotoia, A., Tullo, L., Stella, A., Di Bello, F., Di Gregorio, A., Dambrosio, M., Cinnella, G., Ramirez, Jr, Takahashi, H., Kazutoshi, F., Okada, Y., Oobayashi, W., Naito, T., Baidya, Dk, Maitra, S., Anand, Rk, Ray, Br, Arora, Mk, Ruffini, C., Rota, L., Corona, A., Sesana, G., Ravasi, S., Catena, E., Naumann, Dn, Mellis, C., Husheer, Sl, Bishop, J., Midwinter, Mj, Hutchings, S., Manca, T., Ramelli, A., Nicolini, F., Gherli, T., Vezzani, A., Young, A., Carmona, Af, Santiago, Ai, Guillamon, Ln, Delgado, Mj, Delgado-Amaya, M., Curiel-Balsera, E., Rivera-Romero, L., Carrero-Gómez, F., Aguayo-Dehoyos, E., Ariam, Registry Of Adult Cardiac Surgery, Healey, Aj, Cameron, C., Jiao, Lr, Pérez, A., Martin, S., Del Moral, Ol, Toval, S., Rico, J., Aldecoa, C., Oguzhan, K., Demirkiran, O., Kirman, M., Bozbay, S., Kosuk, Me, Asyralyyeva, G., Dilek, M., Duzgun, M., Telli, S., Aydin, M., Yilmazer, F., Hodgson, Le, Dimitrov, Bd, Stubbs, C., Venn, R., Vedage, D., Shawaf, S., Naran, P., Sirisena, N., Kinnear, J., Londoño, Jg, Cardenas, Cl, Ginés, As, Gubianas, Cm, Sánchez, Ec, Sirvent, Jm, Panafidina, V., Shlyk, I., Ilyina, V., Judickas, S., Kezyte, G., Urbanaviciute, I., Serpytis, M., Gaizauskas, E., Sipylaite, J., Sprung, Cl, Munteanu, G., Morales, Rc, Kasdan, H., Volker, T., Reiter, A., Cohen, Y., Himmel, Y., Meissonnier, J., Banderas-Bravo, Me, Gómez-Jiménez, C., García-Martínez, Mv, Martínez-Carmona, Jf, Fernández-Ortega, Jf, O Dwyer, Mj, Starczewska, M., Wilks, M., Rapid Diagnosis of Infections in the Critically Ill Team, Torsvik, M., Gustad, Lt, Bangstad, Il, Vinje, Lj, Damås, Jk, Solligård, E., Mehl, A., Tsunoda, M., Kang, M., Saito, M., Saito, N., Akizuki, N., Namiki, M., Takeda, M., Yuzawa, J., Yaguchi, A., Tokyo Womens Medical University, Tsirigotis, P., Chondropoulos, S., Theodorakopoulou, M., Stamouli, M., Gkirkas, K., Dimopoulou, Ik, Makiko, S., Akiduki, N., Preau, S., Ambler, M., Sigurta, A., Saeed, S., Jochmans, S., Chelly, J., Vong, Lv, Sy, O., Serbource-Goguel, J., Rolin, N., Weyer, Cm, Abdallah, Ri, Adrie, C., Vinsonneau, C., Monchi, M., Mayr, U., Huber, W., Karsten, E., Lahmer, T., Thies, P., Henschel, B., Fischer, G., Schmid, Rm, Naz, I., Yaman, G., Kou, Ps, Lozano, Ja, Sánchez, Pc, Francioni, Je, Ferrón, Fr, Simón, Jm, Riad, Z., Mezidi, M., Aublanc, M., Perinel, S., Lissonde, F., Louf-Durier, A., Yonis, H., Tapponnier, R., Louis, B., Guérin, C., Plug, Working Group, Marmanidou, K., Oikonomou, M., Loizou, C., Somhorst, P., Hayashi, K., Hirayama, T., Yumoto, T., Tsukahara, K., Iida, A., Nosaka, N., Sato, K., Ugawa, T., Nakao, A., Ujike, Y., Hirohata, S., Mojoli, F., Torriglia, F., Giannantonio, M., Orlando, A., Bianzina, S., Mongodi, S., Pozzi, M., Iotti, Ga, Braschi, A., Jansen, D., Gadgil, S., Doorduin, J., Roesthuis, L., Heunks, Lm, Chen, Gq, Sun, Xm, He, X., Yang, Yl, Shi, Zh, Xu, M., Zhou, Jx, Pereira, Sm, Tucci, MR, Tonelotto, Bf, Simoes, Cm, Morais, Cc, Pompeo, Ms, Kay, Fu, Amato, Mb, Vieira, Je, Suzuki, S., Mihara, Y., Hikasa, Y., Okahara, S., Morimatsu, H., Okayama Research Investigation Organizing Network (ORION)investigators, Kwon, Hm, Moon, Yj, Lee, Sh, Jung, Kw, Shin, Wj, Jun, Ig, Song, Jg, Hwang, Gs, Lee, S., Jung, K., Brianti, R., Fanzaghi, P., Tudor, Ba, Klaus, Da, Lebherz-Eichinger, D., Lechner, C., Schwarz, C., Bodingbauer, M., Seemann, R., Kaczirek, K., Fleischmann, E., Roth, Ga, Krenn, Cg, Malyshev, A., Sergey, S., Yoshitake, E., Kaneko, M., Tencé, N., Zaien, I., Wolf, M., Trouiller, P., Jacobs, Fm, Kelly, Jm, Veigas, P., Hollands, S., Min, A., Rizoli, S., Robles, Cm, Oca Sandoval, Ma, Tarabrin, O., Gavrychenko, D., Mazurenko, G., Tarabrin, P., Mendez, Mc, Orden, Va, Noval, Rl, Mccue, C., Gemmell, L., Luján, J., Villa, P., Llorente, B., Molina, R., Alcázar, L., Juanas, Ca, Rogero, S., Pascual, T., Cambronero, Ja, Almudévar, Pm, Domínguez, Jp, Castañeda, Dp, Lucendo, Ap, Rivas, Rf, Villamizar, Pr, Javadpour, S., Kalani, N., Amininejad, T., Jamali, S., Sobhanian, S., Laurent, A., Bonnet, M., Rigal, R., Aslanian, P., Hebert, P., Capellier, G., Ps-Icu, Group, Contreras, MR, Mejías, Cr, Ruiz, Fc, Lombardo, Md, Perez, Jc, Hoyos, Ea, Estella, A., Viciana, R., Fontaiña, Lp, Rico, T., Madueño, Vp, Recuerda, M., Fernández, L., Bonet, S., Mazo, C., Rubiera, M., Ruiz-Rodríguez, Jc, Gracia, Rm, Espinel, E., Pont, T., Kotsopoulos, A., Jansen, N., Abdo, Wf, Gopcevic, A., Gavranovic, Z., Vucic, M., Glogoski, Mz, Penavic, Lv, Horvat, A., Martin-Villen, L., Egea-Guerero, Jj, Revuelto-Rey, J., Aldabo-Pallas, T., Correa-Chamorro, E., Gallego-Corpa, Ai, Granados, Pr, Faivre, V., Wildenberg, L., Huot, B., Lukaszewicz, Ac, Simsir, M., Mengelle, C., Payen, D., La Fuente, Mv, Almudena, Pm, Muñoz, Jj, Abellan, An, Lucendo, Ma, Perez, Lp, Dominguez, Jp, Wee, S., Ong, C., Lau, Yh, Wong, Y., Olea-Jiménez, V., Mora-Ordóñez, Jm, Muñoz-Muñoz, Jl, Vallejo-Báez, J., Daga-Ruiz, D., Lebrón-Gallardo, M., Rialp, G., Raurich, Jm, Morán, I., Martín, Mc, Heras, G., Mas, A., Vallverdú, I., Hraiech, S., Bourenne, J., Guervilly, C., Forel, Jm, Adda, M., Sylla, P., Mouaci, A., Gainnier, M., Papazian, L., Bauer, Pr, Kumbamu, A., Wilson, Me, Pannu, Jk, Egginton, Js, Kashyap, R., Gajic, O., Yoshihiro, S., Sakuraya, M., Hirata, A., Kawamura, N., Tsutui, T., Yoshida, K., Hashimoto, Y., Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group, Chang, Ch, Hu, Hc, Chiu, Lc, Hung, Cy, Li, Sh, Kao, Kc, Sibley, S., Drover, J., D Arsigny, C., Parker, C., Howes, D., Moffatt, S., Erb, J., Ilan, R., Messenger, D., Ball, I., Harrison, M., Ridi, S., Andrade, Ah, Costa, Rc, Souza, Va, Gonzalez, V., Amorim, V., Rolla, F., Filho, Ca, Miranda, R., Atchasiri, S., Buranavanich, P., Wathanawatthu, T., Suwanpasu, S., Bureau, C., Rolland-Debord, C., Poitou, T., Clavel, M., Perbet, S., Kouatchet, A., Similowski, T., Demoule, A., Diaz, P., Nunes, J., Escórcio, S., Silva, G., Chaves, S., Jardim, M., Câmara, M., Fernandes, N., Duarte, R., Jardim, Jj, Pereira, Ca, Nóbrega, Jj, Chen, Cm, Lai, Cc, Cheng, Kc, Chou, W., Lee, Sj, Cha, Ys, Lee, Wy, Onodera, M., Nakataki, E., Oto, J., Imanaka, H., Nishimura, M., Khadjibaev, A., Sabirov, D., Rosstalnaya, A., Akalaev, R., Parpibaev, F., Antonucci, E., Rossini, P., Gandolfi, S., Montini, E., Orlando, S., Nes, M., Karachi, F., Hanekom, S., Pereira, Uv, Parkin, Ms, Moore, M., Carvalho, Kv, Min, Hj, Kim, Hj, Choi, Yy, Lee, Ey, Song, I., Kim, Dj, E, Yy, Kim, Jw, Park, Js, Lee, Jh, Suh, Jw, Jo, Yh, Ferrero-Calleja, J., Merino-Vega, D., González-Jiménez, Ai, Sigcha, Ms, Hernández-Tejedor, A., Martin-Vivas, A., Gabán-Díez, Á, Luna, Rr, La Calle-Pedrosa, N., Temprano-Gómez, I., Afonso-Rivero, D., Pellin-Ariño, Ji, Algora-Weber, A., Fumis, Rr, Ferraz, Ab, Junior, Jm, Kirca, H., Cakin, O., Unal, M., Mutlu, H., Ramazanoglu, A., Cengiz, M., Nicolini, Ea, Pelisson, Fg, Nunes, Rs, Da Silva, Sl, Carreira, Mm, Bellissimo-Rodrigues, F., Ferez, Ma, Basile-Filho, A., Chao, Hc, Chen, L., Hravnak, M., Clermont, G., Pinsky, M., Dubrawski, A., Varas, Jl, Montero, Rm, Sánchez-Elvira, La, Díaz, Pv, Delgado, Cp, Ruiz, Bl, Guerrero, Ap, Galache, Ja, Sherif, H., Hassanin, H., El Hossainy, R., Samy, W., Ly, H., David, H., Burtin, P., Charpentier, C., Barral, M., Courant, P., Fournel, E., Gaide-Chevronnay, L., Durand, M., Albaladejo, P., Payen, Jf, Chavanon, O., Ortiz, Ab, Pozzebon, S., Fumagalli, F., Scala, S., Affatato, R., Maglie, M., Zani, D., Novelli, D., Marra, C., Luciani, A., Luini, M., Letizia, T., Pravettoni, D., Staszewsky, L., Belloli, A., Di Giancamillo, M., Scanziani, E., Kye, Yc, Yu, Km, Babini, G., Grassi, L., Reinikainen, M., Skrifvars, M., Kappler, F., Blobner, M., Schaller, Sj, Roasio, A., Costanzo, E., Cardellino, S., Fontana, V., Park, M., You, Km, Ko, Sb, Beane, A., Thilakasiri, Mc, Silva, Ap, Stephens, T., Sigera, Cs, Athapattu, P., Jayasinghe, S., Padeniya, A., Haniffa, R., Sáez, Vc, Ruiz-Ruano, Rdel, González, As, Kunze-Szikszay, N., Wand, S., Klapsing, P., Wetz, A., Heyne, T., Schwerdtfeger, K., Troeltzsch, M., Bauer, M., Quintel, M., Moerer, O., Cook, Dj, Rutherford, Wb, Scales, Dc, Adhikari, Nk, Cuthbertson, Bh, Suzuki, T., Fushimi, K., Iwamoto, M., Nakagawa, S., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, Mw, Romero, Dg, Padilla, Ys, Kleinpell, R., Chouris, I., Radu, V., Stougianni, M., Lavrentieva, A., Lagonidis, D., Price, Rd, Day, A., Arora, N., Henderson, Ma, Hickey, S., Costa, Mi, Carvalho, Jp, Gomes, Aa, Mergulhão, Pj, Chan, Kk, Maghsoudi, B., Tabei, Sh, Sabetian, G., Tabatabaei, Hr, Akbarzadeh, A., Student Research Committee - Shiraz University of Medical Sciences, Saigal, S., Pakhare, A., Joshi, R., Pattnaik, Sk, Ray, B., Rousseau, Af, Michel, L., Bawin, M., Cavalier, E., Reginster, Jy, Damas, P., Bruyere, O., Zhou, Jc, Cauwenberghs, H., Backer, A., Neels, H., Deblier, I., Berghmans, J., Himpe, D., Barea-Mendoza, Ja, Portillo, Ip, Fernández, Mv, Gigorro, Rg, Vela, Jl, Mateos, Hm, Alves, Sc, Varas, Gm, Rodriguez-Biendicho, A., Carreño, Er, González, Jc, Yang, Js, Lin, Kl, Choi, Yj, Yoon, Sz, Gordillo-Brenes, A., Fernandez-Zamora, Md, Herruzo-Aviles, A., Garcia-Delgado, M., Hinojosa-Perez, R., ARIAM-ANDALUCIA, Pascual, Oa, Pérez, Ag, Fernández, Pa, Amor, Ll, Albaiceta, Gm, Calvo, Sa, Spazzadeschi, A., Marrazzo, F., Gandola, A., Sciurti, R., Savi, C., Tseng, Cj, Bertini, P., Sanctis, F., Guarracino, F., Baldassarri, R., Buitinck, Sh, Voort, Ph, Tsunano, Y., Izawa, M., Tane, N., Ghosh, S., Gupta, A., Gasperi, A., Mazza, E., Limuti, R., Prosperi, M., Bissenova, N., Yergaliyeva, A., Talan, L., Yılmaz, G., Güven, G., Yoruk, F., Altıntas, Nd, Mukherjee, Dn, Agarwal, Lk, Mandal, K., Balsera, B., Martinez, M., Garcia, M., Castellana, D., Lopez, R., Barcenilla, F., Kaminsky, Ge, Carreño, R., Escribá, A., Fuentes, M., Gálvez, V., Del Olmo, R., Nieto, B., Vaquerizo, C., Alvarez, J., La Torre, Ma, Torres, E., Bogossian, E., Nouer, Sa, Salgado, Dr, Jiménez, Gj, Gaite, Fb, Martínez, Mp, Doganci, M., Izdes, S., Besevli, Sg, Alkan, A., Kayaaslan, B., Penichet, Sm, López, Ma, Repessé, X., Artiguenave, M., Paktoris-Papine, S., Espinasse, F., Dinh, A., El Sayed, F., Charron, C., Géri, G., Vieillard-Baron, A., Dimitroulakis, K., Ferré, A., Guillot, M., Teboul, Jl, Lichtenstein, D., Mézière, G., Richard, C., Monnet, X., Prīdāne, S., Sabeļņikovs, O., Bianchi, I., Kondili, E., Psarologakis, C., Kokkini, S., Amargianitakis, V., Babalis, D., Chytas, A., Chouvarda, I., Vaporidi, K., Georgopoulos, D., Trapp, O., Kalenka, A., Karbing, Ds, Gioia, A., Moro, F., Corte, Fd, Mauri, T., Rees, Se, Plug working group, Petrova, Mv, Mohan, R., Butrov, Av, Beeharry, Sd, Vatsik, Mv, Sakieva, Fi, Gobert, F., Fernandez, R., Labaune, Ma, Burle, Jf, Barbier, J., Vincent, B., Cleyet, M., Shinotsuka, Cr, Törnblom, S., Nisula, S., Vaara, S., Poukkanen, M., Andersson, S., Pesonen, E., Xie, Z., Liao, X., Kang, Y., Zhang, J., Kubota, K., Egi, M., Mizobuchi, S., Hegazy, S., El-Keraie, A., El Sayed, E., El Hamid, Ma, Rodrigues, Nj, Pereira, M., Godinho, I., Gameiro, J., Neves, M., Gouveia, J., E Silva, Zc, Lopes, Ja, Mckinlay, J., Kostalas, M., Kooner, G., Dudas, G., Horton, A., Kerr, C., Karanjia, N., Creagh-Brown, B., Yamazaki, A., Ganuza, Ms, Molina, Ja, Martinez, Fh, Freile, Mt, Fernandez, Ng, Travieso, Pm, Bandert, A., Frithiof, R., Lipcsey, M., Smekal, D., Schlaepfer, P., Durovray, Jd, Plouhinec, V., Chiappa, C., Bellomo, R., Schneider, Ag, Mitchell, S., Durrant, J., Street, H., Dunthorne, E., Shears, J., Caballero, Ch, Hutchison, R., Schwarze, S., Ghabina, S., Thompson, E., Prowle, Jr, Kirwan, Cj, Gonzalez, Ca, Pinto, Jl, Orozco, V., Patiño, Ja, Garcia, Pk, Contreras, Km, Rodriguez, P., and Echeverri, Je more...

18. The servperf model as a service quality assessment tool in a company,El Modelo Servperf Como Herramienta De Evaluacion De La Calidad De Servicio En Una Empresa

Author: Ramos Farroñan, E. V., Mogollón García, F. S., Santur Manuel, L., and Cherre Morán, I.

19. Acute physiologic effects of a stepwise recruitment maneuver in acute respiratory distress syndrome

Author: Morán, I., Blanch, L., Fernández, R., Enrique Fernández Mondéjar, Zavala, E., and Mancebo, J.

20. Studies on metacercarial excystment in Himasthla leptosoma (Trematoda: Echinostomatidae) and newly emerged metacercariae

Author: Irwin, S.W.B., McKerr, G., Judge, Brenda C., and Moran, I.
Published: 1984
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21. Time course of electrical activity of the diaphragm (EAdi) in the peri extubation period and its role as predictor of extubation failure in difficult to wean patients.

Author: Parrilla-Gómez FJ, Roche-Campo F, Italiano S, Parrilla-Gómez A, Morán I, Mancebo J, and Maraffi T
Subjects: Humans, Male, Female, Prospective Studies, Middle Aged, Aged, Time Factors, Respiration, Artificial methods, Respiratory Insufficiency therapy, Respiratory Insufficiency physiopathology, Predictive Value of Tests, Ventilator Weaning methods, Diaphragm physiopathology, Airway Extubation methods, Airway Extubation statistics & numerical data
Abstract: Introduction: Weaning patients from mechanical ventilation is crucial in the management of acute respiratory failure (ARF). Spontaneous breathing trials (SBT) are used to assess readiness for extubation, but extubation failure remains a challenge. Diaphragmatic function, measured by electrical activity of the diaphragm (EAdi), may provide insights into weaning outcomes., Materials and Methods: This prospective, observational study included difficult-to-wean patients undergoing invasive mechanical ventilation. EAdi was recorded before, during, and after extubation. Patients were categorized into extubation success and failure groups based on reintubation within 48 h. Statistical analysis assessed EAdi patterns and predictive value., Results: Thirty-one patients were analyzed, with six experiencing extubation failure. Overall, EAdi increased significantly between the phases before the SBT, the SBT and post-extubation period, up to 24 h (p < 0.001). EAdi values were higher in the extubation failure group during SBT (p = 0.01). An EAdi > 30 μV during SBT predicted extubation failure with 92% sensitivity and 67% specificity. Multivariable analysis confirmed EAdi as an independent predictor of extubation failure., Conclusions: In difficult-to-wean patients, EAdi increases significantly between the phases before the SBT, the SBT and post-extubation period and is significantly higher in patients experiencing extubation failure. An EAdi > 30 μV during SBT may enhance extubation failure prediction compared to conventional parameters. Advanced monitoring of diaphragmatic function could improve weaning outcomes in critical care settings., (© 2024. The Author(s).) more...
Published: 2024
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22. Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function.

Author: Hu M, Kim I, Morán I, Peng W, Sun O, Bonnefond A, Khamis A, Bonàs-Guarch S, Froguel P, and Rutter GA
Subjects: Humans, Cell Survival genetics, Genetic Variation, Insulin metabolism, Cell Line, Zinc Transporter 8 genetics, Zinc Transporter 8 metabolism, Insulin-Secreting Cells metabolism, Enhancer Elements, Genetic, Diabetes Mellitus, Type 2 genetics, Diabetes Mellitus, Type 2 metabolism
Abstract: Variants at the SLC30A8 locus are associated with type 2 diabetes (T2D) risk. The lead variant, rs13266634, encodes an amino acid change, Arg325Trp (R325W), at the C-terminus of the secretory granule-enriched zinc transporter, ZnT8. Although this protein-coding variant was previously thought to be the sole driver of T2D risk at this locus, recent studies have provided evidence for lowered expression of SLC30A8 mRNA in protective allele carriers. In the present study, we examined multiple variants that influence SLC30A8 allele-specific expression. Epigenomic mapping has previously identified an islet-selective enhancer cluster at the SLC30A8 locus, hosting multiple T2D risk and cASE associations, which is spatially associated with the SLC30A8 promoter and additional neighboring genes. Here, we show that deletion of variant-bearing enhancer regions using CRISPR-Cas9 in human-derived EndoC-βH3 cells lowers the expression of SLC30A8 and several neighboring genes and improves glucose-stimulated insulin secretion. While downregulation of SLC30A8 had no effect on beta cell survival, loss of UTP23, RAD21, or MED30 markedly reduced cell viability. Although eQTL or cASE analyses in human islets did not support the association between these additional genes and diabetes risk, the transcriptional regulator JQ1 lowered the expression of multiple genes at the SLC30A8 locus and enhanced stimulated insulin secretion., (© 2024 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology.) more...
Published: 2024
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23. Dysregulated neutrophil extracellular traps formation in sepsis.

Author: Mulet M, Osuna-Gómez R, Zamora C, Artesero I, Arús M, Vera-Artazcoz P, Cordón A, Vilalta N, San-José P, Abril A, Moliné A, Morán I, López-Contreras J, and Vidal S
Subjects: Humans, Neutrophils metabolism, Phenotype, Extracellular Traps metabolism, Sepsis
Abstract: The migration and antimicrobial functions of neutrophils seem to be impaired during sepsis and contribute to the dysregulation of immune responses and disease pathogenesis. However, the role of neutrophil extracellular traps (NETs) remains to be clarified. The study aimed to analyse sequential phenotypic and functional changes of neutrophils during the time following the diagnosis of sepsis. We prospectively enrolled 49 septic and 18 non-septic patients from the intensive care unit (ICU) and emergency room (ER) and 20 healthy volunteers (HV). Baseline blood samples from septic and non-septic patients were collected within 12 h of admission to the hospital. Additional septic samples were drawn at 24, 48 and 72 h after baseline. Neutrophil phenotype and degranulation capacity were assessed by flow cytometry and NET formation was quantified by fluorescence. Neutrophils from septic patients exhibited increased CD66b, CD11b and CD177 expression but displayed reduced NET formation at baseline compared with non-septic patients and HV controls. Neutrophils expressing CD177 interacted less with platelets, were related to reduced NETosis and tended to indicate a worse sepsis outcome. In vitro experiments revealed that neutrophil function is compromised by the origin of sepsis, including the pathogen type and the affected organ. Assessing a decision tree model, our study showed that CD11b expression and NETosis values are useful variables to discriminate septic from non-septic patients. We conclude that sepsis induces changes in neutrophil phenotype and function that may compromise the effective capacity of the host to eliminate pathogens., (© 2023 John Wiley & Sons Ltd.) more...
Published: 2023
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24. Exhaustive Variant Interaction Analysis using Multifactor Dimensionality Reduction.

Author: Gómez-Sánchez G, Alonso L, Pérez MÁ, Morán I, Torrents D, and Berral JL
Abstract: One of the main goals of human genetics is to understand the connections between genomic variation and the predisposition to develop a complex disorder. These disease-variant associations are usually studied in a single independent manner, disregarding the possible effect derived from the interaction between genomic variants. In particular, in a background of complex diseases, these interactions can be directly linked to the disorder and may play an important role in disease development. Although their study has been suggested to help to complete the understanding of the genetic bases of complex diseases, this still represents a big challenge due to large computing demands. Here, we have taken advantage of High-Performance Computing technologies to tackle this problem using a combination of machine learning methods and statistical approaches. As a result, we have created a containerized framework that uses Multifactor Dimensionality Reduction to detect pairs of variants associated with Type 2 Diabetes (T2D). This methodology has been tested in the Northwestern University NUgene project cohort using a dataset of 1,883,192 variant pairs with a certain degree of association with T2D. Out of the pairs studied, we have identified 104 significant pairs, two of which exhibit a potential functional relationship with T2D. more...
Published: 2023
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25. Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function.

Author: Hu M, Kim I, Morán I, Peng W, Sun O, Bonnefond A, Khamis A, Bonas-Guarch S, Froguel P, and Rutter GA
Abstract: Variants at the SLC30A8 locus are associated with type 2 diabetes (T2D) risk. The lead variant, rs13266634, encodes an amino acid change, Arg325Trp (R325W), at the C-terminus of the secretory granule-enriched zinc transporter, ZnT8. Although this protein-coding variant was previously thought to be the sole driver of T2D risk at this locus, recent studies have provided evidence for lowered expression of SLC30A8 mRNA in protective allele carriers. In the present study, combined allele-specific expression (cASE) analysis in human islets revealed multiple variants that influence SLC30A8 expression. Epigenomic mapping identified an islet-selective enhancer cluster at the SLC30A8 locus, hosting multiple T2D risk and cASE associations, which is spatially associated with the SLC30A8 promoter and additional neighbouring genes. Deletions of variant-bearing enhancer regions using CRISPR-Cas9 in human-derived EndoC-βH3 cells lowered the expression of SLC30A8 and several neighbouring genes, and improved insulin secretion. Whilst down-regulation of SLC30A8 had no effect on beta cell survival, loss of UTP23 , RAD21 or MED30 markedly reduced cell viability. Although eQTL or cASE analyses in human islets did not support the association between these additional genes and diabetes risk, the transcriptional regulator JQ1 lowered the expression of multiple genes at the SLC30A8 locus and enhanced stimulated insulin secretion., Competing Interests: Conflict of Interest GAR has received grant funding from, and is a consultant for, Sun Pharmaceuticals Inc. more...
Published: 2023
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26. High-Flow Versus VenturiMask Oxygen Therapy to Prevent Reintubation in Hypoxemic Patients after Extubation: A Multicenter Randomized Clinical Trial.

Author: Maggiore SM, Jaber S, Grieco DL, Mancebo J, Zakynthinos S, Demoule A, Ricard JD, Navalesi P, Vaschetto R, Hraiech S, Klouche K, Frat JP, Lemiale V, Fanelli V, Chanques G, Natalini D, Ischaki E, Reuter D, Morán I, La Combe B, Longhini F, De Gaetano A, Ranieri VM, Brochard LJ, and Antonelli M more...
Subjects: Humans, Airway Extubation, Oxygen Inhalation Therapy adverse effects, Intubation, Intratracheal, Oxygen therapeutic use, Respiratory Insufficiency therapy, Noninvasive Ventilation
Abstract: Rationale: When compared with VenturiMask after extubation, high-flow nasal oxygen provides physiological advantages. Objectives: To establish whether high-flow oxygen prevents endotracheal reintubation in hypoxemic patients after extubation, compared with VenturiMask. Methods: In this multicenter randomized trial, 494 patients exhibiting Pa O 2 :Fi O 2 ratio ⩽ 300 mm Hg after extubation were randomly assigned to receive high-flow or VenturiMask oxygen, with the possibility to apply rescue noninvasive ventilation before reintubation. High-flow use in the VenturiMask group was not permitted. Measurements and Main Results: The primary outcome was the rate of reintubation within 72 hours according to predefined criteria, which were validated a posteriori by an independent adjudication committee. Main secondary outcomes included reintubation rate at 28 days and the need for rescue noninvasive ventilation according to predefined criteria. After intubation criteria validation ( n = 492 patients), 32 patients (13%) in the high-flow group and 27 patients (11%) in the VenturiMask group required reintubation at 72 hours (unadjusted odds ratio, 1.26 [95% confidence interval (CI), 0.70-2.26]; P = 0.49). At 28 days, the rate of reintubation was 21% in the high-flow group and 23% in the VenturiMask group (adjusted hazard ratio, 0.89 [95% CI, 0.60-1.31]; P = 0.55). The need for rescue noninvasive ventilation was significantly lower in the high-flow group than in the VenturiMask group: at 72 hours, 8% versus 17% (adjusted hazard ratio, 0.39 [95% CI, 0.22-0.71]; P = 0.002) and at 28 days, 12% versus 21% (adjusted hazard ratio, 0.52 [95% CI, 0.32-0.83]; P = 0.007). Conclusions: Reintubation rate did not significantly differ between patients treated with VenturiMask or high-flow oxygen after extubation. High-flow oxygen yielded less frequent use of rescue noninvasive ventilation. Clinical trial registered with www.clinicaltrials.gov (NCT02107183). more...
Published: 2022
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27. Drug-drug interactions in an intensive care unit and comparison of updates in two databases.

Author: Riera P, Sole N, Suárez JC, López PA, Fonts N, Rodríguez-Farre N, Fernández de Gamarra-Martínez E, and Morán I
Subjects: Databases, Factual, Drug Interactions, Humans, Hypnotics and Sedatives, Critical Care, Intensive Care Units
Abstract: Objective: Critically ill patients are at increased risk of drug-drug interactions but their prevalence and clinical relevance remains unclear. The prevalence of potential drug-drug interactions in an intensive care unit according to Micromedex Drug-Reax® and Lexi-Interact® databases was studied and the concordance between the two databases was assessed. In addition, drug-drug interactions detected in 2013 were compared with those identified in 2018 to determine updates between these years., Method: Between January and June 2013, 152 critical care patients were prospectively included. Cardiac patients were excluded. Demographic and clinical data together with the drugs administered on the first calendar day of intensive care unit admission were recorded. Potential drug-drug interactions were searched in both Drug-Reax® and Lexi-Interact ® and their prevalence, level of severity and evidence were compared considering the same sample in 2013 and 2018., Results: In 2013, 1,025 potential drug-drug interactions were identified, corresponding to 438 unique pairs. Lexi-Interact® identified more interactions (92.8%) than Drug-Reax® (34.0%). The percentage of agreement between databases was 27.4%. The number of interactions included in both databases increased after the five years but their level of evidence decreased. The most common potential drug-drug interactions involved sedatives and analgesics, intentionally prescribed concomitantly. Only two potential drug-drug interactions were classified as contraindicated by both databases. None of the potential drug-drug interactions identified had a noticeable clinical impact. Neither did they imply a prescription change., Conclusions: This study shows that the prevalence of potential drugdrug interactions in the intensive care unit is high, although their clinical relevance is generally low. Our data also show a lack of concordance between Drug-Reax® and Lexi-Interact®, as well as their updates., (Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.) more...
Published: 2022

28. Formant-Based Recognition of Words and Other Naturalistic Sounds in Rhesus Monkeys.

Author: Melchor J, Vergara J, Figueroa T, Morán I, and Lemus L
Abstract: In social animals, identifying sounds is critical for communication. In humans, the acoustic parameters involved in speech recognition, such as the formant frequencies derived from the resonance of the supralaryngeal vocal tract, have been well documented. However, how formants contribute to recognizing learned sounds in non-human primates remains unclear. To determine this, we trained two rhesus monkeys to discriminate target and non-target sounds presented in sequences of 1-3 sounds. After training, we performed three experiments: (1) We tested the monkeys' accuracy and reaction times during the discrimination of various acoustic categories; (2) their ability to discriminate morphing sounds; and (3) their ability to identify sounds consisting of formant 1 (F1), formant 2 (F2), or F1 and F2 (F1F2) pass filters. Our results indicate that macaques can learn diverse sounds and discriminate from morphs and formants F1 and F2, suggesting that information from few acoustic parameters suffice for recognizing complex sounds. We anticipate that future neurophysiological experiments in this paradigm may help elucidate how formants contribute to the recognition of sounds., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Melchor, Vergara, Figueroa, Morán and Lemus.) more...
Published: 2021
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29. TIGER: The gene expression regulatory variation landscape of human pancreatic islets.

Author: Alonso L, Piron A, Morán I, Guindo-Martínez M, Bonàs-Guarch S, Atla G, Miguel-Escalada I, Royo R, Puiggròs M, Garcia-Hurtado X, Suleiman M, Marselli L, Esguerra JLS, Turatsinze JV, Torres JM, Nylander V, Chen J, Eliasson L, Defrance M, Amela R, Mulder H, Gloyn AL, Groop L, Marchetti P, Eizirik DL, Ferrer J, Mercader JM, Cnop M, and Torrents D more...
Subjects: Humans, Cyclin D2 genetics, Cyclin D2 metabolism, Databases, Genetic, Epigenome, Europe, Gene Frequency, Genetic Predisposition to Disease, Genome-Wide Association Study, Phenotype, Quantitative Trait Loci, Transcriptome, Zinc Transporter 8 genetics, Zinc Transporter 8 metabolism, Diabetes Mellitus, Type 2 genetics, Diabetes Mellitus, Type 2 metabolism, Genetic Variation, Genomics, Islets of Langerhans metabolism
Abstract: Genome-wide association studies (GWASs) identified hundreds of signals associated with type 2 diabetes (T2D). To gain insight into their underlying molecular mechanisms, we have created the translational human pancreatic islet genotype tissue-expression resource (TIGER), aggregating >500 human islet genomic datasets from five cohorts in the Horizon 2020 consortium T2DSystems. We impute genotypes using four reference panels and meta-analyze cohorts to improve the coverage of expression quantitative trait loci (eQTL) and develop a method to combine allele-specific expression across samples (cASE). We identify >1 million islet eQTLs, 53 of which colocalize with T2D signals. Among them, a low-frequency allele that reduces T2D risk by half increases CCND2 expression. We identify eight cASE colocalizations, among which we found a T2D-associated SLC30A8 variant. We make all data available through the TIGER portal (http://tiger.bsc.es), which represents a comprehensive human islet genomic data resource to elucidate how genetic variation affects islet function and translates into therapeutic insight and precision medicine for T2D., Competing Interests: Declaration of interests A.L.G.’s spouse is an employee of Genentech and holds stock options in Roche., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.) more...
Published: 2021
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30. Preconditioning-Activated AKT Controls Neuronal Tolerance to Ischemia through the MDM2-p53 Pathway.

Author: Barrio E, Vecino R, Sánchez-Morán I, Rodríguez C, Suárez-Pindado A, Bolaños JP, Almeida A, and Delgado-Esteban M
Subjects: Animals, Apoptosis physiology, HEK293 Cells, Humans, Ischemic Preconditioning methods, Mice, Mice, Inbred C57BL, Neuroprotection physiology, Phosphatidylinositol 3-Kinases metabolism, Phosphorylation physiology, Wortmannin metabolism, Ischemia metabolism, Neurons metabolism, Proto-Oncogene Proteins c-akt metabolism, Proto-Oncogene Proteins c-mdm2 metabolism, Signal Transduction physiology, Tumor Suppressor Protein p53 metabolism
Abstract: One of the most important mechanisms of preconditioning-mediated neuroprotection is the attenuation of cell apoptosis, inducing brain tolerance after a subsequent injurious ischemia. In this context, the antiapoptotic PI3K/AKT signaling pathway plays a key role by regulating cell differentiation and survival. Active AKT is known to increase the expression of murine double minute-2 (MDM2), an E3-ubiquitin ligase that destabilizes p53 to promote the survival of cancer cells. In neurons, we recently showed that the MDM2-p53 interaction is potentiated by pharmacological preconditioning, based on subtoxic stimulation of NMDA glutamate receptor, which prevents ischemia-induced neuronal apoptosis. However, whether this mechanism contributes to the neuronal tolerance during ischemic preconditioning (IPC) is unknown. Here, we show that IPC induced PI3K-mediated phosphorylation of AKT at Ser 473 , which in turn phosphorylated MDM2 at Ser 166 . This phosphorylation triggered the nuclear stabilization of MDM2, leading to p53 destabilization, thus preventing neuronal apoptosis upon an ischemic insult. Inhibition of the PI3K/AKT pathway with wortmannin or by AKT silencing induced the accumulation of cytosolic MDM2, abrogating IPC-induced neuroprotection. Thus, IPC enhances the activation of PI3K/AKT signaling pathway and promotes neuronal tolerance by controlling the MDM2-p53 interaction. Our findings provide a new mechanistic pathway involved in IPC-induced neuroprotection via modulation of AKT signaling, suggesting that AKT is a potential therapeutic target against ischemic injury. more...
Published: 2021
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31. Auditory decisions in the supplementary motor area.

Author: Morán I, Perez-Orive J, Melchor J, Figueroa T, and Lemus L
Subjects: Animals, Learning, Macaca mulatta, Movement, Neurons, Motor Cortex
Abstract: In human speech and communication across various species, recognizing and categorizing sounds is fundamental for the selection of appropriate behaviors. However, how does the brain decide which action to perform based on sounds? We explored whether the supplementary motor area (SMA), responsible for linking sensory information to motor programs, also accounts for auditory-driven decision making. To this end, we trained two rhesus monkeys to discriminate between numerous naturalistic sounds and words learned as target (T) or non-target (nT) categories. We found that the SMA at single and population neuronal levels perform decision-related computations that transition from auditory to movement representations in this task. Moreover, we demonstrated that the neural population is organized orthogonally during the auditory and the movement periods, implying that the SMA performs different computations. In conclusion, our results suggest that the SMA integrates acoustic information in order to form categorical signals that drive behavior., (Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.) more...
Published: 2021
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32. Mitochondrial-nuclear p53 trafficking controls neuronal susceptibility in stroke.

Author: Almeida A, Sánchez-Morán I, and Rodríguez C
Subjects: Animals, Brain Ischemia metabolism, Brain Ischemia pathology, Cell Death, Humans, Polymorphism, Single Nucleotide, Prognosis, Protein Transport, Stroke metabolism, Tumor Suppressor Protein p53 genetics, Mitochondria metabolism, Neurons metabolism, Stroke pathology, Tumor Suppressor Protein p53 metabolism
Abstract: Stroke is a major cause of death and long-term disability in the adult. Neuronal apoptosis plays an essential role in the pathophysiology of ischemic brain damage and impaired functional recovery after stroke. The tumor suppressor protein p53 regulates key cellular processes, including cell cycle arrest, DNA repair, senescence, and apoptosis. Under cellular stress conditions, p53 undergoes post-translational modifications, which control protein localization, stability, and proapoptotic activity. After stroke, p53 rapidly accumulates in the ischemic brain, where it activates neuronal apoptosis through both transcriptional-dependent and -independent programs. Over the last years, subcellular localization of p53 has emerged as an important regulator of ischemia-induced neuronal apoptosis. Upon an ischemic insult, p53 rapidly translocates to the mitochondria and interacts with B-cell lymphoma-2 family proteins, which activate the mitochondrial apoptotic program, with higher efficacy than through its activity as a transcription factor. Moreover, the identification of a human single nucleotide polymorphism at codon 72 of the Tp53 gene that controls p53 mitochondrial localization and cell susceptibility to apoptosis supports the important role of the p53 mitochondrial program in neuronal survival and functional recovery after stroke. In this article, we review the relevance of mitochondrial and nuclear localization of p53 on neuronal susceptibility to cerebral ischemia and its impact on functional outcome of stroke patients., (© 2021 The Authors. IUBMB Life published by Wiley Periodicals LLC on behalf of International Union of Biochemistry and Molecular Biology.) more...
Published: 2021
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33. Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke.

Author: Sánchez-Morán I, Rodríguez C, Lapresa R, Agulla J, Sobrino T, Castillo J, Bolaños JP, and Almeida A
Subjects: Animals, Cell Survival genetics, DNA Repair, Glucose metabolism, Humans, Mice, Neurons metabolism, Transcription Factors metabolism, Cell Nucleus metabolism, Molecular Chaperones metabolism, Stroke genetics, Stroke metabolism, Telomerase metabolism
Abstract: Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that regulates DNA repair in this neurological disorder is unknown. Here, we found that DSBs in oxygen/glucose-deprived (OGD) neurons spatiotemporally correlated with the up-regulation of WRAP53 (WD40-encoding p53-antisense RNA), which translocated to the nucleus to activate the DSB repair response. Mechanistically, OGD triggered a burst in reactive oxygen species that induced both DSBs and translocation of WRAP53 to the nucleus to promote DNA repair, a pathway that was confirmed in an in vivo mouse model of stroke. Noticeably, nuclear translocation of WRAP53 occurred faster in OGD neurons expressing the Wrap53 human nonsynonymous single-nucleotide polymorphism (SNP) rs2287499 (c.202C>G). Patients carrying this SNP showed less infarct volume and better functional outcome after stroke. These results indicate that WRAP53 fosters DNA repair and neuronal survival to promote functional recovery after stroke., (Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).) more...
Published: 2020
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34. Influence of alexithymia on the management of Latin American patients with asthma: A cross-sectional study.

Author: Vanegas E, Felix M, Ramon GD, López Jove O, Matos Benavides EE, Tinoco-Morán I, Bernstein JA, and Cherrez-Ojeda I
Abstract: Objectives: In asthmatic patients, studies suggest that alexithymia leads to negative consequences and emotions that can affect physical, psychological, and social aspects of life. We designed this study to determine the frequency of alexithymia in Latin American patients with asthma, as well as to understand how this personality trait and each of its components interact with asthma severity and demographic variables, and their implications on treatment adherence and disease control under such setting., Methods: We conducted a cross-sectional study, involving 265 Latin American patients with asthma. Patient demographics and clinical characteristics were reported. The presence of alexithymia, asthma severity, and control, as well as treatment adherence, was analyzed. To assess the presence of alexithymia, the 20-item Toronto Alexithymia Scale was used. For the statistical analyses, we performed Kendall's tau-b correlation coefficient, chi-square tests for association, and one-way analysis of variance., Results: A total of 265 patients participated in the study with a gender distribution of 69.4% female and an average age of 54.7 years. In total, 30.2% of individuals presented alexithymia. There was a statistically significant correlation between educational level and 20-item Toronto Alexithymia Scale categories ( p < .001), as well as a higher proportion of severe (35.1%, p = .001) and uncontrolled (50.0%, p = .185) asthma in patients with alexithymia. A higher proportion of patients with some level of non-adherence was seen on those with uncontrolled asthma (68.5%, p = .008)., Conclusion: Our results suggest that in our sample, 3 in 10 Latin American asthma patients have alexithymia, and such mental condition is more common in those individuals with lower educational levels. Individuals with alexithymia present with severe asthma more frequently than do patients with possible or no alexithymia and are also more likely to have their disease uncontrolled., Competing Interests: Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2020.) more...
Published: 2020
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35. Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases.

Author: González JR, Ruiz-Arenas C, Cáceres A, Morán I, López-Sánchez M, Alonso L, Tolosana I, Guindo-Martínez M, Mercader JM, Esko T, Torrents D, González J, and Pérez-Jurado LA
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Alleles, Chromosomes, Human, Pair 16 genetics, Chromosomes, Human, Pair 8 genetics, Datasets as Topic standards, Diabetes Mellitus pathology, Europe ethnology, Female, Gene Expression Profiling, Haplotypes, Humans, Hypertension complications, Islets of Langerhans metabolism, Islets of Langerhans pathology, Male, Middle Aged, Polymorphism, Single Nucleotide genetics, Reproducibility of Results, Young Adult, Chromosome Inversion genetics, Diabetes Mellitus genetics, Genetic Predisposition to Disease, Hypertension genetics, Obesity complications, Obesity genetics, Polymorphism, Genetic
Abstract: The burden of several common diseases including obesity, diabetes, hypertension, asthma, and depression is increasing in most world populations. However, the mechanisms underlying the numerous epidemiological and genetic correlations among these disorders remain largely unknown. We investigated whether common polymorphic inversions underlie the shared genetic influence of these disorders. We performed an inversion association analysis including 21 inversions and 25 obesity-related traits on a total of 408,898 Europeans and validated the results in 67,299 independent individuals. Seven inversions were associated with multiple diseases while inversions at 8p23.1, 16p11.2, and 11q13.2 were strongly associated with the co-occurrence of obesity with other common diseases. Transcriptome analysis across numerous tissues revealed strong candidate genes for obesity-related traits. Analyses in human pancreatic islets indicated the potential mechanism of inversions in the susceptibility of diabetes by disrupting the cis-regulatory effect of SNPs from their target genes. Our data underscore the role of inversions as major genetic contributors to the joint susceptibility to common complex diseases., (Copyright © 2020 American Society of Human Genetics. All rights reserved.) more...
Published: 2020
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36. Medication errors in prescription and administration in critically ill patients.

Author: Suclupe S, Martinez-Zapata MJ, Mancebo J, Font-Vaquer A, Castillo-Masa AM, Viñolas I, Morán I, and Robleda G
Subjects: Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Young Adult, Critical Illness therapy, Inappropriate Prescribing statistics & numerical data, Medication Errors nursing, Medication Errors statistics & numerical data, Prescription Drugs administration & dosage
Abstract: Aim: To determine the prevalence and magnitude of medication errors and their association with patients' sociodemographic and clinical characteristics and nurses' work conditions., Design: An observational, analytical, cross-sectional and ambispective study was conducted in critically ill adult patients., Methods: Data concerning prescription errors were collected retrospectively from medical records and administration errors were identified through direct observation of nurses during drug administration. Those data were collected between April and July 2015., Results: A total of 650 prescription errors were identified for 961 drugs in 90 patients (mean error 7[SD 4.1] per patient) and prevalence of 47.1% (95% CI 44-50). The most frequent error was omission of the prescribed medication. Intensive care unit stay was a risk factor associated with omission error (OR 2.14; 1.46-3.14: p < .01). A total of 294 administration errors were identified for 249 drugs in 52 patients (mean error 6 [SD 6.7] per patient) and prevalence of 73.5% (95% CI 68-79). The most frequent error was interruption during drug administration. Admission to the intensive care unit (OR 0.37; 0.21-0.66: p < .01), nurses' morning shift (OR 2.15; 1.10-4.18: p = .02) and workload perception (OR 3.64; 2.09-6.35: p < .01) were risk factors associated with interruption., Conclusions: Medication errors in prescription and administration were frequent. Timely detection of errors and promotion of a medication safety culture are necessary to reduce them and ensure the quality of care in critically ill patients., Impact: Medication errors occur frequently in the intensive care unit but are not always identified. Due to the vulnerability of seriously ill patients and the specialized care they require, an error can result in serious adverse events. The study shows that medication errors in prescription and administration are recurrent but preventable. These findings contribute to promote awareness in the proper use of medications and guarantee the quality of nursing care., (© 2020 John Wiley & Sons Ltd.) more...
Published: 2020
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37. A novel human Cdh1 mutation impairs anaphase promoting complex/cyclosome activity resulting in microcephaly, psychomotor retardation, and epilepsy.

Author: Rodríguez C, Sánchez-Morán I, Álvarez S, Tirado P, Fernández-Mayoralas DM, Calleja-Pérez B, Almeida Á, and Fernández-Jaén A
Subjects: Child, Preschool, Humans, Male, Mutation, Missense, Anaphase-Promoting Complex-Cyclosome genetics, Antigens, CD genetics, Cadherins genetics, Epilepsy genetics, Microcephaly genetics, Psychomotor Disorders genetics
Abstract: The Fizzy-related protein 1 (Fzr1) gene encodes Cdh1 protein, a coactivator of the E3 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C). Previously, we found that genetic ablation of Fzr1 promotes the death of neural progenitor cells leading to neurogenesis impairment and microcephaly in mouse. To ascertain the possible translation of these findings in humans, we searched for mutations in the Fzr1 gene in 390 whole exomes sequenced in trio in individuals showing neurodevelopmental disorders compatible with a genetic origin. We found a novel missense (p.Asp187Gly) Fzr1 gene mutation (c.560A>G) in a heterozygous state in a 4-year-old boy, born from non-consanguineous Spanish parents, who presents with severe antenatal microcephaly, psychomotor retardation, and refractory epilepsy. Cdh1 protein levels in leucocytes isolated from the patient were significantly lower than those found in his parents. Expression of the Asp187Gly mutant form of Cdh1 in human embryonic kidney 293T cells produced less Cdh1 protein and APC/C activity, resulting in altered cell cycle distribution when compared with cells expressing wild-type Cdh1. Furthermore, ectopic expression of the Asp187Gly mutant form of Cdh1 in cortical progenitor cells in primary culture failed to abolish the enlargement of the replicative phase caused by knockout of endogenous Cdh1. These results indicate that the loss of function of APC/C-Cdh1 caused by Cdh1 Asp187Gly mutation is a new cause of prenatal microcephaly, psychomotor retardation, and severe epilepsy. Read the Editorial Highlight for this article on page 8. Cover Image for this issue: doi: 10.1111/jnc.14524., (© 2019 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of International Society for Neurochemistry.) more...
Published: 2019
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38. Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.

Author: Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos-Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, and Ferrer J more...
Subjects: Chromatin genetics, Cohort Studies, Diabetes Mellitus, Type 2 metabolism, Diabetes Mellitus, Type 2 pathology, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Molecular Conformation, Promoter Regions, Genetic, Chromatin chemistry, Diabetes Mellitus, Type 2 genetics, Enhancer Elements, Genetic, Gene Expression Regulation, Gene Regulatory Networks, Insulin Secretion genetics, Islets of Langerhans metabolism
Abstract: Genetic studies promise to provide insight into the molecular mechanisms underlying type 2 diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer clusters or super-enhancers. So far, such domains have been defined through clustering of enhancers in linear genome maps rather than in three-dimensional (3D) space. Furthermore, their target genes are often unknown. We have created promoter capture Hi-C maps in human pancreatic islets. This linked diabetes-associated enhancers to their target genes, often located hundreds of kilobases away. It also revealed >1,300 groups of islet enhancers, super-enhancers and active promoters that form 3D hubs, some of which show coordinated glucose-dependent activity. We demonstrate that genetic variation in hubs impacts insulin secretion heritability, and show that hub annotations can be used for polygenic scores that predict T2D risk driven by islet regulatory variants. Human islet 3D chromatin architecture, therefore, provides a framework for interpretation of T2D genome-wide association study (GWAS) signals. more...
Published: 2019
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39. Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization.

Author: Lapresa R, Agulla J, Sánchez-Morán I, Zamarreño R, Prieto E, Bolaños JP, and Almeida A
Subjects: Alzheimer Disease metabolism, Alzheimer Disease pathology, Amyloid beta-Peptides metabolism, Animals, Apoptosis, Dendrites drug effects, Dendrites pathology, Infusions, Intraventricular, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria drug effects, Mitochondria pathology, Neurons drug effects, Neurons metabolism, Neurons pathology, Peptide Fragments metabolism, Phosphorylation, Signal Transduction, Tumor Suppressor Protein p53 antagonists & inhibitors, Tumor Suppressor Protein p53 genetics, Amyloid beta-Peptides toxicity, Cyclin-Dependent Kinase 5 metabolism, Peptide Fragments toxicity, Tumor Suppressor Protein p53 metabolism
Abstract: Neurodegeneration in selective brain areas underlies the pathology of Alzheimer's disease (AD). Although oligomeric amyloid-β (Aβ) plays a central role in the AD pathogenesis, the mechanism of neuronal loss in response to Aβ remains elusive. The p53 tumor suppressor protein, a key regulator of cell apoptosis, has been described to accumulate in affected brain areas from AD patients. However, whether p53 plays any role in AD pathogenesis remains unknown. To address this issue, here we investigated the involvement of p53 on Aß-induced neuronal apoptosis. We found that exposure of neurons to oligomers of the amyloidogenic fragment 25-35 of the Aß peptide (Aβ 25-35 ) promoted p53 protein phosphorylation and stabilization, leading to mitochondrial dysfunction and neuronal apoptosis. To address the underlying mechanism, we focused on cyclin dependent kinase-5 (Cdk5), a known p53-phosphorylating kinase. The results revealed that Aβ 25-35 treatment activated Cdk5, and that inhibiting Cdk5 activity prevented p53 protein stabilization. Furthermore, Aβ 25-35 -mediated mitochondrial dysfunction and neuronal apoptosis were prevented by both genetic and pharmacological inhibition of either p53 or Cdk5 activities. This effect was mimicked with the full-length peptide Aβ 1-42 . To confirm the mechanism in vivo, Aβ 25-35 was stereotaxically injected in the cerebral right ventricle of mice, a treatment that caused p53 protein accumulation, dendrite disruption and neuronal death. Furthermore, these effects were prevented in p53 knockout mice or by pharmacologically inhibiting p53. Thus, Aβ 25-35 triggers Cdk5 activation to induce p53 phosphorylation and stabilization, which leads to neuronal damage. Inhibition of the Cdk5-p53 pathway may therefore represent a novel therapeutic strategy against Aβ-induced neurodegeneration., (Copyright © 2018 Elsevier Ltd. All rights reserved.) more...
Published: 2019
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40. Single-Nucleotide Polymorphism 309T>G in the MDM2 Promoter Determines Functional Outcome After Stroke.

Author: Rodríguez C, Ramos-Araque ME, Domínguez-Martínez M, Sobrino T, Sánchez-Morán I, Agulla J, Delgado-Esteban M, Gómez-Sánchez JC, Bolaños JP, Castillo J, and Almeida A
Subjects: Alleles, Animals, Genotype, Humans, Mice, Inbred C57BL, Risk Factors, Stroke therapy, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide genetics, Proto-Oncogene Proteins c-mdm2 genetics, Recovery of Function genetics, Stroke genetics
Abstract: Background and Purpose- The E3 ubiquitin ligase MDM2 (murine double minute 2) is the main negative regulator of the p53 protein-a key player in neuronal apoptosis after ischemia. A functional single-nucleotide polymorphism in the human MDM2 gene promoter (rs2279744) regulates MDM2 protein expression. We investigated whether the MDM2 SNP309, by controlling p53-mediated apoptosis, determines functional outcome after stroke. Methods- Primary cortical neurons were subjected to oxygen and glucose deprivation. Mice were subjected to ischemic (transient middle cerebral artery occlusion) or hemorrhagic (collagenase injection) stroke models. Protein and mRNA levels of MDM2 and p53 were measured in both neuronal and brain extracts. The interaction of MDM2 with p53 was disrupted by neuronal treatment with nutlin-3a. siRNA was used to knockdown MDM2 expression. We analyzed the link between the MDM2 SNP309 and functional outcome, measured by the modified Rankin Scale scores, in 2 independent hospital-based stroke cohorts: ischemic stroke cohort (408 patients) and intracerebral hemorrhage cohort (128 patients). Results- Experimental stroke and oxygen and glucose deprivation induced the expression of MDM2 in the brain and neurons, respectively. Moreover, oxygen and glucose deprivation promoted MDM2 binding with p53 in neurons. Disruption of the MDM2-p53 interaction with nutlin-3a, or MDM2 knockdown by siRNA, triggered p53 accumulation, which increased neuronal susceptibility to oxygen and glucose deprivation-induced apoptosis. Finally, we showed that patients harboring the G allele in the MDM2 promoter had higher MDM2 protein levels and showed better functional outcome after stroke than those harboring the T/T genotype. The T/T genotype was also associated with large infarct volume in ischemic stroke and increased lesion volume in patients with intracerebral hemorrhage. Conclusions- Our results reveal a novel role for the MDM2-p53 interaction in neuronal apoptosis after ischemia and show that the MDM2 SNP309 determines the functional outcome of patients after stroke. more...
Published: 2018
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41. [Metabolic syndrome and chronic urticaria].

Author: Chérrez-Ojeda I, Simancas-Racines D, Greiding L, and Tinoco-Morán I
Subjects: Chronic Disease, Humans, Mexico, Quality of Life, Chronic Urticaria, Metabolic Syndrome, Urticaria
Published: 2018
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42. Lung volumes and lung volume recruitment in ARDS: a comparison between supine and prone position.

Author: Aguirre-Bermeo H, Turella M, Bitondo M, Grandjean J, Italiano S, Festa O, Morán I, and Mancebo J
Abstract: Background: The use of positive end-expiratory pressure (PEEP) and prone position (PP) is common in the management of severe acute respiratory distress syndrome patients (ARDS). We conducted this study to analyze the variation in lung volumes and PEEP-induced lung volume recruitment with the change from supine position (SP) to PP in ARDS patients., Methods: The investigation was conducted in a multidisciplinary intensive care unit. Patients who met the clinical criteria of the Berlin definition for ARDS were included. The responsible physician set basal PEEP. To avoid hypoxemia, FiO 2 was increased to 0.8 1 h before starting the protocol. End-expiratory lung volume (EELV) and functional residual capacity (FRC) were measured using the nitrogen washout/washin technique. After the procedures in SP, the patients were turned to PP and 1 h later the same procedures were made in PP., Results: Twenty-three patients were included in the study, and twenty were analyzed. The change from SP to PP significantly increased FRC (from 965 ± 397 to 1140 ± 490 ml, p = 0.008) and EELV (from 1566 ± 476 to 1832 ± 719 ml, p = 0.008), but PEEP-induced lung volume recruitment did not significantly change (269 ± 186 ml in SP to 324 ± 188 ml in PP, p = 0.263). Dynamic strain at PEEP decreased with the change from SP to PP (0.38 ± 0.14 to 0.33 ± 0.13, p = 0.040)., Conclusions: As compared to supine, prone position increases resting lung volumes and decreases dynamic lung strain. more...
Published: 2018
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43. APC/C Cdh1 -Rock2 pathway controls dendritic integrity and memory.

Author: Bobo-Jiménez V, Delgado-Esteban M, Angibaud J, Sánchez-Morán I, de la Fuente A, Yajeya J, Nägerl UV, Castillo J, Bolaños JP, and Almeida A
Subjects: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine analogs & derivatives, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine pharmacology, Anaphase-Promoting Complex-Cyclosome genetics, Animals, Cdh1 Proteins genetics, Cell Survival, Memory drug effects, Memory physiology, Mice, Mice, Knockout, Neurons physiology, Protein Kinase Inhibitors pharmacology, Signal Transduction, rho-Associated Kinases genetics, Anaphase-Promoting Complex-Cyclosome metabolism, Cdh1 Proteins metabolism, Dendritic Cells physiology, Gene Expression Regulation physiology, rho-Associated Kinases metabolism
Abstract: Disruption of neuronal morphology contributes to the pathology of neurodegenerative disorders such as Alzheimer's disease (AD). However, the underlying molecular mechanisms are unknown. Here, we show that postnatal deletion of Cdh1, a cofactor of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase in neurons [Cdh1 conditional knockout (cKO)], disrupts dendrite arborization and causes dendritic spine and synapse loss in the cortex and hippocampus, concomitant with memory impairment and neurodegeneration, in adult mice. We found that the dendrite destabilizer Rho protein kinase 2 (Rock2), which accumulates in the brain of AD patients, is an APC/C Cdh1 substrate in vivo and that Rock2 protein and activity increased in the cortex and hippocampus of Cdh1 cKO mice. In these animals, inhibition of Rock activity, using the clinically approved drug fasudil, prevented dendritic network disorganization, memory loss, and neurodegeneration. Thus, APC/C Cdh1 -mediated degradation of Rock2 maintains the dendritic network, memory formation, and neuronal survival, suggesting that pharmacological inhibition of aberrantly accumulated Rock2 may be a suitable therapeutic strategy against neurodegeneration., Competing Interests: The authors declare no conflict of interest. more...
Published: 2017
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44. End-inspiratory pause prolongation in acute respiratory distress syndrome patients: effects on gas exchange and mechanics.

Author: Aguirre-Bermeo H, Morán I, Bottiroli M, Italiano S, Parrilla FJ, Plazolles E, Roche-Campo F, and Mancebo J
Abstract: Background: End-inspiratory pause (EIP) prolongation decreases dead space-to-tidal volume ratio (Vd/Vt) and PaCO2. We do not know the physiological benefits of this approach to improve respiratory system mechanics in acute respiratory distress syndrome (ARDS) patients when mild hypercapnia is of no concern., Methods: The investigation was conducted in an intensive care unit of a university hospital, and 13 ARDS patients were included. The study was designed in three phases. First phase, baseline measurements were taken. Second phase, the EIP was prolonged until one of the following was achieved: (1) EIP of 0.7 s; (2) intrinsic positive end-expiratory pressure ≥1 cmH2O; or (3) inspiratory-expiratory ratio 1:1. Third phase, the Vt was decreased (30 mL every 30 min) until PaCO2 equal to baseline was reached. FiO2, PEEP, airflow and respiratory rate were kept constant., Results: EIP was prolonged from 0.12 ± 0.04 to 0.7 s in all patients. This decreased the Vd/Vt and PaCO2 (0.70 ± 0.07 to 0.64 ± 0.08, p < 0.001 and 54 ± 9 to 50 ± 8 mmHg, p = 0.001, respectively). In the third phase, the decrease in Vt (from 6.3 ± 0.8 to 5.6 ± 0.8 mL/Kg PBW, p < 0.001) allowed to decrease plateau pressure and driving pressure (24 ± 3 to 22 ± 3 cmH2O, p < 0.001 and 13.4 ± 3.6 to 10.9 ± 3.1 cmH2O, p < 0.001, respectively) and increased respiratory system compliance from 29 ± 9 to 32 ± 11 mL/cmH2O (p = 0.001). PaO2 did not significantly change., Conclusions: Prolonging EIP allowed a significant decrease in Vt without changes in PaCO2 in passively ventilated ARDS patients. This produced a significant decrease in plateau pressure and driving pressure and significantly increased respiratory system compliance, which suggests less overdistension and less dynamic strain. more...
Published: 2016
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45. High Functional Stability of a Low-cost HBV DNA qPCR Primer Pair and Plasmid Standard.

Author: Aguiar J, García G, León Y, Canales E, Angel Silva J, Gell O, Estrada R, Morán I, Muzio V, Guillén G, Pentón E, and Aguilar JC
Abstract: Aim: We studied the functional stability of a primer pair and the standard curve based on a plasmid carrying full-length HBV genome, from a novel low-cost real-time quantitative polymerase chain reaction (qPCR) assay. The assay was developed at the Center for Genetic Engineering and Biotechnology (CIGB) in Havana, to quantify the serum hepatitis B virus (HBV) DNA from chronic HBV-infected (CHB) patients., Materials and Methods: In-house generated oligonucleotides and plasmids were incubated at 37°C during 1 month and compared with the same materials incubated at -20, 4, and 25°C during the same time in qPCR experiments., Results: This work shows that the oligonucleotide pair and the plasmid for the quantitative standard curve are functionally stable in severe temperature conditions during 1 month. Polymerase chain reaction amplification with both materials after its incubation 30 days at 37°C produced similar cycle threshold (CT) values and similar degree of sample quantifications compared with the same materials preserved using the conventional storage conditions at -20°C., Conclusion: These results are indicative of the robustness of this low-cost qPCR system for HBV DNA quantification. These results also support that this qPCR assay can be used as a low-cost technology in clinical studies to monitor the viral load changes of serum HBV DNA of CHB patients, which could be used by poor people of third world countries, where there are frequent blackouts and temperature changes that can hinder the primer and plasmid stability., How to Cite This Article: Aguiar J, García G, León Y, Canales E, Silva JA, Gell O, Estrada R, Morán I, Muzio V, Guillén G, Pentón E, Aguilar JC. High Functional Stability of a Low-cost HBV DNA qPCR Primer Pair and Plasmid Standard. Euroasian J Hepato-Gastroenterol 2016;6(1):19-24., Competing Interests: Source of support: Nil Conflict of interest: None more...
Published: 2016
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46. TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.

Author: Cebola I, Rodríguez-Seguí SA, Cho CH, Bessa J, Rovira M, Luengo M, Chhatriwala M, Berry A, Ponsa-Cobas J, Maestro MA, Jennings RE, Pasquali L, Morán I, Castro N, Hanley NA, Gomez-Skarmeta JL, Vallier L, and Ferrer J more...
Subjects: Adaptor Proteins, Signal Transducing genetics, Animals, Animals, Genetically Modified, Cell Differentiation, Cell Lineage, Cell Proliferation, Cells, Cultured, Computational Biology, DNA-Binding Proteins genetics, Databases, Genetic, Gene Expression Regulation, Developmental, Gene Regulatory Networks, Humans, Mice, Inbred C57BL, Nuclear Proteins genetics, Organogenesis, Pancreas embryology, Phenotype, Phosphoproteins genetics, RNA, Messenger metabolism, TEA Domain Transcription Factors, Time Factors, Transcription Factors genetics, YAP-Signaling Proteins, Zebrafish embryology, Zebrafish genetics, Zebrafish metabolism, Adaptor Proteins, Signal Transducing metabolism, DNA-Binding Proteins metabolism, Embryonic Stem Cells metabolism, Multipotent Stem Cells metabolism, Nuclear Proteins metabolism, Pancreas metabolism, Phosphoproteins metabolism, Signal Transduction, Transcription Factors metabolism
Abstract: The genomic regulatory programmes that underlie human organogenesis are poorly understood. Pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer and diabetes. We have now characterized the regulatory landscape of embryonic multipotent progenitor cells that give rise to all pancreatic epithelial lineages. Using human embryonic pancreas and embryonic-stem-cell-derived progenitors we identify stage-specific transcripts and associated enhancers, many of which are co-occupied by transcription factors that are essential for pancreas development. We further show that TEAD1, a Hippo signalling effector, is an integral component of the transcription factor combinatorial code of pancreatic progenitor enhancers. TEAD and its coactivator YAP activate key pancreatic signalling mediators and transcription factors, and regulate the expansion of pancreatic progenitors. This work therefore uncovers a central role for TEAD and YAP as signal-responsive regulators of multipotent pancreatic progenitors, and provides a resource for the study of embryonic development of the human pancreas. more...
Published: 2015
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47. Ventilatory strategies in obstructive lung disease.

Author: Parrilla FJ, Morán I, Roche-Campo F, and Mancebo J
Subjects: Airway Resistance physiology, Humans, Intubation, Intratracheal, Positive-Pressure Respiration, Pulmonary Disease, Chronic Obstructive physiopathology, Respiratory Insufficiency etiology, Severity of Illness Index, Pulmonary Disease, Chronic Obstructive therapy, Respiration, Artificial methods, Respiratory Insufficiency therapy
Abstract: Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation (EFL) due to progressive airflow obstruction. The various mechanisms that cause EFL are central to understanding the physiopathology of COPD. At the end of expiration, dynamic inflation may occur due to incomplete emptying the lungs. This "extra" volume increases the alveolar pressure at the end of the expiration, resulting in auto-positive end-expiratory pressure (PEEP) or PEEPi. Acute exacerbations of COPD may result in increased airway resistance and inspiratory effort, further leading to dynamic hyperinflation. COPD exacerbations may be triggered by environmental exposures, infections (viral and bacterial), or bronchial inflammation, and may result in worsening respiratory failure requiring mechanical ventilation (MV). Acute exacerbations of COPD need to be distinguished from other events such as cardiac failure or pulmonary emboli. Strategies to treat acute respiratory failure (ARF) in COPD patients include noninvasive ventilation (NIV), pressure support ventilation, and tracheal intubation with MV. In this review, we discuss invasive and noninvasive techniques to address ARF in this patient population. When invasive MV is used, settings should be adjusted in a way that minimizes hyperinflation, while providing reasonable gas exchange, respiratory muscle rest, and proper patient-ventilator interaction. Further, weaning from MV may be difficult in these patients, and factors amenable to pharmacological correction (such as increased bronchial resistance, tracheobronchial infections, and heart failure) are to be systematically searched and treated. In selected patients, early use of NIV may hasten the process of weaning from MV and improve outcomes., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.) more...
Published: 2014
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48. Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

Author: Pasquali L, Gaulton KJ, Rodríguez-Seguí SA, Mularoni L, Miguel-Escalada I, Akerman İ, Tena JJ, Morán I, Gómez-Marín C, van de Bunt M, Ponsa-Cobas J, Castro N, Nammo T, Cebola I, García-Hurtado J, Maestro MA, Pattou F, Piemonti L, Berney T, Gloyn AL, Ravassard P, Skarmeta JLG, Müller F, McCarthy MI, and Ferrer J more...
Subjects: Base Sequence, Chromatin genetics, Chromatin metabolism, Chromatin Immunoprecipitation, Diabetes Mellitus, Type 2 metabolism, Electrophoretic Mobility Shift Assay, Formaldehyde, Genome-Wide Association Study, Humans, Molecular Sequence Data, Sequence Analysis, RNA, Transcription Factors genetics, Web Browser, Diabetes Mellitus, Type 2 genetics, Enhancer Elements, Genetic genetics, Gene Expression Regulation genetics, Gene Regulatory Networks genetics, Islets of Langerhans metabolism, Transcription Factors metabolism
Abstract: Type 2 diabetes affects over 300 million people, causing severe complications and premature death, yet the underlying molecular mechanisms are largely unknown. Pancreatic islet dysfunction is central in type 2 diabetes pathogenesis, and understanding islet genome regulation could therefore provide valuable mechanistic insights. We have now mapped and examined the function of human islet cis-regulatory networks. We identify genomic sequences that are targeted by islet transcription factors to drive islet-specific gene activity and show that most such sequences reside in clusters of enhancers that form physical three-dimensional chromatin domains. We find that sequence variants associated with type 2 diabetes and fasting glycemia are enriched in these clustered islet enhancers and identify trait-associated variants that disrupt DNA binding and islet enhancer activity. Our studies illustrate how islet transcription factors interact functionally with the epigenome and provide systematic evidence that the dysregulation of islet enhancers is relevant to the mechanisms underlying type 2 diabetes. more...
Published: 2014
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49. Molecular diagnosis of bloodstream infections with a new dual-priming oligonucleotide-based multiplex PCR assay.

Author: Carrara L, Navarro F, Turbau M, Seres M, Morán I, Quintana I, Martino R, González Y, Brell A, Cordon O, Diestra K, Mata C, Mirelis B, and Coll P
Subjects: Humans, Oligonucleotides genetics, Prospective Studies, Sensitivity and Specificity, Bacteremia diagnosis, Multiplex Polymerase Chain Reaction methods
Abstract: Mortality from bloodstream infections (BSIs) correlates with diagnostic delay and the use of inappropriate empirical treatment. Early PCR-based diagnosis could decrease inappropriate treatment, improving patient outcome. The aim of the present study was to assess the clinical utility of this molecular technology to diagnose BSIs. We assessed a new dual-priming oligonucleotide-based multiplex PCR assay, the Magicplex Sepsis Test (MST) (Seegene), along with blood culture (BC). A total of 267 patients from the intensive care unit and haematology and emergency departments were enrolled. Clinical data were also used by physicians to determine the likelihood of infection. Ninety-eight (37 %) specimens were positive: 29 (11 %) by both the MST and BC, 29 (11 %) by the MST only, and 40 (15 %) by BC only. The proportion of agreement between the two methods was 73 % (Cohen's κ: 0.45; 0.28-0.6; indicating fair to moderate agreement). According to clinical assessment, 63 (64 %) positive specimens were considered BSIs: 23 (36 %) were positive by both the MST and BC, 22 (35 %) were positive only by BC, and 18 (29 %) were positive only by the MST. Thirty-eight (14 %) positive specimens by the MST and/or BC were considered as contaminants. Of 101 specimens collected from patients receiving antibiotics, 20 (20 %) were positive by the MST and 32 (32 %) by BC. Sensitivity and specificity were 65 % and 92 %, respectively, for the MST and 71 % and 88 %, respectively for BC. We concluded that the MST shows a high specificity but changes in design are needed to increase bacteraemia detection. For viability in clinical laboratories, technical improvements are also required to further automate the process. more...
Published: 2013
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50. Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.

Author: Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins T, Gmyr V, Pattou F, Kerr-Conte J, Piemonti L, Berney T, Hanley N, Gloyn AL, Sussel L, Langman L, Brayman KL, Sander M, McCarthy MI, Ravassard P, and Ferrer J more...
Subjects: Animals, Chromatin chemistry, Chromatin metabolism, DNA-Binding Proteins, Diabetes Mellitus, Type 2 pathology, Down-Regulation, Gene Expression Profiling, Genetic Loci, Humans, Mice, RNA, Messenger metabolism, Repressor Proteins genetics, Repressor Proteins metabolism, Trans-Activators genetics, Trans-Activators metabolism, Diabetes Mellitus, Type 2 metabolism, Insulin-Secreting Cells metabolism, RNA, Long Noncoding metabolism
Abstract: A significant portion of the genome is transcribed as long noncoding RNAs (lncRNAs), several of which are known to control gene expression. The repertoire and regulation of lncRNAs in disease-relevant tissues, however, has not been systematically explored. We report a comprehensive strand-specific transcriptome map of human pancreatic islets and β cells, and uncover >1100 intergenic and antisense islet-cell lncRNA genes. We find islet lncRNAs that are dynamically regulated and show that they are an integral component of the β cell differentiation and maturation program. We sequenced the mouse islet transcriptome and identify lncRNA orthologs that are regulated like their human counterparts. Depletion of HI-LNC25, a β cell-specific lncRNA, downregulated GLIS3 mRNA, thus exemplifying a gene regulatory function of islet lncRNAs. Finally, selected islet lncRNAs were dysregulated in type 2 diabetes or mapped to genetic loci underlying diabetes susceptibility. These findings reveal a new class of islet-cell genes relevant to β cell programming and diabetes pathophysiology., (Copyright © 2012 Elsevier Inc. All rights reserved.) more...
Published: 2012
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