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4. 2 years outcomes in patients with or without ARC-HBR criteria undergoing PCI with polymer-free biolimus coated stents: The Biofreedom France Study

Author

Garot, P., primary, Brunel, P., additional, Dibie, A., additional, Morelle, J.-F., additional, Abdellaoui, M., additional, Levy, R., additional, Carrié, D., additional, Karsenty, B., additional, Robin, C., additional, Berland, J., additional, Copt, S., additional, Sadozai, S., additional, Olroyd, K., additional, Morice, M.-C., additional, and Lipiecki, J., additional

Published
2023
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8. Clinical and genetic spectra of autosomal dominant tubulointerstitial kidney disease due to mutations in UMOD and MUC1

Author

Olinger, E, Hofmann, P, Kidd, K, Dufour, I, Belge, H, Schaeffer, C, Kipp, A, Bonny, O, Deltas, C, Demoulin, N, Fehr, T, Fuster, D G, Gale, D P, Goffin, E, Hodanova, K, Huynh-Do, Uyen, Kistler, Andreas, Morelle, J, Papagregoriou, G, Pirson, Y, Sandford, R, Sayer, J A, Torra, R, Venzin, C, Venzin, R, Vogt, B, Živná, M, Greka, A, Dahan, K, Rampoldi, L, Devuyst, Olivier, et al, University of Zurich, and Olinger, E

Subjects
2727 Nephrology, Nephrology, 570 Life sciences, biology, 610 Medicine & health, 10052 Institute of Physiology
Published
2020

9. The natural course of pregnancies in women with primary atypical haemolytic uraemic syndrome and asymptomatic relatives

Author

Timmermans, S., Werion, A., Spaanderman, M.E.A., Reutelingsperger, C.P.M., Damoiseaux, J., Morelle, J., Paassen, P. van, Timmermans, S., Werion, A., Spaanderman, M.E.A., Reutelingsperger, C.P.M., Damoiseaux, J., Morelle, J., and Paassen, P. van

Abstract

Contains fulltext : 229339.pdf (Publisher’s version ) (Open Access), Pregnancy has been linked to various microangiopathies, including primary atypical haemolytic uraemic syndrome (aHUS). Complement dysregulation, often linked to rare variants in complement genes, is key for primary aHUS to manifest and may play a role in pregnancy complications of the mother and fetus. The burden of such complications is unknown, making counselling of women with primary aHUS and asymptomatic relatives difficult. We analyzed the maternal and fetal outcomes of 39 pregnancies from 17 women with primary aHUS and two asymptomatic relatives. Seven out of 39 pregnancies were complicated by pregnancy-associated aHUS. Five out of 32 pregnancies not linked to pregnancy-associated aHUS were complicated by pre-eclampsia or HELLP. Rare genetic variants were identified in 10 women (asymptomatic relatives, n = 2) who had a total of 14 pregnancies, including 10 uncomplicated pregnancies. Thirty-five out of 39 pregnancies resulted in live birth. Eight out of 19 women had progressed to end-stage kidney disease, with an incidence of 2·95 (95% confidence interval, 1·37-5·61) per 100 person-years after the first pregnancy. Thus, we emphasized the frequency of successful pregnancies in women with primary aHUS and asymptomatic relatives. Pregnancies should be monitored closely. Rare genetic variants cannot predict the risk of a given pregnancy.

Published
2020

10. Impact of chronic obstructive pulmonary disease and dyspnoea on clinical outcomes in ticagrelor treated patients undergoing percutaneous coronary intervention in the randomized GLOBAL LEADERS trial

Author

Tomaniak, M. (Mariusz), Chichareon, P. (Ply), Takahashi, K. (Kuniaki), Kogame, N. (Norihiro), Modolo, R. (Rodrigo), Chang, C.C. (Chun Chin), Spitzer, E. (Ernest), Neumann, F.J., Plante, S. (Sylvain), Hernandez-Antolin, R. (Rosana), Jambrik, Z. (Zoltan), Gelev, V. (Valeri), Brunel, P. (Philippe), Konteva, M. (Mariana), Beygui, F. (Farzin), Morelle, J.-F. (Jean-Francois), Filipiak, K.J. (Krzysztof J.), Geuns, R.J.M. (Robert Jan) van, Soliman, O.I.I. (Osama Ibrahim Ibrahim), Tijssen, J.G.P. (Jan), Rademaker-Havinga, T.A.M. (Tessa), Storey, D. (David), Hamm, C. (Christian), Steg, P.G. (Philippe Gabriel), Windecker, S.W. (Stephan), Onuma, Y. (Yoshinobu), Valgimigli, M. (Marco), Serruys, P.W.J.C. (Patrick), Tomaniak, M. (Mariusz), Chichareon, P. (Ply), Takahashi, K. (Kuniaki), Kogame, N. (Norihiro), Modolo, R. (Rodrigo), Chang, C.C. (Chun Chin), Spitzer, E. (Ernest), Neumann, F.J., Plante, S. (Sylvain), Hernandez-Antolin, R. (Rosana), Jambrik, Z. (Zoltan), Gelev, V. (Valeri), Brunel, P. (Philippe), Konteva, M. (Mariana), Beygui, F. (Farzin), Morelle, J.-F. (Jean-Francois), Filipiak, K.J. (Krzysztof J.), Geuns, R.J.M. (Robert Jan) van, Soliman, O.I.I. (Osama Ibrahim Ibrahim), Tijssen, J.G.P. (Jan), Rademaker-Havinga, T.A.M. (Tessa), Storey, D. (David), Hamm, C. (Christian), Steg, P.G. (Philippe Gabriel), Windecker, S.W. (Stephan), Onuma, Y. (Yoshinobu), Valgimigli, M. (Marco), and Serruys, P.W.J.C. (Patrick)

Abstract

AIMS: To evaluate long-term safety and efficacy of ticagrelor monotherapy in patients undergoing percutaneous coronary interventions (PCIs) in relation to chronic obstructive pulmonary disease (COPD) at baseline and the occurrence of dyspnoea reported as adverse event (AE) that may lead to treatment non-adherence. METHODS AND RESULTS: This is a non-prespecified, post hoc analysis of the randomized GLOBAL LEADERS trial (n = 15 991), comparing the experimental strategy of 23-month ticagrelor monotherapy following 1-mon

Published
2020
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15. Die Abstoßungskrise : Ihre Bedeutung zum Verständnis der Histokompatibilität sowie in der Abwägung der Zweckmäßigkeit einer immunosuppressiven Behandlung

Author

Alexandre, G. P. J., Morelle, J., van Ypersele, Ch., Sokal, G., Coche, E., Allgöwer, M., editor, Bauer, K. H., editor, Block, W., editor, Brunner, A., editor, de la Camp, H. Bürkle, editor, Denk, W., editor, Derra, E., editor, Frey, E. K., editor, Linder, F., editor, v. Seemen, H., editor, and Zenker, R., editor

Published
1969
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22. Test Bench For Converters Reliability Studies For EV and HEV Electrical Vehicle Applications

Author

Bendjedia, M., Berthon, Alain, Gustin, Frédéric, Morelle J., M., Coquery, Gérard, Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) (FEMTO-ST), Université de Technologie de Belfort-Montbeliard (UTBM)-Ecole Nationale Supérieure de Mécanique et des Microtechniques (ENSMM)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Technologies Nouvelles (INRETS/LTN), and Institut National de Recherche sur les Transports et leur Sécurité (INRETS)

Subjects
[SPI.NRJ]Engineering Sciences [physics]/Electric power, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2009

23. Inverter Components Reliability Tests for Hybrid Electrical Vehicles, 6th International Power Electrics and Motion Control

Author

Berthon, Alain, Gustin, Frédéric, Bendjedia, M., Morelle J., M., Coquery, Gérard, Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) (FEMTO-ST), Université de Technologie de Belfort-Montbeliard (UTBM)-Ecole Nationale Supérieure de Mécanique et des Microtechniques (ENSMM)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Technologies Nouvelles (INRETS/LTN), and Institut National de Recherche sur les Transports et leur Sécurité (INRETS)

Subjects
[SPI.NRJ]Engineering Sciences [physics]/Electric power, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2009

24. Die Abstoßungskrise

Author

Alexandre, G. P. J., primary, Morelle, J., additional, van Ypersele, Ch., additional, Sokal, G., additional, and Coche, E., additional

Published
1969
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27. Reliability study under DC stress on mmW LNA, Mixer and VCO

Author

Ighilahriz, S., primary, Cacho, F., additional, Moquillon, L., additional, Razafimandimby, S., additional, Blanchet, F., additional, Morelle, J., additional, Corrao, N., additional, Huard, V., additional, Garcia, P., additional, Arnaud, C., additional, Fournier, J.M., additional, and Benech, P., additional

Published
2012
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42. Fast [<SUP>18</SUP>F]FDG synthesis by alkaline hydrolysis on a low polarity solid phase support<FNR HREF="fn1"></FNR> <FN ID="fn1">Parts of this work was presented at the XIIth International Symposium on Radiopharmaceutical Chemistry Uppsala, Sweden, June 15–19, 1997</FN>

Author

Lemaire, C., Damhaut, Ph., Lauricella, B., Mosdzianowski, C., Morelle, J.-L, Monclus, M., Naemen, J. Van, Mulleneers, E., Aerts, J., Plenevaux, A., Brihaye, C., and Luxen, A.

Abstract

The synthesis of 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) has been simplified by the use of a tC18 Sep Pak cartridge to effect purification and hydrolysis of the tetraacetylated [18F]fluoro-glucose compound ([18F]TAG). After radiolabelling, this derivative was trapped on a solid phase extraction (SPE) cartridge and the residual reaction solvent (CH3CN), reagents (K222, K2CO3,…) and by-products removed by washing the support with water. After this cleaning step, the acetyl groups were cleaved on the same tC18 column using 2N sodium hydroxide. This fast reaction proceeded near quantitatively (>98%) at room temperature in less than 2 min. The [18F]FDG was then recovered with a small amount of water, neutralized with a slight excess of 2N hydrochloric acid, buffered for pH with a citrate solution and finally purified on a neutral alumina oxide and a second tC18 column. After filtration, the radiochemical yield of this [18F]FDG isotonic solution after more than 100 production runs was found to be very reliable and reproducible (70±6% decay corrected). The synthesis time was about 22 min. Quality controls showed that the radiochemical purity was higher than 98% and in any case no [18F]FDM was detected. Only traces of 2-chloro-2-deoxy-glucose (ClDG) were found in the final sample (64±9 μg/ batch of 16 ml). [18F]FDG specific activity averaged between 1 and 20 Ci/µmol (EOS). No evaporation and use of ion retardation resin (AG11A8) are required. Moreover, this new approach is suitable for complete remote operation using available single use medical components. Copyright © 2002 John Wiley & Sons, Ltd.

Published
2002
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45. La Régulation du potassium hépatique

Author

UCL - MD/CHIR/CHEX - Unité de chirurgie expérimentale, Morelle, J., Kestens, Paul-Jacques, Haxhe, Jean-Jacques, Lambotte, Luc, UCL - MD/CHIR/CHEX - Unité de chirurgie expérimentale, Morelle, J., Kestens, Paul-Jacques, Haxhe, Jean-Jacques, and Lambotte, Luc

Abstract

Thèse d'agrégation de l'enseignement supérieur (Faculté de médecine) -- UCL, 1968

Published
1968

46. Etude clinique et expérimentale des sutures de l'aorte thoracique

Author

UCL - MD/CHIR/CHEX - Unité de chirurgie expérimentale, Morelle, J., Lantin, Fernand, UCL - MD/CHIR/CHEX - Unité de chirurgie expérimentale, Morelle, J., and Lantin, Fernand

Abstract

Thèse d'agrégation de l'enseignement supérieur (Faculté de médecine) -- UCL, 1963

Published
1963

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