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Your search keyword '"Murray, Jenny H."' showing total 4 results
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4 results on '"Murray, Jenny H."'

3. Methyl side-chain dynamics in proteins using selective enrichment with a single isotopomer

Author

Chaykovski, Michael M., Bae, Lynnette C., Cheng, Minn-Chang, Murray, Jenny H., and Tortolani, Kenneth E. ; Zhang, Rui ; Seshadri, Kothandaraman ; Brown, Jonathan Miles ; Homans, Steve W. ; Kalverda, Arnout P. ; Hsieh, Shih-Yang ; Findlay, John H.B.C. ;

Subjects
Proteins -- Conformation, Proteins -- Research, Amino acids -- Synthesis, Amino acids -- Research, Chemistry
Abstract

A chemical synthetic approach for the preparation of valine is presented by incorporating 13CHD2 isotopomers. The benefits of this approach in 13C side-chain relaxation measurements on the mouse major urinary protein selectively enriched with valine are illustrated.

Published
2003

4. 1H-filtered correlation experiments for assignment and determination of coupling constants in backbone labelled proteins.

Author

Giesen, Alexander W., Bae, Lynnette C., Barrett, Christa L., Chyba, Jason A., Chaykovsky, Michael M., Minn-Chang Cheng, Murray, Jenny H., Oliver, Ed J., Sullivan, Sarah M., Brown, Jonathan Miles, and Homans, Steve W.

Subjects
PROTEINS, AMINO acids, BIOMOLECULES, MAGNETIC resonance imaging, ORGANIC acids, PHYSICAL sciences
Abstract

The implementation of [13Cα,13C′,15N,2Hα] labelled amino acids into proteins allows the acquisition of high resolution triple resonance experiments. We present for the first time resonance assignments facilitated by this new labelling strategy. The absence of 1JCα,Cβ couplings enables us to measure 1JCα,C′ scalar and 1DCα,C′ residual dipolar coupling constants using modified HNCA experiments which do not suffer from sensitivity losses characteristic for 13C constant time experiments. [ABSTRACT FROM AUTHOR]

Published
2002
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