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Objective: Despite rapid advances in psychedelic sciences and the increasing number of countries legalizing psychedelics for the treatment of mental illnesses, the attitudes, knowledge and readiness of both mental health consumers and the general population remain largely unknown. Methods: A cross-sectional survey was conducted among Australians, targeting individuals with mental illness as potential mental health service users. A sub-sample of individuals free of mental illness was also surveyed to assess attitudes in the general population. Participants completed the Attitudes on Psychedelics Questionnaire, the Basic Knowledge of Psychedelics Test and a questionnaire by Corrigan et al. to capture attitudes toward psychedelic therapy by mental health service users. Results: Of the 502 respondents, 64.5% self-identified as having a mental illness. A significant proportion favored legalizing psychedelics for medical use (43%) and were open to their use (52.4%), yet fewer viewed their effects positively (24%) or considered them safe (33%). Most participants reported to be psychedelic naive (61%). Participants with mental illness had significantly more experience with psychedelics than participant free of mental illness (44.1% vs 29.7%). Experience, perceived knowledge and actual knowledge significantly predicted attitudes toward legalization, effects, risks and openness to psychedelics. Conclusions: While a large proportion of Australians are in favor of legalizing psychedelics for medical purposes, concerns about safety remain. People with self-identified mental illness, those with previous recreational psychedelic experience and those with greater knowledge of psychedelics were more likely to have positive attitudes toward psychedelics and psychedelic-assisted therapy. [ABSTRACT FROM AUTHOR]

Objective: To determine the functional outcome of minimally invasive plating osteosynthesis (MIPO) for distal femur fractures. Study Design: Description Study. Setting: Orthopedic Department of Allied Hospital, Faisalabad. Period: August 2020 to February 2021. Material & Methods: 115 patients of both gender with age ranging from 18 to 50 years and having lower 1/3 femur shaft fractures. Patients having nerve, vascular injury and opened fracture were excluded. All patients were treated with minimally invasive plating osteosynthesis (MIPO). Criteria for bone union was bridging callus formation across the fracture site in antero-posterior and lateral knees x-rays without evidence of loosening breakage and migration of the implants with painless weight bearing on that lower limb. IKDC score at 12 weeks after the procedure was used to assess the functional & clinical outcome. Results: These were excellent function result seen in 65 (56.51%) patients, good in 32 (27.83%), fair in 11 (9.57%) and poor out come in 07 (6.09%). 105 (91.30%) patients with distal 1/3 femur shaft fracture had achieved the union. Conclusion: Our study concluded minimally invasive plating osteosynthesis (MIPO) is an excellent method for the treatment of distal femoral shaft fractures. [ABSTRACT FROM AUTHOR]

This letter, published in the journal Australasian Psychiatry, discusses a case report of a 20-year-old Asian man who experienced recurrent serotonin syndrome after using cannabis. The patient had a history of bipolar disorder and was taking fluoxetine, melatonin, and lithium. On three separate occasions, he presented to the emergency department with symptoms consistent with serotonin syndrome, and cannabis use was found to be present each time. The authors suggest that there may be a potential link between high concentrate cannabis use and the development of serotonin syndrome, and caution that patients should be aware of the risks of combining cannabis with serotonergic medications. [Extracted from the article]