1. Sarcopenia and Vitamin D Deficiency in Patients with Crohn's Disease: Pathological Conditions That Should Be Linked Together
- Author
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Francesco Palmese, Pierluigi Cataleta, Maria Giulia Sama, Rossella Del Toro, Marco Domenicali, Giulia Di Marzio, Palmese F., Del Toro R., Di Marzio G., Cataleta P., Sama M.G., and Domenicali M.
- Subjects
Vitamin ,Crohn’s disease ,medicine.medical_specialty ,Sarcopenia ,Nutritional assess-ment ,skeletal muscle function ,Review ,Disease ,malnutrition ,Gastroenterology ,Inflammatory bowel disease ,vitamin D deficiency ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Crohn Disease ,inflammatory bowel disease ,Internal medicine ,Vitamin D and neurology ,Prevalence ,Medicine ,Humans ,TX341-641 ,030212 general & internal medicine ,Vitamin D ,Dietary Supplement ,Crohn's disease ,Nutrition and Dietetics ,business.industry ,Nutrition. Foods and food supply ,medicine.disease ,Vitamin D Deficiency ,Malnutrition ,chemistry ,nutritional assessment ,Dietary Supplements ,030211 gastroenterology & hepatology ,business ,Human ,Food Science - Abstract
Sarcopenia is a prevalent condition in patients with Crohn’s disease (CD), representing an independent predictor factor for the development of major postoperative complications. Thus, a proper assessment of the muscle strength, by using different validated tools, should be deemed an important step of the clinical management of these patients. Patients with CD are frequently malnourished, presenting a high prevalence of different macro- and micro-nutrient deficiencies, including that of vitamin D. The available published studies indicate that vitamin D is involved in the regulation of proliferation, differentiation, and regeneration of muscle cells. The relationship between vitamin D deficiency and sarcopenia has been extensively studied in other populations, with interesting evidence in regards to a potential role of vitamin D supplementation as a means to prevent and treat sarcopenia. The aim of this review was to find studies that linked together these pathological conditions.
- Published
- 2021