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1. Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity

Author

Sabelle, Stephane, Renard, Pierre-Yves, Pecorella, Karine, Suzzoni-Dezard, Sophie de, Creminon, Christophe, Grassi, Jacques, and Mioskowski, Charles

Subjects
Chemical research -- Analysis, Chemiluminescence -- Research, Cholinesterases -- Physiological aspects, Enzymes -- Physiological aspects, Neural transmission -- Regulation, Chemistry
Abstract

Research has been conducted on the acetylcholinestrase, the enzyme regulating neurotransmission. The activity of this enzyme has been investigated and the description of the 1,3-dioxetane chemiluminescent probe generated in search for a sensitive detection assay is presented.

Published
2002

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