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205 results on '"Pedrol, Enric"'

1. Didanosine, Lamivudine, and Efavirenz versus Zidovudine, Lamivudine, and Efavirenz for the Initial Treatment of HIV Type 1 Infection: Final Analysis (48 Weeks) of a Prospective, Randomized, Noninferiority Clinical Trial, GESIDA 3903

Author

Berenguer, Juan, González, Juan, Ribera, Esteban, Domingo, Pere, Santos, Jesús, Miralles, Pilar, Ribas, Ma. Angels, Asensi, Víctor, Gimeno, Juan Luis, Pérez-Molina, José Antonio, Terrón, José Alberto, Santamaría, Juan Miguel, and Pedrol, Enric

Published
2008
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2. Characteristics and outcome of HIV infection in gypsies in the Spanish VACH Cohort

Author

Teira, Ramón, Suárez-Lozano, Ignacio, Lozano, Fernando, Viciana, Pompeyo, Domingo, Pere, Galindo, Pepa, Geijo, Paloma, Terrón, Alberto, González, Juan, Cosín, Jaime, Ribera, Esteban, Roca, Bernardino, García-Alcalde, María L., Sánchez, Trinitario, Muñoz-Sánchez, Agustín, Vergara, Antonio, López-Aldeguer, José, Pedrol, Enric, Vidal, Francesc, Garrido, Myriam, and Santamaría, Juan M.

Published
2010
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4. Effect of genetic variants of CCR2 and CCL2 on the natural history of HIV-1 infection: CCL2-2518GG is overrepresented in a Cohort of Spanish HIV-1-infected subjects

Author

Vilades, Consuelo, Broch, Montserrat, Plana, Montserrat, Domingo, Pere, Alonso-Villaverde, Carlos, and Pedrol, Enric

Subjects
HIV infection -- Genetic aspects, HIV infection -- Natural history, HIV infection -- Risk factors, Genetic variation -- Analysis, Health
Abstract

A study was carried out to determine whether functionally active CCR2 and CCL2 genetic variants influence the risk of infection and disease progression in a cohort of white Spaniards. The distribution of CCL2 alleles showed no significant differences between groups but HIV-1-infected individuals had a significantly higher prevalence of the variant homozygous CCL2 GG genotype as compared to EUs.

Published
2007

6. Polymorphism of RANTES chemokine gene promoter is not associated with long-term nonprogressive HIV-1 infection of more than 16 years

Author

Vidal, Francesc, Peraire, Joaquin, Fontanet, Angels, Domingo, Pere, Broch, Monteserrat, Dalmau, David, Cairo, Mireia, Pedrol, Enric, Deig, Elisabeth, Montero, Milagros, Vilades, Consuelo, Knobel, Hernando, Gutierrez, Cristina, Sambeat, M. Antonio, Sirvent, Joan Josep, and Richart, Cristobal

Subjects
HIV infection -- Genetic aspects, Single nucleotide polymorphisms -- Research, Chemokines -- Research, Health
Abstract

A cross-sectional genetic association case-control study is conducted to examine the association of the polymorphisms of the RANTES chemokine gene promoter with the long-term nonprogressive HIV-1 infection. The analysis suggests that the single nucleotide polymorphisms (Snips) in the RANTES associated with the long-term nonprogressors (LNTPs) cannot exceed more than sixteen years.

Published
2006

8. Spanish HIV-1-infected long-term nonprogressors of more than 15 years have an increased frequency of the CX3CR1 249I variant allele

Author

Vidal, Francesc, Vilades, Consuedo, Domingo, Pere, Broch, Montserrat, Pedrol, Enric, Dalmau, David, Knobel, Hernando, Peraire, Joaquim, Gutierrez, Cristina, Sambeat, Antonia, Fontanet, Angels, Dieg, Elisabeth, Cairo, Mireia, Montero, Milagros, Richart, Cristobal, and Mallal, Simon

Subjects
Allelomorphism -- Research, Genetic variation -- Research, HIV infection -- Research, Genetic research, Health
Abstract

A study was conducted to determine whether functionally active CX3CR1 genetic variants are associated with long-term nonprogressive (LTNP) infection of less than 15 years in HIV-1 infected Spanish patients. The result shows that CX3CR1 249I variant allele is more frequent in Spanish HIV-1 infected LTNPs of less than 15 years, and the effect is independent of the presence of the CCR5(delta)32 allele.

Published
2005

9. Upregulatory mechanisms compensate for mitochondrial DNA depletion in asymptomatic individuals receiving stavudine plus didnosine

Author

Miro, Oscar, Marinez, Esteban, Giralt, Marta, Vilarroya, Francesc, Casademont, Jordi, Concepcion, Marisa Rodriguez de la, Lopez, Sonia, Gsttsbou, Gloria, Pedrol, Enric, Gatell, Josep M., and Cardellach, Francesc

Subjects
Stavudine -- Physiological aspects, Stavudine -- Chemical properties, Mitochondrial DNA -- Research, Antiviral agents -- Analysis, Antiviral agents -- Physiological aspects, Health
Abstract

The certainty that the homeostatic mechanisms are able to compensate for this mtDNA depletion in patients receiving stavudine plus didnosine(d4T+ ddI), an antiretroviral combination with great in vitro and in vivo capacity to decrease mtDNA is determined. The study concludes that treatment with ddT=ddI is associated with decreased mitochondrial mass and mtDNA content but that cytochrome c oxidase subnit II (COX-II) expression and COX activity remain unaltered.

Published
2004

12. Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection

Author

Martinez, Esteban, Arnaiz, Juan A., Podzamczer, Daniel, Dalmau, David, Ribera, Esteban, Domingo, Pere, Knobel, Hernando, Riera, Melcior, Pedrol, Enric, Force, Lluis, Llibre, Josep M., Segura, Ferran, Richart, Cristobal, Cortes, Cristina, Javaloyas, Manuel, Aranda, Miquel, Cruceta, Ana, Lazzari, Elisa de, and Gatell, Jose M.

Subjects
Abacavir -- Evaluation, HIV infection -- Drug therapy, Nevirapine -- Evaluation
Abstract

Nevirapine and efavirenz may be more effective AIDS drugs than abacavir, according to a study of 460 HIV patients. These drugs are often used instead of protease inhibitors because protease inhibitors have serious side effects. In this study, abacavir seemed to have fewer side effects than the other two drugs.

Published
2003

14. Mitochondrial Toxicogenomics for Antiretroviral Management: HIV Post-exposure Prophylaxis in Uninfected Patients

Author

Bañó, Maria, primary, Morén, Constanza, additional, Barroso, Sergio, additional, Juárez, Diana Luz, additional, Guitart-Mampel, Mariona, additional, González-Casacuberta, Ingrid, additional, Canto-Santos, Judith, additional, Lozano, Ester, additional, León, Agathe, additional, Pedrol, Enric, additional, Miró, Òscar, additional, Tobías, Ester, additional, Mallolas, Josep, additional, Rojas, Jhon F., additional, Cardellach, Francesc, additional, Martínez, Esteban, additional, and Garrabou, Gloria, additional

Published
2020
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16. Effectiveness and safety of didanosine, lamivudine and efavirenz versus zidovudine, lamivudine and efavirenz for the initial treatment of HIV-infected patients from the Spanish VACH cohort

Author

Crespo, Manuel, Ribera, Esteban, Suárez-Lozano, Ignacio, Domingo, Pere, Pedrol, Enric, López-Aldeguer, José, Muñoz, Agustín, Viladés, Consuelo, Sánchez, Trinitario, Viciana, Pompeyo, Teira, Ramón, García-Alcalde, María Luisa, Vergara, Antonio, Lozano, Fernándo, Galindo, María José, Cosin, Jaime, Roca, Bernardino, Terrón, Alberto, Geijo, Paloma, Vidal, Francesc, and Garrido, Myriam

Published
2009

21. HIV-1-Infected Long-Term Non-Progressors have Milder Mitochondrial Impairment and Lower Mitochondrially-Driven Apoptosis in Peripheral Blood Mononuclear Cells than Typical Progressors§

Author

Peraire, Joaquim, Miró, Òscar, Saumoy, Maria, Domingo, Pere, Pedrol, Enric, Villarroya, Francesc, Martínez, Esteban, López-Dupla, Miguel, Garrabou, Glória, Sambeat, Ma Antònia, Deig, Elisabet, Villarroya, Joan, Chacón, Matilde R., López, Sònia, Fontanet, Àngels, Holmstrom, Maija, Giralt, Marta, Gatell, Josep Ma, and Vidal, Francesc

Published
2007

26. Dyslipidaemia in HIV-infected women on antiretroviral therapy. Analysis of 922 patients from the Spanish VACH cohort

Author

Estrada Vicente, Geijo Paloma, Fuentes-Ferrer Manuel, Alcalde María, Rodrigo María, Galindo María, Muñoz Agustín, Domingo Pere, Ribera Esteve, Cosín Jaime, Viciana Pompeyo, Lozano Fernando, Terrón Alberto, Vergara Antonio, Teira Ramón, Muñoz-Sánchez Josefa, Roca Bernardino, Sánchez Trinitario, López-Aldeguer José, Deig Elisabeth, Vidal Francisco, Pedrol Enric, Castaño-Carracedo Manuel, Puig Teresa, Garrido Myriam, and Suárez-Lozano Ignacio

Subjects
Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Information concerning lipid disturbances in HIV-infected women on antiretroviral therapy (ART) is scarce. The objective of the study is to describe the lipid profile in a large cohort of HIV-infected women on contemporary ART and analyse differences between regimes and patient's characteristics. Methods Observational, multicentre, cross-sectional study from the Spanish VACH Cohort. 922 women on stable ART without lipid-lowering treatment were included. Results Median age was 42 years, median CD4 lymphocyte count was 544 cells/mm3, and 85.6% presented undetectable HIV-1 viral load. Median total cholesterol (TC) was 189 mg/dL (interquartile range, IQR, 165-221), HDL cholesterol 53 mg/dL (IQR, 44-64), LDL cholesterol 108 mg/dL (IQR, 86-134), and triglycerides 116 mg/dL (IQR, 85-163). Mean accumulated time on ART was 116 months; 47.4% were on NNRTI-based regimes, 44.7% on PI, and 6.7% on only-NRTI therapy. 43.8% were also hepatitis C (HCV) coinfected. Patients on PI treatment presented higher TC/HDL ratio than those on NNRTI (p < 0.001). Significantly higher HDL values were observed in NNRTI-treated patients. HCV-coinfected patients presented lower TC/HDL ratio than the non HCV-coinfected. In multivariate analysis, factors independently associated with TC/HDL ratio were age, triglyceride levels and HCV co-infection. PI treatment presented a non-significant association with higher TC/HDL ratio. Conclusions In HIV-infected women, the NNRTI-based ART is associated with a better lipid profile than the PI-based. Factors unrelated to ART selection may also exert an independent, significant influence on lipids; in particular, age, and triglyceride levels are associated with an increased TC/HDL ratio while HCV co-infection is associated with a reduced TC/HDL ratio.

Published
2011
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27. Effect of TNF-α genetic variants and CCR5Δ32 on the vulnerability to HIV-1 infection and disease progression in Caucasian Spaniards

Author

Peraire Joaquim, Broch Montserrat, Alonso-Villaverde Carlos, Domingo Pere, García Felipe, Olona Montserrat, Veloso Sergi, Viladés Consuelo, Plana Montserrat, Pedrol Enric, López-Dupla Miguel, Aguilar Carmen, Gutiérrez Mar, Leon Agathe, Tasias Mariona, Ma Gatell Josep, Richart Cristóbal, and Vidal Francesc

Subjects
Internal medicine, RC31-1245, Genetics, QH426-470
Abstract

Abstract Background Tumor necrosis factor alpha (TNF-α) is thought to be involved in the various immunogenetic events that influence HIV-1 infection. Methods We aimed to determine whether carriage of the TNF-α-238G>A, -308G>A and -863 C>A gene promoter single nucleotide polymorphisms (SNP) and the CCR5Δ32 variant allele influence the risk of HIV-1 infection and disease progression in Caucasian Spaniards. The study group consisted of 423 individuals. Of these, 239 were uninfected (36 heavily exposed but uninfected [EU] and 203 healthy controls [HC]) and 184 were HIV-1-infected (109 typical progressors [TP] and 75 long-term nonprogressors [LTNP] of over 16 years' duration). TNF-α SNP and the CCR5Δ32 allele were assessed using PCR-RFLP and automatic sequencing analysis methods on white blood cell DNA. Genotype and allele frequencies were compared using the χ 2 test and the Fisher exact test. Haplotypes were compared by logistic regression analysis. Results The distribution of TNF-α-238G>A, -308G>A and -863 C>A genetic variants was non-significantly different in HIV-1-infected patients compared with uninfected individuals: -238G>A, p = 0.7 and p = 0.3; -308G>A, p = 0.05 and p = 0.07; -863 C>A, p = 0.7 and p = 0.4, for genotype and allele comparisons, respectively. Haplotype analyses, however, indicated that carriers of the haplotype H3 were significantly more common among uninfected subjects (p = 0.04). Among the infected patients, the distribution of the three TNF-α genetic variants assessed was non-significantly different between TP and LTNP: -238G>A, p = 0.35 and p = 0.7; -308G>A, p = 0.7 and p = 0.6: -863 C>A, p = 0.2 and p = 0.2, for genotype and allele comparisons, respectively. Haplotype analyses also indicated non-significant associations. Subanalyses in the LTNP subset indicated that the TNF-α-238A variant allele was significantly overrepresented in patients who spontaneously controlled plasma viremia compared with those who had a detectable plasma viral load (genotype comparisons, p = 0.02; allele comparisons, p = 0.03). The CCR5Δ32 distribution was non-significantly different in HIV-1-infected patients with respect to the uninfected population (p = 0.15 and p = 0.2 for genotype and allele comparisons, respectively) and in LTNP vs TP (p = 0.4 and p = 0.5 for genotype and allele comparisons, respectively). Conclusions In our cohort of Caucasian Spaniards, TNF-α genetic variants could be involved in the vulnerability to HIV-1 infection. TNF-α genetic variants were unrelated to disease progression in infected subjects. The -238G>A SNP may modulate the control of viremia in LTNP. Carriage of the CCR5Δ32 variant allele had no effect on the risk of infection and disease progression.

Published
2010
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30. Lack of association of SDF-1 3'A variant allele with long-term nonprogressive HIV-1 infection is extended beyond 16 years

Author

Vidal, Francesc, Domingo, Pere, Knobel, Hernando, Dalmau, David, Sambeat, Antonia, Peraire, Joaquim, Broch, Montserrat, Pedrol, Enric, Vilades, Consuelo, Gutierrez, Cristina, and Richart, Cristobal

Subjects
Spaniards -- Health aspects, HIV infection -- Research, HIV infection -- Development and progression, Health
Abstract

The frequency of the SDF-1 3'A allelic variant in a cohort of white Spaniards made up of Human Immunodeficiency Virus (HIV)-1-infected long-term nonprogressors (LTNPs) older than 16 years of age, HIV-1-infected usual progressors and a group of healthy controls are studied. The results indicate that the SDF-1 3' A polymorphism is not a determinant of LTNP in HIV-1-infected Spanish patients.

Published
2005

31. Renal safety of coformulated tenofovir/emtricitabine vs other nucleoside analogues in combination therapy in antiretroviral-naive patients aged 50 years or older in Spain: The TRIP study

Author

Pedrol, Enric, primary, Caro-Murillo, Ana M., additional, Castaño, Manuel A., additional, Riera, Melchor, additional, Olalla, Julián, additional, Domingo, Pere, additional, Arazo, Piedad, additional, Gómez-Sirvent, Juan L., additional, Pulido, Federico, additional, Romero-Palacios, Alberto, additional, Aguirrebengoa, Koldo, additional, Vera, Francisco, additional, Ferrer, Pedro, additional, and Blanco Ramos, José R., additional

Published
2015
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33. Dyslipidaemia in HIV-infected women on antiretroviral therapy. Analysis of 922 patients from the Spanish VACH cohort

Author

Universitat Rovira i Virgili, Estrada, Vicente; Geijo, Paloma; Fuentes-Ferrer, Manuel; Garcia Alcalde, Maria Luisa; Rodrigo, Maria; Jose Galindo, Maria; Munoz, Agustin; Domingo, Pere; Ribera, Esteve; Cosin, Jaime; Viciana, Pompeyo; Lozano, Fernando; Terron, Alberto; Vergara, Antonio; Teira, Ramon; Munoz-Sanchez, Josefa; Roca, Bernardino; Sanchez, Trinitario; Lopez-Aldeguer, Jose; Deig, Elisabeth; Vidal, Francisco; Pedrol, Enric; Castano-Carracedo, Manuel; Puig, Teresa; Garrido, Myriam; Suarez-Lozano, Ignacio, Universitat Rovira i Virgili, and Estrada, Vicente; Geijo, Paloma; Fuentes-Ferrer, Manuel; Garcia Alcalde, Maria Luisa; Rodrigo, Maria; Jose Galindo, Maria; Munoz, Agustin; Domingo, Pere; Ribera, Esteve; Cosin, Jaime; Viciana, Pompeyo; Lozano, Fernando; Terron, Alberto; Vergara, Antonio; Teira, Ramon; Munoz-Sanchez, Josefa; Roca, Bernardino; Sanchez, Trinitario; Lopez-Aldeguer, Jose; Deig, Elisabeth; Vidal, Francisco; Pedrol, Enric; Castano-Carracedo, Manuel; Puig, Teresa; Garrido, Myriam; Suarez-Lozano, Ignacio

Abstract

Background: Information concerning lipid disturbances in HIV-infected women on antiretroviral therapy (ART) is scarce. The objective of the study is to describe the lipid profile in a large cohort of HIV-infected women on contemporary ART and analyse differences between regimes and patient's characteristics. Methods: Observational, multicentre, cross-sectional study from the Spanish VACH Cohort. 922 women on stable ART without lipid-lowering treatment were included. Results: Median age was 42 years, median CD4 lymphocyte count was 544 cells/mm3, and 85.6% presented undetectable HIV-1 viral load. Median total cholesterol (TC) was 189 mg/dL (interquartile range, IQR, 165-221), HDL cholesterol 53 mg/dL (IQR, 44-64), LDL cholesterol 108 mg/dL (IQR, 86-134), and triglycerides 116 mg/dL (IQR, 85-163). Mean accumulated time on ART was 116 months; 47.4% were on NNRTI-based regimes, 44.7% on PI, and 6.7% on only-NRTI therapy. 43.8% were also hepatitis C (HCV) coinfected. Patients on PI treatment presented higher TC/HDL ratio than those on NNRTI (p < 0.001). Significantly higher HDL values were observed in NNRTI-treated patients. HCV-coinfected patients presented lower TC/HDL ratio than the non HCV-coinfected. In multivariate analysis, factors independently associated with TC/HDL ratio were age, triglyceride levels and HCV co-infection. PI treatment presented a non-significant association with higher TC/HDL ratio. Conclusions: In HIV-infected women, the NNRTI-based ART is associated with a better lipid profile than the PI-based. Factors unrelated to ART selection may also exert an independent, significant influence on lipids; in particular, age, and triglyceride levels are associated with an increased TC/HDL ratio while HCV co-infection is associated with a reduced TC/HDL ratio.

Published
2011

34. HIV-1-infected long-term non-progressors have milder mitochondrial impairment and lower mitochondrially-driven apoptosis in peripheral blood mononuclear cells than typical progressors

Author

Medicina i Cirurgia, Universitat Rovira i Virgili, Vidal, Francesc, Gatell, Josep M, Giralt, Marta, Holmstrom, Maija, Fontanet, Angels, Lopez, Sonia, RODRÍGUEZ CHACÓN, MATILDE, Chacon, Matilde R, Villarroya, Joan, Deig, Elisabet, Sambeat, M Antonia, Garrabou, Gloria, Lopez-Dupla, Miguel, Martinez, Esteban, Villarroya, Francesc, Pedrol, Enric, Domingo, Pere, Saumoy, Maria, Miro, Oscar, Peraire, Joaquim, LÓPEZ DUPLA, JESÚS MIGUEL, PERAIRE FORNER, JOSÉ JOAQUIN, VIDAL MARSAL, FRANCISCO, Medicina i Cirurgia, Universitat Rovira i Virgili, Vidal, Francesc, Gatell, Josep M, Giralt, Marta, Holmstrom, Maija, Fontanet, Angels, Lopez, Sonia, RODRÍGUEZ CHACÓN, MATILDE, Chacon, Matilde R, Villarroya, Joan, Deig, Elisabet, Sambeat, M Antonia, Garrabou, Gloria, Lopez-Dupla, Miguel, Martinez, Esteban, Villarroya, Francesc, Pedrol, Enric, Domingo, Pere, Saumoy, Maria, Miro, Oscar, Peraire, Joaquim, LÓPEZ DUPLA, JESÚS MIGUEL, PERAIRE FORNER, JOSÉ JOAQUIN, and VIDAL MARSAL, FRANCISCO

Abstract

Mitochondrial parameters in peripheral blood mononuclear cells (PBMC) and their relationship with mitochondrially-driven PBMC apoptosis were investigated in a group of HIV-1-infected long-term nonprogressors (LTNP) and compared with untreated asymptomatic HIV-1 infected typical progressors (TP) and uninfected healthy controls (HC). Twenty-six LTNP, 27 TP and 31 HC were evaluated. Studies were performed in PBMCs. Mitochondrial DNA content (mtDNA) was assessed by quantitative real-time PCR. Activities of mitochondrial respiratory chain complexes (MRC) II, III and IV were determined by spectrophotometry. Caspase-3 activity was assessed by fluorimetry, and caspase-9 activation and Bcl-2 levels were assessed by immunoblotting. mtDNA abundance (p<0.05), MRC complex II (p<0.001), complex III (p<0.01) and complex IV (p=0.01) were lower in the TP group than in the HC group. In the LTNP group these parameters were similar to those of the HC group except for complex II, which was decreased (p<0.01). The PBMC of TP showed the highest overall apoptotic activation, since their caspase-3 activity was greater than that of HC (p<0.05) and LTNP. In the case of LTNP, however, the difference was non-significant. Caspase-9 and the caspase-9/Bcl-2 ratio were both over-expressed in TP compared to HC (p<0.01) and LTNP (p<0.05). Both of these measurements indicate that mitochondrially-driven apoptosis in TP is greater than in LTNP and HC. A relationship between mitochondrial damage and apoptotic activation was found in TP. Mitochondrial damage is associated with increased PBMC apoptosis in patients with active HIV-1 replication (TP). These abnormalities are slight or not present in LTNP.

Published
2007

36. MOXIFLOXACIN IN COMMUNITY-ACQUIRED PNEUMONIA

Author

Araujo, Olga, primary, Tasias, Maria, additional, Martinez, Rosan, additional, Cochez, Cyntia, additional, Sandrea, Juan Jose, additional, Thikomirova, Lidia, additional, Ramirez, Rafael, additional, Hernandez, Sebastian, additional, Ruiz, Sheila, additional, Delegido, Antonio, additional, Creus, Carles, additional, and Pedrol, Enric, additional

Published
2011
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38. Effect of TNF-α genetic variants and CCR5Δ32 on the vulnerability to HIV-1 infection and disease progression in Caucasian Spaniards

Author

Veloso, Sergi, primary, Olona, Montserrat, additional, García, Felipe, additional, Domingo, Pere, additional, Alonso-Villaverde, Carlos, additional, Broch, Montserrat, additional, Peraire, Joaquim, additional, Viladés, Consuelo, additional, Plana, Montserrat, additional, Pedrol, Enric, additional, López-Dupla, Miguel, additional, Aguilar, Carmen, additional, Gutiérrez, Mar, additional, Leon, Agathe, additional, Tasias, Mariona, additional, Ma Gatell, Josep, additional, Richart, Cristóbal, additional, and Vidal, Francesc, additional

Published
2010
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39. Genetic and Functional Mitochondrial Assessment of HIV-Infected Patients Developing HAART-Related Hyperlactatemia

Author

Garrabou, Glòria, primary, Morén, Constanza, additional, Gallego-Escuredo, Jose Miguel, additional, Milinkovic, Ana, additional, Villarroya, Francesc, additional, Negredo, Eugenia, additional, Giralt, Marta, additional, Vidal, Francesc, additional, Pedrol, Enric, additional, Martínez, Esteban, additional, Cardellach, Francesc, additional, Gatell, Josep Maria, additional, and Miró, Òscar, additional

Published
2009
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40. Efficacy and Safety of Switching From Boosted Lopinavir to Boosted Atazanavir in Patients With Virological Suppression Receiving a LPV/r-Containing HAART: The ATAZIP Study

Author

Mallolas, Josep, primary, Podzamczer, Daniel, additional, Milinkovic, Ana, additional, Domingo, Pere, additional, Clotet, Bonaventura, additional, Ribera, Esteve, additional, Gutiérrez, Félix, additional, Knobel, Hernando, additional, Cosin, Jaime, additional, Ferrer, Elena, additional, Arranz, José Alberto, additional, Roca, Victor, additional, Vidal, Francesc, additional, Murillas, Javier, additional, Pich, Judit, additional, Pedrol, Enric, additional, Llibre, Josep M, additional, Dalmau, David, additional, García, Isabel, additional, Aranda, Miquel, additional, Cruceta, Ana, additional, Martínez, Esteban, additional, Blanco, José L, additional, Lazzari, Elisa de, additional, and Gatell, José M, additional

Published
2009
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41. Safety of Switching Nevirapine Twice Daily to Nevirapine Once Daily in Virologically Suppressed Patients

Author

Podzamczer, Daniel, primary, Olmo, Montserrat, additional, Sanz, Jose, additional, Boix, Vicente, additional, Negredo, Eugenia, additional, Knobel, Hernando, additional, Domingo, Pere, additional, Pineda, Juan A, additional, Vilades, Consuelo, additional, Quero, Jose Hernandez, additional, Force, Lluis, additional, Lahoz, Juan Gonzalez, additional, Muñoz, Pepa, additional, Llibre, Josep M, additional, Mariño, Ana, additional, Ortega, Enrique, additional, Dalmau, David, additional, Gatell, Josep M, additional, Antón, Esperanza, additional, Sola, Julio, additional, Galindo, María J, additional, Pedrol, Enric, additional, Sanz, Jesus, additional, Lima, Javier Torre de, additional, and Flores, Juan, additional

Published
2009
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42. Influence of HAART on the Clinical Course of HIV-1-Infected Patients With Progressive Multifocal Leukoencephalopathy: Results of an Observational Multicenter Study

Author

Falcó, Vicenç, primary, Olmo, Montserrat, additional, del Saz, Sara Villar, additional, Guelar, Ana, additional, Santos, José R, additional, Gutiérrez, Mar, additional, Colomer, Daniel, additional, Deig, Elisabet, additional, Mateo, Gracia, additional, Montero, Milagro, additional, Pedrol, Enric, additional, Podzamczer, Daniel, additional, Domingo, Pere, additional, and Llibre, Josep M, additional

Published
2008
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43. Zidovudine/Lamivudine/Abacavir Plus Tenofovir in HIV-Infected Naive Patients: A 96-Week Prospective One-Arm Pilot Study

Author

Ferrer, Elena, primary, Gatell, Jose Maria, additional, Sanchez, Pochita, additional, Domingo, Pere, additional, Puig, Teresa, additional, Niubo, Jordi, additional, Cortes, Cristina, additional, Veloso, Sergio, additional, Pedrol, Enric, additional, Leon, Agathe, additional, Gutierrez, Mar, additional, and Podzamczer, Daniel, additional

Published
2008
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44. Asistencia urgente a pacientes con infección por el virus de la inmunodeficiencia humana: un problema que crece

Author

Pedrol, Enric, Fernández-Solà, J. (Joaquim), Masanés i Torán, Ferran, and Camp Herrero, J.

Subjects
Medical care, HIV (Viruses), Assistència sanitària, VIH (Virus), Urgències mèdiques, Medical emergencies
Abstract

La asistencia médica a pacientes con infección por el virus de la inmunodeficiencia humana (VIH) es habitualmente compleja debido a las características peculiares de esta enfermedad y al gran número de complicaciones infecciosas, metabólicas, neurológicas y en general, de todo tipo que presentan 1.3. Estos factores y la potencial gravedad que pueden representar, hace que con frecuencia estos pacientes soliciten asistencia médica en régimen urgente. La atención urgente a este colectivo de pacientes está poco organizada a nivel sanitario en nuestro país, ya que no se ha creado un dispositivo de asistencia sanitaria específica y la atención ambulatoria que reciben es claramente insuficiente.

Published
1992

46. In VivoEffects of Highly Active Antiretroviral Therapies Containing the Protease Inhibitor Nelfinavir on Mitochondrially Driven Apoptosis

Author

Miró, Òscar, primary, Villarroya, Joan, additional, Garrabou, Glòria, additional, López, Sònia, additional, de la Concepción, Marisa Rodríguez, additional, Pedrol, Enric, additional, Martínez, Esteban, additional, Giralt, Marta, additional, Gatell, Josep M, additional, Cardellach, Francesc, additional, Casademont, Jordi, additional, and Villarroya, Francesc, additional

Published
2005
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48. Efficacy and Safety of Once-Daily Combination Therapy with Didanosine, Lamivudine and Nevirapine in Antiretroviral-Naive HIV-Infected Patients

Author

Ribera, Esteban, primary, Rodríguez-Pardo, Dolors, additional, Rubio, Manuel, additional, Soler, Anna, additional, Pedrol, Enric, additional, Blanco, José L, additional, González, Alicia, additional, Crespo, Manel, additional, Falcó, Vicenç, additional, Ocaña, Imma, additional, Deig, Elisabeth, additional, Miró, Jose M, additional, and Pahissa, Albert, additional

Published
2005
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50. Results of a Study of Prolonging Treatment with Pegylated Interferon-α2A plus Ribavirin in HIV/HCV-Coinfected Patients with No Early Virological Response

Author

Fuster, Daniel, primary, Planas, Ramon, additional, Gonzalez, Juan, additional, Force, Lluís, additional, Cervantes, Manel, additional, Vilaró, Josep, additional, Roget, Mercè, additional, García, Isabel, additional, Pedrol, Enric, additional, Tor, Jordi, additional, Ballesteros, Angel L, additional, Salas, Anna, additional, Sirera, Guillem, additional, Videla, Sebastià, additional, Clotet, Bonaventura, additional, and Tural, Cristina, additional

Published
2005
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