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BackgroundThe System Usability Scale (SUS) is a common metric used to assess the usability of a system, and it was initially developed in English. The implementation of electronic systems for clinical counseling (eHealth and mobile health) is increasing worldwide. Therefore, tools are needed to evaluate these applications in the languages and regional contexts in which the electronic tools are developed. ObjectiveThis study aims to translate, culturally adapt, and validate the original English version of the SUS into a Spanish version. MethodsThe translation process included forward and backward translation. Forward translations were made by 2 native Spanish speakers who spoke English as their second language, and a backward translation was made by a native English speaker. The Spanish SUS questionnaire was validated by 10 experts in mobile app development. The face validity of the questionnaire was tested with 10 mobile phone users, and the reliability testing was conducted among 88 electronic application users. ResultsThe content validity index of the new Spanish SUS was good, as indicated by a rating of 0.92 for the relevance of the items. The questionnaire was easy to understand, based on a face validity index of 0.94. The Cronbach α was .812 (95% CI 0.748-0.866; P

Background: Patient safety climate constitutes an important element for quality improvement. Its current evidence base has been generated in hospital settings in developed countries. Studies in dentistry are limited. Objective: To systematically explore the evidence regarding assessing patient safety climate in dentistry. Methods: We developed a search strategy to explore MEDLINE, SCOPUS, and Web of Science databases from January 1st, 2002, to December 31st, 2022, to include observational studies on patient safety culture or patient safety climate assessment. Methodological features and item data concerning the dimensions employed for assessment were extracted and thematically analyzed. Reported scores were also collected. Results: Nine articles out of 5584 were included in this study. Most studies were generated from high‐income economies. Our analysis revealed methodological variations. Non‐randomized samples were employed (ranging from 139 to 656 participants), and response rates varied from 28% to 93.7%. Three types of measurement instruments have been adapted to assess patient safety climate. These mainly consisted of replacing words or rewording sentences. Only one study employed an instrument previously validated through psychometric methods. In general, patient safety climate levels were either low or neutral. Only one study reported scores equal to or greater than 75. Discussion: Despite diverse assessment tools, our two‐decade analysis reveals a lag compared with medicine, resulting in methodological variations for assessing patient safety climate. Collaboration is vital to elevate standards, prioritize patient safety across oral healthcare services, and advocate for integrating safety climate into local and national quality and patient safety strategies. [ABSTRACT FROM AUTHOR]

Copyright of Revista Oral is the property of Benemerita Universidad Autonoma de Puebla and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background and Aims: The treatment of recalcitrant facial flat warts has always been challenging for dermatologists. The pain related to the application of the different treatments, side effects and costs are determining factors in the choice of therapy. To date, it is known that oral isotretinoin administered at a dose of 0.5 mg/kg/day is effective and safe; However, the different adverse effects reported have a dose‐dependent behavior and they could limit their use. Our aim is to assess the effect of low‐doses of oral isotretinoin to reducing side effects in the complete removal of recalcitrant facial flat warts and the current evidence in this regard. Methods: An extensive literature review was conducted to identify articles relating to low doses of oral isotretinoin for recalcitrant flat warts treatment, regardless of design up to May 2023. Results: The literature search yielded eight articles of 324 reviewed meeting criteria. Isotretinoin was administered in doses of 0.1–0.5 mg/kg/day. Complete elimination of the lesions occurred in 65.13% of the patients and a partial response in 19.26%. Four relapses were documented at the 4‐month follow‐up. The most frequent adverse effect was cheilitis. Conclusion: We might consider low doses of oral isotretinoin for the treatment of recalcitrant facial flat warts in which side effects need to be reduced. However, current published works have several limitations, including small sample sizes, lack of control group and follow‐up periods. Larger, randomized, controlled studies are needed to verify the efficacy and safety of different doses of isotretinoin. [ABSTRACT FROM AUTHOR]

Keratinocyte cancer (KC) is the most common cancer worldwide. It is important to analyze the actual interventions that are available for the prevention of patients with a previous history of a KC. We aim to review the existent literature to assess the efficacy and safety of interventions to prevent KC in patients with a history of previous KC. We searched clinical trials in which the main outcome was the prevention of KC in patients with a previous history of KC using the strategy published in the International Prospective Register of Systematic Reviews (PROSPERO registry), CRD42016045981. We analyzed 18 clinical trials from which eight reported a benefit with their respective intervention but had methodological flaws and a variable risk of bias. Two clinical trials (regarding celecoxib and oral supplementation with nicotinamide) seemed to have the most beneficial results reducing the incidence of KC in treated groups. However, all of the studies are highly heterogeneous, which does not allow a meta‐analysis to be performed. New studies with greater epidemiological value should be conducted. [ABSTRACT FROM AUTHOR]

Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients. Effect of adding a low glycemic load and index diet over 12 weeks in the treatment of moderate acne: a randomized controlled trial GLO:DIF/01jan23:ijd16418-fig-0002.jpg PHOTO (COLOR): 2 ccstripPre- and postintervention photographs of patients allocated to experimental diet gl GLO:DIF/01jan23:ijd16418-fig-0003.jpg PHOTO (COLOR): 3 ccstripPre- and postintervention photographs of patients allocated to control diet gl This study indicates that in men with moderate acne, a diet with a low load and glycemic index as an adjuvant treatment to conventional pharmacological management has higher effectiveness compared with the control group. [Extracted from the article]

Background: Recalcitrant facial flat warts are caused by human papillomavirus and may persist for years despite treatment. Isotretinoin has demonstrated benefits in the treatment of recalcitrant, genital and common warts, but placebo-controlled trials have not been performed. Objective: To determine whether isotretinoin is safe and effective for recalcitrant facial flat warts. Methods: Isotretinoin 30 mg/day or placebo was administered to 16 and 15 patients, respectively, in double-blind, randomized fashion for 12 weeks. Cutaneous lesions were assessed and adverse events including serologic and ophthalmologic changes were recorded. It is considered that warts were recalcitrant if the patient was treated for at least 3 years with at least three of the following options: retinoids, 5-fluorouracil, imiquimod and cryotherapy using liquid nitrogen. Results: Each patient in the istotretinoin group showed complete clearance of all flat warts, while none of the patients in the placebo group showed any improvement ( p = 0.0001). The most frequent adverse event was cheilitis. There were no statistically significant changes in the laboratory findings. Limitations: The study design does not permit complete blinding of the dermatologist who can easily recognize the adverse effects of isotretinoin. The clinical findings, however, were so dramatic that this would not have impacted the findings. Another limitation of the study is a lack of follow-up to assess for recurrence after the drug was discontinued. Conclusions: Isotretinoin is an effective treatment for recalcitrant flat facial warts with a well-known, manageable safety profile. [ABSTRACT FROM AUTHOR]

The process of prescribing a medication is complex and includes: deciding whether it is indicated, choosing the best option, determining the dose and the appropriate management scheme to the physiological condition of the patient, and monitoring effectiveness and toxicity. We have to inform patients about the expected side effects and indications for requesting a consultation. Specific clinical questions were designed based on the acronym PICOST. The search was made in the specific websites of clinical practice guidelines, was limited to the population of older adults, in English or Spanish. We used 10 related clinical practice guidelines, eight systematic reviews and five meta-analyses. Finally, we made a search of original articles or clinical reviews for specific topics. The development and validation of clinical practice guidelines for "rational drug prescriptions in the elderly" is intended to promote an improvement in the quality of prescription through the prevention and detection of inappropriate prescribing in the elderly and, as a result of this, a decrease in the adverse events by drugs, deterioration of health of patients and expenditure of resources. [ABSTRACT FROM AUTHOR]

Background: potentially inappropriate prescribing (IP) includes the use of drugs that represent greater risk than benefi t to the patient, the STOPP-START instrument, allows its detection, the aim was to evaluate its utility. Methods: a descriptive cross-sectional study was performed. Randomly selecting records of older adults with at least one chronic degenerative disease, as last query had more than two months and have completed their monthly meeting at least four citations in the last 6 months were analyzed. Results: the fi les from 285 patients were reviewed, females were 60 %, and the mean age was 74 ± 6 years. A total of 1749 prescriptions included 126 different drugs. The prevalence of inappropriate prescribing was 55 % (95 % CI = 49-61) and 87 % polypharmacy (95 % CI = 83-91). The cardiovascular, endocrine and skeletal muscle system diseases had the highest number of prescriptions and inappropriate prescribing. It was detected the omission of one or more drugs listed in 72 % of 75 % specific clinical circumstances. Conclusions: the STOPP-START instrument is useful for detecting inappropriate prescribing. Also, the omission of indicated preventive treatments required for older adults with chronic degenerative diseases. [ABSTRACT FROM AUTHOR]

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The advance in the knowledge and technology is growing quickly and greater quantity, so it is difficult for the health professional to access to whole information that is generated every day on diagnostic and therapeutic strategies more effective, so the clinic practice guidelines (CPG) is a resource to support the updating of the health professional and support them in making clinical decisions. The CPG is also a better support to the manager of health services in making decisions regarding the strategies that have performed for the patient and less risk to the individual and collective health. They also support the response capacity of the medical units and hospitals and guide the planning of services to the optimization of the resources. This paper summarizes the methodology of a national project for the development of GPC coordinated by the Mexican Social Security Institute with the collaboration of more than 1200 health professionals of the institution in a great effort institutional update and make information accessible to the entire health sector, which also defines the steps to upgrade and maintain the updating of knowledge and technology expressed in them. [ABSTRACT FROM AUTHOR]

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives: To ascertain the prevalence of gastroesophageal reflux disease (GERD) in elderly people attending to family medicine clinics. Material and methods: the study was conducted by using a prospective design in which participants were randomly selected from a family medicine clinic located in Mexico City. The study was run from August to September 2003, and included patients aged sixty years or older, regardless of gender. They should not have cognitive damage, which was ascertained by the Folstein Mini Mental State Examination. Those patients that did not accept to participate and those having incomplete or illegible medical records were excluded. The socio-demographic characteristics test and Carlsson-Dent test were applied. The information about diagnosis, drugs prescriptions, and pharmacological and no pharmacological gastroesophageal protection was obtained from the medical charts and prescriptions. Results: 400 elderly patients were evaluated by using the Carlsson-Dent test. GERD prevalence was 25% (IC 95 % 21-29) the average age of patients with and without GERD was 68 ± 7 years and 70 ± 7 years respectively (p = .002). Women suffered GERD more frequently than men (p = 0.001). GERD diagnosis was not found in any of the reviewed medical charts. Antacids, histamine-2 receptor antagonists (H2 As) and were prescribed in 39% (IC 95 % 34-44) of patients with GERD and in 18% (IC 95 % 15-21) without GERD. Conclusions: Elderly patients attending to primary care facilities often have GERD symptoms, but they are not properly diagnosed or followed up. The Carlsson-Dent questionnaire is an alternative to identify GERD patients. [ABSTRACT FROM AUTHOR]

Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: In the systematic review The prevalence of thyroid disease in patients with vitiligo of 2012 a prevalence of autoimmune thyroid disease was estimated in 14.3%; 6.8% in children (5.79-12.7%) and 18.6% in adults (13.7-22.9%). OBJECTIVES: To critically analyze research papers and to identify key points to improve the methodological quality for future systematic reviews. MATERIAL AND METHOD: Critical reading based on criteria PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) and manual of Joanna Briggs Institute of Australia. RESULTS: The quality methodology of the systematic review analyzed is attached to the PRISMA principles; however, there is a deficiency in the estimation of results and there are insufficient data to evaluate the reproducibility. Prevalence recalculated with meta-analysis with random effects was 9.52 (IC95% 4.80-15.65) of autoimmune thyroid disease in children. CONCLUSIONS: A prevalence systematic review should cover at least 7 key points that are stated in the text. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To determine the epidemiology and clinical features of vitiligo in children. MATERIALS AND METHODS: Retrospective cohort from sample records of pediatric patients who attended consultation with the diagnosis of vitiligo from January 2016 to December 2020. Data analysis was performed with the SPSS program version 25. Frequencies were expressed in percentages for the description of qualitative variables, while the mean and standard deviation for the quantitative variables were estimated due to the normality of the data. RESULTS: Five hundred seventy-four patients with an average age of 8.7 years participated, the average age of onset of the disease was 8.47 years, the median time of evolution of the disease was 6 months, 50.5% were females and 49.5% were males; 56.4% presented non-segmental vitiligo and 43.6% segmental vitiligo; 27 patients had a positive family history for vitiligo; 7 patients associated emotional stress as a trigger and 7 of them traumatisms; 7 patients presented thyroid disease; 19.7% had other associated dermatoses. The most frequent associated dermatoses were acne, keratosis pilaris, atopic dermatitis and alopecia areata. CONCLUSIONS: A higher percentage of segmental vitiligo was found compared to other populations of children with vitiligo in other countries and compared with adults; the incidence of autoimmune diseases in the pediatric population was lower than reported in other series; these results can be reflected in a better prognosis of pediatric patients. [ABSTRACT FROM AUTHOR]

Background: HIV-infections are one of the most important worldwide problems of public health. Causal agent is a retrovirus, HIV 1, infecting preferently lymphocytes CD4 cooperators. Objective: To determine the dermatological manifestations affecting patients with HIV attended at Clinic of Sexual Transmitted Infections of Dermatological Center Dr. Ladislao de la Pascua, Mexico City, and its relation to lymphocytes CD4 amount. Material and method: A cross-sectional and retrolective study analyzed data from patients attended at Clinic of Sexually Transmitted Infections from 2005 to 2011, files from HIV-positive patients were reviewed, corroborated by serology; viral load, lymphocytes T CD4 and dermatological manifestations were assessed. Results: 1,594 patients from Clinic of Sexually Transmitted Infections were registered; from them, 280 were seropositive (16.6%), the highest number of cases (n=113) was found with cells CD4 between 200 and 499 (40.3%); 25% (70 patients) had a viral load higher than 55,000 copies/mL. Predominant dermatoses were from infectious origin, 316 cases, viral and mycotic infections predominated with viral load of 200 and 499 CD4. Conclusions: Infectious dermatosis predominated in our group of population, viral diseases, among them, condyloma acuminata, were the most frequent with 200-499 cells CD4, followed by superficial mycoses. A statistically significant difference in the correlation of dermatosis amount and lymphocytes CD4 was not confirmed. [ABSTRACT FROM AUTHOR]

Background: The patients with psoriasis and ungueal alterations ocurres between 10 to 67% according to the world literature and the results have not been concluyents because the authors reports different percentages. Objetive: To determine the frequency of in psoriatic patients with ungueals changes. Material and methods: prospective, transversal, descriptive trial, with 50 psoriatic patients who had ungueal alterations. We did clinical, micological examination and cutaneous biopsy. Results: We studied 32 women (64%) and 18 men (36%) with a media of age: 54 años. The predominant psoriasis was in plaques in 84%, palm and plantar 10% and scalp psoriasis 6%. The frequency of onychomycosis in psoriatic patients with ungueal alterations was the 34%. The ungueal alterations associates with onychomycosis was more frequent in the feet than the hands: 30% vs. 4% respectively. The subungueal distal and lateral onychomycosis was the predominant clinical variety. The subungueal hiperqueratosis associates with onychomycosis was the most frequent and significant with a p-valiu of 0.0006 and OR of 4.12. Between the 34% of the psoriatic patients with ungueal alterations and onychomycosis, the cultive was positive in the 59% and 80% was dermatophytes vs 20% Candida albicans. Between the dermatophytes, trichophyton rubrum was insolated in the 70% and trichophyton mentagrophytes in the 10%. Conclusions: the frequency of onychomycosis in psoriatic patients with ungueal alterations was the 34%. The dermatophytes dominated over the yeasts. [ABSTRACT FROM AUTHOR]

Background: Actinic keratoses are one of the most common causes of consultation with the dermatologist. Clinical practice guidelines are needed to establish the precise diagnosis and treatment options. Objective: To guide clinical decision making based recommendations based on the best evidence available and reducing variations in clinical practice in diagnosis and treatment of adult patients with AKs. Methods: Design: Research is acknowledged. We used the following search engines: PubMed, Ovid, Tripdatabase, MD consult, Clearinghouse, SUMSearch. Standardized sequence was established to search for practice guidelines. We found three guidelines which took many of the recommendations. For recommendations not included in the reference guides the search process was conducted in PubMed and Cochrane Library. The results were expressed as levels of evidence and grade of recommendation. Conclusions: The 5 - FU is the drug of choice for multiple AKs. Cryotherapy is considered first-line treatment only and hypertrophic queratosis actínicas and QA PDT is used for non-hyperkeratotic, face and neck, has good cosmetic results, with high costs. [ABSTRACT FROM AUTHOR]

To develop and validate a clinical tool to facilitate decision-making based on current best evidence for treating adults and children with vitiligo. Methods: Clinical questions were formulated and structured. We established a standardized sequence to search for practice guidelines for treatment of vitiligo. Three guides were found, two of which were used for this study. For those drugs not included in the guidelines taken as a reference search was conducted in PubMed and Cochrane Library Plus, Hinari and Ovid. The results were expressed as levels of evidence and grade of recommendation according to the characteristics of the study design and type. Conclusions: The recommendations in this guide will help evidence based decision-making standard for the treatment of vitiligo in order to increase the percentage of dermatologists that indicate a treatment based on current best evidence, stimulating scientific research. [ABSTRACT FROM AUTHOR]

Objective: To provide to the dermatologist an instrument to facilitate decision-making and to increase the effectiveness of the treatment of patients with pemphigus vulgaris. With the foregoing, it is intended to achieve proper control of the disease and therefore reduce morbidity and mortality. Methods: We established a standardized sequence to search for clinical practice guidelines and other useful scientific information. We found only one guide with level of evidence and grade of recommendation and used a systematic review and other items obtained from search engines: Cochrane, PubMed, Ovid, MD consult. Conclusions: Pemphigus vulgaris is an autoimmune blistering disease which, if not treated properly, may lead to the death of the patient, so it is important to have an instrument to facilitate decision-making in its treatment. [ABSTRACT FROM AUTHOR]