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Your search keyword '"Plasminogen pharmacology"' showing total 483 results

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483 results on '"Plasminogen pharmacology"'

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1. Identification of potent anti-fibrinolytic compounds against plasminogen and tissue-type plasminogen activator employing in silico approaches.

2. Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.

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3. Fibrinolysis in Cardiac Arrest Patients Treated with Hypothermia.

4. A novel recombinant human microplasminogen induced complete posterior vitreous detachment without morphological change of retina in juvenile rabbits.

5. Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study.

6. Catheter-directed thrombolytic infusion for thrombosed arteriovenous fistulas with a large clot burden: A case series.

7. bFGF stimulated plasminogen activation factors, but inhibited alkaline phosphatase and SPARC in stem cells from apical Papilla: Involvement of MEK/ERK, TAK1 and p38 signaling.

8. Fibrinolytic Changes in Women with Preeclampsia.

9. Plasminogen: an enigmatic zymogen.

10. Exogenous activation and inhibition of plasminogen/plasmin activity during in vitro maturation of bovine cumulus-oocyte complexes: A biological and spectroscopic approach.

11. Plasminogen/plasmin affects expression of glycolysis regulator TIGAR and induces autophagy in lung adenocarcinoma A549 cells.

12. Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface.

13. Plasminogen is a master regulator and a potential drug candidate for the healing of radiation wounds.

14. Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines.

15. Stimulation of Phagocytic Activity in Cultured Human Corneal Fibroblasts by Plasminogen.

16. Small size apolipoprotein(a) isoforms enhance inflammatory and proteolytic potential of collagen-primed monocytes.

17. The mannose 6-phosphate/insulin-like growth factor 2 receptor mediates plasminogen-induced efferocytosis.

18. Plasminogen-Dependent Collagenolytic Properties of Staphylococcus aureus in Collagen Gel Cultures of Human Corneal Fibroblasts.

19. Angio-3, a 10-residue peptide derived from human plasminogen kringle 3, suppresses tumor growth in mice via impeding both angiogenesis and vascular permeability.

20. Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1α and GRP78.

21. The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.

22. Plasmin and regulators of plasmin activity control the migratory capacity and adhesion of human T cells and dendritic cells by regulating cleavage of the chemokine CCL21.

23. High-level expression, purification, and enzymatic characterization of truncated human plasminogen (Lys531-Asn791) in the methylotrophic yeast Pichia pastoris.

24. [THE EFFECTS OF LYS-PLASMINOGEN ON HUMAN PLATELET SECRETION].

25. Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop.

26. Concentration of fibrin and presence of plasminogen affect proliferation, fibrinolytic activity, and morphology of human fibroblasts and keratinocytes in 3D fibrin constructs.

27. Study of the sites of plasminogen molecule which are responsible for inhibitory effect of Lys-plasminogen on platelet aggregation.

28. Cortical-layer-specific effects of PACAP and tPA on interneuron migration during post-natal development of the cerebellum.

29. Isolation and purification of recombinant human plasminogen Kringle 5 by liquid chromatography and ammonium sulfate salting-out.

30. t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions.

31. Plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice.

32. [Effects of Lys-form of plasminogen on platelet actin cytoskeleton].

33. Human plasminogen kringle 1-5 inhibits angiogenesis and induces thrombomodulin degradation in a protein kinase A-dependent manner.

34. Plasminogen controls inflammation and pathogenesis of influenza virus infections via fibrinolysis.

35. Anti-tumoural effects of PlgK1-5 are directly linked to reduced ICAM expression, resulting in hepatoma cell apoptosis.

36. Fibrin chain cross-linking, fibrinolysis, and in vivo sealing efficacy of differently structured fibrin sealants.

37. Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds.

38. Modification of cyclic NGR tumor neovasculature-homing motif sequence to human plasminogen kringle 5 improves inhibition of tumor growth.

39. Dual inhibition of plasminogen kringle 5 on angiogenesis and chemotaxis suppresses tumor metastasis by targeting HIF-1α pathway.

40. Plasminogen K5 activates mitochondrial apoptosis pathway in endothelial cells by regulating Bak and Bcl-x(L) subcellular distribution.

41. The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines.

42. Antiangiogenic kringles derived from human plasminogen and apolipoprotein(a) inhibit fibrinolysis through a mechanism that requires a functional lysine-binding site.

43. Enhanced activity of meprin-α, a pro-migratory and pro-angiogenic protease, in colorectal cancer.

44. High efficacy and minimal peptide required for the anti-angiogenic and anti-hepatocarcinoma activities of plasminogen K5.

45. Preparation and characterization of RGD tumour-homing-peptide-modified plasminogen K5.

46. The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice.

47. Efficacy of plasmin, microplasmin, and streptokinase-plasmin complex for the in vitro degradation of fibronectin and laminin- implications for vitreoretinal surgery.

48. Effects of simulated bleeding in an in vitro nasal fibroblast wound healing model.

49. SPARC suppresses apoptosis of idiopathic pulmonary fibrosis fibroblasts through constitutive activation of beta-catenin.

50. Recombinant kringle 5 from plasminogen antagonises hepatocyte growth factor-mediated signalling.