1. DNA origami design and implementation
- Author
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Popa, Laura Ioana, Dobre, Ana-Maria, Itcus, Corina, Amarioarei, Alexandru, Paun, Andrei, Paun, Mihaela, Pop, Felician, Tusa, Iris, Minh-Kha Nguyen, Kuzyk, Anton, Czeizler, Eugen, University of Bucharest, National Institute of Research and Development for Biological Sciences, Filara Biomed Srl, Department of Neuroscience and Biomedical Engineering, Åbo Akademi University, Aalto-yliopisto, and Aalto University
- Subjects
NANOSCALE ,nanotechnology ,nanostructure ,Perdix visualization ,SHAPES ,DNA origami ,FOLDING DNA ,DNA Romanian map - Abstract
Since its introduction in the early 2000s, DNA origami had a big impact on the development of nanotechnology by gathering numerous applications. During this time, many tools were designed and used to generate arbitrary shapes capable of self-assembly which make this technique more approachable. In this paper, we have created the map of Romania at nanoscale dimensions by using a new open-source software - PERDIX. For this purpose, we used a scaffold strand with a length of 6959 nucleotides and 162 staple strands with a variable length ranging between 20 and 63 nucleotides. All the computational tools that were used in this experiment are open-source and user-friendly.
- Published
- 2020