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In order to obtain a chlorogenic acid platinum complex, The intermediate Pt(C6H14N2)(H2O)2(NO3)2 solution was synthesized from Pt(C6H14N2)I2 and AgNO3, and it was treated with the anion exchange resin to give the key intermediate Pt(C6H14N2)(OH)2. The key intermediate was subsequently reacted with chlorogenic acid in butyl alcohol. The complex structure and component were characterized by elemental analysis, ESI-MS, 1H-NMR and IR and the anticancer activity was measured by MTT method. The result showed that its structure was consistent with the title compound and had inhibiting effect on the growth of tumor cell lines in vitro.

In order to obtain the mixed isobutylamine /cyclopentylamine platinum complexes with chloride and oxalic acid ions as leaving groups. The title compounds were synthetised from potassiumtetrachloroplatinate(II) by the reaction with potassium iodide, cyclopentylamine, isobutylamine, silver nitrate, potassium chloride, potassium oxalate monohydrate. The complexes structure and component were characterized by elemental analysis, ESI-MS, 1H-NMR and IR and the anticancer activity were measured by MTT method. The results showed that its structure was consistent with the title compound and had inhibiting effect on the growth of tumor cell lines in vitro.

In order to obtain a gallic acid platinum complex, the title compound was synthesed from cis-[Pt(Cyclohexylamine)]2I2 by the reaction with NH3, silver nitrate and gallic acid respectively. The complex structure and component were characterized by elemental analysis, ESI-MS, 1H-NMR and IR and the anticancer activity was measured by MTT method. The result showed that its structure was consistent with the title compound and had inhibiting effect on the growth of tumor cell lines in vitro.

In order to obtain a chlorogenic acid platinum complex, The intermediate Pt(C6H14N2)(H2O)2(NO3)2 solution was synthesized from Pt(C6H14N2)I2 and AgNO3, and it was treated with the anion exchange resin to give the key intermediate Pt(C6H14N2)(OH)2. The key intermediate was subsequently reacted with chlorogenic acid in butyl alcohol. The complex structure and component were characterized by elemental analysis, ESI-MS, 1H-NMR and IR and the anticancer activity was measured by MTT method. The result showed that its structure was consistent with the title compound and had inhibiting effect on the growth of tumor cell lines in vitro.

The reaction of cis-[Pt(NO(3))(2)(NH(3))(2)] and sodium glycolate yielded the title compound, [Pt(C(2)H(2)O(3))(NH(3))(2)]. The Pt(II) atom, coordinated by two N atoms of ammine and two O atoms of the carboxyl-ate and oxido groups of the glycolate ligand, is in a square-planar environment. In the crystal structure, mol-ecules are connected by inter-molecular N-H⋯O hydrogen bonds, forming a three-dimensional network.