1. Convenient one-pot access to 2 H -3-nitrothiochromenes from 2-bromobenzaldehydes, sodium sulfide and β-nitrostyrenes
- Author
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Thanh Binh Nguyen, Dinh Hung Mac, Thi Thu Huong Le, Quy Hien Le, Chitose Youhei, Institut de Chimie des Substances Naturelles (ICSN), and Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)
- Subjects
010405 organic chemistry ,[CHIM.ORGA]Chemical Sciences/Organic chemistry ,Organic Chemistry ,chemistry.chemical_element ,010402 general chemistry ,01 natural sciences ,Biochemistry ,Sulfur ,Combinatorial chemistry ,Sodium sulfide ,0104 chemical sciences ,Catalysis ,chemistry.chemical_compound ,Cascade reaction ,chemistry ,Transition metal ,Functional group ,[CHIM]Chemical Sciences ,Physical and Theoretical Chemistry ,SODIUM SULFIDE NONAHYDRATE ,ComputingMilieux_MISCELLANEOUS - Abstract
An efficient synthesis of 2H-3-nitrothiochromenes via a cascade reaction was established. Starting from commercially available o-bromobenzaldehydes and β-nitrostyrenes with sodium sulfide nonahydrate as an inexpensive sulfur source, various substituted thiochromenes were synthesized with high functional group tolerance without any added transition metal catalyst or additive.
- Published
- 2019
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