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41 results on '"Ranjit Pabbati"'

1. Bioremediation of heavy metals-contaminated sites by microbial extracellular polymeric substances – A critical view

Author

Venkateswar Reddy Kondakindi, Ranjit Pabbati, Priyanka Erukulla, Naga Raju Maddela, and Ram Prasad

Subjects
Bioremediation, Extracellular polymeric substances, Heavy metals, Contamination, Microorganisms, Environmental technology. Sanitary engineering, TD1-1066
Abstract

Heavy metal (HM) contamination in the atmosphere poses substantial threats to ecosystems. Traditional methods for the removal of HM-contaminated sites, such as physical and chemical treatments, often have limitations in terms of efficiency, cost, and potential negative impacts on the environment. As a result, there is growing interest in exploring alternative and sustainable approaches, such as bioremediation. Bioremediation is a promising technology that utilizes the inherent abilities of microorganisms to degrade or transform pollutants into less harmful forms. Microbial exopolysaccharides have gained attention as potential tools in bioremediation strategies due to their unique physicochemical properties and their ability to interact with heavy metals. This work aims to provide an overview of the role of microbial extracellular polymeric substances (EPS) in the bioremediation of HM-contaminated sites. First, the mechanisms by which EPS facilitates heavy metal sequestration are discussed. EPS can form metal-complexing agents, such as chelators and ion-binding sites, which enhance the immobilization and precipitation of heavy metals, reducing their bioavailability and toxicity. EPS can act as a protective barrier, shielding microorganisms from heavy metal stress and facilitating their survival and growth. Additionally, EPS production can be induced or enhanced in response to heavy metal exposure, potentially increasing the efficiency of bioremediation processes.

Published
2024
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2. Impact of Regenerative Agriculture on Soil Erosion

Author

Kodaparthi, Ashwitha, Ranjit, Pabbati, Deepu, P Gnana, Kaushik, Desavathi Manju, Valli, Lade Akshayani, Ashrutha, Pindi, Harihara, Jogipeta, Chepuri, Kalyani, Negm, Abdelazim M., Series Editor, Chaplina, Tatiana, Series Editor, Aransiola, Sesan Abiodun, editor, Babaniyi, Babafemi Raphael, editor, Aransiola, Adejoke Blessing, editor, and Maddela, Naga Raju, editor

Published
2024
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5. Microbial Enzymes in Nanoparticle Synthesis

Author

Menon, Katherine Georgina, Reddy, Kondakindi Venkateshwar, Ranjit, Pabbati, Sree, Nalam Renuka Satya, Prasad, Ram, Series Editor, Maddela, Naga Raju, editor, Rodríguez Díaz, Joan Manuel, editor, and Branco da Silva Montenegro, Maria Conceição, editor

Published
2023
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16. Quorum quenching a sustainable biofilm mitigation strategy

Author

Venkateswar Reddy Kondakindi, Renuka Satya Sree Nalam, Ranjit Pabbati, and Naga Raju Maddela

Subjects
Bioengineering, Applied Microbiology and Biotechnology, Biotechnology
Abstract

Globally, over dosage of antibiotics has substantial impact on both human health and environment. Spread of antibiotics usage led to the virulent multidrug resistant pathogen emergence which was mostly contributed by Quorum Sensing (QS), a network phenomenon where bacteria communicate. It plays as an effective strategy ultimately resulting in antibiotic resistance, biofilm formation, bioluminescence, virulence etc. Biofilm formed by bacteria is rigid, selfdefensive, complicated which makes it more infectious in the living host. It suggests a promising strategy to break this strong intracellular communication i.e. quenching quorum sensing or simply Quorum Quenching (QQ). This review projects a brief outline on how bacteria communicate, molecules involved in this phenomenon, what makes a biofilm intact, the QS systems involved and Quorum quenching mechanism.

Published
2022

18. Quorum Quenching : A Chemical Biological Approach for Microbial Biofilm Mitigation and Drug Development

Author

Naga Raju Maddela, Ranjit Pabbati, Venkateswar Reddy Kondakindi, Naga Raju Maddela, Ranjit Pabbati, and Venkateswar Reddy Kondakindi

Subjects
Drug development, Quorum sensing (Microbiology), Drug resistance in microorganisms
Abstract

Antibiotic resistance is a global health concern. Strains of pathogenic microorganisms that have developed resistance to multiple antibiotics, such as MRSA, are extremely difficult to treat, and alternative methods for tackling pathogenic microorganisms are in demand. One potential target for new therapeutics is inhibition of quorum sensing: how microorganisms communicate and form biofilms in a density-dependent manner. Inhibiting this system via ‘quorum quenching'(QQ) is a promising route to new pharmaceuticals and for controlling biofilm formation and growth. Quorum sensing also provides interesting possibilities in synthetic biology for producing novel products, biosensors, bioactive molecules, and so on. This book covers the biology of quorum sensing and quenching, and potential sources of QQ enzymes and other inhibitors, as well as an overview of their mechanism and potential biotech applications. The book also covers the potential for new drug development from QQ, covering a range of related topics including protein engineering, imaging and computational studies, and integrated systems. This book is an ideal companion to researchers in chemical biology and medicinal chemistry, particularly those interested in biofilm formation, quorum sensing, novel antimicrobial development, synthetic biology and enzymology.

Published
2024

19. Nanoparticles for Biofilm Control

Author

Firdoz Shaik, Ranjit Pabbati, Venkateswar Reddy Kondakindi, and Moulika Aerupula

Subjects
biology, Biocompatibility, medicine.drug_class, Chemistry, Microorganism, Antibiotics, Biofilm, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Antimicrobial, Bacterial cell structure, Microbiology, Extracellular polymeric substance, medicine, Bacteria
Abstract

Microorganisms of planktonic types have emerged into biofilm structures by acquiring the ability to attach to the surfaces. The extracellular polymeric substances may play a vital role in anchoring the biofilm onto the surface and also protect it from various antibiotics making it highly resistant. This type of survival is procured by species of bacteria, fungi and protists. These biofilms pose numerous hazards to the human health and environment. Over 80% of the diseases are caused by the biofilms which include colorectal cancer, oral infections, periodontitis, cystic fibrosis and many others. Different strategies have been developed to eliminate the biofilms like the use of nano-sized particles. These nanoparticles provide antimicrobial properties and can also be used as a delivery system of the antibiotics with high stability and good biocompatibility. The high surface-area-to-volume ratio makes the nanoparticles to have high contact surface to the bacterial cell membrane and hence plays an efficient therapeutic way in treating the biofilms. In this review, we discuss the various diseases caused by the biofilm and different antibiofilm strategies using the nanomaterials. There is no doubt that the upcoming antibiofilm strategy which uses nanoscience can gain an ultimately new hope in advancements of coping with bacterial infections and resistance.

Published
2021

20. Epidemiology of COVID-19: Special Emphasis on Nanoscience and Its Implications

Author

Jaime Humberto Flores Garcia, Ranjit Pabbati, Venkateswar Reddy Kondakindi, and Afreen Fathima

Subjects
medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Infectious disease (medical specialty), Transmission (medicine), Political science, Epidemiology, Pandemic, Global health, medicine, Nanotechnology, Disease, medicine.disease_cause, Coronavirus
Abstract

Coronavirus disease 2019 (COVID-19) is a highly contagious pathogenic viral infection caused by SARS-Cov-2. Coronavirus seems to have taken a popular role in the twenty-first century. The first instance of COVID-19 which was reported in Hubei province, Wuhan, China, has now spread to the entire world by human-to-human transmission. The World Health Organization (WHO) declared this infectious disease as a pandemic. Currently this pandemic has created a global health crisis. In this chapter, we analysed the epidemiological characteristics, i.e. occurrence, distribution and transmission of disease in different countries, laboratory diagnosis, prevention, control and treatment of COVID-19. The main objective of this chapter is to provide the latest insights over nanotechnology and its implications in the diagnosis, treatment, prevention and control of COVID-19. In this direction, several emerging issues such as optical biosensor nanotechnology, respiratory masks, Nanofibers Membrane Technology, etc. We are in opinion that this chapter will provide useful insights towards understanding the role of nanotechniques to combat COVID-19.

Published
2021

21. Applications of Nanomaterials in Biomedical Engineering

Author

Firdoz Shaik, Venkateswar Reddy Kondakindi, and Ranjit Pabbati

Subjects
Engineering, business.industry, Nanoparticle, Nanotechnology, business, Nanomaterials, Characterization (materials science)
Abstract

In recent years, we have witnessed the revolutionary changes brought by nanotechnology in many fields. Nanomaterials are the building blocks of nanotechnology. Nanomaterials exhibit unique properties which are absent in bulk materials. Among nanomaterials, noble metal nanoparticles (NMNs) have been attracted due to their enchanting optical and chemical properties. At present, NMNs have enormous applications including catalysis, biosensors, bioimaging, theranostics, antimicrobial, cosmetics and medical appliances, and many others. In this book chapter, we have discussed briefly about the current scenario of nanotechnology, synthetic strategies of nanoparticles including top-down, bottom-up and biological approaches, characterization techniques, optical properties and different applications of nanoparticles in medical biotechnology.

Published
2021

22. List of contributors

Author

Aguilar, Cristóbal N., Akhtar, Nahid, Al-Tawaha, Abdel Rahman, Ali, Elham M., Ali, Omar Aweiss, Alves dos Santos, Angela, Alves Júnior, Sérgio Luiz, Américo-Pinheiro, Juliana Heloisa Pinê, Aransiola, S.A., Bastidas Barranco, Marlón José, Behera, Sudhanshu S., Bhattacharya, Sayan, Biswas, Protha, Boro, Manswama, Buitrón, Germán, Bursal, Ercan, Cabello-Galindo, Alejandra, Camargo, Aline Frumi, Chairez, Isaac, Chauhan, Indu, Chibani, Atef, Chopra, Muskaan, Chopra, Chirag, Chávez-González, Mónica L., Das, Pranjal P., Das, Urmimala, Das, Tuyelee, Dehane, Aissa, Dey, Shibam, Dey, Abhijit, Dey, Satarupa, Dhara, Simons, Dongare, Prajwal P., Duarah, Prangan, El-Chaghaby, Ghadir Aly, El-Sheekh, Mostafa M., Elshobary, Mostafa, Fawzy, Mustafa A., Ghorai, Mimosa, Ghosh, Sougata, Ghosh, Arabinda, Giraldo, Liliana, Gomaa, Mohamed, González-Fernández, Cristina, Gurav, Ranjit, Haldar, Dibyajyoti, Hansdah, Bishnupriya, Haq, Ikram ul, Helena dos Santos, Laura, Hwang, Sangchul, Jadhav, Rahul, Jadhav, Jyoti, Kamilya, Priyanka, Kumar, Kondragunta Prasanna, Kumar, Vineet, Kumar, Subrat, Leh-Togi Zobeashia, S.S., Machado-Cepeda, Samanta, Maddela, Naga Raju, Mandal, Sujata, Martínez Gil, José Manuel, Mazumder, Ishanee, Merouani, Slimane, Michelon, William, Moreno-Piraján, Juan Carlos, Mukhtar, Hamid, Mulla, Sikandar I., Nawaz, Ali, Nemdili, Leila, Nongdam, Potshangbam, Panda, Sandeep Kumar, Patel, Hiren K., Patel, Nidhi P., Pathak, Sagarjyoti, Pattnaik, Ritesh, Pawar, Hitesh S., Perarasu, V.T., Purkait, Mihir Kumar, Quijano, Guillermo, Quratulain, Ranjit, Pabbati, Rashad, Sayed, Ravinder, Palvi, Ray, Ramesh C., Reddy, Kondakindi Venkateswar, Rekha, Pawan, Remya, Neelancherry, Reyes, Ricardo Vivas, Rodríguez-Jasso, Rosa M., Rosero-Chasoy, Gilver, Roy, Chandrashish, Ruiz, Héctor A., Samanta, Niladri S., Saravanathamizhan, R., Sarkar, Bishwarup, Satya Sree, Nalam Renuka, Saxena, Rohit, Scapini, Thamarys, Shah, Maulin P., Shaheen, Falak, Shalaby, Emad A., Shanab, Sanaa M.M., Sharma, Vivek, Sharma, Indu, Sher, Farooq, Singh, Soumya, Singh, Shalini, Singh, Reena, Singh, Lovjeet, Sontakke, Ankush D., Taneja, Tanvi, Thongmee, Sirikanjana, Tiwari, Prashnasa, Treichel, Helen, Valekar, Navanath, Verma, Anil Kumar, Vetriselvan, K., Viancelli, Aline, Victor-Ekwebelem, M.O., Wani, Atif Khurshid, and Zambare, Vasudeo

Published
2023
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25. Essential oils, herbal extracts and propolis for alleviating Helicobacter pylori infections: A critical view.

Author

Reddy, Kondakindi Venkateswar, Sree, Nalam Renuka Satya, Ranjit, Pabbati, Maddela, Naga Raju, Kumar, Vivek, Jha, Priyanka, Prasad, Ram, and Radice, Matteo

Subjects
*PHYTOCHEMICALS, *HELICOBACTER pylori infections, *ESSENTIAL oils, *SAPONINS, *MULTIDRUG resistance in bacteria, *PROPOLIS, *HELICOBACTER pylori
Abstract

Helicobacter pylori is classified as Class I human carcinogen, is known for gastric, peptic duodenal ulcers and other gastrointestinal tract disorders. The treatment against H. pylori involving triple therapy with the use of a proton pump inhibitor and the combination of two different antibiotics. This approach has not been successful, but has led to some emerging therapies (e.g. second eradication, quadruple, sequential), which are also not very effective against H. pylori as this bacterium has multidrug resistance. This situation warrants discovering alternative therapeutic strategies against H. pylori by using natural products with low or no side effects. This review summarizes the antimicrobial activity of essential oils (EOs) of different aromatic plants against H. pylori related infections. More than twenty EOs and herbal extracts have been identified as potential natural products against H. pylori. Chemical constituents of these EOs and herbal extracts were found to be tannins, terpenoids, glycosides, phenolic compounds, flavonoids, alkaloids, saponins, amino acids, reducing sugars, and proteins. [Display omitted] • Plant essential oils and herbal extracts are effective against multi drug resistant H. pylori. • Apitherapy is another natural alternative with effective anti H. pylori activity. • Combination of EOs alone or with others unlock their potential anti-H. pylori activities. • Nano encapsulation enhances the EOs efficiencies in acting at precise targe location. • Unique resin from beehive i.e. Propolis regarded as the future anti-H. pylori therapeutic. [ABSTRACT FROM AUTHOR]

Published
2023
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