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159 results on '"Raoul, Gwénaël"'

38. Surgical bone augmentation procedures for oral rehabilitation of patients with oligodontia: a systematic review

Author

Thuaire, Antoine, Nicot, Romain, Raoul, Gwénaël, Lauwers, Ludovic, CIC CHU ( Lille)/inserm, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 (MBLC - ADDS), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)

Subjects
[SDV]Life Sciences [q-bio]
Abstract

International audience; Oligodontia is a developmental dental anomaly defined by the absence of 6 or more permanent teeth, excluding the third molars. We performed a review with a systematic approach and proposed a guideline for the choice of the bone augmentation surgery. The different bone augmentation technique terms were searched in the PubMed and Science Direct database. Clinical studies were eligible if they reported on pre-implant surgery in patients with oligodontia. The database search yielded 400 studies after duplicates removed. Thirty studies were finally included, involving 410 patients. Sixty-three sinus lifts were performed in 37 patients with no failure. Thirteen out of 33 patients with iliac bone transplantation and two out of 24 with parietal bone transplantation had resorption, one out of 4 patients who received allogeneic bone block had complete failure. Seventy-eight patients underwent guided bone regeneration, none had bone loss. No failure was found with the alveolar distraction osteogenesis technique. Four out of thirteen patients developed permanent hypoesthesia after inferior alveolar nerve transposition. The cumulative implant survival rate was 94.4% after bone augmentation procedures. Extensive edentulous areas should be grafted with parietal bone, as iliac grafts present a greater risk of resorption. Smaller edentulous areas should be treated by endobuccal harvesting or guided bone regeneration. Osteogenesis distraction and nerve transposition are effective surgeries for medium-to-large mandibular edentulous spaces. The implant survival rate is not significantly different between implants placed in grafted and nongrafted bone, the appropriate choice of bone augmentation technique can reduce the risk of peri‑implant bone resorption.

Published
2022

42. ACTN3 genotype influences masseter muscle characteristics and self‐reported bruxism.

Author

Nicot, Romain, Raoul, Gwénaël, Vieira, Alexandre R., Ferri, Joël, and Sciote, James J.

Subjects
*SALIVA analysis, *ORTHOGNATHIC surgery, *SELF-evaluation, *MASSETER muscle, *GENETIC polymorphisms, *MALOCCLUSION, *GENOTYPES, *GENES, *DESCRIPTIVE statistics, *TEMPOROMANDIBULAR disorders, *BRUXISM, *PHENOTYPES
Abstract

Objectives: Main aim of the study was to explore the association between genetic polymorphisms in ACTN3 and bruxism. Secondary objectives included masseter muscle phenotypes assessment between bruxers and non‐bruxers and according to genetic polymorphisms in ACTN3. Materials and Methods: Fifty‐four patients undergoing orthognathic surgery for correction of their malocclusion were enrolled. Self‐reported bruxism and temporomandibular disorders status were preoperatively recorded. Saliva samples were used for ACTN3 genotyping. Masseter muscle samples were collected bilaterally at the time of orthognathic surgery to explore the muscle fiber characteristics. Results: There were significant differences in genotypes for rs1815739 (R577X nonsense) (p = 0.001), rs1671064 (Q523R missense) (p = 0.005), and rs678397 (intronic variant) (p = 0.001) between bruxers and non‐bruxers. Patients with self‐reported bruxism presented a larger mean fiber area for types IIA (p = 0.035). The mean fiber areas in individuals with the wild‐type CC genotype for rs1815739 (R577X) were significantly larger for type IIA fibers (1394.33 μm2 [572.77 μm2]) than in those with the TC and TT genotypes (832.61 μm2 [602.43 μm2] and 526.58 μm2 [432.21 μm2] [p = 0.014]). Similar results for Q523R missense and intronic variants. Conclusions: ACTN3 genotypes influence self‐reported bruxism in patients with dentofacial deformity through specific masseter muscle fiber characteristics. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Use of 3D printed models in student education of craniofacial traumas

Author

Romain Nicot, Joël Ferri, Matthias Schlund, Raoul Gwénaël, Thomas Roland-Billecart, Didier Gosset, and Charles Druelle

Subjects
3d printed, Tessellation (computer graphics), medicine.medical_specialty, Computer science, Craniofacial trauma, 030229 sport sciences, 030206 dentistry, Comprehension, Fractures, Bone, 03 medical and health sciences, DICOM, 0302 clinical medicine, Printing, Three-Dimensional, ComputingMilieux_COMPUTERSANDEDUCATION, medicine, Oral and maxillofacial surgery, Humans, Medical physics, Oral Surgery, Craniofacial, Students, Education, Dental, ComputingMethodologies_COMPUTERGRAPHICS, Haptic technology
Abstract

A low-cost 3D printed model has been introduced into the oral and maxillofacial surgery teaching program of undergraduate students to improve education and mechanical comprehension of craniofacial trauma. Steps of the 3D printed haptic model building process are listed. 3D printed models of facial fractures were obtained from Data Imaging and Communications in Medicine (DICOM) data. Computed Aided Design and Manufacturing (CAD-CAM) freeware was used to create new fractures on the standard tessellation language (STL) file. 3D printed haptic model appears to be an efficient low-cost support for craniofacial trauma education of undergraduate students.

Published
2019

47. Response to "sleep bruxism, wake bruxism, or both? The importance of their full reporting and diagnosis".

Author

Nicot, Romain, Raoul, Gwénaël, and Sciote, James J.

Subjects
*CONSENSUS (Social sciences), *REPORT writing, *MUSCLE proteins, *INTERNATIONAL relations, *SLEEP bruxism, *MASTICATORY muscles, *CIRCADIAN rhythms, *CYTOSKELETAL proteins, *GENETIC polymorphisms, *ORAL disease diagnosis, *GENOTYPES, *WAKEFULNESS
Abstract

The article focuses on responding to the significance of accurately diagnosing bruxism based on the established criteria, exploring the ACTN3 genotype's influence on muscle characteristics concerning bruxism diagnosis. Topics include the emphasis on bruxism diagnosis following international consensus, the limitations related to including patients pre-consensus, and the clarification of ACTN3's role in influencing muscle characteristics without directly regulating bruxism's circadian rhythm.

Published
2023
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