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2 results on '"Reiko Miyahana"'

1. Impaired Coronary Flow Reserve as a Marker of Microvascular Dysfunction to Predict Long-Term Cardiovascular Outcomes, Acute Coronary Syndrome and the Development of Heart Failure

Author

Kumiko Maeda, Takahiko Kawarabayashi, Reiko Miyahana, Junichi Yoshikawa, Kenichiro Otsuka, Kenei Shimada, Hiroyuki Watanabe, Chinami Miyazaki, Minoru Yoshiyama, Shota Fukuda, and Koki Nakanishi

Subjects
Male, medicine.medical_specialty, Acute coronary syndrome, Doppler echocardiography, Coronary artery disease, Predictive Value of Tests, Risk Factors, Coronary Circulation, Internal medicine, medicine, Humans, Acute Coronary Syndrome, Risk factor, Aged, Aged, 80 and over, Heart Failure, medicine.diagnostic_test, business.industry, Microcirculation, Area under the curve, Coronary flow reserve, General Medicine, Middle Aged, medicine.disease, medicine.anatomical_structure, Echocardiography, Heart failure, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Artery
Abstract

Background: In the absence of obstructive coronary narrowing, impaired coronary flow reserve (CFR) represents coronary microvascular dysfunction. Transthoracic Doppler echocardiography (TTDE) allows non-invasive measurement of CFR in the left anterior descending (LAD) artery. This study aimed to assess the prognostic value of TTDE-derived CFR (as a marker of microvascular function) in predicting long-term cardiovascular events, acute coronary syndrome (ACS) events, and the development of heart failure (HF). Methods and Results: This study consisted of 272 patients with coronary artery disease not involving obstructive narrowing (≥50%) in the LAD. Patients underwent TTDE examination for CFR measurement in the LAD. During the follow-up period of 4.0±1.9 years, 32 patients (12%) had cardiovascular events. Cox proportional hazard analysis identified lower CFR as an independent risk factor of cardiovascular events (P

Published
2012
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2. Comparison of coronary microcirculation in female nurses after day-time versus night-time shifts

Author

Kumiko Hirata, Shota Fukuda, Yasushi Kono, Minoru Yoshiyama, Reiko Miyahana, Kenichiro Otsuka, Satoshi Jissho, Tomoichiro Kubo, Junichi Yoshikawa, Kumiko Maeda, Haruyuki Taguchi, Takashi Akasaka, Koki Nakanishi, Kenichi Komukai, and Kenei Shimada

Subjects
Adult, medicine.medical_specialty, Acute effect, Coronary microcirculation, Workload, Anterior Descending Coronary Artery, Doppler echocardiography, Coronary Angiography, Microcirculation, Japan, Risk Factors, Internal medicine, Coronary Circulation, medicine, Humans, Endothelial dysfunction, Burnout, Professional, Framingham Risk Score, medicine.diagnostic_test, business.industry, Coronary flow reserve, medicine.disease, Prognosis, Coronary Vessels, Echocardiography, Doppler, Cardiovascular Diseases, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Blood Flow Velocity, Follow-Up Studies
Abstract

Nightshift work, which is known to cause mental stress and disrupt normal biological diurnal rhythms, leads to endothelial dysfunction resulting in increased risk for cardiovascular disease. This study aimed to investigate the acute effect of night-shift work on coronary microcirculation through assessment of coronary flow reserve (CFR) by transthoracic Doppler echocardiography. This study consisted of 36 women nurses who underwent transthoracic Doppler echocardiographic examinations after working a nightshift and on a regular day without previous nightshift work. Flow velocity in the distal portion of the left anterior descending coronary artery was measured at baseline and during adenosine infusion. CFR was calculated as the ratio of hyperemic to basal mean diastolic flow velocity. CFR after night work was lower than that on a regular workday (3.8 ± 0.6 vs 4.1 ± 0.6, p

Published
2011

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