12 results on '"Robinet-Borgomano, Emmanuelle"'
Search Results
2. How Clot Composition Influences Fibrinolysis in the Acute Phase of Stroke: A Proteomic Study of Cerebral Thrombi
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Doche, Emilie, Sulowski, Constance, Guigonis, Jean-Marie, Graslin, Fanny, Casolla, Barbara, Hak, Jean-François, Carle, Xavier, Brunel, Hervé, Lindenthal, Sabine, Martin, Jean-Charles, Pourcher, Thierry, Suissa, Laurent, Alessi, Marie-Christine, Bobot, Mickael, Brinet, Abdelmalek, Dagnino, Sonia, Dehondt, Jean-Daniel, Legge, Silvia Di, Dory-Lautrec, Philippe, Dulau-Metras, Cecile, Durozard, Pierre, Kerleroux, Basile, Laksiri, Nadia, Leclercq, Barbara, Lehmann, Pierre, Magoncia, Ellen, Manzac, Christine, Osman, Ophelie, Peres, Roxane, Perez, Sandra, Rey, Caroline, Reyre, Anthony, Robinet-Borgomano, Emmanuelle, Snyman, Salome, Svilar, Ljubica, Tardivel, Catherine, Tourniaire, Patricia, and Vingadalassalom, Sivadji
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- 2024
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3. Intracranial haemorrhage in infective endocarditis
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Salaun, Erwan, Touil, Anissa, Hubert, Sandrine, Casalta, Jean-Paul, Gouriet, Frédérique, Robinet-Borgomano, Emmanuelle, Doche, Emilie, Laksiri, Nadia, Rey, Caroline, Lavoute, Cécile, Renard, Sébastien, Brunel, Hervé, Casalta, Anne-Claire, Pradier, Julie, Avierinos, Jean-François, Lepidi, Hubert, Camoin-Jau, Laurence, Riberi, Alberto, Raoult, Didier, and Habib, Gilbert
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- 2018
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4. Clinical, imaging, and management features of symptomatic carotid web: Insight from CAROWEB registry.
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Olindo, Stephane, Gaillard, Nicolas, Chausson, Nicolas, Turpinat, Cedric, Dargazanli, Cyril, Bourgeois-Beauvais, Quentin, Signate, Aissatou, Joux, Julien, Mejdoubi, Mehdi, Piotin, Michel, Obadia, Mickael, Desilles, Jean-Philippe, Delvoye, François, Holay, Quentin, Gory, Benjamin, Richard, Sébastien, Denier, Christian, Robinet-Borgomano, Emmanuelle, Carle, Xavier, and Desal, Hubert
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TRANSIENT ischemic attack ,CEREBRAL infarction ,ISCHEMIC stroke ,STROKE ,STROKE units ,SECONDARY prevention - Abstract
Background: Although carotid web (CaW) is increasingly diagnosed as a cause of cryptogenic stroke, data are still limited to monocentric small sample cohort. To broaden knowledge on symptomatic CaW, CAROWEB registry has been recently implemented. Aims: In a large cohort of symptomatic CaW patients, we described epidemiologic characteristics, admission clinical and imaging features, and the current management including the secondary preventive strategy choice made in comprehensive French Stroke Units. Methods: CAROWEB is an ongoing French observational multicenter registry enrolling consecutive CaW patients diagnosed after an ipsilateral ischemic stroke (IS) or transient ischemic attack (TIA). Submitted cases were validated by two experienced neurologist and neuroradiologist. Clinical, imaging, and management features were collected for this study. Results: Between June 2019 and December 2021, 244 cases were submitted by 14 centers, 42 rejected, and 202 included (IS, 91.6%; TIA, 7.9%; retinal infarction, 0.5%; mean age, 50.8 ± 12.2 years; female, 62.9%; Caucasian, 47.5%; Afro-Caribbean, 20.3%). IS patients showed median (interquartile range (IQR)) admission National Institutes of Health Stroke Scale (NIHSS) score, 8 (2–15); intracranial artery occlusion, 71.8%; ipsilateral chronic cerebral infarction (CCI), 16.3%; and reperfusion treatment, 57.3%. CaW was not identified during the mechanical thrombectomy procedure in 30 of 85 (35.3%) patients. Secondary prevention was invasive in 55.6% (stenting, n = 80; surgery, n = 30). In multivariable analysis, the invasive therapeutic option was associated with ipsilateral CCI (odds ratio (OR): 4.24 (1.27–14.2), p = 0.019) and inversely associated with risk factors (OR: 0.47 (0.24–0.91), p = 0.025) and admission NIHSS score (OR: 0.93 (0.89–0.97), p = 0.001). Conclusion: CaW must be considered in all ethnic groups including Caucasians. Secondary prevention is heterogeneous in large French Stroke Centers. The absence of risk factors, milder severity strokes, and ipsilateral CCI were predictive variables of secondary invasive treatment. The high rate of invasive treatment suggests that medical treatment alone is deemed ineffective to avoid recurrence and emphasize the need of randomized trials. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Clinical, Imaging and Management Features of Symptomatic Carotid Web: Insight from CAROWEB Registry
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Olindo, Stéphane, primary, Gaillard, Nicolas, additional, Chausson, Nicolas, additional, Turpinat, Cedric, additional, Dargazanli, Cyril, additional, Bourgeois-Beauvais, Quentin, additional, Signate, Aissatou, additional, Joux, Julien, additional, Mejdoubi, Mehdi, additional, Piotin, Michel, additional, Obadia, Michael, additional, Desilles, Jean-Philippe, additional, Delvoye, Francois, additional, Holay, Quentin, additional, Gory, Benjamin, additional, Richard, Sebastien, additional, Denier, Christian, additional, Robinet-Borgomano, Emmanuelle, additional, Carle, Xavier, additional, Desal, Hubert, additional, Guillon, Benoit, additional, Viguier, Alain, additional, Lamy, Matthias, additional, Pico, Fernando, additional, Landais, Anne, additional, Boulanger, Marion, additional, Renou, Pauline, additional, Gariel, Florent, additional, Papaxanthos, Jean, additional, Lhermitte, Yann, additional, Papillon, Lisa, additional, Marnat, Gaultier, additional, and Smadja, didier, additional
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- 2023
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6. Dual-layer carotid stenting for symptomatic carotid web: Results from the Caroweb study
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Marnat, Gaultier, primary, Holay, Quentin, additional, Darcourt, Jean, additional, Desilles, Jean-Philippe, additional, Obadia, Michael, additional, Viguier, Alain, additional, Caroff, Jildaz, additional, Denier, Christian, additional, Papillon, Lisa, additional, Barreau, Xavier, additional, Cognard, Christophe, additional, Berge, Jerome, additional, Bourgeois-Beauvais, Quentin, additional, Landais, Anne, additional, Boulanger, Marion, additional, Macian, Francisco, additional, Guillon, Benoit, additional, Pico, Fernando, additional, Lamy, Mathias, additional, Robinet-Borgomano, Emmanuelle, additional, Richard, Sébastien, additional, Gory, Benjamin, additional, Sibon, Igor, additional, Gaillard, Nicolas, additional, Chausson, Nicolas, additional, and Olindo, Stephane, additional
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- 2022
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7. Atrial Fibrillation Detected by Implantable Monitor in Embolic Stroke of Undetermined Source: A New Clinical Entity
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Snyman, Salomé, primary, Seder, Elena, additional, David-Muller, Marc, additional, Klein, Victor, additional, Doche, Emilie, additional, Suissa, Laurent, additional, Deharo, Jean-Claude, additional, Robinet-Borgomano, Emmanuelle, additional, and Maille, Baptiste, additional
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- 2022
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8. Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke
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Mas, Jean-Louis, Derumeaux, Geneviève, Guillon, Benoît, Massardier, Evelyne, Hosseini, Hassan, Mechtouff, Laura, Arquizan, Caroline, Béjot, Yannick, Vuillier, Fabrice, Detante, Olivier, Guidoux, Céline, Canaple, Sandrine, Vaduva, Claudia, Dequatre-Ponchelle, Nelly, Sibon, Igor, Garnier, Pierre, Ferrier, Anna, Timsit, Serge, Robinet-Borgomano, Emmanuelle, Sablot, Denis, Lacour, Jean-Christophe, Zuber, Mathieu, Favrole, Pascal, Pinel, Jean-François, Apoil, Marion, Reiner, Peggy, Lefebvre, Catherine, Guérin, Patrice, Piot, Christophe, Rossi, Roland, Dubois-Randé, Jean-Luc, Eicher, Jean-Christophe, Meneveau, Nicolas, Lusson, Jean-René, Bertrand, Bernard, Schleich, Jean-Marc, Godart, François, Thambo, Jean-Benoit, Leborgne, Laurent, Michel, Patrik, Pierard, Luc, Turc, Guillaume, Barthelet, Martine, Charles-Nelson, Anaïs, Weimar, Christian, Moulin, Thierry, Juliard, Jean-Michel, and Chatellier, Gilles
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- 2017
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9. Combined Omic Analyzes of Cerebral Thrombi: A New Molecular Approach to Identify Cardioembolic Stroke Origin
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Suissa, Laurent, primary, Guigonis, Jean-Marie, additional, Graslin, Fanny, additional, Robinet-Borgomano, Emmanuelle, additional, Chau, Yves, additional, Sedat, Jacques, additional, Lindenthal, Sabine, additional, and Pourcher, Thierry, additional
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- 2021
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10. Injectez vos AIT - Une histoire de méningite carcinomateuse
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Robinet Borgomano Emmanuelle, Snyman Salomé, Jean Pelletier, Julie Pascaud, Emilie Doche, Charline Perot, and Ophélie Osman
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Neurology ,Neurology (clinical) - Abstract
Introduction Le diagnostic d’AIT est parfois pose en l’absence d’un bilan etiologique complet. Nous rapportons les cas de 3 patients adresses pour suspicion d’evenements cerebro-vasculaires revelant une meningite carcinomateuse. Observation Cas 1 : Un patient de 70 ans suivi pour un adenocarcinome prostatique a consulte pour un trouble elocutoire de trois minutes brutal a IRM normale etiquete AIT. Il a presente un episode similaire un an plus tard durant quelques secondes. L’IRM a montre une pachymeningite, deja presente sur la premiere IRM apres relecture. Deux ponctions lombaires (PL) retrouvaient une hyperproteinorachie > 1,5 g/L en l’absence de meningite ou cellule atypique. Cas 2 : Une patiente de 72 ans, traitee pour un adenocarcinome mammaire, a ete prise en charge en phase aigue pour trouble elocutoire brutal, hemiparesie droite, vertiges. Les sequences classiques d’AVC etaient normales. L’injection a montre une prise de contraste meningee cerebelleuse. Les PL ont retrouve une hyperproteinorachie > 3 g/L et des cellules carcinomateuses. Cas 3 : Une patiente de 70 ans, sans antecedent, a consulte pour des troubles elocutoires de quelques secondes etiquetes AIT devant un scanner injecte normal. Un episode similaire revele une prise de contraste meningee a l’IRM. La PL a retrouve une meningite et des cellules carcinomateuses. Le bilan a identifie un adenocarcinome bronchique. Discussion Ces cas montrent que des deficits neurologiques transitoires peuvent reveler des meningites carcinomateuses, y compris chez des patients sans antecedent neoplasique connu. La meningite carcinomateuse est une complication rare mais grave des tumeurs solides et hemopathies malignes. Son heterogeneite clinico-radiologique rend son diagnostic difficile et souvent retarde. La normalite de l’IRM justifie une injection de gadolinium et une ponction lombaire. Conclusion Le diagnostic d’AIT ne doit pas etre pose devant tout deficit neurologique transitoire a imagerie normale sans la realisation d’un bilan comprenant une IRM injectee et eventuellement une ponction lombaire.
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- 2020
11. Angiopathie amyloide cérébrale chez des sujets jeunes à distance d’une intervention neurochirurgicale : à propos de 4 cas
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Robinet Borgomano Emmanuelle, Nadia Laksiri, Jean Pelletier, Ophélie Osman, Bérengère Ruel, Caroline Rey, and Emilie Doche
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Neurology ,Neurology (clinical) - Abstract
Introduction Des cas d’angiopathie amyloide cerebrale (AAC) precoce ont recemment ete rapportes chez des patients a distance d’une intervention neurochirurgicale. Nous rapportons 4 cas suivis a l’UNV du CHU de Marseille. Observation Cas 1. Une patiente de 42 ans a presente un hematome lobaire spontane, 40 ans apres une chirurgie d’une lesion du quatrieme ventricule. L’IRM a montre des stigmates evocateurs d’AAC et l’evolution a ete marquee par une majoration des lesions radiologiques et l’apparition de troubles cognitifs. Cas 2. Une patiente de 53 ans a presente un infarctus sylvien punctiforme, a 34 ans d’une chirurgie d’hemorragie cerebelleuse. Elle a presente ensuite plusieurs hemorragies cerebrales et l’accumulation de microsaignements a l’IRM. Cas 3. Une patiente de 53 ans a presente une hemorragie sous arachnoidienne (HSA) et un hematome lobaire spontane, 21 ans apres la chirurgie d’une lesion cerebelleuse. L’IRM retrouvait des stigmates de microangiopathie et le suivi a montre une recidive d’hemorragie cerebrale precoce. Cas 4. Un patient de 39 ans a presente une HSA focale, a 37 ans d’une chirurgie d’une malformation arterioveineuse cerebrale. Il existait une leucopathie et des microsaignements qui se sont progressivement majores sur les IRMs de suivi. Chez ces 4 patients, le bilan extensif etait negatif. Aucune mutation impliquee dans les formes genetiques d’AAC n’a ete identifiee. Discussion Nous decrivons 4 patients qui ont presente un tableau d’AAC avant 55 ans, avec un antecedent neurochirurgical parfois tres lointain et un bilan complet negatif. Ceci fait suspecter une AAC “iatrogene”, avec un mecanisme suppose ‘prion-like’, comme exceptionnellement rapporte dans la litterature. Une biopsie cerebrale montrant des depots de proteine Ab dans la paroi vasculaire conforterait notre hypothese. Conclusion De rares cas d’AAC du sujet jeune, sans mutation et aux antecedents neurochirurgicaux ont recemment fait evoquer un mecanisme iatrogene. L’identification de nouveaux cas permettrait d’en preciser le profil clinico-radiologique.
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- 2020
12. Dual-layer carotid stenting for symptomatic carotid web: Results from the Caroweb study.
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Marnat G, Holay Q, Darcourt J, Desilles JP, Obadia M, Viguier A, Caroff J, Denier C, Papillon L, Barreau X, Cognard C, Berge J, Bourgeois-Beauvais Q, Landais A, Boulanger M, Macian F, Guillon B, Pico F, Lamy M, Robinet-Borgomano E, Richard S, Gory B, Sibon I, Gaillard N, Chausson N, and Olindo S
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- Humans, Middle Aged, Retrospective Studies, Fibrinolytic Agents, Treatment Outcome, Stents adverse effects, Risk Factors, Carotid Stenosis diagnostic imaging, Carotid Stenosis surgery, Stroke etiology, Stroke prevention & control, Stroke surgery, Endarterectomy, Carotid adverse effects, Endarterectomy, Carotid methods
- Abstract
Background & Purpose: Carotid Web (CaW) is a growingly recognized cause of ischemic stroke, associated with a high recurrence risk. Several therapeutic strategies have been proposed as a tertiary prevention including carotid stenting, endarterectomy and antithrombotic medications. Among these, carotid stenting with dual-layer stent may be promising to adequately cover the focal arterial dysplasia. Our aim was to investigate the safety and efficacy of the Casper stent in the treatment of symptomatic CaW., Methods: We conducted a retrospective analysis of consecutive patients presenting with a symptomatic CaW and included in the ongoing prospective observational multicenter CAROWEB registry. The study period was January 2015 to December 2021. Inclusion criteria were CaW treated with dual-layer Casper stent. Patients treated with other types of carotid stent, endarterectomy or antithrombotic medication were excluded. Clinical and radiological initial data and outcomes were recorded., Results: twenty-seven patients (with 28 caw) were included. median age was 52 (iqr: 46-68). median delay between index cerebrovascular event and cervical stenting was 9 days (IQR: 6-101). In all cases, the cervical carotid stenting was successfully performed. No major perioperative complication was recorded. No recurrent stroke or transient ischemic attack was observed during a median follow-up time of 272 days (IQR: 114-635). Long-term imaging follow-up was available in 25/28 (89.3%) stented CaW with a median imaging follow-up of 183 days (IQR: 107-676; range: 90-1542). No in-stent occlusion or stenosis was detected., Conclusion: In this study, carotid stenting with dual-layer Casper stent in the treatment of symptomatic CaW was effective regarding stroke recurrence prevention and safe, without procedural nor delayed detected adverse event. However, the optimal therapeutic approach of symptomatic CaW still needs to be explored through randomized trials., (Copyright © 2022 Elsevier Masson SAS. All rights reserved.)
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- 2023
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