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254 results on '"Ryan, Edwin H."'

1. A Comparative Study of Responses to Retina Questions from Either Experts, Expert-Edited Large Language Models, or Expert-Edited Large Language Models Alone

Author

Tailor, Prashant D., Dalvin, Lauren A., Chen, John J., Iezzi, Raymond, Olsen, Timothy W., Scruggs, Brittni A., Barkmeier, Andrew J., Bakri, Sophie J., Ryan, Edwin H., Tang, Peter H., Parke, D. Wilkin., III, Belin, Peter J., Sridhar, Jayanth, Xu, David, Kuriyan, Ajay E., Yonekawa, Yoshihiro, and Starr, Matthew R.

Published
2024
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10. SPONTANEOUS IMPROVEMENT OF MYOPIC RETINOSCHISIS AFTER A LONG-TERM OBSERVATIONAL PERIOD: A CASE SERIES.

Author

Hussein, Musse, Adeleye, Olufunmilola, Adams, Olufemi E., Sodhi, Guneet S., Haq, Zeeshan, Quiram, Polly A., Tang, Peter H., and Ryan, Edwin H.

Abstract

Purpose: To highlight spontaneous resolution or improvement of myopic retinoschisis (MR) in actively surveilled patients. Methods: Case series of five patients diagnosed with MR who did not undergo pars plana vitrectomy and were carefully monitored by a single retina specialist. Ocular and medical history were reviewed, and clinical characteristics including visual acuity and the status of the MR were monitored with spectral domain optical coherence tomography (SDOCT) at each clinic visit. Results: Five patients were identified to have MR without vitreomacular traction, or macular hole formation. Two patients exhibited spontaneous and complete resolution of MR without surgical intervention over an average observation time of 52.5 months. In these cases, a clinical posterior vitreous detachment was documented preceding the resolution of MR over an average time of 26.5 months. Snellen best-corrected visual acuity in these patients improved (Case 1 from 20/50 to 20/40, Case 2 from 20/30 to 20/25). The remaining three patients were monitored for an average of 52 months and showed improvement of MR via OCT imaging. Snellen best-corrected visual acuity either remained stable or improved from baseline (Case 3 stable at 20/30, Case 4 improved from 20/40 to 20/30, and Case 5 stable at 20/20). Conclusion: These findings suggest that conservative management of MR with observation can be considered especially in patients with challenging comorbidities (such as monocular status), and with a clinically identified posterior vitreous detachment without vitreomacular traction. [ABSTRACT FROM AUTHOR]

Published
2024
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11. A Comparative Study of Responses to Retina Questions from either Experts, Expert-Edited Large Language Models (LLMs) or LLMs Alone

Author

Tailor, Prashant D., primary, Dalvin, Lauren A., additional, Chen, John J., additional, Iezzi, Raymond, additional, Olsen, Timothy W., additional, Scruggs, Brittni A., additional, Barkmeier, Andrew J., additional, Bakri, Sophie J., additional, Ryan, Edwin H., additional, Tang, Peter H., additional, Parke, D. Wilkin., additional, Belin, Peter J., additional, Sridhar, Jayanth, additional, Xu, David, additional, Kuriyan, Ajay E., additional, Yonekawa, Yoshihiro, additional, and Starr, Matthew R., additional

Published
2024
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12. Geographic Atrophy Management Consensus (GA-MAC): a Delphi panel study on identification, diagnosis and treatment

Author

Kaiser, Peter K, primary, Karpecki, Paul M, additional, Regillo, Carl D, additional, Baumal, Caroline, additional, Ryan, Edwin H, additional, Ip, Michael S, additional, Modi, Yasha, additional, Yeu, Elizabeth, additional, Nijm, Lisa, additional, Farid, Marjan, additional, Rebenitsch, Ronald Luke, additional, Kim, Terry, additional, Shechtman, Diana L, additional, Nichols, Kelly, additional, Schweitzer, Justin, additional, Dunbar, Mark T, additional, Rafieetary, Mohammad R, additional, and Donnenfeld, Eric D, additional

Published
2023
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15. Prophylactic treatment of lattice degeneration in fellow eyes after repair of uncomplicated primary rhegmatogenous retinal detachment

Author

Curran, Christian D., primary, Adams, Olufemi E., additional, Vagaggini, Tommaso, additional, Sodhi, Guneet S., additional, Prairie, Michael L., additional, Baker, Mikayla J., additional, Sastry, Ananth, additional, Ryan, Edwin H., additional, Parke 3r d, D. Wilkin., additional, Mittra, Robert A., additional, Dev, Sundeep, additional, and Tang, Peter H., additional

Published
2023
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18. Considerations for the Identification and Management of Geographic Atrophy: Recommendations from an Expert Panel.

Author

Regillo, Carl D, Nijm, Lisa M, Shechtman, Diana L, Kaiser, Peter K, Karpecki, Paul M, Ryan, Edwin H, Ip, Michael S, Yeu, Elizabeth, Kim, Terry, Rafieetary, Mohammad R, and Donnenfeld, Eric D

Subjects
MACULAR degeneration, ATROPHY, EYE care
Abstract

Newly approved treatments for patients with geographic atrophy are changing the treatment paradigm, highlighting the need for eye care providers (ECPs) to have a set of recommendations on how to best manage GA patients. Here, we outline how to identify various stages of age-related macular degeneration including geographic atrophy (GA) by examining optimal management scenarios implicating various ECPs and reviewing treatment considerations for patients with GA. Early identification of GA will lead to optimal patient outcomes, while a standardized management scenario will reduce clinical burden among ECPs treating patients with GA. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Scleral Buckling for Primary Retinal Detachment: Outcomes of Scleral Tunnels versus Scleral Sutures

Author

Starr, Matthew R., Ryan, Edwin H., Obeid, Anthony, Ryan, Claire, Gao, Xinxiao, Madhava, Malika L., Maloney, Sean M., Adika, Adam Z., Peddada, Krishi V., Sioufi, Kareem, Patel, Luv G., Ammar, Michael J., Forbes, Nora J., Capone Jr., Antonio, Emerson, Geoffrey G., Joseph, Daniel P., Eliott, Dean, Regillo, Carl D., Hsu, Jason, Gupta, Omesh P., Yonekawa, Yoshihiro, and Study Group, for the Primary Retinal Detachment Outcomes (PRO)

Subjects
medicine.medical_specialty, Visual acuity, genetic structures, medicine.medical_treatment, Vitrectomy, Scleral buckle, Scleral Suture, Suture (anatomy), Scleral Buckle, Ophthalmology, medicine, Strabismus, Rhegmatogenous Retinal Detachment, business.industry, Retinal detachment, Retrospective cohort study, RE1-994, medicine.disease, eye diseases, Sclera, Scleral Tunnels, medicine.anatomical_structure, Original Article, sense organs, medicine.symptom, business
Abstract

Purpose: There are primarily two techniques for affixing the scleral buckle (SB) to the sclera in the repair of rhegmatogenous retinal detachment (RRD): scleral tunnels or scleral sutures. Methods: This retrospective study examined all patients with primary RRD who were treated with primary SB or SB combined with vitrectomy from January 1, 2015 through December 31, 2015 across six sites. Two cohorts were examined: SB affixed using scleral sutures versus scleral tunnels. Pre- and postoperative variables were evaluated including visual acuity, anatomic success, and postoperative strabismus. Results: The mean preoperative logMAR VA for the belt loop cohort was 1.05 ± 1.06 (Snellen 20/224) and for the scleral suture cohort was 1.03 ± 1.04 (Snellen 20/214, p = 0.846). The respective mean postoperative logMAR VAs were 0.45 ± 0.55 (Snellen 20/56) and 0.46 ± 0.59 (Snellen 20/58, p = 0.574). The single surgery success rate for the tunnel cohort was 87.3% versus 88.6% for the suture cohort (p = 0.601). Three patients (1.0%) in the scleral tunnel cohort developed postoperative strabismus, but only one patient (0.1%) in the suture cohort (p = 0.04, multivariate p = 0.76). All cases of strabismus occurred in eyes that underwent SB combined with PPV (p = 0.02). There were no differences in vision, anatomic success, or strabismus between scleral tunnels versus scleral sutures in eyes that underwent primary SB. Conclusion: Scleral tunnels and scleral sutures had similar postoperative outcomes. Combined PPV/SB in eyes with scleral tunnels might be a risk for strabismus post retinal detachment surgery.

Published
2021

27. Hemi- and Central Retinal Vein Occlusion Associated with COVID-19 Infection in Young Patients without Known Risk Factors

Author

Ashkenazy, Noy, primary, Patel, Nimesh A., additional, Sridhar, Jayanth, additional, Yannuzzi, Nicolas A., additional, Belin, Peter J., additional, Kaplan, Richard, additional, Kothari, Nikisha, additional, Benitez Bajandas, Gabriel A., additional, Kohly, Radha P., additional, Roizenblatt, Roberto, additional, Pinhas, Alexander, additional, Mundae, Rusdeep, additional, Rosen, Richard B., additional, Ryan, Edwin H., additional, Chiang, Allen, additional, Chang, Louis K., additional, Khurana, Rahul N., additional, and Finn, Avni P., additional

Published
2022
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28. PRO score: predictive scoring system for visual outcomes after rhegmatogenous retinal detachment repair.

Author

Cai, Louis Z., Lin, Jeffrey, Starr, Matthew R., Obeid, Anthony, Ryan, Edwin H., Ryan, Claire, Forbes, Nora J., Arias, Diego, Ammar, Michael J., Patel, Luv G., Capone, Antonio, Emerson, Geoffrey Guy, Joseph, Daniel P., Eliott, Dean, Gupta, Omesh P., Regillo, Carl D., Hsu, Jason, and Yoshihiro Yonekawa

Abstract

Background/aims To compare risk factors for poor visual outcomes in patients undergoing primary rhegmatogenous retinal detachment (RRD) repair and to develop a scoring system. Methods Analysis of the Primary Retinal detachment Outcomes (PRO) study, a multicentre interventional cohort of consecutive primary RRD surgeries performed in 2015. The main outcome measure was a poor visual outcome (Snellen VA ≤20/200). Results A total of 1178 cases were included. The mean preoperative and postoperative logMARs were 1.1±1.1 (20/250) and 0.5±0.7 (20/63), respectively. Multivariable logistic regression identified preoperative risk factors predictive of poor visual outcomes (≤20/200), including proliferative vitreoretinopathy (PVR) (OR 1.26; 95% CI 1.13 to 1.40), history of antivascular endothelial growth factor (VEGF) injections (1.38; 1.11 to 1.71), >1-week vision loss (1.17; 1.08 to 1.27), ocular comorbidities (1.18; 1.00 to 1.38), poor presenting VA (1.06 per initial logMAR unit; 1.02 to 1.10) and age >70 (1.13; 1.04 to 1.23). The data were split into training (75%) and validation (25%) and a scoring system was developed and validated. The risk for poor visual outcomes was 8% with a total score of 0, 17% with 1, 29% with 2, 47% with 3, and 71% with 4 or higher. Conclusions Independent risk factors were compared for poor visual outcomes after RRD surgery, which included PVR, anti-VEGF injections, vision loss >1 week, ocular comorbidities, presenting VA and older age. The PRO score was developed to provide a scoring system that may be useful in clinical practice. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Reply

Author

Wagley, Sushant, primary and Ryan, Edwin H., additional

Published
2022
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33. Involution of Neovascular Age-Related Macular Degeneration Following Endophthalmitis

Author

Kokame, Gregg T., Yannuzzi, Nicolas A., Shantha, Jessica G., Yamane, Maya, Relhan, Nidhi, Gross, Jeffrey, Ryan, Edwin H., and Flynn, Harry W.

Subjects
genetic structures, sense organs, eye diseases, Article
Abstract

PURPOSE: To report patients who demonstrated an alteration in the clinical and optical coherence tomography (OCT) features of neovascular age-related macular degeneration (AMD) following resolution of endophthalmitis. METHODS: Retrospective case series of the subsequent changes in the macula and need for anti-VEGF therapy in patients with neovascular AMD who developed endophthalmitis following intravitreal injection. RESULTS: The study included 7 eyes of 7 patients with follow-up ranging between 3 months and 11 years. The vitreous cultures (n=7) prior to intravitreal antibiotic injection were the following: culture negative (4) and coagulase-negative Staphylococcus (3). Initial treatment included vitreous tap and injection (4) and pars plana vitrectomy (PPV, 3). In 5/7 eyes, the OCT showed resolution of subretinal fluid and serous pigment epithelial detachment and there was no additional anti-VEGF treatment administered. CONCLUSION: After successful treatment of endophthalmitis in patients with neovascular AMD, there was relative involution of the maculopathy and reduced anti-VEGF treatment burden in this series.

Published
2021

35. PRO score: predictive scoring system for visual outcomes after rhegmatogenous retinal detachment repair

Author

Cai, Louis Z, primary, Lin, Jeffrey, additional, Starr, Matthew R, additional, Obeid, Anthony, additional, Ryan, Edwin H, additional, Ryan, Claire, additional, Forbes, Nora J, additional, Arias, Diego, additional, Ammar, Michael J, additional, Patel, Luv G, additional, Capone, Antonio, additional, Emerson, Geoffrey Guy, additional, Joseph, Daniel P, additional, Eliott, Dean, additional, Gupta, Omesh P, additional, Regillo, Carl D, additional, Hsu, Jason, additional, and Yonekawa, Yoshihiro, additional

Published
2021
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40. Closure of Full-Thickness Macular Holes Associated with Macular Edema with Medical Therapy

Author

Kokame, Gregg T., primary, Johnson, Mark W., additional, Lim, Jennifer, additional, Flynn Jr., Harry W., additional, de Carlo, Talisa E., additional, Yannuzzi, Nicolas A., additional, Ryan, Edwin H., additional, Omizo, Jase N., additional, Sridhar, Jayanth, additional, Staropoli, Patrick, additional, Goldhagen, Brian, additional, and Lian, Rebecca, additional

Published
2021
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42. Ranibizumab combined with low-dose sorafenib for exudative age-related macular degeneration

Author

Diago, Teresa, Pulido, Joes S., Molina, Julian R., Collet, Lucienne C., Link, Thomas P., and Ryan, Edwin H., Jr.

Subjects
Macular degeneration -- Care and treatment, Neovascularization -- Prevention, Drug therapy, Combination -- Research
Abstract

Angiogenesis is a common factor in the pathogenesis of cancer and in exudative age-related macular degeneration (AMD). Therefore, angiogenesis inhibition has been developed as a therapeutic strategy. We report 2 [...]

Published
2008

46. Closure of Full-Thickness Macular Holes Associated with Macular Edema with Medical Therapy.

Author

Kokame, Gregg T., Johnson, Mark W., Lim, Jennifer, Flynn, Harry W., de Carlo, Talisa, Yannuzzi, Nicolas, Ryan, Edwin H., Omizo, Jase N., Sridhar, Jayanth, Staropoli, Patrick, Goldhagen, Brian, and Lian, Rebecca

Subjects
MACULAR edema, CARBONIC anhydrase inhibitors, DIABETIC retinopathy
Abstract

Purpose: The purpose of this study was to report the closure of macular hole without surgery in 7 cases using medical therapies. Methods: The retrospective review of 7 cases of full-thickness macular holes, which closed after medical therapy without surgery. Results: Seven eyes of 7 patients developed full-thickness macular holes, which initially closed on medical therapy without surgery. Six patients were kept on maintenance therapy; 1 recurred and 5 did not develop recurrence. One patient was taken off of maintenance therapy and later developed recurrent macular hole requiring macular hole surgery. Conclusions: Medical therapy to decrease macular edema may facilitate macular hole closure and should be considered, especially for small macular holes with significant edema. Reopening of macular holes may occur after stopping topical maintenance therapy for macular edema, which occurred at 10 weeks and 9 months after maintenance therapy was discontinued or markedly tapered. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Primary Retinal Detachment Outcomes Study: Pseudophakic Retinal Detachment Outcomes

Author

Joseph, Daniel P., primary, Ryan, Edwin H., additional, Ryan, Claire M., additional, Forbes, Nora J.K., additional, Wagley, Sushant, additional, Yonekawa, Yoshihiro, additional, Mittra, Robert A., additional, Parke, D. Wilkin, additional, Emerson, Geoffrey G., additional, Shah, Gaurav K., additional, Blinder, Kevin J., additional, Capone, Antonio, additional, Williams, George A., additional, Eliott, Dean, additional, Gupta, Omesh P., additional, Hsu, Jason, additional, and Regillo, Carl D., additional

Published
2020
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49. Posterior Retinotomy vs Perfluorocarbon Liquid to Aid Drainage of Subretinal Fluid During Primary Rhegmatogenous Retinal Detachment Repair (PRO Study Report No. 10)

Author

Vo, Loi V., primary, Ryan, Edwin H., additional, Ryan, Claire M., additional, Shah, Gaurav K., additional, Gupta, Omesh P., additional, Capone, Antonio, additional, Eliott, Dean, additional, Yonekawa, Yoshihiro, additional, Bhavsar, Abdhish R., additional, Emerson, M. Vaughn, additional, Jones, Jacob M., additional, and Emerson, Geoffrey G., additional

Published
2020
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50. Primary Retinal Detachment Outcomes Study: Methodology and Overall Outcomes—Primary Retinal Detachment Outcomes Study Report Number 1

Author

Ryan, Edwin H., primary, Joseph, Daniel P., additional, Ryan, Claire M., additional, Forbes, Nora J.K., additional, Yonekawa, Yoshihiro, additional, Mittra, Robert A., additional, Parke, D. Wilkin, additional, Ringeisen, Alex, additional, Emerson, Geoffrey G., additional, Shah, Gaurav K., additional, Blinder, Kevin J., additional, Capone, Antonio, additional, Williams, George A., additional, Eliott, Dean, additional, Gupta, Omesh P., additional, Hsu, Jason, additional, and Regillo, Carl D., additional

Published
2020
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