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3. Late auditory event-related potential changes after sensorimotor rhythm neurofeedback training

Author

Stanković Ivana, Ilić Tihomir V., Jeličić Ljiljana, Subotić Miško, Martić Vesna, Sovilj Mirjana, Ilić Nela V., and Stokić Miodrag

Subjects
brain, cognition, electroencephalography, event-related potentials, p300, evoked potentials, evoked potentials, auditory, feedback, sensory, Medicine (General), R5-920
Abstract

Background/Aim. Neurofeedback (NFB) is a therapeutic method based on monitoring the electroencephalogram (EEG) and providing feedback on the brain activity of sub-jects. The aim of the pilot study was to investigate the effect of lower-beta or sensorimotor rhythm (SMR) (12–15 Hz) NFB training on amplitudes and latencies of late auditory event-related potentials (aERP) components N100, N200, P300 in Go-No go task of auditory discrimination. Methods. Each of 9 healthy participants aged 25–40 years (4 male) had 20 daily sessions of SMR neurofeedback training. The aERP was recorded 5 times: before NFB, after 5, 10, and 20 sessions, and one m onth after the last session. Results. The results showed a statistically significant decrease in N100, N200, and P300 latencies at Fz, Cz, and Pz regions. No significant effect of NFB training on amplitudes of components N100, N200 and N300 was found. Conclusion. The obtained results suggest that NFB training exerts its effect on the processes of auditory cognition.

Published
2022
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6. Speech-language pathologists' professional stress level and factors affecting it in the Republic of Serbia.

Author

Milanović, Ivana, Stanojević, Nina, Fatić, Saška, Marisavljević, Maša, Punišić, Silvana, Janjić, Vladimir, Subotić, Miško, and Maksimović, Slavica

Subjects
SPEECH therapists, WORK, STATISTICAL power analysis, SCALE analysis (Psychology), PSYCHOLOGICAL burnout, MENTAL health, CRONBACH'S alpha, T-test (Statistics), DATA analysis, RESEARCH funding, PUBLIC sector, QUESTIONNAIRES, AGE distribution, SEVERITY of illness index, DESCRIPTIVE statistics, PRIVATE sector, MANN Whitney U Test, JOB stress, MARITAL status, ONE-way analysis of variance, STATISTICS, SOCIODEMOGRAPHIC factors, QUALITY assurance, FACTOR analysis, DATA analysis software, PSYCHOSOCIAL factors, EMPLOYEES' workload, EXPERIENTIAL learning, EDUCATIONAL attainment
Abstract

BACKGROUND: In the Republic of Serbia, to our knowledge, there has been no research dedicated to the professional stress faced by speech-language pathologists (SLPs). Since speech therapy belongs to the helping professions, SLPs might experience professional stress. OBJECTIVE: To examine the levels of professional stress in SLPs concerning sociodemographic characteristics and terms of the workplace. METHODS: The research was conducted online, using a questionnaire designed to determine professional stress in speech-language pathologists - Speech-Language Pathologist Stress Inventory. The voluntary sample consisted of 185 employed SLPs from the Republic of Serbia. The stress level was observed concerning marital status, years of working experience, age, educational degree, caseload size, job sector, job setting, type of patients' diagnosis, and type of service which SLPs provide. RESULTS: The results showed that SLPs experience mild to moderate levels of professional stress and that there is a statistically significant difference in the stress level concerning years of working experience, age, job sector, and job setting. Applying Generalized Linear Mixed Model revealed that two-way interaction (Years of working experience * Marital status) and three-way interaction (Age * Job Setting * Type of patients' diagnosis) dominated on the model. CONCLUSION: Since it is noted that SLPs are experiencing mild to moderate levels of professional stress, it is important to emphasize the need for adaptation of existing work terms as well as to provide additional support to speech therapists in order to improve their mental health. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Arterial Presumed Perinatal Ischemic Stroke: A Mini Review and Case Report of Cognitive and Speech-Language Profiles in a 5-Year-Old Girl.

Author

Bogavac, Ivana, Jeličić, Ljiljana, Marisavljević, Maša, Bošković Matić, Tatjana, and Subotić, Miško

Subjects
BRAIN damage complications, CEREBRAL hemispheres, NEUROBIOLOGY, SPEECH therapy, ISCHEMIC stroke, COGNITION in children, FUNCTIONAL status, CHILD development, LANGUAGE & languages, NEUROPLASTICITY, SPEECH evaluation, LANGUAGE acquisition, PATIENT monitoring, TREATMENT effectiveness, CHILD psychopathology, EARLY intervention (Education), PERINATAL period, SPEECH, NEURORADIOLOGY, DISEASE risk factors, DISEASE complications, SYMPTOMS, CHILDREN
Abstract

Arterial presumed perinatal ischemic stroke is a type of perinatal stroke that emerges due to late or delayed diagnostics of perinatal or neonatal arterial ischemic stroke. It is usually recognized before one year of life due to hemiparesis. This injury may lead to cognitive, behavioral, or motor symptoms, and life-long neurodevelopmental disabilities. In this case report, we describe a five-year-old girl with a history of arterial presumed perinatal ischemic stroke in the left hemisphere, which adversely affected her cognitive and language outcomes. The girl's cognitive development has been uneven, ranging from below average to average, and she had specific language acquisition deficits in comprehension, vocabulary, morphology, use of complex syntax, and narrative structure. The obtained results point to the specificity of each child whose development is influenced not only by the timing of the brain lesion and the degree of damage, but also by the child's neurobiological capacity. In addition, we provide an updated review of the literature that includes information on epidemiology, risk factors, diagnostics, clinical manifestations, outcomes, and potential therapies. The present article highlights the importance of early intervention and systematic monitoring of children with perinatal stroke with the aim of improving the child's development. [ABSTRACT FROM AUTHOR]

Published
2024
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19. The changes in relation of auditory and visual input activity between hemispheres analized in cartographic EEG in a child with hyperactivity syndrome

Author

Radičević Zoran, Jeučić Ljiljana, Bogavac Ivana, Stokić Miodrag, Sovilj Mirjana, and Subotić Miško

Subjects
cartographic EEG, attention disorder, auditory and visual information processing, Neurofeedback treatment, Special aspects of education, LC8-6691
Abstract

The paper discusses the changes in relations of visual and auditory inputs between the hemispheres in a child with hyperactive syndrome and its effects which may lead to better attention engagement in auditory and visual information analysis. The method included the use of cartographic EEG and clinical procedure in a 10-year-old boy with hyperactive syndrome and attention deficit disorder, who has theta dysfunction manifested in standard EEG. Cartographic EEG patterns was performed on NihonKohden Corporation, EEG - 1200K Neurofax apparatus in longitudinal bipolar electrode assembly schedule by utilizing10/20 International electrode positioning. Impedance was maintained below 5 kΩ, with not more than 1 kΩ differences between the electrodes. Lower filter was set at 0.53 Hz and higher filter at 35 Hz. Recording was performed in a quiet period and during stimulation procedures that include speech and language basis. Standard EEG and Neurofeedback (NFB) treatment indicated higher theta load, alpha 2 and beta 1 activity measured in the cartographic EEG which was done after the relative failure of NFB treatment. After this, the NFB treatment was applied which lasted for six months, in a way that when the boy was reading, the visual input was enhanced to the left hemisphere and auditory input was reduced to the right hemisphere. Repeated EEG mapping analysis showed that there was a significant improvement, both in EEG findings as well as in attention, behavioural and learning disorders. The paper discusses some aspects of learning, attention and behaviour in relation to changes in the standard EEG, especially in cartographic EEG and NFB findings.

Published
2015
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26. Neuroinflammation in Autism and Supplementation Based on Omega-3 Polyunsaturated Fatty Acids: A Narrative Review

Author

Veselinović, Aleksandra, Veselinović, Aleksandra, Petrović, Snježana, Žikić, Vladica, Subotić, Miško, Jakovljević, Vladimir, Jeremić, Nevena, Vučić, Vesna M., Veselinović, Aleksandra, Veselinović, Aleksandra, Petrović, Snježana, Žikić, Vladica, Subotić, Miško, Jakovljević, Vladimir, Jeremić, Nevena, and Vučić, Vesna M.

Abstract

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts and restricted, repetitive patterns of behavior, interests and activities. The maternal status of polyunsaturated fatty acids (PUFA) regulates microglial activity and neuroinflammatory pathways during a child’s brain development. In children with ASD, the metabolism of PUFA is thought to be deficient or abnormal, leading to increased production of proinflammatory cytokines, increased oxidative stress and an imbalance in the formation and action of neurotransmitters. In addition, nutritional deficits in omega-3 PUFA may affect gut microbiota and contribute to ASD by the gut–brain axis. The aim of this study was to review the possible role of neuroinflammation in ASD development and the effect of omega-3 PUFA supplementation in children with ASD. Due to a wide heterogeneity across RCTs, no definitive conclusion about omega-3 PUFA effects in ASD can be drawn. Supplementation with PUFA could be considered as one of the aspects in regulating the biological status of the organism and could provide added value to standard medical and psychological interventions for reducing behavioral deficits.

Published
2021

28. The speech and language profile of a child with Turner Syndrome– a case study.

Author

Bogavac, Ivana, Jeličić, Ljiljana, Nenadović, Vanja, Subotić, Miško, and Janjić, Vladimir

Subjects
PHYSIOLOGICAL aspects of speech, SPEECH disorders, LINGUISTICS, SPEECH evaluation, LANGUAGE acquisition, CASE studies, RESEARCH funding, TURNER'S syndrome, COGNITIVE testing, LANGUAGE disorders, LONGITUDINAL method, INTELLIGENCE tests, MOTOR ability, DISEASE complications
Abstract

Turner syndrome is a genetic disorder that affects only females. It has specific cognitive characteristics, but speech and language data are scarce. Prospective case report; we report a girl aged seven's cognitive and speech and language profile. Cognitive assessment shows higher performance IQ (PIQ), and atypical cognitive profile for Turner syndrome. Speech and language assessment show a significant difference between receptive and expressive language levels. Although the girl did comprehend most of the language structure, there was a lack of it in spontaneous speech. She demonstrated inconsistency in the use of language morphology and complex linguistic structures, primarily because of significant inconsistency in her sound production. Although she produced the majority of phonemes correctly in isolation, her spontaneous speech production was incomprehensible. Case studies of speech and language development may reveal a specific characteristic in the cases with Turner syndrome to delineate genetic factors from individual developmental variabilities. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Head righting reflex in newborns as the predictive factor of early child development: a longitudinal study.

Author

Adamović, Tatjana, Jurišić-Škevin, Aleksandra, Madić, Dejan, Sovilj, Mirjana, Jeličić, Ljiljana, Maksimović, Slavica, and Subotić, Miško

Subjects
NEWBORN infants, LANGUAGE acquisition, LONGITUDINAL method, SOCIAL emotional learning, EMOTION regulation
Abstract

This study analysed whether the assessment of head righting reflex (HRR) in babies immediately after birth can be used in prediction of early child development. In 54 healthy newborns, testing of HRR was conducted on the third day upon birth. The HRR at birth were correlated with balance ability (BA), speech and language development (SLD) and social-emotional behaviour (SEB), on the same sample of children at the age of 5. Children whose HRR was absent or incomplete immediately after birth, later start to sit, stand, walk and talk and that differences are statistically significant (p<0.02, p<0.05, p<0.01 and p<0.01 respectively). Children with better BA (t = 2,32; p<0.02) and SLD (t = 2,33; p<0.02) at the age of 5, had present HRR at birth. Although the HRR reaches its full maturity at the end of the 2nd month of life, its onset immediately after birth could serve as a predictor of early child development. [ABSTRACT FROM AUTHOR]

Published
2022
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32. Анализа обележја у говорном сигналу за потребе препознавања мултимодалног говора

Author

Mijić, Miomir, Šumarac-Pavlović, Dragana, Subotić, Miško, Marković, Branko R., Mijić, Miomir, Šumarac-Pavlović, Dragana, Subotić, Miško, and Marković, Branko R.

Abstract

У системима аутоматског препознавња говора све значајнију улогу игра и мултимодални говор..., In automatic speech recognition systems, multimodal speech is playing an increasingly important role. Different modes of speech involve different acoustic features. Particular importance is given to normal (natural) speech, whisper and their combinations (when the system is trained by normal speech and then used to recognize whisper, and vice versa). The match scenarios: „normal/normal“ and „whisper/whisper“, and mismatch scenarios: „normal/whisper“ and „whisper/normal“ are considered here...

Published
2018

33. Ocena kvaliteta artikulacije glasova srpskog jezika primenom neuronskih mreža

Author

Stanković, Srđan, Đurović, Željko, Šarić, Zoran, Tomašević, Milo, Subotić, Miško, Furundžić, Draško V., Stanković, Srđan, Đurović, Željko, Šarić, Zoran, Tomašević, Milo, Subotić, Miško, and Furundžić, Draško V.

Abstract

Glavni zadatak istraživanja prikazanog u disertaciji je modeliranje složenog procesa logopedske procene kvaliteta artikulacije fonema srpskog jezika, zasnovane na inteligentnim „data driven“ učećim modelima. Multidisciplinarna priroda i složenost zadatka determinisala je sledeći niz metodoloških koraka za njegovo izvršenje: a) deskriptivna analiza procesa artikulacije, kao najvažnijeg i najsloženijeg aspekta u psiho-fiziološkom procesu produkcje govornog izraza, u svetlu definicije i komparativne analize njegovih tipičnih i atipičnih realizacija; b) karakterizacija akustičke manifestacije procesa artikulacije govornog izraza, kao pojave pogodne za posrednu analizu kvaliteta artikulacije preko instrumentalnih eksperimentalnih metoda; c) deskripcija procesa auditivne percepcije i evaluacije kvaliteta artikulacije od strane eksperta (logopeda) zasnovane na treniranom slušanju, odnosno, na sinhronizovanoj analizi skupa relevantnih artikulacionih i akustičkih atributa govornog signala, u skladu sa standardnim testovima; d) deskripcija procesa formiranja logopedskog ukupnog akustičkog utiska, odnosno akustičke slike artikulacije govormog izraza i njegove sublimacije u odgovarajuću vrednost na standardnoj numeričkoj skali ocena; e) uspostavljanja različitih modela algoritamske korespondencije između vektora akustičkih obeležja i numeričkih indikatora klasa različitog kvaliteta artikulacije što rezultuje računarskim modeliranjem procesa logopedske ocene kvaliteta artikulacije zasnovanim na inteligentnim učećim prediktorima, gde se računar nalazi u sličnom informacionom okruženju kao i logoped., The main task of the research presented in the dissertation is the modeling of the complex process of speech therapist assessment of the quality of the articulation of Serbian phonemes, based on intelligent "data driven" learning models. The multidisciplinary nature and complexity of the task determined the following set of methodological steps for its execution: a) a descriptive analysis of the articulation process, as the most important and complicated aspect of the psycho-physiological process, the production of speech expression, in the light of the definition and comparative analysis of its typical and atypical realizations; b) the characterization of an acoustic manifestation of the process of articulation of speech expression, as phenomena suitable for the indirect analysis of articulation through instrumental experimental acoustic methods; c) Describing the process of audible perception and evaluating the quality of articulation by the expert (speech therapist) based on a trained listening, or, in a synchronized analysis of a set of relevant articulation and acoustic attributes of the speech signal, in accordance with standard tests; d) the description of the process of forming the speech therapist total acoustic impression, that is, the acoustic image of the articulation of the speech term and its sublimation in the corresponding value on the standard numerical scaling scale; e) the establishment of different models of algorithmic correspondence between the acoustic feature vectors and the numerical indicators of the classes of different articulation quality, which results in computer modeling of the process of speech therapist articulation quality assessment based on intelligent learning predictors, where the computer is located in a similar information environment as well as speech therapist.

Published
2018

37. Primena neuralnih mreža u prepoznavanju šapata

Author

Šumarac Pavlović, Dragana, Mijić, Miomir, Subotić, Miško, Kvašćev, Goran, Grozdić, Đorđe T., Šumarac Pavlović, Dragana, Mijić, Miomir, Subotić, Miško, Kvašćev, Goran, and Grozdić, Đorđe T.

Abstract

Nedavno postignuti uspesi dubinskih neuralnih mreža u različitim zadacima mašinskog učenja su doprineli da vestačke neuralne mreze ponovo zauzmu bitnu ulogu u automatskom prepoznavanju govora. U ovom doktoratu je ispitana primena vestačkih neuralnih mreza u prepoznavanju šapata..., The recent success of Deep Neural Networks (DNN) in different machine learning tasks has significantly contributed to the rise in the popularity of artificial neural networks (ANN) and their today’s role in Automatic Speech Recognition (ASR). This thesis examines how artificial neural networks can benefit in automatic whispered speech recognition...

Published
2017

40. The overall knowledge of genetics in Serbian speech and language pathologists.

Author

Bogavac, Ivana, Rakonjac, Marijana, Jeličić, Ljiljana, Punišić, Silvana, and Subotić, Miško

Subjects
GENETIC disorders, EDUCATIONAL programs, EDUCATIONAL attainment, COMMUNICATIVE disorders in children, TRAIT intercorrelations
Abstract

An increase in the number of children with speech–language pathology also having a genetic disorder imposes the need for speech and language pathologists (SLPs) to have sufficient knowledge about genetic basis of speech–language disorders. Research aim was to estimate in Serbian SLPs different aspects of theoretical and practical knowledge about intercorrelation of genetics and speech and language pathology and to compare obtained results with the results of SLPs in the United States. The questionnaire from Tramontana's study was used in our study. Comparison of the results that obtained in our study with those in Tramontana's study has shown that our study respondents have higher General Knowledge Index (78.6%: 66.2%), higher mean confidence summary score (22.2: 16.7) and higher mean score of 'overall' attitudes about genetics and its relation with communication disorders (20.8: 13.6). Differences which emerge from educational programmes, educational levels and practical experience in the observed groups are indicated as possible causes of differences in the obtained results. On the basis of the obtained results, it may be concluded that it is necessary to elevate SLPs' level of general knowledge about genetics and to acquire their knowledge through clinical practice. [ABSTRACT FROM AUTHOR]

Published
2019
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41. Percepcija govora kod dece sa izmenjenim eeg nalazom

Author

Čabarkapa, Nataša, Fatić, Saška, Punišić, Silvana, and Subotić, Miško

Subjects
developmental speech and language disorders, promene elektroencefalografskih aktivnosti, language understanding, changes in electroencephalographic activity, razumevanje jezika, razvojni govorno-jezički poremećaj
Abstract

Percepcija govornog signala predstvlja izuzetno složen proces, koji se odvija od transformacije akustičkih informacija koje slušalac prima putem slušnog mehanizma do psihološke obrade određenih lingvističkih pojmova. Razumevanje govora može biti narušeno ukoliko prepoznavanje odno- sa između karakteristika akustičkog signala i fonetskih segmenata nije pravilno ili ukoliko postoje smetnje u upotrebi fonoloških, leksičkih, sintaksičkih i semantičkih pravila određenog jezika. Dakle, očuvanost čula i mehanizama prenosa informacija do viših struktura, poznavanje od- ređenih jezičkih pravila, kao i očuvanost mentalnih procesa poput pažnje i pamćenja direktno utiču na sposobnost razumevanja govora. Cilj ovog istraživanja je bio da se ispita sposobnost razumevanja jezi- ka kod dece sa razvojnim govorno-jezičkim poremećajem koja imaju promene elektroencefalografskih aktivnosti.Uzorak ispitanika je činilo 30-oro dece, uzrasta od 4 do 7 godina, sa razvojnim govorno-jezičkim poremećajem, a koja su na osnovu nalaza EEG-a bila podeljena na eksperimentalnu i kon- trolnu grupu. Rezultati istraživanja ukazuju da deca sa razvojnim govorno-jezičkim poremećajem i sa promenama elektroencefalografskih aktivnosti imaju slabiju sposobnost razumevanja jezika od dece sa razvojnim govorno-jezičkim poremećajem i bez promena elektroencefalografskih aktivnosti. Rezulta- ti ukazuju i na podatak da su devojčice uspešnije od dečaka u ovoj sposob- nosti. Perception of the speech signal represents a very complex process, which is carried by the transformation of acoustic information that the listener receives through the auditory mechanism of the psychological treatment of certain linguistic concepts. Understanding speech may be impaired if the recognition of the relationship between the characteristics of the acoustic signal and phonetic segments is not correct or if there are obstacles in the use of phonological, lexical, syntactic and semantic rules of a language. Thus, the preservation of the senses and the mechanisms of information transfer to higher structures, knowledge of certain linguistic rules, and preservation of mental processes such as attention and memory directly affect the ability to understand speech. The aim of this study was to investigate the ability of language comprehension in children with developmental speech and language disorders that have a change of electroencephalographic activity. The sample of subjects consisted of 30 children, aged 4 to 7 years, with the development of speech and language disorders, which based on the findings of the EEG was divided into experimental and control groups. The results suggest that children with developmental speech and language disorders and changes in electroencephalographic activity have less ability to understand the language of children with developmental speech and language disorders, and no change of electroencephalographic activity. The results point to the fact that girls are more successful than boys in this capacity.

Published
2014

42. Uticaj akustičkog i biološkog šuma na kvalitet merenja signala otoakustičke emisije

Author

Subotić, Miško, Jovičić, Slobodan, Mijić, Miomir, Pavlović-Šumarac, Dragana, Šarić, Zoran, and Radunović, Jovan

Subjects
Biološka osnova nastanka signala otoakusticke emisije (OAE), TEOAE, adaptive suppression of noise, biological noise, ambient noise, screening program, adaptive filter, hearing loss
Abstract

Biološka osnova nastanka signala otoakusticke emisije (OAE), akusticka priroda njegovog nastanka i izuzetna maskiranost raznim oblicima smetnji jesu polazna osnova razvoja raznih metoda detekcije, obrade i interpretacije signala OAE, odnosno samog efekta otoakusticke emisije u svetlu karakterizacije funkcionisanja kohlee. Metode merenja OAE se razlikuju po nacinu generisanja stimulusa, mehanizmima generisanja odziva kao i po nacinima obrade signala i statistickog tumacenja dobijenih rezultata. Postojece metode merenja i obrade signala OAE jesu osnova savremenih sistema za merenje OAE, koji su našli široku primenu u klinickoj praksi. Meutim, nisu iscrpljene sve mogucnosti, pre svega teorijske a zatim i metodološke prirode, prvenstveno u domenu ekstrakcije signala OAE iz šuma. Poboljšanjem uslova merenja smanjuje se uticaj spoljašnje buke (šumova) na mogucnost ekstrakcije signala otoakusticke emisije i biološki šum postaje dominantan izvor smetnji. Istraživanje karakteristika bioloških šumova je jedan od preduslova za uspešno rešavanje problema detekcije OAE u prisustvu biološkog šuma. Na pažljivo odabranom uzorku, u skladu sa potrebama istraživanja, analizirani su biološki šumovi snimljeni u ušnom kanalu. Pokazalo se da postoji znacajna korelacija bioloških šumova u levom i desnom uhu i da koeficijent korelacije raste sa porastom intenziteta bioloških šumova. Ovakvo ponašanje bioloških šumova predstavlja povoljnu okolnost sa stanovišta primene adaptivnih metoda filtriranja i adaptivnih metoda potiskivanja šuma. U disertaciji su analizirane karakteristike najznacajnijih bioloških smetnji koje su prisutne kod merenja signala OAE. Ova saznanja su omogucila izbor optimalane adaptivne metode za detekciju TEOAE u prisustvu biološkog šuma. Osnovna ideja za potiskivanje biološkog šuma sastojala se u korišcenju biološkog šuma iz drugog ušnog c kanala za adaptivno potiskivanje biološkog šuma u ušnom kanalu u kome se meri OAE signal. Pošto je signal OAE duboko uronjen u šum, neophodno je bilo kombinovati nekoliko postupaka u toku predobrade signala kako bi se postiglo dobro potiskivanje šuma. Primenjeni su postupci adaptivnog filtriranja, ponderisanog usrednjavanja i oduzimanja procenjene vrednosti signala OAE od signala odziva snimljenog u ušnom kanalu... Biological basis of the otoacoustic emission signal (OAE), acoustic nature of its generation and exceptional masking with various forms of interference are the starting point for the development of various methods of detection, signal processing and interpretation of OAE signal, or the effect of otoacoustic emission in light of the characterization of the cochlea functioning. OAE measurement methods differ in the way of stimulus generation, response generation mechanisms and the methods of signal processing and statistical interpretation of results. Existing methods of measurement and OAE signal processing are the basis of modern systems for OAE measurement, which have found wide application in clinical practice. However, all possibilities are not exhausted, especially the theoretical and methodological nature aproaches, primarily in the field of OAE signal extraction from the noise. Improvement of the measuring conditions reduces the influence of external noise on the possibility of extraction of otoacoustic emissions, and biological noise becomes the dominant source of interference. The study of characteristics of biological noise is one of the prerequisites for successful troubleshooting OAE detection in the presence of biological noise. In carefully selected sample, in accordance with the needs of research, we analyzed the biological noise recorded in the ear canal. It turned out that there was a significant correlation of biological noise in the left and right ear and the correlation coefficient increases with the intensity of biological noise. This behavior of biological noise is a favorable circumstance from the point of application of adaptive filtering methods and adaptive noise suppression method. The dissertation analyzes the characteristics of the most important form of biological interference that are present during OAE measurement. These findings have enabled the selection of optimal adaptive methods for the detection of TEOAE in the presence of biological noise. The basic idea of suppressing biological noise consisted in e the use of biological noise from the other ear canal for adaptive suppression of biological noise in the ear canal in which OAE signal is measured. Since the OAE signal is deeply immersed in the noise it was necessary to combine several steps during preprocessing the signal to achieve good noise suppression. The applied methods are adaptive filtering, weighted averaging and estimated value of OAE signal subtraction from the signal response recorded in the ear canal...

Published
2013

43. Specifičnosti govora i jezika kod dece Sa izmenjenim eeg nalazom

Author

Fatić, Saška, Čabarkapa, Nataša, Punišić, Silvana, and Subotić, Miško

Subjects
govor, EEG, jezik, razvojna disfazija, developmental dysphasia, speech, language
Abstract

Pod jezikom se podrazumeva složeni sistem kodova koji označavaju pred- mete, simbole, radnje ili odnose koji nose funkciju kodiranja, prenosa in- formacije i njenog uvođenja u različite sisteme, dok reč predstavlja osnovno sredstvo kodiranja i prenošenja iskustva. Jezik je, dakle, apstraktan si- stem, a govor njegova konkretna realizacija. Kod dece sa razvojnim jezičkim poremećajima javljaju se smetnje na pla- nu razumevanja, upotrebe i izražavanja jezika u različitom stepenu u jednoj Ili u svim oblastima fonologije, semantike, sintakse i pragmatike. Za- stoj ili kašnjenje u razvoju jezičke strukture može biti jedan od pokazate- lja disfunkcije određenih moždanih oblasti. Ovi podaci ukazuju na značajj ispitivanja jezičkih funkcija u odnosu na funkcionisanje Centralnog ner- vnog sistema. Imajuci to u vidu, za predmet ovog rada odabrano je ispiti- vanje govora i jezika kod dece sa razvojnom disfazijom i izmenjenim EEG-om. Osnovni cilj ovog istraživanja je da se utvrdi nivo razvijenosti govora i jezika kod dece sa izmenjenim EEG nalazom, ali da se ispita i odnos dobije- nih rezultata među polovima. Uzorak je činilo 15-oro dece sa patološkim EEG nalazom i 15-oro dece sa urednim EEG-om. U istraživanju su korišćeni sledeći merni instrumenti: Globalni artikulacioni test, Test verbal- nog pamćenja i Test za procenu imenica prvog nivoa apstrakcije. Svi podaci su grafički obrađeni i prikazani. Rezultati su ukazali da su deca sa urednim EEG-om imali bolja postig- nuća na skoro svim testovima, ali i da je eksperimentalnoj grupi klinička slika teža kod dečaka nego kod devojčica. Under the language implies a complex system of codes which denote objects, symbols, actions or relationships that carry the coding function, the transfer of information and its implementation in a variety of systems, and the word is the primary means of coding and transmission experience. It was, therefore, an abstract system and its concrete realization of speech. In children with developmental language disorders occurring interference in terms of understanding and use of language and expression to varying degrees in one or all areas of phonology, semantics, syntax and pragmatics. Suspension or delay in the development of linguistic structure can be an indicator of dysfunction of specific brain areas. These data highlight the importance of testing language functions in relation to the functioning of the central nervous system. With that in mind, the purpose of this paper is to examine selected speech and language in children with developmental dysphasia and altered EEG. The main objective of this study was to determine the level of development of speech and language in children with altered EEG findings, but to examine the relationship of the results between the sexes. The sample consisted of 15 children with abnormal EEG findings, and 15 children with normal EEGs. The survey used the following measuring instruments: the global articulation test, Test Verbal Learning Test for assessing the first level of abstraction of nouns. All data were analyzed and presented graphically. The results indicated that children with normal EEGs had better achievements in almost all tests, but the experimental group clinical harder for boy

Published
2013

44. Specific features of brain connectivity during silent reading in children with developmental dyslexia

Author

Stokić, Miodrag, Milosavljević, Zorana, and Subotić, Miško

Subjects
konekcije moždanih regija, Brain Connectivity, razvojna disleksija, Theta Band, neuralne mreže, Developmental dyslexia, EEG, teta ritam, Neuronal Networks
Abstract

Numerous studies have used electrophysiological methods in attempts to discriminate dyslexic from non-dyslexic readers and to identify brain mechanisms underlying specific reading disability. The aim of the present study is to apply an analysis of largescale neuronal networks to study brain connectivity in children with developmental dyslexia during silent reading and to compare results with their peers. EEG signal was recorded from five dyslexic and five normal readers (three female and two male) using 10-20 International system for electrode placement and mono-polar montage. Additional EOG electrodes were used in order to register horizontal and vertical eye movements. Subjects had a task to read a simple story silently. The text was presented on a computer screen with 40 cm distance from the subject’s eyes. Five-second artefact free periods were analysed offline using spectral analysis (FFT algorithm). Amplitude correlations in Theta rhythm (4-7 Hz) between all 19 electrodes were calculated. Statistically significant correlations (p=0.01) were further used for neural network modelling.We found that dyslexic children had one closed neural network that consisted of four elements (centro-parietal cortex: C3-C4- Cz-P4 electrodes) and three interhemispheric connections between homologous electrodes without complex intra- and interhemispheric connections. Non-dyslexic readers had far more, both quantitatively and qualitatively, complex large-scale neuronal networks in frontotemporal and centro-parietal cortex. Complex cognitive functions, such as reading, require dynamic collaboration between close and distant cortical regions in order to achieve adequate connections for parallel information processing. Brojne studije koristile su elektrofiziološke metode u pokušaju da diferenciraju decu sa razvojnom disleksijom od tipičnih čitača kao i da identifikuju mehanizme koji su u osnovi razvojne disleksije. Cilj ove studije bio je da se ispitaju karakteristike povezivanja moždanih regija u lokalne i široko-distribuirane neuralne mreže kod dece sa razvojnom disleksijom tokom čitanja u sebi i da se rezultati uporede sa rezultatima dece urednih čitača. EEG signal je snimljen kod petoro dece sa razvojnom disleksijom (2 dečaka i 3 devojčice) i pet urednih čitača iste polne i uzrasne strukture, koristeći 10-20 Internacionalni sistem za pozicioniranje elektroda uz monopolarnu montažu. Dodatne elektrode su korišćene kako bi se registrovali pokreti očiju. Ispitanici su imali zadatak da u sebi čitaju jednostavan tekst. Tekst je prezentovan na monitoru računara na udaljenosti od 40cm od očiju ispitanika. Periodi od 5 sekundi bez artefakata analizirani su spektralnom analizom (FFT-Fast Fourier Transform algoritam). Statistički značajne (p

Published
2011

47. Uticaj akustičkog i biološkog šuma na kvalitet merenja signala otoakustičke emisije

Author

Jovičić, Slobodan, Mijić, Miomir, Pavlović-Šumarac, Dragana, Šarić, Zoran, Radunović, Jovan, Subotić, Miško, Jovičić, Slobodan, Mijić, Miomir, Pavlović-Šumarac, Dragana, Šarić, Zoran, Radunović, Jovan, and Subotić, Miško

Abstract

Biološka osnova nastanka signala otoakusticke emisije (OAE), akusticka priroda njegovog nastanka i izuzetna maskiranost raznim oblicima smetnji jesu polazna osnova razvoja raznih metoda detekcije, obrade i interpretacije signala OAE, odnosno samog efekta otoakusticke emisije u svetlu karakterizacije funkcionisanja kohlee. Metode merenja OAE se razlikuju po nacinu generisanja stimulusa, mehanizmima generisanja odziva kao i po nacinima obrade signala i statistickog tumacenja dobijenih rezultata. Postojece metode merenja i obrade signala OAE jesu osnova savremenih sistema za merenje OAE, koji su našli široku primenu u klinickoj praksi. Meutim, nisu iscrpljene sve mogucnosti, pre svega teorijske a zatim i metodološke prirode, prvenstveno u domenu ekstrakcije signala OAE iz šuma. Poboljšanjem uslova merenja smanjuje se uticaj spoljašnje buke (šumova) na mogucnost ekstrakcije signala otoakusticke emisije i biološki šum postaje dominantan izvor smetnji. Istraživanje karakteristika bioloških šumova je jedan od preduslova za uspešno rešavanje problema detekcije OAE u prisustvu biološkog šuma. Na pažljivo odabranom uzorku, u skladu sa potrebama istraživanja, analizirani su biološki šumovi snimljeni u ušnom kanalu. Pokazalo se da postoji znacajna korelacija bioloških šumova u levom i desnom uhu i da koeficijent korelacije raste sa porastom intenziteta bioloških šumova. Ovakvo ponašanje bioloških šumova predstavlja povoljnu okolnost sa stanovišta primene adaptivnih metoda filtriranja i adaptivnih metoda potiskivanja šuma. U disertaciji su analizirane karakteristike najznacajnijih bioloških smetnji koje su prisutne kod merenja signala OAE. Ova saznanja su omogucila izbor optimalane adaptivne metode za detekciju TEOAE u prisustvu biološkog šuma. Osnovna ideja za potiskivanje biološkog šuma sastojala se u korišcenju biološkog šuma iz drugog ušnog c kanala za adaptivno potiskivanje biološkog šuma u ušnom kanalu u kome se meri OAE signal. Pošto je signal OAE duboko uronjen u šum, ne, Biological basis of the otoacoustic emission signal (OAE), acoustic nature of its generation and exceptional masking with various forms of interference are the starting point for the development of various methods of detection, signal processing and interpretation of OAE signal, or the effect of otoacoustic emission in light of the characterization of the cochlea functioning. OAE measurement methods differ in the way of stimulus generation, response generation mechanisms and the methods of signal processing and statistical interpretation of results. Existing methods of measurement and OAE signal processing are the basis of modern systems for OAE measurement, which have found wide application in clinical practice. However, all possibilities are not exhausted, especially the theoretical and methodological nature aproaches, primarily in the field of OAE signal extraction from the noise. Improvement of the measuring conditions reduces the influence of external noise on the possibility of extraction of otoacoustic emissions, and biological noise becomes the dominant source of interference. The study of characteristics of biological noise is one of the prerequisites for successful troubleshooting OAE detection in the presence of biological noise. In carefully selected sample, in accordance with the needs of research, we analyzed the biological noise recorded in the ear canal. It turned out that there was a significant correlation of biological noise in the left and right ear and the correlation coefficient increases with the intensity of biological noise. This behavior of biological noise is a favorable circumstance from the point of application of adaptive filtering methods and adaptive noise suppression method. The dissertation analyzes the characteristics of the most important form of biological interference that are present during OAE measurement. These findings have enabled the selection of optimal adaptive methods for the detection of TEOAE in the presence of biolog

Published
2013

49. NEUROREHABILITATION OF ALEXIA WITHOUT AGRAPHIA - A CASE REPORT.

Author

TOMIĆ, Gordana, NIKOLIĆ, Jelena, PUNIŠIĆ, Silvana, SUBOTIĆ, Miško, and ZIDVERC TRAJKOVIĆ, Jasna

Subjects
*MILD cognitive impairment, *DIAGNOSTIC examinations, *NEUROREHABILITATION, *AGENESIS of corpus callosum, *CORPUS callosum, *SPEECH
Abstract

Introduction. Alexia without agraphia is an impairment of reading ability. Speech, auditory comprehension, repetition and writing are relatively intact. Due to a damage of the splenium of corpus callosum, alexia without agraphia is considered to be an interhemispheric disconnection syndrome. Case Report. We presented a 71-year-old male, with chronic hypertension, diabetes mellitus and dyslipidemia. The magnetic resonance imaging showed a lesion in the left medial temporal region, including the equilateral thalamus, posterior cingulate gyrus, splenium of corpus callosum, lingual occipital gyrus, and the tail of the hippocampus. Lacunar ischemia was found on the right side of cerebellum. The neuro-linguistic diagnostic protocol included the Mini Mental State Examination, Boston Diagnostic Aphasia Examination, Boston Naming Test and phonemic and category fluency tests. We have also designed a clinical protocol for color recognition assessment. The results showed a mild cognitive impairment related to the time and space orientation, delayed memory and reading. On the speech and language levels, a severe acquired alexia without agraphia was registered which was not associated with other language modalities. Conclusion. The neuro-linguistic tests and clinical techniques provide a rather reliable diagnostic criteria, which is the basis for neuro-rehabilitation. The rehabilitation protocol refers to training techniques: tactile-kinesthetic recognition of graphemes and application of various reading techniques, such as letter-by-letter reading, Multiple Oral Re-reading, melodic intonation therapy and oral reading technique in order to facilitate rehabilitation of reading. [ABSTRACT FROM AUTHOR]

Published
2018
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50. Individual or Group Verbotonal Phonetic Correction – Which One Is Better?

Author

Dobrić, Arnalda, Haičman, Matea, Subotić, Miško, and Maksimović, Slavice

Subjects
voiceless dental fricative /s, individual and group phonetic training, the verbotonal method
Abstract

In this pilot study main similarities and differences between individual and group sessions of phonetic correction using verbotonal methods are discussed on the basis of their outcomes. Four speakers who started to learn Croatian as foreign language participated in 10 sessions of individual (1 speaker) or group (3 speakers) phonetic correction, respectively, during the initial level language course. The main purpose of the sessions was the improvement of pronunciation of Croatian fricative /s/ that was not adequately pronounced in any of the speakers resulting therefore in misunderstanding or insufficient speech quality. Furthermore, some time in the beginning of each session was dedicated to the work on global form of speech (rhythm and intonation) since the rhythm and intonation present in each speech would easily reveal speaker's native language. The sessions were established following main principles of the verbotonal method – listening as the basis of speech acquisition, wholeness of the structure and filtering speech in order to enhance better pronunciation. The results of the phonetic correction training were compared on the basis of the perceptive test performed by 2 trained listeners. The listeners participated in the listening of selected words recorded before and after sessions of the verbotonal phonetic correction without any knowledge whether the person attended individual or group classes although they had had the information on the two possibilities before the test. The results show that the words recorded after the correction were defined as more acceptable or pronounced by a native speaker and the answers depended partly on the position of the sound /s/ in the word.

Published
2019

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