478 results on '"Sancho E"'
Search Results
2. Competency assessment of residents of Intensive Care Medicine through a simulation-based objective structured clinical evaluation (OSCE). A multicenter observational study
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Castellanos-Ortega, Á., Broch, M.J., Palacios-Castañeda, D., Gómez-Tello, V., Valdivia, M., Vicent, C., Madrid, I., Martinez, N., Párraga, M.J., Sancho, E., Fuentes-Dura, M.d.C., Sancerni-Beitia, M.D., and García-Ros, R.
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- 2022
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3. Clinical practice guidelines for the diagnosis and management of Charcot-Marie-Tooth disease
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Sivera Mascaró, R., primary, García Sobrino, T., additional, Horga Hernández, A., additional, Pelayo Negro, A.L., additional, Alonso Jiménez, A., additional, Antelo Pose, A., additional, Calabria Gallego, M.D., additional, Casasnovas, C., additional, Cemillán Fernández, C.A., additional, Esteban Pérez, J., additional, Fenollar Cortés, M., additional, Frasquet Carrera, M., additional, Gallano Petit, M.P., additional, Giménez Muñoz, A., additional, Gutiérrez Gutiérrez, G., additional, Gutiérrez Martínez, A., additional, Juntas Morales, R., additional, Ciano-Petersen, N.L., additional, Martínez Ulloa, P.L., additional, Mederer Hengstl, S., additional, Millet Sancho, E., additional, Navacerrada Barrero, F.J., additional, Navarrete Faubel, F.E., additional, Pardo Fernández, J., additional, Pascual Pascual, S.I., additional, Pérez Lucas, J., additional, Pino Mínguez, J., additional, Rabasa Pérez, M., additional, Sánchez González, M., additional, Sotoca, J., additional, Rodríguez Santiago, B., additional, Rojas García, R., additional, Turon-Sans, J., additional, Vicent Carsí, V., additional, and Sevilla Mantecón, T., additional
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- 2024
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4. Acute respiratory distress syndrome due to COVID-19. Clinical and prognostic features from a medical Critical Care Unit in Valencia, Spain
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Ramírez, P., Gordón, M., Martín-Cerezuela, M., Villarreal, E., Sancho, E., Padrós, M., Frasquet, J., Leyva, G., Molina, I., Barrios, M., Gimeno, S., and Castellanos, Á.
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- 2021
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5. Differences in the disclosure of a cancer diagnosis by healthcare professionals and the repercussions on patients’ emotions and health
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Sancho, E. Ruiz, primary, Nieto, M.A. Pérez, additional, Román, F., additional, León, L., additional, Escamilla, F. Sánchez, additional, Francés, S. Enrech, additional, Escutia, M.A. Pérez, additional, Martel, I. Juez, additional, Pérez-Segura, P., additional, Aguirre, A., additional, and Delgado, M. Redondo, additional
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- 2023
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6. Recent human-induced atmospheric drying across Europe unprecedented in the last 400 years
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Treydte, K., Liu, L., Padrón, R.S., Martínez-Sancho, E., Babst, F., Frank, D.C., Gessler, A., Kahmen, A., Poulter, B., Seneviratne, S.I., Stegehuis, A.I., Wilson, R., Andreu-Hayles, L., Bale, R., Bednarz, Z., Boettger, Tatjana, Berninger, F., Büntgen, U., Daux, V., Dorado-Liñán, I., Esper, J., Friedrich, M., Gagen, M., Grabner, M., Grudd, H., Gunnarsson, B.E., Gutiérrez, E., Hafner, P., Haupt, Marika, Hilasvuori, E., Heinrich, I., Helle, G., Jalkanen, R., Jungner, H., Kalela-Brundin, M., Kessler, A., Kirchhefer, A., Klesse, S., Krapiec, M., Levanič, T., Leuenberger, M., Linderholm, H.W., McCarroll, D., Masson-Delmotte, V., Pawelczyk, S., Pazdur, A., Planells, O., Pukiene, R., Rinne-Garmston, K.T., Robertson, I., Saracino, A., Saurer, M., Schleser, G.H., Seftigen, K., Siegwolf, R.T.W., Sonninen, E., Stievenard, M., Szychowska-Krapiec, E., Szymaszek, M., Todaro, L., Waterhouse, J.S., Weigl-Kuska, M., Weigt, R.B., Wimmer, R., Woodley, E.J., Vitas, A., Young, G., Loader, N.J., Treydte, K., Liu, L., Padrón, R.S., Martínez-Sancho, E., Babst, F., Frank, D.C., Gessler, A., Kahmen, A., Poulter, B., Seneviratne, S.I., Stegehuis, A.I., Wilson, R., Andreu-Hayles, L., Bale, R., Bednarz, Z., Boettger, Tatjana, Berninger, F., Büntgen, U., Daux, V., Dorado-Liñán, I., Esper, J., Friedrich, M., Gagen, M., Grabner, M., Grudd, H., Gunnarsson, B.E., Gutiérrez, E., Hafner, P., Haupt, Marika, Hilasvuori, E., Heinrich, I., Helle, G., Jalkanen, R., Jungner, H., Kalela-Brundin, M., Kessler, A., Kirchhefer, A., Klesse, S., Krapiec, M., Levanič, T., Leuenberger, M., Linderholm, H.W., McCarroll, D., Masson-Delmotte, V., Pawelczyk, S., Pazdur, A., Planells, O., Pukiene, R., Rinne-Garmston, K.T., Robertson, I., Saracino, A., Saurer, M., Schleser, G.H., Seftigen, K., Siegwolf, R.T.W., Sonninen, E., Stievenard, M., Szychowska-Krapiec, E., Szymaszek, M., Todaro, L., Waterhouse, J.S., Weigl-Kuska, M., Weigt, R.B., Wimmer, R., Woodley, E.J., Vitas, A., Young, G., and Loader, N.J.
- Abstract
The vapor pressure deficit reflects the difference between how much moisture the atmosphere could and actually does hold, a factor that fundamentally affects evapotranspiration, ecosystem functioning, and vegetation carbon uptake. Its spatial variability and long-term trends under natural versus human-influenced climate are poorly known despite being essential for predicting future effects on natural ecosystems and human societies such as crop yield, wildfires, and health. Here we combine regionally distinct reconstructions of pre-industrial summer vapor pressure deficit variability from Europe’s largest oxygen-isotope network of tree-ring cellulose with observational records and Earth system model simulations with and without human forcing included. We demonstrate that an intensification of atmospheric drying during the recent decades across different European target regions is unprecedented in a pre-industrial context and that it is attributed to human influence with more than 98% probability. The magnitude of this trend is largest in Western and Central Europe, the Alps and Pyrenees region, and the smallest in southern Fennoscandia. In view of the extreme drought and compound events of the recent years, further atmospheric drying poses an enhanced risk to vegetation, specifically in the densely populated areas of the European temperate lowlands.
- Published
- 2023
7. Angry rumination as a mediator of the relationship between ability emotional intelligence and various types of aggression
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García-Sancho, E., Salguero, J.M., and Fernández-Berrocal, P.
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- 2016
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8. Taxogenetics of the saccharomyces sensu stricto yeasts from western and south Africa
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Naumov, G I, Naumova, E S, Sancho, E D, Korhola, M, and BioStor
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- 1993
9. Anxiety, depression and coping styles following cancer diagnosis communicated by oncologists before and after receiving training in delivering bad news
- Author
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Herrero, A. Aguirre, primary, Escamilla, F. Sánchez, additional, Nieto, M.Á. Pérez, additional, Delgado, M.M. Redondo, additional, Sancho, E. Ruiz, additional, Román, F.J., additional, Escobar, E. Rubio, additional, León, L., additional, Francés, S. Enrech, additional, Escutia, M.Á. Pérez, additional, Martel, I. Juez, additional, and Pérez-Segura, P., additional
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- 2023
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10. Relationship between emotional intelligence and aggression: A systematic review
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García-Sancho, E., Salguero, J.M., and Fernández-Berrocal, P.
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- 2014
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11. Climate Signals in Stable IsotopeTree-RingRecords
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Gagen M, Battipaglia Giovanna, Daux V, Duffy J, Dorado-Liñán I, Andreu Hayles L, Martínez-Sancho E, McCarroll. D, Shestakova T, Treydte K, Siegwolf TTW, Brooks JR, Roden J, Saurer M, Gagen, M, Battipaglia, Giovanna, Daux, V, Duffy, J, Dorado-Liñán, I, Andreu Hayles, L, Martínez-Sancho, E, Mccarrol, l. D., Shestakova, T, and Treydte, K
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- 2022
12. Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy
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Álvarez-Varela, A., Novellasdemunt, l., Barriga, F.M., Hernando-Momblona, X., Cañellas-Socias, A., Cano-Crespo, S., Sevillano, M., Cortina, C., Stork, d., Morral, C., Turon, G., Slebe, F., Jiménez-Gracia, L., Caratù, G., Jung, P., Stassi, G., Heyn, H., Tauriello, D.V.F., Mateo, L., Tejpar, S., Sancho, E., E., S.-O., Batll, A.E., Álvarez-Varela, A., Novellasdemunt, l., Barriga, F.M., Hernando-Momblona, X., Cañellas-Socias, A., Cano-Crespo, S., Sevillano, M., Cortina, C., Stork, d., Morral, C., Turon, G., Slebe, F., Jiménez-Gracia, L., Caratù, G., Jung, P., Stassi, G., Heyn, H., Tauriello, D.V.F., Mateo, L., Tejpar, S., Sancho, E., E., S.-O., and Batll, A.E.
- Abstract
Item does not contain fulltext
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- 2022
13. Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells
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Cañellas-Socias, A., Cortina, C., Hernando-Momblona, X., Palomo-Ponce, S., Mulholland, E.J., Turon, G., Mateo, L., Conti, S., Roman, O., Sevillano, M., Slebe, F., Stork, d., Caballé-Mestres, A., Berenguer-Llergo, A., Álvarez-Varela, A., Fenderico, A., Novellasdemunt, l., Jiménez-Gracia, L., Sipka, T., Bardia, L., Lorden, P., Colombelli, J., Heyn, H., Trepat, X., Tejpar, S., Sancho, E., Tauriello, D.V.F., Leedham, S., Stephan-Otto Attolini, C., Batlle, E., Cañellas-Socias, A., Cortina, C., Hernando-Momblona, X., Palomo-Ponce, S., Mulholland, E.J., Turon, G., Mateo, L., Conti, S., Roman, O., Sevillano, M., Slebe, F., Stork, d., Caballé-Mestres, A., Berenguer-Llergo, A., Álvarez-Varela, A., Fenderico, A., Novellasdemunt, l., Jiménez-Gracia, L., Sipka, T., Bardia, L., Lorden, P., Colombelli, J., Heyn, H., Trepat, X., Tejpar, S., Sancho, E., Tauriello, D.V.F., Leedham, S., Stephan-Otto Attolini, C., and Batlle, E.
- Abstract
Item does not contain fulltext
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- 2022
14. Jet stream position explains regional anomalies in European beech forest productivity and tree growth
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Dorado Liñán, Isabel, Ayarzagüena, B., Babst, Flurin, Xu, G., Gil, L., Battipaglia, G., Buras, A., Čada, V., Camarero, J.J., Cavin, L., Claessens, H., Drobyshev, I., Garamszegi, B., Grabner, M., Hacket Pain, A., Hartl, C., Hevia, A., Janda, P., Jump, A.S., Kazimirovic, M., Keren, S., Kreyling, J., Land, A., Latte, N., Levanič, T., van der Maaten, E., van der Maaten Theunissen, M., Martínez Sancho, E., Menzel, A., Mikoláš, M., Motta, R., Muffler, L., Nola, P., Panayotov, M., Petritan, A.M., Petritan, I.C., Popa, I., Prislan, P., Roibu, C.-C., Rydval, M., Sánchez Salguero, R., Scharnweber, T., Stajić, B., Svoboda, M., Tegel, W., Teodosiu, M., Toromani, E., Trotsiuk, V., Turcu, D.-O., Weigel, R., Wilmking, M., Zang, C., Zlatanov, T., Trouet, V., Dorado Liñán, Isabel, Ayarzagüena, B., Babst, Flurin, Xu, G., Gil, L., Battipaglia, G., Buras, A., Čada, V., Camarero, J.J., Cavin, L., Claessens, H., Drobyshev, I., Garamszegi, B., Grabner, M., Hacket Pain, A., Hartl, C., Hevia, A., Janda, P., Jump, A.S., Kazimirovic, M., Keren, S., Kreyling, J., Land, A., Latte, N., Levanič, T., van der Maaten, E., van der Maaten Theunissen, M., Martínez Sancho, E., Menzel, A., Mikoláš, M., Motta, R., Muffler, L., Nola, P., Panayotov, M., Petritan, A.M., Petritan, I.C., Popa, I., Prislan, P., Roibu, C.-C., Rydval, M., Sánchez Salguero, R., Scharnweber, T., Stajić, B., Svoboda, M., Tegel, W., Teodosiu, M., Toromani, E., Trotsiuk, V., Turcu, D.-O., Weigel, R., Wilmking, M., Zang, C., Zlatanov, T., and Trouet, V.
- Abstract
The mechanistic pathways connecting ocean-atmosphere variability and terrestrial productivity are well-established theoretically, but remain challenging to quantify empirically. Such quantification will greatly improve the assessment and prediction of changes in terrestrial carbon sequestration in response to dynamically induced climatic extremes. The jet stream latitude (JSL) over the North Atlantic-European domain provides a synthetic and robust physical framework that integrates climate variability not accounted for by atmospheric circulation patterns alone. Surface climate impacts of north-south summer JSL displacements are not uniform across Europe, but rather create a northwestern-southeastern dipole in forest productivity and radial-growth anomalies. Summer JSL variability over the eastern North Atlantic-European domain (5-40E) exerts the strongest impact on European beech, inducing anomalies of up to 30 in modelled gross primary productivity and 50 in radial tree growth. The net effects of JSL movements on terrestrial carbon fluxes depend on forest density, carbon stocks, and productivity imbalances across biogeographic regions.
- Published
- 2022
15. The unknown third – Hydrogen isotopes in tree-ring cellulose across Europe
- Author
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Vitali, V., primary, Martínez-Sancho, E., additional, Treydte, K., additional, Andreu-Hayles, L., additional, Dorado-Liñán, I., additional, Gutierrez, E., additional, Helle, G., additional, Leuenberger, M., additional, Loader, N.J., additional, Rinne-Garmston, K.T., additional, Schleser, G.H., additional, Allen, S., additional, Waterhouse, J.S., additional, Saurer, M., additional, and Lehmann, M.M., additional
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- 2022
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- View/download PDF
16. The unknown third – Hydrogen isotopes in tree-ring cellulose across Europe
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Vitali, V., Martínez-Sancho, E., Treydte, K., Andreu-Hayles, L., Dorado-Liñán, I., Gutierrez, E., Helle, G., Leuenberger, M., Loader, N., Rinne-Garmston, K., Schleser, G., Allen, S., Waterhouse, J., Saurer, M., and Lehmann, M.
- Subjects
0106 biological sciences ,Carbon Isotopes ,Environmental Engineering ,010504 meteorology & atmospheric sciences ,15. Life on land ,Forests ,Oxygen Isotopes ,01 natural sciences ,Pollution ,Trees ,13. Climate action ,Environmental Chemistry ,ddc:610 ,Cellulose ,Waste Management and Disposal ,010606 plant biology & botany ,0105 earth and related environmental sciences ,Hydrogen - Abstract
This is the first Europe-wide comprehensive assessment of the climatological and physiological information recorded by hydrogen isotope ratios in tree-ring cellulose (δ2Hc) based on a unique collection of annually resolved 100-year tree-ring records of two genera (Pinus and Quercus) from 17 sites (36°N to 68°N). We observed that the high-frequency climate signals in the δ2Hc chronologies were weaker than those recorded in carbon (δ13Cc) and oxygen isotope signals (δ18Oc) but similar to the tree-ring width ones (TRW). The δ2Hc climate signal strength varied across the continent and was stronger and more consistent for Pinus than for Quercus. For both genera, years with extremely dry summer conditions caused a significant 2H-enrichment in tree-ring cellulose.\ud \ud The δ2Hc inter-annual variability was strongly site-specific, as a result of the imprinting of climate and hydrology, but also physiological mechanisms and tree growth. To differentiate between environmental and physiological signals in δ2Hc, we investigated its relationships with δ18Oc and TRW. We found significant negative relationships between δ2Hc and TRW (7 sites), and positive ones between δ2Hc and δ18Oc (10 sites). The strength of these relationships was nonlinearly related to temperature and precipitation. Mechanistic δ2Hc models performed well for both genera at continental scale simulating average values, but they failed on capturing year-to-year δ2Hc variations. Our results suggest that the information recorded by δ2Hc is significantly different from that of δ18Oc, and has a stronger physiological component independent from climate, possibly related to the use of carbohydrate reserves for growth. Advancements in the understanding of 2H-fractionations and their relationships with climate, physiology, and species-specific traits are needed to improve the modelling and interpretation accuracy of δ2Hc. Such advancements could lead to new insights into trees' carbon allocation mechanisms, and responses to abiotic and biotic stress conditions.
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- 2022
17. High dielectric permittivity of SrBi2Nb2O9(SBN) added Bi2O3 and La2O3
- Author
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Sancho, E. O., Silva, P. M. O., Júnior, G. F. M. Pires, Rodrigues, H. O., Freitas, D. B., and Sombra, A. S. B.
- Published
- 2013
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18. The GenTree Leaf Collection:inter‐ and intraspecific leaf variation in seven forest tree species in Europe
- Author
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Benavides, R. (Raquel), Carvalho, B. (Barbara), Bastias, C. C. (Cristina C.), Lopez-Quiroga, D. (David), Mas, A. (Antonio), Cavers, S. (Stephen), Gray, A. (Alan), Albet, A. (Audrey), Alia, R. (Ricardo), Ambrosio, O. (Olivier), Aravanopoulos, F. (Filippos), Aunon, F. (Francisco), Avanzi, C. (Camilla), Avramidou, E. V. (Evangelia V.), Bagnoli, F. (Francesca), Ballesteros, E. (Eduardo), Barbas, E. (Evangelos), Bastien, C. (Catherine), Bernier, F. (Frederic), Bignalet, H. (Henry), Bouic, D. (Damien), Brunetto, W. (William), Buchovska, J. (Jurata), Cabanillas-Saldana, A. M. (Ana M.), Cheval, N. (Nicolas), Climent, J. M. (Jose M.), Correard, M. (Marianne), Cremer, E. (Eva), Danusevicius, D. (Darius), Dauphin, B. (Benjamin), Del Cano, F. (Fernando), Denou, J.-L. (Jean-Luc), Dokhelar, B. (Bernard), Dourthe, R. (Remi), Farsakoglou, A.-M. (Anna-Maria), Fera, A. (Andreas), Fonti, P. (Patrick), Ganopoulos, I. (Ioannis), Garcia del Barrio, J. M. (Jose M.), Gilg, O. (Olivier), Gonzalez-Martinez, S. C. (Santiago C.), Graf, R. (Rene), Grivet, D. (Delphine), Gugerli, F. (Felix), Hartleitner, C. (Christoph), Heer, K. (Katrin), Hollenbach, E. (Enja), Hurel, A. (Agathe), Issehuth, B. (Bernard), Jean, F. (Florence), Jorge, V. (Veronique), Jouineau, A. (Arnaud), Kappner, J.-P. (Jan-Philipp), Kärkkainen, K. (Katri), Kesälahti, R. (Robert), Knutzen, F. (Florian), Kujala, S. T. (Sonja T.), Kumpula, T. (Timo), Labriola, M. (Mariaceleste), Lalanne, C. (Celine), Lambertz, J. (Johannes), Lascoux, M. (Martin), Le Provost, G. (Gregoire), Liesebach, M. (Mirko), Malliarou, E. (Ermioni), Marchon, J. (Jeremy), Mariotte, N. (Nicolas), Martinez-Sancho, E. (Elisabet), Matesanz, S. (Silvia), Meischner, H. (Helge), Michotey, C. (Celia), Milesi, P. (Pascal), Morganti, S. (Sandro), Myking, T. (Tor), Nilsen, A. E. (Anne E.), Notivol, E. (Eduardo), Opgenoorth, L. (Lars), ostreng, G. (Geir), Pakull, B. (Birte), Piotti, A. (Andrea), Plomion, C. (Christophe), Poinot, N. (Nicolas), Pringarbe, M. (Mehdi), Puzos, L. (Luc), Pyhajarvi, T. (Tanja), Raffin, A. (Annie), Ramirez-Valiente, J. A. (Jose A.), Rellstab, C. (Christian), Richter, S. (Sebastian), Robledo-Arnuncio, J. J. (Juan J.), San Segundo, S. (Sergio), Savolainen, O. (Outi), Schneck, V. (Volker), Schueler, S. (Silvio), Scotti, I. (Ivan), Semerikov, V. (Vladimir), Henrik Sonstebo, J. (Jorn), Spanu, I. (Ilaria), Thevenet, J. (Jean), Tollefsrud, M. M. (Mari Mette), Turion, N. (Norbert), Vendramin, G. G. (Giovanni Giuseppe), Villar, M. (Marc), Westin, J. (Johan), Fady, B. (Bruno), and Valladares, F. (Fernando)
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tree species ,leaf economics spectrum ,leaf functional traits ,phenotypic variation ,intraspecific variability ,European forests - Abstract
Motivation: Trait variation within species can reveal plastic and/or genetic responses to environmental gradients, and may indicate where local adaptation has occurred. Here, we present a dataset of rangewide variation in leaf traits from seven of the most ecologically and economically important tree species in Europe. Sample collection and trait assessment are embedded in the GenTree project (EU‐Horizon 2020), which aims at characterizing the genetic and phenotypic variability of forest tree species to optimize the management and sustainable use of forest genetic resources. Our dataset captures substantial intra‐ and interspecific leaf phenotypic variability, and provides valuable information for studying the relationship between ecosystem functioning and trait variability of individuals, and the response and resilience of species to environmental changes. Main types of variable contained: We chose morphological and chemical characters linked to trade‐offs between acquisition and conservation of resources and water use, namely specific leaf area, leaf size, carbon and nitrogen content and their ratio, and the isotopic signature of stable isotope ¹³C and ¹⁵N in leaves. Spatial location and grain: We surveyed between 18 and 22 populations per species, 141 in total, across Europe. Time period: Leaf sampling took place between 2016 and 2017. Major taxa and level of measurement: We sampled at least 25 individuals in each population, 3,569 trees in total, and measured traits in 35,755 leaves from seven European tree species, i.e. the conifers Picea abies, Pinus pinaster and Pinus sylvestris, and the broadleaves Betula pendula, Fagus sylvatica, Populus nigra and Quercus petraea. Software format: The data files are in ASCII text, tab delimited, not compressed.
- Published
- 2021
19. Febrile young infants with abnormal urine dipstick at low risk of invasive bacterial infection
- Author
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Velasco R, Lejarzegi A, Gomez B, de la Torre M, Duran I, Camara A, de la Rosa D, Manzano S, Rodriguez J, González A, Lopes AA, Rivas A, Martinez I, Angelats CM, Moya S, Corral S, Alonso J, Del Rio P, Sancho E, Ruiz Del Olmo I, Nieto I, Vega B, Mintegi S, and Research in European Pediatric Emergency Medicine (REPEM) and the Spanish Pediat
- Abstract
Objectives To develop and validate a prediction rule to identify well-appearing febrile infants aged = 0.6 ng/mL) and C reactive protein (>= 20 mg/L) as risk factors. The absence of any risk factor had a sensitivity of 96.0% (95% CI 80.5% to 99.3%), a negative predictive value of 99.4% (95% CI 96.4% to 99.9%) and a specificity of 32.9% (95% CI 28.8% to 37.3%) for ruling out an IBI. Applying it in the 449 infants of the validation set (IBI rate 4.9%), sensitivity, negative predictive value and specificity were 100% (95% CI 87.1% to 100%), 100% (95% CI 97.3% to 100%) and 29.7% (95% CI 25.8% to 33.8%), respectively. Conclusion This prediction rule accurately identified well-appearing febrile infants aged
- Published
- 2021
20. New alternatives to conventional Internal Medicine
- Author
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Miranda Sancho, E., Bianchi Llave, J. L., and Prieto Vicente, A.
- Abstract
El aumento de la prevalencia de las enfermedades crónicas asociado al envejecimiento de la población es uno de los desafíos más importantes a los que se enfrentan los sistemas de salud en el mundo. Se está produciendo un cambio en los motivos de ingresos hospitalarios, con un alto porcentaje de ellos por motivos diagnósticos mas que terapéuticos, en parte por la presión asistencial a la que se está sometiendo a los dispositivos asistenciales ambulatorios, con generación de importantes listas de espera para estudio.
- Published
- 2021
21. Corneal Biomechanical Parameters and Central Corneal Thickness in Glaucoma Patients, Glaucoma Suspects, and a Healthy Population
- Author
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Del Buey-Sayas MÁ, Lanchares-Sancho E, Campins-Falcó P, Pinazo-Durán MD, and Peris-Martínez C
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glaucoma ,ocular inflammation ,corneal hysteresis ,ocular biomarkers ,corneal biomechanics - Abstract
Purpose: To evaluate and compare corneal hysteresis (CH), corneal resistance factor (CRF), and central corneal thickness (CCT), measurements were taken between a healthy population (controls), patients diagnosed with glaucoma (DG), and glaucoma suspect patients due to ocular hypertension (OHT), family history of glaucoma (FHG), or glaucoma-like optic discs (GLD). Additionally, Goldmann-correlated intraocular pressure (IOPg) and corneal-compensated IOP (IOPcc) were compared between the different groups of patients. Methods: In this prospective analytical-observational study, a total of 1065 patients (one eye of each) were recruited to undergo Ocular Response Analyzer (ORA) testing, ultrasound pachymetry, and clinical examination. Corneal biomechanical parameters (CH, CRF), CCT, IOPg, and IOPcc were measured in the control group (n = 574) and the other groups: DG (n = 147), FHG (n = 78), GLD (n = 90), and OHT (n = 176). We performed a variance analysis (ANOVA) for all the dependent variables according to the different diagnostic categories with multiple comparisons to identify the differences between the diagnostic categories, deeming p < 0.05 as statistically significant. Results: The mean CH in the DG group (9.69 mmHg) was significantly lower compared to controls (10.75 mmHg; mean difference 1.05, p < 0.001), FHG (10.70 mmHg; mean difference 1.00, p < 0.05), GLD (10.63 mmHg; mean difference 0.93, p < 0.05) and OHT (10.54 mmHg; mean difference 0.84, p < 0.05). No glaucoma suspects (FHG, GLD, OHT groups) presented significant differences between themselves and the control group (p = 1.00). No statistically significant differences were found in the mean CRF between DG (11.18 mmHg) and the control group (10.75 mmHg; mean difference 0.42, p = 0.40). The FHG and OHT groups showed significantly higher mean CRF values (12.32 and 12.41 mmHg, respectively) than the DG group (11.18 mmHg), with mean differences of 1.13 (p < 0.05) and 1.22 (p < 0.001), respectively. No statistically significant differences were found in CCT in the analysis between DG (562 mu) and the other groups (control = 556 mu, FHG = 576 mu, GLD = 569 mu, OHT = 570 mu). The means of IOPg and IOPcc values were higher in the DG patient and suspect groups than in the control group, with statistically significant differences in all groups (p < 0.001). Conclusion: This study presents corneal biomechanical values (CH, CRF), CCT, IOPg, and IOPcc for diagnosed glaucoma patients, three suspected glaucoma groups, and a healthy population, using the ORA. Mean CH values were markedly lower in the DG group (diagnosed with glaucoma damage) compared to the other groups. No significant difference was found in CCT between the DG and control groups. Unexpectedly, CRF showed higher values in all groups than in the control group, but the difference was only statistically significant in the suspect groups (FHG, GLD, and OHT), not in the DG group.
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- 2021
22. The GenTree Platform:growth traits and tree-level environmental data in 12 European forest tree species
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Opgenoorth, L. (Lars), Benjamin, D. (Dauphin), Benavides, R. (Raquel), Heer, K. (Katrin), Alizoti, P. (Paraskevi), Martinez-Sancho, E. (Elisabet), Alia, R. (Ricardo), Ambrosio, O. (Olivier), Audrey, A. (Albet), Aunon, F. (Francisco), Avanzi, C. (Camilla), Avramidou, E. (Evangelia), Bagnoli, F. (Francesca), Barbas, E. (Evangelos), Bastias, C. C. (Cristina C.), Bastien, C. (Catherine), Ballesteros, E. (Eduardo), Beffa, G. (Giorgia), Bernier, F. (Frederic), Bignalet, H. (Henri), Bodineau, G. (Guillaume), Bouic, D. (Damien), Brodbeck, S. (Sabine), Brunetto, W. (William), Buchovska, J. (Jurata), Buy, M. (Melanie), Cabanillas-Saldana, A. M. (Ana M.), Carvalho, B. (Barbara), Cheval, N. (Nicolas), Climent, J. M. (Jose M.), Correard, M. (Marianne), Cremer, E. (Eva), Danusevicius, D. (Darius), Del Cano, F. (Fernando), Denou, J.-L. (Jean-Luc), di Gerardi, N. (Nicolas), Dokhelar, B. (Bernard), Ducousso, A. (Alexis), Nilsen, A. E. (Anne Eskild), Farsakoglou, A.-M. (Anna-Maria), Fonti, P. (Patrick), Ganopoulos, I. (Ioannis), Garcia del Barrio, J. M. (Jose M.), Gilg, O. (Olivier), Gonzalez-Martinez, S. C. (Santiago C.), Graf, R. (Rene), Gray, A. (Alan), Grivet, D. (Delphine), Gugerli, F. (Felix), Hartleitner, C. (Christoph), Hollenbach, E. (Enja), Hurel, A. (Agathe), Issehut, B. (Bernard), Jean, F. (Florence), Jorge, V. (Veronique), Jouineau, A. (Arnaud), Kappner, J.-P. (Jan-Philipp), Karkkainen, K. (Katri), Kesälahti, R. (Robert), Knutzen, F. (Florian), Kujala, S. T. (Sonja T.), Kumpula, T. A. (Timo A.), Labriola, M. (Mariaceleste), Lalanne, C. (Celine), Lambertz, J. (Johannes), Lascoux, M. (Martin), Lejeune, V. (Vincent), Le-Provost, G. (Gregoire), Levillain, J. (Joseph), Liesebach, M. (Mirko), Lopez-Quiroga, D. (David), Meier, B. (Benjamin), Malliarou, E. (Ermioni), Marchon, J. (Jeremy), Mariotte, N. (Nicolas), Mas, A. (Antonio), Matesanz, S. (Silvia), Meischner, H. (Helge), Michotey, C. (Celia), Milesi, P. (Pascal), Morganti, S. (Sandro), Nievergelt, D. (Daniel), Notivol, E. (Eduardo), Ostreng, G. (Geir), Pakull, B. (Birte), Perry, A. (Annika), Piotti, A. (Andrea), Plomion, C. (Christophe), Poinot, N. (Nicolas), Pringarbe, M. (Mehdi), Puzos, L. (Luc), Pyhajarvi, T. (Tanja), Raffin, A. (Annie), Ramirez-Valiente, J. A. (Jose A.), Rellstab, C. (Christian), Remi, D. (Dourthe), Richter, S. (Sebastian), Robledo-Arnuncio, J. J. (Juan J.), San Segundo, S. (Sergio), Savolainen, O. (Outi), Schueler, S. (Silvio), Schneck, V. (Volker), Scotti, I. (Ivan), Semerikov, V. (Vladimir), Slamova, L. (Lenka), Sonstebo, J. H. (Jorn Henrik), Spanu, I. (Ilaria), Thevenet, J. (Jean), Tollefsrud, M. M. (Mari Mette), Turion, N. (Norbert), Vendramin, G. G. (Giovanni Giuseppe), Villar, M. (Marc), von Arx, G. (Georg), Westin, J. (Johan), Fady, B. (Bruno), Myking, T. (Tor), Valladares, F. (Fernando), Aravanopoulos, F. A. (Filippos A.), and Cavers, S. (Stephen)
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crown size ,fruit number ,bark thickness ,DBH ,regeneration ,branch angle ,soil depth ,forking index ,stem straightness ,height - Abstract
Background: Progress in the field of evolutionary forest ecology has been hampered by the huge challenge of phenotyping trees across their ranges in their natural environments, and the limitation in high-resolution environmental information. Findings: The GenTree Platform contains phenotypic and environmental data from 4,959 trees from 12 ecologically and economically important European forest tree species: Abies alba Mill. (silver fir), Betula pendula Roth. (silver birch), Fagus sylvatica L. (European beech), Picea abies (L.) H. Karst (Norway spruce), Pinus cembra L. (Swiss stone pine), Pinus halepensis Mill. (Aleppo pine), Pinus nigra Arnold (European black pine), Pinus pinaster Aiton (maritime pine), Pinus sylvestris L. (Scots pine), Populus nigra L. (European black poplar), Taxus baccata L. (English yew), and Quercus petraea (Matt.) Liebl. (sessile oak). Phenotypic (height, diameter at breast height, crown size, bark thickness, biomass, straightness, forking, branch angle, fructification), regeneration, environmental in situ measurements (soil depth, vegetation cover, competition indices), and environmental modeling data extracted by using bilinear interpolation accounting for surrounding conditions of each tree (precipitation, temperature, insolation, drought indices) were obtained from trees in 194 sites covering the species’ geographic ranges and reflecting local environmental gradients. Conclusions: The GenTree Platform is a new resource for investigating ecological and evolutionary processes in forest trees. The coherent phenotyping and environmental characterization across 12 species in their European ranges allow for a wide range of analyses from forest ecologists, conservationists, and macro-ecologists. Also, the data here presented can be linked to the GenTree Dendroecological collection, the GenTree Leaf Trait collection, and the GenTree Genomic collection presented elsewhere, which together build the largest evolutionary forest ecology data collection available.
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- 2021
23. Studies of the temperature coefficient of capacitance (TCC) of a new electroceramic composite: Pb(Fe0.5Nb0.5)O3 (PFN)–Cr0.75Fe1.25O3(CRFO)
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Freire, F. N. A., Santos, M. R. P., Pereira, F. M. M., Sohn, R. S. T. M., Almeida, J. S., Medeiros, A. M. L., Sancho, E. O., Costa, M. M., and Sombra, A. S. B.
- Published
- 2009
- Full Text
- View/download PDF
24. Poster abstracts
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Ferrie, J., Shipley, M., Cappuccio, F., Brunner, E., Miller, M., Kumari, M., Marmot, M., Coenen, A., Castillo, J. L., Araya, F., Bustamante, G., Montecino, L., Torres, C., Oporto, S., Gronli, J., Fiske, E., Murison, R., Bjorvatn, B., Sorensen, E., Ursin, R., Portas, C. M., Rajaraman, S., Gribok, A., Wesensten, N., Balkin, T., Reifman, J., Dursunoglu, N., Ozkurt, S., Baser, S., Delen, O., Sarikaya, S., Sadler, P., Mitchell, P., Françon, D., Decobert, M., Herve, B., Richard, A., Griebel, G., Avenet, P., Scatton, B., Fur, G. L., Eckert, D., Jordan, A., Wellman, A., Smith, S., Malhotra, A., White, D., Bruck, D., Thomas, I., Kritikos, A., Oertel, W., Stiasny-Kolster, K., Garcia-Borreguero, D., Poewe, W., Hoegl, B., Kohnen, R., Schollmayer, E., Keffel, J., Trenkwalder, C., Valle, A., Roizenblatt, S., Fregni, F., Boggio, P., Tufik, S., Ward, K., Robertson, L., Palmer, L., Eastwood, P., Hillman, D., Lee, J., Mukherjee, S., de Padova, V., Barbato, G., Ficca, G., Zilli, I., Salzarulo, P., Veldi, M., Hion, T., Vasar, V., Kull, M., Nowak, L., Davis, J., Latzer, Y., Tzischinsky, O., Crowley, S., Carskadon, M., Anca-Herschkovitsch, M., Frey, D., Ortega, J., Wiseman, C., Farley, C., Wright, K., Campbell, A., Neill, A., Spiegel, K., Leproult, R., Tasali, E., Scherberg, N., van Cauter, E., Noradina, A. T., Karim, N. A., Norlinah, I., Raymond, A. A., Sahathevan, R., Hamidon, B., Werth, E., Poryazova, R., Khatami, R., Bassetti, C., Beran, R. G., Ainley, L., Holand, G., Duncan, J., Kinney, H., Davis, B., Hood, B., Frey, S., Schmidt, C., Hofstetter, M., Peigneux, P., Cajochen, C., Hu, W.-P., Li, J.-D., Zhang, C., Boehmer, L., Siegel, J., Zhou, Q.-Y., Sagawa, Y., Kondo, H., Takemura, T., Kanayama, H., Kaneko, Y., Sato, M., Kanbayashi, T., Hishikawa, Y., Shimizu, T., Viola, A., James, L., Schlangen, L., Dijk, D.-J., Andretic, R., Kim, Y.-C., Han, K.-A., Jones, F., Greenspan, R., Sanford, L., Yang, L., Tang, X., Dieter, K., Uta, E., Sven, H., Richard, M., Oyane, N., Pallesen, S., Holsten, F., Inoue, Y., Fujita, M., Emura, N., Kuroda, K., Uchimura, N., Johnston, A., Astbury, J., Kennedy, G., Hoedlmoser, K., Schabus, M., Pecherstorfer, T., Moser, S., Gruber, G., Anderer, P., Klimesch, W., Naidoo, N., Ferber, M., Pack, A., Neu, D., Mairesse, O., Hoffmann, G., Dris, A., Lambrecht, L., Linkowski, P., Verbanck, P., Le Bon, O., Matsuura, N., Yamao, M., Adachi, N., Aritomi, R., Komada, Y., Tanaka, H., Shirakawa, S., Kondoh, H., Takemura, F., Ohnuma, S., Suzuki, M., Uemura, S., Iskra-Golec, I., Smith, L., Thanh, D.-V., Boly, M., Phillips, C., Steven, L., Luxen, A., Maquet, M., Jay, S., Dawson, D., Lamond, N., Basner, M., Fomberstein, K., Dinges, D., Ogawa, K., Nittono, H., Yamazaki, K., Hori, T., Glamann, C., Hornung, O., Hansen, M.-L, Danker-Hopfe, H., Jung, C., Kecklund, G., Anund, A., Peters, B., Åkerstedt, T., Verster, J., Roehrs, T., Mets, M., de Senerpont Domis, L., Olivier, B., Volkerts, E., Knutson, K., Lauderdale, D., Rathouz, P., Christie, M., Chen, L., Bolortuya, Y., Lee, E., Mckenna, J., Mccarley, R., Strecker, R., Tamaki, M., Matsuoka, T., Aritake, S., Suzuki, H., Kuriyama, K., Ozaki, A., Abe, Y., Enomoto, M., Tagaya, H., Mishima, K., Matsuura, M., Uchiyama, M., Lima-Pacheco, E., Davis, K., Sabourin, C., Lortie-Lussier, M., de Koninck, J., van Der Werf, Y., van Der Helm, E., Schoonheim, M., van Someren, E., Tokley, M., Ball, M., Sato, T., Ghilardi, M. F., Moisello, C., Bove, M., Busi, M., Pelosin, E., Tononi, G., Eguchi, N., Sakata, M., Urade, Y., Doe, N., Yoshihara, K., Abe, K., Manabe, Y., Iwatsuki, K., Hayashi, T., Shoji, M., Kamiya, T., Gooley, J., Brainard, G., Rajaratnam, S., Kronauer, R., Czeisler, C., Lockley, S., Phillips, A., Robinson, P., Burgess, H., Revell, V., Eastman, C., Bihari, S., Ramakrishnan, N., Camerino, D., Conway, P. M., Costa, G., Vandewalle, G., Albouy, G., Sterpenich, V., Darsaud, A., Rauchs, G., Berken, P.-Y, Balteau, E., Maquet, P., Tendero, J. A., Domenech, M. P., Isern, F. S., Martínez, C., Roure, N., Sancho, E. E., Moreno, C. R., Silva, M., Marqueze, E. C., Waage, S., Bobko, N., Chernyuk, V., Yavorskiy, Y., Saxvig, I., Sørensen, E., de Mello, M. T., Esteves, A., Teixeira, C., Bittencourt, L. R., Silva, R., Pires, M. L., Mottram, V., Middelton, B., Arendt, J., Amaral, O., Rodrigues, M., Pereira, C., Tavares, I., Baba, K., Honma, S., Honma, K.-I., Yamanaka, Y., Hashimoto, S., Tanahashi, Y., Nishide, S.-Y, Honma, K.-I, Sletten, T., Middleton, B., Lederle, K., Skene, D., Roth, T., Walsh, J., Hogben, A., Ellis, J., Archer, S., von Schantz, M., Chen, N.-H., Wang, P.-C., Chen, C.-W., Lin, Y., Shih, T.-S., Armstrong, S., Redman, J., Stephan, E., David, M., Delanaud, S., Chardon, K., Libert, J.-P., Bach, V., Telliez, F., Reid, K., Jaksa, A., Eisengart, J., Kane, P., Naylor, E., Zee, P., Viola, A. U., de Valck, E., Hofmans, J., Theuns, P., Cluydts, R., Alexander, G., Karel, M., Christina, R., Sohn, I.-K., Cho, I. H., Kim, S. J., Yu, S.-H., Kim, H., Yoo, S. Y., Koh, S.-H., Cho, S.-J., Rotenberg, L., Silva-Costa, A., Griep, R. H., Amely, T., Kennedy, G. A., Pavlis, A., Thompson, B., Pierce, R., Howard, M., Briellmann, R., Venkateswaran, S., Blunden, S., Krawczyk, E., Blake, J., Gururajan, R., Kerr, D., Matuisi, T., Iwasaki, M., Yamasita, N., Iemura, A., Ohya, T., Yanagawa, T., Misa, R., Coleman, G., Conduit, R., Duce, B., Hukins, C., Nyandaiti, Y. W., Bamaki, S., Mohammed, A., Kwajarfa, S., Veeramachaneni, S. P., Murthy, A., Wilson, A., Maul, J., Hall, G., Stick, S., Moseley, L., Gradisar, M., Kurihara, T., Yamamoto, M., Yamamoto, S., Kuranari, M., Sparks, C. B., Bartle, A., Beckert, L., Latham-Smith, F. B., Hilton, J., Whitehead, B., Gulliver, T., Salvini, A., Grahame, S., Swift, M., Laybutt, N., Sharon, D., Mack, C., Hymell, B., Perrine, B., Ideshita, K., Taira, M., Matuo, A., Furutani, M., van Dongen, H., Mott, C., Huang, J.-K., Mollicone, D. J., Mckenzie, F., Dinges, David, Barnes, M., Rochford, P., Churchward, T., O’Donoghue, F., Penzel, T., Fietze, I., Canisius, S., Bekiaris, E., Terrill, P. I., Wilson, S., Suresh, S., Cooper, D., Suzuki, T., Ouchi, K., Moriya, A., Kameyama, K., Takahashi, M., Büttner, A., Rühle, K.-H., Wang, D., Wong, K., Dungan, II, G., Grunstein, R., Davidson, P., Jones, R., Gergely, V., Mashima, K., Miyazaki, S., Tanaka, T., Okawa, M., Yamada, N., Wyner, A., Raizen, D., Galante, R., Ng, A. K., Koh, T. S., Lim, L. L., Puvanendran, K., Peiris, M., Bones, P., Roebuck, T., Ho, S., Szollosi, I., Naughton, M., Williams, G., Parsley, C., Harris, M.-A., Thornton, A., Ruehland, W., Banks, S., Arroyo, S., Carroll, K., Pilmore, J., Stewart, C., Hamilton, G., van Acker, F., Cvetkovic, D., Holland, G., Cosic, I., Tolson, J., Worsnop, C., Cresswell, P., Hart, I., Bouarab, M., Delechelle, E., Drouot, X., Acebo, C., Singh, P., Lakey, T., Schachter, L., Rand, J., Collin, H., Snyder, E., Ma, J., Svetnick, V., Deacon, S., Dana, B., Konstanze, D., Uwe, M., Ingo, F., Thomas, P., Ivar, R., Mackiewicz, M., Shockley, K., Romer, M., Zimmerman, J., Baldwin, D., Jensen, S., Churchill, G., Paigen, B., Imeri, L., Ferrari, L., Bianchi, S., Dossena, S., Garofoli, A., Mangieri, M., Tagliavini, F., Forloni, G., Chiesa, R., Pedrazzoli, M., Pereira, D., Veauny, M., Bodenmann, S., Hohoff, C., Freitag, C., Deckert, J., Rétey, J., Landolt, H.-P., Strohl, K., Price, E., Yamauchi, M., Dostal, J., Feng, P., Han, F., Havekes, R., Novati, A., Hagewoud, R., Barf, P., van Der Borght, K., van Der Zee, E., Meerlo, P., Ruby, P., Caclin, A., Boulet, S., Delpuech, C., Morlet, D., Veasey, S., Aton, S., Jha, S., Coleman, T., Seibt, J., Frank, M., Lack, L., Churches, O., Feng, S. Y. S., Cassaglia, P., Yu, V. Y. H., Walker, A. M., Kohler, M., Kennedy, D., Martin, J., van Den Heuvel, C., Lushington, K., Herron, K., Khurana, C., Sterr, A., Olivadoti, M., Toth, L., Opp, M., Dang-Vu, T., Degueldre, C., Gais, S., Dang-Vu, T. T., Desseilles, M., Philips, C., Chijavadze, E., Babilodze, M., Chkhartishvili, E., Nachkebia, N., Mchedlidze, O., Dzadzamia, S., Griffiths, R., Walker, A., Horovitz, S., Fukunaga, M., Carr, W., Picchioni, D., de Zwart, J., van Gelderen, P., Braun, A., Duyn, J., Hanlon, E. H., Faraguna, U., Vyazovskiy, V., Cirelli, C., Ocampo-Garcés, A., Ibáñez, F., López, S., Vivaldi, E., Torrealba, F., Romanowski, C. P. N., Fenzl, T., Flachskamm, C., Deussing, J., Kimura, M., Tarokh, L., van Reen, E., Dorn, H., Velluti, R., Qu, W.-M., Huang, Z.-L., Hayaishi, O., Pedemonte, M., Drexler, D., Pol-Fernández, D., Bernhardt, V., Lopez, C., Rodriguez-Servetti, Z., Romanowski, C., Polta, S., Yassouridis, A., Abe, T., Takahashi, K., Koyama, Y., Kayama, Y., Lin, J.-S., Sakai, K., Gulia, K., Karashima, A., Shimazaki, M., Katayama, N., Nakao, M., Winsky-Sommerer, R., Knapman, A., Tobler, I., Altena, E., Sanz-Arigita, E., Chang, F.-C., Lu, C.-Y., Yi, P.-L., Hsiao, Y.-Z., Lowden, A., Nilsson, J., Hillert, L., Wiholm, C., Kuster, N., Arnetz, B., Szameitat, A., Shen, S., Daurat, A., Tiberge, M., Sok, N., D’Ortho, M. P. I. A., Karasinsky, P., Kohlmeier, K., Wess, J., Leonard, C., Kristensen, M., Kalinchuk, A., Porkka-Heiskanen, T., Mccarley, R. W., Basheer, R., Aizawa, R., Sunahara, H., Abe, S.-I., Iwaki, S., Houjyou, M., Satoh, M., Suda, H., Kheirandish-Gozal, L., Gozal, D., Walker, P., Noa, A., O’Driscoll, D., Ng, M., Yang, J., Davey, M., Anderson, V., Trinder, J., Horne, R., Sands, S., Kelly, V., Sia, K., Edwards, B., Skuza, E., Davidson, M., Berger, P. H. I. L. I. P., Wilkinson, M., Sánchez-Narváez, F., Gutiérrez, R., Camacho, L., Anaya, E., García-Campos, E., Labra, A., Domínguez, G., García-Polo, L., Haro, R., Verginis, N., Nixon, G., Baumert, M., Pamula, Y., Mihai, R., Wawurszak, M., Smith, N., Yiallourou, S., Andrew Ramsden, C., Williamson, B., Blecher, G., Teng, A., Dakin, C. Y. N., Yuil, M., Harris, M., Sadasivam, S., Bennison, J., Galland, B., Dawes, P., Taylor, B., Norman, M., Edwards, N., Harrison, H., Kol, C., Sullivan, C., Valladares, E., Macey, P., Kumar, R., Woo, M., Harper, R., Alger, J., Mcnamara, D., Tang, J., Goh, A., Teoh, O. H., Chiang, W. C., Chay, O. M., Marie Salvini, A., Riben, C., Blanck, A.-S., Marklund, M., Tourneux, P., Cardot, V., Leke, A., Iqbal, S. M., (Gus) Cooper, D., Witmans, M., Rodger, K., Thevasagayam, R., El-Hakim, H., Hill, C. M., Baya, A., Bucks, R., Kirkham, F., Virues-Ortega, J., Baldeweg, T., Paul, A., Hogan, A., Goodwin, J., Silva, G., Kaemingk, K., Sherrill, D., Morgan, W., Fregosi, R., Quan, S., Evans, C., Maclean, J., Waters, K., Fitzsimmons, D., Hayward, P., Fitzgerald, D., Terrill, G., O’Connell, A., Vannan, K., Richardson, H., Poluektov, M., Levin, I., Snegodskaya, M., Kolosova, N., Geppe, N., Nixon, G. Michelle, Thompson, J., Yhan, D., Becroft, D., Clark, P., Robinson, E., Waldie, K., Wild, C., Black, P., Stone, K., Britton, W., Chaves, Claudia, Tinoco, C., Goncalves, C., Ferreira, E., Santos, H., Boloto, J., Duarte, L., Paine, S., Wright, H., Slater, A., Rosen, G., Telliez, Frédéric, Djeddi, D., Kongolo, G., Degrugilliers, L., Horton, J., Buscemi, N., Vandermeer, B., Owens, J., Klassen, T., Gordon, J., King, N., Tripp, G., Oka, Y., Suzuki, S., de Lemos, M. C., Gonzaga, F. G., Shah, M. L., Bittencourt, L., Oliveira, L. V. Franco, Elshoff, J.-P., Braun, M., Andreas, J.-O., Strauss, B., Horstmann, R., Ahrweiler, S., Goldammer, N., Wada, M., Matsumoto, N., Rahman, M. D., Xu, X.-H., Makino, Y., Hashimoto, K., Zhang, M., Sastre, J.-P., Buda, C., Anaclet, C., Ohtsu, H., Danober, L., Desos, P., Cordi, A., Roger, A., Jacquet, A., Rogez, N., Thomas, J.-Y., Krentner, M., Boutin, J., Audinot-Bouchez, V., Baumann, C., Valko, P., Uhl, M., Hersberger, M., Rupp, T., Uchiyama, N., Nakamura, N., Konishi, T., Mcgrath, P., Fujiki, N., Tokunaga, J., Iijima, S., Nishino, S., Catherine, B.-R., Lely, F., Ralf, K., Oliver, N., François, J., Francois, J., Cedric, F., Changbin, Q., Patrick, H., Homanics, G., Heussler, H., Norris, R., Pache, D., Charles, B., Mcguire, T., Shelton, J., Bonaventure, P., Kelly, L., Aluisio, L., Lovenberg, T., Atack, J., Dugovic, C., Shapiro, C., Shen, J., Trajanovic, N., Chien, J., Verma, M., Fish, V., Wheatley, J., Amis, T., Alexiou, T., Wild, J., Bjursell, A., Solin, P., Sato, S., Matsubuchi, N., Gingras, M.-A., Labrosse, M., Chevrier, É, Lageix, P., Guay, M.-C., Braun, C., Godbout, R., Fatim, E. 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Y., Serber, S. T. A. C. Y., Valladares, E. D. W. I. N., Harper, R. E. B. E. C. C. A., Harper, R. O. N. A. L. D., Puttonen, S., Härmä, M., Vahtera, J., Kivimäki, M., Lamarche, L., Hemmeter, U. M., Thum, A., Rocamora, R., Giesler, M., Haag, A., Dodel, R., Krieg, J. C., Shechter, A., L’Esperance, P., Boivin, D. B., Vu, M.-T., and Richards, H.
- Published
- 2007
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25. The GenTree Dendroecological Collection, tree-ring and wood density data from seven tree species across Europe
- Author
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Martínez-Sancho, E. (Elisabet), Slámová, L. (Lenka), Morganti, S. (Sandro), Grefen, C. (Claudio), Carvalho, B. (Barbara), Dauphin, B. (Benjamin), Rellstab, C. (Christian), Gugerli, F. (Felix), Opgenoorth, L. (Lars), Heer, K. (Katrin), Knutzen, F. (Florian), von Arx, G. (Georg), Valladares, F. (Fernando), Cavers, S. (Stephen), Fady, B. (Bruno), Alía, R. (Ricardo), Aravanopoulos, F. (Filippos), Avanzi, C. (Camilla), Bagnoli, F. (Francesca), Barbas, E. (Evangelos), Bastien, C. (Catherine), Benavides, R. (Raquel), Bernier, F. (Frédéric), Bodineau, G. (Guillaume), Bastias, C. C. (Cristina C.), Charpentier, J.-P. (Jean-Paul), Climent, J. M. (José M.), Corréard, M. (Marianne), Courdier, F. (Florence), Danusevicius, D. (Darius), Farsakoglou, A.-M. (Anna-Maria), García del Barrio, J. M. (José M.), Gilg, O. (Olivier), González-Martínez, S. C. (Santiago C.), Gray, A. (Alan), Hartleitner, C. (Christoph), Hurel, A. (Agathe), Jouineau, A. (Arnaud), Kärkkäinen, K. (Katri), Kujala, S. T. (Sonja T.), Labriola, M. (Mariaceleste), Lascoux, M. (Martin), Lefebvre, M. (Marlène), Lejeune, V. (Vincent), Le-Provost, G. (Grégoire), Liesebach, M. (Mirko), Malliarou, E. (Ermioni), Mariotte, N. (Nicolas), Matesanz, S. (Silvia), Michotey, C. (Célia), Milesi, P. (Pascal), Myking, T. (Tor), Notivol, E. (Eduardo), Pakull, B. (Birte), Piotti, A. (Andrea), Plomion, C. (Christophe), Pringarbe, M. (Mehdi), Pyhäjärvi, T. (Tanja), Raffin, A. (Annie), Ramírez-Valiente, J. A. (José A.), Ramskogler, K. (Kurt), Robledo-Arnuncio, J. J. (Juan J.), Savolainen, O. (Outi), Schueler, S. (Silvio), Semerikov, V. (Vladimir), Spanu, I. (Ilaria), Thévenet, J. (Jean), Tollefsrud, M. M. (Mari Mette), Turion, N. (Norbert), Veisse, D. (Dominique), Vendramin, G. G. (Giovanni Giuseppe), Villar, M. (Marc), Westin, J. (Johan), Fonti, P. (Patrick), Martínez-Sancho, E. (Elisabet), Slámová, L. (Lenka), Morganti, S. (Sandro), Grefen, C. (Claudio), Carvalho, B. (Barbara), Dauphin, B. (Benjamin), Rellstab, C. (Christian), Gugerli, F. (Felix), Opgenoorth, L. (Lars), Heer, K. (Katrin), Knutzen, F. (Florian), von Arx, G. (Georg), Valladares, F. (Fernando), Cavers, S. (Stephen), Fady, B. (Bruno), Alía, R. (Ricardo), Aravanopoulos, F. (Filippos), Avanzi, C. (Camilla), Bagnoli, F. (Francesca), Barbas, E. (Evangelos), Bastien, C. (Catherine), Benavides, R. (Raquel), Bernier, F. (Frédéric), Bodineau, G. (Guillaume), Bastias, C. C. (Cristina C.), Charpentier, J.-P. (Jean-Paul), Climent, J. M. (José M.), Corréard, M. (Marianne), Courdier, F. (Florence), Danusevicius, D. (Darius), Farsakoglou, A.-M. (Anna-Maria), García del Barrio, J. M. (José M.), Gilg, O. (Olivier), González-Martínez, S. C. (Santiago C.), Gray, A. (Alan), Hartleitner, C. (Christoph), Hurel, A. (Agathe), Jouineau, A. (Arnaud), Kärkkäinen, K. (Katri), Kujala, S. T. (Sonja T.), Labriola, M. (Mariaceleste), Lascoux, M. (Martin), Lefebvre, M. (Marlène), Lejeune, V. (Vincent), Le-Provost, G. (Grégoire), Liesebach, M. (Mirko), Malliarou, E. (Ermioni), Mariotte, N. (Nicolas), Matesanz, S. (Silvia), Michotey, C. (Célia), Milesi, P. (Pascal), Myking, T. (Tor), Notivol, E. (Eduardo), Pakull, B. (Birte), Piotti, A. (Andrea), Plomion, C. (Christophe), Pringarbe, M. (Mehdi), Pyhäjärvi, T. (Tanja), Raffin, A. (Annie), Ramírez-Valiente, J. A. (José A.), Ramskogler, K. (Kurt), Robledo-Arnuncio, J. J. (Juan J.), Savolainen, O. (Outi), Schueler, S. (Silvio), Semerikov, V. (Vladimir), Spanu, I. (Ilaria), Thévenet, J. (Jean), Tollefsrud, M. M. (Mari Mette), Turion, N. (Norbert), Veisse, D. (Dominique), Vendramin, G. G. (Giovanni Giuseppe), Villar, M. (Marc), Westin, J. (Johan), and Fonti, P. (Patrick)
- Abstract
The dataset presented here was collected by the GenTree project (EU-Horizon 2020), which aims to improve the use of forest genetic resources across Europe by better understanding how trees adapt to their local environment. This dataset of individual tree-core characteristics including ring-width series and whole-core wood density was collected for seven ecologically and economically important European tree species: silver birch (Betula pendula), European beech (Fagus sylvatica), Norway spruce (Picea abies), European black poplar (Populus nigra), maritime pine (Pinus pinaster), Scots pine (Pinus sylvestris), and sessile oak (Quercus petraea). Tree-ring width measurements were obtained from 3600 trees in 142 populations and whole-core wood density was measured for 3098 trees in 125 populations. This dataset covers most of the geographical and climatic range occupied by the selected species. The potential use of it will be highly valuable for assessing ecological and evolutionary responses to environmental conditions as well as for model development and parameterization, to predict adaptability under climate change scenarios.
- Published
- 2020
26. New alternatives to conventional Internal Medicine
- Author
-
Miranda-Sancho, E., primary, Bianchi-Llave, J.L., additional, and Prieto-Vicente, A., additional
- Published
- 2021
- Full Text
- View/download PDF
27. Comparative Study of the Toxicity of Molinate for Freshwater Organisms
- Author
-
Sancho, E., Sanchez, M., Ferrando, M. D., and Andreu-Moliner, E.
- Published
- 2003
- Full Text
- View/download PDF
28. Effect of an Acaricide on the Reproduction and Survival of Daphnia magna
- Author
-
Villarroel, M. J., Sancho, E., Ferrando, M. D., and Andreu-Moliner, E.
- Published
- 1999
- Full Text
- View/download PDF
29. Dielectric characterisation and numerical investigation of SrBi2Nb2O9–Bi2O3 composites for applications in microwave range
- Author
-
Abreu, R. F., primary, Saturno, S. O., additional, do Nascimento, J. P. C., additional, Sancho, E. O., additional, de Morais, J. E. V., additional, Sales, J. C., additional, Gouveia, D. X., additional, de Andrade, H. D., additional, Queiroz Júnior, I. S., additional, and Sombra, A. S. B., additional
- Published
- 2020
- Full Text
- View/download PDF
30. Sublethal Bioconcentration of Fenitrothion in the Blood and Brain of the European Eel
- Author
-
Sancho, E., Ferrando, M. D., Ten, A., Lleó, C., and Andreu-Moliner, E.
- Published
- 1998
- Full Text
- View/download PDF
31. Effectiveness of Lenalidomide in Patients with Relapsed or Progressive Multiple Myeloma: A114
- Author
-
Amor, A A, Casanova, M, Fuertes, M, Guzmán, J L, Bueno, B A, Giraldo, P, Cánovas, A, Ibáñez, A, Castillo, I, Blanes, M, Ríos, E, Rodríguez, J N, Palomera, L, Hernández, M T, Oriol, A, Sancho, E, Menchaca, C, Vercher, J, González, A P, Arilla, M J, Ramírez, G, Pérez, R, Asensio, A, de la Serna, J, Osorio, S, Aguilar, C, Ansó, V, Calvo, J M, López, L, López, A, Olalla, J I, Hernández, J M, Petit, J, Ríos, P, Villalón, L, García, I, García, A, Larregla, S, García-Escribano, F L, and Lahuerta, J J
- Published
- 2009
32. Accumulation of Tetradifon in an Algae (Nannochloris oculata) and the Cladoceran, Daphnia magna
- Author
-
Ferrando, M. D., Sancho, E., and Andreu-Moliner, E.
- Published
- 1996
- Full Text
- View/download PDF
33. Bioconcentration and excretion of diazinon by eel
- Author
-
Sancho, E., Ferrando, M. D., Andreu, E., and Gamon, M.
- Published
- 1993
- Full Text
- View/download PDF
34. Condrorradionecrosis laríngea
- Author
-
Sancho, E., Escorial, O., Cortés, J.M., Rivas, P., Millán, J., and Vallés, H.
- Published
- 2003
- Full Text
- View/download PDF
35. Metacognitive Beliefs and Emotional Dysregulation Have a Specific Contribution on Worry and the Emotional Symptoms of Generalized Anxiety Disorder
- Author
-
Salguero, José M., primary, Ramos-Cejudo, J., additional, and García-Sancho, E., additional
- Published
- 2019
- Full Text
- View/download PDF
36. Subalpine forest dynamics reconstructed throughout the last 700 years in the Central Pyrenees by means of tree rings and pollen
- Author
-
Institut d'Estudis Catalans, Organismo Autónomo Parques Nacionales (España), Cañellas-Boltà, Núria [0000-0003-2566-4885], Garcés, Sandra, Gutiérrez, Emilia, Martínez-Sancho, E., Dorado Liñán, I., Camarero, Jesús Julio, Cañellas-Boltà, Núria, Vegas-Vilarrúbia, Teresa, Institut d'Estudis Catalans, Organismo Autónomo Parques Nacionales (España), Cañellas-Boltà, Núria [0000-0003-2566-4885], Garcés, Sandra, Gutiérrez, Emilia, Martínez-Sancho, E., Dorado Liñán, I., Camarero, Jesús Julio, Cañellas-Boltà, Núria, and Vegas-Vilarrúbia, Teresa
- Abstract
Understanding how climate has modulated forest growth and composition in the past is necessary to predict the influence of the ongoing climate warming on the dynamics of mountain forests. We studied the past dynamics of subalpine Pyrenean forests during the last 700 years by assessing the relationships between sedimentary pollen and tree-ring records, and their link with climatic drivers. We compared the pollen record and the montane pollen ratio, an integrative index obtained from sedimentary pollen that allows inferring past altitudinal variations in the montane–subalpine ecotone, with tree-ring width from mountain pine (Pinus uncinata) subalpine forests located in Central Pyrenees. To assess climate–growth associations, we related the dendrochronological data with instrumental meteorological records (1901–2010) and temperature reconstructions from the Pyrenees and Northern Hemisphere. Few robust associations were found between arboreal pollen taxa and tree-ring width series of the surrounding forests. However, significant correlations were found between the montane pollen ratio and tree-ring width series from nearby forests (located less than 10 km apart). This relationship could be potentially useful to infer long-term forest growth changes at decadal to centennial scales using the montane pollen ratio. On the contrary, our results show that tree radial growth has mainly been constrained by low temperatures although the growth sensitivity to climate has considerably varied over the last 700 years. Similar results were obtained for the last century as growth variability of these high-elevation forests is still driven by low temperatures, but a relaxation of this constrain in recent decades has been detected. © The Author(s) 2018.
- Published
- 2018
37. Characteristics and management of primary and other immune thrombocytopenias: Spanish registry study
- Author
-
PALAU, JUAN, Sancho E, Herrera M, Sánchez S, Mingot ME, Upegui RI, Rodríguez Salazar MJ, de la Cruz F, Fernández MC, González López TJ, Hernández JJ, Ríos E, López-Fernández MF, García M, Hernández JÁ, and Sanz MA
- Subjects
response ,hemic and lymphatic diseases ,platelet count ,intravenous immunoglobulins ,Immune thrombocytopenia ,corticosteroids - Abstract
Background: The natural history and its modulation by treatments administered for immune thrombocytopenia (ITP) in the clinical practice remains unknown. In addition, little information is available on the characteristics and management of ITP in Spain. Methods: We conducted an observational, multicenter, registry in 70 Hematology Services from Spain between 2009 and 2011, which included children from 2 months of age and adults with primary ITP or another ITP diagnosed within the last 6 months (platelet count [PC] < 100 x 10(9)/l). Patients were followed-up at 6 and 12 months. Results: 484 patients were included (median [Q1, Q3] age 52 [29,74] years, 87.6% adults), 56% women, 10.5% with secondary ITP. Median (Q1, Q3) PC at diagnosis was 12 x 10(9)/l (4, 32); 72% of patients had bleeding symptoms (62% cutaneous bleeding, 29% oral cavity bleeding, 18% epistaxis). 81% of patients with primary ITP received first-line treatment, mainly with corticosteroids (>6 weeks in 59% of cases), either alone (41%) or associated with intravenous immunoglobulin (33%). The response (>= 30 x 10(9)/L) to first-line treatment was 92%. A total of 19% of patients received second-line treatment and 6% additional treatments. At 12 months, 74% of primary ITP patients maintained a PC >= 100 x 10(9)/L in absence of treatment (10% still had hemorrhagic manifestations). Conclusions: Characteristics of Spanish ITP patients are comparable to those from other countries. Although a high response rate to first-line treatments is observed, at 1 year, the disease persists in around one quarter of patients. Overall therapeutic management in Spain conforms to current recommendations, except for an excessive duration of corticosteroids therapy.
- Published
- 2017
38. Dielectric characterisation and numerical investigation of SrBi2Nb2O9–Bi2O3 composites for applications in microwave range.
- Author
-
Abreu, R. F., Saturno, S. O., do Nascimento, J. P. C., Sancho, E. O., de Morais, J. E. V., Sales, J. C., Gouveia, D. X., de Andrade, H. D., Queiroz Júnior, I. S., and Sombra, A. S. B.
- Subjects
DIELECTRIC resonator antennas ,DIELECTRIC properties ,DIELECTRICS ,MICROWAVES ,BISMUTH ,LEAD titanate ,THERMAL stability - Abstract
We present a study of the dielectric properties and behaviour of dielectric resonator antennas (DRAs) based on SrBi
2 Nb2 O9 (SBN)-Bi2 O3 composites. X-ray diffraction is used for structural characterisation of the samples and it indicates the formation of a new phase after the addition of Bi2 O3 . The temperature coefficient of resonant frequency (τf ) is measured and the results demonstrate that the increment of Bi2 O3 improves the thermal stability of the composites from −345.62 to −235.02 ppm/°C. For the dielectric properties, it is observed that Bi2 O3 additions cause the formation of new phases, which present higher dielectric ϵ' than SBN. Our numerical simulations show that the materials operate as DRAs and that SBN-Bi2 O3 composites could be potential candidates for DRAs operating in the S band. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
39. Functional xylem anatomy of aspen exhibits greater change due to insect defoliation than to drought
- Author
-
Hillabrand, R M, primary, Lieffers, V J, additional, Hogg, E H, additional, Martínez-Sancho, E, additional, Menzel, A, additional, and Hacke, U G, additional
- Published
- 2018
- Full Text
- View/download PDF
40. Assessment of the toxicity of a pesticide with a two-generation reproduction test using Daphnia magna
- Author
-
Sánchez, M, Ferrando, M.D, Sancho, E, and Andreu, E
- Published
- 1999
- Full Text
- View/download PDF
41. Systematic review and meta-analysis deciphering the impact of fibrates on paraoxonase-1 status
- Author
-
Sahebkar A, Hernández-Aguilera A, Abelló D, Sancho E, Camps J, Joven J., Unitat de Recerca Biomèdica, Medicina i Cirurgia, and Universitat Rovira i Virgili
- Subjects
Hypertriglyceridemia ,Ciències de la salut ,HDL ,Health sciences ,Cardiovascular risk ,Colesterol ,Ciencias de la salud ,0026-0495 ,Hipertriacilgliceridèmia ,Sistema cardiovascular - Abstract
Objective A significant residual cardiovascular risk is consistently observed in patients treated with statins. A combined treatment with fibrates reduces cardiovascular events in very high-risk patients. Because this is apparently unconnected to an improvement in lipid-related outcomes we hypothesized that the cardioprotective effects of fibrates might be associated with an improvement in paraoxonase-1 (PON1) status. Method The search for existing evidence, using the Medline, Scopus and Cochrane databases, was systematic and followed the PRISMA statement without restrictions on publication date. We excluded non-clinical and observational studies and we extracted data on baseline and post-treatment values of serum PON1 activity and other measurements of PON1 status. Results Nine studies (including 12 treatment arms) in patients with hyperlipidemia, diabetes or metabolic syndrome treated with fibrates, alone or in combination with statins, were included to synthesize results. A meta-analysis of the data using a random-effects model revealed a significant increase in serum PON1 activity following fibrate therapy (WMD: 15.64 U/L, 95% CI: 6.94, 24.34, p < 0.001), an effect that was robust and not sensitive to any particular study. Subgroup analysis indicated differences in the effect size among types of fibrates and that PON1 alterations were associated with high-density lipoprotein cholesterol changes following fibrate therapy. Conclusions Results indicate a significant PON1-enhancing effect of fibrates. Whether this effect is associated with a clinical benefit, although likely, remains to be further investigated.
- Published
- 2016
- Full Text
- View/download PDF
42. Tratamiento con presión positiva continua en los trastornos respiratorios del sueño en los niños
- Author
-
Estivill Sancho E and Miró Nr
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Behavioral therapy ,nervous system diseases ,respiratory tract diseases ,Otorhinolaryngology ,Medicine ,Sleep (system call) ,Continuous positive airway pressure ,Respiratory system ,business ,Intensive care medicine ,therapeutics - Abstract
Continuous positive airway pressure (CPAP) is the first choice in the treatment of apnea-hypopnea syndrome in adults and, in recent years, is considered the second option after surgery in children. CPAP is the best option in children if apnea-hypopnea syndrome persists after surgery. For many professionals in the field, the use of CPAP in all ages of children and adolescents is safe, effective and well tolerated. Follow-up visits are required every 6-12 months, since the mask pressure and size requirements will change depending on children's growth and development. The success of the use of CPAP is closely related to children's tolerance of the CPAP mask. Many professionals have described strategies to improve this tolerance. One of these strategies is to use behavioral therapy, which has been shown be effective in increasing tolerance and performance of the CPAP.
- Published
- 2010
43. SUBCUTANEOUS RITUXIMAB IN B-CELL NON-HODGKIN LYMPHOMA: A SINGLE-CENTER EXPERIENCE
- Author
-
Sanchez-Gonzalez, B., primary, Torres, E., additional, Ferraro, M.P., additional, Garcia-Pallarols, F., additional, Calafell, M., additional, Gale, C., additional, Martinez, L., additional, Sancho, E., additional, Garcia, P., additional, Gimeno, E., additional, and Salar, A., additional
- Published
- 2017
- Full Text
- View/download PDF
44. Analog isolated electronic dynamometer based on a magnetoresistive current sensor
- Author
-
Arcos Carrasco, C., primary, Ramírez Muñoz, D., additional, Ravelo Arias, S. I., additional, Sánchez Moreno, J., additional, Maset Sancho, E., additional, and Garrigós Sirvent, A., additional
- Published
- 2017
- Full Text
- View/download PDF
45. Functional xylem anatomy of aspen exhibits greater change due to insect defoliation than to drought.
- Author
-
Hillabrand, R M, Lieffers, V J, Hogg, E H, Martínez-Sancho, E, Menzel, A, and Hacke, U G
- Subjects
TREE-rings ,XYLEM ,POPULUS tremuloides ,DEFOLIATION ,CAVITATION ,DROUGHTS - Abstract
The study of tree rings can reveal long-term records of a tree's response to the environment. This dendroecological approach, when supplemented with finer-scale observations of the xylem anatomy, can provide novel information about a tree's year-to-year anatomical and hydraulic adjustments. Here we use this method in aspen (Populus tremuloides Michx.) to identify xylem response to drought and insect defoliation. Surprisingly, we found that precipitation influenced vessel diameter mostly in the trees' youth, while this correlation was less pronounced at maturity. This is likely due to a reduction in stress the stand experiences as it ages, and reflects an ability to mediate drought stress as trees mature. Defoliation events caused consistent and profound changes in fiber anatomy likely leading to reduced structural support to vessels. We therefore expect that in years of defoliation trees may be vulnerable to drought-induced cavitation when leaf area recovers. This study highlights how the inclusion of cellular level measurements in tree ring studies provides additional information on how stress events may alter tree functioning through alterations in structure. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
46. Guía práctica de diagnóstico y manejo en la enfermedad de Charcot-Marie-Tooth en España
- Author
-
Sivera Mascaró, R., García Sobrino, T., Horga Hernández, A., Pelayo Negro, A.L., Alonso Jiménez, A., Antelo Pose, A., Calabria Gallego, M.D., Casasnovas, C., Cemillán Fernández, C.A., Esteban Pérez, J., Fenollar Cortés, M., Frasquet Carrera, M., Gallano Petit, M.P., Giménez Muñoz, A., Gutiérrez Gutiérrez, G., Gutiérrez Martínez, A., Juntas Morales, R., Ciano-Petersen, N.L., Martínez Ulloa, P.L., Mederer Hengstl, S., Millet Sancho, E., Navacerrada Barrero, F.J., Navarrete Faubel, F.E., Pardo Fernández, J., Pascual Pascual, S.I., Pérez Lucas, J., Pino Mínguez, J., Rabasa Pérez, M., Sánchez González, M., Sotoca, J., Rodríguez Santiago, B., Rojas García, R., Turon-Sans, J., Vicent Carsí, V., and Sevilla Mantecón, T.
- Abstract
La enfermedad de Charcot-Marie-Tooth (CMT) se clasifica según las características neurofisiológicas e histológicas, el patrón de herencia y el defecto genético subyacente. El objetivo de esta guía es establecer recomendaciones prácticas para el diagnóstico, el pronóstico, el seguimiento y el tratamiento de esta enfermedad en España.
- Published
- 2024
- Full Text
- View/download PDF
47. Systematic review and meta-analysis deciphering the impact of fibrates on paraoxonase-1 status
- Author
-
Unitat de Recerca Biomèdica, Medicina i Cirurgia, Universitat Rovira i Virgili, Sahebkar A, Hernández-Aguilera A, Abelló D, Sancho E, Camps J, Joven J., Unitat de Recerca Biomèdica, Medicina i Cirurgia, Universitat Rovira i Virgili, and Sahebkar A, Hernández-Aguilera A, Abelló D, Sancho E, Camps J, Joven J.
- Abstract
Objective A significant residual cardiovascular risk is consistently observed in patients treated with statins. A combined treatment with fibrates reduces cardiovascular events in very high-risk patients. Because this is apparently unconnected to an improvement in lipid-related outcomes we hypothesized that the cardioprotective effects of fibrates might be associated with an improvement in paraoxonase-1 (PON1) status. Method The search for existing evidence, using the Medline, Scopus and Cochrane databases, was systematic and followed the PRISMA statement without restrictions on publication date. We excluded non-clinical and observational studies and we extracted data on baseline and post-treatment values of serum PON1 activity and other measurements of PON1 status. Results Nine studies (including 12 treatment arms) in patients with hyperlipidemia, diabetes or metabolic syndrome treated with fibrates, alone or in combination with statins, were included to synthesize results. A meta-analysis of the data using a random-effects model revealed a significant increase in serum PON1 activity following fibrate therapy (WMD: 15.64 U/L, 95% CI: 6.94, 24.34, p < 0.001), an effect that was robust and not sensitive to any particular study. Subgroup analysis indicated differences in the effect size among types of fibrates and that PON1 alterations were associated with high-density lipoprotein cholesterol changes following fibrate therapy. Conclusions Results indicate a significant PON1-enhancing effect of fibrates. Whether this effect is associated with a clinical benefit, although likely, remains to be further investigated.
- Published
- 2016
48. Condrorradionecrosis laríngea
- Author
-
Millán J, Cortés Jm, Escorial O, Sancho E, Rivas P, and Vallés H
- Subjects
Larynx ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Cutaneous fistula ,medicine.disease ,Tumor recurrence ,Surgery ,Laryngectomy ,Radiation therapy ,Lesion ,medicine.anatomical_structure ,Otorhinolaryngology ,medicine ,Carcinoma ,medicine.symptom ,Complication ,business - Abstract
Laryngeal chondroradionecrosis is a complication following radiotherapy for laryngeal tumours that may appear many years after the treatment. We present the case of a 78 year old man, that come to the Accident and Emergency department with a prelaryngeal mass and hemoptysis. He had been treated 17 years before with radiotherapy for a vocal cond carcinoma. Posteriorly the lesion did a cutaneous fistula with complete laryngeal exposition and torpid evolution. Post-radiotherapy necrosis in the larynx is a serious complication though not a common one. A tumour recurrence needs to be excluded and even in this case a total laryngectomy is mandatory as it will end in total loss of laryngeal function.
- Published
- 2003
49. The expected number of extreme points of a random linear program.
- Author
-
Sancho E. Berenguer and Robert L. Smith 0002
- Published
- 1986
- Full Text
- View/download PDF
50. Exploring the role of paraoxonases in the pathogenesis of coronary artery disease: a systematic review
- Author
-
Joven J., Camps J., Sancho E., Abelló D., Medicina i Cirurgia, and Universitat Rovira i Virgili.
- Abstract
10.3390/ijms151120997 Paraoxonases (PON) are three enzymes (PON1, PON2 and PON3) that play a role in the organism’s antioxidant system; alterations in which are associated with diseases involving oxidative stress. In this review, we summarize the evidence of PON related to the pathogenesis of coronary artery disease (CAD) and atherosclerosis. We searched three electronic databases (PubMed, Scopus and Cochrane Database) with no date limit. All of the articles selected investigated PON enzymatic activity and/or PON gene polymorphisms. The selection focused on PON in relation to atherosclerosis, CAD and myocardial infarction. The exclusion criteria were a sample size
- Published
- 2014
- Full Text
- View/download PDF
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