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1. (1-oxo-2-substituted-5-indanyloxy)acetic acids, a new class of potent renal agents possessing both uricosuric and saluretic activity. A reexamination of the role of sulfhydryl binding in the mode of action of acylphenoxyacetic acidsaluretics.

Author

Cragoe EJ Jr, Schultz EM, Schneeberg JD, Stokker GE, Woltersdorf OW Jr, Fanelli GM Jr, and Watson LS

Subjects
Acetates chemical synthesis, Animals, Chlorides urine, Diuresis drug effects, Diuretics pharmacology, Dogs, Female, Glycolates chemical synthesis, Glycolates pharmacology, Indans pharmacology, Male, Pan troglodytes, Potassium urine, Rats, Sodium urine, Stereoisomerism, Structure-Activity Relationship, Uricosuric Agents pharmacology, Diuretics chemical synthesis, Indans chemical synthesis, Indenes chemical synthesis, Uricosuric Agents chemical synthesis
Published
1975
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