1. Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles
- Author
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Donthamsetty V. Sowmya, Yerraguravagari Lavanyalatha, Shaik Sharafuddin Basha, Venkatapuram Padmavathi, Palampalli Uma Maheswari Devi, and Adivireddy Padmaja
- Subjects
010405 organic chemistry ,Chemistry ,Stereochemistry ,medicine.drug_class ,Organic Chemistry ,010402 general chemistry ,Antimicrobial ,01 natural sciences ,Anti-inflammatory ,0104 chemical sciences ,carbohydrates (lipids) ,chemistry.chemical_compound ,Nitro ,medicine ,Imidazole ,General Pharmacology, Toxicology and Pharmaceutics ,Antibacterial activity ,Thiazole ,Pyrrole ,Oxazole - Abstract
The acetamido pyrrolyl oxazoles/thiazoles/imidazoles were prepared and tested for their antimicrobial and anti-inflammatory activities. The nitro substituted acetamido pyrrolyl thiazole (11f) and pyrrolyl imidazole (12f) exhibited promising antibacterial activity against K. pneumoniae. The compound 12f showed good antifungal activity against P. chrysogenum. The methoxy acetamido pyrrolyl oxazole (10c) displayed potential anti-inflammatory activity.
- Published
- 2017
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