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[C10H10F3N3OS], monoclinic, P21/c (no. 14), a = 18.555(10) Å, b = 6.785(4) Å, c = 10.139(5) Å, β = 105.86°, V = 1227.9(11) Å3, Z = 4, Rgt(F) = 0.0571, wRref(F2) = 0.1785, T = 296(2) K. [ABSTRACT FROM AUTHOR]

2-(N-tert-butoxycarbonylamino) pyridine and 2-(N-tert-butoxycarbonylamino)-3-methylpyridine were synthesized in a one-step method using either 2-aminopyridine or 2-amino-3-methyphyridine with tert-butylcarbonyl anhydride as the starting materials. The products were characterized by single-crystal X-ray diffraction, 1H NMR, 13C NMR, and HRMS. The biological activity of the two compounds against five fungi was determined. 2-(N-tert-butoxycarbonylamino) pyridine has more than 50% inhibitory activity against Pyricularia oryzae, Colletotrichum gloeosporioides, and Alternaria alternate. In addition, the inhibitory activity of 2-(N-tert-butoxycarbonylamino)-3-methylpyridine against Alternaria alternate reached 67.69%. Two 2-BOC aminopyridine derivatives were synthesized and structurally characterized by 1H NMR, 13C NMR, HRMS analysis and X-ray crystal diffraction. The inhibitory activity both compounds was studied. [ABSTRACT FROM AUTHOR]

[C11H12N4], triclinic, P1̄, a = 6.6939(10) Å, b = 8.8034(13) Å, c = 9.1140(13) Å, α = 97.749(2)°, β = 99.285(2)%, γ = 95.917(2)°, V = 520.90(13) Å3, Z = 2, Rgt(F) = 0.0381, wRref(F2) = 0.1030, T = 296(2) K. [ABSTRACT FROM AUTHOR]