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108 results on '"Shimizu, Takehiro"'

8. P16-2 A retrospective analysis of pembrolizumab in patients with high microsatellite instability cholangiocarcinoma

Author

Shimizu, Takehiro, primary, Naganuma, Atsushi, additional, Matsui, Ayako, additional, Murakami, Tatsuma, additional, Kanamaya, Yuuki, additional, Zennyoji, Dan, additional, Suga, Takayoshi, additional, Tojima, Hiroki, additional, Yamazaki, Yuichi, additional, Kakizaki, Satoru, additional, Sato, Ken, additional, and Uraoka, Toshio, additional

Published
2022
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9. Intrascleral Intraocular Lens Fixation Preserving the Lens Capsule in Cases of Cataract with Insufficient Zonular Support

Author

Kato,Mutsuko, Namba,Michie, Shimoyama,Sachika, Inoue,Mayumi, Ouchi,Chihiro, Shimizu,Takehiro, Kato,Mutsuko, Namba,Michie, Shimoyama,Sachika, Inoue,Mayumi, Ouchi,Chihiro, and Shimizu,Takehiro

Abstract

Mutsuko Kato, Michie Namba, Sachika Shimoyama, Mayumi Inoue, Chihiro Ouchi, Takehiro Shimizu Department of Ophthalmology, Japan Red Cross Okayama Hospital, Okayama, JapanCorrespondence: Mutsuko KatoDepartment of Ophthalmology, Japan Red Cross Okayama Hospital, 2-1-1 Aoe, Kita-ward, Okayama, 700-8607, JapanTel +81 86 222 8811Fax +81 86 222 8841Email mutsukato@okayama-med.jrc.or.jpPurpose: To report our modified simple technique for optic capture and the clinical results of intrascleral IOL fixation preserving the lens capsule, without vitrectomy, in cases of cataract with insufficient zonular support to stabilize the intraocular lens (IOL).Patients and Methods: In 37 eyes of 25 patients with phacodonesis and two or more risk factors for progressive zonular insufficiency, we inserted a CTR to support the capsule and zonules during cataract surgery and IOL fixation; an optic was inserted into the lens capsule, and a haptic was fixed in the scleral tunnel without vitrectomy. In all cases, anterior or total vitrectomy was not needed.Results: The postoperative mean (± standard deviation) tilt and decentration of the implanted IOL did not change from 6 to 12 months (6.77 ± 3.15° to 6.33 ± 3.38° and 0.60 ± 0.30 to 0.61 ± 0.35 mm, respectively). We encountered no late IOL dislocation and no retinal complications, including retinal breaks or cystoid macular oedema, postoperatively (follow-up = 21.1 ± 5.2 months).Conclusion: Our modified techniques preclude the need for vitrectomy. If the lens capsule can be preserved using a CTR, our modified technique can be used to stabilize IOL.Keywords: insufficient zonular support, phacodonesis, lens capsule, capsular tension ring, intrascleral IOL fixation

Published
2022

14. Twist Knot: A New Sliding Noose in Adjustable Suture Strabismus Surgery

Author

Shibata, Kiyo, Hamasaki, Ichiro, Shimizu, Takehiro, Kono, Reika, Ohtsuki, Hiroshi, Morizane, Yuki, and Shiraga, Fumio

Subjects
tensile strength, esotropia, strabismus surgery, adjustable suture, the new sliding noose method
Abstract

To permit noose movement without fraying the sutures following strabismus surgery, we designed a new sliding noose, the “twist knot” and investigated its advantages and disadvantages. We measured the tensile strength required to move the twist knot in a tightly tied state (134±19 gf) and in a loosened state (21±7 gf), and that required to move the conventional sliding noose in a tightly tied state (48±14 gf), and used the Kruskal-Wallis test to compare them. A significant difference was observed among the three tensile strengths (p

Published
2019

15. Shape analysis of rectus extraocular muscles with age and axial length using anterior segment optical coherence tomography

Author

Shibata, Kiyo, Fujiwara, Atsushi, Hamasaki, Ichiro, Shimizu, Takehiro, Kono, Reika, Kanenaga, Keisuke, Nakazawa, Masanori, Morizane, Yuki, Shibata, Kiyo, Fujiwara, Atsushi, Hamasaki, Ichiro, Shimizu, Takehiro, Kono, Reika, Kanenaga, Keisuke, Nakazawa, Masanori, and Morizane, Yuki

Abstract

Purpose This study aimed to evaluate the shape of the extraocular muscles (EOMs) in normal subjects using the en-face images of anterior segment optical coherence tomography (AS-OCT). The EOM insertion and the direction of the muscle fibers were investigated. Subjects and methods A total of 97 healthy normal subjects (194 eyes) at Okayama University Hospital (age, 47.1±21.5 years; range, 8–79 years) participated in the study. A series of 256 tomographic images of the rectus EOMs were captured using the C-scan function of the AS-OCT (CASIA2, TOMEY Co., Japan), and the images were converted to en-face images in multi-TIFF format. The anterior chamber angle to EOM insertion distance (AID) and the angle of the muscle fibers from the insertion site (angle of muscles) were measured from the images. The correlations of AID and angle of muscles with age and axial length were investigated and evaluated. Results AID and angle of muscles were significantly correlated with age or axial length in some EOMs. The AIDs of medial rectus (MR) (P = 0.000) and superior rectus (SR) (P = 0.005) shortened with age. The AIDs of MR (P = 0.001) and inferior rectus (IR) (P = 0.035) elongated with axial length, whereas lateral rectus (LR) (P = 0.013) shortened. The angles of MR (P = 0.001) and LR (P = 0.000) were found to have a more downward direction toward the posterior in older subjects. Conclusion En-face images can be created by AS-OCT, and the shape of the EOMs in normal subjects using these image measurements was available. With the ability to assess the EOMs, AID and angle of muscles are expected give useful information for treating and diagnosing strabismus-related diseases.

Published
2020

19. Critical current density of both F and Cl doped filamentary Hg1223 superconductors

Author

Goto, Tomoko, Shimizu, Takehiro, and Watanabe, Kazuo

Subjects
High temperature superconductivity -- Research, High temperature superconductors -- Research, Business, Electronics, Electronics and electrical industries
Abstract

Filamentary Hg1223 superconductors were doped with F and Cl to improve the transport critical current density (Jc). A solution spinning method was used in preparing the filamentary precursor Ba2Ca2Cu3Re0.2Ox and partially melted in a quartz tube with Hg0.8Ba1.8Ca2Cu3Re0.2(BaF2)0.2(CuCl)0.03Ox. Results indicate that doping improved the reproducibility and stability of high Jc at 77 degrees K and O T. Post-annealing in flowing Ar improved the field dependence of Jc and maintained at 10 to the third power at 77 K at a field of 10 T.

Published
1999

20. Lights-out Surgery for Strabismus Using a Heads-Up 3D Vision System

Author

Hamasaki, Ichiro, Shibata, Kiyo, Shimizu, Takehiro, Kono, Reika, Morizane, Yuki, and Shiraga, Fumio

Subjects
Strabismus, 3D vision system, head-up surgery, Humans, strabismus surgery, Ophthalmologic Surgical Procedures, high dynamic range, video enhancement
Abstract

During strabismus surgery using illumination from a light source, patients complain of photophobia. The NGENUITYⓇ (Alcon) system is equipped with a high-dynamic-range (HDR) camera. A 4K display viewed by wearing circularly polarized glasses provides clear three-dimensional images of the operative field. A light source is usually required for surgeries of the anterior segment (including strabismic surgery), but the digital processing function of the NGENUITYⓇ system allows image display in relatively dark regions even without a light source. We devised a novel ‘lights-out’ surgery that does not use a microscope’s light source, and we examined the usefulness of this technique in 2 cases of strabismic surgery. We performed strabismus surgery using the NGENUITYⓇ system in two patients between January and June 2018. The HDR function was used, and the aperture was opened to the maximum while the gain was adjusted. Surgery was conducted without using the microscope’s light source. We report the 2 cases’ results and evaluate the novel method. The surgeries were performed without problem even though the microscope’s light source was not used. The patients’ photophobia was alleviated. Lights-out surgery is a potentially useful modality for strabismus surgery.

Published
2019

23. The development of broncho-biliary fistula after treatment for hepatocellular carcinoma: a report of two cases.

Author

Takakusagi, Satoshi, Hoshino, Takashi, Takagi, Hitoshi, Naganuma, Atsushi, Yokoyama, Yozo, Kizawa, Kazuko, Marubashi, Kyoko, Kosone, Takashi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Harimoto, Norifumi, Shirabe, Ken, Nobusawa, Sumihito, Zennyoji, Dan, Shimizu, Takehiro, Sato, Ken, Kakizaki, Satoru, and Uraoka, Toshio

Abstract

Broncho-biliary fistula (BBF) is a rare but severe disorder defined as abnormal communication between the biliary system and bronchial tree. Cases of BBF have occasionally been reported, but no standard treatment has been established. We report two cases of BBF that developed after the treatment of hepatocellular carcinoma (HCC) and reviewed the relevant literature. Case 1, a man in his early eighties was diagnosed with BBF 4 months after undergoing surgical resection for HCC (diameter, 7 cm; location, segments 4 and 5). Percutaneous drainage and endoscopic nasobiliary drainage (ENBD) improved BBF without recurrence for more than a year. Case 2, a woman in her late sixties was diagnosed with BBF after percutaneous radiofrequency ablation for HCC. Although the BBF was treated with ENBD, bronchial occlusion, and percutaneous transhepatic portal vein embolization, these treatments were unsuccessful and the patient died. Although non-invasive treatments have been developed, refractory BBF still exists. The prediction of BBF and the development of more effective treatments are necessary to improve outcomes. [ABSTRACT FROM AUTHOR]

Published
2021
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24. Survey on 3-D soil structure of Fukui Plain through microtremor H/V spectrum method

Author

Yasui, Yuzuru, Kojima, Keisuke, Noguchi, Tatsuya, Kagawa, Takao, Mokudai, Satoru, Shimizu, Takehiro, Maeda, Kiyohiro, and Horikawa, Shin-ichi

Subjects
Rayleigh wave, seismic bedrock, Fukui Earthquake Fault, Fukui Plain, genetic algorithm, H/V spectrum, 3-D soil structure, fundamental mode
Abstract

Three-dimensional soil structure in Fukui Plain was estimated from microtremor observations at 1 km mesh points. Depth of alluvial, diluvial, tertiary layers and seismic bedrock were evaluated from the observed H/V spectrum ratios through the GA method. The main features on the seismic bedrock depth in the target area are as follows. There is a deep domain along the west edge of the plain. The depth becomes quickly shallower to westward and gently shallower to eastward. Another deep linear domain estimated along the east edge has possibility of corresponding to the 1948 Fukui Earthquake Fault. Moreover a steep change of bedrock depth is found at the northern side of Asuwayama Hill.

Published
2012

49. Nitrous oxide decomposition active site on Ni–MgO catalysts characterized by X-ray absorption fine structure spectroscopy

Author

Izumi, Yasuo, Shimizu, Takehiro, Kobayashi, Takaaki, and Aika, Ken-ichi

Abstract

A contracted Ni2+ coordination site distorted in the direction of Ni&z.dotdot;Mg and Ni&z.dotdot;Ni was found to be responsible for catalytic N2O decomposition when Ni2+ is diluted in a MgO matrix (Ni2+/Mg2+ atomic ratio ≈ 1.0) based on a local structure study by nickel K-edge X-ray absorption fine structure spectroscopy.

Published
2000

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