1. Longitudinal study of central sensitization and chronic low back pain in a Japanese cohort during the COVID-19 pandemic
- Author
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Shizumasa Murata, Hiroshi Hashizume, Kanae Mure, Hiroyuki Oka, Shingo Inoue, Seiji Kanno, Yuki Matsuyama, Takeru Ueno, Akimasa Murata, Yusuke Kido, Mayumi Sonekatsu, Takashi Shimoe, Hidenobu Tamai, Ryo Taiji, Takuhei Kozaki, Masatoshi Teraguchi, Yoshio Enyo, Yukihiro Nakagawa, Nobuyuki Miyai, and Hiroshi Yamada
- Subjects
Central sensitization ,Chronic low back pain ,COVID-19 pandemic ,Longitudinal study ,Central sensitization inventory (CSI) ,Risk factor ,Medicine ,Science - Abstract
Abstract This study utilized a longitudinal survey in Japan to investigate whether higher Central Sensitization Inventory (CSI) scores, serving as a proxy for central sensitization-related symptoms, are associated with an increased risk of developing chronic low back pain (CLBP), focusing on the impact of the coronavirus disease (COVID-19) pandemic on these conditions. Healthy volunteers (n = 227; mean age: 68.5 ± 9.5 years) were surveyed at baseline (July 2019) and at follow-up (October 2020). The participants were categorized into four groups based on their CLBP status: None, De novo, Continued, and Improved. CLBP prevalence increased from 26% at baseline to 32% at follow-up. Higher baseline CSI scores (odds ratio [OR] 1.05, 95% confidence interval [CI] 1.02–1.09; p = 0.005) and older age (OR 1.06, 95% CI 1.02–1.11; p = 0.007) were identified as significant risk factors for developing CLBP. The mean CSI scores exhibited a slight non-significant increase from 16.9 ± 11.4 to 17.1 ± 11.7. Participants who adhered more strictly to the COVID-19 guidelines and engaged in reduced physical activity reported a higher CLBP prevalence. Our findings suggest that early identification and management of central sensitization are crucial for improving clinical outcomes, particularly during periods of external stress, such as the COVID-19 pandemic.
- Published
- 2025
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