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1. Early combination therapy of COVID-19 in high-risk patients

Author

Orth, Hans Martin, Flasshove, Charlotte, Berger, Moritz, Hattenhauer, Tessa, Biederbick, Kaja D., Mispelbaum, Rebekka, Klein, Uwe, Stemler, Jannik, Fisahn, Matthis, Doleschall, Anna D., Baermann, Ben-Niklas, Koenigshausen, Eva, Tselikmann, Olga, Killer, Alexander, de Angelis, Clara, Gliga, Smaranda, Stegbauer, Johannes, Spuck, Nikolai, Silling, Gerda, Rockstroh, Jürgen K., Strassburg, Christian P., Brossart, Peter, Panse, Jens P., Jensen, Björn-Erik Ole, Luedde, Tom, Boesecke, Christoph, Heine, Annkristin, Cornely, Oliver A., and Monin, Malte B.

Published
2024
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3. Early combination therapy of COVID-19 in high-risk patients

Author

Orth, Hans Martin, primary, Flasshove, Charlotte, additional, Berger, Moritz, additional, Hattenhauer, Sandra Tessa, additional, Biederbick, Kaja D., additional, Mispelbaum, Rebekka, additional, Klein, Uwe, additional, Stemler, Jannik, additional, Fisahn, Matthis, additional, Doleschall, Anna D., additional, Baermann, Ben-Niklas, additional, Koenigshausen, Eva, additional, Tselikmann, Olga, additional, Killer, Alexander, additional, de Angelis, Clara, additional, Gliga, Smaranda, additional, Stegbauer, Johannes, additional, Spuck, Nikolai, additional, Silling, Gerda, additional, Rockstroh, Jürgen K., additional, Strassburg, Christian P., additional, Brossart, Peter, additional, Panse, Jens P., additional, Jensen, Björn-Erik Ole, additional, Luedde, Tom, additional, Boesecke, Christoph, additional, Heine, Annkristin, additional, Cornely, Oliver A., additional, and Monin, Malte B., additional

Published
2023
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4. Antimicrobial Resistance in Gram-Negative Rods Causing Bacteremia in Hematopoietic Stem Cell Transplant Recipients : Intercontinental Prospective Study of the Infectious Diseases Working Party of the European Bone Marrow Transplantation Group

Author

Averbuch, Diana, Tridello, Gloria, Hoek, Jennifer, Mikulska, Malgorzata, Akan, Hamdi, San Segundo, Lucrecia Yaňez, Pabst, Thomas, Özçelik, Tülay, Klyasova, Galina, Donnini, Irene, Wu, Depei, Gülbas, Zafer, Zuckerman, Tsila, de Sousa, Aida Botelho, Beguin, Yves, Xhaard, Aliénor, Bachy, Emmanuel, Ljungman, Per, de la Camara, Rafael, Rascon, Jelena, Camps, Isabel Ruiz, Vitek, Antonin, Patriarca, Francesca, Cudillo, Laura, Vrhovac, Radovan, Shaw, Peter J., Wolfs, Tom, O’Brien, Tracey, Avni, Batia, Silling, Gerda, Sabty, Firas Al, Graphakos, Stelios, Sankelo, Marja, Sengeloev, Henrik, Pillai, Srinivas, Matthes, Susanne, Melanthiou, Frederiki, Iacobelli, Simona, Styczynski, Jan, Engelhard, Dan, and Cesaro, Simone

Published
2017

5. Automated production of specific T cells for treatment of refractory viral infections after allogeneic stem cell transplantation

Author

Heinz, Amadeus T, primary, Calkoen, Friso G.J., additional, Derbich, Alexander, additional, Miltner, Lea, additional, Seitz, Christian, additional, Doering, Michaela, additional, Braun, Christiane, additional, Atar, Daniel, additional, Schumm, Michael, additional, Heubach, Florian, additional, Arendt, Anne-Marie, additional, Schulz, Ansgar, additional, Schuster, Friedhelm R, additional, Meisel, Roland, additional, Strahm, Brigitte, additional, Finke, Juergen, additional, Heineking, Beatrice, additional, Stetter, Susanne, additional, Silling, Gerda, additional, Stachel, Daniel, additional, Gruhn, Bernd, additional, Debatin, Klaus-Michael, additional, Foell, Juergen, additional, Schulte, Johannes H, additional, Woessmann, Wilhelm, additional, Mauz-Körholz, Christine, additional, Tischer, Johanna, additional, Feuchtinger, Tobias, additional, Handgretinger, Rupert, additional, and Lang, Peter, additional

Published
2023
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6. Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia: the SEPIA Study

Author

Koehler, Philipp, Hamprecht, Axel, Bader, Oliver, Bekeredjian-Ding, Isabelle, Buchheidt, Dieter, Doelken, Gottfried, Elias, Johannes, Haase, Gerhard, Hahn-Ast, Corinna, Karthaus, Meinolf, Kekulé, Alexander, Keller, Peter, Kiehl, Michael, Krause, Stefan W., Krämer, Carolin, Neumann, Silke, Rohde, Holger, La Rosée, Paul, Ruhnke, Markus, Schafhausen, Philippe, Schalk, Enrico, Schulz, Katrin, Schwartz, Stefan, Silling, Gerda, Staib, Peter, Ullmann, Andrew, Vergoulidou, Maria, Weber, Thomas, Cornely, Oliver A., and Vehreschild, Maria J.G.T.

Published
2017
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7. Community acquired respiratory virus infections in cancer patients—Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology

Author

von Lilienfeld-Toal, Marie, Berger, Annemarie, Christopeit, Maximilian, Hentrich, Marcus, Heussel, Claus Peter, Kalkreuth, Jana, Klein, Michael, Kochanek, Matthias, Penack, Olaf, Hauf, Elke, Rieger, Christina, Silling, Gerda, Vehreschild, Maria, Weber, Thomas, Wolf, Hans-Heinrich, Lehners, Nicola, Schalk, Enrico, and Mayer, Karin

Published
2016
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9. Early Combination Therapy of COVID-19 in High-Risk Patients

Author

Orth, Hans-Martin, primary, Flaßhove, Charlotte, additional, Berger, Moritz, additional, Hattenhauer, Sandra Tessa, additional, Mispelbaum, Rebekka, additional, Biederbick, Kaja, additional, Klein, Uwe, additional, Stemler, Jannik, additional, Fisahn, Matthis, additional, Doleschall, Anna Dorottya, additional, Baermann, Ben-Niklas, additional, Königshausen, Eva, additional, Tselikmann, Olga, additional, Killer, Alexander, additional, de Angelis, Clara, additional, Gliga, Smaranda, additional, Stegbauer, Johannes, additional, Spuck, Nikolai, additional, Silling, Gerda, additional, Rockstroh, Jürgen K., additional, Strassburg, Christian Peer, additional, Brossart, Peter, additional, Panse, Jens Peter, additional, Jensen, Bjoern-Erik Ole, additional, Luedde, Tom, additional, Boesecke, Christoph, additional, Heine, Annkristin, additional, Cornely, Oliver A., additional, and Monin, Malte Benedikt Benedikt, additional

Published
2023
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10. Long-Term Efficacy and Safety of Luspatercept for Anemia Treatment in Patients With Lower-Risk Myelodysplastic Syndromes: The Phase II PACE-MDS Study

Author

Platzbecker, Uwe, primary, Götze, Katharina S., additional, Kiewe, Philipp, additional, Germing, Ulrich, additional, Mayer, Karin, additional, Radsak, Markus, additional, Wolff, Thomas, additional, Chromik, Joerg, additional, Sockel, Katja, additional, Oelschlägel, Uta, additional, Haase, Detlef, additional, Illmer, Thomas, additional, Al-Ali, Haifa Kathrin, additional, Silling, Gerda, additional, Reynolds, Joseph G., additional, Zhang, Xiaosha, additional, Attie, Kenneth M., additional, Shetty, Jeevan K., additional, and Giagounidis, Aristoteles, additional

Published
2022
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11. Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016

Author

Ullmann, Andrew J., Schmidt-Hieber, Martin, Bertz, Hartmut, Heinz, Werner J., Kiehl, Michael, Krüger, William, Mousset, Sabine, Neuburger, Stefan, Neumann, Silke, Penack, Olaf, Silling, Gerda, Vehreschild, Jörg Janne, Einsele, Hermann, Maschmeyer, Georg, and on behalf of the Infectious Diseases Working Party of the German Society for Hematology and Medical Oncology (AGIHO/DGHO) and the DAG-KBT (German Working Group for Blood and Marrow Transplantation)

Published
2016
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12. Rituximab after lymphoma-directed conditioning and allogeneic stem-cell transplantation for relapsed and refractory aggressive non-Hodgkin lymphoma (DSHNHL R3): an open-label, randomised, phase 2 trial

Author

Glass, Bertram, Hasenkamp, Justin, Wulf, Gerald, Dreger, Peter, Pfreundschuh, Michael, Gramatzki, Martin, Silling, Gerda, Wilhelm, Christian, Zeis, Matthias, Görlitz, Anke, Pfeiffer, Sebastian, Hilgers, Reinhard, Truemper, Lorenz, and Schmitz, Norbert

Published
2014
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13. High‐dose melphalan‐based sequential conditioning chemotherapy followed by allogeneic haematopoietic stem cell transplantation in adult patients with relapsed or refractory acute myeloid leukaemia

Author

Steckel, Nina K., Groth, Christoph, Mikesch, Jan‐Henrik, Trenschel, Rudolf, Ottinger, Hellmut, Kordelas, Lambros, Mueller‐Tidow, Carsten, Schliemann, Christoph, Reicherts, Christian, Albring, Joern C., Silling, Gerda, Schmidt, Eva, Berdel, Wolfgang E., Lenz, Georg, Ditschkowski, Markus, Beelen, Dietrich W., and Stelljes, Matthias

Published
2018
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15. Microbiota-based markers predictive of development of Clostridioides difficile infection

Author

Berkell, Matilda, Mysara, Mohamed, Xavier, Britto Basil, van Werkhoven, Cornelis H., Monsieurs, Pieter, Lammens, Christine, Ducher, Annie, Vehreschild, Maria J.G.T., Goossens, Herman, de Gunzburg, Jean, Bonten, Marc J. M., Malhotra, Surbhi, Ahmed, Mohamed Mysara, Engbers, Annemarie, de Regt, Marieke, Biehl, Lena M., Cornely, Oliver A., Jazmati, Nathalie, Bouverne, Marie-Noelle, Sablier-Gallis, Frederique, Mentre, France, Merle, Uta, Stallmach, Andreas, Rupp, Jan, Bogner, Johannes, Lubbert, Christoph, Silling, Gerda, Witzke, Oliver, Gikas, Achilleas, Maraki, Sofia, Daikos, George, Tsiodras, Sotirios, Skoutelis, Athanasios, Sambatakou, Helen, Pujol, Miguel, Dominguez-Luzon, M. Angeles, Aguado, Jose M., Bouza, Emilio, Cobo, Javier, Rodriguez-Bano, Jesus, Almirante, Benito, de la Cisneros, Julian Torre, Florescu, Simin A., Nica, Maria, Vata, Andrei, Hristea, Adriana, Lupse, Mihaela, Herghea, Delia, Postil, Deborah, Barraud, Olivier, Molina, Jean-Michel, De Lastours, Victoire, Guimard, Thomas, Talarmin, Jean-Philippe, Duval, Xavier, Bernard, Louis, Launay, Odile, ANTICIPATE Study Group, Engbers, Annemarie, de Regt, Marieke, Biehl, Lena M., Cornely, Oliver A., Jazmati, Nathalie, Bouverne, Marie-Noelle, Sablier-Gallis, Frederique, Mentré, France, Merle, Uta, Stallmach, Andreas, Rupp, Jan, Bogner, Johannes, Lübbert, Christoph, Silling, Gerda, Witzke, Oliver, Gikas, Achilleas, Maraki, Sofia, Daikos, George, Tsiodras, Sotirios, Skoutelis, Athanasios, Sambatakou, Helen, Pujol, Miquel, Dominguez-Luzon, M. Angeles, Aguado, Jose M., Bouza, Emilio, Cobo, Javier, Rodríguez-Baño, Jesús, Almirante, Benito, de la Torre Cisneros, Julian, Florescu, Simin A., Nica, Maria, Vata, Andrei, Hristea, Adriana, Lupse, Mihaela, Herghea, Delia, Postil, Deborah, Barraud, Olivier, Molina, Jean-Michel, De Lastours, Victoire, Guimard, Thomas, Talarmin, Jean-Philippe, Duval, Xavier, Bernard, Louis, and Launay, Odile

Subjects
0301 basic medicine, Male, Malalties bacterianes grampositives, genetic structures, Antibiotics, Medizin, General Physics and Astronomy, Prevotella, Prospective Studies, Prospective cohort study, Bifidobacterium, Multidisciplinary, biology, Microbiota, Middle Aged, 3. Good health, Anti-Bacterial Agents, Diarrhea, Cohort, Female, medicine.symptom, Engineering sciences. Technology, medicine.medical_specialty, medicine.drug_class, Science, 030106 microbiology, Predictive markers, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, Microbiome, Aged, Gram-positive bacterial infections, Bacteria, business.industry, Clostridioides difficile, General Chemistry, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, 030104 developmental biology, Next-generation sequencing, Clostridium Infections, Human medicine, business, Dysbiosis, Biomarkers
Abstract

Antibiotic-induced modulation of the intestinal microbiota can lead to Clostridioides difficile infection (CDI), which is associated with considerable morbidity, mortality, and healthcare-costs globally. Therefore, identification of markers predictive of CDI could substantially contribute to guiding therapy and decreasing the infection burden. Here, we analyze the intestinal microbiota of hospitalized patients at increased CDI risk in a prospective, 90-day cohort-study before and after antibiotic treatment and at diarrhea onset. We show that patients developing CDI already exhibit significantly lower diversity before antibiotic treatment and a distinct microbiota enriched in Enterococcus and depleted of Ruminococcus, Blautia, Prevotella and Bifidobacterium compared to non-CDI patients. We find that antibiotic treatment-induced dysbiosis is class-specific with beta-lactams further increasing enterococcal abundance. Our findings, validated in an independent prospective patient cohort developing CDI, can be exploited to enrich for high-risk patients in prospective clinical trials, and to develop predictive microbiota-based diagnostics for management of patients at risk for CDI., Clostridioides difficile infection (CDI) is the most common cause of antibiotic-associated diarrhoea (AAD); however, markers predictive of CDI or AAD development are as yet lacking. Here, to identify markers predictive of CDI, the authors profile the intestinal microbiota of 945 hospitalised patients from 34 hospitals in 6 different European countries and show distinct microbiota enriched in Enterococcus and depleted of Ruminococcus, Blautia, Prevotella and Bifidobacterium compared to non-CDI patients.

Published
2021
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16. Matched-paired analysis of patients treated for invasive mucormycosis: standard treatment versus posaconazole new formulations (MoveOn)

Author

Salmanton-García, Jon, Seidel, Danila, Koehler, Philipp, Mellinghoff, Sibylle, Herbrecht, Raoul, Klimko, Nikolai, Ráčil, Zdeněk, Falces-Romero, Iker, Ingram, Paul, Benítez-Peñuela, Miguel-Ángel, Rodríguez, José Yesid, Desoubeaux, Guillaume, Barać, Aleksandra, García-Vidal, Carolina, Hoenigl, Martin, Mehta, Sanjay, Cheng, Matthew, Klyasova, Galina, Heinz, Werner, Iqbal, Nousheen, Krause, Robert, Ostermann, Helmut, Penack, Olaf, Schalk, Enrico, Sheppard, Donald, Willinger, Birgit, Wisplinghoff, Hilmar, Vehreschild, J Janne, Cornely, Oliver, Vehreschild, Maria, Khedr, Reham Abdelaziz, Arencibia-Núñez, Alberto, Avilés-Robles, Martha, Banke, Ingo, Basher, Ariful, Benachinamardi, Keertilaxmi, Bertz, Harmut, Chakrabarti, Arunaloke, Drgona, Lubos, García-Martínez, Jesús, García-Rodríguez, Julio, Gräber, Sandra, Härter, Georg, Klein, Michael, Kouba, Michal, Lee, Dong-Gun, Le Govic, Yohann, Leo, Fabian, Maertens, Johan, Maschmeyer, Georg, Meintker, Lisa, Mo, Xiao-Dong, Müller, Lena-Katharina, Müller, Nicolas, Nel, Jeremy Stephen, Novák, Jan, Patel, Atul, Pfäfflin, Frieder, Pozo-Laderas, Juan-Carlos, Puerta-Alcalde, Pedro, Rodríguez-Guardado, Azucena, Schroers, Roland, Shekar, Vandana, Shenoi, Susan, Silling, Gerda, Vinh, Donald, Waizel-Haiat, Salomón, Yee Yee, Mandy Yap, Prakash, Peralam Yegneswaran, Žák, Pavel, Groupe d'Étude des Interactions Hôte-Pathogène (GEIHP), Université d'Angers (UA), Service d'Hématologie, CHU Strasbourg, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Medicine, Medical University Graz, Schwerpunkt Infektiologie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Department of Haematology and Oncology, Medical Clinic III, University Hospital Munich—Großhadern, Ludwig Maximilian University, Klinik für Hämatologie und Onkologie, Charité, Campus Benjamin Franklin, Department of Haematology/Oncology, Magdeburg University Hospital, McGill University = Université McGill [Montréal, Canada], Medizinische Universität Wien = Medical University of Vienna, University Hospital of Cologne [Cologne], Postgraduate Institute of Medical Education and Research, Laboratoire de psychologie cognitive (LPC), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Anofel Cryptosporidium National Network, Department of Hematology, University Hospital Gasthuisberg, Medizinische Klinik, Hämatologie und Onkologie, Klinikum Ernst von Bergmann, Real Expression Artificial Life (IRIT-REVA), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Medizinische Klinik A des Universitätsklinikums Münster, Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), University Hospital Gasthuisberg [Leuven], Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), and Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
Male, 0301 basic medicine, Posaconazole, Antifungal Agents, [SDV]Life Sciences [q-bio], Gastroenterology, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Amphotericin B, Pharmacology (medical), Prospective Studies, Registries, 030212 general & internal medicine, Child, Prospective cohort study, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, ComputingMilieux_MISCELLANEOUS, Antiinfective agent, Standard treatment, Middle Aged, 3. Good health, Infectious Diseases, Tolerability, Child, Preschool, Mucorales, Female, medicine.drug, Adult, Microbiology (medical), medicine.medical_specialty, Adolescent, Drug Compounding, Matched-Pair Analysis, 030106 microbiology, Young Adult, 03 medical and health sciences, Pharmacokinetics, Internal medicine, parasitic diseases, medicine, Humans, Mucormycosis, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, [INFO]Computer Science [cs], Aged, Pharmacology, business.industry, Infant, Newborn, Infant, Triazoles, medicine.disease, business, MESH: amphotericin b, antifungal agents, cancer, kidney failure, mucormycosis, surgical procedures, operative, suspensions, mortality, posaconazole, Invasive Fungal Infections
Abstract

Background First-line antifungal treatment for invasive mucormycosis (IM) consists of liposomal amphotericin B. Salvage treatment options are limited and often based on posaconazole oral suspension. With the approval of posaconazole new formulations, patients could benefit from improved pharmacokinetics, safety and tolerability. Objectives Our aim was to assess the effectiveness of posaconazole new formulations for IM treatment. Methods We performed a case-matched analysis with proven or probable IM patients from the FungiScope® Registry. First-line posaconazole new formulations (1st-POSnew) and first-line amphotericin B plus posaconazole new formulations (1st-AMB+POSnew) cases were matched with first-line amphotericin B-based (1st-AMB) treatment controls. Salvage posaconazole new formulations (SAL-POSnew) cases were matched with salvage posaconazole oral suspension (SAL-POSsusp) controls. Each case was matched with up to three controls (based on severity, haematological/oncological malignancy, surgery and/or renal dysfunction). Results Five patients receiving 1st-POSnew, 18 receiving 1st-AMB+POSnew and 22 receiving SAL-POSnew were identified. By day 42, a favourable response was reported for 80.0% (n = 4/5) of patients receiving 1st-POSnew, for 27.8% (n = 5/18) receiving 1st-AMB+POSnew and for 50.0% (n = 11/22) receiving SAL-POSnew. Day 42 all-cause mortality of patients receiving posaconazole new formulations was lower compared with controls [20.0% (n = 1/5) in 1st-POSnew versus 53.3% (n = 8/15) in 1st-AMB; 33.3% (n = 6/18) in 1st-AMB+POSnew versus 52.0% (n = 26/50) in 1st-AMB; and 0.0% (n = 0/22) in SAL-POSnew versus 4.4% (n = 2/45) in SAL-POSsusp]. Conclusions Posaconazole new formulations were effective in terms of treatment response and associated mortality of IM. While posaconazole new formulations may be an alternative for treatment of IM, the limited sample size of our study calls for a cautious interpretation of these observations.

Published
2019

17. Testing G-CSF responsiveness predicts the individual susceptibility to infection and consecutive treatment in recipients of high-dose chemotherapy

Author

Straka, Christian, Sandherr, Michael, Salwender, Hans, Wandt, Hannes, Metzner, Bernd, Hübel, Kai, Silling, Gerda, Hentrich, Marcus, Franke, Daniel, Schwerdtfeger, Rainer, Freund, Mathias, Sezer, Orhan, Giagounidis, Alexander, Ehninger, Gerhard, Grimminger, Wolfgang, Engert, Andreas, Schlimok, Günter, Scheid, Christof, Hellmann, Peter, Heinisch, Harald, Einsele, Hermann, Hinke, Axel, and Emmerich, Bertold

Published
2011
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20. Treatment of invasive fungal infections in cancer patients—updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Author

Mousset, Sabine, Buchheidt, Dieter, Heinz, Werner, Ruhnke, Markus, Cornely, Oliver A., Egerer, Gerlinde, Krüger, William, Link, Hartmut, Neumann, Silke, Ostermann, Helmut, Panse, Jens, Penack, Olaf, Rieger, Christina, Schmidt-Hieber, Martin, Silling, Gerda, Südhoff, Thomas, Ullmann, Andrew J., Wolf, Hans-Heinrich, Maschmeyer, Georg, and Böhme, Angelika

Published
2014
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21. Selective ABO immunoadsorption in hematopoietic stem cell transplantation with major ABO incompatibility

Author

Crysandt, Martina, primary, Soysal, Hatice, additional, Jennes, Eva, additional, Holtick, Udo, additional, Mrotzek, Matthias, additional, Rehnelt, Susanne, additional, Holderried, Tobias A. W., additional, Wessiepe, Martina, additional, Kunter, Uta, additional, Wilop, Stefan, additional, Silling, Gerda, additional, Gecht, Judith, additional, Beier, Fabian, additional, Brümmendorf, Tim H., additional, and Jost, Edgar, additional

Published
2021
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23. Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics

Author

van Werkhoven, Cornelis H., Ducher, Annie, Berkell, Matilda, Mysara, Mohamed, Lammens, Christine, Torre-Cisneros, Julian, Rodríguez-Baño, Jesús, Herghea, Delia, Cornely, Oliver A., Biehl, Lena M., Bernard, Louis, Dominguez-Luzon, M. Angeles, Maraki, Sofia, Barraud, Olivier, Nica, Maria, Jazmati, Nathalie, Sablier-Gallis, Frederique, de Gunzburg, Jean, Mentré, France, Malhotra-Kumar, Surbhi, Bonten, Marc J. M., Vehreschild, Maria J. G. T., Engbers, Annemarie M. S., de Regt, Marieke J. A., Goossens, Herman, Xavier, Basil Britto, Bouverne, Marie-Noelle, Monsieurs, Pieter, Merle, Uta, Stallmach, Andreas, Rupp, Jan, Bogner, Johannes, Lübbert, Christoph, Silling, Gerda, Witzke, Oliver, Gikas, Achilleas, Daikos, George, Tsiodras, Sotirios, Skoutelis, Athanasios, Sambatakou, Helen, Pujol, Miquel, Aguado, Jose M., Bouza, Emilio, Cobo, Javier, Almirante, Benito, Florescu, Simin A., Vata, Andrei, Hristea, Adriana, Lupse, Mihaela, Postil, Deborah, Molina, Jean-Michel, De Lastours, Victoire, Guimard, Thomas, Talarmin, Jean-Philippe, Duval, Xavier, Launay, Odile, Innovative Medicines Initiative, European Commission, European Federation of Pharmaceutical Industries and Associations, and ANTICIPATE Study Group

Subjects
Male, 0301 basic medicine, Carbapenem, genetic structures, Antibiotics, Medizin, General Physics and Astronomy, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, Multidisciplinary, Incidence, Incidence (epidemiology), Microbiota, Hazard ratio, Middle Aged, Anti-Bacterial Agents, Hospitalization, Drug Therapy, Combination, Female, Engineering sciences. Technology, Fluoroquinolones, Cohort study, medicine.drug, medicine.medical_specialty, medicine.drug_class, Science, 030106 microbiology, Bacterial diseases, Antibiòtics, Penicillins, Predictive markers, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, medicine, Humans, Aged, Malalties bacterianes, Clostridioides difficile, business.industry, Clindamycin, Clostridium difficile, General Chemistry, Cephalosporins, Gastrointestinal Microbiome, Carbapenems, Clostridium Infections, Human medicine, business, Biomarkers, Follow-Up Studies
Abstract

Trial enrichment using gut microbiota derived biomarkers by high-risk individuals can improve the feasibility of randomized controlled trials for prevention of Clostridioides difficile infection (CDI). Here, we report in a prospective observational cohort study the incidence of CDI and assess potential clinical characteristics and biomarkers to predict CDI in 1,007 patients ≥ 50 years receiving newly initiated antibiotic treatment with penicillins plus a beta-lactamase inhibitor, 3rd/4th generation cephalosporins, carbapenems, fluoroquinolones or clindamycin from 34 European hospitals. The estimated 90-day cumulative incidences of a first CDI episode is 1.9% (95% CI 1.1-3.0). Carbapenem treatment (Hazard Ratio (95% CI): 5.3 (1.7-16.6)), toxigenic C. difficile rectal carriage (10.3 (3.2-33.1)), high intestinal abundance of Enterococcus spp. relative to Ruminococcus spp. (5.4 (2.1-18.7)), and low Shannon alpha diversity index as determined by 16 S rRNA gene profiling (9.7 (3.2-29.7)), but not normalized urinary 3-indoxyl sulfate levels, predicts an increased CDI risk., Here, the authors report the incidence of Clostridioides difficile infection (CDI) and assess potential clinical characteristics and biomarkers to predict CDI in 1,007 patients of 50 years and above receiving newly initiated antibiotic treatment.

Published
2021

24. Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography

Author

Stelljes, Matthias, Hermann, Sven, Albring, Jörn, Köhler, Gabriele, Löffler, Markus, Franzius, Christiane, Poremba, Christopher, Schlösser, Verena, Volkmann, Sarah, Opitz, Corinna, Bremer, Christoph, Kucharzik, Torsten, Silling, Gerda, Schober, Otmar, Berdel, Wolfgang E., Schäfers, Michael, and Kienast, Joachim

Published
2008
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25. Treatment of invasive fungal infections in cancer patients—Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Author

Böhme, Angelika, Ruhnke, Markus, Buchheidt, Dieter, Cornely, Oliver A., Einsele, Herrmann, Enzensberger, Ruxandra, Hebart, Holger, Heinz, Werner, Junghanss, Christian, Karthaus, Meinolf, Krüger, William, Krug, Utz, Kubin, Thomas, Penack, Olaf, Reichert, Dietmar, Reuter, Stefan, Silling, Gerda, Südhoff, Thomas, Ullmann, Andrew J., and Maschmeyer, Georg

Published
2009
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26. Prophylaxis of invasive fungal infections in patients with hematological malignancies and solid tumors: Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Author

Cornely, Oliver A., Böhme, Angelika, Buchheidt, Dieter, Glasmacher, Axel, Kahl, Christoph, Karthaus, Meinolf, Kern, Winfried, Krüger, William, Maschmeyer, Georg, Ritter, Jörg, Salwender, Hans J., Sandherr, Michael, Schiel, Xaver, Schüttrumpf, Silke, Sieniawski, Michal, Silling, Gerda, Ullmann, Andrew J., and Wolf, Hans-Heinrich

Published
2003
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28. Risk factors for breakthrough invasive fungal infection during secondary prophylaxis

Author

Cornely, Oliver A., Böhme, Angelika, Reichert, Dietmar, Reuter, Stefan, Maschmeyer, Georg, Maertens, Johan, Buchheidt, Dieter, Paluszewska, Monika, Arenz, Dorothee, Bethe, Ullrich, Effelsberg, Jenny, Lövenich, Harry, Sieniawski, Michal, Haas, Antje, Einsele, Hermann, Eimermacher, Hartmut, Martino, Rodrigo, Silling, Gerda, Hahn, Moritz, Wacker, Sidonie, Ullmann, Andrew J., and Karthaus, Meinolf

Published
2008

29. Leitlinie : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen

Author

Schweizerische Gesellschaft Für Hämatologie, Maschmeyer, Georg, Lilienfeld-Toal, Marie Von, Schweizerische Gesellschaft Für Medizinische Onkologie, Silling, Gerda, Sandherr, Michael, Wolf, Hans-Heinrich, Liss, Blasius Janusch, Buchheidt, Dieter, Egerer, Gerlinde, Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Cornely, Oliver Andreas, Rieger, Christina Theresa, Hentrich, Marcus, Vehreschild, Maria J. G. T., Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie, Ullmann, Andrew, Lehners, Nicola, Heinz, Werner, Mayer, Karin Tina, and Mellinghoff, Sibylle Christiane

Subjects
Medizin und Gesundheit
Published
2019
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30. Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation A Randomized Clinical Trial

Author

Bastidas, Adriana de la Serna, Javier El Idrissi, Mohamed and Oostvogels, Lidia Quittet, Philippe Lopez-Jimenez, Javier and Vural, Filiz Pohlreich, David Zuckerman, Tsila Issa, Nicolas C. Gaidano, Gianluca Lee, Je-Jung Abhyankar, Sunil and Solano, Carlos Perez de Oteyza, Jaime Satlin, Michael J. and Schwartz, Stefan Campins, Magda Rocci, Alberto Llamas, Carlos Vallejo Lee, Dong-Gun Tan, Sen Mui Johnston, Anna M. and Grigg, Andrew Boeckh, Michael J. Campora, Laura and Lopez-Fauqued, Marta Heineman, Thomas C. Stadtmauer, Edward A. and Sullivan, Keith M. Alonso Alonso, Aranzazu Anagnostopoulos, Achilles Andreadis, Charalambos (Babis) Angelopoulou, Maria and Anttila, Veli-Jukka Aoun, Mickael Barista, Ibrahim Berkahn, Leanne Bloor, Adrian J. C. Broady, Raewyn Brossart, Peter and Buadi, Francis K. Bulabois, Claude-Eric Cantin, Guy and Cellini, Claudia Chandrasekar, Pranatharthi Haran Chauncey, Thomas Cuneo, Antonio Dadwal, Sanjeet Singh Dickinson, Michael Eom, HyeonSeok Esquirol Sanfeliu, Albert Ferra Coll, Christelle Flomenberg, Phyllis R. Pilar Gonzalez-Rodriguez, Ana and Gottlieb, David J. Grisariu, Sigal Guenther, Andreas and Gutman, Jonathan Hahn, Uwe Heinz, Werner J. Heras, Inmaculada Ikeda, Takashi Jarque, Isidro Karthaus, Meinolf and Kerre, Tessa Kiani, Alexander Klein, Andreas K. Kofla, Grzegorz Kryuchkova, Irina V. Kuo, Ching-Yuan Kuruvilla, John Kuvshinov, Aleksey Kwak, Jae-Yong Lee, Jae Hoon and Lepretre, Stephane Lie, Albert Kwok-Wai Lucchesi, Alessandro and Maertens, Johan Marijt, Erik W. A. Martinez Munoz, Carmen and Michieli, Mariagrazia Milliken, Samuel T. Milpied, Noel and Monserrat Coll, Jorge Mossad, Sherif Beniameen Murphy, John and Navarro Matilla, Maria Belen Novak, Jan Olney, Harold J. Ona Navarrete, Raquel Pascual Cascon, Maria Jesus Peniket, Andy and Penka, Ganeva Piatkowska-Jakubas, Beata Polo Zarzuela, Marta and Quiel, Dimas Rowley, Scott D. Sabry, Waleed Salmi, Tommi Mikael Selleslag, Dominik L. D. Shea, Thomas C. Silling, Gerda Sinisalo, Ulla Marjatta Sohn, Sang Kyun Staib, Peter and Szer, Jeff Theunissen, Koen Topcuoglu, Pervin Tyurina, Natalya G. Uvarov, Mikhail Wahid, Fadilah S. Abdul Yanez San Segundo, Lucrecia Yegin, Zeynep Arzu Yeh, Su-Peng Yip, Sze-Fai Yoon, Sung Soo Young, Jo-Anne H. Zachee, Pierre and Zaja, Francesco ZOE-HSCT Study Grp Collaborators

Abstract

IMPORTANCE Herpes zoster, a frequent complication following autologous hematopoietic stem cell transplantation (HSCT), is associated with significant morbidity. A nonlive adjuvanted recombinant zoster vaccine has been developed to prevent posttransplantation zoster. OBJECTIVE To assess the efficacy and adverse event profile of the recombinant zoster vaccine in immunocompromised autologous HSCT recipients. DESIGN, SETTING, AND PARTICIPANTS Phase 3, randomized, observer-blinded study conducted in 167 centers in 28 countries between July 13, 2012, and February 1, 2017, among 1846 patients aged 18 years or older who had undergone recent autologous HSCT. INTERVENTIONS Participants were randomized to receive 2 doses of either recombinant zoster vaccine (n=922) or placebo (n=924) administered into the deltoid muscle; the first dose was given 50 to 70 days after transplantation and the second dose 1 to 2 months thereafter. MAIN OUTCOMES AND MEASURES The primary end point was occurrence of confirmed herpes zoster cases. RESULTS Among 1846 autologous HSCT recipients (mean age, 55 years; 688 [37%] women) who received 1 vaccine or placebo dose, 1735 (94%) received a second dose and 1366 (74%) completed the study. During the 21-month median follow-up, at least 1 herpes zoster episode was confirmed in 49 vaccine and 135 placebo recipients (incidence, 30 and 94 per 1000 person-years, respectively), an incidence rate ratio (IRR) of 0.32 (95% CI, 0.22-0.44; P

Published
2019

32. Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets

Author

Stelljes, Matthias, Strothotte, Robert, Pauels, Hans-Gerd, Poremba, Christopher, Milse, Michaela, Specht, Christiane, Albring, Jörn, Bisping, Guido, Scheffold, Christian, Kammertoens, Thomas, Oelmann, Elisabeth, Silling, Gerda, Berdel, Wolfgang E., and Kienast, Joachim

Published
2004
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33. Treatment of fungal infections in hematology and oncology

Author

Böhme, Angelika, Ruhnke, Markus, Buchheidt, Dieter, Karthaus, Meinolf, Einsele, Hermann, Guth, Stefan, Heussel, Gudrun, Heussel, Claus-Peter, Junghanss, Christian, Kern, Winfried K., Kubin, Thomas, Maschmeyer, Georg, Sezer, Orhan, Silling, Gerda, Südhoff, Thomas, Szelényi, Hubert, and Ullmann, Andrew J.

Published
2003
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35. Leitlinie : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen

Author

Penack, Olaf, Schweizerische Gesellschaft Für Hämatologie, Kalkreuth, Jana, Lilienfeld-Toal, Marie Von, Maschmeyer, Georg, Weber, Thomas, Klein, Michael, Schweizerische Gesellschaft Für Medizinische Onkologie, Silling, Gerda, Kochanek, Matthias, Wolf, Hans-Heinrich, Hauf, Elke, Schalk, Enrico, Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Berger, Annemarie, Heußel, Claus Peter, Rieger, Christina Theresa, Christopeit, Maximilian Erich Joachim, Hentrich, Marcus, Vehreschild, Maria J. G. T., Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie, Lehners, Nicola, Ullmann, Andrew, and Mayer, Karin Tina

Subjects
Medizin und Gesundheit
Published
2018
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36. CNS infections in patients with hematological disorders (including allogeneic stem-cell transplantation) - Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO)

Author

Schmidt-Hieber, Martin, Silling, Gerda, Wolf, H. H., Ruhnke, M., Schwartz, S., Maschmeyer, G., Schalk, E., Heinz, W., Panse, Jens, Penack, O., Christopeit, M., Buchheidt, D., Meyding-Lamadé, U., and Hähnel, S.

Abstract

Annals of oncology 27(7), 1207-1225 (2016). doi:10.1093/annonc/mdw155, Published by Oxford Univ. Press, Oxford

Published
2016
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37. The Epidemiology of Invasive Aspergillosis and Resistance Patterns of Aspergillus spp. in Germany - Interim Analysis of a Multicenter Observational Study

Author

Vehreschild, Maria J.G.T., Hamprecht, Axel, Adam, Thomas, Bader, Oliver, Becker, Caroline, Bekerdijan-Ding, Isabelle, Buchheidt, Dieter, Doelken, Gottfried, Elias, Johannes, Haase, Gerhard, Hahn-Ast, Corinna, Karthaus, Meinolf, Kekulé, Alexander, Krause, Stefan, Neumann, Silke, Keller, Peter, Kiehl, Michael, Rohde, Holger, La Rosée, Paul, Ruhnke, Markus, Schalk, Enrico, Schafhausen, Philippe, Schwartz, Stefan, Silling, Gerda, Schulz, Katrin, Staib, Peter, Ullmann, Andrew, Weber, Thomas, and Cornely, Oliver A.

Subjects
ddc: 610, 610 Medical sciences, Medicine, skin and connective tissue diseases
Abstract

Introduction: Reports on increasing identification of azole-resistant Aspergillus fumigatus in clinical and environmental isolates have raised concerns with respect to the frequency and clinical relevance of resistant Aspergillus spp. in hematological high-risk patient populations. Methods: In an[for full text, please go to the a.m. URL], Frühjahrstagung der Sektion Antimykotische Chemotherapie 2014

Published
2014

38. Treatment of invasive fungal infections in cancer patients : updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Author

Mousset, Sabine, Buchheidt, Dieter, Heinz, Werner, Ruhnke, Markus, Cornely, Oliver Andreas, Egerer, Gerlinde, Krüger, William, Link, Hartmut, Neumann, Silke, Ostermann, Helmut, Panse, Jens, Penack, Olaf, Rieger, Christina, Schmidt-Hieber, Martin, Silling, Gerda, Südhoff, Thomas, Ullmann, Andrew J., Wolf, Hans-Heinrich, Maschmeyer, Georg, and Böhme, Angelika

Subjects
ddc:610
Abstract

The Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO) here presents its updated recommendations for the treatment of documented fungal infections. Invasive fungal infections are a main cause of morbidity and mortality in cancer patients undergoing intensive chemotherapy regimens. In recent years, new antifungal agents have been licensed, and agents already approved have been studied in new indications. The choice of the most appropriate antifungal treatment depends on the fungal species suspected or identified, the patient’s risk factors (e.g., length and depth of neutropenia), and the expected side effects. This guideline reviews the clinical studies that served as a basis for the following recommendations. All recommendations including the levels of evidence are summarized in tables to give the reader rapid access to the information.

Published
2013

39. Targeting Interleukin-2 to the Bone Marrow Stroma for Therapy of Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation

Author

Schliemann, Christoph, primary, Gutbrodt, Katrin L., additional, Kerkhoff, Andrea, additional, Pohlen, Michele, additional, Wiebe, Stefanie, additional, Silling, Gerda, additional, Angenendt, Linus, additional, Kessler, Torsten, additional, Mesters, Rolf M., additional, Giovannoni, Leonardo, additional, Schäfers, Michael, additional, Altvater, Bianca, additional, Rossig, Claudia, additional, Grünewald, Inga, additional, Wardelmann, Eva, additional, Köhler, Gabriele, additional, Neri, Dario, additional, Stelljes, Matthias, additional, and Berdel, Wolfgang E., additional

Published
2015
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40. Control of Multidrug Resistant Pseudomonas Aeruginosa through Hospital Construction Design and Extensive Environmental and Clinical Surveillance in an Allogeneic Transplantat Unit

Author

Kossow, Annelene, primary, Kipp, Frank, additional, Silling, Gerda, additional, Groll, Andreas H, additional, Rössig, Claudia, additional, Jürgens, Heribert, additional, Mellmann, Alexander, additional, Karch, Helge, additional, Berdel, Wolfgang E, additional, and Stelljes, Matthias, additional

Published
2014
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41. Targeting Interleukin-2 to the Bone Marrow Stroma for Therapy of Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation

Author

Schliemann, Christoph, primary, Gutbrodt, Katrin, additional, Kerkhoff, Andrea, additional, Pohlen, Michele, additional, Wiebe, Stefanie, additional, Silling, Gerda, additional, Angenendt, Linus, additional, Kessler, Torsten, additional, Mesters, Rolf M, additional, Giovannoni, Leonardo, additional, Schäfers, Michael, additional, Altvater, Bianca, additional, Rössig, Claudia, additional, Grünewald, Inga, additional, Wardelmann, Eva, additional, Köhler, Gabriele, additional, Neri, Dario, additional, Stelljes, Matthias, additional, and Berdel, Wolfgang E, additional

Published
2014
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42. Comparison Of Different Pretransplant Predictive Scores In Patients With Refractory Acute Myeloid Leukemia After Allogeneic Stem Cell Transplantation Including Highdose Melphalan: Results Of a Double-Center Observational Study

Author

Steckel, Nina Kristin, primary, Ditschkowski, Markus, additional, Groth, Christoph, additional, Silling, Gerda, additional, Krug, U., additional, Trenschel, Rudolf, additional, Ottinger, Hellmut, additional, Berdel, Wolfgang E, additional, Koldehoff, Michael, additional, Elmaagacli, Ahmet H., additional, Beelen, Dietrich, additional, and Stelljes, Matthias, additional

Published
2013
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44. Treatment of invasive fungal infections in cancer patients—updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

Author

Mousset, Sabine, primary, Buchheidt, Dieter, additional, Heinz, Werner, additional, Ruhnke, Markus, additional, Cornely, Oliver A., additional, Egerer, Gerlinde, additional, Krüger, William, additional, Link, Hartmut, additional, Neumann, Silke, additional, Ostermann, Helmut, additional, Panse, Jens, additional, Penack, Olaf, additional, Rieger, Christina, additional, Schmidt-Hieber, Martin, additional, Silling, Gerda, additional, Südhoff, Thomas, additional, Ullmann, Andrew J., additional, Wolf, Hans-Heinrich, additional, Maschmeyer, Georg, additional, and Böhme, Angelika, additional

Published
2013
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45. Acute Myeloid Leukemia: Longterm Outcome Predicted by Age and Genetic Groups

Author

Buchner, Thomas, primary, Berdel, Wolfgang E., additional, Krug, Utz, additional, Haferlach, Claudia, additional, Schnittger, Susanne, additional, Stelljes, Matthias, additional, Silling, Gerda, additional, Staib, Peter, additional, Grueneisen, Andreas, additional, Reichle, Albrecht, additional, Balleisen, Leopold, additional, Eimermacher, Hartmut, additional, Giagounidis, Aristoteles, additional, Rasche, Herbert, additional, Lengfelder, Eva, additional, Sauerland, Cristina, additional, Heinecke, Achim, additional, Woermann, Bernhard Josef, additional, and Hiddemann, Wolfgang, additional

Published
2012
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46. Population Pharmacokinetics of Liposomal Amphotericin B and Caspofungin in Allogeneic Hematopoietic Stem Cell Recipients

Author

Würthwein, Gudrun, primary, Young, Charlotte, additional, Lanvers-Kaminsky, Claudia, additional, Hempel, Georg, additional, Trame, Mirjam N., additional, Schwerdtfeger, Rainer, additional, Ostermann, Helmut, additional, Heinz, Werner J., additional, Cornely, Oliver A., additional, Kolve, Hedwig, additional, Boos, Joachim, additional, Silling, Gerda, additional, and Groll, Andreas H., additional

Published
2012
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49. Randomized Comparison of Safety and Pharmacokinetics of Caspofungin, Liposomal Amphotericin B, and the Combination of Both in Allogeneic Hematopoietic Stem Cell Recipients

Author

Groll, Andreas H., primary, Silling, Gerda, additional, Young, Charlotte, additional, Schwerdtfeger, Rainer, additional, Ostermann, Helmut, additional, Heinz, Werner J., additional, Gerss, Joachim, additional, Kolve, Hedwig, additional, Lanvers-Kaminsky, Claudia, additional, Vieira Pinheiro, João Paulo, additional, Gammelin, Sibylle, additional, Cornely, Oliver A., additional, and Wuerthwein, Gudrun, additional

Published
2010
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50. Immunological Intervention Triggered by Decreasing CD34 + Lineage-Specific Donor Cell Chimerism to Prevent Relapse of Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT).

Author

Rosenow, Felix, primary, Silling, Gerda, additional, Almut, Berkemeier, additional, Mueller-Tidow, Carsten, additional, Koschmieder, Steffen, additional, Bisping, Guido, additional, Krug, Utz, additional, Buechner, Thomas, additional, Berdel, Wolfgang E, additional, Kienast, Joachim, additional, and Stelljes, Matthias, additional

Published
2009
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