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3. Admissions for posttransplant lymphoproliferative disorder: a 9-year longitudinal analysis of the National (Nationwide) Inpatient Sample.

Author

El-amir, Zain, Jamil, Abdur, Solanki, Dhanshree, Mansuri, Uvesh, Mathew, Midhun, Singh, Jagmeet, Aslam, Shehroz, Akram, Hamza, Mandal, Shobha, and Kichloo, Asim

Abstract

Background: Posttransplant lymphoproliferative disorder (PTLD), a term that encompasses a wide array of malignancies that occur after transplant, can be one of the most devastating transplant complications. While there have been major advancements in care, especially after the landmark PTLD-1 trial in 2012, there is a paucity of information on hospitalizations for PTLD and the changes in hospitalizations over time. Methods: This retrospective cohort study used the National Inpatient Sample to identify hospitalizations for PTLD that occurred between 2009 and 2018. We extracted data for hospitalizations with a primary or secondary diagnosis of PTLD and examined a range of variables, including age, gender, race, hospital type, hospital location, and disposition status. We also collected data on hospital region, median household income, insurance status, and bed size. Results: There was a statistically significant increase in the number of hospitalizations from 2009 to 2019 and an increasing rate of hospitalizations over the study period. Hypertension, electrolyte imbalances, renal failure, and anemia were among the most common comorbidities. We found an increased mortality rate, but this was not statistically significant. Conclusion: Our study provides insight into the changes in hospitalizations for PTLD over nearly a decade, showing an increase in hospitalizations and reports of comorbidities. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Disparities in Outcomes of Hospitalizations Due to Multiple Myeloma: A Nationwide Comparison

Author

Khadka, Sushmita, primary, Balaji, Swetha, additional, Kaur, Japjeet, additional, Solanki, Dhanshree, additional, Kasianchyk, Mariia, additional, Chowdhury, Humayra, additional, Patel, Ishani, additional, Qasim, Muhammad, additional, Desai, Maheshkumar, additional, Maiyani, Prakash, additional, Moradiya, Dharmeshkumar V, additional, Lal, Darshan, additional, Patel, Achint A, additional, and Lekkala, Manidhar, additional

Published
2023
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6. Gastrointestinal Manifestations and Outcomes of COVID-19: A Comprehensive Systematic Review and Meta-analysis

Author

Mehta, Deep, primary, Kelkar, Raveena, additional, Patel, Neel, additional, Trivedi, Parth D, additional, Dawoodi, Sameer, additional, Patel, Dhruvan, additional, Solanki, Dhanshree, additional, Hussain, Akbar, additional, Nagaraj, Sanchitha, additional, Khayat, Azadeh, additional, Samala Venkata, Vikramaditya, additional, Mansuri, Uvesh, additional, Patel, Urvish K, additional, Sacks, Henry, additional, and Atreja, Ashish, additional

Published
2023
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7. S231 Rectal and Anal Ulceration: Analysis of Demographic Trends, Comorbidity Measures, and Outcomes from the National Inpatient Sample Database

Author

Haq, Khwaja S., primary, Solanki, Dhanshree, additional, Ugonabo, Onyinye, additional, Memon, Adil, additional, Iqbal, Unzela, additional, Rajwana, Yasir R., additional, Khan, Zarak H., additional, Ogude, Derick, additional, Varghese, Teresa, additional, Solanki, Shantanu, additional, Khan, Muhammad Ali, additional, Chandra Chakinala, Raja, additional, Jafri, Syed-Mohammed, additional, and Gbadehan, Emmanuel, additional

Published
2023
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10. 243: ECMO USE AND LOWER MORTALITY AMONG CRITICALLY ILL PATIENTS: AN OBSERVATIONAL STUDY

Author

Vinyak, Suprada, primary, Shelar, Vrushali, additional, Bhumanapalli, Sai Akhila Reddy, additional, Akplor, Jerry John, additional, Bhatt, Tulsi, additional, Solanki, Dhanshree, additional, Mendez, Ileana, additional, Abdi, Nawal, additional, Valadez-Cuen, Karen, additional, Shah, Viray, additional, Patel, Digantkumar, additional, Rana, Rishabh Kumar, additional, Patel, Urvish, additional, and Tirupathi, Raghavendra, additional

Published
2022
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11. S688 Acute Gastrojejunal Ulcer With Hemorrhage: Nationwide Trends in Hospitalization, Demographic Disparity, Cost of Care, and Outcomes

Author

Solanki, Shantanu, primary, Haq, Khwaja S., additional, Solanki, Dhanshree, additional, Burney, Anam S., additional, Shah, Harshil, additional, Ghimire, Subash, additional, Kichloo, Asim, additional, Khan, Zarak, additional, Wani, Farah, additional, Yuridullah, Ruhin, additional, Dahiya, Dushyant S., additional, Memon, Adil I., additional, Khan, Hafiz M., additional, Haq, Khwaja F., additional, and Jafri, Syed-Mohammed, additional

Published
2022
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12. S103 Choleperitonitis: A Relatively Rare but Potentially Fatal Entity Encountered in the U.S. Hospitals

Author

Solanki, Shantanu, primary, Solanki, Dhanshree, additional, Haq, Khwaja S., additional, Burney, Anam S., additional, Kichloo, Asim, additional, Dahiya, Dushyant S., additional, Wani, Farah, additional, Mansuri, Uvesh, additional, Patel, Achint, additional, Kapuria, Progga P., additional, Qureshi, Ammar, additional, Memon, Adil I., additional, Khan, Muhammad Ali, additional, Haq, Khwaja F., additional, and Jafri, Syed-Mohammed, additional

Published
2022
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13. S1641 Infection Due to Gastric Band Procedure: Descriptive Analysis of Trends in U.S. Hospitalizations

Author

Solanki, Shantanu, primary, Solanki, Dhanshree, additional, Haq, Khwaja S., additional, Burney, Anam S., additional, Kichloo, Asim, additional, Wani, Farah, additional, Mansuri, Uvesh, additional, Sharma, Purnima, additional, Patel, Anjali, additional, Memon, Adil I., additional, Qureshi, Ammar, additional, Khan, Zarak, additional, Khan, Hafiz M., additional, Haq, Khwaja F., additional, and Jafri, Syed-Mohammed, additional

Published
2022
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14. Increasing Trends of Clostridium difficile Infection in Hospitalized Young Patients: A Study of the National Inpatient Sample From 2007 to 2017

Author

Yang, Tsu Jung, primary, Patel, Achint A, additional, Singh, Jassimran, additional, Jahagirdar, Vinay, additional, Solanki, Dhanshree, additional, Nikhare, Bharati, additional, Harwani, Nishi, additional, Goswami, Ruchir, additional, Devani, Hiteshkumar, additional, Maiyani, Prakash, additional, Moradiya, Dharmeshkumar V, additional, Desai, Maheshkumar, additional, and Muddassir, Salman, additional

Published
2022
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16. Temporal Trends, Predictors, and Outcomes of Disseminated Intravascular Coagulation in Hospitalizations With Sepsis

Author

Solanki, Dhanshree, primary, Lal, Darshan, additional, Sunny, Angel, additional, Han, Xianghui, additional, Iyanar, Swathi, additional, Halder, Abhik, additional, Mullangi, Sanjana, additional, Desai, Maheshkumar, additional, Khan, Uzair, additional, Theli, Abhinay, additional, Devani, Hiteshkumar, additional, Kumar, Piyush, additional, Patel, Achint A, additional, and Lekkala, Manidhar, additional

Published
2022
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19. S1355 Sepsis in Hospitalizations With Short Bowel Syndrome: A 10-Year Analysis From the National Inpatient Sample Database

Author

Solanki, Shantanu, primary, Haq, Khwaja F., additional, Solanki, Dhanshree, additional, Kichloo, Asim, additional, Haq, Khwaja Saad, additional, Patel, Anjali, additional, Qureshi, Ammar, additional, Khan, Hafiz M., additional, Khan, Zarak Hassan, additional, Ichkhanian, Yervant, additional, Chishti, Mohammed Asad, additional, Segovia, Maria C., additional, Schiano, Thomas, additional, and Jafri, Syed-Mohammed, additional

Published
2021
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22. S1057 Endoscopic Retrograde Cholangiopancreatography (ERCP) in Patients With Bariatric Surgery: A Propensity-Matched Analysis

Author

Kichloo, Asim, primary, Solanki, Dhanshree, additional, Dahiya, Dushyant S., additional, Wani, Farah, additional, Singh, Jagmeet, additional, Gandhi, Darshan, additional, Patel, Achint, additional, Haq, Khwaja F., additional, Haq, Khwaja Saad, additional, Chishti, Shania, additional, Solanki, Shantanu, additional, and Khan, Hafiz M., additional

Published
2021
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23. S22 Endoscopic Retrograde Cholangiopancreatography in the Elderly: Trends, Demographic Variations, Complications, and Outcomes

Author

Qureshi, Ammar, primary, Solanki, Dhanshree, additional, Haq, Khwaja F., additional, Patel, Amie, additional, Mansuri, Uvesh, additional, Solanki, Shantanu, additional, Haq, Khwaja Saad, additional, Joshi, Ratna, additional, Kichloo, Asim, additional, Singh, Jagmeet, additional, Khan, Zarak Hassan, additional, Chishti, Mohammed Asad, additional, and Jafri, Syed-Mohammed, additional

Published
2021
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26. sj-pdf-1-smo-10.1177_20503121211022996 – Supplemental material for Pulmonary embolism in chronic kidney disease and end-stage renal disease hospitalizations: Trends, outcomes, and predictors of mortality in the United States

Author

Singh, Jagmeet, Khadka, Sushmita, Solanki, Dhanshree, Kichloo, Asim, Shah, Harshil, Vyas, Manasee J, Chugh, Savneek, Patel, Neil, and Solanki, Shantanu

Subjects
FOS: Veterinary sciences, 111199 Nutrition and Dietetics not elsewhere classified, Cardiology, 170199 Psychology not elsewhere classified, 111799 Public Health and Health Services not elsewhere classified, 110604 Sports Medicine, FOS: Health sciences, 110306 Endocrinology, 110308 Geriatrics and Gerontology, 111099 Nursing not elsewhere classified, 111708 Health and Community Services, 160807 Sociological Methodology and Research Methods, 111702 Aged Health Care, 111403 Paediatrics, 110904 Neurology and Neuromuscular Diseases, 110203 Respiratory Diseases, 110315 Otorhinolaryngology, 70706 Veterinary Medicine, FOS: Clinical medicine, fungi, 110319 Psychiatry (incl. Psychotherapy), FOS: Sociology, FOS: Psychology, 110599 Dentistry not elsewhere classified, 110323 Surgery, 110305 Emergency Medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-pdf-1-smo-10.1177_20503121211022996 for Pulmonary embolism in chronic kidney disease and end-stage renal disease hospitalizations: Trends, outcomes, and predictors of mortality in the United States by Jagmeet Singh, Sushmita Khadka, Dhanshree Solanki, Asim Kichloo, Harshil Shah, Manasee J Vyas, Savneek Chugh, Neil Patel and Shantanu Solanki in SAGE Open Medicine

Published
2021
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29. Endoscopic Retrograde Cholangiopancreatography (ERCP) in Patients With Liver Cirrhosis

Author

Solanki, Shantanu, primary, Kichloo, Asim, additional, Dahiya, Dushyant S., additional, Solanki, Dhanshree, additional, Singh, Jagmeet, additional, Wani, Farah, additional, Albosta, Michael, additional, Ghimire, Subash, additional, Haq, Khwaja F., additional, Khan, Hafiz M.A., additional, Jafri, Syed-Mohammed, additional, Siddiqui, Mohammad Arsalan, additional, and Zuchelli, Tobias, additional

Published
2021
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33. Association of non-alcoholic fatty liver disease with gallstone disease in the United States hospitalized patient population

Author

Kichloo, Asim, primary, Solanki, Shantanu, additional, Haq, Khwaja F, additional, Dahiya, Dushyant, additional, Bailey, Beth, additional, Solanki, Dhanshree, additional, Singh, Jagmeet, additional, Albosta, Michael, additional, Wani, Farah, additional, Aljadah, Michael, additional, Shah, Harshil, additional, Khan, Hafiz, additional, and Jafri, Syed-Mohammed, additional

Published
2021
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37. Dieulafoy's Lesion: Decade-Long Trends in Hospitalizations, Demographic Disparity, and Outcomes

Author

Chakinala, Raja Chandra, primary, Solanki, Shantanu, additional, Haq, Khwaja F, additional, Singh, Jagmeet, additional, Shah, Harshil, additional, Solanki, Dhanshree, additional, Kichloo, Asim, additional, Haq, Khwaja S, additional, Burney, Azam H, additional, Waqar, Shanza, additional, Vyas, Manasee, additional, Chugh, Savneek, additional, and Nabors, Christopher, additional

Published
2020
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38. Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample

Author

Solanki, Shantanu, primary, Chakinala, Raja Chandra, additional, Haq, Khwaja Fahad, additional, Singh, Jagmeet, additional, Khan, Muhammad Ali, additional, Solanki, Dhanshree, additional, Vyas, Manasee J, additional, Kichloo, Asim, additional, Mansuri, Uvesh, additional, Shah, Harshil, additional, Patel, Achint, additional, Haq, Khwaja Saad, additional, Iqbal, Umair, additional, Nabors, Christopher, additional, Khan, Hafiz Muzaffar Akbar, additional, and Aronow, Wilbert S, additional

Published
2020
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39. Trends and outcomes of venous thromboembolism in adult hospitalizations with acute myeloid leukemia: analysis of nationwide inpatient sample from 2010 to 2014.

Author

Khadka, Sushmita, Solanki, Dhanshree, Singh, Jagmeet, Kichloo, Asim, Patel, Neil R., Sharma, Purnima, Chugh, Savneek, and Solanki, Shantanu

Subjects
ACUTE myeloid leukemia, THROMBOEMBOLISM, NOSOLOGY, HOSPITAL mortality, HOSPITAL care
Abstract

Background: Venous thromboembolism (VTE) occurs frequently in acute myeloid leukemia (AML) patients. There are no population-based studies from the United States (U.S.) analyzing this association. The study aims to analyze the trends, predictors of mortality, and outcomes of VTE in AML patients. Methods: We analyzed the publicly available Nationwide Inpatient Sample (NIS) for years 2010–2014. Hospitalizations due to AML were identified by previously validated International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codes as the primary diagnosis. VTE was identified by ICD-9-CM codes as secondary diagnosis. Hospitalizations with age less than 18 years of age were excluded. The trends and outcomes were determined using Chi-squared (χ2) test and multivariate regression models. Results: From 2010 to 2014, there were 313,282 hospitalizations with a primary diagnosis of AML and 1,633 hospitalizations (0.1%) had VTE as a concurrent diagnosis. There was a significant increase in the proportion of AML hospitalizations with VTE from 0.47% in 2010 to 0.56% in 2014 (P = 0.014). Multivariable regression analysis showed that the odds of in-hospital mortality were not higher in AML hospitalizations with VTE (odds ratio [OR] 1.11; 95% confidence interval [CI] 0.81–1.52; P = 0.5) than those without VTE. Age group above 84 years carried the highest risk of mortality (OR 3.20; 95% CI 2.77–3.70; P < 0.0001) in AML-VTE patients. Black (OR 1.23; 95% CI 1.13–1.35; P < 0.0001) and uninsured patients (OR 1.50; 95% CI 1.31–1.73; P < 0.0001) were at significantly higher odds of in-hospital mortality amongst the AML-VTE hospitalizations. Conclusion: The proportion of AML hospitalizations with VTE continues to rise in the U.S. After adjusting for confounders, increasing age, Black race, and lack of insurance were found to have higher risk of in-hospital mortality in the AML-VTE cohort. The odds of in-hospital mortality in AML hospitalizations with VTE are not higher than those without VTE. [ABSTRACT FROM AUTHOR]

Published
2021
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40. Impact of Coexisting Pneumonia in the Patients Admitted with Clostridium DifficileInfection: A Retrospective Study From a National Inpatient Database

Author

Kichloo, Asim, El-Amir, Zain, Dahiya, Dushyant Singh, Singh, Jagmeet, Solanki, Dhanshree, Wani, Farah, and Shaka, Hafeez

Abstract

Clostridium difficileis a gram-positive anaerobic spore forming bacillus that can cause infection in a setting of antibiotic use. Pneumonia is a major cause of morbidity and mortality in an inpatient setting and is frequently associated with significant antibiotic administration. This study aims to compare the outcomes of C. difficileinfection (CDI) with and without pneumonia to determine the impact of pneumonia in hospitalized patients with CDI. This population-based retrospective observational propensity matched analysis study uses data from the National Inpatient Sample database for the years 2016 and 2017. The primary outcomes were in-hospital mortality, total hospital charges, and mean length of stay. Secondary outcomes were the rates of sepsis, septic shock, non-ST elevation myocardial infarction (NSTEMI), acute renal failure, deep vein thrombosis, and pulmonary embolism. In-hospital mortality was noted to be higher in patients with pneumonia than those without (6.5% vs 1.2%, adjusted OR (aOR) 3.85; 95% CI 2.90 to 5.11, p<0.001). The following outcomes were more prevalent in patients with pneumonia compared with those without pneumonia: sepsis (9.8% vs 1.8%, aOR 4.69, 95%?CI 3.73 to 5.87, p<0.001), septic shock (4.0% vs 0.5%, aOR 6.32, 95%?CI 4.43 to 9.03, p<0.001), NSTEMI (1.9% vs 0.5%, aOR 2.95, 95%?CI 1.85 to 4.71, p<0.001), and acute renal failure (31.5% vs 23.1%, aOR 1.23, 95%?CI 1.07 to 1.40, p=0.003). In conclusion, patients with pneumonia were associated with significantly higher rates of system-based complications and higher in-hospital mortality rates.

Published
2021
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42. Admissions for posttransplant lymphoproliferative disorder: a 9-year longitudinal analysis of the National (Nationwide) Inpatient Sample.

Author

El-Amir Z, Jamil A, Solanki D, Mansuri U, Mathew M, Singh J, Aslam S, Akram H, Mandal S, and Kichloo A

Abstract

Background: Posttransplant lymphoproliferative disorder (PTLD), a term that encompasses a wide array of malignancies that occur after transplant, can be one of the most devastating transplant complications. While there have been major advancements in care, especially after the landmark PTLD-1 trial in 2012, there is a paucity of information on hospitalizations for PTLD and the changes in hospitalizations over time., Methods: This retrospective cohort study used the National Inpatient Sample to identify hospitalizations for PTLD that occurred between 2009 and 2018. We extracted data for hospitalizations with a primary or secondary diagnosis of PTLD and examined a range of variables, including age, gender, race, hospital type, hospital location, and disposition status. We also collected data on hospital region, median household income, insurance status, and bed size., Results: There was a statistically significant increase in the number of hospitalizations from 2009 to 2019 and an increasing rate of hospitalizations over the study period. Hypertension, electrolyte imbalances, renal failure, and anemia were among the most common comorbidities. We found an increased mortality rate, but this was not statistically significant., Conclusion: Our study provides insight into the changes in hospitalizations for PTLD over nearly a decade, showing an increase in hospitalizations and reports of comorbidities., Competing Interests: The authors report no funding or conflicts of interest., (Copyright © 2024 Baylor University Medical Center.)

Published
2024
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43. E-cigarette Use and Severe Coronavirus Disease 2019 (COVID-19) Outcomes: A Meta-Analysis.

Author

Valadez-Cuen K, Bhatt T, Mendez IE, Solanki D, Abdi N, Shelar V, Akplor JJ, Reddy Bhumanapalli SA, Vinyak S, Patel D, Tirupathi R, Shah V, Patel UK, and Rana RK

Abstract

E-cigarettes have been known to cause varied poor health outcomes prior to coronavirus disease 2019 (COVID-19), but after the impact of COVID-19, evidence came out that was, in some instances, not as expected regarding the severity of COVID-19 among e-cigarette users (vapers). A meta-analysis was performed on the available evidence to comprehensively find the effect of COVID-19 on existing or past e-cigarette users (vapers). The Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines were used to perform this meta-analysis. PubMed was searched for observational studies that described outcomes after COVID-19 positivity from December 1, 2019, to December 2023. Medical Subject Headings (MeSH) keywords were used for searching the relevant studies highlighting the relationship between COVID-19 and e-cigarette users. Calculations for pooled prevalence, 95% confidence interval (95% CI), weights for current e-cigarette users and vapers, and outcomes (events) were made. To analyze the data, Review Manager V.5.4 was used. The I² statistic was used to assess statistical heterogeneity. The I² statistic of >50% was considered significant heterogeneity. The "leave-one-out" method was used for sensitivity analysis. Out of 3231 studies, four studies reported data on vaping and non-vaping status and composite outcomes, resulting in a sample size of 653 COVID-19-positive cases. The pooled prevalence of being COVID-19 positive, having symptoms, or visiting an emergency room was 7.78% (653/8392). COVID-19 patients with current vaping status had decreased odds of poor outcomes compared to non-smokers, with a pooled odds ratio (OR) of 0.09 (95% CI 0.00-2.42; p>0.05) with heterogeneity between studies (I²=99%, p=0.15). Because of difficulties related to data collection and other factors, this meta-analysis was unable to conclusively establish the correlation between e-cigarette usage and severe COVID-19 outcomes such as hospitalization, admission to the intensive care unit, and fatality. Additional research using more detailed data is necessary to fully understand this correlation., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Valadez-Cuen et al.)

Published
2024
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44. Sepsis during short bowel syndrome hospitalizations: Identifying trends, disparities, and clinical outcomes in the United States.

Author

Dahiya DS, Wachala J, Solanki S, Solanki D, Kichloo A, Holcomb S, Mansuri U, Haq KS, Ali H, Gangwani MK, Shah YR, Varghese T, Khan HMA, Horslen SP, Schiano TD, and Jafri SM

Abstract

Background: Short bowel syndrome (SBS) hospitalizations are often complicated with sepsis. There is a significant paucity of data on adult SBS hospitalizations in the United States and across the globe., Aim: To assess trends and outcomes of SBS hospitalizations complicated by sepsis in the United States., Methods: The National Inpatient Sample was utilized to identify all adult SBS hospitalizations between 2005-2014. The study cohort was further divided based on the presence or absence of sepsis. Trends were identified, and hospitalization characteristics and clinical outcomes were compared. Predictors of mortality for SBS hospitalizations complicated with sepsis were assessed., Results: Of 247097 SBS hospitalizations, 21.7% were complicated by sepsis. Septic SBS hospitalizations had a rising trend of hospitalizations from 20.8% in 2005 to 23.5% in 2014 ( P trend < 0.0001). Compared to non-septic SBS hospitalizations, septic SBS hospitalizations had a higher proportion of males (32.8% vs 29.3%, P < 0.0001), patients in the 35-49 (45.9% vs 42.5%, P < 0.0001) and 50-64 (32.1% vs 31.1%, P < 0.0001) age groups, and ethnic minorities, i.e. , Blacks (12.4% vs 11.3%, P < 0.0001) and Hispanics (6.7% vs 5.5%, P < 0.0001). Furthermore, septic SBS hospitalizations had a higher proportion of patients with intestinal transplantation (0.33% vs 0.22%, P < 0.0001), inpatient mortality (8.5% vs 1.4%, P < 0.0001), and mean length of stay (16.1 d vs 7.7 d, P < 0.0001) compared to the non-sepsis cohort. A younger age, female gender, White race, and presence of comorbidities such as anemia and depression were identified to be independent predictors of inpatient mortality for septic SBS hospitalizations., Conclusion: Septic SBS hospitalizations had a rising trend between 2005-2014 and were associated with higher inpatient mortality compared to non-septic SBS hospitalizations., Competing Interests: Conflict-of-interest statement: Authors declare no conflict of interests for this article., (©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)

Published
2024
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