166 results on '"Spyridis, Nikos"'
Search Results
2. Management of children with febrile seizures: a Greek nationwide survey
- Author
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Kopsidas, Ioannis, Dasoula, Foteini Eleni, Kourkouni, Eleni, Krepi, Adamantia, Mystakelis, Harry Α., Spyridis, Nikos, and Vartzelis, George
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- 2023
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- View/download PDF
3. A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study
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Jackson, Heather Ruth, Zandstra, Judith, Menikou, Stephanie, Hamilton, Shea, McArdle, Andrew J, De, Tisham, Agyeman, Philipp K A, Von Both, Ulrich, Carrol, Enitan D, Emonts, Marieke, Eleftheriou, Irini, Van der Flier, Michiel, Fink, Colin, De Groot, Ronald, Moll, Henriette A, Pokorn, Marko, Pollard, Andrew, Schlapbach, Luregn J, Tsolia, Maria, Usuf, Effua, Wright, Victoria, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Coin, Lachlan JM, Cunnington, Aubrey J, Martinon-Torres, Federico, Herberg, Jethro, De Jonge, Marien I, Levin, Michael, Kuijpers, Taco, Kaforou, Myrsini, Abdulla, Amina, Aebi, Christoph, Agbeko, Rachel, Ali, Ladan, Alkema, Wynand, Allen, Karen, Anderson, Suzanne, Ansari, Imran, Arif, Tasnim, Avramoska, Tanja, Baas, Bryan, Bahovec, Natalija, Balode, Anda, Bãrdzdina, Arta, Barendregt, A M, Barral-Arca, Ruth, Bath, David, Bauchinger, Sebastian, Baumard, Lucas, Baumgart, Hinrich, Baxter, Frances, Bell, Kathryn, Bell, Ashley, Bello, Xabier, Bellos, Evangelos, Benesch, Martin, Bennet, Joshua, Berger, Christoph, Bernhard-Stirnemann, Sara, Bibi, Sagida, Bidlingmaier, Christoph, Binder, Alexander, Binder, Vera, Blackmore, Jennifer, Bojang, Kalifa, Borensztajn, Dorine M, Brengel-Pesce, Karen, Broderick, Claire, Buschbeck, Judith, Calvo-Bado, Leonides, Carnota, Sandra, Carter, Michael J, Castro, María Barreiro, Cebey-López, Miriam, Ceesay, Samba, Ceolotto, Astrid, Chan, Adora, Cocklin, Elizabeth, Collings, Kalvin, Crulley, Stephen, Curras-Tuala, María José, D'alessandro, Umberto, D'Souza, Giselle, Danhauser, Katharina, Darboe, Saffiatou, Darnell, Sarah, De Haan, L, De Vries, Gabriella, Deksne, Dãrta, Devine, Kirsty, Dewez, Juan Emmanuel, Dik, W, Dudley, Julia, Eber, Ernst, Fabian, Daniel, Farto, Cristina Balo, Fernández, Sonia Serén, Fidler, Katy, Fitchett, Elizabeth, Galassini, Rachel, Gallisti, Siegfried, García, Mirian Ben, Gardovska, Dace, Geissler, J, Gerrits, G P J M, Giannoni, Eric, Gloerich, Jolein, Gómez-Carballa, Alberto, González, Fernando Álves, Gores, Gunther, Grãvele, Dagne, Griese, Matthias, Grope, Ilze, Gurung, Meeru, Haas, Nikolaus, Habgood-Coote, Dominic, Hagedoorn, Nienke N, Haidl, Harald, Harrison, Rebekah, Hauer, Almuthe, Heidema, J, Heininger, Ulrich, Henriet, Stefanie, Hibberd, Martin, Hoggart, Cllive, Hösele, Susanne, Hourmat, Sara, Hude, Christa, Huijnen, Martijn, Iglesias, Pilar Leboráns, Iglesias, Marisol Vilas, Jennings, Rebecca, Johnson, Joanne, Jongerius, Ilse, Jorgensen, Rikke, Kahlert, Christian, Kandasamy, Rama, Kappler, Matthias, Keldorfer, Markus, Kelly, Dominic F, Khanijau, Aakash, Kim, Nayoung, Kim, Eunjung, King, Sharon, Kolberg, Laura, Kolnik, Mojca, Kloosterhuis, Lieke, Kohlfürst, Daniela S, Kohlmaier, Benno, Krenn, Larissa, Leigh, Simon, Leitner, Manuel, Leurent, Baptiste, Lim, Emma, Lin, Naomi, Liu, Ching-Chuan, Löffler, Sabine, Lurz, Eberhard, Mackerness, Christine, Maconochie, Ian, Mallet, Francois, Marmarinos, Antonis, Martin, Alex, Martin, Mike, Martinón Sánchez, José María, Martinón-Torres, Nazareth, McAlinden, Paul, McDonald, Sam, McDonell, Anne, Meiere, Anija, Meierford, Anne, Miedema, C J, Miners, Alec, Mistry, Ravi, Mommert, Marine, Morris, Sophie, Muench, Georg, Murdoch, David R, Mustafa, Sobia, Natalucci, Giancarlo, Neeleman, C, Newall, Karen, Nichols, Samuel, Niederer-Loher, Anita, Niedrist, Tobias, Nijman, Ruud, Nokalna, Ieve, Nordberg, Gudrun, O'Connor, Daniel, Obihara, C C, Oliver, Zoe, Oosthoek, Wilma, Ora, Miguel Sadiki, Osterman, Veronika, Pachot, Alexandre, Pajkrt, D, Pardo-Seco, Jacobo, Pavãre, Jana, Paz, Ivonne Pena, Paulus, Stéphane, Pérez, Belén Mosquera, Persand, Salina, Pfleger, Andreas, Pfurtscheller, Klaus, Philipsen, Ria, Pickering, Alisa, Pierce, Benjamin, Pilch, Heidemarie, Pischedda, Sara, Pölz, Lena, Posfay-Barbe, Klara M, Powell, Oliver, Prunk, Petra, Pučuka, Zanda, Rajic, Glorija, Rashid, Aqeela, Redondo-Collazo, Lorenzo, Reiter, Karl, Relly, Christa, Rhodes, Mathew, Rial, Jose Gómez, Richmond, Vivien, Riedel, Thomas, Rivero Calle, Irene, Roca, Anna, Rödl, Siegfried, Rodríguez, Lidia Piñeiro, Rodríguez-Tenreiro, Carmen, Romaine, Sam, Rowlands, Emily, Rudzate, Aleksandra, Sagmeister, Manfred, Saidykhan, Momodou, Sallas, Antonio, Sarr, Isatou, Schoen, Carola, Schonenberg, D, Schweintzger, Nina, Secka, Fatou, Selecka, Katrīna, Shah, Priyen, Shen, Ching-Fen, Shrestha, Shrijana, Skrabl-Baumgartner, Andrea, Soon, Joshua, Sperl, Matthias, Sprenkeler, Evelien, Spyridis, Nikos, Srovin, Tina Plankar, Stampfer, Laura, Stevens, Molly, Stocker, Martin, Strenger, Volker, Suárez, Carlos Durán, Svile, Dace, Syggelou, Kelly, Tal, Chantal, Tambouratzi, Maria, Tavliavini, Emma, Thakker, Clare, Thomson, Evelyn, Throson, Stephen, Till, Holger, Tramper-Stranders, G A, Trasorras, Cristina Serén, Trobisch, Andreas, Urbãne, Urzula Nora, Usman, Mariama, Valentine, Lucille, Van Aerde, Koen, Van den Berg, J M, Van den Broek, Bryan, Van der Giessen, Ilona, Van der Kuip, M, Van der Velden, Fabian, Van Furth, A M, Van Gool, Alain J, Van Leur, M, van Mierlo, G, Vázquez, Sara Ray, Vermont, Clementien, Vicente, Luisa García, Vincek, Katarina, Vito, Ortensia, Voice, Marie, Wallia, Diane, Walsh, Ben, Wang, Shih-Min, Wedderburn, Catherine, Willems, Esther, Wilson, Clare, Wood, Amanda, Woodsford, Phil, Wyss, Verena, Xagorari, Marietta, Zachariasse, Joany, Zaman, Syed M A, Zurl, Christoph, Zwerenz, Manuela, Jackson, Heather R, Hamilton, Melissa Shea, Fischer, Roman, Thorne, Adam M, Huang, Honglei, Tanck, Michael W, Jansen, Machiel H, Pollard, Andrew J, Tsolia, Maria N, Wright, Victoria J, Coin, Lachlan J M, Casals-Pascual, Climent, Herberg, Jethro A, de Jonge, Marien I, and Kuijpers, Taco W
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- 2023
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4. Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study
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Shah, Priyen, Voice, Marie, Calvo-Bado, Leonides, Calle, Irene Rivero, Morris, Sophie, Nijman, Ruud, Broderick, Claire, De, Tisham, Eleftheriou, Irini, Galassini, Rachel, Khanijau, Aakash, Kolberg, Laura, Kolnik, Mojca, Rudzate, Aleksandra, Sagmeister, Manfred, Schweintzger, Nina, Secka, Fatou, Thakker, Clare, Van der Velden, Fabian, Vermont, Clementien, Vincek, Katarina, Agyeman, Philipp K.A., Cunnington, Aubrey J., De Groot, Ronald, Emonts, Marieke, Fidler, Katy, Kuijpers, Taco, Mommert-Tripon, Marine, Brengel-Pesce, Karen, Mallet, Francois, Moll, Henriette, Paulus, Stéphane, Pokorn, Marko, Pollard, Andrew, Schlapbach, Luregn J., Shen, Ching-Fen, Tsolia, Maria, Usuf, Effua, Van der Flier, Michiel, Von Both, Ulrich, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Wright, Victoria, Carrol, Enitan D., Kaforou, Myrsini, Martinon-Torres, Federico, Fink, Colin, Levin, Michael, Herberg, Jethro, Baumard, Lucas, Bellos, Evangelos, Coin, Lachlan, D'Souza, Giselle, Habgood-Coote, Dominic, Hamilton, Shea, Hoggart, Cllive, Hourmat, Sara, Jackson, Heather, Lin, Naomi, Menikou, Stephanie, Nichols, Samuel, Paz, Ivonne Pena, Powell, Oliver, Vito, Ortensia, Wilson, Clare, Abdulla, Amina, Ali, Ladan, Darnell, Sarah, Jorgensen, Rikke, Maconochie, Ian, Mustafa, Sobia, Persand, Salina, Walsh, Ben, Stevens, Molly, Kim, Nayoung, Kim, Eunjung, Pierce, Benjamin, Dudley, Julia, Richmond, Vivien, Tavliavini, Emma, Liu, Ching-Chuan, Wang, Shih-Min, González, Fernando Álves, Farto, Cristina Balo, Barral-Arca, Ruth, Castro, María Barreiro, Bello, Xabier, Ben García, Mirian, Carnota, Sandra, Cebey-López, Miriam, Curras-Tuala, María José, Suárez, Carlos Durán, Vicente, Luisa García, Gómez-Carballa, Alberto, Rial, Jose Gómez, Iglesias, Pilar Leboráns, Martinón-Torres, Nazareth, Martinón Sánchez, José María, Pérez, Belén Mosquera, Pardo-Seco, Jacobo, Rodríguez, Lidia Piñeiro, Pischedda, Sara, Vázquez, Sara Ray, Rodríguez-Tenreiro, Carmen, Redondo-Collazo, Lorenzo, Ora, Miguel Sadiki, Sallas, Antonio, Fernández, Sonia Serén, Trasorras, Cristina Serén, Iglesias, Marisol Vilas, Balode, Anda, Bãrdzdina, Arta, Deksne, Dãrta, Gardovska, Dace, Grãvele, Dagne, Grope, Ilze, Meiere, Anija, Nokalna, Ieve, Pavãre, Jana, Pučuka, Zanda, Selecka, Katrīna, Svile, Dace, Urbãne, Urzula Nora, Bojang, Kalifa, Zaman, Syed M.A., Anderson, Suzanne, Roca, Anna, Sarr, Isatou, Saidykhan, Momodou, Darboe, Saffiatou, Ceesay, Samba, D'alessandro, Umberto, Borensztajn, Dorine M., Hagedoorn, Nienke N., Tal, Chantal, Zachariasse, Joany, Dik, W., Aebi, Christoph, Berger, Christoph, Wyss, Verena, Usman, Mariama, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian, Natalucci, Giancarlo, Relly, Christa, Riedel, Thomas, Cocklin, Elizabeth, Jennings, Rebecca, Johnson, Joanne, Leigh, Simon, Newall, Karen, Romaine, Sam, Tambouratzi, Maria, Marmarinos, Antonis, Xagorari, Marietta, Syggelou, Kelly, Spyridis, Nikos, Blackmore, Jennifer, Harrison, Rebekah, Kohlmaier, Benno, Kohlfürst, Daniela S., Zurl, Christoph, Binder, Alexander, Hösele, Susanne, Leitner, Manuel, Pölz, Lena, Rajic, Glorija, Bauchinger, Sebastian, Baumgart, Hinrich, Benesch, Martin, Ceolotto, Astrid, Eber, Ernst, Gallisti, Siegfried, Gores, Gunther, Haidl, Harald, Hauer, Almuthe, Hude, Christa, Keldorfer, Markus, Krenn, Larissa, Pilch, Heidemarie, Pfleger, Andreas, Pfurtscheller, Klaus, Nordberg, Gudrun, Niedrist, Tobias, Rödl, Siegfried, Skrabl-Baumgartner, Andrea, Sperl, Matthias, Stampfer, Laura, Strenger, Volker, Till, Holger, Trobisch, Andreas, Löffler, Sabine, Dewez, Juan Emmanuel, Hibberd, Martin, Bath, David, Miners, Alec, Fitchett, Elizabeth, Wedderburn, Catherine, Meierford, Anne, Leurent, Baptiste, De Jonge, Marien I., van Aerde, Koen, Alkema, Wynand, van den Broek, Bryan, Gloerich, Jolein, Van Gool, Alain J., Henriet, Stefanie, Huijnen, Martijn, Philipsen, Ria, Willems, Esther, Gerrits, G.P.J.M., Van Leur, M., Heidema, J., De Haan, L., Miedema, C.J., Neeleman, C., Obihara, C.C., Tramper-Stranders, G.A., Kandasamy, Rama, Carter, Michael J., O'Connor, Daniel, Bibi, Sagida, Kelly, Dominic F., Gurung, Meeru, Throson, Stephen, Ansari, Imran, Murdoch, David R., Shrestha, Shrijana, Oliver, Zoe, Lim, Emma, Valentine, Lucille, Allen, Karen, Bell, Kathryn, Chan, Adora, Crulley, Stephen, Devine, Kirsty, Fabian, Daniel, King, Sharon, McAlinden, Paul, McDonald, Sam, McDonell, Anne, Pickering, Alisa, Thomson, Evelyn, Wood, Amanda, Wallia, Diane, Woodsford, Phil, Baxter, Frances, Bell, Ashley, Rhodes, Mathew, Agbeko, Rachel, Mackerness, Christine, Baas, Bryan, Kloosterhuis, Lieke, Oosthoek, Wilma, Arif, Tasnim, Bennet, Joshua, Collings, Kalvin, Van der Giessen, Ilona, Martin, Alex, Rashid, Aqeela, Rowlands, Emily, Soon, Joshua, De Vries, Gabriella, van der Velden, Fabian, Martin, Mike, Mistry, Ravi, Zwerenz, Manuela, Buschbeck, Judith, Bidlingmaier, Christoph, Binder, Vera, Danhauser, Katharina, Haas, Nikolaus, Griese, Matthias, Kappler, Matthias, Lurz, Eberhard, Muench, Georg, Reiter, Karl, Schoen, Carola, Pachot, Alexandre, Mommert, Marine, Srovin, Tina Plankar, Bahovec, Natalija, Prunk, Petra, Osterman, Veronika, Avramoska, Tanja, Jongerius, Ilse, van den Berg, J.M., Schonenberg, D., Barendregt, A.M., Pajkrt, D., van der Kuip, M., van Furth, A.M., Sprenkeler, Evelien, Zandstra, Judith, van Mierlo, G., Geissler, J., Rivero-Calle, Irene, Sagmeister, Manfred G., Schweintzger, Nina A., Kuijpers, Taco W., van der Flier, Michiel, and von Both, Ulrich
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- 2023
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5. Potential benefit from the implementation of the Kaiser Permanente neonatal early-onset sepsis calculator on clinical management of neonates with presumed sepsis
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Kopsidas, Ioannis, Molocha, Nafsika-Maria, Kourkouni, Eleni, Coffin, Susan, Gkentzi, Despoina, Chorianopoulou, Evangelia, Dimitriou, Gabriel, Kapetanaki, Anastasia, Karavana, Georgia, Lithoxopoulou, Maria, Polychronaki, Maria, Roilides, Emmanuel, Triantafyllidou, Pinelopi, Triantafyllou, Christos, Tsopela, Grammatiki-Christina, Tsouvala, Emmanouela, Tsolia, Maria N., Zaoutis, Theoklis, and Spyridis, Nikos
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- 2022
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6. Antibiotic use in Greek Pediatric Hematology-Oncology and Bone Marrow Transplantation units
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Mantadakis, Elpis, primary, Kopsidas, Ioannis, additional, Coffin, Susan, additional, Dimitriou, Gabriel, additional, Gkentzi, Despoina, additional, Hatzipantelis, Emmanuel, additional, Kaisari, Aikaterini, additional, Kattamis, Antonis, additional, Kourkouni, Eleni, additional, Papachristidou, Smaragda, additional, Papakonstantinou, Eugenia, additional, Polychronopoulou, Sophia, additional, Roilides, Emmanuel, additional, Spyridis, Nikos, additional, Tsiodras, Sotirios, additional, Tsolia, Maria, additional, Tsopela, Grammatiki-Christina, additional, Zaoutis, Theoklis, additional, and Tragiannidis, Athanasios, additional
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- 2024
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7. Hand Hygiene Compliance Rates in 9 Pediatric Intensive Care Units Across Europe: Results from the Reducing Antimicrobial use and Nosocomial Infections in Kids Network
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Kopsidas, Ioannis, De Luca, Maia, Bielicki, Julia, Blázquez-Gamero, Daniel, von Both, Ulrich, Ciliento, Gaetano, Epalza, Cristina, Goycochea Validivia, Walter Alfredo, Kolberg, Laura, Lutsar, Irja, Machaira, Maria, Neth, Olaf, Oletto, Andrea, Tsolia, Maria N., Viltrop, Anna-Liisa, Zaoutis, Theoklis, and Spyridis, Nikos
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- 2022
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8. Favorable Outcome in Infants Hospitalized With COVID-19: Single Center Experience from Athens, Greece
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Dimopoulou, Dimitra, Liaska, Marianthi, Eleftheriou, Irini, Kourkouni, Eleni, Tsolia, Maria, and Spyridis, Nikos
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- 2022
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9. Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries
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Irwin, Adam, Akula, Akhila, Bamford, Alasdair, Chang, Amanda, da Silva, Andre, Whitelaw, Andrew, Dramowski, Angela, Vasudevan, Anil Kumar, Sharma, Anita, Justicia, Antonio, Chikkappa, Ashok, Slowinska-Jarzabek, Barbara, Rippberger, Bianca, Zhao, Changan, Tersigni, Chiara, Cheng, Chinglan, Harkensee, Christian, Jing, Chuamei, Zhu, Chunmei, Li, Chunyan, Tagliabue, Claudia, Epalza, Cristina, Jacqueline, Daglish, Tian, Daiyin, Jinka, Dasaratha, Gkentzi, Despoina, Dharmapalan, Dhanya, Benadof, Dona, Papadimitriou, Eleni, Iosifidis, Elias, Roilides, Emmanuel, Yarci, Erbu, Majda-Stanisławska, Ewa, Gowin, Ewelina, Chappell, Faye, Torres, Federico Martinon, Collett-White, Francis, Liu, Gang, Lu, Gen, Syrogiannopoulos, George, Pitsava, Georgia, Alvarez-Uria, Gerardo, Renk, Hana, Mahmood, Hana, Saxen, Harri, Finlayson, Heather, Green, Helen, Rabie, Helena, Kandraju, Hemasree, Zhang, Hong, Okokon, Ita, Cross, Jack, Herberg, Jethro, Li, Jianping, Zhang, Jiaosheng, Deng, Jikui, Liu, Jing, Qian, Jing, Yang, Jinhong, Sicińska, Joanna, Hübner, Johannes, Fukuoka, Kahoru, Yao, Kaihu, Cheung, Kaman, Ojeda, Karla, Kaffe, Katerina, Kreitmeyer, Katharina, Doerholt, Katja, Grimwood, Keith, Ledoare, Kirsty, Vazouras, Konstantinos, Shen, Kunling, Tang, Lanfang, Zhang, Lehai, Lin, Li, Ashkenazi-Hoffnung, Liat, Wu, Lijuan, Wang, Lijun, Teston, Lilian, Galli, Luisa, Speirs, Lynne, Tsolia, Maria, Hufnagel, Markus, Knuf, Markus, Duse, Marzia, Ding, Mingjie, Rozic, Mojca, Premru, Mueller, O'Connell, Natasha, Rieber, Nikolaus, Spyridis, Nikos, Tunga, Onkaraiah, Conejo, Pablo Rojo, McMaster, Paddy, Lumbiganon, Pagakrong, Pansa, Paola, D'Argenio, Patrizia, Moriarty, Paul, Nikolic, Petra, Wang, Ping, Paopongsawan, Pongsatorn, Cao, Qing, Deng, Qiulian, Laxminarayan, Ramanan, Kanithi, Ravishankar, Jimenez, Rodolfo, Cao, Sancheng, Singh, Sanjeev, Rees, Sarah, Praveen, Saroey, Kekomaki, Satu, Hackett, Scott, Ashkenazi, Shai, Chang, Si Min, Drysdale, Simon, Koning, Sonia, Subramanian, Sreeram, Murki, Srinivas, Vergnano, Stefania, Gandra, Sumanth, Esposito, Susanna, Anugulruengkitt, Suvaporn, Puthanakit, Thanyawee, Behrends, Uta, Papaevangelous, Vana, Jian, Victoria, Li, Wei, Zhao, Wei, Wang, Wei, Zhang, Wenshuang, Mu, Xiaoping, Dong, Xiaoyie, Jiang, Xiyuan, Chen, Xu, Wang, Yi, Zheng, Yuejie, Horikoshi, Yuho, Aboderin, Aaron, Olayinka, Adebola, Dedeic-Ljubovic, Amela, McCorry, Ann, Enimil, Anthony, Neubert, Antje, solano, antonio, Pignatari, Antonio, Poojary, Aruna, Kambaralieva, Baktygul, McCullagh, Bernadette, Carevi, Biljana, Van Herendael, Bruno, Gormley, Cairine, Carvajal, Camila, Ramírez, Carlos, Fitzgerald, David, Sabuda, Deana, Konopnicki, Deborah, Lacej, Denada, Pierard, Denis, Rios, Edgar, Marshall, Emily, Firre, Eric, van Elzakker, Erika, Shaqiri, Erjona, Darwish Elhajji, Feras, Gawrys, Gerard, Markovic, Goran, Kunsihima, Hiroyuki, Chen, Hui Hiong, Sviestina, Inese, Pristas, Irina, Hoxha, Iris, Korinteli, Irma, Mareković, Ivana, Soltani, Jafar, Labarca, Jaime, AlSalman, Jameela, Horvatic, Jasminka, Frimpong, Juliet Ampomah, Pagava, Karaman, Kei, Kasahara, Okinaka, Keiji, Iregbu, Kenneth, Ghazaryan, Lilit, Raka, Lul, Gessner-Wharton, Mallory, Aldeyab, Mamoon, Cooper, Mandelin, del Castillo, Marcelo, Hojman, Martin, Hudson, Melissa, Alshehri, Mohamed, Ling, Moi Lin, Greer, Nickie, Oduyebo, Oyinlola, Buijtels, Patricia, TEROL BARRERO, PEDRO, Zarb, Peter, Schelstraete, PEtra, Nwajiobi-Princewill, Princewill Ifeanyi Philip, Khanna, Priya, Quiros, Rodolfo, Simovic, Sanja, Thompson, Sarah, Chan, Si Min, Burokiene, Sigita, Rachina, Svetlana, Usonis, Vytautas, Cornistein, Wanda, Holemans, Xavier, Gu, Yoshiaki, Brothers, Adam, Hersh, Adam, Fernandez, Alfred, Tribble, Alison, Hurst, Amanda, Green, Andrea, Hammer, Benjamin, Lee, Betty P, Kuzmic, Brenik, Shapiro, Craig, Boge, Craig, Haslam, David, Berman, David, Naeem, Fouzia, Johnson, George, Schwenk, Hayden, Orr, Hillary, Maples, Holly, Olsen, Jared, Gerber, Jeffrey, Girotto, Jennifer, Zweiner, Jennifer, Goldman, Jennifer, Gillon, Jessica, Tansmore, Jessica, Manaloor, John, Courter, Joshua, Mongkolrattanothai, Kanokporn, Patel, Karisma, Merkel, Kathryn, Namtu, Katie, Flett, Kelly, Lee, Kelly, Nichols, Kristen, Klein, Kristin, Handy, Lori, Castagnini, Luis, Mazade, Marc, Heger, Margaret, Fernandez, Marisol, Chang, Michael, Crawford, Michelle, Nelson, Miranda, Bennett, Nicholas, Jaggi, Preeti, Hamdy, Rana, Banerjee, Ritu, Olivero, Rosemary, Patel, Sameer, Arnold, Sandra, Ogrin, Sara, Jones, Sarah, Parker, Sarah, Kubes, Sarah, Hymes, Saul, Weissman, Scott, Chan, Shannon, Henderson, Sheryl, Metjian, Talene, Hsia, Yingfen, Lee, Brian R, Versporten, Ann, Yang, Yonghong, Bielicki, Julia, Jackson, Charlotte, Newland, Jason, Goossens, Herman, Magrini, Nicola, and Sharland, Mike
- Published
- 2019
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10. A Survey on National Pediatric Antibiotic Stewardship Programs, Networks and Guidelines in 23 European Countries
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Kopsidas, Ioannis, Vergnano, Stefania, Spyridis, Nikos, Zaoutis, Theoklis, and Patel, Sanjay
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- 2020
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11. Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study
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Warris, Adilia, Pana, Zoi-Dorothea, Oletto, Andrea, Lundin, Rebecca, Castagnola, Elio, Lehrnbecher, Thomas, Groll, Andreas H., Roilides, Emmanuel, Andersen, Cecilie T., Arendrup, Maiken C., Arsenijevic, Valentina Arsic, Bianchini, Sonia, von Both, Ulrich, Chmelnik, Martin, Controzzi, Tiziana, Emonts, Marieke, Esposito, Susanna, Ferreras-Antolin, Laura, Henriet, Stefanie, Iosifidis, Elias, Irwin, Adam, Kopsidas, John, Lagrou, Katrien, Lyall, Hermione, Casteleiro, Angela Manzanares, Mesini, Alessio, Olbrich, Peter, Paulus, Stephane, Lausch, Karen Rokkedal, Soler-Palacin, Pere, Spyridis, Nikos, Strenger, Volker, Theodoraki, Martha, and Wolfs, Tom
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- 2020
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12. LONG TERM EFFECTS OF SARS-COV-2 INFECTION ON CHILDREN'S VASCULATURE
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Karaviti, Dareilena, primary, Charakida, Marietta, additional, Dimopoulou, Dimitra, additional, Eleftheriou, Irini, additional, Liaska, Marianthi, additional, Papadaki, Maria, additional, Maritsi, Despoina, additional, Sakou, Irine-Ikbale, additional, Marmarinos, Antonios, additional, Avgeris, Margaritis, additional, Gourgiotis, Dimitrios, additional, Spyridis, Nikos, additional, and Tsolia, Maria, additional
- Published
- 2023
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13. An Infant With Purpuric Rash and Edema
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Argyri, Ioanna, Korona, Anastasia, Mougkou, Katerina, Vougiouka, Olga, Tsolia, Maria, and Spyridis, Nikos
- Published
- 2015
14. Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves
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Eleftheriou, Irini, primary, Maritsi, Despina, additional, Lampidi, Stavroula, additional, Charisi, Konstantina, additional, Vantsi, Petrina, additional, Skourti, Kleopatra, additional, Filippatos, Filippos, additional, Amplianitis, Ioannis, additional, Dimou, Despina, additional, Papadopoulou-Legbelou, Kyriaki, additional, Papadopoulou-Alataki, Efimia, additional, Kampouridou, Parthena, additional, Koletsi, Patra, additional, Fotis, Lampros, additional, Vergadi, Elena, additional, Gkentzi, Despoina, additional, Farmaki, Evangelia, additional, Papaevangelou, Vassiliki, additional, Galanakis, Emmanouil, additional, Grivea, Ioanna N., additional, Syrogiannopoulos, George A., additional, Spoulou, Vana, additional, Spyridis, Nikos, additional, Michos, Athanasios, additional, Roilides, Emmanuel, additional, and Tsolia, Maria N., additional
- Published
- 2022
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15. Immunogenicity 6 months post COVID-19 mRNA vaccination among adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors
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Dimopoulou, Dimitra, primary, Tsolia, Maria N, additional, Spyridis, Nikos, additional, and Maritsi, Despoina N, additional
- Published
- 2022
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16. Potential benefit from the implementation of the Kaiser Permanente neonatal early-onset sepsis calculator on clinical management of neonates with presumed sepsis
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Kopsidas, Ioannis Molocha, Nafsika-Maria Kourkouni, Eleni and Coffin, Susan Gkentzi, Despoina Chorianopoulou, Evangelia and Dimitriou, Gabriel Kapetanaki, Anastasia Karavana, Georgia and Lithoxopoulou, Maria Polychronaki, Maria Roilides, Emmanuel and Triantafyllidou, Pinelopi Triantafyllou, Christos Tsopela, Grammatiki-Christina Tsouvala, Emmanouela Tsolia, Maria N. and Zaoutis, Theoklis Spyridis, Nikos
- Abstract
To assess the potential benefit from the implementation of the Kaiser Permanente early-onset sepsis calculator (EOS-C), in terms of antibiotic use and requested laboratory tests, in a network of neonatal intensive care units (NICUs) in Greece, and to determine the incidence of early-onset sepsis (EOS) in Greek NICUs, a prospective surveillance study was conducted in 7 NICUs between April 2018 and June 2019. Data were collected for all newborns >= 34 weeks’ gestation receiving empiric antibiotic therapy within the first 3 days of life. The number of live births and positive blood or cerebrospinal fluid cultures within the first 3 days of life were used for calculation of EOS incidence. Evaluation of possible impact of implementing the calculator was done by comparing the clinicians’ recorded management to the calculator’s suggested course of action. The unit-specific incidence of culture-proven EOS ranged between 0 and 2.99/1000 live births. The weighted incidence rate for all 7 units was 1.8/1000 live births. Management of EOS guided by the calculator could lead to a reduction of empiric antibiotic initiation up to 100% for the group of “well-appearing” neonates and 86% for “equivocal,” lowering exposure to antibiotics by 4.2 and 3.8 days per neonate, respectively. Laboratory tests for blood cultures drawn could be reduced by up to 100% and 68%, respectively. Sensitivity of the EOS-C in identifying neonates with positive blood cultures was high. Conclusion: Management strategies based on the Kaiser Permanente neonatal sepsis calculator may significantly reduce antibiotic exposure, invasive diagnostic procedures, and hospitalizations in late preterm and term neonates. What is Known: center dot Neonates are frequently exposed to antibiotics for presumed EOS. center dot The Kaiser Permanente sepsis calculator can reduce antibiotic exposure in neonates.. What is New: center dot EOS calculator can be an effective antibiotic stewardship tool in a high prescribing country and can reduce invasive diagnostic procedures and mother-baby separation. center dot Incidence of EOS in Greece is higher compared to other European countries.
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- 2022
17. Short-course Regimens of Liposomal Amphotericin B for the Treatment of Mediterranean Visceral Leishmaniasis in Children: An 11-year Retrospective Study at a Tertiary Care Center
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Krepis, Panagiotis, Argyri, Ioanna, Krepi, Adamantia, Syrmou, Areti, Spyridis, Nikos, and Tsolia, Maria
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- 2017
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18. Immunogenicity 6 months post COVID-19 mRNA vaccination among adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.
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Dimopoulou, Dimitra, Tsolia, Maria N, Spyridis, Nikos, and Maritsi, Despoina N
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KRUSKAL-Wallis Test ,COVID-19 vaccines ,ANTI-inflammatory agents ,VACCINE immunogenicity ,JUVENILE idiopathic arthritis ,BLOOD collection ,MESSENGER RNA ,DESCRIPTIVE statistics ,VIRAL antibodies ,DATA analysis software - Abstract
Objectives Mass vaccination is the most effective strategy for controlling the COVID-19 pandemic. This study aimed to evaluate the 6-month immunogenicity after BNT162b2-COVID-19 vaccination in adolescents with JIA on TNFi treatment. Methods This single-centre study included adolescents with JIA treated with TNFi for at least 18 months. Patients received two doses of COVID-19 vaccine (Pfizer-BioNTech) from 15 April to 15 May 2021. Quantitative measurement of IgG antibodies to SARS-CoV-2-spike-protein-1 was performed at 1, 3 and 6 months post-vaccination. Results Overall, 21 adolescents with JIA in clinical remission at the time of vaccinations were enrolled. None of them discontinued TNFi/MTX treatment at the time of vaccine administration or during the follow-up period. All patients developed a sustained humoral response against SARS-CoV-2 at 1 and 3 months after vaccination (P < 0.05). The antibody levels decreased significantly at 6 months post-vaccination (P < 0.01). The type of JIA did not reveal any differences in the humoral response at 3 (P = 0.894) or 6 months post-vaccination (P = 0.72). No difference was detected upon comparison of the immunogenicity between the different treatment arms (adalimumab vs etanercept) at 3 (P = 0.387) and 6 months (P = 0.526), or TNFi monotherapy vs combined therapy (TNFi plus methotrexate) at 3 (P = 0.623) and 6 months (P = 0.885). Conclusions Although mRNA vaccines develop satisfactory immunogenicity at 1 month and 3 months post-vaccination in adolescents with JIA on TNFi, SARS-CoV-2 antibody titres decrease significantly overtime, remaining at lower levels at 6 months. Further collaborative studies are required to determine long-term immunogenicity, real duration of immune protection and the need for a booster vaccine dose. [ABSTRACT FROM AUTHOR]
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- 2023
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19. Safety and tolerability of the COVID ‐19 messenger RNA vaccine in adolescents with juvenile idiopathic arthritis treated with tumor necrosis factor inhibitors
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Dimopoulou, Dimitra, primary, Spyridis, Nikos, additional, Vartzelis, George, additional, Tsolia, Maria N., additional, and Maritsi, Despoina N., additional
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- 2022
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20. A national study of antibiotic use in Greek pediatric hematology oncology and bone marrow transplant units
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Mantadakis, Elpis, primary, Kopsidas, Ioannis, additional, Coffin, Susan, additional, Dimitriou, Gabriel, additional, Gkentzi, Despoina, additional, Hatzipantelis, Emmanouel, additional, Kaisari, Aikaterini, additional, Kattamis, Antonis, additional, Kourkouni, Eleni, additional, Papachristidou, Smaragda, additional, Papakonstantinou, Evgenia, additional, Polychronopoulou, Sophia, additional, Roilides, Emmanuel, additional, Spyridis, Nikos, additional, Tsiodras, Sotirios, additional, Tsolia, Maria N., additional, Tsopela, Grammatiki-Christina, additional, Zaoutis, Theoklis, additional, and Tragiannidis, Athanasios, additional
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- 2022
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21. Dosing of oral penicillins in children
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Ahmed, Umar, Spyridis, Nikos, Wong, Ian C K, Sharland, Mike, and Long, Paul F
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- 2011
22. Safety and tolerability of the COVID‐19 mRNA‐vaccine in adolescents with juvenile idiopathic arthritis on treatment with TNF‐inhibitors
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Dimopoulou, Dimitra, Spyridis, Nikos, Vartzelis, George, Tsolia, Maria N., and Maritsi, Despoina N.
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Male ,Adolescent ,SARS-CoV-2 ,Adalimumab ,Headache ,COVID-19 ,Myalgia ,Arthralgia ,Arthritis, Juvenile ,Etanercept ,Injection Site Reaction ,Young Adult ,Methotrexate ,Antirheumatic Agents ,Disease Progression ,Humans ,Female ,Tumor Necrosis Factor Inhibitors ,Letter to the Editor ,BNT162 Vaccine ,Fatigue - Abstract
Patients with rheumatic and musculoskeletal diseases (RMDs) on immunosuppressants are considered a vulnerable group in COVID‐19 pandemic and vaccination is the mainstay for the prevention of this infection (1). To date, recommendations and data for COVID‐19 vaccination in adolescent patients with RMDs are lacking (2). International societies and post‐authorization safety reports of the novel mRNA COVID‐19 vaccines are generally reassuring; nonetheless their safely profile in adolescents with RMDs on immune‐modulating treatment is unknown, since these individuals were excluded from the vaccine trials (3‐5).
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- 2021
23. The Worldwide Antibiotic Resistance and Prescribing in European Children (ARPEC) point prevalence survey: developing hospital-quality indicators of antibiotic prescribing for children
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Versporten, Ann, Bielicki, Julia, Drapier, Nico, Sharland, Mike, Goossens, Herman, Calle, Graciela Maria, Garrahan, Juan P., Clark, Julia, Cooper, Celia, Blyth, Christopher C., Francis, Joshua Reginald, Alsalman, Jameela, Jansens, Hilde, Mahieu, Ludo, Van Rossom, Paul, Vandewal, Wouter, Lepage, Philippe, Blumental, Sophie, Briquet, Caroline, de Louvain, Catholique, Robbrecht, Dirk, Maton, Pierre, Gabriels, Patrick, Rubic, Zana, Kovacevic, Tanja, Nielsen, Jens Peter, Petersen, Jes Reinholdt, Poorisrisak, Porntiva, Jensen, Lise Heilmann, Laan, Mari, Tamm, Eda, Matsinen, Maire, Rummukainen, Maija-Liisa, Gajdos, Vincent, Olivier, Romain, Le Maréchal, Flore, Martinot, Alain, Prot-Labarthe, Sonia, Lorrot, Mathie, Orbach, Daniel, Pagava, Karaman, Hufnagel, Markus, Knuf, Markus, Schlag, Stephanie A. A., Liese, Johannes, Renner, Lorna, Enimil, Anthony, Awunyo, Marah, Syridou, Garyfallia, Spyridis, Nikos, Critselis, Elena, Kouni, Sofia, Mougkou, Katerina, Ladomenou, Fani, Gkentzi, Despoina, Iosifidis, Elias, Roilides, Emmanuel, Sahu, Suneeta, Murki, Srinivas, Malviya, Manoj, Kalavalapalli, Durga Bhavani, Singh, Sanjeev, Singhal, Tanu, Garg, Garima, Garg, Pankaj, Kler, Neelam, Soltani, Jafar, Jafarpour, Zahra, Pouladfar, Gholamreza, Nicolini, Giangiacomo, Montagnani, Carlotta, Galli, Luisa, Esposito, Susanna, Donaʼ, Daniele, Giaquinto, Carlo, Borgia, Eleonora, DʼArgenio, Patrizia, De Luca, Maia, Centenari, Chiara, Raka, Lul, Omar, Abeer, Al-Mousa, Haifaa, Mozgis, Dzintars, Sviestina, Inese, Burokiene, Sigita, Usonis, Vytautas, Tavchioska, Gabriela, Hargadon-Lowe, Antonia, Zarb, Peter, Borg, Michael A., González Lozano, Carlos Agustín, Zárate Castañon, Patricia, Cancino, Martha E., McCullagh, Bernadette, McCorry, Ann, Gormley, Cairine, Al Maskari, Zaina, Al-Jardani, Amina, Pluta, Magdalena, Rodrigues, Fernanda, Brett, Ana, Esteves, Isabel, Marques, Laura, Ali AlAjmi, Jameela, Claudia Cambrea, Simona, Rashed, Asia N., Mubarak Al Azmi, Aeshah Abdu, Chan, Si Min, Isa, Mas Suhaila, Najdenov, Peter, Čižman, Milan, Unuk, Sibila, Finlayson, Heather, Dramowski, Angela, Maté-Cano, Irene, Soto, Beatriz, Calvo, Cristina, Santiago, Begoña, Saavedra-Lozano, Jesus, Bustinza, Amaya, Escosa-García, Luis, Ureta, Noelia, Tagarro, Alfredo, Barrero, Pedro Terol, Rincon-Lopez, Elena Maria, Abubakar, Ismaela, Aston, Jeff, Heginbothom, Maggie, Satodia, Prakash, Garbash, Mehdi, Johnson, Alison, Sharpe, David, Barton, Christopher, Menson, Esse, Arenas-Lopez, Sara, Luck, Suzanne, Doerholt, Katja, McMaster, Paddy, Caldwell, Neil A., Lunn, Andrew, Drysdale, Simon B., Howe, Rachel, Scorrer, Tim, Gahleitner, Florian, Gupta, Richa, Nash, Clare, Alexander, John, Raman, Mala, Bell, Emily, Rajagopal, Veena, Kohlhoff, Stephan, Cox, Elaine, and Zaoutis, Theoklis
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- 2016
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24. Sinus Bradycardia in Children Treated With Remdesivir for COVID-19
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Eleftheriou, Irini, primary, Liaska, Marianthi, additional, Krepis, Panagiotis, additional, Dasoula, Foteini, additional, Dimopoulou, Dimitra, additional, Spyridis, Nikos, additional, and Tsolia, Maria, additional
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- 2021
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25. Real‐life evaluation of a COVID‐19 rapid antigen detection test in hospitalized children
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Eleftheriou, Irini, primary, Dasoula, Foteini, additional, Dimopoulou, Dimitra, additional, Lebessi, Evangelia, additional, Serafi, Eftihia, additional, Spyridis, Nikos, additional, and Tsolia, Maria, additional
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- 2021
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26. Antibiotic prescribing and expenditures in outpatient paediatrics in Greece, 2010–13
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Kourlaba, Georgia, Kourkouni, Eleni, Spyridis, Nikos, Gerber, Jeffrey S., Kopsidas, John, Mougkou, Katerina, Lourida, Athanasia, and Zaoutis, Theoklis E.
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- 2015
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27. Off-label antibiotic use in children in three European countries
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Porta, Alessandro, Esposito, Susanna, Menson, Esse, Spyridis, Nikos, Tsolia, Maria, Sharland, Mike, and Principi, Nicola
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- 2010
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28. Increasing skin infections and Staphylococcus aureus complications in children, England, 1997-2006
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Saxena, Sonia, Thompson, Paula, Birger, Ruthie, Bottle, Alex, Spyridis, Nikos, Wong, Ian, Johnson, Alan P., Gilbert, Ruth, and Sharland, Mike
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Staphylococcus aureus -- Complications and side effects -- Causes of -- Drug therapy ,Infectious skin diseases -- Drug therapy ,Anti-infective agents -- Usage -- Health aspects ,Flucloxacillin -- Usage -- Health aspects ,Health - Abstract
Staphylococcus aureus infection is a leading cause of staphylococcal bacteremia in adults (1) and children (2) in hospitals in the United Kingdom, and recent reports suggest invasive staphylococci are emerging [...]
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- 2010
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29. Treatment with bortezomib-based regimens improves overall response and predicts for survival in patients with primary or secondary plasma cell leukemia: Analysis of the Greek myeloma study group
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Katodritou, Eirini, Terpos, Evangelos, Kelaidi, Charikleia, Kotsopoulou, Maria, Delimpasi, Sossana, Kyrtsonis, Marie-Christine, Symeonidis, Argiris, Giannakoulas, Nikos, Stefanoudaki, Aikaterini, Christoulas, Dimitrios, Chatziaggelidou, Christina, Gastari, Vassiliki, Spyridis, Nikos, Verrou, Evgenia, Konstantinidou, Pavlina, Zervas, Kostas, and Dimopoulos, Meletios A.
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- 2014
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30. The effectiveness of a 9-month regimen of isoniazid alone versus 3- and 4-month regimens of isoniazid plus rifampin for treatment of latent tuberculosis infection in children: results of an 11-year randomized study
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Spyridis, Nikos P., Spyridis, Panayotis G., Gelesme, Anna, Sypsa, Vana, Valianatou, Mina, Metsou, Flora, Gourgiotis, Dimitris, and Tsolia, Maria N.
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Pediatric respiratory diseases -- Demographic aspects ,Pulmonary tuberculosis -- Demographic aspects ,Pulmonary tuberculosis -- Drug therapy ,Isoniazid -- Dosage and administration ,Rifampin -- Dosage and administration ,Drug therapy, Combination -- Methods ,Drug therapy, Combination -- Comparative analysis ,Patient compliance -- Evaluation ,Health ,Health care industry - Published
- 2007
31. The Effect of Age on Whole Blood Interferon-Gamma Release Assay Response among Children Investigated for Latent Tuberculosis Infection
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Critselis, Elena, Amanatidou, Virginia, Syridou, Garyfallia, Spyridis, Nikos P., Mavrikou, Mersini, Papadopoulos, Nikos G., and Tsolia, Maria N.
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- 2012
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32. Comparing neonatal and paediatric antibiotic prescribing between hospitals: a new algorithm to help international benchmarking
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Porta, Alessandro, Hsia, Yingfen, Doerholt, Katja, Spyridis, Nikos, Bielicki, Julia, Menson, Esse, Tsolia, Maria, Esposito, Susanna, Wong, Ian C. K., and Sharland, Mike
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- 2012
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33. MenACWY-TT vaccine for active immunization against invasive meningococcal disease
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Papaevangelou, Vassiliki and Spyridis, Nikos
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- 2012
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34. Eosinophilic leukaemoid reaction and myocardial involvement in a male adolescent withToxocara canisinfection
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Krepis, Panagiotis, primary, Spyridis, Nikos, additional, Maritsi, Despina N, additional, Tsekoura, Vasiliki, additional, and Kossiva, Lydia, additional
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- 2020
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35. The European Union Antibiotic Awareness Day: the paediatric perspective
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Spyridis, Nikos and Sharland, Mike
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- 2008
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36. Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries
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Hsia, Yingfen, Lee, Brian R, Versporten, Ann, Yang, Yonghong, Bielicki, Julia, Jackson, Charlotte, Newland, Jason, Goossens, Herman, Magrini, Nicola, Sharland, Mike, Irwin, Adam, Akula, Akhila, Bamford, Alasdair, Chang, Amanda, da Silva, Andre, Whitelaw, Andrew, Dramowski, Angela, Vasudevan, Anil Kumar, Sharma, Anita, Justicia, Antonio, Chikkappa, Ashok, Slowinska-Jarzabek, Barbara, Rippberger, Bianca, Zhao, Changan, Tersigni, Chiara, Cheng, Chinglan, Harkensee, Christian, Jing, Chuamei, Zhu, Chunmei, Li, Chunyan, Tagliabue, Claudia, Epalza, Cristina, Jacqueline, Daglish, Tian, Daiyin, Jinka, Dasaratha, Gkentzi, Despoina, Dharmapalan, Dhanya, Benadof, Dona, Papadimitriou, Eleni, Iosifidis, Elias, Roilides, Emmanuel, Yarci, Erbu, Majda-Stanisławska, Ewa, Gowin, Ewelina, Chappell, Faye, Torres, Federico Martinon, Collett-White, Francis, Liu, Gang, Lu, Gen, Syrogiannopoulos, George, Pitsava, Georgia, Alvarez-Uria, Gerardo, Renk, Hana, Mahmood, Hana, Saxen, Harri, Finlayson, Heather, Green, Helen, Rabie, Helena, Kandraju, Hemasree, Zhang, Hong, Okokon, Ita, Cross, Jack, Herberg, Jethro, Li, Jianping, Zhang, Jiaosheng, Deng, Jikui, Liu, Jing, Qian, Jing, Yang, Jinhong, Sicińska, Joanna, Hübner, Johannes, Fukuoka, Kahoru, Yao, Kaihu, Cheung, Kaman, Ojeda, Karla, Kaffe, Katerina, Kreitmeyer, Katharina, Doerholt, Katja, Grimwood, Keith, Ledoare, Kirsty, Vazouras, Konstantinos, Shen, Kunling, Tang, Lanfang, Zhang, Lehai, Lin, Li, Ashkenazi-Hoffnung, Liat, Wu, Lijuan, Wang, Lijun, Teston, Lilian, Galli, Luisa, Speirs, Lynne, Tsolia, Maria, Hufnagel, Markus, Knuf, Markus, Duse, Marzia, Ding, Mingjie, Rozic, Mojca, Premru, Mueller, O'Connell, Natasha, Rieber, Nikolaus, Spyridis, Nikos, Tunga, Onkaraiah, Conejo, Pablo Rojo, McMaster, Paddy, Lumbiganon, Pagakrong, Pansa, Paola, D'Argenio, Patrizia, Moriarty, Paul, Nikolic, Petra, Wang, Ping, Paopongsawan, Pongsatorn, Cao, Qing, Deng, Qiulian, Laxminarayan, Ramanan, Kanithi, Ravishankar, Jimenez, Rodolfo, Cao, Sancheng, Singh, Sanjeev, Rees, Sarah, Praveen, Saroey, Kekomaki, Satu, Hackett, Scott, Ashkenazi, Shai, Chang, Si Min, Drysdale, Simon, Koning, Sonia, Subramanian, Sreeram, Murki, Srinivas, Vergnano, Stefania, Gandra, Sumanth, Esposito, Susanna, Anugulruengkitt, Suvaporn, Puthanakit, Thanyawee, Behrends, Uta, Papaevangelous, Vana, Jian, Victoria, Li, Wei, Zhao, Wei, Wang, Wei, Zhang, Wenshuang, Mu, Xiaoping, Dong, Xiaoyie, Jiang, Xiyuan, Chen, Xu, Wang, Yi, Zheng, Yuejie, Horikoshi, Yuho, Aboderin, Aaron, Olayinka, Adebola, Dedeic-Ljubovic, Amela, McCorry, Ann, Enimil, Anthony, Neubert, Antje, solano, antonio, Pignatari, Antonio, Poojary, Aruna, Kambaralieva, Baktygul, McCullagh, Bernadette, Carevi, Biljana, Van Herendael, Bruno, Gormley, Cairine, Carvajal, Camila, Ramírez, Carlos, Fitzgerald, David, Sabuda, Deana, Konopnicki, Deborah, Lacej, Denada, Pierard, Denis, Rios, Edgar, Marshall, Emily, Firre, Eric, van Elzakker, Erika, Shaqiri, Erjona, Darwish Elhajji, Feras, Gawrys, Gerard, Markovic, Goran, Kunsihima, Hiroyuki, Chen, Hui Hiong, Sviestina, Inese, Pristas, Irina, Hoxha, Iris, Korinteli, Irma, Mareković, Ivana, Soltani, Jafar, Labarca, Jaime, AlSalman, Jameela, Horvatic, Jasminka, Frimpong, Juliet Ampomah, Pagava, Karaman, Kei, Kasahara, Okinaka, Keiji, Iregbu, Kenneth, Ghazaryan, Lilit, Raka, Lul, Gessner-Wharton, Mallory, Aldeyab, Mamoon, Cooper, Mandelin, del Castillo, Marcelo, Hojman, Martin, Hudson, Melissa, Alshehri, Mohamed, Ling, Moi Lin, Greer, Nickie, Oduyebo, Oyinlola, Buijtels, Patricia, TEROL BARRERO, PEDRO, Zarb, Peter, Schelstraete, Petra, Nwajiobi-Princewill, Princewill Ifeanyi Philip, Khanna, Priya, Quiros, Rodolfo, Simovic, Sanja, Thompson, Sarah, Chan, Si Min, Burokiene, Sigita, Rachina, Svetlana, Usonis, Vytautas, Cornistein, Wanda, Holemans, Xavier, Gu, Yoshiaki, Brothers, Adam, Hersh, Adam, Fernandez, Alfred, Tribble, Alison, Hurst, Amanda, Green, Andrea, Hammer, Benjamin, Lee, Betty P, Kuzmic, Brenik, Shapiro, Craig, Boge, Craig, Haslam, David, Berman, David, Naeem, Fouzia, Johnson, George, Schwenk, Hayden, Orr, Hillary, Maples, Holly, Olsen, Jared, Gerber, Jeffrey, Girotto, Jennifer, Zweiner, Jennifer, Goldman, Jennifer, Gillon, Jessica, Tansmore, Jessica, Manaloor, John, Courter, Joshua, Mongkolrattanothai, Kanokporn, Patel, Karisma, Merkel, Kathryn, Namtu, Katie, Flett, Kelly, Lee, Kelly, Nichols, Kristen, Klein, Kristin, Handy, Lori, Castagnini, Luis, Mazade, Marc, Heger, Margaret, Fernandez, Marisol, Chang, Michael, Crawford, Michelle, Nelson, Miranda, Bennett, Nicholas, Jaggi, Preeti, Hamdy, Rana, Banerjee, Ritu, Olivero, Rosemary, Patel, Sameer, Arnold, Sandra, Ogrin, Sara, Jones, Sarah, Parker, Sarah, Kubes, Sarah, Hymes, Saul, Weissman, Scott, Chan, Shannon, Henderson, Sheryl, Metjian, Talene, GARPEC and Global-PPS networks, on behalf of the, GARPEC Network, Global-PPS Network, Children's Hospital, HUS Children and Adolescents, and Clinicum
- Subjects
medicine.medical_specialty ,Adolescent ,medicine.drug_class ,030231 tropical medicine ,Antibiotics ,MEDLINE ,Psychological intervention ,CHILDREN ,World Health Organization ,Pediatrics ,Essential medicines ,03 medical and health sciences ,Antimicrobial Stewardship ,0302 clinical medicine ,Antibiotic resistance ,POINT PREVALENCE SURVEY ,SURVEILLANCE ,Medicine and Health Sciences ,Medicine ,Antimicrobial stewardship ,Humans ,030212 general & internal medicine ,Medical prescription ,Child ,Neonatal sepsis ,business.industry ,lcsh:Public aspects of medicine ,STEWARDSHIP ,Infant, Newborn ,Infant ,lcsh:RA1-1270 ,General Medicine ,medicine.disease ,3142 Public health care science, environmental and occupational health ,Drug Utilization ,3. Good health ,Anti-Bacterial Agents ,QUALITY INDICATORS ,Family medicine ,Child, Preschool ,Health Care Surveys ,Human medicine ,business ,Pharmacy Service, Hospital - Abstract
Summary: Background: Improving the quality of hospital antibiotic use is a major goal of WHO's global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally. We aimed to present data on patterns of paediatric AWaRe antibiotic use that could be used for local and national stewardship interventions. Methods: 1-day point prevalence survey antibiotic prescription data were combined from two independent global networks: the Global Antimicrobial Resistance, Prescribing, and Efficacy in Neonates and Children and the Global Point Prevalence Survey on Antimicrobial Consumption and Resistance networks. We included hospital inpatients aged younger than 19 years receiving at least one antibiotic on the day of the survey. The WHO AWaRe classification was used to describe overall antibiotic use as assessed by the variation between use of Access, Watch, and Reserve antibiotics, for neonates and children and for the commonest clinical indications. Findings: Of the 23 572 patients included from 56 countries, 18 305 were children (77·7%) and 5267 were neonates (22·3%). Access antibiotic use in children ranged from 7·8% (China) to 61·2% (Slovenia) of all antibiotic prescriptions. The use of Watch antibiotics in children was highest in Iran (77·3%) and lowest in Finland (23·0%). In neonates, Access antibiotic use was highest in Singapore (100·0%) and lowest in China (24·2%). Reserve antibiotic use was low in all countries. Major differences in clinical syndrome-specific patterns of AWaRe antibiotic use in lower respiratory tract infection and neonatal sepsis were observed between WHO regions and countries. Interpretation: There is substantial global variation in the proportion of AWaRe antibiotics used in hospitalised neonates and children. The AWaRe classification could potentially be used as a simple traffic light metric of appropriate antibiotic use. Future efforts should focus on developing and evaluating paediatric antibiotic stewardship programmes on the basis of the AWaRe index. Funding: GARPEC was funded by the PENTA Foundation. GARPEC-China data collection was funded by the Sanming Project of Medicine in Shenzhen (SZSM2015120330). bioMérieux provided unrestricted funding support for the Global-PPS.
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- 2019
37. High Rates of Prescribing Antimicrobials for Prophylaxis in Children and Neonates: Results From the Antibiotic Resistance and Prescribing in European Children Point Prevalence Survey
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Hufnagel, Markus Versporten, Ann Bielicki, Julia Drapier, Nico Sherland, Mike Goossens, Herman Maria Calle, Graciela and Clark, Julia Cooper, Celia Blyth, Christopher C. and Francis, Joshua Reginald Alsalman, Jameela Jansen, Hilde and Mahieu, Ludo Van Rossom, Paul Vandewal, Wouter Lepage, Philippe Blumental, Sophie Briquet, Caroline Robbrecht, Dirk and Maton, Pierre Gabriels, Patrick Rubic, Zana Kovacevic, Tanja Nielsen, Jens Peter Petersen, Jes Reinholdt and Poorisrisak, Porntiva Jensen, Lise Heilmann Laan, Mari Tamm, Eda Matsinen, Maire Rummukainen, Maija-Liisa Gajdos, Vincent and Olivier, Romain Le Marechal, Flore Martinot, Alain and Dubos, Francois Lagree, Marion Prot-Labarthe, Sonia Lorrot, Mathie Orbach, Daniel Pagava, Karaman Knuf, Markus and Schlag, Stephanie A. A. Liese, Johannes Renner, Lorna and Enimil, Anthony Awunyo, Marah Syridou, Garyfallia Spyridis, Nikos Critselis, Elena Kouni, Sofia Mougkou, Katerina and Ladomenou, Fani Gkentzi, Despoina Iosifidis, Elias Roilides, Emmanuel Sahu, Suneeta Murki, Srinivas Malviya, Manoj and Kalavalapalli, Durga Bhavani Singh, Sanjeev Singhal, Tanu and Garg, Garima Garg, Pankaj Kler, Neelam Soltani, Jafar and Jafarpour, Zahra Pouladfar, Gholamreza Nicolini, Giangiacomo and Montagnani, Carlotta Galli, Luisa Esposito, Susanna Tenconi, Rossana Lo Vecchio, Andrea Dona, Daniele Giaquinto, Carlo and Borgia, Eleonora D'Argenio, Patrizia De Luca, Maia and Centenari, Chiara Raka, Lul Raka, Denis Omar, Abeer and Al-Mousa, Haifaa Mozgis, Dzintars Sviestina, Inese and Burokiene, Sigita Usonis, Vytautas Tavchioska, Gabriela and Hargadon-Lowe, Antonia Zarb, Peter Borg, Michael A. Gonzalez Lozano, Carlos Agustin Zarate Castanon, Patricia Cancino, Martha E. McCullagh, Bernadette McCorry, Ann Gormley, Cairine and Al Maskari, Zaina Al-Jardani, Amina Pluta, Magdalena and Rodrigues, Fernanda Brett, Ana Esteves, Isabel Marques, Laura AlAjmi, Jameela Ali Cambrea, Simona Claudia Rashed, Asia N. Al Azmi, Aeshah Abdu Mubarak Chan, Si Min Isa, Mas Suhaila Najdenov, Peter Cizman, Milan Unuk, Sibila and Finlayson, Heather Dramowski, Angela Mate-Cano, Irene Soto, Beatriz Calvo, Cristina Santiago, Begona Saavedra-Lozano, Jesus Bustinza, Amaya Escosa-Garcia, Luis Ureta, Noelia and Lopez-Varela, Elisa Rojo, Pablo Tagarro, Alfredo Terol Barrero, Pedro Maria Rincon-Lopez, Elena Abubakar, Ismaela and Aston, Jeff Patel, Mitul Russell, Alison Bedford and Heginbothom, Maggie Satodia, Prakash Garbash, Mehdi Johnson, Alison Sharpe, David Barton, Christopher Menson, Esse and Arenas-Lopez, Sara Luck, Suzanne Doerholt, Katja McMaster, Paddy Caldwell, Neil A. Lunn, Andrew Drysdale, Simon B. and Howe, Rachel Scorrer, Tim Gahleitner, Florian Gupta, Richa and Nash, Clare Alexander, John Raman, Mala Bell, Emily and Rajagopal, Veena Kohlhoff, Stephan Cox, Elaine Nichols, Kristen Zaoutis, Theoklis ARPEC Project Grp
- Abstract
Background. This study was conducted to assess the variation in prescription practices for systemic antimicrobial agents used for prophylaxis among pediatric patients hospitalized in 41 countries worldwide. Methods. Using the standardized Antibiotic Resistance and Prescribing in European Children Point Prevalence Survey protocol, a cross-sectional point-prevalence survey was conducted at 226 pediatric hospitals in 41 countries from October 1 to November 30, 2012. Results. Overall, 17 693 pediatric patients were surveyed and 36.7% of them received antibiotics (n = 6499). Of 6818 inpatient children, 2242 (32.9%) received at least 1 antimicrobial for prophylactic use. Of 11 899 prescriptions for antimicrobials, 3400 (28.6%) were provided for prophylactic use. Prophylaxis for medical diseases was the indication in 73.4% of cases (2495 of 3400), whereas 26.6% of prescriptions were for surgical diseases (905 of 3400). In approximately half the cases (48.7% [1656 of 3400]), a combination of 2 or more antimicrobials was prescribed. The use of broad-spectrum antibiotics (BSAs), which included tetracyclines, macrolides, lincosamides, and sulfonamides/trimethoprim, was high (51.8% [1761 of 3400]). Broad-spectrum antibiotic use for medical prophylaxis was more common in Asia (risk ratio [RR], 1.322; 95% confidence interval [CI], 1.202-1.653) and more restricted in Australia (RR, 0.619; 95% CI, 0.521-0.736). Prescription of BSA for surgical prophylaxis also varied according to United Nations region. Finally, a high percentage of surgical patients (79.7% [721 of 905]) received their prophylaxis for longer than 1 day. Conclusions. A high proportion of hospitalized children received prophylactic BSAs. This represents a clear target for quality improvement. Collectively speaking, it is critical to reduce total prophylactic prescribing, BSA use, and prolonged prescription.
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- 2019
38. High rates of prescribing antimicrobials for prophylaxis in children and neonates : results from the antibiotic resistance and prescribing in European children point prevalence survey
- Author
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Hufnagel, Markus, Versporten, Ann, Bielicki, Julia, Drapier, Nico, Sharland, Mike, Goossens, Herman, Sherland, Mike, Maria Calle, Graciela, Clark, Julia, Cooper, Celia, Blyth, Christopher C., Francis, Joshua Reginald, Alsalman, Jameela, Jansen, Hilde, Mahieu, Ludo, Van Rossom, Paul, Vandewal, Wouter, Lepage, Philippe, Blumental, Sophie, Briquet, Caroline, Robbrecht, Dirk, Maton, Pierre, Gabriels, Patrick, Rubic, Zana, Kovacevic, Tanja, Nielsen, Jens Peter, Petersen, Jes Reinholdt, Poorisrisak, Porntiva, Jensen, Lise Heilmann, Laan, Mari, Tamm, Eda, Matsinen, Maire, Rummukainen, Maija-Liisa, Gajdos, Vincent, Olivier, Romain, Le Marechal, Flore, Martinot, Alain, Dubos, Francois, Lagree, Marion, Prot-Labarthe, Sonia, Lorrot, Mathie, Orbach, Daniel, Pagava, Karaman, Knuf, Markus, Schlag, Stephanie A. A., Liese, Johannes, Renner, Lorna, Enimil, Anthony, Awunyo, Marah, Syridou, Garyfallia, Spyridis, Nikos, Critselis, Elena, Kouni, Sofia, Mougkou, Katerina, Ladomenou, Fani, Gkentzi, Despoina, Iosifidis, Elias, Roilides, Emmanuel, Sahu, Suneeta, Murki, Srinivas, Malviya, Manoj, Kalavalapalli, Durga Bhavani, Singh, Sanjeev, Singhal, Tanu, Garg, Garima, Garg, Pankaj, Kler, Neelam, Soltani, Jafar, Jafarpour, Zahra, Pouladfar, Gholamreza, Nicolini, Giangiacomo, Montagnani, Carlotta, Galli, Luisa, Esposito, Susanna, Tenconi, Rossana, Lo Vecchio, Andrea, Dona, Daniele, Giaquinto, Carlo, Borgia, Eleonora, D'Argenio, Patrizia, De Luca, Maia, Centenari, Chiara, Raka, Lul, Raka, Denis, Omar, Abeer, Al-Mousa, Haifaa, Mozgis, Dzintars, Sviestina, Inese, Burokiene, Sigita, Usonis, Vytautas, Tavchioska, Gabriela, Hargadon-Lowe, Antonia, Zarb, Peter, Borg, Michael A., Gonzalez Lozano, Carlos Agustin, Zarate Castanon, Patricia, Cancino, Martha E., McCullagh, Bernadette, McCorry, Ann, Gormley, Cairine, Al Maskari, Zaina, Al-Jardani, Amina, Pluta, Magdalena, Rodrigues, Fernanda, Brett, Ana, Esteves, Isabel, Marques, Laura, AlAjmi, Jameela Ali, Cambrea, Simona Claudia, Rashed, Asia N., Al Azmi, Aeshah Abdu Mubarak, Chan, Si Min, Isa, Mas Suhaila, Najdenov, Peter, Cizman, Milan, Unuk, Sibila, Finlayson, Heather, Dramowski, Angela, Mate-Cano, Irene, Soto, Beatriz, Calvo, Cristina, Santiago, Begona, Saavedra-Lozano, Jesus, Bustinza, Amaya, Escosa-Garcia, Luis, Ureta, Noelia, Lopez-Varela, Elisa, Rojo, Pablo, Tagarro, Alfredo, Terol Barrero, Pedro, Maria Rincon-Lopez, Elena, Abubakar, Ismaela, Aston, Jeff, Patel, Mitul, Russell, Alison Bedford, Heginbothom, Maggie, Satodia, Prakash, Garbash, Mehdi, Johnson, Alison, Sharpe, David, Barton, Christopher, Menson, Esse, Arenas-Lopez, Sara, Luck, Suzanne, Doerholt, Katja, McMaster, Paddy, Caldwell, Neil A., Lunn, Andrew, Drysdale, Simon B., Howe, Rachel, Scorrer, Tim, Gahleitner, Florian, Gupta, Richa, Nash, Clare, Alexander, John, Raman, Mala, Bell, Emily, Rajagopal, Veena, Kohlhoff, Stephan, Cox, Elaine, Nichols, Kristen, Zaoutis, Theoklis, Mahieu, Ludo, and ARPEC Project Grp
- Subjects
antimicrobials ,inpatients ,pediatrics ,point-prevalence survey ,prophylactic prescribing ,Point-prevalence survey ,Male ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Pediatrics ,Drug Prescriptions ,03 medical and health sciences ,Surgical prophylaxis ,0302 clinical medicine ,Pharmacotherapy ,Antibiotic resistance ,Anti-Infective Agents ,030225 pediatrics ,Internal medicine ,medicine ,Prevalence ,Humans ,Medical prescription ,Antimicrobials ,Inpatients ,Prophylactic prescribing ,0303 health sciences ,030306 microbiology ,business.industry ,Pharmacology. Therapy ,Infant, Newborn ,Drug Resistance, Microbial ,General Medicine ,Antibiotic Prophylaxis ,Hospitals, Pediatric ,Prophylactic Surgery ,Drug Utilization ,Anti-Bacterial Agents ,Hospitalization ,Infectious Diseases ,Cross-Sectional Studies ,Relative risk ,Health Care Surveys ,Pediatrics, Perinatology and Child Health ,Chemoprophylaxis ,Drug Therapy, Combination ,Female ,Human medicine ,business ,Child, Hospitalized - Abstract
Background: This study was conducted to assess the variation in prescription practices for systemic antimicrobial agents used for prophylaxis among pediatric patients hospitalized in 41 countries worldwide.Methods: Using the standardized Antibiotic Resistance and Prescribing in European Children Point Prevalence Survey protocol, a cross-sectional point-prevalence survey was conducted at 226 pediatric hospitals in 41 countries from October 1 to November 30, 2012.Results: Overall, 17693 pediatric patients were surveyed and 36.7% of them received antibiotics (n = 6499). Of 6818 inpatient children, 2242 (32.9%) received at least 1 antimicrobial for prophylactic use. Of 11899 prescriptions for antimicrobials, 3400 (28.6%) were provided for prophylactic use. Prophylaxis for medical diseases was the indication in 73.4% of cases (2495 of 3400), whereas 26.6% of prescriptions were for surgical diseases (905 of 3400). In approximately half the cases (48.7% [1656 of 3400]), a combination of 2 or more antimicrobials was prescribed. The use of broad-spectrum antibiotics (BSAs), which included tetracyclines, macrolides, lincosamides, and sulfonamides/trimethoprim, was high (51.8% [1761 of 3400]). Broad-spectrum antibiotic use for medical prophylaxis was more common in Asia (risk ratio [RR], 1.322; 95% confidence interval [CI], 1.202-1.653) and more restricted in Australia (RR, 0.619; 95% CI, 0.521-0.736). Prescription of BSA for surgical prophylaxis also varied according to United Nations region. Finally, a high percentage of surgical patients (79.7% [721 of 905]) received their prophylaxis for longer than 1 day.Conclusions: A high proportion of hospitalized children received prophylactic BSAs. This represents a clear target for quality improvement. Collectively speaking, it is critical to reduce total prophylactic prescribing, BSA use, and prolonged prescription.
- Published
- 2019
39. Leishmaniasis in Cyprus. Retrospective study 2005-2018
- Author
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Makariou, Ioannis, Koliou, Maria, and Spyridis, Nikos
- Published
- 2019
- Full Text
- View/download PDF
40. Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves
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Eleftheriou, Irini, Maritsi, Despina, Lampidi, Stavroula, Charisi, Konstantina, Vantsi, Petrina, Skourti, Kleopatra, Filippatos, Filippos, Amplianitis, Ioannis, Dimou, Despina, Papadopoulou-Legbelou, Kyriaki, Papadopoulou-Alataki, Efimia, Kampouridou, Parthena, Koletsi, Patra, Fotis, Lampros, Vergadi, Elena, Gkentzi, Despoina, Farmaki, Evangelia, Papaevangelou, Vassiliki, Galanakis, Emmanouil, Grivea, Ioanna N., Syrogiannopoulos, George A., Spoulou, Vana, Spyridis, Nikos, Michos, Athanasios, Roilides, Emmanuel, and Tsolia, Maria N.
- Abstract
In this nationwide retrospective study, a substantial decline in the incidence of multisystem inflammatory syndrome in children over 3 successive pandemic waves characterized by different severe acute respiratory syndrome coronavirus 2 variants was documented—from 3.4 of 1000 to 1.1 of 1000 and finally to 0.25 of 1000 confirmed severe acute respiratory syndrome coronavirus 2 positive cases (P< 0.0001), respectively, whereas clinical findings and severity did not significantly vary.
- Published
- 2023
- Full Text
- View/download PDF
41. Risk Factors Associated With Accelerated Rubella IgG Antibody Loss in Previously Vaccinated, Treatment‐Naive Patients With Juvenile Systemic Lupus Erythematosus: A Prospective Study
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Maritsi, Despoina N., primary, Eleftheriou, Irene, additional, Vartzelis, George, additional, Spyridis, Nikos, additional, and Tsolia, Maria N., additional
- Published
- 2019
- Full Text
- View/download PDF
42. An 11-Year-Old Male With Vertebral Osteomyelitis and a Paraspinal Abscess
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Kopsidas, Ioannis, primary, Margariti, Rodanthi, additional, Gavra, Maria, additional, Syngelou, Angeliki, additional, Zambakidis, Christos, additional, Tsolia, Maria, additional, Nikolaidis, Nikolaos, additional, and Spyridis, Nikos, additional
- Published
- 2018
- Full Text
- View/download PDF
43. Epidemiology of infections and antimicrobial use in Greek Neonatal Units
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Gkentzi, Despoina, primary, Kortsalioudaki, Christina, additional, Cailes, Benjamin Campbell, additional, Zaoutis, Theoklis, additional, Kopsidas, John, additional, Tsolia, Maria, additional, Spyridis, Nikos, additional, Siahanidou, Soultana, additional, Sarafidis, Kosmas, additional, Heath, Paul T, additional, and Dimitriou, Gabriel, additional
- Published
- 2018
- Full Text
- View/download PDF
44. Antibody status against measles in previously vaccinated childhood systemic lupus erythematosus patients: a prospective case-control study
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Maritsi, Despoina N, primary, Vartzelis, George, additional, Kopsidas, John, additional, Spyridis, Nikos, additional, and Tsolia, Maria N, additional
- Published
- 2018
- Full Text
- View/download PDF
45. Eosinophilic leukaemoid reaction and myocardial involvement in a male adolescent with Toxocara canis infection.
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Krepis, Panagiotis, Spyridis, Nikos, Maritsi, Despina N, Tsekoura, Vasiliki, and Kossiva, Lydia
- Subjects
- *
HYPEREOSINOPHILIC syndrome , *TEENAGE boys , *TOXOCARA , *CANIS , *PHYSICIANS , *FIBROBLAST growth factor receptors - Abstract
Our patient's symptomatology along with abnormal echocardiogram, elevated cardiac enzymes and severe eosinophilia raised concerns of serious cardiac injury. I Toxocara i spp. infection affects mostly preschool children and is usually asymptomatic; however, it occasionally manifests with profound eosinophilia and even more rarely presents as eosinophilic pseudoleukaemia with potentially life-threatening complications, even among older children and adolescents. Nevertheless, physicians should be aware of the likelihood of steroid-refractory hypereosinophilia following I Toxocara i spp. infection that may imitate hypereosinophilic syndrome and may warrant second-line therapies including hydroxyurea. [Extracted from the article]
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- 2021
- Full Text
- View/download PDF
46. An Infant With Purpuric Rash and Edema
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Argyri, Ioanna Korona, Anastasia Mougkou, Katerina and Vougiouka, Olga Tsolia, Maria Spyridis, Nikos
- Published
- 2015
47. Epidemiology of infections and antimicrobial use in Greek Neonatal Units.
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Gkentzi, Despoina, Kortsalioudaki, Christina, Cailes, Benjamin Campbell, Zaoutis, Theoklis, Kopsidas, John, Tsolia, Maria, Spyridis, Nikos, Siahanidou, Soultana, Sarafidis, Kosmas, Heath, Paul T., Dimitriou, Gabriel, and Neonatal Infection Surveillance Network in Greece
- Subjects
CANDIDEMIA ,EPIDEMIOLOGY ,RESPIRATORY infections ,NEONATAL infections ,STREPTOCOCCUS agalactiae ,COMMUNITY-acquired infections ,ANTI-infective agents ,DRUG utilization statistics ,COMBINATION drug therapy ,COMPARATIVE studies ,CROSS infection ,DRUG resistance in microorganisms ,GESTATIONAL age ,RESEARCH methodology ,MEDICAL cooperation ,MICROBIAL sensitivity tests ,NEONATAL intensive care ,RESEARCH ,EVALUATION research ,NEONATAL intensive care units ,DISEASE incidence ,RETROSPECTIVE studies - Abstract
Objective: To describe the epidemiology of neonatal infections and of antimicrobial use in Greek Neonatal Units (NNUs) in order to develop national, evidence-based guidelines on empiric antimicrobial use for neonatal sepsis in Greece.Design: Retrospective analysis of prospectively collected infection surveillance data from 2012 to 2015, together with a Point Prevalence Survey (PPS) on antimicrobial use and the collection of data on local empiric antimicrobial policies.Setting: 16 NNUs in Greece participating in the neonIN infection surveillance network PATIENTS: Newborns in participating NNUs who had a positive blood, cerebrospinal fluid or urine culture and were treated with at least 5 days of antibiotics.Results: 459 episodes were recorded in 418 infants. The overall incidence of infection was 50/1000 NNU-admissions. The majority of episodes were late-onset sepsis (LOS) (413, 90%). Coagulase-negative Staphylococci (80%) were the most common Gram-positive organisms causing LOS and Klebsiella spp (39%) the most common Gram-negative. Nearly half (45%) of the Klebsiella spp were resistant to at least one aminoglycoside. The PPS revealed that 196 of 484 (40%) neonates were on antimicrobials. The survey revealed wide variation in empiric antimicrobial policies for LOS.Conclusions: This is the largest collection of data on the epidemiology of neonatal infections in Greece and on neonatal antimicrobial use. It provides the background for the development of national evidence-based guidelines. Continuous surveillance, the introduction of antimicrobial stewardship interventions and evidence-based guidelines are urgently required. [ABSTRACT FROM AUTHOR]- Published
- 2019
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- View/download PDF
48. No Survival Improvement for Central Nervous System Multiple Myeloma By the Use of Novel Anti-Myeloma Agents: The Greek Myeloma Study Group Experience
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Katodritou, Eirini, primary, Terpos, Evangelos, additional, Delimpasi, Sosana, additional, Symeonidis, Argiris, additional, Repousis, Panagiotis, additional, Kyrtsonis, Marie-Christine, additional, Michalis, Eurydiki, additional, Papathanasiou, Maria, additional, Polychronidou, Genovefa, additional, Hadjiaggelidou, Christina, additional, Kouraklis, Alexandra, additional, Patsias, Ioannis, additional, Gavriatopoulou, Maria, additional, Kastritis, Efstathios, additional, Kotsopoulou, Maria, additional, Verrou, Evgenia, additional, Gastari, Vassiliki, additional, Giannopoulou, Evlambia, additional, Spyridis, Nikos, additional, Konstantinidou, Pavlina, additional, Pouli, Anastasia, additional, Anagnostopoulos, Achilles, additional, and Dimopoulos, Meletios A., additional
- Published
- 2014
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- View/download PDF
49. Assessment of Hand Hygiene Resources and Practices at the 2 Children’s Hospitals in Greece
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Kouni, Sofia, primary, Kourlaba, Georgia, additional, Mougkou, Katerina, additional, Maroudi, Stefania, additional, Chavela, Betty, additional, Nteli, Chara, additional, Lourida, Athanasia, additional, Spyridis, Nikos, additional, Zaoutis, Theoklis, additional, and Coffin, Susan, additional
- Published
- 2014
- Full Text
- View/download PDF
50. The effectiveness of a 9-month regimen of isoniazid alone versus 3-and 4-month regimens of isoniazid plus rifampin for treatment of latent tuberculosis infection in children: Results of an 11-year Randomized study
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Spyridis, Nikos P. Spyridis, Panayotis G. Gelesme, Anna and Sypsa, Vana Valianatou, Mina Metsou, Flora Gourgiotis, Dimitris Tsolia, Maria N.
- Subjects
bacterial infections and mycoses - Abstract
Background. A 9-month course of isoniazid monotherapy is currently recommended for the treatment of latent tuberculosis infection (LTBI) and has been shown to be effective in both children and adults. Reduced compliance with this regimen has forced physicians to explore shorter regimens. The aim of this study was to compare 3- and 4-month combination regimens of isoniazid plus rifampin with a 9-month regimen of isoniazid monotherapy for the treatment of LTBI in children. Methods. This prospective, randomized, controlled study was conducted over an 11-year period (1995-2005). In period 1 (1995-1998), 232 patients received isoniazid therapy for 9 months ( group A), and 238 patients received isoniazid and rifampin for 4 months (group B). In period 2 (1999-2002), 236 patients were treated with isoniazid and rifampin for 4 months (group C), and 220 patients received the same regimen for 3 months (group D). All patients were observed for >= 3 years. Results. Overall compliance with treatment was good, but patients who received isoniazid monotherapy were less compliant than were those who received short-course combination therapy (, for group A vs. group Pp. 011 B; for group C vs. group D). No patient in any group developed clinical disease during the follow-up Pp. 510 period. New radiographic findings suggestive of possible active disease were more common in patients who received isoniazid monotherapy (24%) than in those treated with shorter regimens (11.8%, 13.6%, and 11% for groups B, C, and D, respectively; for group A vs. group B; for group C vs. group D). Serious drug-related adverse effects were not detected. Conclusions. Short-course treatment with isoniazid and rifampin for 3- 4 months is safe and seems to be superior to a 9-month course of isoniazid monotherapy.
- Published
- 2007
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