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2. Real-time microsensor measurement of local metabolic activities in ex vivo dental biofilms exposed to sucrose and treated with chlorhexidine

Author

von Ohle, Christiane, Gieseke, Armin, Nistico, Laura, Decker, Eva Maria, deBeer, Dirk, and Stoodley, Paul

Subjects
Anti-infective agents -- Chemical properties, Chlorhexidine -- Chemical properties, Microbial mats -- Environmental aspects, Sucrose -- Environmental aspects, Sucrose -- Chemical properties, Mouth -- Microbiology, Mouth -- Research, Biological sciences
Abstract

A study was conducted to examine the metabolic activity like oxygen consumption and acid formation and viability and the effect of antimicrobial chlorhexidine (CHX) treatment on the physiology of the dental biofilms during exposure to sucrose. The CHX exposure was observed to reduce the metabolic activity and microbial viability at the biofilm surface and drove metabolic activity deeper into the biofilm.

Published
2010

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