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5 results on '"Sushama Scalera"'

1. Outcomes after Transplant in Relapsed/Refractory KMT2Ar (MLLr) and mNPM1 (NPM1c) leukemia Patients Achieving Remissions after Menin Inhibition: SNDX-5613 (revumenib) Ph1 Experience

Author

Ghayas C. Issa, Branko Cuglievan, Eytan Stein, Martha L. Arellano, Andrius Žucenka, Nandita Khera, Richard M. Stone, Michael J. Thirman, John F. DiPersio, Nicole Karras, Yu Gu, Rebecca G. Bagley, Galit Rosen, David Tamang, Kimberly Dishman, Sushama Scalera, Michael L. Meyers, Kate Madigan, Nicole McNeer, and Ibrahim Aldoss

Subjects
Immunology, Cell Biology, Hematology, Biochemistry
Published
2022

2. PD21-10 SAFETY AND TOLERABILITY OF AN OXALATE-CONSUMING SYNTHETIC BIOTIC MEDICINE: SYNB8802 IN HEALTHY VOLUNTEERS WITH INDUCED DIETARY HYPEROXALURIA

Author

Caroline B. Kurtz, Richard Riese, Shawn Searle, Aoife M. Brennan, Sushama Scalera, William S. Denney, David Lubkowicz, Andrew Marsh, and Marja K. Puurunen

Subjects
medicine.medical_specialty, business.industry, Urology, Urinary system, urologic and male genital diseases, medicine.disease, Gastroenterology, female genital diseases and pregnancy complications, Oxalate, chemistry.chemical_compound, Tolerability, chemistry, Internal medicine, Healthy volunteers, medicine, Kidney stones, Nephrocalcinosis, Enteric Hyperoxaluria, business, Kidney disease
Abstract

INTRODUCTION AND OBJECTIVE:High urinary oxalate levels (UOx) in patients with enteric hyperoxaluria (EH) can lead to recurrent kidney stones, nephrocalcinosis and chronic kidney disease (CKD). Ther...

Published
2021

3. S1169 Twelve-Month Interim Analysis of Efficacy and Safety of Givosiran, an Investigational RNAi Therapeutic for Acute Hepatic Porphyria, in the ENVISION Open Label Extension

Author

Aneta Ivanova, Peter Stewart, John D. Phillips, Tomohide Adachi, Craig Penz, Samuel M. Silver, Ulrich Stölzel, Amy Simon, Pauline Harper, John J. Ko, Petro E. Petrides, Janneke G. Langendonk, Manisha Balwani, Gayle Ross, Daphne Vassiliou, Shangbin Liu, Herbert L. Bonkovsky, Jerzy Windyga, Charles J. Parker, David C. Rees, Sioban Keel, Jiaan-Der Wang, Karl E. Anderson, D. Montgomery Bissell, Penelope E. Stein, Maria Domenica Cappellini, Sushama Scalera, Paula Aguilera Peiró, David J. Kuter, Laurent Gouya, Paolo Ventura, Susana Monroy, Delia D'Avola, Bruce Ritchie, Yutaka Horie, and Eliane Sardh

Subjects
Acute hepatic porphyria, Oncology, medicine.medical_specialty, Hepatology, RNA interference, business.industry, Internal medicine, Gastroenterology, medicine, Open label, business, Interim analysis
Published
2020

4. Overall Health, Daily Functioning, and Quality of Life in Acute Hepatic Porphyria Patients: ENVISION, a Phase 3 Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Author

Eliane Sardh, Ulrich Stölzel, Gayle Ross, Daphne Vassiliou, Jerzy Windyga, Charles J. Parker, Amy Simon, Sioban Keel, Raili Kauppinen, Craig Penz, T. Lin, Janneke G. Langendonk, Yutaka Horie, Paolo Ventura, Penelope E. Stein, A. Sasapu, Bruce Ritchie, Bruce Wang, Aneta Ivanova, Laurent Gouya, Peter Stewart, John D. Phillips, Delia D'Avola, T. Nakahara, Manisha Balwani, Karl E. Anderson, D.M. Bissell, David C. Rees, P. Aguilera Peiro, Herbert L. Bonkovsky, Pauline Harper, Samuel M. Silver, Jeeyoung Oh, John J. Ko, Jiaan-Der Wang, O. Hother-Nielsen, M.J. Lee, and Sushama Scalera

Subjects
Double blind, Acute hepatic porphyria, Pediatrics, medicine.medical_specialty, Hepatology, Quality of life, business.industry, Gastroenterology, Placebo-controlled study, Medicine, business
Published
2020

5. 996 Disease Characteristics of Acute Hepatic Porphyria Patients: ENVISION, a Phase 3 Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Author

Sushama Scalera, D. Montgomery Bissell, Aneta Ivanova, Peter Stewart, John D. Phillips, Ilja Kubisch, Sioban Keel, Herbert L. Bonkovsky, Yutaka Horie, Laurent Gouya, Jeeyoung Oh, Craig Penz, Ulrich Stölzel, Paolo Ventura, Gayle Ross, Jerzy Windyga, Charles J. Parker, Daphne Vassiliou, Samuel M. Silver, Eliane Sardh, Penelope E. Stein, Karl E. Anderson, John J. Ko, Jiaan-Der Wang, David Coman, Amy Simon, Hung-Chou Kuo, Bruce Wang, Bruce Ritchie, Pauline Harper, Delia D'Avola, Zoe Hua, Elisabeth I. Minder, Manisha Balwani, David C. Rees, Janneke G. Langendonk, Encarna Guillen-Navarro, and Paula Aguilera

Subjects
Acute hepatic porphyria, Double blind, medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, Placebo-controlled study, Disease characteristics, business
Published
2019

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