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Guo Pei,1,2,* Qiong Ou,1,2,* Miaochan Lao,1 Longlong Wang,1 Yanxia Xu,1 Jiaoying Tan,1 Gaihong Zheng1 1Department of Sleep Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, People’s Republic of China; 2School of Medicine, South China University of Technology, Guangzhou, 510006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qiong Ou, Department of Sleep Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, People’s Republic of China, Tel +86-13609717251, Email ouqiong2776@hotmail.comPurpose: This study evaluated the treatment acceptance rate and cost-effectiveness of the telemedicine model in clinical practice for adult patients with obstructive sleep apnea (OSA).Patients and Methods: Patients admitted to the sleep center for snoring were randomly divided into telemedicine and control groups. Patients diagnosed with moderate-to-severe OSA using the Home Sleep Apnea Test (HSAT) were voluntarily treated with auto-adjusted positive airway pressure (APAP) therapy. The acceptance rate of the APAP treatment, cost of patient visits, time cost, and labor cost of doctors in the two groups were observed.Results: A total of 57 subjects were included, with an average age of 40.12± 11.73 years, including 47 males (82.5%); 26 patients were in the telemedicine group, and 31 were in the control group. Follow-up results showed that the acceptance rate of APAP treatment was 57.7% and 54.8% in the telemedicine and control groups, respectively, with no significant difference between the two groups (p=0.829). The cost-benefit analysis showed that the telemedicine group reduced the cost of patients’ medical treatment [− 457.84(− 551.19,1466.87)] but increased the extra intervention frequency and time outside the doctor’s office. Further an

Longlong Wang,1,2 Qiong Ou,1,2 Guangliang Shan,3 Miaochan Lao,2 Guo Pei,2 Yanxia Xu,2 Jinhuan Huang,4 Jiaoying Tan,1,2 Weiping Chen,1,2 Bing Lu1,2 1The Second School of Clinical Medicine, Southern Medical University, Guangzhou, People’s Republic of China; 2Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, People’s Republic of China; 3Department of Epidemiology & Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences/School of Basic Medicine, Peking Union Medical College, Beijing, People’s Republic of China; 4Department of Pulmonary and Critical Care Medicine, People’s Hospital of Chenghai, Shantou, People’s Republic of ChinaCorrespondence: Qiong Ou, Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510080, People’s Republic of China, Tel +86 13609717251, Email ouqiong2776@hotmail.comPurpose: Non-sleepy sleep-disordered breathing (SDB) is increasingly recognized as an important clinical subtype. The association between non-sleepy SDB and cardiovascular disease (CVD) is not well understood. Our objectives were to investigate the relationship between non-sleepy SDB and CVD and determine which nocturnal hypoxia parameter most strongly reflects this association in a large community population.Patients and Methods: Cross-sectional data from 3626 randomly-selected Chinese community-dwelling participants who underwent overnight type IV sleep monitoring were analyzed. Parameters of nocturnal hypoxemia were extracted from sleep monitoring devices, including mean nocturnal oxygen saturation, lowest oxygen saturation, oxygen desaturation index (ODI), and time with oxygen saturation < 90%. An ODI ≥ 7.0 events/h was considered to