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2. Synthesis of 2,4-disubstituted quinazolines promoted by deep eutectic solvent

Author

Rajkumar Romeshkumar Singh, Thokchom Prasanta Singh, Thangjam Linda Devi, Thokchom Jeeta Devi, and Okram Mukherjee Singh

Subjects
Deep eutectic solvent, Quinazoline, Benzyl alcohol, Biodegradable, Chemistry, QD1-999
Abstract

An efficient deep eutectic solvent (DES) promoted reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes (benzoyl alcohols) and ammonium acetate leading to the formation of quinazolines with excellent yields is described. The use of expensive catalysts and organic solvents are avoided in this protocol with the use of DES, which is biodegradable and renewable.

Published
2021
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