1. Ultrasensitive detection of chlortetracycline in animal-origin food using molecularly imprinted electrochemical sensor based on SnS 2 /ZnCo-MOF and AuNPs.
- Author
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Sun R, Han S, Zong W, Chu H, Zhang X, and Jiang H
- Subjects
- Animals, Metal-Organic Frameworks chemistry, Tin Compounds chemistry, Limit of Detection, Sulfides chemistry, Anti-Bacterial Agents analysis, Molecularly Imprinted Polymers chemistry, Zinc analysis, Zinc chemistry, Gold chemistry, Electrochemical Techniques instrumentation, Electrochemical Techniques methods, Metal Nanoparticles chemistry, Molecular Imprinting, Food Contamination analysis, Chlortetracycline analysis
- Abstract
The chlortetracycline (CTC) residue in food poses a threat to human health. Therefore, developing sensitive, convenient and selective analytical methods for CTC detection is crucial. This study innovatively uses tin disulfide/bimetallic organic framework (SnS
2 /ZnCo-MOF) nanocomposites in conjunction with gold nanoparticles (AuNPs) to co-modify a glassy carbon electrode (GCE). Further, a molecularly imprinted polymer (MIP)-based electrochemical sensing platform Au-MIP/SnS2 /ZnCo-MOF/Au/GCE (AZG) was fabricated for selective CTC detection. SnS2 /ZnCo-MOF enhanced the stability and surface area of the AZG sensor. The presence of AuNPs facilitated electron transport between the probe and the electrode across the insulating MIP layer. The fixation of AuNPs and MIP via electropolymerization enhanced the selective recognition of this sensor and amplified its output signal. The AZG sensor demonstrated a wide linear detection range (0.1-100 μM), low detection limit (0.072 nM), and high sensitivity (0.830 μA μM-1 ). It has been used for detecting CTC in animal-origin food with good recovery (96.08%-104.60%)., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023. Published by Elsevier Ltd.)- Published
- 2024
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