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This article is totally based on the literature review about gene expression. Gene is the part of the DNA that is responsible for the formation of the genotype and then a phenotype. Gene can only be expressed in case of formation of protein. The process of the gene expression is accomplished in the two steps; Transcription and translation. Transcription is the process of the formation of the mRNA. Transcription proceeds in the three steps. In initiation step the RNA polymerase moves on the unwind DNA strand until the promoter sequence is reached, next is the elongation step in the newly synthesized RNA strand elongates, the process terminates as the RNA polymerase realize the termination sequence. After the mRNA is formed it is released into the cytoplasm without any alterations in case of prokaryotes, but in case of eukaryotes post transcriptional modifications takes place which include capping, tailing and splicing. Translation is the process of the formation of protein from mRNA. Translation proceeds in the four steps in which the t RNA is charged, the initiation complex is formed with Met-tRNA at the P site start codon is recognized after binding of the ribosomal subunits to mRNA, in elongation step the peptide bond is formed and the polypeptide chain grows, stop codons enters at the A site and thus the process is terminated.

The incidence of urinary stone disease has shown a steep rise in recent decades in all industrialized countries, as did the incidence of obesity, the metabolic syndrome, and type 2 diabetes. Objective: To determine the incidence of nephrolithiasis in diabetic and non-diabetic patients. Methods: A descriptive study was conducted at University of Lahore’s Ultrasound Centre. 300 patients of age group 19 to 85 were enrolled in this study with convenient sampling technique. Out of 300 patients 184 were males and 116 were females and half of them were with the history of diabetes and remaining were normal. Results: Out of 300 patients 150 (50%) patients were with the history of diabetes and 150 (50%) were normal. 184 (61.3%) males and 116 (38.7%) females were enrolled in this study. Out of 300 patients 177(59.0%) patients were obese and 113 (41%) were normal. In this study different age groups were selected. Mean ± SD value of age was 40.796 ± 16.110. Out of 150 diabetic patients, 120 (80.0%) were diagnosed with renal stones. Conclusions: It is concluded that the patients with the history of diabetes are more likely to develop kidneys stones as compared to non-diabetic patients. Males are more likely to develop kidney stones than females

In this paper, we introduce two new subclasses of p-valent spirallike functions of order α:We prove necessary and suffcient conditions for these newly defined classes and also point out someknown consequences of our results.

This study investigated video game based academic and information literacy (IL) learning of teenagers of private schools of Lahore city. Lahore is one of the big city and knowledge hub of Pakistan. Previous literature highlighted the importance of video games in learning academic and IL skills; therefore, the present study aims to reveal this fact in local context. The presented study adopted qualitative research approach and utilized phenomenological research method to achieve its objectives. The data was collected through interviews. The study participants were teenagers (13 to 19 years) of elite economic class private schools who were frequent video game players. Based on the study findings, it can be concluded that playing video games has positive impact on teenagers' learning. The majority of the participants were of view that challenges of completing various stages of games and interacting with online competitors enhanced their social (communication) and information literacy (searching/locating and evaluating) skills. The results of the study are benefitted for the game developers, teachers, librarians and parents.