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Introduction. Primary sarcomas are uncommonly seen in the larynx and comprise around 1% of all laryngeal malignant tumors. We present three cases of patients with different types of laryngeal sarcomas and discuss about diagnostic and treatment difficulties. Case outline. Each patient presented with hoarseness and shortness of breath. Computed tomography scans showed large transglottic tumors of the larynx with no signs of cervical lymphadenopathy and definitive diagnoses of sarcomas were made by pathologists. Each patient underwent total laryngectomy with clear resection margins. Patient with laryngeal leiomyosarcoma developed large locoregional relapse of malignant disease and pulmonary metastasis four months after surgery and patient with laryngeal osteosarcoma was diagnosed with inoperative locoregional relapse of malignant disease three months after surgery. Both patients died within six months after surgery. On the other hand, patient with laryngeal chondrosarcoma was disease-free during the three-year follow-up. Conclusion. Primary laryngeal sarcomas have low incidence and they differ from squamous cell carcinoma by their biological characteristics and behavior. Radical surgical resection remains the mainstay of treatment with uncertain outcome due to their high potential for recurrence or metastatic spread.

Background/Aim. Eustachian tube is a connection between throat and the middle ear. Inflammatory processes and malformations of nasal cavity could lead to dysfunction of the whole upper respiratory tract, this emphasizing the evaluation of the Eustachian tube function both in surgery and in medicine in general. The aim of this study was to evaluate the Eustachian tube passage and function by tympanometry in different types of nasal resistance. Methods. Eustachian tube passage and function was tested in 102 patients with different types of nasal pathology and nasal resistance and compared to the results of 41 healthy persons with normal values of nasal resistance included in the control group. The patients with nasal pathology were divided into three subgroups: with mechanical, inflammatory and mixed alterations. Nasal resistance was carried out with constant body plethysmography (Jaeger). The test of Eustachian tube passage and function was performed using tympanometric Toynbee-deglutition/Valsalva-deglutition test. The results of measurements were compared with those in the healthy control group and analyzed by means of parametric and nonparametric statistic tests, Pearson χ2 test, Fisher test of exact probability and variance analysis. Results. The subgroup with inflammatory alterations had significantly higher values of pathological tympanograms than other subgroups and the control group (p < 0,05). The dysfunction of the Eustachian tube was significantly more present in all subgroups than in the control group (p < 0,05). Conclusion. Pathological form of tympanograms is more often present in purely inflammatory changes of nasal cavities with higher nasal resistance than in mechanical nasal obstruction. All forms of higher nasal resistance are more often accompanied with Eustachian tube dysfunction. There was no significant differences in Eustachian tube passage between the subgroups and the control group.

Background/Aim. Eustachan tube is a connection between throat and the middle ear. Inflammatory processes and malformations of nasal cavity could lead to dysfunction of the whole upper respiratory tract, thas emphasizing the evaluation of the Eustachian tube function both in surgery and in medicine in general. The aim of this study was to evaluate the Eustachian tube passage and function by tympanometry in different types of nasal resistance. Methods. Eustachian tube passage and function was tested in 102 patients with different types of nasal pathology and nasal resistance and compared to the results of 41 healthy persons with normal values of nasal resistance included in the control group. The patients with nasal pathology were divided into three subgroups: with mechanical, inflammatory and mixed alterations. Nasal resistance was carried out with constant body plethysmography (Jaeger). The test of Eustachian tube passage and function was performed using tympanometric Toynbee-deglutition/Valsalva-deglutition test. The results of measurements were compared with those in the healthy control group and analyzed by means of parametric and nonparametric statistic tests, Pearson χsup2; test, Fisher test of exact probability and variance analysis. Results. The subgroup with inflammatory alterations had significantly higher values of pathological tympanograms than other subgroups and the control group (p < 0,05). The dysfunction of the Eustachian tube was significantly more present in all subgroups than in the control group (p < 0,05). Conclusion. Pathological form of tympanograms is more often present in purely inflammatory changes of nasal cavities with higher nasal resistance than in mechanical nasal obstruction. All forms of higher nasal resistance are more often accompanied with Eustachian tube dysfunction. There was no significant differences in Eustachian tube passage between the subgroups and the control group. [ABSTRACT FROM AUTHOR]

Background/aim: Eustachan tube is a connection between throat and the middle ear. Inflammatory processes and malformations of nasal cavity could lead to dysfunction of the whole upper respiratory tract, thas emphasizing the evaluation of the Eustachian tube function both in surgery and in medicine in general. The aim of this study was to evaluate the Eustachian tube passage and function by tympanometry in different types of nasal resistance., Methods: Eustachian tube passage and function was tested in 102 patients with different types of nasal pathology and nasal resistance and compared to the results of 41 healthy persons with normal values of nasal resistance included in the control group. The patients with nasal pathology were divided into three subgroups: with mechanical, inflammatory and mixed alterations. Nasal resistance was carried out with constant body plethysmography (Jaeger). The test of Eustachian tube passage and function was performed using tympanometric Toynbee-deglutition/Valsalva-deglutition test. The results of measurements were compared with those in the healthy control group and analyzed by means of parametric and nonparametric statistic tests, Pearson chi2 test, Fisher test of exact probability and variance analysis., Results: The subgroup with inflammatory alterations had significantly higher values of pathological tympanograms than other subgroups and the control group (p < 0,05). The dysfunction of the Eustachian tube was significantly more present in all subgroups than in the control group (p < 0,05)., Conclusion: Pathological form of tympanograms is more often present in purely inflammatory changes of nasal cavities with higher nasal resistance than in mechanical nasal obstruction. All forms of higher nasal resistance are more often accompanied with Eustachian tube dysfunction. There was no significant differences in Eustachian tube passage between the subgroups and the control group.