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304 results on '"Van Scoyk A"'

1. Gene expression-based modeling of overall survival in Black or African American patients with lung adenocarcinoma

Author

Bin Zhu, Stephanie S. McHale, Michelle Van Scoyk, Gregory Riddick, Pei-Ying Wu, Chu-Fang Chou, Ching-Yi Chen, and Robert A. Winn

Subjects
lung adenocarcinoma, race disparity, African American, immune response, machine learning, overall survival, Immunologic diseases. Allergy, RC581-607
Abstract

IntroductionLung cancer is a leading cause of cancer-related deaths worldwide. Black/African American (B/AA) populations, in particular, exhibit the highest incidence and mortality rates of lung adenocarcinoma (LUAD) in the United States.MethodsThis study aims to explore gene expression patterns linked to LUAD in B/AA and case-matched white patients, with the goal of developing predictive models for prognosis. Leveraging RNA sequencing data from The Cancer Genome Atlas (TCGA) database, genes and pathways associated with overall survival (OS) were identified.ResultsThe OS-associated genes in B/AA patients were distinct from those in white patients, showing predominant enrichment in immune-related pathways. Furthermore, mRNA co-expression network analysis revealed that OS-associated genes in B/AA patients had higher levels of interaction with various pathways, including those related to immunity, cell-ECM interaction, and specific intracellular signaling pathways. Notably, a potential B/AA-specific biomarker, C9orf64, demonstrated significant correlations with genes involved in immune response. Unsupervised machine learning algorithms stratified B/AA patients into groups with distinct survival outcomes, while supervised algorithms demonstrated a higher accuracy in predicting survival for B/AA LUAD patients compared to white patients.DiscussionIn total, this study explored OS-associated genes and pathways specific for B/AA LUAD patients. Further validation and clinical application of these findings are warranted to address disparities and improve outcomes in diverse patient populations.

Published
2024
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3. Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men

Author

Wu, Pei-Ying, Van Scoyk, Michelle, McHale, Stephanie S., Chou, Chu-Fang, Riddick, Gregory, Farouq, Kamran, Hu, Bin, Kraskauskiene, Vita, Koblinski, Jennifer, Lyons, Charles, Rijal, Arjun, Vudatha, Vignesh, Zhang, Dongyu, Trevino, Jose G., Shah, Rachit D., Nana-Sinkam, Patrick, Huang, Yong, Ma, Shwu-Fan, Noth, Imre, Hughes-Halbert, Chanita, Seewaldt, Victoria L., Chen, Ching-Yi, and Winn, Robert A.

Published
2024
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9. Mutation and cell state compatibility is required and targetable in Ph+ acute lymphoblastic leukemia minimal residual disease

Author

Winter, Peter S., primary, Ramseier, Michelle L., additional, Navia, Andrew W., additional, Saksena, Sachit, additional, Strouf, Haley, additional, Senhaji, Nezha, additional, DenAdel, Alan, additional, Mirza, Mahnoor, additional, An, Hyun Hwan, additional, Bilal, Laura, additional, Dennis, Peter, additional, Leahy, Catharine S., additional, Shigemori, Kay, additional, Galvez-Reyes, Jennyfer, additional, Zhang, Ye, additional, Powers, Foster, additional, Mulugeta, Nolawit, additional, Gupta, Alejandro J., additional, Calistri, Nicholas, additional, Van Scoyk, Alex, additional, Jones, Kristen, additional, Liu, Huiyun, additional, Stevenson, Kristen E., additional, Ren, Siyang, additional, Luskin, Marlise R., additional, Couturier, Charles P., additional, Amini, Ava P., additional, Raghavan, Srivatsan, additional, Kimmerling, Robert J., additional, Stevens, Mark M., additional, Crawford, Lorin, additional, Weinstock, David M., additional, Manalis, Scott R., additional, Shalek, Alex K., additional, and Murakami, Mark A., additional

Published
2024
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11. Gene expression-based modeling of overall survival in Black or African American patients with lung adenocarcinoma.

Author

Zhu, Bin, McHale, Stephanie S., Van Scoyk, Michelle, Riddick, Gregory, Wu, Pei-Ying, Chou, Chu-Fang, Chen, Ching-Yi, and Winn, Robert A.

Subjects
MACHINE learning, GENE expression, OVERALL survival, SURVIVAL rate, RACE
Abstract

Introduction: Lung cancer is a leading cause of cancer-related deaths worldwide. Black/African American (B/AA) populations, in particular, exhibit the highest incidence and mortality rates of lung adenocarcinoma (LUAD) in the United States. Methods: This study aims to explore gene expression patterns linked to LUAD in B/AA and case-matched white patients, with the goal of developing predictive models for prognosis. Leveraging RNA sequencing data from The Cancer Genome Atlas (TCGA) database, genes and pathways associated with overall survival (OS) were identified. Results: The OS-associated genes in B/AA patients were distinct from those in white patients, showing predominant enrichment in immune-related pathways. Furthermore, mRNA co-expression network analysis revealed that OS-associated genes in B/AA patients had higher levels of interaction with various pathways, including those related to immunity, cell-ECM interaction, and specific intracellular signaling pathways. Notably, a potential B/AA-specific biomarker, C9orf64 , demonstrated significant correlations with genes involved in immune response. Unsupervised machine learning algorithms stratified B/AA patients into groups with distinct survival outcomes, while supervised algorithms demonstrated a higher accuracy in predicting survival for B/AA LUAD patients compared to white patients. Discussion: In total, this study explored OS-associated genes and pathways specific for B/AA LUAD patients. Further validation and clinical application of these findings are warranted to address disparities and improve outcomes in diverse patient populations. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Parp3 promotes long-range end joining in murine cells

Author

Layer, Jacob V., Cleary, J. Patrick, Brown, Alexander J., Stevenson, Kristen E., Morrow, Sara N., Van Scoyk, Alexandria, Blasco, Rafael B., Karaca, Elif, Meng, Fei-Long, Frock, Richard L., Tivey, Trevor, Kim, Sunhee, Fuchs, Hailey, Chiarle, Roberto, Alt, Frederick W., Roberts, Steven A., Weinstock, David M., and Day, Tovah A.

Published
2018

16. Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1

Author

Jing Yang, Edith A. Perez, Changchun Hou, Pin Zhang, Michelle Van Scoyk, Robert A. Winn, Lijun Rong, and Jing Liu

Subjects
COVID-19, SARS-CoV-2 receptor ACE2, transcriptional regulation, COPD, chromatin immunoprecipitation, Immunologic diseases. Allergy, RC581-607
Abstract

Multiple lines of evidence have demonstrated that cigarette smoke or Chronic Obstructive Pulmonary Disease upregulates angiotensin-converting enzyme 2, the cellular receptor for the entry of the severe acute respiratory syndrome coronavirus 2, which predisposes individuals to develop severe Coronavirus disease 2019. The reason for this observation is unknown. We recently reported that the loss of function of Miz1 in the lung epithelium in mice leads to a spontaneous COPD-like phenotype, associated with upregulation of angiotensin-converting enzyme 2. We also reported that cigarette smoke exposure downregulates Miz1 in lung epithelial cells and in mice, and Miz1 is also downregulated in the lungs of COPD patients. Here, we provide further evidence that Miz1 directly binds to and represses the promoter of angiotensin-converting enzyme 2 in mouse and human lung epithelial cells. Our data provide a potential molecular mechanism for the upregulation of angiotensin-converting enzyme 2 observed in smokers and COPD patients, with implication in severe Coronavirus disease 2019.

Published
2021
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18. Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models

Author

Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie, Mahmoud Ghandi, Neekesh V. Dharia, Joshua Dempster, Mark Murakami, Kay Shigemori, Sara N. Morrow, Alexandria Van Scoyk, Nicolas A. Cordero, Kristen E. Stevenson, Maneka Puligandla, Brian Haas, Christopher Lo, Robin Meyers, Galen Gao, Andrew Cherniack, Abner Louissaint, Valentina Nardi, Aaron R. Thorner, Henry Long, Xintao Qiu, Elizabeth A. Morgan, David M. Dorfman, Danilo Fiore, Julie Jang, Alan L. Epstein, Ahmet Dogan, Yanming Zhang, Steven M. Horwitz, Eric D. Jacobsen, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, D. Allen Annis, Manuel Aivado, Mansoor N. Saleh, Amitkumar Mehta, Aviad Tsherniak, David Root, Francisca Vazquez, William C. Hahn, Giorgio Inghirami, Jon C. Aster, David M. Weinstock, and Raphael Koch

Subjects
Science
Abstract

T- and NK-cell lymphomas (TCL) are a group of lymphoid malignancies characterized by poor prognosis, but the absence of appropriate pre-clinical models has hampered the development of effective therapies. Here the authors establish several pre-clinical models and identify vulnerabilities that could be further exploited to treat patients afflicted by these diseases.

Published
2018
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21. P324: CELL PLASTICITY PREDETERMINES TREATMENT RESPONSE IN T-ALL

Author

Dimitrova, Valeriya, primary, Frede, Julia, additional, Montanaro, Anna, additional, Potdar, Sayalee, additional, Stuart, Hannah, additional, Sotoudeh, Noori, additional, Van Scoyk, Alexandria, additional, Bhatt, Shruti, additional, Letai, Anthony, additional, Aster, Jon, additional, Lohr, Jens, additional, and Knoechel, Birgit, additional

Published
2023
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22. Supplementary Figures from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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23. Supplementary Table 1 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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24. Supplementary Table 8 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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25. Supplementary Table 5 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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26. Supplementary Table 3 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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27. Supplementary Table 7 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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28. Data from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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29. Supplementary Table 6 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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31. Supplementary Table 4 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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32. Supplementary Table 2 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Yan, Dongqing, primary, Franzini, Anca, primary, Pomicter, Anthony D., primary, Halverson, Brayden J., primary, Antelope, Orlando, primary, Mason, Clinton C., primary, Ahmann, Jonathan M., primary, Senina, Anna V., primary, Vellore, Nadeem A., primary, Jones, Courtney L., primary, Zabriskie, Matthew S., primary, Than, Hein, primary, Xiao, Michael J., primary, van Scoyk, Alexandria, primary, Patel, Ami B., primary, Clair, Phillip M., primary, Heaton, William L., primary, Owen, Shawn C., primary, Andersen, Joshua L., primary, Egbert, Christina M., primary, Reisz, Julie A., primary, D'Alessandro, Angelo, primary, Cox, James E., primary, Gantz, Kevin C., primary, Redwine, Hannah M., primary, Iyer, Siddharth M., primary, Khorashad, Jamshid S., primary, Rajabi, Nima, primary, Olsen, Christian A., primary, O'Hare, Thomas, primary, and Deininger, Michael W., primary

Published
2023
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33. Supplementary Table 2 from PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages

Author

Avasarala, Sreedevi, primary, Wu, Pei-Ying, primary, Khan, Samia Q., primary, Yanlin, Su, primary, Van Scoyk, Michelle, primary, Bao, Jianqiang, primary, Di Lorenzo, Alessandra, primary, David, Odile, primary, Bedford, Mark T., primary, Gupta, Vineet, primary, Winn, Robert A., primary, and Bikkavilli, Rama Kamesh, primary

Published
2023
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34. Supplementary Table 5 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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35. Supplementary Table 4 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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36. Supplementary Table 2 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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37. Data from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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38. Supplementary Table 1 from PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages

Author

Avasarala, Sreedevi, primary, Wu, Pei-Ying, primary, Khan, Samia Q., primary, Yanlin, Su, primary, Van Scoyk, Michelle, primary, Bao, Jianqiang, primary, Di Lorenzo, Alessandra, primary, David, Odile, primary, Bedford, Mark T., primary, Gupta, Vineet, primary, Winn, Robert A., primary, and Bikkavilli, Rama Kamesh, primary

Published
2023
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39. Supplementary Table 6 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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40. Supplementary Table 3 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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42. Supplementary Table 7 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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43. Supplementary Table 1 from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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44. Supplementary Figures and Methods from Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Author

Lossos, Chen, primary, Liu, Yunpeng, primary, Kolb, Kellie E., primary, Christie, Amanda L., primary, Van Scoyk, Alexandria, primary, Prakadan, Sanjay M., primary, Shigemori, Kay, primary, Stevenson, Kristen E., primary, Morrow, Sara, primary, Plana, Olivia D., primary, Fraser, Cameron, primary, Jones, Kristen L., primary, Liu, Huiyun, primary, Pallasch, Christian P., primary, Modiste, Rebecca, primary, Nguyen, Quang-De, primary, Craig, Jeffrey W., primary, Morgan, Elizabeth A., primary, Vega, Francisco, primary, Aster, Jon C., primary, Sarosiek, Kristopher A., primary, Shalek, Alex K., primary, Hemann, Michael T., primary, and Weinstock, David M., primary

Published
2023
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45. Supplementary Figure 1 from PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages

Author

Avasarala, Sreedevi, primary, Wu, Pei-Ying, primary, Khan, Samia Q., primary, Yanlin, Su, primary, Van Scoyk, Michelle, primary, Bao, Jianqiang, primary, Di Lorenzo, Alessandra, primary, David, Odile, primary, Bedford, Mark T., primary, Gupta, Vineet, primary, Winn, Robert A., primary, and Bikkavilli, Rama Kamesh, primary

Published
2023
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48. Supplementary Table 4 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Michael W. Deininger, Thomas O'Hare, Christian A. Olsen, Nima Rajabi, Jamshid S. Khorashad, Siddharth M. Iyer, Hannah M. Redwine, Kevin C. Gantz, James E. Cox, Angelo D'Alessandro, Julie A. Reisz, Christina M. Egbert, Joshua L. Andersen, Shawn C. Owen, William L. Heaton, Phillip M. Clair, Ami B. Patel, Alexandria van Scoyk, Michael J. Xiao, Hein Than, Matthew S. Zabriskie, Courtney L. Jones, Nadeem A. Vellore, Anna V. Senina, Jonathan M. Ahmann, Clinton C. Mason, Orlando Antelope, Brayden J. Halverson, Anthony D. Pomicter, Anca Franzini, and Dongqing Yan

Abstract

Next generation sequencing for 52 myeloid malignancies-related genes.

Published
2023
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49. Supplementary Table 5 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Michael W. Deininger, Thomas O'Hare, Christian A. Olsen, Nima Rajabi, Jamshid S. Khorashad, Siddharth M. Iyer, Hannah M. Redwine, Kevin C. Gantz, James E. Cox, Angelo D'Alessandro, Julie A. Reisz, Christina M. Egbert, Joshua L. Andersen, Shawn C. Owen, William L. Heaton, Phillip M. Clair, Ami B. Patel, Alexandria van Scoyk, Michael J. Xiao, Hein Than, Matthew S. Zabriskie, Courtney L. Jones, Nadeem A. Vellore, Anna V. Senina, Jonathan M. Ahmann, Clinton C. Mason, Orlando Antelope, Brayden J. Halverson, Anthony D. Pomicter, Anca Franzini, and Dongqing Yan

Abstract

The 1,287 genes targeted by the shRNA of the leukemia library.

Published
2023
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50. Supplementary Table 3 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

Author

Michael W. Deininger, Thomas O'Hare, Christian A. Olsen, Nima Rajabi, Jamshid S. Khorashad, Siddharth M. Iyer, Hannah M. Redwine, Kevin C. Gantz, James E. Cox, Angelo D'Alessandro, Julie A. Reisz, Christina M. Egbert, Joshua L. Andersen, Shawn C. Owen, William L. Heaton, Phillip M. Clair, Ami B. Patel, Alexandria van Scoyk, Michael J. Xiao, Hein Than, Matthew S. Zabriskie, Courtney L. Jones, Nadeem A. Vellore, Anna V. Senina, Jonathan M. Ahmann, Clinton C. Mason, Orlando Antelope, Brayden J. Halverson, Anthony D. Pomicter, Anca Franzini, and Dongqing Yan

Abstract

Standard hematologic parameters in SIRT5-/- mice and SIRT5+/+ littermates.

Published
2023
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