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11 results on '"Vancraeynest J"'

3. $\beta$ decay of $^{40}Ti$

Author

Liu, W, Hellström, M, Collatz, R, Benlliure, J, Chulkov, L V, Cortina-Gil, D, Farget, F, Grawe, H, Hu, Z, Iwasa, N, Pfützner, M, Piechaczek, A, Raabe, R, Reusen, I, Roeckl, E, Vancraeynest, J, and Wöhr, A

Subjects
Nuclear Physics
Published
1997

10. The MIDA Mortality Risk Score: development and external validation of a prognostic model for early and late death in degenerative mitral regurgitation

Author

Hector I. Michelena, Mida Investigators, Rakesh M. Suri, Francesco Grigioni, Letizia Bacchi-Reggiani, Alexis Theron, Gaetano Gargiulo, Vuyisile T. Nkomo, Marie-Annick Clavel, Siham Lazam, Martin Schumacher, Jean-François Avierinos, Andrea Barbieri, Jean-Louis Vanoverschelde, Maurice Enriquez-Sarano, Agnes Pasquet, Catherine Szymanski, Pablo Oberti, Christophe Tribouilloy, Rodolfo Pizarro, Marianne Huebner, Dan Rusinaru, Francesca Bursi, DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE, Facolta' di MEDICINA e CHIRURGIA, AREA MIN. 06 - Scienze mediche, Grigioni, Francesco, Clavel, Marie-Annick, Vanoverschelde, Jean-Loui, Tribouilloy, Christophe, Pizarro, Rodolfo, Huebner, Marianne, Avierinos, Jean-Francoi, Barbieri, Andrea, Suri, Rakesh, Pasquet, Agné, Rusinaru, Dan, Gargiulo, Gaetano D, Oberti, Pablo, Théron, Alexi, Bursi, Francesca, Michelena, Hector, Lazam, Siham, Szymanski, Catherine, Nkomo, Vuyisile T, Schumacher, Martin, Bacchi-Reggiani, Letizia, Enriquez-Sarano, Maurice, University of Bologna/Università di Bologna, Mayo Clinic [Rochester], Pôle d’Imagerie Médicale, Radiothérapie et Oncologie (MIRO), Université Catholique de Louvain = Catholic University of Louvain (UCL), Pôle de Recherche Cardiovasculaire (CARD), Institut de Recherche Expérimentale et Clinique (IREC), Division of Cardiology, Cliniques Universitaires Saint-Luc [Bruxelles], CHU Amiens-Picardie, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Assistance Publique - Hôpitaux de Marseille (APHM), IRPPS-CNR, Salerno, Università degli Studi di Salerno = University of Salerno (UNISA), Mécanismes physiologiques et conséquences des calcifications cardiovasculaires: rôle des remodelages cardiovasculaires et osseux, Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Cardiologie [Amiens], Aix Marseille Université (AMU), Mayo Clinic [Rochester, MN, USA], and MIDA Investigators: C Tribouilloy, F Trojette, C Szymanski, D Rusinaru, G Touati, J P Remadi, F Grigioni, A Russo, E Biagini, F Pasquale, M Ferlito, C Rapezzi, C Savini, G Marinelli, D Pacini, G D Gargiulo, R Di Bartolomeo, I Corazza, P Oberti, R Pizarro, J Boulif, C de Meester, G El Khoury, B Gerber, S Lazam, A Pasquet, P Noirhomme, D Vancraeynest, J-L Vanoverschelde, J F Avierinos, F Collard, A Théron, G Habib, A Barbieri, F Bursi, F Mantovani, R Lugli, M G Modena, G Boriani, M A Clavel, J Maalouf, H Michelena, Vuyisile T Nkomo, M Enriquez-Sarano, R Suri, L Bacchi-Reggiani, M Schumacher, M Huebner

Subjects
Male, medicine.medical_specialty, Databases, Factual, Prognosi, [SDV]Life Sciences [q-bio], Concordance, Population, Clinical Decision-Making, MEDLINE, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Internal medicine, Atrial Fibrillation, medicine, Humans, 030212 general & internal medicine, Registries, education, Mitral regurgitation, Aged, education.field_of_study, Framingham Risk Score, business.industry, Mitral repair, Mitral Valve Insufficiency, Percutaneous mitral repair, Percutaneous mitral replacement, Prognosis, Surgery, Middle Aged, Clinical trial, Echocardiography, Predictive value of tests, embryonic structures, Cohort, Mitral Valve, Female, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies
Abstract

International audience; Aims In degenerative mitral regurgitation (DMR), lack of mortality scores predicting death favours misperception of individual patients' risk and inappropriate decision-making. Methods and results The Mitral Regurgitation International Database (MIDA) registries include 3666 patients (age 66 +/- 14 years; 70% males; follow-up 7.8 +/- 5.0 years) with pure, isolated, DMR consecutively diagnosed by echocardiography at tertiary (European/North/South-American) centres. The MIDA Score was derived from the MIDA-Flail-Registry (2472 patients with DMR and flail leaflet-Derivation Cohort) by weighting all guideline-provided prognostic markers, and externally validated in the MIDA-BNP-Registry (1194 patients with DMR and flail leaflet/prolapse-Validation Cohort). The MIDA Score ranged from 0 to 12 depending on accumulating risk factors. In predicting total mortality post-diagnosis, the MIDA Score showed excellent concordance both in Derivation Cohort (c = 0.78) and Validation Cohort (c = 0.81). In the whole MIDA population (n = 3666 patients), 1-year mortality with Scores 0, 7-8, and 11-12 was 0.4, 17, and 48% under medical management and 1, 7, and 14% after surgery, respectively (P < 0.001). Five-year survival with Scores 0, 7-8, and 11-12 was 98 +/- 1, 57 +/- 4, and 21 +/- 10% under medical management and 99 +/- 1, 82 +/- 2, and 57 +/- 9% after surgery (P < 0.001). In models including all guideline-provided prognostic markers and the EuroScoreII, the MIDA Score provided incremental prognostic information (P

Published
2016
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11. Glia-neuron interactions underlie state transitions to generalized seizures.

Author

Diaz Verdugo C, Myren-Svelstad S, Aydin E, Van Hoeymissen E, Deneubourg C, Vanderhaeghe S, Vancraeynest J, Pelgrims R, Cosacak MI, Muto A, Kizil C, Kawakami K, Jurisch-Yaksi N, and Yaksi E

Subjects
Animals, Animals, Genetically Modified, Brain cytology, Brain diagnostic imaging, Disease Models, Animal, Gap Junctions physiology, Glutamic Acid metabolism, Humans, Microscopy, Confocal, Nerve Net cytology, Nerve Net physiopathology, Neuroglia physiology, Neurons physiology, Optical Imaging, Optogenetics, Patch-Clamp Techniques, Zebrafish, Brain physiopathology, Cell Communication, Cortical Excitability physiology, Epilepsy physiopathology, Seizures physiopathology
Abstract

Brain activity and connectivity alter drastically during epileptic seizures. The brain networks shift from a balanced resting state to a hyperactive and hypersynchronous state. It is, however, less clear which mechanisms underlie the state transitions. By studying neural and glial activity in zebrafish models of epileptic seizures, we observe striking differences between these networks. During the preictal period, neurons display a small increase in synchronous activity only locally, while the gap-junction-coupled glial network was highly active and strongly synchronized across large distances. The transition from a preictal state to a generalized seizure leads to an abrupt increase in neural activity and connectivity, which is accompanied by a strong alteration in glia-neuron interactions and a massive increase in extracellular glutamate. Optogenetic activation of glia excites nearby neurons through the action of glutamate and gap junctions, emphasizing a potential role for glia-glia and glia-neuron connections in the generation of epileptic seizures.

Published
2019
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