242 results on '"Wakabayashi, Hironao"'
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2. Extending the Spacing between the Shine–Dalgarno Sequence and P-Site Codon Reduces the Rate of mRNA Translocation
3. Author Correction: Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants
4. Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models
5. Cofactor Activity in Factor VIIIa of the Blood Clotting Pathway Is Stabilized by an Interdomain Bond between His281 and Ser524 Formed in Factor VIII
6. Replacing the Factor VIII C1 Domain with a Second C2 Domain Reduces Factor VIII Stability and Affinity for Factor IXa
7. Sequences Flanking Arg336 in Factor VIIIa Modulate Factor Xa-catalyzed Cleavage Rates at this Site and Cofactor Function
8. Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants
9. Increasing Hydrophobicity or Disulfide Bridging at the Factor VIII A1 and C2 Domain Interface Enhances Procofactor Stability
10. The role of P4-P3’ residues flanking Arg336 in facilitating activated protein C-catalyzed cleavage and inactivation of factor VIIIa
11. Effects of Replacement of Factor VIII Amino Acids Asp519 and Glu665 with Val on Plasma Survival and Efficacy In Vivo
12. Factor VIII Lacking the C2 Domain Retains Cofactor Activity in Vitro
13. Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation
14. Generation of enhanced stability factor VIII variants by replacement of charged residues at the A2 domain interface
15. Identification of Residues Contributing to A2 Domain-dependent Structural Stability in Factor VIII and Factor VIIIa
16. Residues Surrounding Arg336 and Arg562 Contribute to the Disparate Rates of Proteolysis of Factor VIIIa Catalyzed by Activated Protein C
17. Mn (super)2+ binding to factor VIII subunits and its effect on cofactor activity
18. Ca (super)2+ binding to both the heavy and light chains of factor VIII is required for cofactor activity
19. Metal ion-independent association of factor VIII subunits and the roles of calcium and copper ions for cofactor activity and inter-subunit affinity
20. Extending the spacing between the Shine-Dalgarno sequence and P-site codon reduces the rate of mRNA translocation
21. Thrombin-catalyzed activation of factor VIII with His substituted for Arg372 at the P1 site
22. Exosite-interactive Regions in the A1 and A2 Domains of Factor VIII Facilitate Thrombin-catalyzed Cleavage of Heavy Chain
23. Differential motility stimulation but not growth stimulation or adhesion of metastatic human colorectal carcinoma cells by target organ-derived liver sinusoidal endothelial cells
24. Cell surface laminin-like substances and laminin-related carbohydrates of rat ascites hepatoma AH7974 and its variants with different lung-colonizing potential
25. Mechanisms of Interactions of Factor X and Factor Xa with the Acidic Region in the Factor VIII A1 Domain
26. Identification of a Factor Xa-interactive Site within Residues 337–372 of the Factor VIII Heavy Chain
27. Residues 110–126 in the A1 Domain of Factor VIII Contain a Ca2+ Binding Site Required for Cofactor Activity
28. Localization of a pH-dependent, A2 subunit-interactive surface within the factor VIIIa A1 subunit
29. Substrate adhesiveness and experimental metastatic potential of rat ascites hepatoma AH7974-derived variant sublines
30. Mechanisms of Factor Xa-catalyzed Cleavage of the Factor VIIIa A1 Subunit Resulting in Cofactor Inactivation
31. Altered Interactions between the A1 and A2 Subunits of Factor VIIIa following Cleavage of A1 Subunit by Factor Xa
32. Cleavage of Factor VIII Heavy Chain Is Required for the Functional Interaction of A2 Subunit with Factor IXa
33. FKS2 and FKS3 Genes of Opportunistic Human Pathogen Candida albicans Influence Echinocandin Susceptibility
34. Correction for Yang et al., “Tolerance to Caspofungin in Candida albicans Is Associated with at Least Three Distinctive Mechanisms That Govern Expression of FKS Genes and Cell Wall Remodeling”
35. The Glu113 Ala mutation within a factor VIII Ca(super 2+)-binding site enhances cofactor interactions in factor xase
36. Correction to: NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins
37. NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins
38. Tolerance to Caspofungin in Candida albicans Is Associated with at Least Three Distinctive Mechanisms That Govern Expression of FKS Genes and Cell Wall Remodeling
39. Chromosome 5 of Human Pathogen Candida albicans Carries Multiple Genes for Negative Control of Caspofungin and Anidulafungin Susceptibility
40. Candida albicans Carriage in Children with Severe Early Childhood Caries (S-ECC) and Maternal Relatedness
41. Combining mutations that modulate inter-subunit interactions and proteolytic inactivation enhance the stability of factor VIIIa
42. Enhanced factor VIIIa stability of A2 domain interface variants results from an increased apparent affinity for the A2 subunit
43. Stabilizing Factor VIIIa By Combining Mutations That Modulate Inter-Subunit Interactions and Proteolytic Inactivation
44. Modification of Interdomain Interfaces within the A3C1C2 Subunit of Factor VIII Affects Its Stability and Activity
45. Molecular orientation of Factor VIIIa on the phospholipid membrane surface determined by fluorescence resonance energy transfer
46. The mild phenotype in severe hemophilia A with Arg1781His mutation is associated with enhanced binding affinity of factor VIII for factor X
47. Contribution of factor VIII light-chain residues 2007–2016 to an activated protein C-interactive site
48. A Coagulation Mechanism for the Mild Bleeding Tendency in a Patient with Severe Hemophilia A Possessing an Arg1781His Mutation.
49. Factor VIII Light Chain Contains a Binding Site for Factor X That Contributes to the Catalytic Efficiency of Factor Xase
50. Membrane-binding properties of the Factor VIII C2 domain
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