Search

The purpose of this study was to evaluate the role of 2-D speckle tracking imaging in assessing left ventricular diastolic function in patients with connective tissue disease (CTD). A total of 98 CTD patients and 32 healthy controls were prospectively recruited. Early (E) and late (A) diastolic velocities of the transmitral flow were measured by pulsed Doppler echocardiography. Peak early diastolic myocardial velocity (E') was calculated on tissue Doppler echocardiography. The longitudinal strain rate (SR) was calculated as the average of three apical views, while circumferential and radial SRs were measured in three short-axis views. Pulmonary arterial hypertension (PAH) was defined as systolic pulmonary arterial pressure (sPAP) >36 mm Hg. Compared with the control group, CTD patients exhibited significant impairment of left ventricular diastolic function, manifested as lower global SR during early diastole (SRe) in the longitudinal deformation and higher E/SRe in both longitudinal and radial deformation. CTD-PAH patients had significantly lower SRe and higher E/SRe values in both the longitudinal and radial deformation compared with the patients with CTD without PAH. Pearson's correlation analysis revealed that sPAP levels correlated positively with E/E', longitudinal E/SRe, circumferential E/SRe and radial SRe, and it correlated negatively with septal E' and radial E/SRe. Receiver operating characteristic curve analysis suggested that E/E', longitudinal E/SRe and radial SRe could be used to predict PAH. The present study indicates that 2-D speckle tracking imaging is a useful method for evaluation of left ventricular diastolic function, and these derived parameters can serve as good predictors of PAH, but it may not be superior to the commonly used E/E' in CTD patients.

At the same condition, utilizing the different of base, the authors constructed two wholly different compounds, 1 and 2. Compounds 1 and 2 are one-dimensional (1D) chainlike, while the coordination mode of dicyandiamide is different in both complexes. In 1, the dicyandiamide is μ 1,5-dca bridged coordination mode; in 2, that is μ 1,3-dca bridged coordination mode. Two new heterobinuclear nickel and sodium polymers [NiN a(L)(dca)] n (1) and [NiNa(L)(dca)] 2n ·(CH3COOCH3) n ·(H2O) n , (2) [where H2L = N,N′-bis(3-ethoxy- salicylidene)ethylenediamine, dca = N(CN)2 –], were synthesized and characterized by elemental analysis and X-ray crystal diffraction. The heterobinuclear complex 1, C22H22N5NaNiO4, crystallizes in the monoclinic system space group P21 /c, with a = 8.0955 (7) A, b = 22.1988 (18) A, c = 12.9314 (11) A; β = 103.4700(10)°; Z = 4; S = 1.01; V = 2260.0(3) A3; D Calcd = 1.476 gcm–3; F(000) = 1040; μ = 0.92 mm–1; R 1 = 0.041; wR 2 = 0.104. The complex 2, C23.50H27N5NaNiO5.50, the crystals belong to...

Background To observe the efficacy of self-help position therapy (SHPT) after holmium laser lithotripsy via flexible ureteroscopy (FURS). Methods From January 2010 to November 2015, 736 nephrolithiasis patients who had received FURS lithotripsy were analyzed retrospectively. In position group, 220 cases accepted SHPT after lithotripsies, and 428 cases as control, coming from another independent inpatient area in the same center. The stone-free status (SFS) between two groups were compared at the 2nd, 4th and 12th week ends by X-ray examinations. Results The preoperative incidence of hydronephrosis (25.9% vs. 18.0%, p = 0.018) or lower calyceal seeper (33.6% vs. 24.3%, p = 0.012) and the proportion of patients with > 2.0 cm stones (33.6% vs. 24.3%, p = 0.003) were all significantly higher in position group than in control group. There were no substantial difference between two groups in age, BMI, gender and medical histories. In postoperative followup, the incidence of hydronephrosis in position group was significantly lower than in control group (9.5% vs. 15.7%, p = 0.032) after removing double-J stents. In position group, the SFS of the 2nd week end (60.9% vs. 47.2%, p = 0.001), the 4th week end (74.1% vs. 62.8%, p = 0.004) and the 12th week end (86.9% vs. 79.4%, p = 0.021) were all significantly higher than those in control group. Conclusions SHPT after holmium laser lithotripsy via FURS may increase postoperative SFS, accelerate stone fragment clearance, and decrease the incidence of hydronephrosis after removal of double-J stents. The therapy does not require professional assistance and is economical, simple, and effective. Electronic supplementary material The online version of this article (10.1186/s12894-018-0348-1) contains supplementary material, which is available to authorized users.

In the title complex, [Ni(C10H7NO4)(H2O)3]·H2O, a mononuclear nickel(II) compound, the NiII atom is six-coordinated in an octa­hedral geometry by the imine N, the phenolate O and a carboxyl O atom from the tridentate Schiff base ligand, and by three O atoms from three coordinated water mol­ecules. In the crystal structure, the mol­ecules are linked through inter­molecular O—H⋯O hydrogen bonds, forming a three-dimensional framework.

In the polymeric title compound, {[Cu(C10H7NO5)(C5H5N)]·H2O}n, the Cu atom adopts square-based pyramidal coordination involving the tridentate N,O,O′-chelated dianionic ligand, a pyridine N atom and an apical, bridging, carboxyl­ate O atom from an adjacent ligand. This results in helical chains propagating along the b axis of the monoclinic unit cell.

In the title controsymmetric dimeric copper(II) compound, [Cu2(C10H7NO4)2(H2O)2], the CuII ion is five-coordinated in a square-pyramidal configuration, with one imine N atom, one phenolate O atom, one carboxylate O atom of the Schiff base and one O atom of a coordinated water mol­ecule defining the basal plane, and the phenolate O atom of another Schiff base occupying the apical position. The CuII atoms are bridged by two phenolic O atoms, with a Cu⋯Cu distance of 3.250 (4) A. In the crystal structure, the mol­ecules are linked through inter­molecular O—H⋯O hydrogen bonds, forming chains running along the b axis.

In the polymeric title compound, [[Cu(C(10)H(7)NO(5))(H(2)O)].H(2)O](n), the Cu atom adopts a square-based pyramidal coordination involving a N,O,O'-tridentate glycine dianionic ligand, a water O atom and an apical bridging carboxylate O atom from an adjacent ligand. The title compound also adopts a carboxylate-bridged chain structure. The molecular chain propagates in a helical fashion along the b axis of the monoclinic unit cell. Neighbouring chains are linked together to form a three-dimensional network via hydrogen-bonding interactions between coordinated and uncoordinated water molecules and O atoms of the bridging carboxylate groups.