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Objective To analyze the correlation of osteoprotegerin, TGF-β 1 and glucose metabolism indicators in type 2 diabetes patients with coronary heart disease. Methods 124 diabetes patients were divided into diabetic and coronary heart disease group (A), diabetic and non- CHD group (group B), there were 51 and 73 cases separately. 40 healthy people were selected as control group (group C). OPG, TGF-β 1, FPG, HbA1c, FINS and HOMA-IR were detected in each group. Results OPG and TGF-β 1 in Group B were significantly higher than that in group C (P < 0.05), OPG and TGF-β 1 in group A were significantly higher than group B, group C (P< 0.05) . FPG, HbA1c, FINS and HOMA-IR in Group B had significant difference with group C (P < 0.05). HbA1c, HOMA-IR in A group were significantly higher than B, C group (P < 0.05), FPG, FINS in A group were significantly higher than C group (P <0.05) .OPG and FPG, HbA1c, FINS and HOMA-IR were significantly positively correlated (P < 0.05), TGF-β 1 and HbA1c, HOMA-IR showed significant positive correlation (P < 0.05) . Conclusion High levels of TGF- β 1 and OPG are important factors leading to cardiovascular complications and are significantly correlated with HbA1c, HOMA-IR. [ABSTRACT FROM AUTHOR]

In this study, tibial shaft fracture has been treated with implants as numerically to investigate the stress behavior and the effect of plate material, position and length under pressure load. Plates of stainless steel, titanium alloy(Ti6Al4V), or CF-PEEK(CF50) were used to fix the tibial shaft comminuted fracture in different location and different working length. The maximum stress, the maximum micromotion of fracture and the stress shielding of cortex bone were analyzed. CF50 is more ideal biomechanical fixation material than traditional metal material for the treatment of tibial shaft comminuted fractures. In the treatment of tibial shaft comminuted fracture, lateral position and with relatively long working length of the plate have the advantages in micromotion, stress and stress shielding rate of the fracture end.

Objective: To investigate the clinical application of fluoro-navigation in the surgery for pelvic fractures., Methods: A fluoro-navigation system was used to guide the placement of screws for the fixation of pelvic and acetabular fractures in 22 patients, 14 males and 8 females, aged 39.4. Totally 41 screws were inserted, 15 in pubic ramus, 13 in acetabulums, and 13 in sacroiliac joints. The images of fluoro-navigation were compared with those of the real X rays during and after surgery., Results: The average time for operation was 22.7 minutes/screw, and the average time of X rays exposure was 20.2 seconds/screw. The mean deviated distance was 2.9 +/- 1.2 mm and the mean deviated angle was (2.2 +/- 0.3) degrees in the post operational verification. The blood loss during the operation was minimal (< 21.7 ml/screw). One screw (2.4%) was deviated out of the fracture during the operation. No complication was recorded after surgery., Conclusion: Fluoro-navigation-assisted operation for the pelvic and acetabular fracture makes the surgery more precise, safer, and time-saving with less X-ray exposure.