44 results on '"ZONGZE YANG"'
Search Results
2. The design and implementation of natural population cohort study Biobank: A multiple-center project cooperation with medical consortia in Southwest China
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Ping Fan, Shu Zhang, Weiya Wang, Zongze Yang, Weiwei Tan, Shujun Li, Chenxing Zhu, Dan Hu, Xinran Zhou, Zixuan Tian, Yaxi Wang, Fang Liu, Wei Huang, and Lei Chen
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natural population cohort study ,medical consortia ,Biobank ,big data ,health management policies ,Public aspects of medicine ,RA1-1270 - Abstract
ObjectiveThe West China Hospital of Sichuan University collaborated with regional medical consortia in Sichuan Province to launch a natural population cohort study (NPCS) to investigate the health status of residents and collect public health data in southwest China.MethodsUp to 80,000 participants will be enrolled by the NPCS from 11 regional medical consortia over five years. Individuals are invited to visit one of 11 participating medical consortia to fill out questionnaires, receive a free health exam, and donate biospecimens upon enrolment. All participating medical facilities adhered to standard operating procedures for collecting and processing biospecimens to ensure uniformity (serum, lithium heparinized plasma, ethylene diamine tetraacetie acid plasma, and buffy coat). The Electronic Data Capture System, Picture Archiving and Communication System, Laboratory Information Management System, Biospecimen Quality Control System, Biobank Information Management System, and will be used to sort and classify clinical indices, imaging data, laboratory parameters, pre-analytical variables, and biospecimen information, respectively. All quality assurance and quality control procedures in the NPCS biobank adhered to the “DAIDS Guidelines for Good Clinical Laboratory Practice Standards”. This project will integrate high-dimensional multi-omics data, laboratory data, clinical data, questionnaire data, and environmental risk factors.ResultsAn estimated 2,240,000 aliquots of the sample will be stored by the end of the study. These samples are linked with comprehensively collected clinical indices, imaging data, and laboratory parameters. Big data analysis can be implemented to create predictive algorithms, explore pathogenesis mechanisms, uncover potential biomarkers, and provide information on public health.ConclusionsNPCS will provide an integrative approach to research risk factors and pathogenesis of major chronic or endemic diseases in Sichuan Province and provide key scientific evidence to support the formulation of health management policies in China.
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- 2022
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3. A Galerkin FEM for Riesz space-fractional CNLS
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Xiaogang Zhu, Yufeng Nie, Zhanbin Yuan, Jungang Wang, and Zongze Yang
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Space-fractional CNLS ,FEM ,Convergent analysis ,Mathematics ,QA1-939 - Abstract
Abstract In quantum physics, fractional Schrödinger equation is of particular interest in the research of particles on stochastic fields modeled by the Lévy processes, which was derived by extending the Feynman path integral over the Brownian paths to a path integral over the trajectories of Lévy fights. In this work, a fully discrete finite element method (FEM) is developed for the Riesz space-fractional coupled nonlinear Schrödinger equations (CNLS), conjectured with a linearized Crank–Nicolson discretization. The error estimate and mass conservative property are discussed. It is showed that the proposed method is decoupled and convergent with optimal orders in L2 $L^{2}$-sense. Numerical examples are performed to support our theoretical results.
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- 2019
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4. An extracted tetraploid wheat harbouring the BBAA component of common wheat shows anomalous shikimate and sucrose metabolism
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Ruili Lv, Lei Han, Binbin Xiao, Chaoxia Xiao, Zongze Yang, Hao Wang, Huan Wang, Bao Liu, and Chunwu Yang
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Polyploidy ,Extracted tetraploid wheat ,Subgenome ,Metabolomics and proteomics ,Gene expression ,Phenotype abnormality ,Botany ,QK1-989 - Abstract
Abstract Background The BBAA subgenomes of hexaploid common wheat are structurally intact, which makes it possible to extract the BBAA subgenomes to constitute a novel plant type, namely, extracted tetraploid wheat (ETW). ETW displays multiple abnormal phenotypes such as massively reduced biomass and abnormal spike development, compared to extant tetraploid wheat with a BBAA genome. The genetic, biochemical and physiological basis underlying the phenotypic abnormality of ETW remains unknown. Results To explore the biochemical basis of these phenotypic abnormalities, we analysed the metabolomic and proteomic profiles and quantified 46 physiological traits of ETW in comparison with its common wheat donor (genome BBAADD), and a durum tetraploid wheat cultivar (genome BBAA). Among these three types of wheat, ETW showed a saliently different pattern of nutrient accumulation and seed quality, markedly lower concentrations of many metabolites involved in carbohydrate metabolism, and higher concentrations of many metabolites related to amino acids. Among the metabolites, changes in shikimate and sucrose were the most conspicuous. Higher levels of shikimate and lower levels of sucrose influence many metabolic processes including carbohydrate and amino acid metabolism, which may contribute to the phenotypic abnormalities. Gene expression assay showed downregulation of a shikimate degradation enzyme (5-enolpyruvylshikimate-3-phosphate synthase) coding gene and upregulation of several genes coding for the sucrose hydrolysis enzyme, which could explain the higher levels of shikimate and lower levels of sucrose, respectively. Conclusions Our results suggest that significant and irreversible biochemical changes have occurred in the BBAA subgenomes of common wheat during the course of its co-evolution with the DD subgenome at the hexaploid level.
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- 2019
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5. A newly formed hexaploid wheat exhibits immediate higher tolerance to nitrogen-deficiency than its parental lines
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Chunwu Yang, Zongze Yang, Long Zhao, Fasheng Sun, and Bao Liu
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Wheat ,Nitrogen uptake ,Nitrate transporter ,Allopolyploidy ,Gene expression ,Adaptation ,Botany ,QK1-989 - Abstract
Abstract Background It is known that hexaploid common wheat (Triticum aestivum L.) has stronger adaptability to many stressful environments than its tetraploid wheat progenitor. However, the physiological basis and evolutionary course to acquire these enhanced adaptabilities by common wheat remain understudied. Here, we aimed to investigate whether and by what means tolerance to low-nitrogen manifested by common wheat may emerge immediately following allohexaploidization. Results We compared traits related to nitrogen (N) metabolism in a synthetic allohexaploid wheat (neo-6×, BBAADD) mimicking natural common wheat, together with its tetraploid (BBAA, 4×) and diploid (DD, 2×) parents. We found that, under low nitrogen condition, neo-6× maintained largely normal photosynthesis, higher shoot N accumulation, and better N assimilation than its 4× and 2× parents. We showed that multiple mechanisms underlie the enhanced tolerance to N-deficiency in neo-6×. At morphological level, neo-6× has higher root/shoot ratio of biomass than its parents, which might be an adaptive growth strategy as more roots feed less shoots with N, thereby enabling higher N accumulation in the shoots. At electrophysiological level, H+ efflux in neo-6× is higher than in its 4× parent. A stronger H+ efflux may enable a higher N uptake capacity of neo-6×. At gene expression level, neo-6× displayed markedly higher expression levels of critical genes involved in N uptake than both of its 4× and 2× parents. Conclusions This study documents that allohexaploid wheat can attain immediate higher tolerance to N-deficiency compared with both of its 4× and 2× parents, and which was accomplished via multiple mechanisms.
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- 2018
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6. An exponential B-spline collocation method for the fractional sub-diffusion equation
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Xiaogang Zhu, Yufeng Nie, Zhanbin Yuan, Jungang Wang, and Zongze Yang
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fractional sub-diffusion equation ,exponential B-spline collocation method ,unique solvability ,unconditional stability ,Mathematics ,QA1-939 - Abstract
Abstract In this article, we propose an exponential B-spline approach to obtain approximate solutions for the fractional sub-diffusion equation of Caputo type. The presented method is established via a uniform nodal collocation strategy by using an exponential B-spline based interpolation in conjunction with an effective finite difference scheme in time. The unique solvability is rigorously proved. The unconditional stability is well illustrated via a procedure closely resembling the classic von Neumann technique. A series of numerical examples are carried out, and by contrast to other algorithms available in the open literature, numerical results confirm the validity and superiority of our method.
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- 2017
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7. Finite element method for time-space-fractional Schrodinger equation
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Xiaogang Zhu, Zhanbin Yuan, Jungang Wang, Yufeng Nie, and Zongze Yang
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Time-space-fractional NLS ,finite element method ,convergence ,Mathematics ,QA1-939 - Abstract
In this article, we develop a fully discrete finite element method for the nonlinear Schrodinger equation (NLS) with time- and space-fractional derivatives. The time-fractional derivative is described in Caputo's sense and the space-fractional derivative in Riesz's sense. Its stability is well derived; the convergent estimate is discussed by an orthogonal operator. We also extend the method to the two-dimensional time-space-fractional NLS and to avoid the iterative solvers at each time step, a linearized scheme is further conducted. Several numerical examples are implemented finally, which confirm the theoretical results as well as illustrate the accuracy of our methods.
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- 2017
8. MircoRNA-145 promotes activation of hepatic stellate cells via targeting krüppel-like factor 4
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Ruoting Men, Maoyao Wen, Mingyue Zhao, Xuelian Dan, Zongze Yang, Wenchao Wu, Maggie Haitian Wang, Xiaojing Liu, and Li Yang
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Medicine ,Science - Abstract
Abstract Krüppel-like Factor 4 (KLF4), a target gene of miR-145, can negatively regulate lung fibrosis. However, the potential role of KLF4 and miR-145 in hepatic stellate cells (HSCs) activation or in hepatic fibrosis keeps unclear. This study aims to characterize miR-145 and KLF4 in activated HSCs and liver cirrhotic, and the underlying molecular basis. miR-145 was significantly up-regulated, while KLF4 was dramatically down-regulated during the activation of rat primary HSCs and TGF-βtreated HSCs. Furthermore, miR-145 mimics induced and inhibition of miR-145 reduced α-SMA and COL-I expression in primary HSCs. Additionally, the mRNA and protein levels of KLF4 in the liver of cirrhotic patients and rats were significantly down-regulated. α-SMA and COL-I were increased after inhibition of KLF4 by specific shRNA in primary HSCs. Forced KLF4 expression led to a reduction of α-SMA and COL-I expression in HSCs. miR-145 promotes HSC activation and liver fibrosis by targeting KLF4.
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- 2017
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9. Transcriptomic Profiling and Physiological Responses of Halophyte Kochia sieversiana Provide Insights into Salt Tolerance
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Long Zhao, Zongze Yang, Qiaobing Guo, Shun Mao, Shaoqiang Li, Fasheng Sun, Huan Wang, and Chunwu Yang
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halophyte ,RNAseq ,Na+ ,water balance ,root ,Plant culture ,SB1-1110 - Abstract
Halophytes are remarkable plants that can tolerate extremely high-salinity conditions, and have different salinity tolerance mechanisms from those of glycophytic plants. In this work, we investigated the mechanisms of salinity tolerance of an extreme halophyte, Kochia sieversiana (Pall.) C. A. M, using RNA sequencing and physiological tests. The results showed that moderate salinity stimulated the growth and water uptake of K. sieversiana and, even under 480-mM salinity condition, K. sieversiana maintained an extremely high water content. This high water content may be a specific adaptive strategy of K. sieversiana to high salinity. The physiological analysis indicated that increasing succulence and great accumulations of sodium, alanine, sucrose, and maltose may be favorable to the water uptake and osmotic regulation of K. sieversiana under high-salinity stress. Transcriptome data indicated that some aquaporin genes and potassium (K+) transporter genes may be important for water uptake and ion balance, respectively, while different members of those gene families were employed under low- and high-salinity stresses. In addition, several aquaporin genes were up-regulated in low- but not high-salinity stressed roots. The highly expressed aquaporin genes may allow low-salinity stressed K. sieversiana plants to uptake more water than control plants. The leaf K+/root K+ ratio was enhanced under low- but not high-salinity stress, which suggested that low salinity might promote K+ transport from the roots to the shoots. Hence, we speculated that low salinity might allow K. sieversiana to uptake more water and transport more K+ from roots to shoots, increasing the growth rate of K. sieversiana.
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- 2017
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10. Optimal \(\boldsymbol{{L^2}}\) Error Estimates of Unconditionally Stable Finite Element Schemes for the Cahn-Hilliard-Navier-Stokes System.
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Wentao Cai 0007, Weiwei Sun 0002, Jilu Wang, and Zongze Yang
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- 2023
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11. An optimized CIP-FEM to reduce the pollution errors for the Helmholtz equation on a general unstructured mesh.
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Buyang Li, Yonglin Li, and Zongze Yang
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- 2024
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12. High-order splitting finite element methods for the subdiffusion equation with limited smoothing property.
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Buyang Li, Zongze Yang, and Zhi Zhou 0002
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- 2023
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13. A quadrature scheme for steady-state diffusion equations involving fractional power of regularly accretive operator.
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Beiping Duan and Zongze Yang
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- 2023
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14. Using Gauss-Jacobi quadrature rule to improve the accuracy of FEM for spatial fractional problems.
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Zongze Yang, Jungang Wang, Zhanbin Yuan, and Yufeng Nie 0001
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- 2022
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15. A mass conservative, well balanced, tangency preserving and energy decaying method for the shallow water equations on a sphere.
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Max D. Gunzburger, Buyang Li, Jilu Wang, and Zongze Yang
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- 2022
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16. An energy diminishing arbitrary Lagrangian-Eulerian finite element method for two-phase Navier-Stokes flow.
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Beiping Duan, Buyang Li, and Zongze Yang
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- 2022
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17. A Convergent Post-processed Discontinuous Galerkin Method for Incompressible Flow with Variable Density.
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Buyang Li, Weifeng Qiu, and Zongze Yang
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- 2022
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18. Finite element methods for fractional PDEs in three dimensions.
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Zongze Yang, Yufeng Nie 0001, Zhanbin Yuan, and Jungang Wang
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- 2020
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19. Effective numerical treatment of sub-diffusion equation with non-smooth solution.
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Zongze Yang, Jungang Wang, Yan Li, and Yufeng Nie 0001
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- 2018
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20. Finite element method for nonlinear Riesz space fractional diffusion equations on irregular domains.
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Zongze Yang, Zhanbin Yuan, Yufeng Nie 0001, Jungang Wang, Xiaogang Zhu 0002, and Fawang Liu
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- 2017
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21. Optimal convergence of arbitrary Lagrangian–Eulerian iso-parametric finite element methods for parabolic equations in an evolving domain
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Buyang Li, Yinhua Xia, and Zongze Yang
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Computational Mathematics ,Applied Mathematics ,General Mathematics - Abstract
An optimal-order error estimate is presented for the arbitrary Lagrangian–Eulerian (ALE) finite element method for a parabolic equation in an evolving domain, using high-order iso-parametric finite elements with flat simplices in the interior of the domain. The mesh velocity can be a linear approximation of a given bulk velocity field or a numerical solution of the Laplace equation with specified boundary value matching the velocity of the boundary. The optimal order of convergence is obtained by comparing the numerical solution with the ALE-Ritz projection of the exact solution, and by establishing an optimal-order estimate for the material derivative of the ALE-Ritz projection error.
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- 2022
22. An unstructured mesh finite difference/finite element method for the three-dimensional time-space fractional Bloch-Torrey equations on irregular domains.
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Zongze Yang, Fawang Liu, Yufeng Nie 0001, and Ian W. Turner
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- 2020
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23. Using Gauss-Jacobi quadrature rule to improve the accuracy of FEM for spatial fractional problems
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Zongze Yang, Yufeng Nie, Zhanbin Yuan, and Jungang Wang
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symbols.namesake ,Singularity ,Applied Mathematics ,Numerical analysis ,Gaussian ,symbols ,Gauss–Jacobi quadrature ,Applied mathematics ,Gaussian quadrature ,Finite element method ,Fractional calculus ,Mathematics ,Stiffness matrix - Abstract
Though the finite element method has been widely used in solving fractional differential equations, the effects of the Gaussian quadrature rule on the numerical results have rarely been considered. Since the fractional derivatives of the basis functions are not polynomials with integer power and always have weak singularities on some elements, the Gaussian quadrature rule (Gauss-Legendre quadrature rule) may not be suitable in assembling the fractional stiffness matrix. By splitting the integrand of the inner products into a weak singularity part and a smooth part and utilizing the Gauss-Jacobi quadrature rule for the weak singularity part, we present a modified algorithm to assemble the fractional stiffness matrix. The numerical results, conducted on 1D and 2D domains, show that our method can significantly improve the accuracy of the stiffness matrix as well as the accuracy of the numerical solution with much fewer Gaussian points.
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- 2021
24. OPTIMAL L² ERROR ESTIMATES OF UNCONDITIONALLY STABLE FINITE ELEMENT SCHEMES FOR THE CAHN--HILLIARD--NAVIER--STOKES SYSTEM.
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WENTAO CAI, WEIWEI SUN, JILU WANG, and ZONGZE YANG
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FINITE element method ,INTERPOLATION - Abstract
The paper is concerned with the analysis of a popular convex-splitting finite element method (FEM) for the Cahn--Hilliard--Navier--Stokes system, which has been widely used in practice. Since the method is based on a combined approximation to multiple variables involved in the system, the approximation to one of the variables may seriously affect the accuracy for others. Optimal-order error analysis for such combined approximations is challenging. The previous works failed to present optimal error analysis in L²-norm due to the weakness of the traditional approach. Here we first present an optimal error estimate in L²-norm for the convex-splitting FEMs. We also show that optimal error estimates in the traditional (interpolation) sense may not always hold for all components in the coupled system due to the nature of the pollution/influence from lower-order approximations. Our analysis is based on two newly introduced elliptic quasi-projections and the superconvergence of negative norm estimates for the corresponding projection errors. Numerical examples are also presented to illustrate our theoretical results. More important is that our approach can be extended to many other FEMs and other strongly coupled phase field models to obtain optimal error estimates. [ABSTRACT FROM AUTHOR]
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- 2023
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25. An exponential B-spline collocation method for the fractional sub-diffusion equation
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Yufeng Nie, Zhanbin Yuan, Jungang Wang, Zongze Yang, and Xiaogang Zhu
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Algebra and Number Theory ,Collocation ,Partial differential equation ,Diffusion equation ,Applied Mathematics ,B-spline ,exponential B-spline collocation method ,lcsh:Mathematics ,010103 numerical & computational mathematics ,fractional sub-diffusion equation ,lcsh:QA1-939 ,01 natural sciences ,Exponential function ,010101 applied mathematics ,Collocation method ,Ordinary differential equation ,Applied mathematics ,unconditional stability ,0101 mathematics ,unique solvability ,Analysis ,Mathematics ,Interpolation - Abstract
In this article, we propose an exponential B-spline approach to obtain approximate solutions for the fractional sub-diffusion equation of Caputo type. The presented method is established via a uniform nodal collocation strategy by using an exponential B-spline based interpolation in conjunction with an effective finite difference scheme in time. The unique solvability is rigorously proved. The unconditional stability is well illustrated via a procedure closely resembling the classic von Neumann technique. A series of numerical examples are carried out, and by contrast to other algorithms available in the open literature, numerical results confirm the validity and superiority of our method.
- Published
- 2017
26. Drought Enhances Nitrogen Uptake and Assimilation in Maize Roots
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Zongze Yang, Yong Wang, Zhian Zhang, Huan Wang, Zhang He, Bao Liu, Li Jiang, Chunwu Yang, Guan Wang, Siyu Chen, and Yanan Yu
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0106 biological sciences ,0301 basic medicine ,Drought stress ,fungi ,Drought tolerance ,food and beverages ,chemistry.chemical_element ,Assimilation (biology) ,Metabolism ,Biology ,Photosynthesis ,01 natural sciences ,Nitrogen ,03 medical and health sciences ,chemistry.chemical_compound ,030104 developmental biology ,chemistry ,Agronomy ,Ammonium ,Agronomy and Crop Science ,Nitrogen cycle ,010606 plant biology & botany - Abstract
Nitrogen metabolism has important roles in plant drought tolerance, and higher N uptake can enhance plant drought tolerance. The aim of this study was to investigate the role of N metabolism regulation in maize drought tolerance. We measured the expression of genes known to be involved in N uptake and assimilation, together with various photosynthetic parameters, and nutrient content, in different tissues from maize plants exposed to water deficit conditions. Different tissues displayed significant differences in their regulation of N metabolism during the adaptation of maize plants to drought stress. The impact of drought on ammonium (NH₄⁺) assimilation was much greater in old and mature leaves than in younger leaves. Correspondingly, drought had a smaller effect on photosynthesis in young leaves than in old and mature leaves, suggesting that the disruption of NH₄⁺ assimilation in the latter may be attributable to a greater reduction in photosynthesis. In roots, we found that drought stress dramatically enhanced the expression levels of nearly all genes involved in N uptake and assimilation, including AMT1;3, AMT1;1b, NRT1;2 and NRT2;5, NR, GS2, and GS1;2. We suggest that increasing the expression of AMT1;1b, AMT1;3, NRT1;2, and NRT2;5 in maize roots under drought condition will increase N uptake and promote rapid accumulation of amino acids. The data revealed that AMT1;1b, AMT1;3, NRT1;2, and NRT2;5 may play important roles in drought tolerance of maize.
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- 2017
27. A Galerkin FEM for Riesz space-fractional CNLS
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Zongze Yang, Zhanbin Yuan, Yufeng Nie, Jungang Wang, and Xiaogang Zhu
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FEM ,Algebra and Number Theory ,Partial differential equation ,Discretization ,lcsh:Mathematics ,Applied Mathematics ,010102 general mathematics ,Mathematical analysis ,Riesz space ,lcsh:QA1-939 ,01 natural sciences ,Finite element method ,Schrödinger equation ,Convergent analysis ,010101 applied mathematics ,symbols.namesake ,Nonlinear system ,Ordinary differential equation ,Path integral formulation ,symbols ,Space-fractional CNLS ,0101 mathematics ,Analysis ,Mathematics - Abstract
In quantum physics, fractional Schrodinger equation is of particular interest in the research of particles on stochastic fields modeled by the Levy processes, which was derived by extending the Feynman path integral over the Brownian paths to a path integral over the trajectories of Levy fights. In this work, a fully discrete finite element method (FEM) is developed for the Riesz space-fractional coupled nonlinear Schrodinger equations (CNLS), conjectured with a linearized Crank–Nicolson discretization. The error estimate and mass conservative property are discussed. It is showed that the proposed method is decoupled and convergent with optimal orders in $L^{2}$ -sense. Numerical examples are performed to support our theoretical results.
- Published
- 2019
28. An extracted tetraploid wheat harbouring the BBAA component of common wheat shows anomalous shikimate and sucrose metabolism
- Author
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Bao Liu, Zongze Yang, Binbin Xiao, Lei Han, Huan Wang, Hao Wang, Ruili Lv, Chunwu Yang, and Chaoxia Xiao
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0106 biological sciences ,0301 basic medicine ,Sucrose ,Shikimic Acid ,Plant Science ,Carbohydrate metabolism ,Biology ,01 natural sciences ,Genome ,Polyploidy ,03 medical and health sciences ,chemistry.chemical_compound ,Metabolomics ,Gene Expression Regulation, Plant ,lcsh:Botany ,Gene expression ,Common wheat ,Subgenome ,Gene ,Triticum ,Plant Proteins ,Extracted tetraploid wheat ,food and beverages ,Metabolomics and proteomics ,Phenotype ,Biological Evolution ,lcsh:QK1-989 ,Tetraploidy ,030104 developmental biology ,chemistry ,Biochemistry ,Metabolome ,Phenotype abnormality ,Genome, Plant ,010606 plant biology & botany ,Research Article - Abstract
Background The BBAA subgenomes of hexaploid common wheat are structurally intact, which makes it possible to extract the BBAA subgenomes to constitute a novel plant type, namely, extracted tetraploid wheat (ETW). ETW displays multiple abnormal phenotypes such as massively reduced biomass and abnormal spike development, compared to extant tetraploid wheat with a BBAA genome. The genetic, biochemical and physiological basis underlying the phenotypic abnormality of ETW remains unknown. Results To explore the biochemical basis of these phenotypic abnormalities, we analysed the metabolomic and proteomic profiles and quantified 46 physiological traits of ETW in comparison with its common wheat donor (genome BBAADD), and a durum tetraploid wheat cultivar (genome BBAA). Among these three types of wheat, ETW showed a saliently different pattern of nutrient accumulation and seed quality, markedly lower concentrations of many metabolites involved in carbohydrate metabolism, and higher concentrations of many metabolites related to amino acids. Among the metabolites, changes in shikimate and sucrose were the most conspicuous. Higher levels of shikimate and lower levels of sucrose influence many metabolic processes including carbohydrate and amino acid metabolism, which may contribute to the phenotypic abnormalities. Gene expression assay showed downregulation of a shikimate degradation enzyme (5-enolpyruvylshikimate-3-phosphate synthase) coding gene and upregulation of several genes coding for the sucrose hydrolysis enzyme, which could explain the higher levels of shikimate and lower levels of sucrose, respectively. Conclusions Our results suggest that significant and irreversible biochemical changes have occurred in the BBAA subgenomes of common wheat during the course of its co-evolution with the DD subgenome at the hexaploid level. Electronic supplementary material The online version of this article (10.1186/s12870-019-1796-9) contains supplementary material, which is available to authorized users.
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- 2019
29. Additional file 2: of An extracted tetraploid wheat harbouring the BBAA component of common wheat shows anomalous shikimate and sucrose metabolism
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Ruili Lv, Han, Lei, Binbin Xiao, Chaoxia Xiao, Zongze Yang, Wang, Hao, Wang, Huan, Liu, Bao, and Chunwu Yang
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fungi ,food and beverages - Abstract
Figure S2. Frequency distribution of fold changes in protein abundance between extracted tetraploid wheat (ETW) and an extant tetraploid wheat line (AL, genome BBAA) and between ETW and a resynthesized allohexaploid wheat (XX329, genome BBAADD) obtained by crossing ETW (maternal parent) and TQ18 (paternal parent). (PDF 298 kb)
- Published
- 2019
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30. Finite Element Methods for Fractional PDEs in Three Dimensions
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Yufeng Nie, Zhanbin Yuan, Zongze Yang, and Jungang Wang
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Generalization ,Applied Mathematics ,Gaussian ,26A33 (Primary), 35R11, 65M60 (Secondary) ,Regular polygon ,Basis function ,Numerical Analysis (math.NA) ,Finite element method ,Fractional calculus ,symbols.namesake ,Matrix (mathematics) ,Path (graph theory) ,FOS: Mathematics ,symbols ,Applied mathematics ,Mathematics - Numerical Analysis ,Mathematics - Abstract
This paper is a generalization of the previous work (Yang et.al, J. Comput. Phys. 330 (2017), 863-883) to the 3-D irregular convex domains. The analytical calculation formula of fractional derivatives of finite element basis functions are given and a path searching method is developed to find the integration paths corresponding to the Gaussian points. Moreover, a template matrix is introduced to speed up the procedures. Numerical experiments on a steady problem are presented verifying the efficiency of proposed techniques., 7 pages, 3 figures
- Published
- 2018
31. The Value of Circulating Nogo-B for Evaluating Hepatic Functional Reserve in Patients with Cirrhosis
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Xiaojing Liu, Ruoting Men, Wenchao Wu, Li Yang, Xuelian Dan, Maoyao Wen, and Zongze Yang
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Adult ,Liver Cirrhosis ,Male ,medicine.medical_specialty ,Pathology ,Cirrhosis ,Article Subject ,Nogo Proteins ,Clinical Biochemistry ,Inflammation ,Gastroenterology ,Fibrosis ,Internal medicine ,mental disorders ,Genetics ,Humans ,Medicine ,Molecular Biology ,Aged ,Aged, 80 and over ,lcsh:R5-920 ,medicine.diagnostic_test ,business.industry ,Biochemistry (medical) ,Case-control study ,General Medicine ,Middle Aged ,medicine.disease ,Liver ,Case-Control Studies ,Portal hypertension ,Immunohistochemistry ,Female ,Liver function ,medicine.symptom ,lcsh:Medicine (General) ,business ,Liver function tests ,Biomarkers ,Myelin Proteins ,psychological phenomena and processes ,Research Article - Abstract
Objective. To examine Nogo-B in liver tissues and plasma of patients with liver cirrhosis and associate them with various clinical parameters.Materials and Methods. Nogo-B protein expression was examined by immunohistochemistry in 24 human fibrotic/cirrhotic liver specimens and 10 healthy controls. We determined plasma Nogo-B levels by enzyme-linked immunosorbent assay in 301 patients with liver cirrhosis and 153 healthy controls, and then analyzed various clinical parameters.Results. Nogo-B was mainly expressed in nonparenchymal cells in the liver and was marked increased in liver with significant fibrosis/cirrhosis compared to controls. Moreover, Metavir F4 showed a higher level of expression than F2. Plasma Nogo-B levels were significantly higher in cirrhotic patients than in healthy controls and were the highest in Child-Pugh class C patients. Plasma Nogo-B levels were positively correlated with Child-Pugh scores. However, there was no relationship between plasma Nogo-B levels and etiology of liver diseases, ALT, AST, platelet counts, and the severity of esophagogastric varices.Conclusions. Nogo-B is mainly expressed in hepatic nonparenchymal cells and is present in plasma. Abnormally high plasma levels of Nogo-B are associated with hepatic cirrhosis and Child-Pugh score, but not correlated with the grade of liver inflammation or portal hypertension. Plasma Nogo-B may be a novel surrogate marker to reflect liver function reserve.
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- 2015
32. A newly formed hexaploid wheat exhibits immediate higher tolerance to nitrogen-deficiency than its parental lines
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Bao Liu, Chunwu Yang, Fasheng Sun, Zongze Yang, and Long Zhao
- Subjects
0106 biological sciences ,0301 basic medicine ,Nitrogen ,Plant Science ,Biology ,Photosynthesis ,Genes, Plant ,01 natural sciences ,Polyploidy ,03 medical and health sciences ,Nitrate transporter ,Gene Expression Regulation, Plant ,lcsh:Botany ,Gene expression ,Common wheat ,Adaptation ,Gene ,Triticum ,Nitrogen deficiency ,food and beverages ,Allopolyploidy ,Adaptation, Physiological ,Diploidy ,lcsh:QK1-989 ,Horticulture ,030104 developmental biology ,Shoot ,Wheat ,Ploidy ,Nitrogen uptake ,010606 plant biology & botany - Abstract
Background It is known that hexaploid common wheat (Triticum aestivum L.) has stronger adaptability to many stressful environments than its tetraploid wheat progenitor. However, the physiological basis and evolutionary course to acquire these enhanced adaptabilities by common wheat remain understudied. Here, we aimed to investigate whether and by what means tolerance to low-nitrogen manifested by common wheat may emerge immediately following allohexaploidization. Results We compared traits related to nitrogen (N) metabolism in a synthetic allohexaploid wheat (neo-6×, BBAADD) mimicking natural common wheat, together with its tetraploid (BBAA, 4×) and diploid (DD, 2×) parents. We found that, under low nitrogen condition, neo-6× maintained largely normal photosynthesis, higher shoot N accumulation, and better N assimilation than its 4× and 2× parents. We showed that multiple mechanisms underlie the enhanced tolerance to N-deficiency in neo-6×. At morphological level, neo-6× has higher root/shoot ratio of biomass than its parents, which might be an adaptive growth strategy as more roots feed less shoots with N, thereby enabling higher N accumulation in the shoots. At electrophysiological level, H+ efflux in neo-6× is higher than in its 4× parent. A stronger H+ efflux may enable a higher N uptake capacity of neo-6×. At gene expression level, neo-6× displayed markedly higher expression levels of critical genes involved in N uptake than both of its 4× and 2× parents. Conclusions This study documents that allohexaploid wheat can attain immediate higher tolerance to N-deficiency compared with both of its 4× and 2× parents, and which was accomplished via multiple mechanisms.
- Published
- 2017
33. MircoRNA-145 promotes activation of hepatic stellate cells via targeting krüppel-like factor 4
- Author
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Maggie Haitian Wang, Wenchao Wu, Li Yang, Xuelian Dan, Ruoting Men, Xiaojing Liu, Zongze Yang, Mingyue Zhao, and Maoyao Wen
- Subjects
Liver Cirrhosis ,Male ,0301 basic medicine ,Kruppel-Like Transcription Factors ,Down-Regulation ,Article ,Rats, Sprague-Dawley ,Small hairpin RNA ,Kruppel-Like Factor 4 ,Mice ,03 medical and health sciences ,stomatognathic system ,Downregulation and upregulation ,Transforming Growth Factor beta ,microRNA ,Hepatic Stellate Cells ,Animals ,Humans ,Messenger RNA ,Multidisciplinary ,biology ,Chemistry ,fungi ,Transforming growth factor beta ,Up-Regulation ,Cell biology ,MicroRNAs ,030104 developmental biology ,KLF4 ,Gene Knockdown Techniques ,embryonic structures ,Hepatic stellate cell ,biology.protein ,sense organs ,biological phenomena, cell phenomena, and immunity ,Hepatic fibrosis - Abstract
Krüppel-like Factor 4 (KLF4), a target gene of miR-145, can negatively regulate lung fibrosis. However, the potential role of KLF4 and miR-145 in hepatic stellate cells (HSCs) activation or in hepatic fibrosis keeps unclear. This study aims to characterize miR-145 and KLF4 in activated HSCs and liver cirrhotic, and the underlying molecular basis. miR-145 was significantly up-regulated, while KLF4 was dramatically down-regulated during the activation of rat primary HSCs and TGF-βtreated HSCs. Furthermore, miR-145 mimics induced and inhibition of miR-145 reduced α-SMA and COL-I expression in primary HSCs. Additionally, the mRNA and protein levels of KLF4 in the liver of cirrhotic patients and rats were significantly down-regulated. α-SMA and COL-I were increased after inhibition of KLF4 by specific shRNA in primary HSCs. Forced KLF4 expression led to a reduction of α-SMA and COL-I expression in HSCs. miR-145 promotes HSC activation and liver fibrosis by targeting KLF4.
- Published
- 2017
- Full Text
- View/download PDF
34. Evolution of physiological responses to salt stress in hexaploid wheat
- Author
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Sachin Rustgi, Huakun Zhang, Shanshan Wen, Chunyu Zhang, Bao Liu, Zongze Yang, Long Zhao, Diter von Wettstein, Huan Wang, and Chunwu Yang
- Subjects
Salinity ,Nitrogen ,Chromosomes, Plant ,Evolution, Molecular ,Polyploidy ,Osmotic Pressure ,Botany ,Gene expression ,Aegilops tauschii ,Expressivity (genetics) ,Photosynthesis ,Gene ,Triticum ,Genetics ,Multidisciplinary ,biology ,Sodium ,food and beverages ,Xylem ,Salt Tolerance ,Biological Sciences ,biology.organism_classification ,Diploidy ,Tetraploidy ,Germination ,Genetic Fitness ,Ploidy ,Genome, Plant - Abstract
Hexaploid bread wheat (Triticum aestivum L., genome BBAADD) is generally more salt tolerant than its tetraploid wheat progenitor (Triticum turgidum L.). However, little is known about the physiological basis of this trait or about the relative contributions of allohexaploidization and subsequent evolutionary genetic changes on the trait development. Here, we compared the salt tolerance of a synthetic allohexaploid wheat (neo-6x) with its tetraploid (T. turgidum; BBAA) and diploid (Aegilops tauschii; DD) parents, as well as a natural hexaploid bread wheat (nat-6x). We studied 92 morphophysiological traits and analyzed homeologous gene expression of a major salt-tolerance gene High-Affinity K(+) Transporter 1;5 (HKT1;5). We observed that under salt stress, neo-6x exhibited higher fitness than both of its parental genotypes due to inheritance of favorable traits like higher germination rate from the 4x parent and the stronger root Na(+) retention capacity from the 2x parent. Moreover, expression of the D-subgenome HKT1;5 homeolog, which is responsible for Na(+) removal from the xylem vessels, showed an immediate transcriptional reprogramming following allohexaploidization, i.e., from constitutive high basal expression in Ae. tauschii (2x) to salt-induced expression in neo-6x. This phenomenon was also witnessed in the nat-6x. An integrated analysis of 92 traits showed that, under salt-stress conditions, neo-6x resembled more closely the 2x than the 4x parent, suggesting that the salt stress induces enhanced expressivity of the D-subgenome homeologs in the synthetic hexaploid wheat. Collectively, the results suggest that condition-dependent functionalization of the subgenomes might have contributed to the wide-ranging adaptability of natural hexaploid wheat.
- Published
- 2014
35. Effective numerical treatment of sub-diffusion equation with non-smooth solution
- Author
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Zongze Yang, Yufeng Nie, Jungang Wang, and Yan Li
- Subjects
Primary 34A08, Secondary 26A33, 45D05, 65L12 ,Current (mathematics) ,Diffusion equation ,Anomalous diffusion ,Applied Mathematics ,Operator (physics) ,Compact finite difference ,010103 numerical & computational mathematics ,Numerical Analysis (math.NA) ,01 natural sciences ,Computer Science Applications ,010101 applied mathematics ,Computational Theory and Mathematics ,Rate of convergence ,FOS: Mathematics ,Applied mathematics ,Nyström method ,Mathematics - Numerical Analysis ,0101 mathematics ,Spectral method ,Mathematics - Abstract
In this paper we investigate a sub-diffusion equation for simulating the anomalous diffusion phenomenon in real physical environment. Based on an equivalent transformation of the original sub-diffusion equation followed by the use of a smooth operator, we devise a high-order numerical scheme by combining the Nystrom method in temporal direction with the compact finite difference method and the spectral method in spatial direction. The distinct advantage of this approach in comparison with most current methods is its high convergence rate even though the solution of the anomalous sub-diffusion equation usually has lower regularity on the starting point. The effectiveness and efficiency of our proposed method are verified by several numerical experiments., 15 pages, 6 figures
- Published
- 2016
36. Finite element method for nonlinear Riesz space fractional diffusion equations on irregular domains
- Author
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Zhanbin Yuan, Fawang Liu, Xiaogang Zhu, Yufeng Nie, Zongze Yang, and Jungang Wang
- Subjects
Numerical Analysis ,Physics and Astronomy (miscellaneous) ,Applied Mathematics ,Mathematical analysis ,26A33 (Primary), 35R11, 65M60 (Secondary) ,Numerical Analysis (math.NA) ,010103 numerical & computational mathematics ,Riesz space ,Space (mathematics) ,01 natural sciences ,Domain (mathematical analysis) ,Finite element method ,Computer Science Applications ,Fractional calculus ,010101 applied mathematics ,Computational Mathematics ,Nonlinear system ,Modeling and Simulation ,FOS: Mathematics ,Mathematics - Numerical Analysis ,0101 mathematics ,Extended finite element method ,Stiffness matrix ,Mathematics - Abstract
In this paper, we consider two-dimensional Riesz space fractional diffusion equations with nonlinear source term on convex domains. Applying Galerkin finite element method in space and backward difference method in time, we present a fully discrete scheme to solve Riesz space fractional diffusion equations. Our breakthrough is developing an algorithm to form stiffness matrix on unstructured triangular meshes, which can help us to deal with space fractional terms on any convex domain. The stability and convergence of the scheme are also discussed. Numerical examples are given to verify accuracy and stability of our scheme., 30 pages, 10 figures
- Published
- 2016
37. Comparative metabolic responses and adaptive strategies of wheat (Triticum aestivum) to salt and alkali stress
- Author
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Xu Xia, Rui Guo, Zongze Yang, Qi Liu, HaoRu Li, Feng Li, Changrong Yan, Xiuli Zhong, and Long Zhao
- Subjects
Osmotic shock ,Free ions ,Sodium ,Salt stress ,chemistry.chemical_element ,Plant Science ,Growth ,Biology ,Alkalies ,Sodium Chloride ,Photosynthesis ,chemistry.chemical_compound ,Nutrient ,Osmotic Pressure ,Stress, Physiological ,Metabolites ,Osmotic pressure ,Food science ,Triticum ,Metabolism ,Salt Tolerance ,Phosphate ,Salinity ,Agronomy ,chemistry ,Metal elements ,Wheat ,Alkali stress ,Research Article - Abstract
Background It is well known that salinization (high-pH) has been considered as a major environmental threat to agricultural systems. The aim of this study was to investigate the differences between salt stress and alkali stress in metabolic profiles and nutrient accumulation of wheat; these parameters were also evaluated to determine the physiological adaptive mechanisms by which wheat tolerates alkali stress. Results The harmful effect of alkali stress on the growth and photosynthesis of wheat were stronger than those of salt stress. High-pH of alkali stress induced the most of phosphate and metal ions to precipitate; as a result, the availability of nutrients significantly declined. Under alkali stress, Ca sharply increased in roots, however, it decreased under salt stress. In addition, we detected the 75 metabolites that were different among the treatments according to GC-MS analysis, including organic acids, amino acids, sugars/polyols and others. The metabolic data showed salt stress and alkali stress caused different metabolic shifts; alkali stress has a stronger injurious effect on the distribution and accumulation of metabolites than salt stress. These outcomes correspond to specific detrimental effects of a highly pH environment. Conclusions Ca had a significant positive correlation with alkali tolerates, and increasing Ca concentration can immediately trigger SOS Na exclusion system and reduce the Na injury. Salt stress caused metabolic shifts toward gluconeogenesis with increased sugars to avoid osmotic stress; energy in roots and active synthesis in leaves were needed by wheat to develop salt tolerance. Alkali stress (at high pH) significantly inhibited photosynthetic rate; thus, sugar production was reduced, N metabolism was limited, amino acid production was reduced, and glycolysis was inhibited. Electronic supplementary material The online version of this article (doi:10.1186/s12870-015-0546-x) contains supplementary material, which is available to authorized users.
- Published
- 2015
38. Numerical algorithm for three-dimensional space fractional advection diffusion equation
- Author
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Yufeng Nie, Jungang Wang, Zongze Yang, Zhanbin Yuan, and Jiahui Hu
- Subjects
Diffusion equation ,Discretization ,Dimension (vector space) ,Anomalous diffusion ,Mathematical analysis ,Volume of fluid method ,Numerical solution of the convection–diffusion equation ,Convection–diffusion equation ,Algorithm ,Mathematics ,Fractional calculus - Abstract
Space fractional advection diffusion equations are better to describe anomalous diffusion phenomena because of non-locality of fractional derivatives, which causes people to confront great trouble in problem solving while enjoying the convenience from mathematical modelling, especially in high dimensional cases. In this paper, we solve the three-dimensional problem by the process of dimension by dimension, which can be achieved through a predictor-corrector algorithm. In time discretization, Crank-Nicolson scheme is adopted to match second-order difference operator of the space direction. Then, the efficiency of this method is demonstrated by some numerical examples finally.
- Published
- 2017
39. Drought Enhances Nitrogen Uptake and Assimilation in Maize Roots.
- Author
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Huan Wang, Zongze Yang, Yanan Yu, Siyu Chen, Zhang He, Yong Wang, Li Jiang, Guan Wang, Chunwu Yang, Bao Liu, and Zhian Zhang
- Abstract
Nitrogen metabolism has important roles in plant drought tolerance, and higher N uptake can enhance plant drought tolerance. The aim of this study was to investigate the role of N metabolism regulation in maize drought tolerance. We measured the expression of genes known to be involved in N uptake and assimilation, together with various photosynthetic parameters, and nutrient content, in different tissues from maize plants exposed to water deficit conditions. Different tissues displayed significant differences in their regulation of N metabolism during the adaptation of maize plants to drought stress. The impact of drought on ammonium (NH
4 + ) assimilation was much greater in old and mature leaves than in younger leaves. Correspondingly, drought had a smaller effect on photosynthesis in young leaves than in old and mature leaves, suggesting that the disruption of NH4 + assimilation in the latter may be attributable to a greater reduction in photosynthesis. In roots, we found that drought stress dramatically enhanced the expression levels of nearly all genes involved in N uptake and assimilation, including AMT1;3, AMT1;1b, NRT1;2 and NRT2;5, NR, GS2, and GS1;2. We suggest that increasing the expression of AMT1;1b, AMT1;3, NRT1;2, and NRT2;5 in maize roots under drought condition will increase N uptake and promote rapid accumulation of amino acids. The data revealed that AMT1;1b, AMT1;3, NRT1;2, and NRT2;5 may play important roles in drought tolerance of maize. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
40. Comparative metabolic responses and adaptive strategies of wheat (Triticum aestivum) to salt and alkali stress.
- Author
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Rui Guo, Zongze Yang, Feng Li, Changrong Yan, Xiuli Zhong, Qi Liu, Xu Xia, Haoru Li, and Long Zhao
- Subjects
- *
WHEAT , *EFFECT of salt on plants , *SOIL salinization , *PLANT metabolites , *PHOTOSYNTHESIS - Abstract
Background: It is well known that salinization (high-pH) has been considered as a major environmental threat to agricultural systems. The aim of this study was to investigate the differences between salt stress and alkali stress in metabolic profiles and nutrient accumulation of wheat; these parameters were also evaluated to determine the physiological adaptive mechanisms by which wheat tolerates alkali stress. Results: The harmful effect of alkali stress on the growth and photosynthesis of wheat were stronger than those of salt stress. High-pH of alkali stress induced the most of phosphate and metal ions to precipitate; as a result, the availability of nutrients significantly declined. Under alkali stress, Ca sharply increased in roots, however, it decreased under salt stress. In addition, we detected the 75 metabolites that were different among the treatments according to GC-MS analysis, including organic acids, amino acids, sugars/polyols and others. The metabolic data showed salt stress and alkali stress caused different metabolic shifts; alkali stress has a stronger injurious effect on the distribution and accumulation of metabolites than salt stress. These outcomes correspond to specific detrimental effects of a highly pH environment. Conclusions: Ca had a significant positive correlation with alkali tolerates, and increasing Ca concentration can immediately trigger SOS Na exclusion system and reduce the Na injury. Salt stress caused metabolic shifts toward gluconeogenesis with increased sugars to avoid osmotic stress; energy in roots and active synthesis in leaves were needed by wheat to develop salt tolerance. Alkali stress (at high pH) significantly inhibited photosynthetic rate; thus, sugar production was reduced, N metabolism was limited, amino acid production was reduced, and glycolysis was inhibited. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
41. Evolution of physiological responses to salt stress in hexaploid wheat.
- Author
-
Chunwu Yang, Long Zhao, Huakun Zhang, Zongze Yang, Huan Wang, Shanshan Wen, Chunyu Zhang, Rustgicd, Sachin, von Wettsteincde, Diter, and Bao Liu
- Subjects
EFFECT of stress on plants ,WHEAT ,SALT ,BIOLOGICAL evolution ,GENETICS ,PLANT development ,PLANT genetics ,PHYSIOLOGY - Abstract
Hexapioid bread wheat (Triticum aestivum U genome BBAADD) is generally more salt tolerant than its tetraploid wheat progenitor (Triticum turgidum L). However, little is known about the physiological basis of this trait or about the relative contributions of allohexaploidization and subsequent evolutionary genetic changes on the trait development. Here, we compared the salt tolerance of a synthetic allohexaploid wheat (neo-6x) with its tetraploid (T. turgidum; BBAA) and diploid (Aegilops tauschii; DD) parents, as well as a natural hexapioid bread wheat (nat-6x). We studied 92 morphophysiological traits and analyzed homeologous gene expression of a major salt-tolerance gene High-Affinity K
+ Transporter 1;5 (HKTV.S). We observed that under salt stress, neo-6x exhibited higher fitness than both of its parental genotypes due to inheritance of favorable traits like higher germination rate from the 4x parent and the stronger root Na+ retention capacity from the 2x parent. Moreover, expression of the D-subgenome HKTV.5 homeolog, which is responsible for Na+ removal from the xylem vessels, showed an immediate transcriptional reprogramming following allohexaploidization, i.e., from constitutive high basal expression in Ae. tauschii (2x) to salt-induced expression in neo-6x. This phenomenon was also witnessed in the nat-6x. An integrated analysis of 92 traits showed that, under salt-stress conditions, neo-6x resembled more closely the 2x than the 4x parent, suggesting that the salt stress induces enhanced expressivity of the D-subgenome homeologs in the synthetic hexapioid wheat. Collectively, the results suggest that condition-dependent functionalization of the subgenomes might have contributed to the wide-ranging adaptability of natural hexapioid wheat. [ABSTRACT FROM AUTHOR]- Published
- 2014
- Full Text
- View/download PDF
42. Antibiotic Sensitivity Test and Detection of Sulfonamide Resistance Gene Sul2 in Escherichia coli Isolates from Swine.
- Author
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Yanying ZHANG, Fang XIANG, Rui GUO, Zhaoxing ZHANG, Qiumei SHI, Yuqin LIU, Cairan YANG, Zongze YANG, Guangping GAO, Guisheng GAO, Zhi PENG, and Xun SUO
- Subjects
ESCHERICHIA coli ,BACTERIAL genetics ,SULFINAMIDES ,ORGANOSULFUR compounds ,PHYSIOLOGICAL effects of antibiotics ,POLYMERASE chain reaction ,THERAPEUTICS - Abstract
[Objective] This study aimed to analyze antibiotic sensitivity and detect sulfonamide resistance gene Sul2 in 17 Escherichia coli isolates from swine. [Method] The antibiotic sensitivity of 17 E. coli isolates from swine was analyzed with Kirby-Bauer disk diffusion method. Sulfonamide resistance gene Sul2 was detected by PCR amplification with the extracted genomic DNA as a template. [Result] The 17 swine-derived E. coli isolates from different regions were resistant to various antibiotics and exhibited different multi-antibiotic resistance phenotypes, including nine isolates resistant to sulfamethoxazole, seven isolates resistant to oxacillin, ten isolates resistant to cefazolin and eight isolates resistant to erythromycin. Sulfonamide resistance gene Sul2 was successfully amplified from genomic DNA of E. coli isolates. The PCR results were basically consistent with antibiotic resistance phenotypes of these strains. [Conclusion] Sul2 gene was widespread in swine-derived E. coli, which was closely associated with sulfonamide resistance phenotypes of E. coli. [ABSTRACT FROM AUTHOR]
- Published
- 2016
43. ERROR ESTIMATES FOR THE LAPLACE INTERPOLATION ON CONVEX POLYGONS.
- Author
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WEIWEI ZHANG, LONG HU, ZONGZE YANG, and YUFENG NIE
- Subjects
- *
INTERPOLATION , *MATHEMATICAL analysis - Abstract
In the natural element method (NEM), the Laplace interpolation error estimate on convex planar polygons is proved in this study. The proof is based on bounding gradients of the Laplace interpolation for convex polygons which satisfy certain geometric requirements, and has been divided into several parts that each part is bounded by a constant. Under the given geometric assumptions, the optimal convergence estimate is obtained. This work provides the mathematical analysis theory of the NEM. Some numerical examples are selected to verify our theoretical result. [ABSTRACT FROM AUTHOR]
- Published
- 2021
44. Numerical algorithm for three-dimensional space fractional advection diffusion equation.
- Author
-
Jiahui Hu, Jungang Wang, Zhanbin Yuan, Zongze Yang, and Yufeng Nie
- Published
- 2017
- Full Text
- View/download PDF
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