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This study explored the mental health of students in smoke-free universities and the influence of creative arts therapy during COVID-19 pandemic period. 1) The survey was conducted from March to April, 2020, and students in smoke-free universities were invited to fill out and forward the questionnaire through social software such as QQ and WeChat. The subjects of the survey are 800 students studying in smoke-free colleges and universities in South China. 2) The experimental research method was adopted. 40 students in smoke-free universities suffering from psychological stress and depression caused by COVID-19 pandemic were divided into 20 experimental groups and 20 control groups. The control group received no intervention treatment, while the experimental group received creative arts therapy. The survey data of mental health of students in smoke-free universities, mental health assessment standard data and self-esteem scale (SES) were observed. Results: A total of 850 questionnaires were collected, of which 839 were valid, and the effective response rate was 98.7%. As for the scores of the new psychological status of students in smoke-free universities during covid-19 pandemic period and mental health of students in smoke-free universities, the slight degree accounted for the highest proportion (39.7%), followed by the moderate degree of 34.2%. And 47% of the respondents felt lonely, decadent, irritable, emotionally fluctuating and difficult to concentrate. the results of self-esteem scale (SES) showed that there was no significant difference between the two groups before intervention (t=1.782, P=0.08>0.05). After intervention, the score of the study group was 42.74±2.69 points, which was significantly higher than that of the control group (36.11±4.58 points), and the difference was statistically significant (Z=-1.192, P=0.04

Additional file 2: Supplementary Figure 1. Sera levels of several proteins in response and resistant to nCRT groups of rectal cancer. (A-B) Scatter plots of baseline sera GELS and HEP2 concentrations obtained from pCR and non-pCR patients using the PRM. (C-D) Scatter plots of baseline sera GELS and HEP2 concentrations obtained from the responding and the non-responding patients using the PRM. (E-F) Scatter plots of post-nCRT sera HEP2 and APOH concentrations obtained from the responding and the non-respondingpatients using the PRM.

To achieve the goal of “carbon peak, carbon neutralization”, the proportion of renewable energy access will continue to increase, which will bring a severe test to the balance adjustment ability of the new power system, and the demand for flexible adjustment and real-time balance of the power system will continue to increase. However, pumped storage power stations and grid-side energy storage facilities, which are flexible peak-shaving resources, have relatively high investment and operation costs. 5G base station energy storage to participate in demand response can share the cost of energy storage system construction by power companies and communication operators to achieve a win-win situation between the communication system and the power system. Based on the analysis of the feasibility and incremental cost of 5G communication base station energy storage participating in demand response projects, combined with the interest interaction mechanism of all parties in the project, this paper proposes a business model for 5G energy storage to participate in the grid collaboration and interaction to improve the profit model of various market players, thereby promoting the penetration rate of the project.