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Your search keyword '"Zhou, Fu-Peng"' showing total 4 results
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4 results on '"Zhou, Fu-Peng"'

2. Amyloid peptide hydrogels via formation of coordination polymers with Ag+ by its core peptide equipped with a C-cysteine.

Author

Wang, Qian, Zhou, Fu-Peng, Tao, Dan-Dan, Wei, Jin-Hong, Cai, Rui, and Jiang, Yun-Bao

Subjects
*PEPTIDES, *C-terminal residues, *AMYLOID, *AMYLOID beta-protein
Abstract

We report that the core sequence of amyloid β (Aβ) peptide, KLVFF, when equipped with a C-terminal cysteine residue, exhibited an extremely low minimum hydrogelation concentration of 0.05 wt% in the presence of Ag+ in pH 5 buffer, with this concentration 2 orders of magnitude lower than that of the pentapeptide itself. The CD signal of the Ag+- L -KLVFFC hydrogel was observed to be sensitive to the early-stage aggregation of amyloid β peptide. [ABSTRACT FROM AUTHOR]

Published
2023
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4. Amyloid peptide hydrogels via formation of coordination polymers with Ag + by its core peptide equipped with a C-cysteine.

Author

Wang Q, Zhou FP, Tao DD, Wei JH, Cai R, and Jiang YB

Subjects
Polymers, Hydrogels, Peptide Fragments chemistry, Amyloid chemistry, Amyloid beta-Peptides chemistry, Cysteine
Abstract

We report that the core sequence of amyloid β (Aβ) peptide, KLVFF, when equipped with a C-terminal cysteine residue, exhibited an extremely low minimum hydrogelation concentration of 0.05 wt% in the presence of Ag + in pH 5 buffer, with this concentration 2 orders of magnitude lower than that of the pentapeptide itself. The CD signal of the Ag + -L-KLVFFC hydrogel was observed to be sensitive to the early-stage aggregation of amyloid β peptide.

Published
2023
Full Text
View/download PDF

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