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1. The synthesis, discovery, and development of a highly promising class of microtubule....

Author

Ting-Chao Chou, O'Connor, Owen A., Tong, William P., Yongbiao Guan, Zui-Gou Zhang, Stachel, Shawn J., Chulbom Lee, and Danishefsky, Samuel J.

Subjects
STABILIZING agents, CANCER
Abstract

Examines the curative effect of desoxyepothilones B (dEpoB) and F (dEpoF) against human tumor xenografts in mice. Synthesis of microtubule stabilizing agents; Pharmacologic properties of dEopB; Production of nonmultiple drug-resistant human lung carcinoma A549 cells.

Published
2001
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