62 results on '"cumplimiento del paciente"'
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2. Efectividad de las tecnologías de la información y comunicación en la adherencia terapéutica de pacientes con Hipertensión Arterial y Diabetes Mellitus
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Diana Patricia González-Ruiz, Daniela Alejandra Getial-Mora, María Alejandra Higidio-Miranda, and Sandra Milena Hernández-Zambrano
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cumplimiento y adherencia al tratamiento ,cumplimiento del paciente ,tecnología de la información ,ciencia de la información ,hipertensión arterial ,diabetes mellitus ,Nursing ,RT1-120 ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Introducción: La hipertensión arterial y la diabetes mellitus son dos de las principales causas de morbimortalidad, siendo las precursoras de la enfermedad renal crónica, catalogándose como un problema de salud pública que afecta a uno de cada diez adultos en el mundo. La falta de cumplimiento al tratamiento es la mayor causa de fracaso en los programas de promoción y prevención, con esta revisión sistemática se busca aportar a los profesionales de enfermería evidencia científica a través del uso de las tecnologías de la información y la comunicación que permitan mejorar la adherencia terapéutica. Objetivo: Identificar la efectividad de las tecnologías de la información y la comunicación en la adherencia terapéutica en personas con Hipertensión Arterial y Diabetes Mellitus. Material y Método. Se realizó una revisión sistemática de literatura en las bases de datos CUIDEN, CINAHL, COCHRANE, LILACS, PUBMED y OVID NURSING. Después de aplicar filtros de selección y listas de verificacion de calidad metodológica se obtuvieron 18 artículos para análisis, 12 ensayos clínicos aleatorizados, 3 estudios cuasi-experimentales y 3 revisiones sistemáticas. Se clasificó el nivel de evidencia de los estudios según el instituto Joanna Briggs. Resultados. Se establecieron 3 categorías: Intervenciones unicomponente, intervenciones multicomponente y rol de enfermería en el uso de TICs para favorecer la adherencia. Conclusiones. Dentro del cuidado de la salud actualmente hay hallazgos iniciales que apoyan la efectividad del uso de las tecnologías de la información y la comunicación convirtiéndola en una herramienta que favorece la adherencia al tratamiento en pacientes con hipertensión arterial y diabetes mellitus.
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- 2020
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3. Efectividad de las tecnologías de la información y comunicación en la adherencia terapéutica de pacientes con Hipertensión Arterial y Diabetes Mellitus.
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González-Ruiz, Diana Patricia, Getial-Mora, Daniela Alejandra, Higidio-Miranda, María Alejandra, and Hernández-Zambrano, Sandra Milena
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TREATMENT of diabetes ,CINAHL database ,COMMUNICATION ,DRUGS ,HYPERTENSION ,INFORMATION storage & retrieval systems ,MEDICAL databases ,INFORMATION technology ,MEDLINE ,NURSES ,ONLINE information services ,PATIENT compliance ,SYSTEMATIC reviews ,OCCUPATIONAL roles ,TREATMENT effectiveness - Abstract
Copyright of Enfermería Nefrológica is the property of Sociedad Espanola de Enfermeria Nefrologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2020
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4. Barriers Identification as Intervention to Engage Breast Cancer Survivors in Physical Activity.
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André, Nathalie, Pillaud, Marine, Davoust, Aurélien, and Laurencelle, Louis
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BREAST cancer patients , *PHYSICAL activity , *DECISION making , *ONCOLOGY nursing , *PATIENT compliance , *MOTIVATION (Psychology) - Abstract
This study was designed to demonstrate the advantage of adding cancer barriers to components of decision-making in the transtheoretical model (TTM). In study 1, questionnaires were completed by 139 breast cancer survivors including decisional balance, cancer-related barriers and stages of readiness. In study 2, efficiency of directly tackling cancer-related barriers through motivational-style conversation was tested in a quasi-experimental design. From study 1, all decisionmaking variables were related to stages of readiness, but cancer-related barriers were the sole predictors of engagement in physical activity. Out of the three groups of study 2, only the group with motivational-style conversation displayed a significant progress for engagement in physical activity. Demonstrating that cancer-related barriers predict stage of change above the effects of the two components of decisional balance provides a validation of positions that put cancer-related barriers as uniquely related to stages of change, and suggests that adding them in decision making variables in TTM's model can provide a genuinely new contribution to the understanding of physical activity adherence. Regarding implication for cancer survivors, these results suggest that in order to stimulate progress in early stages of change, a greater emphasis may be needed on reducing cancer-related barriers. [ABSTRACT FROM AUTHOR]
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- 2018
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5. Adaptaciones de la dispensación hospitalaria a pacientes con hemofilia durante la pandemia COVID-19 en España y su influencia en la adherencia
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Blázquez Ramos,N, Romero Garrido,JA, Bilbao Gómez-Martino,C, González del Valle,L, Herrero Ambrosio,A, and Benedí González,J
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Coronavirus ,cumplimiento del paciente ,adherencia a la medicación ,España ,profilaxis ,hemofilia - Abstract
Resumen Introducción: El estado de alarma decretado por la pandemia del virus SARS COV-2 del 14 de marzo hasta el 21 de junio, ha supuesto un desafío para el área de pacientes externos de los Servicios de Farmacia. Nos centramos en los pacientes con hemofilia que se administran factores de la coagulación de forma crónica para prevenir hemorragias. Objetivos: Analizar durante este periodo el porcentaje de pacientes que han recogido su medicación, han mantenido la adherencia al tratamiento y las barreras encontradas para ello. Cuantificar el número y gravedad de episodios hemorrágicos (EH) sufridos y su relación con la pandemia. Analizar la prevalencia y gravedad de COVID en hemofílicos. Métodos: Uno objetivo, utilizando los registros del hospital y otro subjetivo, mediante encuesta oral durante la consulta de atención farmacéutica presencial o telemática. Resultados: El 80% de los pacientes retiraron medicación durante el periodo de estudio, un 30% en domicilio. El último mes las dispensaciones a domicilio se acompañaron de consulta telemática. Un 24% de pacientes disminuyó su adherencia respecto al 2019. Las principales causas fueron dificultad para acudir al hospital, y percepción de no necesitar tratamiento ante la inactividad. No se registraron más EH o ingresos por causas imputables a la pandemia. No hubo ningún enfermo COVID-19 grave y la incidencia de pacientes con síntomas leves fue similar a la población general. Conclusión: La mayoría de los pacientes con hemofilia pudieron acceder a su medicación. La adherencia se redujo. Los EH no aumentaron por causas atribuibles a la pandemia. La incidencia de COVID-19 fue similar a la población.
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- 2022
6. Habilidades comunicativas de enfermería para conseguir dietas adaptadas efectivas en pacientes paquistaníes con Diabetes mellitus 2.
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Calpe-Cristino, Ainhoa, Fructuoso-González, Elisabeth, Ochando-Aymerich, Montserrat, Fernández-Martín, Iñaki, Rodero-Nuño, Montserrat, Hidalgo-Ortiz, Manuela, Chueco-Ochando, Aida, Pérez-Hervada Maestre, Maria, Grau-Bartomeu, Jordi, and Plaza-Espuña, Isabel
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Introduction: Nursing training in communicative skills can increase compliance and improve dietary control in Diabetes Mellitus-2 (DM-2). Our research group designed an adapted diet for patients from Pakistan with DM-2 where we found an improvement in adherence and dietary compliance. Objectives: Assess the effectivity of an adapted diet for Pakistani patients in the metabolic control of DM2. Evaluate the effectiveness of the diet on diabetic complications. Methodology: Random clinical trial developed in three primary healthcare centers: Besòs, Raval Sud in Barcelona and Fondo in Santa Coloma de Gramanet. Inclusion criteria: adult patients with DM2, Pakistani origin and HbA1c > 8%. This study falls upon professional-patient communication through detailed explanation of the diet.Random consecutive sample. The intervention group received the adapted diet and the control group the usual measures of DM2 control. Preliminary results: Initial phase of the study. We recruited 19 patients. 64.7% have poor metabolic control (HbA1c mean = 9.9, standard deviation = 2.41). Discussion: We appreciate an improvement in nurse-patient communication, better compliance with the recommendations and a patient satisfaction with the first visits. [ABSTRACT FROM AUTHOR]
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- 2017
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7. Efectividad de las tecnologías de la información y comunicación en la adherencia terapéutica de pacientes con Hipertensión Arterial y Diabetes Mellitus
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Sandra Milena Hernández-Zambrano, Diana Patricia González-Ruiz, María Alejandra Higidio-Miranda, and Daniela Alejandra Getial-Mora
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Advanced and Specialized Nursing ,tecnología de la información ,cumplimiento del paciente ,cumplimiento y adherencia al tratamiento ,RT1-120 ,030209 endocrinology & metabolism ,Nursing ,ciencia de la información ,Diseases of the genitourinary system. Urology ,03 medical and health sciences ,hipertensión arterial ,0302 clinical medicine ,Nephrology ,Hipertensión ,diabetes mellitus ,Cooperación del paciente ,030212 general & internal medicine ,RC870-923 - Abstract
espanolIntroduccion: La hipertension arterial y la diabetes mellitus son dos de las principales causas de morbimortalidad, siendo las precursoras de la enfermedad renal cronica, catalogandose como un problema de salud publica que afecta a uno de cada diez adultos en el mundo. La falta de cumplimiento al tratamiento es la mayor causa de fracaso en los programas de promocion y prevencion, con esta revision sistematica se busca aportar a los profesionales de enfermeria evidencia cientifica a traves del uso de las tecnologias de la informacion y la comunicacion que permitan mejorar la adherencia terapeutica. Objetivo: Identificar la efectividad de las tecnologias de la informacion y la comunicacion en la adherencia terapeutica en personas con Hipertension Arterial y Diabetes Mellitus. Material y Metodo. Se realizo una revision sistematica de literatura en las bases de datos CUIDEN, CINAHL, COCHRANE, LILACS, PUBMED y OVID NURSING. Despues de aplicar filtros de seleccion y listas de verificacion de calidad metodologica se obtuvieron 18 articulos para analisis, 12 ensayos clinicos aleatorizados, 3 estudios cuasi-experimentales y 3 revisiones sistematicas. Se clasifico el nivel de evidencia de los estudios segun el instituto Joanna Briggs. Resultados. Se establecieron 3 categorias: Intervenciones unicomponente, intervenciones multicomponente y rol de enfermeria en el uso de TICs para favorecer la adherencia. Conclusiones. Dentro del cuidado de la salud actualmente hay hallazgos iniciales que apoyan la efectividad del uso de las tecnologias de la informacion y la comunicacion convirtiendola en una herramienta que favorece la adherencia al tratamiento en pacientes con hipertension arterial y diabetes mellitus. EnglishIntroduction: Arterial hypertension and diabetes mellitus are two of the main causes of morbidity and mortality, being the precursors of chronic kidney disease Revisiones https://doi.org/10.37551/S2254-28842020003 Efectividad de las tecnologias de la informacion y comunicacion en la adherencia terapeutica de pacientes con Hipertension Arterial y Diabetes Mellitus Diana Patricia Gonzalez-Ruiz, Daniela Alejandra Getial-Mora, Maria Alejandra Higidio-Miranda, Sandra Milena Hernandez-Zambrano Facultad de Enfermeria. Fundacion Universitaria de Ciencias de la Salud. Colombia Como citar este articulo: Gonzalez-Ruiz DP, Getial-Mora DA, Higidio-Miranda MA, Hernandez-Zambrano SM. Efectividad de las tecnologias de la informacion y comunicacion en la adherencia terapeutica de pacientes con Hipertension Arterial y Diabetes Mellitus. Enferm Nefrol. 2020 Ene-Mar;23(1):22-32 Correspondencia: Diana Patricia Gonzalez Ruiz E-mail: dpgonzalez@fucsalud.edu.co 23 23 Enferm Nefrol. 2020 Ene-Mar;23(1):22-32 Gonzalez-Ruiz DP et al. https://doi.org/10.37551/S2254-28842020003 Revisiones and classified as a public health problem that affects one in ten adults in the world. Lack of compliance with treatment is the major cause of failure in promotion programs and prevention. This systematic review seeks to provide scientific evidence to nursing professionals using information and communication technologies that improve therapeutic adherence. Objective: Identify the effectiveness of information and communication technologies in therapeutic adherence in people with Arterial Hypertension and Diabetes Mellitus. Material y Method: A systematic literature review was carried out in the CUIDEN, CINAHL, COCHRANE, LILACS, PUBMED and OVID NURSING databases. After applying the selection criteria and methodological quality checklists, 18 articles were obtained for analysis: 12 randomized clinical trials, 3 quasi-experimental studies and 3 systematic reviews. The level of evidence of the studies was classified according to the Joanna Briggs Institute. Results: Three categories were established: single interventions, multicomponent interventions and nursing role in the use of ICTs to favour adherence. Conclusions: Currently, within health care, there are initial findings that support the effectiveness of the use of information and communication technologies, being a tool that favours therapeutic adherence in patients with arterial hypertension and diabetes mellitus.
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- 2020
8. Clinical outcomes of Ghanaian Buruli ulcer patients who defaulted from antimicrobial therapy.
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Klis, S., Kingma, R. A., Tuah, W., Werf, T. S., and Stienstra, Y.
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BURULI ulcer , *STREPTOMYCIN , *RIFAMPIN , *ANTI-infective agents , *SKIN diseases , *RETROSPECTIVE studies , *GHANAIANS , *DISEASES , *THERAPEUTICS , *ANTIBIOTICS , *COMBINATION drug therapy , *DRUGS , *DRUG administration , *GRAM-positive bacteria , *HOSPITALS , *LONGITUDINAL method , *PATIENT compliance , *WOUND healing , *TREATMENT effectiveness - Abstract
Objectives: Buruli ulcer (BU) is a tropical skin disease caused by infection with Mycobacterium ulcerans, which is currently treated with 8 weeks of streptomycin and rifampicin. The evidence to treat BU for a duration of 8 weeks is limited; a recent retrospective study from Australia suggested that a shorter course of antimicrobial therapy might be equally effective. We studied the outcomes of BU in a cohort of Ghanaian patients who defaulted from treatment and as such received less than 8 weeks of antimicrobial therapy.Methods: A number of days of antimicrobial therapy and patient and lesion characteristics were recorded from charts from a cohort of BU patients treated at Nkawie-Toase hospital between 2008 and 2012. Patients who defaulted from treatment were retrieved, and lesion characteristics and functional limitations were recorded.Results: About 54% of patients defaulted from therapy or wound care. Forty-seven defaulters with follow-up completed had received <56 days of antibiotics. 84% of these patients healed after 32 days or less of antibiotics. There appeared to be an increased rate of healing in smaller lesions; 94% of WHO category I lesions had healed after 32 days or less of antibiotics.Conclusion: Although numbers were small, and a potential for bias exists, our findings suggest that a reduction in the duration of antimicrobial therapy in BU in small, early lesions is feasible. These findings can serve as a basis for future well-designed studies. [ABSTRACT FROM AUTHOR]- Published
- 2016
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9. Validation and calibration to Spanish of the Compliance Questionnaire on Rheumatology in a group of Colombian patients on treatment for rheumatoid arthritis
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Viviana Rodríguez, Manuela Tobón, Daniel G. Fernández-Ávila, Melissa Accini, Socorro Moreno, and Juan Martín Gutiérrez
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Rheumatology ,business.industry ,Cumplimiento del paciente ,Medicine ,Patient compliance ,Artritis reumatoide ,Rheumatoid arthritis ,business ,Humanities ,Adherencia a medicamentos ,Medication adherence - Abstract
RESUMEN Introducción: La adherencia al tratamiento es uno de los pilares para lograr el control de cualquier enfermedad, y esto aplica también en la artritis reumatoide. Existen diferentes formas de evaluar el grado de adherencia, siendo las escalas de medición uno de los métodos más usados por su facilidad en aplicación y bajo costo. El objetivo de este estudio fue traducir y validar el Compliance Questionnaire on Rheumatology (CQR) al español y calibrar los puntajes de acuerdo con la actividad de la enfermedad medida mediante DAS-28. Materiales y métodos: En la primera fase del estudio se llevó a cabo el proceso de traducción empleando las guías para la traducción y adaptación cultural de medidas centradas en pacientes. Posteriormente se realizó un proceso de aclaración cognoscitiva. Finalmente se llevó a cabo un estudio de pruebas diagnósticas para determinar el mejor punto de corte para el puntaje de la escala CQR en la identificación del nivel de adherencia al tratamiento antirreumático en pacientes con artritis reumatoide, empleando el DAS 28 como subrogado de adherencia. Resultados: Un total de 233 pacientes con edad promedio de 46,3 (± 13,9) años y tiempo promedio de evolución de enfermedad de 11,2 (±9,6) años. El punto de corte del CQR para establecer adherencia al tratamiento fue de 80,7, con lo cual se obtuvo una sensibilidad del 80,2% (IC 95%: 71,9-86,9%) y una especificidad del 72,3% (IC 95%: 63,1-80,4%). Con este punto de corte se estableció que el 43,8% (n = 102) de los pacientes eran adherentes a la terapia antirreumática oral. Conclusión: Se desarrolló una versión en español del CQR y se calibraron los puntos de corte obteniendo una herramienta práctica y de rápida aplicación clínica, con aceptables sensibilidad y especificidad. ABSTRACT Introduction: Adherence to treatment is one of the pillars to achieve control of any disease and this also applies to rheumatoid arthritis. There are different ways to assess the level of adherence, and measurement scales are one of the methods most used due to their easy application and low cost. The aim of this study was to translate and validate the Compliance Questionnaire on Rheumatology (CQR) to Spanish and calibrate the scores according to the activity of the disease measured by the DAS-28. Materials and methods: The translation process was carried out in the first phase of the study using guidelines for translation and cultural adaptation of measures focused on patients. This was followed by cognitive clarification process. Finally, a study of diagnostic tests was carried out to determine the best cut-off point for the score on the CQR scale for identifying the level of adherence to rheumatic therapy in patients with rheumatoid arthritis using the DAS-28 as subrogated adherence. Results: The study included 233 patients, with a mean age of 46.3 (±13.9) years and mean time with the disease of 11.2 (±9.6) years. The CQR cut-off to establish adherence to treatment was 80.7. This achieved a sensitivity of 80.2% (95% CI: 71.9-86.9%) and specificity of 72.3% (95% CI: 63.1-80.4%). With this cut-off point, it was established that there was 43.8% (n = 102) patient adherence to oral rheumatic therapy. Conclusion: CQR Spanish version of the CQR was developed and calibrated obtaining a practical tool, with acceptable sensitivity and specificity.
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- 2020
10. Association of Adherence to Specific Mediterranean Diet Components and Cardiorespiratory Fitness in Young Adults
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Josep A. Tur, Mª José Santi-Cano, Amelia Rodríguez Martín, José Pedro Novalbos-Ruiz, María Ángeles Bernal-Jiménez, Maria del Mar Bibiloni, Biomedicina, Biotecnología y Salud Pública, and Enfermería y Fisioterapia
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Male ,Adult ,cumplimiento del paciente ,Waist ,Mediterranean diet ,humanos ,lcsh:TX341-641 ,nuts ,Diet, Mediterranean ,Diet Surveys ,Article ,fenómenos fisiológicos nutricionales de los deportes ,encuestas sobre dietas ,Young Adult ,Surveys and Questionnaires ,Humans ,Medicine ,Young adult ,Students ,mediterranean diet adherence ,Mediterranean diet adherence ,conducta alimentaria ,Nutrition and Dietetics ,cardiorespiratory fitness ,dieta ,business.industry ,VO2 max ,Cardiorespiratory fitness ,Feeding Behavior ,adulto ,Dietary pattern ,Healthy diet ,Diet ,Sports Nutritional Physiological Phenomena ,adulto joven ,Cross-Sectional Studies ,Spain ,Patient Compliance ,Female ,estudiantes ,Diet, Healthy ,business ,Body mass index ,lcsh:Nutrition. Foods and food supply ,estudios transversales ,Food Science ,Demography - Abstract
Objective: Cardiorespiratory fitness (CRF) and a healthy diet may be part of an overall healthy lifestyle. The association between cardiorespiratory fitness and adherence to an overall Mediterranean Diet (MedD) pattern and specific MedD foods has been assessed. Design: Subjects completed a lifestyle survey and dietary pattern, using the validated MedD Adherence 14-item questionnaire and two self-reported 24-h dietary recalls. Participants&rsquo, height, body weight, waist circumference (WC), and CRF (maximum oxygen uptake, VO2max, ml/kg/min) were measured. Setting: University of Cá, diz, Spain. Subjects: A sample of young adults (n = 275, 22.2 ±, 6.3 years). Results: Mean VO2max was 43.9 mL/kg/min (SD 8.5 mL/kg/min). Most participants had healthy CRF (75.9%). The average MedD score was 6.2 points (SD 1.8 points). Participants who consumed more servings of nuts had higher VO2max. Those who showed low CRF performed less physical activity (PA) and had a higher body mass index (BMI) and WC compared with those classified as having healthy CRF. Nut consumption was positively associated with VO2max (&beta, = 0.320, 95% CI 2.4, 10.7, p <, 0.002), adjusting for sex, age, smoking PA, BMI, WC, and energy intake, showing the subjects who consumed more nuts were fitter than young adults who consumed less. Conclusions: CRF is positively associated with nut consumption but not with the overall MedD pattern and all other MedD foods in the young adults. The subjects who consumed more servings of nuts were fitter than young adults who consumed less. Moreover, fitter subjects performed more PA and had a lower BMI and WC than those who had lower fitness levels.
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- 2020
11. Compliance and Utility of a Smartphone App for the Detection of Exacerbations in Patients With Chronic Obstructive Pulmonary Disease: Cohort Study
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Juan Luis Rodríguez Hermosa, Carlos Antonio Amado Diago, Luis Puente Maestu, Francisco Javier Callejas González, Rosa Malo De Molina Ruiz, Myriam Calle Rubio, Manuel Fuentes Ferrer, Antonia Fuster Gomila, and Jose Luis Álvarez Sala-Walther
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Male ,medicine.medical_specialty ,Chronic condition ,cumplimiento del paciente ,Exacerbation ,humanos ,Health Informatics ,Disease ,Information technology ,compliance ,chronic obstructive pulmonary disease ,03 medical and health sciences ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,estudios prospectivos ,Medicine ,Humans ,030212 general & internal medicine ,Prospective Studies ,mHealth ,Depression (differential diagnoses) ,COPD ,Original Paper ,mobile phone ,business.industry ,medicine.disease ,T58.5-58.64 ,Comorbidity ,Mobile Applications ,030228 respiratory system ,Emergency medicine ,Patient Compliance ,Female ,aplicaciones en aparatos electrónicos portátiles ,Smartphone ,Public aspects of medicine ,RA1-1270 ,business ,Cohort study - Abstract
Background: In recent years, mobile health (mHealth)-related apps have been developed to help manage chronic diseases. Apps may allow patients with a chronic disease characterized by exacerbations, such as chronic obstructive pulmonary disease (COPD), to track and even suspect disease exacerbations, thereby facilitating self-management and prompt intervention. Nevertheless, there is insufficient evidence regarding patient compliance in the daily use of mHealth apps for chronic disease monitoring. Objective: This study aimed to provide further evidence in support of prospectively recording daily symptoms as a useful strategy to detect COPD exacerbations through the smartphone app, Prevexair. It also aimed to analyze daily compliance and the frequency and characteristics of acute exacerbations of COPD recorded using Prevexair. Methods: This is a multicenter cohort study with prospective case recruitment including 116 patients with COPD who had a documented history of frequent exacerbations and were monitored over the course of 6 months. At recruitment, the Prevexair app was installed on their smartphones, and patients were instructed on how to use the app. The information recorded in the app included symptom changes, use of medication, and use of health care resources. The patients received messages on healthy lifestyle behaviors and a record of their cumulative symptoms in the app. There was no regular contact with the research team and no mentoring process. An exacerbation was considered reported if medical attention was sought and considered unreported if it was not reported to a health care professional. Results: Overall, compliance with daily records in the app was 66.6% (120/180), with a duration compliance of 78.8%, which was similar across disease severity, age, and comorbidity variables. However, patients who were active smokers, with greater dyspnea and a diagnosis of depression and obesity had lower compliance (P, The authors thank the investigators, Francisco Javier Agustin Martinez, Pulmonology Department, Complejo Hospitalario U de Albacete, and Walther Ivan Giron Matute, Pulmonology Department, Hospital U Gregorio Maranon Madrid, Spain, who participated in the Prevexair study. The authors also thank Astra Zeneca for its financial support to carry out the study. This study has been promoted and sponsored by the Spanish Society of Pneumology and Thoracic Surgery. The financers had no role in study design, data collection, analysis, and decision to publish or in the preparation of this manuscript. This does not alter our adherence to the policies of the Journal of Medical Internet Research on sharing data and materials.
- Published
- 2020
12. Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study
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Josep A. Tur, Itziar Abete, José J. Gaforio, Jordi Salas-Salvadó, Nerea Becerra-Tomás, Francisco J. Tinahones, Albert Goday, Xavier Pintó, Maria Dolors Zomeño, Julia Wärnberg, Alejandro Oncina-Canovas, Carmen Saiz, Jessica Pérez-López, Dolores Corella, Clotilde Vázquez, Lucas Tojal-Sierra, Leyre Notario-Barandiaran, Marga Morey, Lidia Daimiel, Aurora Bueno-Cavanillas, José Manuel Santos-Lozano, José Lapetra, F. Javier Basterra-Gortari, Julia Muñoz, Alicia Julibert, Marian Martín, M. Rosa Bernal-Lopez, Sara Castro-Barquero, Ana Galera, Josep Vidal, Vicente Martín-Sánchez, Miguel Ruiz-Canela, Maria C Belló-Mora, Emilio Ros, Ignacio M. Gimenez-Alba, Antonio García Ríos, Tamara Casañas-Quintana, Ángel M. Alonso-Gómez, Jesús García-Gavilán, Josep Basora, Jesús Vioque, Ramon Estruch, Dora Romaguera, Luis Serra-Majem, Cesar I Fernandez-Lazaro, Pilar Matía-Martín, Escarlata Angullo-Martinez, Cristina Bouzas, Carmen Sayón-Orea, J. Alfredo Martínez, Olga Castañer, Maria del Mar Bibiloni, [Bouzas,C, Bibiloni,MM, Julibert,A, Ruiz-Canela,M, Salas-Salvadó,J, Corella,D, Zomeño,MD, Romaguera,D, Alonso-Gómez,ÁM, Wärnberg,J, Martínez,JA, Serra-Majem,L, Estruch,R, Tinahones,FJ, Lapetra,J, Pintó,X, García Ríos,A, Vázquez,C, Ros,E, Fernandez-Lázaro,CI, Becerra-Tomás,N, Gimenez-Alba,IM, Muñoz,J, Morey,M, Pérez-López,J, Abete,I, Casañas-Quintana,T, Castro-Barquero,S, Bernal-López,MR, Santos-Lozano,JM, Galera,A, Angullo-Martinez,E, Basterra-Gortari,FJ, Basora,J, Saiz,C, Castañer,O, Martín,M, Belló-Mora,MC, Sayón-Orea,C, García-Gavilán,J, Goday,A, Tur,JA] CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. [Bouzas,C, Tojal-Sierra,L, Tur,JA] Research Group on Community Nutrition & Oxidative Stress, University of Balearic Islands, Guillem Colom Bldg, Campus, Palma de Mallorca, Spain. [Bouzas,C, Tur,JA] Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain. [Ruiz-Canela,M, Sayón-Orea,C] Department of Preventive Medicine and Public Health, IdISNA, University of Navarra, Pamplona, Spain. [Salas-Salvadó,J, García-Gavilán,J] Universitat Rovira i Virgili, Department of Biochemistry and Biotechnology, Human Nutrition Unit, Reus, Spain. [Salas-Salvadó,J] Institut d’Investigació Sanitària Pere Virgili (IISPV), Reus, Spain. [Corella,D, Saiz,C] Department of Preventive Medicine, University of Valencia, Valencia, Spain. [Zomeño,MD, Goday,A] Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar de Investigaciones Médicas Municipal d’Investigació Mèdica (IMIM), Barcelona, Spain. [Zomeño,MD] Blanquerna School of Health Sciences, Universitat Ramon Llull, Barcelona, Spain. [Vioque,J, Oncina-Canovas,A, Notario-Barandiarán,L] Unit of Nutritional Epidemiology, Miguel Hernández University, ISABIAL-UMH, Alicante, Spain. [Vioque,J, Bueno-Cavanillas,A, Gaforio,JJ, Notario-Barandiarán,L] CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. [Alonso-Gómez,ÁM, Belló-Mora,MC] Bioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain. [Wärnberg,J, Pérez-López,J] Department of Nursing, School of Health Sciences, University of Málaga-IBIMA, Málaga, Spain. [Martínez,JA] Precision Nutrition Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain. [Martínez,JA, Abete,I] Department of Nutrition, Food Sciences, and Physiology, Center for Nutrition Research, University of Navarra, Pamplona, Spain. [Serra-Majem,L, Casañas-Quintana,T] Institute for Biomedical Research, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain. [Estruch,R, Castro-Barquero,S] Department of Internal Medicine, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain. [Tinahones,FJ, Bernal-López,MR] Virgen de la Victoria Hospital, Department of Endocrinology, Biomedical Research Institute of Málaga (IBIMA), University of Málaga, Málaga, Spain. [Lapetra,J, Santos-Lozano,JM] Department of Family Medicine, Research Unit, Distrito Sanitario Atención Primaria Sevilla, Sevilla, Spain. [Pintó,X, Galera,A] Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain. [García Ríos,A] Lipids and Atherosclerosis Unit, Department of Internal Medicine, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain. [Bueno-Cavanillas,A] Department of Preventive Medicine, University of Granada, Granada, Spain. [Gaforio,JJ] Department of Health Sciences, Centro de Estudios Avanzados en Olivar y Aceites de Oliva, University of Jaen, Jaen, Spain. [Matía-Martín,P] Department of Endocrinology and Nutrition, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), Madrid, Spain. [Daimiel,L] Nutritional Genomics and Epigenomics Group, IMDEA Food, CEI UAM + CSIC, Madrid, Spain. [Martín-Sánchez,V] CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. [Martín-Sánchez,V] Institute of Biomedicine (IBIOMED), University of León, León, Spain. [Vidal,J] Department of Endocrinology, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain. [Vázquez,C] Department of Endocrinology, Fundación Jiménez-Díaz, Madrid, Spain. [Ros,E] Lipid Clinic, Department of Endocrinology and Nutrition, Institut d’Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain. [Angullo-Martinez,E] Escola Graduada Primary Health Care Center, IBSalut, Palma de Mallorca, Spain. [Basterra-Gortari,FJ, Sayón-Orea,C] Servicio Navarro de Salud, Osasunbidea, Pamplona, Spain., The PREDIMED-Plus trial was supported by the official funding agency for biomedical research of the Spanish government, ISCIII, through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (five coordinated FIS projects led by J.S.-S. and J.Vidal, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, and PI19/01332, the Especial Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to J.S.-S., the European Research Council (Advanced Research Grant 2013–2018, 340918) to Miguel Ángel Martínez-González, the Recercaixa Grant to J.S.-S. (2013ACUP00194), Grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016, and PI0137/2018), a Grant from the Generalitat Valenciana (PROMETEO/2017/017), a SEMERGEN Grant, EU-COST Action CA16112, a Grant of support to research groups no. 35/2011 from the Balearic Islands Government, Grants from Balearic Islands Health Research Institute (IDISBA), funds from the European Regional Development Fund (CIBEROBN CB06/03 and CB12/03) and from the European Commission (EAT2BENICE_H2020_SFS2016). M. Rosa Bernal-López was supported by 'Miguel Servet Type I' program (CP15/00028) from the ISCIII-Madrid (Spain), cofinanced by the European Regional Development Fund. Jordi Salas-Salvadó is partially supported by ICREA under the ICREA Academia programme. Cristina Bouzas received a Fernando Tarongí Bauzà PhD Grant. I.M Gimenez-Alba received a grant FPU from the Ministry of Science, Innovation and Univesities (reference FPU 18/01703). The funding sponsors had no role in the design of the study, in the collection, analyses, or interpretation of the data, and in the writing of the manuscript, and in the decision to publish the results.
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Male ,Mediterranean diet ,Obesidad ,ejercicio físico ,Body Mass Index ,Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] ,0302 clinical medicine ,Surveys and Questionnaires ,Antineoplastic Combined Chemotherapy Protocols ,Medicine ,mediana edad ,education.field_of_study ,anciano ,Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors [Medical Subject Headings] ,dieta ,protocolos de quimioterapia antineoplásica combinada ,3. Good health ,Older adults ,metotrexato ,programas de reducción de peso ,Obesitat ,lcsh:Nutrition. Foods and food supply ,Personas mayores frágiles ,Ideal weight ,Lifestyles ,Check Tags::Male [Medical Subject Headings] ,lcsh:TX341-641 ,Article ,Estilo de vida ,03 medical and health sciences ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight [Medical Subject Headings] ,Anthropology, Education, Sociology and Social Phenomena::Human Activities::Exercise [Medical Subject Headings] ,ifosfamida ,Humans ,cisplatino ,Ifosfamide ,education ,Exercise ,Aged ,conducta alimentaria ,Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome X [Medical Subject Headings] ,Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings] ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life Style [Medical Subject Headings] ,PREDIMED-Plus ,medicine.disease ,Obesity ,Methotrexate ,Check Tags::Female [Medical Subject Headings] ,Desired weight loss ,Metabolic syndrome ,Cisplatin ,Body mass index ,Demography ,obesity ,cumplimiento del paciente ,humanos ,Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings] ,Ideal Body Weight ,desired weight loss ,Health Care::Health Care Facilities, Manpower, and Services::Health Promotion::Weight Reduction Programs [Medical Subject Headings] ,Overweight ,Diet, Mediterranean ,Mediterranean lifestyle ,Health Care::Health Care Facilities, Manpower, and Services::Health Services::Preventive Health Services::Health Promotion::Healthy People Programs [Medical Subject Headings] ,Weight loss ,030212 general & internal medicine ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Health Behavior::Patient Compliance [Medical Subject Headings] ,Abdominal obesity ,older adults ,Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings] ,2. Zero hunger ,Nutrition and Dietetics ,mediterranean lifestyle ,sobrepeso ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet, Mediterranean [Medical Subject Headings] ,Age Factors ,ideal weight ,Middle Aged ,Peso corporal ideal ,Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Ideal Body Weight [Medical Subject Headings] ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings] ,Weight Reduction Programs ,Body image ,Female ,medicine.symptom ,peso corporal ideal ,Estils de vida ,doxorrubicina ,body image ,Population ,Imagen corporal ,030209 endocrinology & metabolism ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior [Medical Subject Headings] ,overweight ,Healthy Lifestyle ,Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings] ,business.industry ,índice de masa corporal ,Feeding Behavior ,Dieta mediterránea ,Diet ,Doxorubicin ,Sobrepeso ,Patient Compliance ,Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Image [Medical Subject Headings] ,business ,Food Science - Abstract
Background. Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives. The aim of this study was to assess the association between the adherence to the Mediterranean lifestyle (diet and exercise) and the desired body weight loss in an adult Mediterranean population with overweight. Methods. Cross-sectional analysis in 6355 participants (3268 men; 3087 women) with metabolic syndrome and BMI (Body mass index) between 27.0 and 40.0 kg/m2 (55–75 years old) from the PREDIMED-Plus trial. Desired weight loss was the percentage of weight that participants wished to lose. It was categorized into four cut-offs of this percentage (Q1, European Research Council (ERC) 340918, Recercaixa Grant 2013ACUP00194, Junta de Andalucia PI0458/2013 PS0358/2016 PI0137/2018, Generalitat Valenciana PROMETEO/2017/017, SEMERGEN Grant, European Union (EU) European Cooperation in Science and Technology (COST) CA16112, Balearic Islands Government 35/2011, Balearic Islands Health Research Institute (IDISBA), European Union (EU) CIBEROBN CB06/03 CB12/03 PI13/00673 PI13/00492 PI13/00272 PI13/01123 PI13/00462 PI13/00233 PI13/02184 PI13/00728 PI13/01090 PI13/01056, European Commission Joint Research Centre EAT2BENICE_H2020_SFS2016, "Miguel Servet Type I" program from the ISCIII-Madrid (Spain) CP15/00028, ICREA under the ICREA Academia programme, Fernando Tarongi Bauza PhD Grant, FPU from the Ministry of Science, Innovation and Univesities FPU 18/01703, Spanish government, ISCIII, through the Fondo de Investigacion para la Salud (FIS), Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332
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- 2020
13. Dietary Quality Changes According to the Preceding Maximum Weight: A Longitudinal Analysis in the PREDIMED-Plus Randomized Trial
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Aurora Bueno-Cavanillas, Jose Lopez-Miranda, Miguel Delgado-Rodríguez, Maria del Mar Bibiloni, David Mateos, Helmut Schröder, Emilio Ros, José Carlos Fernández-García, Ramon Estruch, José Lapetra, Andrea Bernabé-Casanova, Andreu Altés-Boronat, Itziar Abete, Dora Romaguera, Lidia Daimiel, Bogdana L. Luca, Carmen Saiz, Ignacio M. Gimenez-Alba, Jesús Vioque, Silvia Moreno García, Ángel M. Alonso-Gómez, Marian Martin-Padillo, Julia Wärnberg, María Ortíz-Ramos, Nerea Becerra-Tomás, Silvia Canudas, Luis Serra-Majem, Cesar I Fernandez-Lazaro, Maria Angeles Zulet, Cristina Bouzas, F. Javier Basterra-Gortari, Maria C Belló-Mora, Pablo Hernández-Alonso, J. Alfredo Martínez, José Manuel Santos-Lozano, Dolores Corella, Carmen Sayón-Orea, Olga Castañer, Rafael M. Micó-Pérez, Xavier Pintó, Maria Dolors Zomeño, Jessica Pérez-López, Jordi Salas-Salvadó, Francisco J. Tinahones, Albert Goday, Sara Castro-Barquero, Miguel Ángel Martínez-González, Josep A. Tur, Antonio Garcia-Rios, and Lucas Tojal-Sierra
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Male ,cumplimiento del paciente ,Mediterranean diet ,humanos ,Overweight ,Diet, Mediterranean ,law.invention ,encuestas sobre dietas ,Clinical trials ,0302 clinical medicine ,Randomized controlled trial ,Behavior Therapy ,Weight loss ,law ,estudios prospectivos ,Weight management ,Medicine ,Longitudinal Studies ,Prospective Studies ,030212 general & internal medicine ,skin and connective tissue diseases ,mediana edad ,anciano ,Nutrition and Dietetics ,sobrepeso ,dieta ,resultado del tratamiento ,Maximum weight ,modelos lineales ,Middle Aged ,Weight Reduction Programs ,Treatment Outcome ,Body image ,Diet quality ,Cardiovascular Diseases ,estilo de vida ,programas de reducción de peso ,Female ,Dieta ,terapia conductista ,dietary pattern ,Diet, Healthy ,pérdida de peso ,medicine.symptom ,maximum weight ,lcsh:Nutrition. Foods and food supply ,body image ,enfermedades cardiovasculares ,Pes corporal ,Dietary pattern ,lcsh:TX341-641 ,030209 endocrinology & metabolism ,Diet Surveys ,Article ,03 medical and health sciences ,Weight Loss ,Humans ,Obesity ,Life Style ,obesidad ,Aged ,General linear model ,business.industry ,PREDIMED-Plus ,Body weight ,Predimed ,Diet ,Linear Models ,Patient Compliance ,estudios longitudinales ,Body-Weight Trajectory ,sense organs ,business ,Assaigs clínics ,Food Science ,Demography - Abstract
One-year dietary quality change according to the preceding maximum weight in a lifestyle intervention program (PREDIMED-Plus trial, 55–75-year-old overweight or obese adults; n = 5695) was assessed. A validated food frequency questionnaire was used to assess dietary intake. A total of 3 groups were made according to the difference between baseline measured weight and lifetime maximum reported weight: (a) participants entering the study at their maximum weight, (b) moderate weight loss maintainers (WLM), and (c) large WLM. Data were analyzed by General Linear Model. All participants improved average lifestyle. Participants entering the study at their maximum weight were the most susceptible to improve significantly their dietary quality, assessed by adherence to Mediterranean diet, DII and both healthful and unhealthful provegetarian patterns. People at maximum weight are the most benefitted in the short term by a weight management program. Long term weight loss efforts may also reduce the effect of a weight management program., European Research Council (ERC) 340918, Official funding agency for biomedical research of the Spanish government, ISCIII, through the Fondo de Investigacion para la Salud (FIS), Junta de Andalucia PI0458/2013 PS0358/2016 PI0137/2018, Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensive sobre la actividad fisica Cohorte PREDIMED-Plus grant, Recercaixa Grant 2013ACUP00194, Generalitat Valenciana PROMETEO/2017/017, SEMERGEN Grant, European Union (EU) European Cooperation in Science and Technology (COST) CA16112, Balearic Islands Government 35/2011, Balearic Islands Health Research Institute (IDISBA), European Union (EU) CIBEROBN CB06/03 CB12/03 PI13/00673 PI13/00492 PI13/00272 PI13/01123 PI13/00462 PI13/00233 PI13/02184 PI13/00728 PI13/01090 PI13/01056 PI14/01722 PI14/00636 PI14/00618 PI14/00696 PI14/01206 PI14/01919 PI14/00853 PI14/01374 PI14/00972 PI14/00728, European Commission European Commission Joint Research Centre EAT2BENICE_H2020_SFS2016, Fernando Tarongi Bauza Grant, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI14/01471, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332
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- 2020
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14. ADHERENCE TO TREATMENT OF TYPE 2 DIABETES MELLITUS: A SYSTEMATIC REVIEW OF RANDOMIZED CLINICAL ESSAYS.
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Timm, Márcia, Soares Rodrigues, Maria Cristina, and Bertonha Machado, Valéria
- Abstract
Copyright of Journal of Nursing UFPE / Revista de Enfermagem UFPE is the property of Revista de Enfermagem UFPE and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2013
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15. Treatment outcomes for human African Trypanosomiasis in the Democratic Republic of the Congo: analysis of routine program data from the world's largest sleeping sickness control program.
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Hasker, E., Mpanya, A., Makabuza, J., Mbo, F., Lumbala, C., Kumpel, J., Claeys, Y., Kande, V., Ravinetto, R., Menten, J., Lutumba, P., and Boelaert, M.
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TREATMENT of African trypanosomiasis , *TREATMENT effectiveness , *ELECTRONIC health records , *PATIENT compliance , *FOLLOW-up studies (Medicine) , *TUBERCULOSIS prevention - Abstract
Objective To enable the human African trypanosomiasis (HAT) control program of the Democratic Republic of the Congo to generate data on treatment outcomes, an electronic database was developed. The database was piloted in two provinces, Bandundu and Kasai Oriental. In this study, we analysed routine data from the two provinces for the period 2006-2008. Methods Data were extracted from case declaration cards and monthly reports available at national and provincial HAT coordination units and entered into the database. Results Data were retrieved for 15 086 of 15 741 cases reported in the two provinces for the period (96%). Compliance with post-treatment follow-up was very poor in both provinces; only 25% had undergone at least one post-treatment follow-up examination, <1% had undergone the required four follow-up examinations. Relapse rates among those presenting for follow-up were high in Kasai (18%) but low in Bandundu (0.3%). Conclusions High relapse rates in Kasai and poor compliance with post-treatment follow-up in both provinces are important problems that the HAT control program urgently needs to address. Moreover, in analogy to tuberculosis control programs, HAT control programs need to adopt a recording and reporting routine that includes reporting on treatment outcomes. [ABSTRACT FROM AUTHOR]
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- 2012
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16. The effect of patient satisfaction with pharmacist consultation on medication adherence: an instrumental variable approach.
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Ning Yan GU, Yunwei GAI, and HAY, Joel W.
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PATIENT satisfaction ,PATIENT-professional relations ,HEALTH attitudes ,PHARMACIST-patient relationships ,PATIENT compliance ,PHARMACY ,PHARMACISTS - Abstract
Copyright of Pharmacy Practice (1886-3655) is the property of Centro de Investigaciones y Publicaciones Farmaceuticas S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2008
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17. Adherence to treatment: what is done in Sweden? Practice, education and research.
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SÖDERGÅRD, Björn
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PHARMACISTS ,PATIENT compliance ,PATIENT participation ,PHARMACIST-patient relationships ,MANAGEMENT science - Abstract
Copyright of Pharmacy Practice (1886-3655) is the property of Centro de Investigaciones y Publicaciones Farmaceuticas S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2008
18. Developing a generic, individualised adherence programme for chronic medication users.
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HERBORG, Hanne, HAUGBØLLE, Lotte S., SØRENSEN, Lene, ROSSING, Charlotte, and DAM, Pernille
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DRUG utilization ,GENERIC drugs ,DRUGS ,GENERIC products ,COUNSELING ,MEDICINE - Abstract
Copyright of Pharmacy Practice (1886-3655) is the property of Centro de Investigaciones y Publicaciones Farmaceuticas S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2008
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19. Automated dose dispensing in Danish primary health care - a technology under construction.
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Herborg, Hanne, Haugbølle, Lotte S., and Lee, Anne
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PATIENT compliance ,AUTOMATION ,DRUG delivery systems ,QUALITATIVE research ,PATIENT participation - Abstract
Copyright of Pharmacy Practice (1886-3655) is the property of Centro de Investigaciones y Publicaciones Farmaceuticas S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2008
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20. Investigation of barriers to clinical practice guideline-recommended pharmacotherapy in the treatment of COPD.
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Price, Lea, Billups, Sarah J., Rice, Melissa A., and Hartsfield, Cynthia
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OBSTRUCTIVE lung diseases ,DRUG therapy ,SPIROMETRY ,MEDICAL records ,DRUG administration ,DRUG side effects - Abstract
Copyright of Pharmacy Practice (1886-3655) is the property of Centro de Investigaciones y Publicaciones Farmaceuticas S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2007
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21. Prevalence of healthy lifestyles against cancer in Spanish women
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Adela Castelló, Carmen Vidal, Carmen Sánchez-Contador, Carmen Santamariña, Carmen Pedraz-Pingarrón, Nuria Aragonés, Dolores Salas, Nieves Ascunce, Marina Pollán, Virginia Lope, María José Toribio, Beatriz Pérez-Gómez, Pilar Moreo, Ministerio de Sanidad y Política Social (España), Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), and Federación Española de Cáncer de Mama
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0301 basic medicine ,consumo de alcohol ,cumplimiento del paciente ,humanos ,Breastfeeding ,lcsh:Medicine ,ejercicio físico ,Cancer prevention ,Body Mass Index ,Breast cancer screening ,0302 clinical medicine ,Risk Factors ,Neoplasms ,Prevalence ,Medicine ,Mass Screening ,lcsh:Science ,Early Detection of Cancer ,mediana edad ,neoplasias ,education.field_of_study ,anciano ,Multidisciplinary ,medicine.diagnostic_test ,dieta ,Incidence (epidemiology) ,Smoking ,prevalencia ,Middle Aged ,autoinforme ,detección precoz del cáncer ,Transgender hormone therapy ,Female ,Alcohol Drinking ,Population ,cribado sistemático ,Article ,03 medical and health sciences ,Cancer epidemiology ,Breast cancer ,Environmental health ,ingesta energética ,Humans ,factores de riesgo ,Healthy Lifestyle ,education ,Exercise ,Aged ,business.industry ,lcsh:R ,Body Weight ,índice de masa corporal ,peso corporal ,hábito de fumar ,medicine.disease ,Diet ,030104 developmental biology ,Cross-Sectional Studies ,Spain ,Patient Compliance ,lcsh:Q ,Self Report ,business ,Energy Intake ,Breast feeding ,030217 neurology & neurosurgery ,estudios transversales - Abstract
Modifying behavior towards healthier lifestyles could prevent a significant number of malignant tumors. We evaluated the prevalence of healthy habits against cancer in Spanish women free of this disease, taking as a reference the recommendations for cancer prevention included in the European Code Against Cancer (ECAC), and we explored the characteristics associated with it. Our population comprised 3,584 women recruited in a population-based cross-sectional study carried out in 7 breast cancer screening programs. Information was directly surveyed and used to calculate a score based on ECAC recommendations referred to bodyweight, physical activity, diet, breastfeeding, tobacco, alcohol and hormone replacement therapy use. The degree of adherence was estimated with a score that evaluated null (0 points), partial (0.5 points) and full adherence (1 point) of each specific recommendation. Associations were explored using binary and ordinal logistic regression models. The median score was 5.7 out of 9 points. Recommendations with lower adherence were those related to intake of red/processed meat and foods high in salt (23% of total adherence), physical activity (24%) and body weight (29%), and recommendations with greater adherence where those related to hormone replacement therapy use (91%), vegetable intake (84%), alcohol (83%) and tobacco (61%). Overall adherence was better among older women, parous women, and in those living in rural areas, and worse among women with higher caloric intake. These recommendations should be evaluated periodically. Screening programs can be an appropriate place to disseminate this information., This study was supported by the Spanish Public Health Research Fund (FIS PI060386 & PS09/0790); by the Spanish Ministry of Health, Social Policy and Equality (EC11-273), by the Carlos III Institute of Health (ISCIII) (AESI PI15CIII/00013); by the Spanish Ministry of Economy and Competitiveness, Juan de la Cierva de Incorporacion grant (IJCI-2014-20900); by the EPY 1306/06 Collaboration Agreement between Astra-Zeneca and the Carlos III Institute of Health; and a grant from the Spanish Federation of Breast Cancer patients (FECMA EPY 1169/10). The authors wish to thank the participants in the DDM-Spain study for their contribution to breast cancer research.
- Published
- 2019
22. Association of adherence to the mediterranean diet with urinary factors favoring renal lithiasis: cross-sectional study of overweight individuals with metabolic síndrome
- Author
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Jordi Salas-Salvadó, Olga Castañer, Rafael M. Prieto, Dora Romaguera, Felix Grases, Pilar Sanchis, Miquel Fiol, Margalida Morey, Miguel Ángel Martínez-González, and Adrian Rodriguez
- Subjects
Male ,cumplimiento del paciente ,Time Factors ,Mediterranean diet ,Cross-sectional study ,humanos ,030232 urology & nephrology ,Urinary crystallization risk ,Overweight ,Diet, Mediterranean ,0302 clinical medicine ,Urolithiasis ,Recurrence ,Risk Factors ,evaluación de riesgos ,Prevalence ,030212 general & internal medicine ,10. No inequality ,mediana edad ,Randomized Controlled Trials as Topic ,2. Zero hunger ,Metabolic Syndrome ,anciano ,Nutrition and Dietetics ,sobrepeso ,dieta ,European research ,ensayos clínicos controlados aleatorizados como asunto ,resultado del tratamiento ,prevalencia ,Renal lithiasis ,Middle Aged ,3. Good health ,Treatment Outcome ,Female ,medicine.symptom ,Diet, Healthy ,lcsh:Nutrition. Foods and food supply ,Urinary system ,European Regional Development Fund ,lcsh:TX341-641 ,Risk Assessment ,Article ,03 medical and health sciences ,factores de tiempo ,Ciencias de la Salud::Medicina preventiva [Materias Investigacion] ,medicine ,factores de riesgo ,Humans ,Aged ,conducta alimentaria ,business.industry ,urolitiasis ,Feeding Behavior ,Protective Factors ,medicine.disease ,Diet ,Cross-Sectional Studies ,Spain ,Patient Compliance ,Metabolic syndrome ,business ,recurrencia ,Biomarkers ,Food Science ,Demography ,estudios transversales - Abstract
Our purpose was to study the relationship of adherence to the Mediterranean diet (MedDiet) with urinary factors that favor the formation of renal calcium and uric acid stones in overweight and obese participants who had metabolic syndrome. This cross-sectional study examined 267 participants. A well-known MedDiet score (range 0&ndash, 9) was calculated for each patient, and patients were then categorized has having low (&le, 3), medium (4&ndash, 5), or high (&ge, 6) adherence to the MedDiet. Baseline characteristics and urinary parameters were also analyzed. High calcium salt urinary crystallization risk (CaUCR) and high uric acid urinary crystallization risk (UrUCR) were calculated from urinary parameters using pre-defined criteria. More than half of patients with MedDiet scores &le, 3 had high UrUCR (55.4%) and high CaUCR (53.8%). In contrast, fewer patients with high adherence (&ge, 6) to the MedDiet had high UrUCR (41.2%) and high CaUCR (29.4%). Relative to those with low adherence, individuals with high adherence had a prevalence ratio (PR) of 0.77 for a high UrUCR (95% CI: 0.46&ndash, 1.12, p for trend: 0.069) and a PR of 0.51 for a high CaUCR (95% CI: 0.26&ndash, 0.87, p for trend: 0.012) after adjusting for age, sex, body mass index, type 2 diabetes, and total energy intake. Our findings indicate that greater adherence to the MedDiet was associated with a reduced CaUCR and a reduced UrUCR. This suggests that adequate dietary management using the MedDiet patterns may prevent or reduce the incidence and recurrence of calcium salt and uric acid renal stones.
- Published
- 2019
23. Falta de adherencia al tratamiento fisioterapéutico en pacientes con trastornos musculoesqueléticos en una clínica docente en Lima, Perú
- Author
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D. Coello-Talavera, P. Mayta-Tristán, and N. Rojas-Motta
- Subjects
030506 rehabilitation ,Servicios integrados de asistencia a la enseñanza ,Teaching care integration services ,Patient compliance ,Physical Therapy, Sports Therapy and Rehabilitation ,Treatment ,03 medical and health sciences ,0302 clinical medicine ,Cumplimiento del paciente ,Tratamiento ,030212 general & internal medicine ,0305 other medical science ,Physical therapy ,Fisioterapia - Abstract
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. Objetivo Conocer la incidencia y los factores de riesgo asociados a la falta de adherencia al tratamiento fisioterapéutico en pacientes con dolor y trastornos músculo esqueléticos que asisten a una clínica docente en Lima, Perú. Materiales y métodos Estudio de cohorte retrospectivo, incluyó a todos los pacientes nuevos atendidos por dolor y trastornos musculoesqueléticos en el periodo 2012-2014. Se midieron la falta de adherencia (asistencia menor a las 8 sesiones indicadas) y los factores demográficos. Se calcularon los riesgos relativos crudos y ajustados (RRa). Resultados Se incluyó a 549 pacientes, el 68,3% fueron mujeres, el 37,2% tuvo 60 o más años, las lesiones más frecuentes se ubicaron en el miembro inferior (34,2%) y el dorso lumbar (24,6%). Se encontró una incidencia de falta de adherencia de 56,4% (IC del 95%, 52,2 a 60,7%) y estuvo asociada a residir lejos de la clínica (RRa: 1,34; IC del 95%, 1,16 a 1,57) y tener menos de 40 años (RRa: 1,27; IC del 95%, 1,04 a 1,54). Conclusión Existe una alta incidencia de falta de adherencia al tratamiento fisioterapéutico relacionado con la distancia y la edad de los pacientes, por lo que se deben buscar estrategias para aumentar la adherencia. Revisión por pares
- Published
- 2016
24. Treatment adherence in patients more than 65 years who experience early readmissions
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Vicente-Sánchez, Sergio, Olmos-Jiménez, Raquel, Ramírez-Roig, Cristina, García-Sánchez, María José, Valderrey-Pulido, Manuel, and de la Rubia-Nieto, Amelia
- Subjects
Aging ,Cumplimiento del paciente ,Patient adherence ,Polypharmacy ,Envejecimiento ,Medication adherence ,Reingresos ,Adherencia a la medicación ,Readmission ,Polimedicación - Abstract
Objective: To analyse the rate of therapeutic nonadherence in patients who experience early readmissions, and identify the factors associated with nonadherence. Methods: An observational descriptive 3-month study (March-May 2014), which included all patients more than 65 years who were readmitted between 3 to 30 days following the last hospital discharge. Exclusion criteria: programmed re-admissions and readmissions to the Intensive Care Unit. Variables included in the study: age, sex, medical service, major diagnostic category, polypharmacy, number of days since the last hospital discharge, and hypertension and diabetes. Therapeutic adherence and difficulty in taking medication were assessed using the Morisky-Green test and the Haynes-Sackett test, respectively. A descriptive analysis of the variables was conducted, showing they were associated with therapeutic adherence. Statistically significant variables were included in a multivariate logistic regression model. Results: In total, 57% of the patients were nonadherent to pharmacological treatment; 23% had difficulty taking their medication; 86% had comorbidities (hypertension and diabetes); 79% had a caregiver; and 86% were polymedicated (≥ 5 medications). There was an association between lack of adherence and difficulty in taking medications (P = 0.021), polypharmacy (P = 0.002), and diabetes mellitus (P = 0.018). Conclusions: Polymedication, diabetes mellitus, and difficulty in taking medication were shown to be prognostic factors of lack of adherence to treatment in patients more than 65 years. Resumen Objetivo: Analizar la frecuencia del incumplimiento terapéutico en pacientes que sufren reingresos hospitalarios precoces e identificar los factores asociados al mismo. Método: Estudio observacional descriptivo de tres meses de duración (marzo-mayo de 2014). Se incluyeron todos los pacientes mayores de 65 años que reingresaron en los 3-30 días siguientes al alta hospitalaria. Fueron excluidos los reingresos programados y los reingresos en la Unidad de Cuidados Intensivos. Las variables recogidas fueron: edad, sexo, servicio médico, categoría diagnóstica mayor, polimedicación, número de días desde el alta, presencia de hipertensión y/o diabetes. Se evaluó el cumplimiento terapéutico y la dificultad en la administración de medicación mediante el test de Morisky-Green y el test de Haynes-Sackett, respectivamente. Se realizó un análisis descriptivo de las variables y se relacionaron estas con la adherencia terapéutica. Las variables con significación estadística se incluyeron en un modelo de regresión logística multivariante. Resultados: El 57% de los pacientes presentaron falta de adherencia al tratamiento farmacológico. El 23% presentaba dificultad en la administración de la medicación. Un 86% presentaba comorbilidades (hipertensión y/o diabetes) y el 79% tenía cuidador. El 86% de los pacientes estaban polimedicados (≥ 5 fármacos). Existe relación entre la falta de adherencia y la dificultad en la administración de los medicamentos (p = 0,021), la polimedicación (p = 0,002) y la presencia de diabetes mellitus (p=0,018). Conclusiones: La polimedicación, la presencia de diabetes mellitus y la existencia de dificultad en la administración de la medicación se evidencian como factores pronósticos de la falta de adherencia al tratamiento en pacientes mayores de 65 años.
- Published
- 2018
25. Methods for measuring adherence to oral disease-modifying drugs in rheumatoid arthritis and factors associated with low adherence to pharmacological treatment
- Author
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Claudia Mora Karam, Jenny Rincón, Angélica Téllez, Diego Alejandro Jaimes Fernández, Julio César García Casallas, Daniel G. Fernández-Ávila, and Adriana Beltrán
- Subjects
030203 arthritis & rheumatology ,Medicamentos antirreumáticos modificadores de la enfermedad ,business.industry ,Adherencia a los medicamentos ,Patient compliance ,Disease-modifying antirheumatic drug ,Artritis reumatoide ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Cumplimiento del paciente ,Medicine ,030212 general & internal medicine ,Rheumatoid arthritis ,business ,Medication adherence ,Humanities - Abstract
RESUMEN Objetivos: Revisar definiciones, factores asociados a adherencia, métodos para medición y determinación de adherencia a medicamentos modificadores de la enfermedad orales en artritis reumatoide. Métodos: Se realizó una búsqueda de la literatura en las bases de datos de Pubmed hasta diciembre de 2017 mediante términos MeSH (((«Arthritis, Rheumatoid» [Mesh] AND «Medication Adherence» [Mesh]) OR «Patient Compliance» [Mesh]) AND «Antirheumatic Agents» [Mesh]) de artículos que estuvieran en idioma espafñol o inglés e incluyeran solo población adulta. Resultados: De un total de 387 artículos encontrados, 43 se incluyeron para la revisión general, con información sobre definiciones de adherencia, cumplimiento, concordancia y persistencia, componentes, clasificación y dimensiones, factores de riesgo relacionados con la no adherencia al tratamiento, descripción de los métodos de medición. Solo 9 artículos midieron adherencia e incluyeron información sobre factores relacionados con adherencia a medicamentos orales en artritis reumatoide. Conclusiones: La adherencia al tratamiento farmacológico en artritis reumatoide es subóptima y se relaciona con menor efectividad en el control de la actividad inflamatoria. Los principales factores relacionados con baja adherencia incluyen problemas de acceso y disponibilidad del medicamento, mayor actividad y duración de la enfermedad, polifarmacia, uso de medicamentos por periodos prolongados, bajo estrato socioeconómico, etnia, reacciones adversas por medicamentos, percepción de inefectividad de la medicación y enfermedades concomitantes. Es necesario incorporar de forma sistemática la medición de adherencia farmacológica dentro de la práctica clínica rutinaria y la identificación de los factores de riesgo más frecuentes asociados a una baja adherencia con el fin de diseñar estrategias encaminadas a mejorar la adherencia de los pacientes y lograr mejores desenlaces clínicos. ABSTRACT Objectives: To review the definitions, associated factors, as well as the methods for the measurement and determination of adherence to oral disease modifying drugs in rheumatoid arthritis. Methods: A search of the literature was carried out in the PUBMED databases up to December 2017 using MeSH terms: ((("Arthritis, Rheumatoid" [Mesh] AND "Medication Adherence" [Mesh]) OR "Patient Compliance" [Mesh]) AND "Antirheumatic Agents" [Mesh]). Only articles that included an adult population and were in Spanish or English were reviewed. Results: From the 387 articles found, 43 were included for general review (definitions of adherence, compliance, concordance and persistence, components, classification and dimensions of adherence, risk factors related to non-adherence, description of direct and indirect methods for measuring adherence). Only 9 articles measured adherence and included information about risk factors related to non-adherence to oral treatment in rheumatoid arthritis. Conclusions: The adherence to pharmacological treatment in rheumatoid arthritis is sub-optimal and is associated with less effectiveness in the control of inflammatory activity. The main factors related to low adherence include problems of drug access and availability, increased activity and duration of the disease, polypharmacy, use of medications for prolonged periods, socioeconomic stratum, ethnicity, adverse drug reactions, perception of ineffectiveness of the medication, and concomitant diseases. It is necessary to incorporate the systematic measurement of pharmacological adherence within clinical practice. It is also important to identify the most frequent risk factors associated with low adherence, in order to design strategies aimed at improving patient adherence and achieve better clinical outcomes.
- Published
- 2018
26. Efectividad de la Distracción Musical Sobre la Ansiedad Dental y Adherencia a Tratamiento en Niños de 6 Años: Ensayo Clínico Aleatorizado
- Author
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Rojas-Alcayaga, Gonzalo A., Alfaro, Karen, Ríos-Erazo, Matías, Herrera, Andrea C., and Barahona, Pilar
- Subjects
cuidado dental para niños ,stomatognathic diseases ,dental care for children ,ansiedad dental ,stomatognathic system ,musical distraction ,dental anxiety ,Distracción musical ,patient compliance ,cumplimiento del paciente - Abstract
Dental anxiety can be a barrier to following healthy behaviours. Musical distraction is an effective strategy to reduce dental anxiety and improve treatment adherence. The aim was to determine the effect of musical distraction on dental anxiety and treatment adherence in 6-year-old children. Multicenter randomized control trial with 176 children who were allocated into two parallel groups. One group received usual dental care (N 88), and the other was exposed to musical distraction during usual dental care (N 88). The primary outcome was dental anxiety and secondary was oral health status and oral health care behaviours. Both were assessed at baseline, discharged and six-month follow-up. Mid/high dental anxiety was exhibited by 16.1 % of the children. Musical distraction had no effect on dental anxiety levels in the experimental compared with the control group at any of the time points assessed. The size effect was 0.35 and 0.15 (Cliff’s Delta) for baseline-discharge and 0.57 and 0.35 for baseline-six month. Only 47.7 % of the sample attended at 6-month follow-up. Dental anxiety is not prevalent in the sample and is not beneficially reduced by musical distraction. The educational actions of the dental care programme are not sufficient to attain permanent long-term changes in oral health behaviour. RESUMEN: La ansiedad dental puede ser una barrera para seguir conductas saludables. La distracción musical es una estrategia efectiva para reducir la ansiedad dental y mejorar la adherencia al tratamiento. El objetivo fue determinar el efecto de la distracción musical sobre la ansiedad dental y la adherencia al tratamiento en niños de 6 años. Ensayo multicéntrico de control aleatorizado con 176 niños asignados a dos grupos paralelos. Un grupo recibió atención dental habitual (n 88) y el otro estuvo expuesto a distracción musical durante el cuidado dental habitual (N 88). El resultado primario fue la ansiedad dental y secundaria fue el estado de salud oral y las conductas de salud oral. Ambos fueron evaluados al inicio, dados de alta y seguidos durante seis meses. La ansiedad dental media / alta fue exhibida por 16,1 % de los niños. La distracción musical no tuvo ningún efecto sobre los niveles de ansiedad dental en el grupo experimental en comparación con el grupo control en ninguno de los momentos evaluados. El efecto del tamaño fue 0,35 y 0,15 (Cliff's Delta) para el inicio y el alta y 0,57 y 0,35 para el inicio y los seis meses de seguimiento. Solo el 47,7 % de la muestra asistió a los 6 meses de seguimiento. La ansiedad dental no prevalece en la muestra y no se ve beneficiada por la distracción musical. Las acciones educativas del programa de atención dental no son suficientes para lograr cambios permanentes a largo plazo en el comportamiento de salud oral.
- Published
- 2018
27. Dietary intake in population with metabolic syndrome: is the prevalence of inadequate intake influenced by geographical area? cross-sectional analysis from PREDIMED-Plus Study
- Author
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Estefanía Toledo, Aurora Bueno-Cavanillas, Clotilde Vázquez, Andrés Díaz-López, Juan Manuel Zazo, Alfredo Gea, Josep A. Tur, M. Dolors Zomeño, Miguel A. Muñoz, Antonio Garcia-Rios, Miguel Ruiz-Canela, Lluis Serra-Majem, J. Alfredo Martínez, Montse Fitó, Lidia Daimiel, Pilar Matía, Jordi Salas-Salvadó, Emilio Ros, Francisco J. Tinahones, Dora Romaguera, Manoli Garcia-de-la-Hera, Laura García-Molina, Josep Vidal, Rebeca Fernández-Carrión, José J. Gaforio, Miguel Ángel Martínez-González, Dolores Corella, Antoni Colom, Javier Díez-Espino, Josep Basora, Ramon Estruch, Naomi Cano-Ibáñez, José Lapetra, F. Javier Barón-López, Xavier Pintó, Naiara Cubelos-Fernández, and Angel M Alonso Gómez
- Subjects
0301 basic medicine ,Male ,Síndrome metabòlica ,cumplimiento del paciente ,Cross-sectional study ,humanos ,ejercicio físico ,Overweight ,Diet, Mediterranean ,Recommended Dietary Allowances ,geografía ,Nutrient ,Clinical trials ,Surveys and Questionnaires ,Food choice ,Prevalence ,Medicine ,Micronutrients ,mediana edad ,Dietoteràpia ,Randomized Controlled Trials as Topic ,2. Zero hunger ,education.field_of_study ,anciano ,Nutrition and Dietetics ,sobrepeso ,Geography ,dieta ,ensayos clínicos controlados aleatorizados como asunto ,prevalencia ,PREDIMED-Plus study ,Middle Aged ,Metabolic syndrome ,3. Good health ,estado nutricional ,Dietary Reference Intake ,Place of residence ,Female ,medicine.symptom ,evaluación nutricional ,cantidad dietética recomendada ,geographical area ,lcsh:Nutrition. Foods and food supply ,nutrient adequacy ,Population ,Nutritional Status ,lcsh:TX341-641 ,metabolic syndrome ,Article ,03 medical and health sciences ,Environmental health ,Humans ,place of residence ,cardiovascular diseases ,Obesity ,education ,obesidad ,Exercise ,Aged ,Geographical area ,030109 nutrition & dietetics ,Nutrient adequacy ,business.industry ,Dietary intake ,Diet therapy ,micronutrientes ,medicine.disease ,Diet ,Cross-Sectional Studies ,Nutrition Assessment ,Spain ,Patient Compliance ,business ,dietary intake ,Food Science ,Assaigs clínics ,estudios transversales - Abstract
Inadequate diet influences chronic diseases such as cardiovascular disease (CVD), the leading cause of death in Spain. CVD figures vary from one geographical region to another, this could be associated with different food choices. Our aim was to analyse the influence of geographical area on nutrient intakes among the Spanish adult population with Metabolic Syndrome (MetS). We analysed cross-sectional baseline data from the PREDIMED-Plus study: 6646 Spanish adults, aged 55&ndash, 75 years, with overweight/obesity and MetS in four geographical areas. A validated 143-item Food Frequency Questionnaire (FFQ) was used to assess energy and nutrient intakes. The prevalence of inadequate nutrient intake was estimated according to Dietary Reference Intakes (DRIs). Multivariable-adjusted logistic regression was used to assess the relationship between geographical area (North, Central, East and South areas) and inadequate nutrient intake. People in the North area consumed significantly lower amounts of vegetables and fish but more sugar and alcohol (p <, 0.001) than other areas. Dietary fibre, vitamin A, E, calcium and magnesium intakes were all lower among men of North area than in the other areas (p <, 0.001). Sex (women), non-smoker and physical activity were also associated to adequate nutrient intake. Geographical area influences nutrient intakes. Its effect on dietary quality should be taken into account when planning food policies.
- Published
- 2018
28. Assessing medication adherence in inflammatory bowel diseases: a comparison between a self-administered scale and a pharmacy refill index
- Author
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de-Castro, María-Luisa, Sanromán, Luciano, Martín, Alicia, Figueira, Montserrat, Martínez, Noemí, Hernández, Vicent, del-Campo, Víctor, Pineda, Juan-Ramón, Martínez-Cadilla, Jesús, Pereira, Santos, and Rodríguez-Prada, Ignacio
- Subjects
Reproducibility of results ,Encuestas y cuestionarios ,Enfermedad inflamatoria intestinal ,Cumplimiento del paciente ,Reproducibilidad de los resultados ,Patient compliance ,Pharmacy ,Surveys and questionnaires ,Farmacia ,Medication adherence ,Inflammatory bowel disease ,Adhesión terapéutica - Abstract
Background: Medication non-adherence in inflammatory bowel disease (IBD) has a negative impact on disease outcome. Different tools have been proposed to assess non-adherence. We aimed to compare a self-administered scale and a pharmacy refill index as a reliable measure of medication adherence and to determine what factors are related to adherence. Methods: Consecutive non-active IBD outpatients were asked to fill in the self-reported Morisky Medication Adherence Scale (MMAS-8) and the Beliefs about Medication Questionnaire (BMQ). Pharmacy refill data were reviewed from the previous three or six months and the medication possession ratio (MPR) was calculated. Non-adherence was defined as MMAS-8 scores < 6 or MPR < 0.8. Results: Two-hundred and three patients were enrolled (60% ulcerative colitis, 40% Crohn's disease); 51% were men, and the mean age was 46.3 (14) years. Seventy-four per cent of patients were on monotherapy and 26% on combination therapy; altogether, 65% received mesalazine, 46% thiopurines and 16% anti-tumor necrosis factor alfa. Non-adherence rate assessed by MPR was 37% and 22.4% by MMAS-8. Receiver operator curve analysis using a MMAS-8 cut-off of six gave an area under the curve of 0.6 (95% CI 0.5-0.7), p = 0.001. This score had an 85% sensitivity and 34% specificity to predict medication non-adherence, with negative and positive predictive values of 57% and 70% respectively. High scores in the BMQ potential for harm of medication were significantly associated with MPR non-adherence (p = 0.01). Conclusion: The accuracy of MMAS-8 to identify medication non-adherence in inactive IBD outpatients in our setting is poor due to a low specificity and a negative predictive value. Psychosocial factors such as beliefs about medication seem to be related to IBD non-adherence. Introducción: la falta de adhesión terapéutica en la enfermedad inflamatoria intestinal (EII) tiene un impacto negativo en el control de la enfermedad. Existen diferentes herramientas para evaluar la falta de adhesión. Nuestro objetivo fue comparar una escala de autoevaluación con un índice de posesión de medicación, e identificar los factores relacionados con falta de adhesión. Métodos: solicitamos a pacientes ambulatorios con EII inactiva que rellenasen los cuestionarios de adhesión MMAS-8 y de opiniones sobre medicación BMQ. Revisamos los registros de dispensación farmacéutica en los 3-6 meses anteriores calculando el índice de posesión de medicación (MPR). Consideramos no adhesión terapéutica valores de MMAS-8 < 6 y MPR < 0,8, respectivamente. Resultados: incluimos a 203 pacientes (60% colitis ulcerosa, 40% enfermedad de Crohn), 51% varones, edad 46,3 (14) años. Un 74% empleaba monoterapia y un 26%, terapia combinada; el 65% recibía mesalazina, el 46% tiopurinas y el 16% fármacos anti-TNF. La no adhesión fue 37% evaluada con MPR y 22,4% con MMAS-8. El área bajo la curva ROC del valor 6 de MMAS-8 fue 0,6 (IC 95%: 0,5-0,7, p = 0,001). Esta puntuación mostró una sensibilidad del 85% y una especificidad del 34% para predecir no adhesión terapéutica, con valores predictivos negativos y positivos del 57 y 70% respectivamente. Las puntuaciones altas en la subescala de daño del cuestionario BMQ se asociaron a no adhesión en MPR (p = 0,01). Conclusión: la precisión de MMAS-8 para identificar falta de adhesión en pacientes con EII inactiva en nuestro entorno es pobre dada su baja especificidad y valor predictivo negativo. Las opiniones sobre la medicación parecen estar relacionadas con la adhesión terapéutica en EII.
- Published
- 2017
29. Ten-Year Trends (1999–2010) of Adherence to the Mediterranean Diet among the Balearic Islands’ Adult Population
- Author
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Mónica González, Antoni Pons, Josep A. Tur, Isabel Llompart, Alicia Julibert, and Maria del Mar Bibiloni
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Male ,0301 basic medicine ,cumplimiento del paciente ,Mediterranean diet ,humanos ,Adult population ,ejercicio físico ,government.political_district ,Diet, Mediterranean ,Environmental protection ,Surveys and Questionnaires ,adults ,Medicine ,recuerdo mental ,Mediterranean region ,mediana edad ,anciano ,Balearic islands ,Nutrition and Dietetics ,encuestas de nutrición ,dieta ,Smoking ,Age Factors ,adulto ,Middle Aged ,Place of birth ,Dietary pattern ,Nutrition Surveys ,nutrition survey ,Mediterranean dietary pattern ,Balearic Islands ,Lifestyle factors ,Quartile ,estrés oxidativo ,estilo de vida ,Female ,lcsh:Nutrition. Foods and food supply ,Adult ,factores socioeconómicos ,lcsh:TX341-641 ,Article ,03 medical and health sciences ,Sex Factors ,inflamación ,parasitic diseases ,Humans ,Obesity ,obesidad ,Exercise ,Life Style ,Aged ,Inflammation ,030109 nutrition & dietetics ,business.industry ,hábito de fumar ,Physical activity level ,Diet ,Oxidative Stress ,Cross-Sectional Studies ,Socioeconomic Factors ,Spain ,Mental Recall ,government ,Patient Compliance ,business ,estudios transversales ,Food Science ,Demography - Abstract
The aim of this work was to assess ten-year trends (1999-2010) of adherence to the Mediterranean dietary pattern (MDP) among the Balearic Islands' adult population. Two independent cross-sectional dietary surveys (1999-2000, n = 1200 and 2009-2010 n = 1388, including participants aged 16-65 years) were carried out in the Balearic Islands, Spain. Dietary habits were assessed by means of two 24 h diet recalls and a validated semi-quantitative food-frequency questionnaire that covers 145 food items. Adherence to the MDP was defined according to a score constructed considering the consumption of nine MDP characteristic components: high monounsaturated fatty acids: saturated fatty acids (MUFA:SFA) ratio, moderate ethanol consumption, high legumes, cereals and roots, fruits, vegetables, and fish consumption, and low consumption of meat and milk. Socio-economic status, education level, lifestyle factors and health status were also assessed. Adherence to the MDP was 43.1% (SD 5.8) in 1999-2000 and 44.6% (SD 8.3) in 2009-2010. Higher age was directly associated with higher adherence to the MDP, and this association was stronger in males than in females. Young generations and smokers showed the lowest adherence to MDP, whereas people with higher educational and socio-economic level, and who were physically active showed the highest adherence. According to the place of birth, the increase in the percentage of the adherence to the MDP was observed to be smaller among the Balearic Island's natives than among people born abroad. In 2009-2010, individuals in the MDP's fourth quartile were more likely to be older (aged 46-65 years), and were less likely to have a low occupational level, to have a light physical activity level and to be smoker than in 1999-2000. The adherence to the MDP has been stabilized and slightly recovered among the Balearic Islands' adult population in the last decade., Instituto de Salud Carlos III (Project PI14/00636, Red Predimed-RETIC RD06/0045/1004, and CIBEROBN CB12/03/30038), EU-COST Action CA16112, Grant of support to research groups No. 35/2011 (Balearic Islands Gov.) and EU-FEDER funds. The funding sponsors had no role in the design of the study, in the collection, analyses, or interpretation of the data; in the writing of the manuscript, and in the decision to publish the results.
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- 2017
30. É-Saúde. Servicio online a pacientes. ACCESO DELEGADO
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García Tenorio, Paula and Farjas Abadía, Pilar
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Patient Access to Records ,cumplimiento del paciente ,É-Saúde ,Patients ,acceso del paciente a su historia clínica ,pacientes ,TICs ,Patient Compliance ,Acceso Delegado ,aplicaciones en aparatos electrónicos portátiles ,Mobile Applications - Abstract
É-Saúde es una plataforma tecnológica de servicios online que proporciona herramientas digitales interactivas de comunicación desde cualquier dispositivo conectado a internet como modo de gestión de la información personal de salud entre el paciente y el Servicio Autonómico de Salud. El acceso por parte de terceras personas a la información y servicios que el Servicio Gallego de Salud y la Consellería de Sanidade ponen a disposición de la ciudadanía a través de É-Saúde, se denomina ACCESO DELEGADO. Comunicación - póster presentada en: XXXV Congreso Sociedad Española de Calidad Asistencial (SECA). XIX Jornadas Societat Catalana de Qualitat Assitencial (SCQA). Adecuación y eficiencia: "menos es más", celebrado en Tarragona del 18 al 20 de octubre de 2017.
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- 2017
31. The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery
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Mònica Bulló, Lluis Serra-Majem, Miguel Fiol, Jordi Salas-Salvadó, Estefanía Toledo, Miguel Ángel Martínez-González, José V. Sorlí, Ernest Vinyoles, Fernando Arós, Gianfranco Ciufo, María P. Portillo, Montse Fitó, José Lapetra, Xavier Pintó, Aleix Sala-Vila, Dolores Corella, Emilio Ros, Alfredo García-Layana, Enrique Gómez-Gracia, Ramon Estruch, Alimentació, Nutrició, Creixement i Salut Mental, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Universitat de Barcelona, [Garcia-Layana, Alfredo] Univ Navarra, Dept Ophthalmol, Pamplona 31008, Spain, [Ciufo, Gianfranco] Univ Navarra, Dept Ophthalmol, Pamplona 31008, Spain, [Toledo, Estefania] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Martinez-Gonzalez, Miguel A.] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Corella, Dolores] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Fito, Montse] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Estruch, Ramon] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Fiol, Miguel] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Lapetra, Jose] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Serra-Majem, Lluis] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Pinto, Xavier] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Portillo, Maria P.] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Sorli, Jose V.] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Bullo, Monica] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Sala-Vila, Aleix] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Ros, Emilio] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Salas-Salvado, Jordi] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Aros, Fernando] Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid 28029, Spain, [Toledo, Estefania] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Martinez-Gonzalez, Miguel A.] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Estruch, Ramon] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Gomez-Gracia, Enrique] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Serra-Majem, Lluis] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Pinto, Xavier] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Bullo, Monica] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Salas-Salvado, Jordi] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Aros, Fernando] Inst Salud Carlos III ISC III, PREDIMED Prevenc Dieta Mediterranea Res Network R, Madrid 28029, Spain, [Toledo, Estefania] Univ Navarra, Dept Prevent Med & Publ Hlth, Pamplona 31008, Spain, [Martinez-Gonzalez, Miguel A.] Univ Navarra, Dept Prevent Med & Publ Hlth, Pamplona 31008, Spain, [Corella, Dolores] Univ Valencia, Dept Prevent Med, E-46010 Valencia, Spain, [Sorli, Jose V.] Univ Valencia, Dept Prevent Med, E-46010 Valencia, Spain, [Fito, Montse] Hosp Mar, Med Res Inst IMIM, Cardiovasc Risk & Nutr Regicor Study Grp, E-08003 Barcelona, Spain, [Estruch, Ramon] Univ Barcelona, Hosp Clin, August Pi Sunyer Inst Biomed Res IDIBAPS, Dept Internal Med, Barcelona 08036, Spain, [Gomez-Gracia, Enrique] Univ Malaga, Dept Prevent Med, Malaga 29016, Spain, [Fiol, Miguel] Univ Balear Islands, Inst Hlth Sci, Palma De Mallorca 07122, Spain, [Fiol, Miguel] Son Espases Hosp, Palma De Mallorca 07122, Spain, [Lapetra, Jose] Dist Sanitario Atenc Primaria Sevilla, Ctr Salud San Pablo, Dept Family Med, Seville 41007, Spain, [Serra-Majem, Lluis] Univ Las Palmas Gran Canaria, Dept Clin Sci, Las Palmas Gran Canaria 35001, Spain, [Pinto, Xavier] Univ Hosp Bellvitge, Lipids & Vasc Risk Units Internal Med, Barcelona 08907, Spain, [Portillo, Maria P.] Univ Basque Country, Dept Nutr & Food Sci, Nutr & Obes Grp, Vitoria 48940, Spain, [Portillo, Maria P.] Lucio Lascaray Res Ctr, Vitoria 48940, Spain, [Bullo, Monica] Rovira Virgili Univ, IISPV, Fac Med & Hlth Sci, Human Nutr Unit, Reus 43003, Spain, [Salas-Salvado, Jordi] Rovira Virgili Univ, IISPV, Fac Med & Hlth Sci, Human Nutr Unit, Reus 43003, Spain, [Vinyoles, Ernest] Univ Barcelona, Cap Mina, Barcelona 08930, Spain, [Sala-Vila, Aleix] Univ Barcelona, Hosp Clin, IDIBAPS, Lipid Clin Endocrinol & Nutr Serv, Barcelona 08036, Spain, [Ros, Emilio] Univ Barcelona, Hosp Clin, IDIBAPS, Lipid Clin Endocrinol & Nutr Serv, Barcelona 08036, Spain, [Aros, Fernando] Univ Hosp Araba, Dept Cardiol, Vitoria 01009, Spain, official funding agency for biomedical research of the Spanish government, Instituto de Salud Carlos III (ISCIII), Centro Nacional de Investigaciones Cardiovasculares, Fondo de Investigacion Sanitaria-Fondo Europeo de Desarrollo Regional, Ministerio de Ciencia e Innovacion, Fundacion Mapfre, Consejeria de Salud de la Junta de Andalucia, Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana, Regional Government of Navarra, and Miguel Servet I, ISCIII, Spain
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Male ,cumplimiento del paciente ,Mediterranean diet ,medicine.medical_treatment ,humanos ,Extra-virgin olive oil ,estudios de seguimiento ,Diet, Mediterranean ,Dieta mediterrània ,Cataract surgery ,Antioxidants ,law.invention ,0302 clinical medicine ,PREDIMED ,cataract ,cataract surgery ,nuts ,extra-virgin olive oil ,low-fat diet ,antioxidants ,Randomized controlled trial ,Cirurgia de cataractes ,law ,Risk Factors ,Prevalence ,Nuts ,Age-related cataract ,030212 general & internal medicine ,Diet, Fat-Restricted ,mediana edad ,Aged, 80 and over ,Ciències de la salut ,anciano ,Low-fat diet ,Nutrition and Dietetics ,dieta ,resultado del tratamiento ,Incidence (epidemiology) ,Incidence ,Hazard ratio ,Vitamins ,Metaanalysis ,Middle Aged ,Ciencias de la salud ,catarata ,Treatment Outcome ,Female ,Ciencias de la Salud [Materias Investigacion] ,lcsh:Nutrition. Foods and food supply ,Risk ,medicine.medical_specialty ,Zeaxanthin ,lcsh:TX341-641 ,incidencia ,Article ,Cataract ,Association ,03 medical and health sciences ,Mediterranean cooking ,Internal medicine ,Cuina mediterrània ,medicine ,factores de riesgo ,Humans ,Olive Oil ,Aged ,Cataractes -- Cirugia ,Nuclear cataract ,Proportional hazards model ,business.industry ,Prevention ,Health sciences ,Confidence interval ,Diet ,Surgery ,nueces ,Clinical trial ,Food Science ,Nutrition & Dietetics ,030221 ophthalmology & optometry ,Cataractes ,Patient Compliance ,business ,Follow-Up Studies - Abstract
Background: Cataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the lens components. A healthy overall dietary pattern, with the potential to reduce oxidative stress, has been suggested as a means to decrease the risk of developing cataract. We aimed to investigate the hypothesis that an intervention with a Mediterranean diet (MedDiet) rather than a low-fat diet could decrease the incidence of cataract surgery in elderly subjects. Methods: We included 5802 men and women (age range: 55-80 years) from the Prevencion con Dieta Mediterronea study (multicenter, parallel-group, randomized controlled clinical trial) who had not undergone cataract surgery. They were randomly assigned to one of three intervention groups: (1) a MedDiet enriched with extra-virgin olive oil (EVOO) (n = 1998); (2) a MedDiet enriched with nuts (n = 1914), and a control group recommended to follow a low-fat diet (n = 1890). The incidence of cataract surgery was recorded yearly during follow-up clinical evaluations. Primary analyses were performed on an intention-to-treat basis. Cox regression analyses were used to assess the relationship between the nutritional intervention and the incidence of cataract surgery. Results: During a follow-up period of 7.0 years (mean follow-up period: 5.7 years; median: 5.9 years), 559 subjects underwent cataract surgery. Two hundred and six participants from the MedDiet + EVOO group, 174 from the MedDiet + Nuts group, and 179 from the control group underwent cataract surgery. We did not observe a reduction in the incidence of cataract surgery in the MedDiet groups compared to the control group. The multivariable adjusted hazard ratios were 1.03 (95% confidence interval [CI]: 0.84-1.26, p = 0.79) for the control group versus the MedDiet + EVOO group and 1.06 (95% CI: 0.86-1.31, p = 0.58) for the control group versus the MedDiet + Nuts group. Conclusions: To our knowledge, this is the first large randomized trial assessing the role of a MedDiet on the incidence of cataract surgery. Our results showed that the incidence of cataract surgery was similar in the MedDiet with EVOO, MedDiet with nuts, and low-fat diet groups. Further studies are necessary to investigate whether a MedDiet could have a preventive role in cataract surgery., Supported by the official funding agency for biomedical research of the Spanish government, Instituto de Salud Carlos III (ISCIII), through grants provided to research networks specifically developed for the trial (RTIC G03/140, to Ramon Estruch; RTIC RD 06/0045, to Miguel Martinez-Gonzalez and through Centro de Investigacion Biomedica en Red de Fisiopatologia de la Obesidad y Nutricion [CIBEROBN]), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigacion Sanitaria-Fondo Europeo de Desarrollo Regional (PI04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, and P11/02505; PI13/00462), Ministerio de Ciencia e Innovacion (AGL-2009-13906-C02 and AGL2010-22319-C03), Fundacion Mapfre 2010, Consejeria de Salud de la Junta de Andalucia (PI0105/2007), Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana (ACOMP06109, GVA-COMP2010-181, GVACOMP2011-151, CS2010-AP-111, and CS2011-AP-042), and Regional Government of Navarra (P27/2011). AS-V holds a Miguel Servet I contract (CP12/03299), ISCIII, Spain.
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- 2017
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32. Predictors of short- and long-term adherence with a Mediterranean-type diet intervention: the PREDIMED randomized trial
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José V. Sorlí, Ana Sánchez-Tainta, Emilio Ros, Mary K. Downer, Alfredo Gea, Montserrat Fitó, Itziar Zazpe, Fernando Arós, Enrique Gómez-Gracia, Dolores Corella, Meir J. Stampfer, Lluis Serra-Majem, Miguel-Angel Martínez-González, Miquel Fiol, Ernest Vinyoles, Jordi Salas-Salvadó, Francisco Jose Garcia De-la-Corte, Xavier Pintó, Josep Basora, Ramon Estruch, Alimentació, Nutrició, Creixement i Salut Mental, Medicina i Cirurgia, Universitat Rovira i Virgili, and Universitat de Barcelona
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Male ,0301 basic medicine ,Gerontology ,modelos logísticos ,cumplimiento del paciente ,Mediterranean diet ,Health Behavior ,humanos ,Psychological intervention ,Medicine (miscellaneous) ,ejercicio físico ,Dietary predictors ,Diet, Mediterranean ,Logistic regression ,Dieta mediterrània ,law.invention ,0302 clinical medicine ,1479-5868 ,Randomized controlled trial ,Risk Factors ,law ,Nuts ,030212 general & internal medicine ,conducta sanitaria ,Dietary adherence ,mediana edad ,Dietoteràpia ,anciano ,Bioquímica y tecnología ,Nutrition and Dietetics ,dieta ,Hàbits alimentaris ,Middle Aged ,Biochemistry and technology ,Cardiovascular Diseases ,Female ,Dieta ,Waist Circumference ,medicine.medical_specialty ,Waist ,Food habits ,Promoció de la salut ,enfermedades cardiovasculares ,Physical Therapy, Sports Therapy and Rehabilitation ,Health Promotion ,Clinical nutrition ,Ciencias de la Salud::Nutrición y dietética [Materias Investigacion] ,Bioquímica i biotecnologia ,Short-term dietary adherence ,03 medical and health sciences ,Mediterranean cooking ,dietary intervention ,Cuina mediterrània ,ingesta energética ,medicine ,Humans ,factores de riesgo ,Adverse effect ,Olive Oil ,Exercise ,Dieta -- Mediterrània, Regió de la ,Aged ,conducta alimentaria ,030109 nutrition & dietetics ,perímetro abdominal ,Mediterranean Diet ,business.industry ,Research ,Feeding Behavior ,Diet ,PREDIMED trial ,nueces ,Dietary intervention ,Logistic Models ,Health promotion ,Spain ,Physical therapy ,Long-term dietary adherence ,Patient Compliance ,Energy Intake ,business ,Ciencias de la Salud::Endocrinología [Materias Investigacion] - Abstract
Background: Dietary intervention success requires strong participant adherence, but very few studies have examined factors related to both short-term and long-term adherence. A better understanding of predictors of adherence is necessary to improve the design and execution of dietary intervention trials. This study was designed to identify participant characteristics at baseline and study features that predict short-term and long-term adherence with interventions promoting the Mediterranean-type diet (MedDiet) in the PREvencion con DIeta MEDiterranea (PREDIMED) randomized trial. Methods: Analyses included men and women living in Spain aged 55-80 at high risk for cardiovascular disease. Participants were randomized to the MedDiet supplemented with either complementary extra-virgin olive oil (EVOO) or tree nuts. The control group and participants with insufficient information on adherence were excluded. PREDIMED began in 2003 and ended in 2010. Investigators assessed covariates at baseline and dietary information was updated yearly throughout follow-up. Adherence was measured with a validated 14-point Mediterranean-type diet adherence score. Logistic regression was used to examine associations between baseline characteristics and adherence at one and four years of follow-up. Results: Participants were randomized to the MedDiet supplemented with EVOO (n = 2,543; 1,962 after exclusions) or tree nuts (n = 2,454; 2,236 after exclusions). A higher number of cardiovascular risk factors, larger waist circumference, lower physical activity levels, lower total energy intake, poorer baseline adherence to the 14-point adherence score, and allocation to MedDiet + EVOO each independently predicted poorer adherence. Participants from PREDIMED recruiting centers with a higher total workload (measured as total number of persons-years of follow-up) achieved better adherence. No adverse events or side effects were reported. Conclusions: To maximize dietary adherence in dietary interventions, additional efforts to promote adherence should be used for participants with lower baseline adherence to the intended diet and poorer health status. The design of multicenter nutrition trials should prioritize few large centers with more participants in each, rather than many small centers., This study was funded by the Spanish Ministry of Health (ISCIII), PI1001407, Thematic Network G03/140, RD06/0045, FEDER (Fondo Europeo de Desarrollo Regional), and the Centre Catala de la Nutricio de l'Institut d'Estudis Catalans. The Fundacion Patrimonio Comunal Olivarero and Hojiblanca SA (Malaga, Spain), California Walnut Commission (Sacramento, CA), Borges SA (Reus, Spain), and Morella Nuts SA (Reus, Spain) donated the olive oil, walnuts, almonds and hazelnuts, respectively, used in the study. CIBEROBN is an initiative of ISCIII, Spain.
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- 2016
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33. The evaluation of a remote support program on quality of life and evolution of disease in COPD patients with frequent exacerbations
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Antonia Fuster, José Miguel Rodríguez González-Moro, Aurelio Arnedillo, Alonso Fernández-Nistal, Joan B. Soriano, Patricia García Sidro, Pilar de Lucas, Bernardino Alcazar, and María José Espinosa de los Monteros
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Male ,modelos logísticos ,cumplimiento del paciente ,Health Status ,humanos ,autocuidados ,Logistic regression ,Severity of Illness Index ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,Quality of life ,estudios prospectivos ,Surveys and Questionnaires ,Medicine ,evaluación de programas y proyectos de salud ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,mediana edad ,Univariate analysis ,COPD ,anciano ,Chronic obstructive pulmonary disease ,estado de salud ,Middle Aged ,Telemedicine ,Management ,Disease Progression ,Population study ,Female ,telemedicina ,Research Article ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Education ,Exacerbations ,03 medical and health sciences ,Patient Education as Topic ,progresión de la enfermedad ,Internal medicine ,Severity of illness ,Humans ,índice de gravedad de la enfermedad ,análisis multifactorial ,Aged ,business.industry ,medicine.disease ,Self Care ,Logistic Models ,030228 respiratory system ,Spain ,calidad de vida ,Multivariate Analysis ,Physical therapy ,Patient Compliance ,Observational study ,educación de pacientes como asunto ,business ,Program Evaluation - Abstract
Background: Chronic obstructive pulmonary disease (COPD) patients often present considerable individual medical burden in their symptoms, limitations, and well-being that complicate medical treatment. To improve their overall health status, while reducing the number of exacerbations, a multidisciplinary approach including different elements of care is needed. The aim of this study was to evaluate the effects of a remote support program on COPD patients at high risk of experiencing worsening of their disease and other health-related outcomes. Methods: An observational, multicenter, prospective study aimed at evaluating the impact of a 7-month remote support program on COPD patients in exacerbations control and changes in health status measured with the COPD assessment test (CAT). Factors associated with a clinically relevant decrease in CAT were assessed using a logistic regression analysis. Results: A total of 114 subjects started the program. The majority of the study population were males (81.6 %), retired (70.2 %), without academic qualifications or with a low level of education (68.4 %), and ex-smokers (79.8 %). The mean +/- SD age was 69.6 +/- 9.1 years and the BMI was 27.8 +/- 5.5 Kg/m(2). Overall, 41.9 % (95 % CI 31.9-52.0) patients, significantly improved health status (CAT decrease >= 2 points). Univariate analysis showed that significant improvement in CAT was associated with baseline CAT scores [high CAT score 19.2 (+/- 7.5) vs. low CAT score 12.4 (+/- 6.4); OR = 1.15, 95 % CI: 1.07-1.24; p < 0.001] and with being non-compliant [62.5 % (15/24) of non-compliant vs 34.7 % (24/69) of compliant patients significantly improved CAT scores; OR = 3.13, 95 % CI: 1.19-8.19; p = 0.021). After controlling for the effect of all variables in a multivariable logistic regression model, the only factor that remained significant was baseline CAT score. The proportion of smokers in the total population remained constant during the study. There was a significant reduction in the number of exacerbations after entering this remote support program with median -1 (IQR: -2, 0), (p < 0.001). The Morisky-Green questionnaire showed an increase of treatment compliance, namely at baseline, 25.8 % (24/93) of patients were noncompliant while in the end 66.7 % (16/24) of them became compliant) (p = 0.053). Conclusions: A remote support program for high-risk COPD patients results in an improvement of the patients' health status, particularly in those with initially poor health status, and it helps to reduce COPD exacerbations., The ESOPO study was funded by Takeda Pharmaceutical Spain SA.
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- 2016
34. Falta de adherencia al tratamiento fisioterapéutico en pacientes con trastornos musculoesqueléticos en una clínica docente en Lima, Perú
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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado., Objetivo Conocer la incidencia y los factores de riesgo asociados a la falta de adherencia al tratamiento fisioterapéutico en pacientes con dolor y trastornos músculo esqueléticos que asisten a una clínica docente en Lima, Perú. Materiales y métodos Estudio de cohorte retrospectivo, incluyó a todos los pacientes nuevos atendidos por dolor y trastornos musculoesqueléticos en el periodo 2012-2014. Se midieron la falta de adherencia (asistencia menor a las 8 sesiones indicadas) y los factores demográficos. Se calcularon los riesgos relativos crudos y ajustados (RRa). Resultados Se incluyó a 549 pacientes, el 68,3% fueron mujeres, el 37,2% tuvo 60 o más años, las lesiones más frecuentes se ubicaron en el miembro inferior (34,2%) y el dorso lumbar (24,6%). Se encontró una incidencia de falta de adherencia de 56,4% (IC del 95%, 52,2 a 60,7%) y estuvo asociada a residir lejos de la clínica (RRa: 1,34; IC del 95%, 1,16 a 1,57) y tener menos de 40 años (RRa: 1,27; IC del 95%, 1,04 a 1,54). Conclusión Existe una alta incidencia de falta de adherencia al tratamiento fisioterapéutico relacionado con la distancia y la edad de los pacientes, por lo que se deben buscar estrategias para aumentar la adherencia., Revisión por pares
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- 2016
35. Association between the Adherence to the International Guidelines for Cancer Prevention and Mammographic Density
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Adela Castelló, Leandro Prieto, María Ederra, Dolores Salas-Trejo, Carmen Vidal, Carmen Sánchez-Contador, Carmen Santamariña, Carmen Pedraz, Pilar Moreo, Nuria Aragonés, Beatriz Pérez-Gómez, Virginia Lope, Jesús Vioque, Marina Pollán, DDM-Spain research group, Instituto de Salud Carlos III, Ministerio de Sanidad y Consumo (España), and Federación Española de Cáncer de Mama
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medicine.medical_specialty ,cumplimiento del paciente ,Cross-sectional study ,humanos ,cribado sistemático ,Population ,Physical activity ,lcsh:Medicine ,neoplasias de la mama ,Breast Neoplasms ,Breast cancer ,Risk Factors ,Environmental health ,factores de riesgo ,Medicine ,Humans ,Mass Screening ,lcsh:Science ,education ,Mammary Glands, Human ,Mass screening ,Breast Density ,Gynecology ,education.field_of_study ,Multidisciplinary ,Cancer prevention ,business.industry ,lcsh:R ,MAMMOGRAPHIC DENSITY ,medicine.disease ,Postmenopause ,Cross-Sectional Studies ,Spain ,postmenopausia ,Patient Compliance ,lcsh:Q ,Smoking status ,Female ,business ,estudios transversales ,Research Article - Abstract
Introduction Mammographic density (MD) is considered a strong predictor of Breast Cancer (BC). The objective of the present study is to explore the association between MD and the compliance with the World Cancer Research Fund and the American Institute for Cancer Research (WCRF/AICR) recommendations for cancer prevention. Methods Data of 3584 women attending screening from a population-based multicenter cross-sectional study (DDM-Spain) collected from October 7, 2007 through July 14, 2008, was used to calculate a score that measures the level of compliance with the WCRF/AICR recommendations: R1)Maintain adequate body weight; R2)Be physically active; 3R)Limit the intake of high density foods; R4)Eat mostly plant foods; R5)Limit the intake of animal foods; R6)Limit alcohol intake; R7)Limit salt and salt preserved food intake; R8)Meet nutritional needs through diet. The association between the score and MD (assessed by a single radiologist using a semi-quantitative scale) was evaluated using ordinal logistic models with random center-specific intercepts adjusted for the main determinants of MD. Stratified analyses by menopausal status and smoking status were also carried out. Results A higher compliance with the WCRF/AICR recommendations was associated with lower MD (OR1-unit increase = 0.93 95%CI:0.86;0.99). The association was stronger in postmenopausal women (OR = 0.91 95%CI:0.84;0.99) and nonsmokers (OR = 0.87;95%CI:0.80;0.96 for nonsmokers, OR = 1.01 95%CI:0.91;1.12 for smokers, P-interaction = 0.042). Among nonsmokers, maintaining adequate body weight (OR = 0.81 95%CI:0.65;1.01), practicing physical activity (OR = 0.68 95%CI:0.48;0.96) and moderating the intake of high-density foods (OR = 0.58 95%CI:0.40;0.86) and alcoholic beverages (OR = 0.76 95%CI:0.55;1.05) were the recommendations showing the strongest associations with MD. Conclusions postmenopausal women and non-smokers with greater compliance with the WCRF/AICR guidelines have lower MD. These results may provide guidance to design specific recommendations for screening attendants with high MD and therefore at higher risk of developing BC., This study was supported by FIS PI060386 FIS (Health Research Fund) Research Grant; EC11-273 Research Grant from the Spanish Ministy of Health; CD110/00018 FIS Sara Borrell contract; FECMA 485 EPY 1170-10 grant from the Spanish Federation of Breast Cancer Patients.
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- 2015
36. Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study
- Author
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Carla H. van Gils, E. Riboli, Christos Tsironis, Anne-Claire Vergnaud, H. Bas Bueno-de-Mesquita, Laureen Dartois, José Ramón Quirós, Veronika Fedirko, Pietro Ferrari, Teresa Norat, Pagona Lagiou, Christina C. Dahm, Giovanna Masala, Timothy J. Key, Mark J. Gunter, Maria Wennberg, Kay-Tee Khaw, Verena Katzke, Petra H.M. Peeters, Aurelio Barricarte, Heather Ward, Nicholas J. Wareham, Anne Tjønneland, Lena Maria Nilsson, Bodil Ohlsson, Valeria Pala, Laure Dossus, Antonia Trichopoulou, Tilman Kühn, Heiner Boeing, Elisabete Weiderpass, Petra A. Wark, M. Dorronsoro, Carmen Navarro, Camilla Plambeck Hansen, Genevieve Buckland, Salvatore Panico, Marie-Christine Boutron-Ruault, María José Sánchez, Paolo Vineis, Peter D. Siersema, Karin Jirström, Dora Romaguera, Rosario Tumino, Mazda Jenab, Romaguera, Dora, Ward, Heather, Wark, Petra A, Vergnaud, Anne Claire, Peeters, Petra H, van Gils, Carla H, Ferrari, Pietro, Fedirko, Veronika, Jenab, Mazda, Boutron Ruault, Marie Christine, Dossus, Laure, Dartois, Laureen, Hansen, Camilla Plambeck, Dahm, Christina Catherine, Buckland, Genevieve, Sánchez, María José, Dorronsoro, Miren, Navarro, Carmen, Barricarte, Aurelio, Key, Timothy J, Trichopoulou, Antonia, Tsironis, Christo, Lagiou, Pagona, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Vineis, Paolo, Panico, Salvatore, Bueno de Mesquita, H. Ba, Siersema, Peter D, Ohlsson, Bodil, Jirström, Karin, Wennberg, Maria, Nilsson, Lena M, Weiderpass, Elisabete, Kühn, Tilman, Katzke, Verena, Khaw, Kay Tee, Wareham, Nick J, Tjønneland, Anne, Boeing, Heiner, Quirós, José R, Gunter, Marc J, Riboli, Elio, Norat, Teresa, Department of Medical and Clinical Genetics, Medicum, BMC, BMC, Department of Epidemiology and Public Health, Imperial College London, Instituto de Investigación Sanitaria de Palma (IdISPa), Hospital Universitario Son Espases, CIBER Fisiopatología de la Obesidad y Nutrición ( (CIBEROBN)), Instituto de Salud Carlos III [Madrid] (ISC), Department of Primary Care and Public Health, Department of Epidemiology, University Medical Center [Utrecht]-Julius Center for Health Sciences and Primary Care, Nutrition and Metabolism Section, International Agency for Cancer Research (IACR), Emory University [Atlanta, GA]-Rollins School of Public Health-Winship Cancer Institute, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Section for Epidemiology, Aarhus University [Aarhus], Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology (ICO-IDIBELL)-Cancer Epidemiology Research Programme, Granada Cancer Registry, Andalusian School of Public Health [Granada], Consorcio de Investigación Biomédica en Red especializado en Epidemiología y Salud Pública (CIBERESP), Los Centros de Investigación Biomédica en Red (CIBER), Murcia Regional Health Council [Murcia], Department of Health and Social Sciences, Universidad de Murcia, Navarre Public Health Institute, Cancer Epidemiology Unit, University of Oxford, Hellenic Health Foundation, Bureau of Epidemiologic Research, Academy of Athens, Department of Hygiene, Epidemiology and Medical Statistics, Harvard School of Public Health, Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Tumori - National Cancer Institute [Milan], Cancer Registry and Histopathology Unit, Department of Oncology-Civile - M.P.Arezzo Hospital, Human Genetics Foundation (HuGeF), Università degli studi di Torino = University of Turin (UNITO), Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II = Università degli studi di Napoli Federico II, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya = Universiti Malaya [Kuala Lumpur, Malaisie] (UM), Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment [Bilthoven] (RIVM), Department of Gastroenterology and Hepatology, University Medical Center [Utrecht], Division of Internal Medicine, Skane University Hospital [Malmo], Lund University [Lund]-Lund University [Lund], Division of Oncology and Pathology, Lund University [Lund], Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Arctic Research Centre, Department of Community Medicine, The Arctic University of Norway [Tromsø, Norway] (UiT), Department of Research, Cancer Registry of Norway, Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet [Stockholm], Genetic Epidemiology Group [Helsinki], Folkhälsan Research Center, Faculty of Medecine [Helsinki], Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Faculty of Medecine [Helsinki], Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Division of Cancer Epidemiology, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Clinical Gerontology Unit, University of Cambridge [UK] (CAM), MRC Epidemiology Unit, University of Cambridge [UK] (CAM)-Institute of Metabolic Science, Danish Cancer Society Research Center, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, Public Health Directorate, Khaw, Kay-Tee [0000-0002-8802-2903], Wareham, Nicholas [0000-0003-1422-2993], Apollo - University of Cambridge Repository, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), University of Oxford [Oxford], Università degli studi di Torino (UNITO), University of Naples Federico II, University of Malaya, The Arctic University of Norway, University of Helsinki-University of Helsinki-Faculty of Medecine [Helsinki], University of Helsinki-University of Helsinki, [Romaguera,D, Ward,H, Vergnaud,A, Peeters,PH, Vineis,P, Bueno-de-Mesquita,HB, Gunter, MJ, Riboli,E, Norat,T] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. [Romaguera,D] Instituto de Investigación Sanitaria de Palma (IdISPa), Hospital Universitario Son Espases, Palma de Mallorca, Spain. [Romaguera,D] CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. [Wark,PA] Global eHealth Unit, Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UK. [Peeters,PH, Gils, CH] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands. [Ferrari,P, Jenab,M] International Agency for Cancer Research (IARC), Lyon CEDEX, France. [Fedirko,V] Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA. [Fedirko,V] Winship Cancer Institute, Emory University, Atlanta, USA. [Boutron-Ruault,M, Dossus,L, Dartois,L] Inserm (Institut National de la Santé et de la Recherche Médicale), Centre for Research in Epidemiology and Population Health (CESP), Vaillant, Villejuif, Cedex, France. [Boutron-Ruault,M, Dartois,L] Univ Paris Sud, Villejuif, France. [Boutron-Ruault,M, Dartois,L] Gustave Roussy, Villejuif, France. [Hansen,CP, Dahm,CC] Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus C, Denmark. [Buckland,G] Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain. [Sánchez,MJ] Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs. GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain. [Sánchez,MJ, Dorronsoro,M, Navarro,C, Barricarte,A] CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. [Dorronsoro,M] Public Health Direction and Biodonostia Basque Regional Health Department, San Sebastian, Spain. [Navarro,C] Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain. Department of Health and Social Sciences, Universidad de Murcia, Campus Universitario de Espinardo, Murcia, Spain. [Barricarte,A] Navarre Public Health Institute, Pamplona, Spain. [Key,TJ] Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford UK. [Trichopoulou,A, Tsironis,C] Hellenic Health Foundation, Athens, Greece . [Trichopoulou,A, Lagiou,P] Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece. [Lagiou,P] Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece. [Lagiou,P] Department of Epidemiology, Harvard School of Public Health, Boston, USA. [Masala,G] Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence, Italy. [Pala,V] Epidemiology and Prevention Unit, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milan, Italy. [Tumino,R] Cancer Registry and Histopathology Unit, 'Civic – M.P. Arezzo' Hospital, Ragusa, Italy. [Vineis,P] HuGeF Foundation, Turin, Italy. [Panico,S] Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy. [Bueno-de-Mesquita,HB] Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven The Netherlands. [Bueno-de-Mesquita,HB, Siersema,PD] Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands. [Bueno-de-Mesquita,HB] Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. [Ohlsson,B] Division of Internal Medicine, Department of Clinical Sciences, Skane University Hospital, Malmo, Lund University, Lund, Sweden. [Jirström,K] Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden. [Wennberg,M] Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden. [Nilsson,LM] Arctic Research Centre, Umeå University, Umeå, Sweden. [Weiderpass,E] Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, ISM - Universitetet i Tromsø, Tromsø, Norway. Department of Research, Cancer Registry of Norway, Majorstuen Oslo, Norway. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Department of Genetic Epidemiology, Folkhälsan Research Center, Folkhälsan Research Center, Biomedicum 1, University of Helsinki, Helsinki, Finland. [Kühn,T, Katzke,V] German Cancer Research Center (DKFZ), Division of Cancer Epidemiology Im Neuenheimer Feld 581, Heidelberg, Germany. [Khaw,K] University of Cambridge School of Clinical Medicine, Clinical Gerontology Unit Box 251, Addenbrooke’s Hospital, Cambridge, UK. [Wareham,NJ] MRC Epidemiology Unit, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK. [Tjønneland,A] Danish Cancer Society Research Center, Copenhagen, Denmark. [Boeing,H] Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany. [Quirós,JR] Public Health Directorate, Oviedo Asturias, Spain., This study was funded by the World Cancer Research Fund (WCRF) International Regular Grant Programme (Grant number 2009/44). Dora Romaguera holds a Ramon y Cajal contract (Ministerio de Economía y Competitividad, Spain and European Regional Development Fund, RYC-2011-08796). In addition, EPIC investigators acknowledge funding from the following agencies: Europe Against Cancer Program of the European Commission (SANCO), German Cancer Aid, German Cancer Research Center (DKFZ), German Federal Ministry of Education and Research (BMBF), Danish Cancer Society, Catalan Institute of Oncology, Spain, Health Research Fund (FIS) of the Spanish Ministry of Health, Spanish Regional Governments of Andalucía, Asturias, Basque Country, Murcia (no. 6236) and Navarra, ISCIII RCESP exp. C03/09 and ISCIII RETICC RD06/0020/0091, Spain, Cancer Research UK, Medical Research Council, United Kingdom, The Hellenic Health Foundation, Greece, Italian Association for Research on Cancer (AIRC), Italian National Research Council, Fondazione-Istituto Banco Napoli, Italy, Dutch Ministry of Public Health, Welfare and Sports, Dutch Prevention Funds, LK Research Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), The Netherlands, Swedish Cancer Society, Swedish Scientific Council, Regional Government of Skåne, Sweden, Helga—Nordic Center of Excellence Programme in Nutrition and Health, French League against Cancer (LNCC), National Institute for Health and Medical Research (INSERM), France, Mutuelle Générale de l'Education Romaguera et al. BMC Medicine (2015) 13:107 Page 10 of 12 Nationale (MGEN), France, 3 M Co., France, Gustave Roussy Institute (IGR), France, and and General Councils of France. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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Male ,physical activity ,0302 clinical medicine ,estudios prospectivos ,Prospective Studies ,estudios de cohortes ,mediana edad ,Aged, 80 and over ,anciano ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Motor Activity [Medical Subject Headings] ,dieta ,Incidence ,Hazard ratio ,COLON-CANCER ,General Medicine ,adulto ,3. Good health ,Näringslära ,[SDV] Life Sciences [q-bio] ,030220 oncology & carcinogenesis ,estilo de vida ,Cohort ,Dieta ,Estilo de Vida ,RESEARCH FUND/AMERICAN INSTITUTE ,Cohort study ,Human ,medicine.medical_specialty ,Concordance ,European Continental Ancestry Group ,DIAGNOSIS ,incidencia ,White People ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Càncer colorectal ,Neoplasias Colorrectales ,BREAST-CANCER ,Humans ,Life Style ,Aged ,Cancer prevention ,Proportional hazards model ,Physical activity ,Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [Medical Subject Headings] ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life Style [Medical Subject Headings] ,weight ,LIFE-STYLE FACTORS ,Colorectal cancer ,REPRODUCTIVE HISTORY ,Prospective Studie ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings] ,Cancer and Oncology ,Proportional Hazards Model ,grupo de ascendencia continental europea ,Estudios de Cohortes ,Gerontology ,cumplimiento del paciente ,Survival ,modelos de riesgos proporcionales ,VDP::Medisinske Fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803 ,[SDV]Life Sciences [q-bio] ,humanos ,Colorectal Neoplasm ,Alcohol consumption ,Breast cancer ,Prospective study ,Named Groups::Persons::Survivors [Medical Subject Headings] ,Cohort Studies ,030212 general & internal medicine ,Prospective cohort study ,Non-U.S. Gov't ,2. Zero hunger ,Medicine(all) ,RISK ,Nutrition and Dietetics ,Healthy lifestyle ,Diet ,Weight ,Research Support, Non-U.S. Gov't ,Public Health, Global Health, Social Medicine and Epidemiology ,Middle Aged ,European Prospective Investigation into Cancer and Nutrition ,VDP::Medical disciplines: 700::Health sciences: 800::Epidemiology medical and dental statistics: 803 ,NUTRITION ,Female ,Colorectal Neoplasms ,Research Article ,Adult ,neoplasias colorrectales ,3122 Cancers ,RECREATIONAL PHYSICAL-ACTIVITY ,Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0] ,colorectal cancer ,Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings] ,Research Support ,survival ,Sobrevivientes ,healthy lifestyle ,Internal medicine ,medicine ,Journal Article ,Proportional Hazards Models ,Actividad Motora ,business.industry ,Physical fitness ,BODY-MASS INDEX ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Other Clinical Medicine ,3121 General medicine, internal medicine and other clinical medicine ,Patient Compliance ,Cohort Studie ,business ,diet ,Condició física - Abstract
Background: Cancer survivors are advised to follow lifestyle recommendations on diet, physical activity, and body fatness proposed by the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) for cancer prevention. Previous studies have demonstrated that higher concordance with these recommendations measured using an index score (the WCRF/AICR score) was associated with lower cancer incidence and mortality. The aim of this study was to evaluate the association between pre-diagnostic concordance with WCRF/AICR recommendations and mortality in colorectal cancer (CRC) patients. Methods: The association between the WCRF/AICR score (score range 0-6 in men and 0-7 in women; higher scores indicate greater concordance) assessed on average 6.4 years before diagnosis and CRC-specific (n = 872) and overall mortality (n = 1,113) was prospectively examined among 3,292 participants diagnosed with CRC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort (mean follow-up time after diagnosis 4.2 years). Multivariable Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality. Results: The HRs (95% CIs) for CRC-specific mortality among participants in the second (score range in men/women: 2.25-2.75/3.25-3.75), third (3-3.75/4-4.75), and fourth (4-6/5-7) categories of the score were 0.87 (0.72-1.06), 0.74 (0.61-0.90), and 0.70 (0.56-0.89), respectively (P for trend, We would like to acknowledge the contribution of all participants in the study. This study was funded by the World Cancer Research Fund (WCRF) International Regular Grant Programme (Grant number 2009/44). Dora Romaguera holds a Ramon y Cajal contract (Ministerio de Economia y Competitividad, Spain and European Regional Development Fund; RYC-2011-08796). In addition, EPIC investigators acknowledge funding from the following agencies: Europe Against Cancer Program of the European Commission (SANCO); German Cancer Aid; German Cancer Research Center (DKFZ); German Federal Ministry of Education and Research (BMBF); Danish Cancer Society; Catalan Institute of Oncology, Spain; Health Research Fund (FIS) of the Spanish Ministry of Health; Spanish Regional Governments of Andalucia, Asturias, Basque Country, Murcia (no. 6236) and Navarra; ISCIII RCESP exp. C03/09 and ISCIII RETICC RD06/0020/0091, Spain; Cancer Research UK; Medical Research Council, United Kingdom; The Hellenic Health Foundation, Greece; Italian Association for Research on Cancer (AIRC); Italian National Research Council; Fondazione-Istituto Banco Napoli, Italy; Dutch Ministry of Public Health, Welfare and Sports, Dutch Prevention Funds, LK Research Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), The Netherlands; Swedish Cancer Society; Swedish Scientific Council; Regional Government of Skane, Sweden; Helga-Nordic Center of Excellence Programme in Nutrition and Health; French League against Cancer (LNCC); National Institute for Health and Medical Research (INSERM), France; Mutuelle Generale de l'Education Nationale (MGEN), France; 3 M Co., France; Gustave Roussy Institute (IGR), France; and General Councils of France.
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- 2014
37. Lifestyles and risk factors associated with adherence to the Mediterranean diet: a baseline assessment of the PREDIMED trial
- Author
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Enrique Gómez-Gracia, Rosa M. Lamuela-Raventós, José V. Sorlí, María P. Portillo, Javier Díez-Espino, Fernando Arós, Dolores Corella, Ramon Estruch, Miquel Fiol, Miguel Ángel Martínez-González, Ernest Vinyoles, José Lapetra, Emily A Hu, Jordi Salas-Salvadó, Xavier Pintó, Lluis Serra-Majem, Estefanía Toledo, Emilio Ros, and Universitat de Barcelona
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Gerontology ,Male ,cumplimiento del paciente ,distribución territorial de la población ,Mediterranean diet ,Non-Clinical Medicine ,Epidemiology ,humanos ,Diet, Mediterranean ,Cardiovascular ,law.invention ,Cohort Studies ,Clinical trials ,Endocrinology ,Randomized controlled trial ,law ,Residence Characteristics ,Risk Factors ,Food choice ,mediana edad ,Epidemiological Methods ,Aged, 80 and over ,anciano ,Multidisciplinary ,Hàbits alimentaris ,dieta ,Middle Aged ,Health Education and Awareness ,Cardiovascular Diseases ,estilo de vida ,Observational Studies ,Medicine ,Dieta ,Female ,Public Health ,Research Article ,Clinical Research Design ,Food habits ,Science ,enfermedades cardiovasculares ,Dietary pattern ,factores socioeconómicos ,medicine ,factores de riesgo ,Humans ,Clinical Trials ,Obesity ,Statistical Methods ,Socioeconomic status ,Life Style ,Cardiovascular Disease Epidemiology ,Aged ,Nutrition ,Health Care Policy ,business.industry ,PREDIMED study ,Odds ratio ,Anthropometry ,medicine.disease ,Lifestyle ,Confidence interval ,Diet ,Socioeconomic Factors ,Risk factors ,Case-Control Studies ,Patient Compliance ,Preventive Medicine ,business ,Demography ,Assaigs clínics - Abstract
Background: The traditional Mediterranean dietary pattern (MedDiet) is associated with longevity and low rates of cardiovascular disease (CVD). However, there is little information on who is more likely to follow this food pattern. Aim: To evaluate how different factors are associated with lower MedDiet adherence in older Spanish subjects. Methods: We included 7305 participants (men aged 55-80 y, women 60-80 y) at high-risk of CVD recruited into the PREDIMED trial (ISRCTN35739639). Socioeconomic, anthropometric, lifestyle characteristics and CVD risk factors were recorded. A validated 14-item questionnaire was used to evaluate MedDiet adherence at baseline. Multivariate models were used to estimate odds ratios (OR) and 95% confidence intervals for lower adherence to the MedDiet (, Supported by the official funding agency for biomedical research of the Spanish government, Instituto de Salud Carlos III (ISCIII), through grants provided to research networks specifically developed for the trial (RTIC G03/140, to Dr. Estruch; RTIC RD 06/0045, to Dr. Martinez-Gonzalez and through Centro de Investigacion Biomedica en Red de Fisiopatologia de la Obesidad y Nutricion [CIBERobn]), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigacion Sanitaria-Fondo Europeo de Desarrollo Regional (PI04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, and P11/02505), Ministerio de Ciencia e Innovacion (AGL-2009- 13906-C02, AGL2010-22319-C03 and SAF2009-12304), Fundacion Mapfre 2010, Consejeria de Salud de la Junta de Andalucia (PI0105/2007), Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana (ACOMP06109, GVACOMP2010-181, GVACOMP2011-151, CS2010- AP-111, CS2011-AP-042, BEST11-263, BEST/2011/261, GVACOMP2011-151, ACOMP/2011/145 and ACOMP/2012/190), and Regional Government of Navarra (P27/2011). Dr. Toledo is supported by a Rio Hortega post-residency fellowship of ISCIII, Ministry of Economy and Competitiveness, Spanish Government and by the Fundacion Mutua Madrilena. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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- 2013
38. Prevalencia y factores asociados a la no adherencia en el tratamiento farmacológico de mantenimiento en adultos con trastorno afectivo bipolar*
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Pardo Cely, Elvia Elena, Fierro, Marco, and Ibánez Pinilla, Milciades
- Subjects
severidad de la enfermedad ,adherencia farmacológica ,cumplimiento del paciente ,estigma social ,Bipolar disorder ,medication adherence ,Trastorno bipolar ,severity of illness index ,social stigma ,patient compliance - Abstract
Introducción: Este artículo busca determinar la prevalencia y los factores asociados a la no adherencia en el tratamiento de mantenimiento de pacientes adultos con diagnóstico de trastorno afectivo bipolar. Métodos. Estudio de corte transversal con 124 pacientes ambulatorios. Se evaluó la adherencia al tratamiento de mantenimiento con el cuestionario de Morisky-Green. Se usó, además, la escala de impresión clínica global modificada para el trastorno bipolar (CGI-BPM) y el test de Apgar familiar. Resultados: La prevalencia de la no adherencia al tratamiento farmacológico de mantenimiento fue del 29,8%, y fue mayor para las mujeres (64,9%) que para los hombres (35,1%), si bien la diferencia no fue estadísticamente significativa (p=0,17). Los factores que de manera estadísticamente significativa se asociaron a la no adherencia fueron: mayor gravedad de la enfermedad (OR 1,9), antecedente de no adherencia (39%, p=0,001), menor insight (87%, RP 4,65), haberse sentido estigmatizado por padecer la enfermedad (50%, RP 6,2), el hábito de fumar (47,6%, p=0,048), mayor disfunción familiar, no contar con familiares que ayuden al paciente en la toma del medicamento (73%, p=0,001) y percepción negativa del médico tratante (100%, p=0,001). Conclusiones: La prevalencia estuvo dentro del rango de otros estudios publicados. Los factores asociados a la no adherencia fueron: mayor gravedad de la enfermedad, sentirse estigmatizado, antecedentes de falta de adherencia, pobre insight, el hábito de fumar, disfunción familiar, no tener familiares que ayuden a tomar el medicamento y la percepción negativa del médico tratante. Introduction: This study aims to determine the prevalence and factors associated with non-adherence in maintenance treatment of adult patients diagnosed with bipolar disorder. Methods: Cross sectional study with 124 patients. Adherence to treatment was evaluated by the Morisky-Green Test. A structured questionnaire was applied. It included variables associated with demographics factors and factors related to the patient, illness, treatment, family, therapeutic relationship, and health system. The Global Impression Scale Modified for Bipolar Disorder (CGI-BPM) and Family Apgar were used as well. Results: The prevalence of non-adherence to maintenance drug treatment was 29.8%. It was greater in women (64.9%) than men (35.1%), although this difference was not statistically significant (p = 0.17). The factors statistically significant associated with non-adherence factors were: Increased severity of the disease (OR 1.9), history of non-adherence (39% P=0,001), negative perception of the psychiatrist (100%, P=0.001), less insight (87%, RP4.65), greater stigma (50%, RP 6.2), having no family member to remind taking the drug (73%, P=0.001). Conclusions: The prevalence was inside the range found in other studies. The statistically significant factors associated with non-adherence were: Severity of disease, history of non-compliance, stigma, no family support, poor insight, smoking habit, and negative perception of the psychiatrist.
- Published
- 2011
39. Reseña de 'La mente de los violentos' de Sanmartín J
- Author
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CINDY CAROLINA CAUICH-SONDA
- Subjects
severidad de la enfermedad ,adherencia farmacológica ,cumplimiento del paciente ,estigma social ,Trastorno bipolar ,Psicología - Abstract
Introducción: Este artículo busca determinar la prevalencia y los factores asociados a la no adherencia en el tratamiento de mantenimiento de pacientes adultos con diagnóstico de trastorno afectivo bipolar. Métodos: Estudio de corte transversal con 124 pacientes ambulatorios. Se evaluó la adherencia al tratamiento de mantenimiento con el cuestionario de Morisky-Green. Se usó, además, la escala de impresión clínica global modificada para el trastorno bipolar (CGI-BPM) y el test de Apgar familiar. Resultados: La prevalencia de la no adherencia al tratamiento farmacológico de mantenimiento fue del 29,8%, y fue mayor para las mujeres (64,9%) que para los hombres (35,1%), si bien la diferencia no fue estadísticamente significativa (p=0,17). Los factores que de manera estadísticamente significativa se asociaron a la no adherencia fueron: mayor gravedad de la enfermedad (OR 1,9), antecedente de no adherencia (39%, p=0,001), menor insight (87%, RP 4,65), haberse sentido estigmatizado por padecer la enfermedad (50%, RP 6,2), el hábito de fumar (47,6%, p=0,048), mayor disfunción familiar, no contar con familiares que ayuden al paciente en la toma del medicamento (73%, p=0,001) y percepción negativa del médico tratante (100%, p=0,001). Conclusiones: La prevalencia estuvo dentro del rango de otros estudios publicados. Los factores asociados a la no adherencia fueron: mayor gravedad de la enfermedad, sentirse estigmatizado, antecedentes de falta de adherencia, pobre insight, el hábito de fumar, disfunción familiar, no tener familiares que ayuden a tomar el medicamento y la percepción negativa del médico tratante.
- Published
- 2010
40. Adherence to treatment: what is done in Sweden?: practice, education and research
- Author
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Björn Södergård
- Subjects
mesh:Sweden ,Sweden ,Farmacéuticos ,International Series: Adherence ,business.industry ,MEDLINE ,Pharmacy ,Patient compliance ,mesh:Patient compliance ,Pharmacists ,Practice education ,Deregulation ,Nursing ,Cumplimiento del paciente ,Medicine ,Suecia ,mesh:Pharmacists ,business - Abstract
Objective: The objective of this review was to identify the practice, education and research of pharmacists in Sweden in regard to adherence to treatment. Methods: Medline was searched up to the end of February 2008. In addition to the Medline search performed, other available sources were also used to identify relevant articles. Results: No adherence-specific programs have been implemented in Swedish pharmacies. No adherence-specific courses are provided in Swedish Universities educating pharmacists. The adherence-related research has so far mainly focused on refill non-adherence, primary non-adherence and patient reported non-adherence and readiness to treatment. Conclusions: Adherence-related practice and education of pharmacists will probably change due to the deregulation of the pharmacy market that will take place in the near future in Sweden. Research on adherence will need to be strengthened in the sense that it has so far not been guided by adherence-related theoretical frameworks, despite the fact that there are several theories to hand that try to explain adherence. Objetivo: El objetivo de esta revisión fue identificar la práctica, educación e investigación de los farmacéuticos en Suecia en relación a la adherencia al tratamiento. Métodos: Se buscó en Medline a finales de febrero de 2008. Además de la búsqueda en Medline, se utilizaron otras fuentes disponibles para identificar artículos relevantes. Resultados: No se han implantado programas específicos de adherencia en las farmacias suecas. No se han proporcionado cursos específicos en las universidades suecas para educar a los farmacéuticos. La investigación relacionada con adherencia ha estado fundamentalmente centrada en no cumplimiento de las repeticiones de medicamentos, no cumplimiento primario y incumplimiento comunicado por el paciente y disponibilidad al tratamiento. Conclusiones: La práctica y la educación de farmacéuticos relacionadas con la adherencia probablemente cambien debido a la desregulación del mercado farmacéutico que tendrá lugar en Suecia en un futuro cercano. La investigación en adherencia necesitará ser reforzada ya que no se ha basado en marcos teóricos de adherencia cumplimiento, a pesar de que existen varias las teorías que intentan explicar el incumplimiento.
- Published
- 2008
41. Investigation of barriers to clinical practice guideline-recommended pharmacotherapy in the treatment of COPD
- Author
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Cynthia Hartsfield, Sarah J. Billups, Lea C. Price, and Melissa A. Rice
- Subjects
mesh:Practice Guidelines ,medicine.medical_specialty ,Chronic Obstructive ,Psychological intervention ,Enfermedad pulmonaria obstructiva crónica ,Guías clínicas ,Pulmonary Disease ,Pharmacotherapy ,Drug Therapy ,Cumplimiento del paciente ,mesh:Pulmonary Disease ,mesh:Drug Therapy ,medicine ,mesh:Patient Compliance ,Medical prescription ,Intensive care medicine ,Practice Guidelines ,Original Research ,COPD ,business.industry ,Medical record ,Estados Unidos ,Retrospective cohort study ,Guideline ,medicine.disease ,United States ,Physical therapy ,Patient Compliance ,mesh:United States ,business ,Farmacoterapia ,Adverse drug reaction ,mesh:Chronic Obstructive - Abstract
Background: The adoption of clinical practice guideline recommendations for COPD is suboptimal. Determining the barriers to the implementation of these practice guidelines may help improve patient care. Objective: To determine whether barriers to the use of pharmacotherapy according to practice guidelines are related primarily to patient or prescriber factors. Methods: Retrospective cohort study. Members of a health maintenance organization identified as having spirometry-defined COPD ranging from stage II to IV. Electronic medical records were reviewed for documentation of the following: 1) patient affordability issues, 2) history of an adverse drug reaction, 3) history of inefficacy to therapy, and 4) prescription history. Results: A total of 111 medical records were reviewed. There were 51% of patients who had not filled medications that had been prescribed in accordance with guidelines and 43% did not have the guideline recommended medications prescribed in the previous year. Only 4% and 2% of patients had documented inefficacy and affordability issues, respectively. There were no reported cases of adverse drug reactions. Conclusions: This study provides insight to the acceptance of COPD treatment recommendations by patients and providers. Further research is needed to design interventions to reduce barriers and optimize COPD treatment. Antecedentes: La adopción de recomendaciones de las guías de práctica clínica es sub-optima. Determinar las barreras para la implantación de estas guías de práctica puede ayudara mejorar la atención al paciente. Objetivo: Determinar si las barreras para el uso de la farmacoterapia de acuerdo con las guías de práctica están fundamentalmente relacionadas con variables del paciente o del prescriptor. Métodos: Estudio de cohorte retrospectivo. Miembros de una organización de gestión de la salud identificados por tener EPOC definida por espirometría entre los estadios II a IV. Se revisaron los historiales médicos electrónicos para documentar lo siguiente: 1) capacidad económica del paciente, 2) historial de reacciones adversas, 3) historial de ineficacia del tratamiento, y 4) historial de prescripción. Resultados: Se revisó un total de 111 historiales médicos. Hubo un 51% de pacientes que no había completado la medicación que le habías ido prescrita de acuerdo con las guías y un 43% no había recibido las prescripciones recomendadas en las guías en el último año. Sólo un 4% y un 2% de pacientes había documentado problemas de ineficacia y de capacidad económica, respectivamente. No había registrados casos de reacciones adversas medicamentosas. Conclusiones: Este estudio proporciona una visión de la aceptación del as recomendaciones del tratamiento de EPOC por los pacientes y los proveedores. Se necesita un investigación para diseñar intervenciones que reduzcan las barreras y optimicen el tratamiento del a EPOC.
- Published
- 2007
42. Frecuencia de factores de riesgo cardiovascular en pacientes hipertensos en un hospital de segundo nivel
- Abstract
Introducción: La hipertensión es un problema de salud muy frecuente y está relacionada con enfermedades cardiocerebrovasculares. La adherencia al tratamiento se ha asociado a la reducción de las complicaciones y la mortalidad. Métodos. Se efectuó un estudio descriptivo en 142 pacientes hipertensos que hacían parte de una base de datos. Se aplicó el Cuestionario de adherencia al tratamiento Martín-Bayarre-Grau (MBG). Resultados. El 50% tenía sobrepeso. 51% se clasificó como parcialmente adheridos al tratamiento. En el momento de la evaluación el 50% de los pacientes tenían una cifra de tensión arterial sistólica alta y el 40% una cifra de tensión arterial diastólica elevada. Conclusión. EL programa debe vigilar en forma rutinaria la adherencia de los pacientes al tratamiento así como monitorear los riesgos por sobrepeso y sedentarismo.
- Published
- 2011
43. Adherence to treatment: what is done in Sweden? Practice, education and research.
- Abstract
Objective: The objective of this review was to identify the practice, education and research of pharmacists in Sweden in regard to adherence to treatment. Methods: Medline was searched up to the end of February 2008. In addition to the Medline search performed, other available sources were also used to identify relevant articles. Results: No adherence-specific programs have been implemented in Swedish pharmacies. No adherence-specific courses are provided in Swedish Universities educating pharmacists. The adherencerelated research has so far mainly focused on refill non-adherence, primary non-adherence and patient reported non-adherence and readiness to treatment. Conclusions: Adherence-related practice and education of pharmacists will probably change due to the deregulation of the pharmacy market that will take place in the near future in Sweden. Research on adherence will need to be strengthened in the sense that it has so far not been guided by adherence-related theoretical frameworks, despite the fact that there are several theories to hand that try to explain adherence., RESUMEN Objetivo: El objetivo de esta revisión fue identificar la práctica, educación e investigación de los farmacéuticos en Suecia en relación a la adherencia al tratamiento. Métodos: Se buscó en Medline a finales de febrero de 2008. Además de la búsqueda en Medline, se utilizaron otras fuentes disponibles para identificar artículos relevantes. Resultados: No se han implantado programas específicos de adherencia en las farmacias suecas. No se han proporcionado cursos específicos en las universidades suecas para educar a los farmacéuticos. La investigación relacionada con adherencia ha estado fundamentalmente centrada en no cumplimiento de las repeticiones de medicamentos, no cumplimiento primario y incumplimiento comunicado por el paciente y disponibilidad al tratamiento. Conclusiones: La práctica y la educación de farmacéuticos relacionadas con la adherencia probablemente cambien debido a la desregulación del mercado farmacéutico que tendrá lugar en Suecia en un futuro cercano. La investigación en adherencia necesitará ser reforzada ya que no se ha basado en marcos teóricos de adherencia cumplimiento, a pesar de que existen varias las teorías que intentan explicar el incumplimiento
- Published
- 2008
44. The effect of patient satisfaction with pharmacist consultation on medication adherence: an instrumental variable approach
- Abstract
RESUMEN Hay pocos estudios que cuantifiquen el impacto de la satisfacción del paciente con la consulta farmacéutica sobre la adherencia a la medicación. Objetivos: El objetivo de este estudio es evaluar el efecto de la satisfacción del paciente con los servicios de consulta farmacéutica sobre la adherencia a la medicación en una gran organización de gestión de cuidados. Métodos: Analizamos datos de un cuestionario de satisfacción de 6.916 pacientes que habían usado consultas farmacéuticas de la Kaiser Permanente Southern California desde 1993 a 1996. Comparamos, tratando la satisfacción del paciente como exógena, en un modelo probit de una ecuación, con un modelo proibit bivariado donde la satisfacción se trató como endógena. Se utilizaron diferentes conjuntos de variables, incluyendo medidas del bienestar emocional de los pacientes y propensión de los pacientes a adquirir sus medicamentos en una farmacia no Kaiser Permanente (KP). Se usó el test Smith-Blundell para probar si la satisfacción del paciente era endógena. Se usaron test de sobre-identificación para probar la validez de las variables instrumentales. El instrumento débil de Staiger- Stock fue utilizado para evaluar el poder explicativo de las variables instrumentales. Resultados: Todos los métodos indicaron que el método de variables instrumentales utilizado tuvo poder explicativo. El modelo probit de una ecuación indicó que el efecto de la satisfacción del paciente con la consulta farmacéutica fue significativo (p<0,010). Sin embargo, el modelo probit bivariado revela que el efecto marginal de la consulta farmacéutica en la adherencia a la medicación fue significativamente mayor que en probit de una ecuación. El efecto se incrementó del 7% al 30% (p<0,010) después de controlar el sesgo de endogenicidad. Conclusión: Después del adecuado ajuste del sesgo de endogenicidad, los pacientes satisfechos con los servicios de sus farmacias tiene sustancialmente más probabilidad de cumplir su medicación. Los result, * There are limited studies on quantifying the impact of patient satisfaction with pharmacist consultation on patient medication adherence. Objectives: The objective of this study is to evaluate the effect of patient satisfaction with pharmacist consultation services on medication adherence in a large managed care organization. Methods: We analyzed data from a patient satisfaction survey of 6,916 patients who had used pharmacist consultation services in Kaiser Permanente Southern California from 1993 to 1996. We compared treating patient satisfaction as exogenous, in a single-equation probit model, with a bivariate probit model where patient satisfaction was treated as endogenous. Different sets of instrumental variables were employed, including measures of patients' emotional well-being and patients' propensity to fill their prescriptions at a non-Kaiser Permanente (KP) pharmacy. The Smith- Blundell test was used to test whether patient satisfaction was endogenous. Over-identification tests were used to test the validity of the instrumental variables. The Staiger-Stock weak instrument test was used to evaluate the explanatory power of the instrumental variables. Results: All tests indicated that the instrumental variables method was valid and the instrumental variables used have significant explanatory power. The single equation probit model indicated that the effect of patient satisfaction with pharmacist consultation was significant (p<0.010). However, the bivariate probit models revealed that the marginal effect of pharmacist consultation on medication adherence was significantly greater than the single equation probit. The effect increased from 7% to 30% (p<0.010) after controlling for endogeneity bias. Conclusion: After appropriate adjustment for endogeneity bias, patients satisfied with their pharmacy services are substantially more likely to adhere to their medication. The results have important policy implications given the increasing focus on the r
- Published
- 2008
45. Adherence to treatment: what is done in Sweden? Practice, education and research.
- Abstract
Objective: The objective of this review was to identify the practice, education and research of pharmacists in Sweden in regard to adherence to treatment. Methods: Medline was searched up to the end of February 2008. In addition to the Medline search performed, other available sources were also used to identify relevant articles. Results: No adherence-specific programs have been implemented in Swedish pharmacies. No adherence-specific courses are provided in Swedish Universities educating pharmacists. The adherencerelated research has so far mainly focused on refill non-adherence, primary non-adherence and patient reported non-adherence and readiness to treatment. Conclusions: Adherence-related practice and education of pharmacists will probably change due to the deregulation of the pharmacy market that will take place in the near future in Sweden. Research on adherence will need to be strengthened in the sense that it has so far not been guided by adherence-related theoretical frameworks, despite the fact that there are several theories to hand that try to explain adherence., RESUMEN Objetivo: El objetivo de esta revisión fue identificar la práctica, educación e investigación de los farmacéuticos en Suecia en relación a la adherencia al tratamiento. Métodos: Se buscó en Medline a finales de febrero de 2008. Además de la búsqueda en Medline, se utilizaron otras fuentes disponibles para identificar artículos relevantes. Resultados: No se han implantado programas específicos de adherencia en las farmacias suecas. No se han proporcionado cursos específicos en las universidades suecas para educar a los farmacéuticos. La investigación relacionada con adherencia ha estado fundamentalmente centrada en no cumplimiento de las repeticiones de medicamentos, no cumplimiento primario y incumplimiento comunicado por el paciente y disponibilidad al tratamiento. Conclusiones: La práctica y la educación de farmacéuticos relacionadas con la adherencia probablemente cambien debido a la desregulación del mercado farmacéutico que tendrá lugar en Suecia en un futuro cercano. La investigación en adherencia necesitará ser reforzada ya que no se ha basado en marcos teóricos de adherencia cumplimiento, a pesar de que existen varias las teorías que intentan explicar el incumplimiento
- Published
- 2008
46. The effect of patient satisfaction with pharmacist consultation on medication adherence: an instrumental variable approach
- Abstract
RESUMEN Hay pocos estudios que cuantifiquen el impacto de la satisfacción del paciente con la consulta farmacéutica sobre la adherencia a la medicación. Objetivos: El objetivo de este estudio es evaluar el efecto de la satisfacción del paciente con los servicios de consulta farmacéutica sobre la adherencia a la medicación en una gran organización de gestión de cuidados. Métodos: Analizamos datos de un cuestionario de satisfacción de 6.916 pacientes que habían usado consultas farmacéuticas de la Kaiser Permanente Southern California desde 1993 a 1996. Comparamos, tratando la satisfacción del paciente como exógena, en un modelo probit de una ecuación, con un modelo proibit bivariado donde la satisfacción se trató como endógena. Se utilizaron diferentes conjuntos de variables, incluyendo medidas del bienestar emocional de los pacientes y propensión de los pacientes a adquirir sus medicamentos en una farmacia no Kaiser Permanente (KP). Se usó el test Smith-Blundell para probar si la satisfacción del paciente era endógena. Se usaron test de sobre-identificación para probar la validez de las variables instrumentales. El instrumento débil de Staiger- Stock fue utilizado para evaluar el poder explicativo de las variables instrumentales. Resultados: Todos los métodos indicaron que el método de variables instrumentales utilizado tuvo poder explicativo. El modelo probit de una ecuación indicó que el efecto de la satisfacción del paciente con la consulta farmacéutica fue significativo (p<0,010). Sin embargo, el modelo probit bivariado revela que el efecto marginal de la consulta farmacéutica en la adherencia a la medicación fue significativamente mayor que en probit de una ecuación. El efecto se incrementó del 7% al 30% (p<0,010) después de controlar el sesgo de endogenicidad. Conclusión: Después del adecuado ajuste del sesgo de endogenicidad, los pacientes satisfechos con los servicios de sus farmacias tiene sustancialmente más probabilidad de cumplir su medicación. Los result, * There are limited studies on quantifying the impact of patient satisfaction with pharmacist consultation on patient medication adherence. Objectives: The objective of this study is to evaluate the effect of patient satisfaction with pharmacist consultation services on medication adherence in a large managed care organization. Methods: We analyzed data from a patient satisfaction survey of 6,916 patients who had used pharmacist consultation services in Kaiser Permanente Southern California from 1993 to 1996. We compared treating patient satisfaction as exogenous, in a single-equation probit model, with a bivariate probit model where patient satisfaction was treated as endogenous. Different sets of instrumental variables were employed, including measures of patients' emotional well-being and patients' propensity to fill their prescriptions at a non-Kaiser Permanente (KP) pharmacy. The Smith- Blundell test was used to test whether patient satisfaction was endogenous. Over-identification tests were used to test the validity of the instrumental variables. The Staiger-Stock weak instrument test was used to evaluate the explanatory power of the instrumental variables. Results: All tests indicated that the instrumental variables method was valid and the instrumental variables used have significant explanatory power. The single equation probit model indicated that the effect of patient satisfaction with pharmacist consultation was significant (p<0.010). However, the bivariate probit models revealed that the marginal effect of pharmacist consultation on medication adherence was significantly greater than the single equation probit. The effect increased from 7% to 30% (p<0.010) after controlling for endogeneity bias. Conclusion: After appropriate adjustment for endogeneity bias, patients satisfied with their pharmacy services are substantially more likely to adhere to their medication. The results have important policy implications given the increasing focus on the r
- Published
- 2008
47. Patient perspectives on triggers, adherence to medical recommendations, and disease control in atopic dermatitis: the DATOP study.
- Author
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Ortiz de Frutos FJ, Torrelo A, de Lucas R, González MA, Alomar A, Vera Á, Ros S, Mora AM, and Cuervo J
- Subjects
- Adolescent, Adult, Attitude to Health, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Male, Severity of Illness Index, Young Adult, Dermatitis, Atopic etiology, Dermatitis, Atopic therapy, Patient Compliance, Quality of Life
- Abstract
Introduction and Objectives: To analyze the triggers of atopic dermatitis (AD), adherence to medical recommendations, disease control, and health-related quality of life (HRQOL) from the patient's perspective., Patients and Methods: This was a multicenter, cross-sectional, epidemiological study with the participation of adults (age >16 years; n=125) and children (age, 2-15 years, n=116). Patients had a history of at least 12 months of moderate to severe AD with a moderate to severe flare (Investigator Global Assessment score>2) at the time of recruitment. The Mann-Whitney U test was used to evaluate relationships between disease severity, determined according to the Scoring in Atopic Dermatitis index, and triggers reported by patients, adherence to recommendations and pharmacological therapy, HRQOL, and patient-perceived control., Results: The most common triggers were cosmetic products, clothing, mites, detergents/soaps, and changes in temperature. In 47.2% of adults and 39.7% of children, pharmacological therapy was not initiated at flare onset. Adherence was highest to pharmacological therapy, skin moisturizing, and medical care recommendations. Disease control was considered insufficient by 41.6% of adults and 27. 6% of pediatric patients and, in adults, this was associated with the severity of AD (P=.014)., Conclusions: The therapeutic control of AD is susceptible to improvement, especially in adults. Although patients state that they follow medical recommendations, a significant percentage of patients do not apply recommended treatments correctly. Better education about the disease and its management would appear to be necessary to improve disease control and HRQOL., (Copyright © 2013 Elsevier España, S.L. and AEDV. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
48. ¿Podemos ayudar a nuestros pacientes a dejar de fumar?: la experiencia del Programa de Abandono del Tabaco
- Author
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Gonzalo Grandes, Arantza Arrazola, and Josep M Cortada
- Subjects
Nicotine replacement therapy ,Clinical protocols ,Public Health, Environmental and Occupational Health ,Deshabituación con nicotina ,Health care ,Atención Primaria ,Quality indicators ,Patient compliance ,Effectiveness ,Smoking cessation ,Programa para dejar de fumar ,Outcome and process assessment health care ,Cumplimiento del paciente ,Efectividad ,Protocolos clínicos ,Evaluación de procesos y resultados ,Primary health care - Abstract
ResumenObjetivoDescribir el proceso y resultados al año del Programa de Abandono del Tabaco, para responder a la siguiente pregunta: «¿Justifica la falta de tiempo y recursos la escasa intervención de los médicos sobre el tabaquismo?».MétodosSerie de casos prospectiva formada por todos los fumadores (1.203) que acudieron durante un año por cualquier motivo a la consulta de siete médicos de familia. Se describe el comportamiento de los fumadores ante el programa y las cargas de trabajo que genera. Se consideró que habían abandonado el tabaco aquellos que estaban sin fumar a los 2 años de su captación de forma validada y mantenida durante al menos 12 meses.ResultadosDejaron de fumar el 7,3% de todos los fumadores (intervalo de confianza [IC] del 95%: 5,9-8,9). La captación incrementó el tiempo de consulta en 23 s y descendió desde un promedio de 30 nuevos fumadores al mes por consulta durante los tres primeros meses hasta 12 al final del primer año. Todos fueron aconsejados (incremento promedio de 3 min y 33 s) pero sólo un 17,5% realizó el plan terapéutico durante el primer año (IC del 95%: 15,4-19,9), que tuvo una duración promedio de 72 min y 11 s, y generó una media de 6 citas programadas al mes por consulta. El 20% de los que realizaron dicho plan lograron dejar de fumar (IC del 95%: 14,8- 26,1).ConclusionesLa identificación y el consejo universal a los fumadores, junto con el tratamiento de los motivados, logra importantes éxitos sin incrementar excesivamente las cargas de trabajo habituales.SummaryObjetiveTo describe the process and results of the «Smoking Cessation Program» in order to answer this question: Does the lack of time and resources justify poor involvement of physicians in helping patients to stop smoking?MethodsProspective series of cases that included all smokers (n = 1203) who for any reason attended seven general practices over a period of one year. The behaviour of smokers when the program was offered as well as the workload generated by the implementation of the process are described. Subjects who stopped smoking were those who did not smoke two years after enrolment in a sustained and validated form for least 12 months.ResultsA total of 7.3% of all smokers quit (95% confidence interval [CI]: 5.9-8.9). Enrolment of subjects caused an increase in the consultation time of 23 seconds and decreased from a mean of 30 new smokers per month per practice during the first three months to 12 at the end of the first year. All received advise to stop smoking (mean increase of 3 min and 33 s) but only 17.5% accepted the therapeutic plan during the first year (95% CI: 15.4-19.9) that had a duration of 72:11 min and generated a mean of six programmed appointments a month in each practice. Twenty percent of subjects who participated in the therapeutic plan stopped smoking (95% CI: 14.8-26.1).ConclusionsIdentification and universal advice to smokers, together with treatment of those who are motivated to quit, achieved important success rates without increasing excessively ordinary work loads.
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49. Métodos para la medición de la adherencia a medicamentos modificadores de la enfermedad orales en artritis reumatoide y factores asociados con baja adherencia farmacológica
- Abstract
Objetivos Revisar definiciones, factores asociados a adherencia, métodos para medición y determinación de adherencia a medicamentos modificadores de la enfermedad orales en artritis reumatoide. Métodos Se realizó una búsqueda de la literatura en las bases de datos de Pubmed hasta diciembre de 2017 mediante términos MeSH (((«Arthritis, Rheumatoid» [Mesh] AND «Medication Adherence» [Mesh]) OR «Patient Compliance» [Mesh]) AND «Antirheumatic Agents» [Mesh]) de artículos que estuvieran en idioma español o inglés e incluyeran solo población adulta. Resultados De un total de 387 artículos encontrados, 43 se incluyeron para la revisión general, con información sobre definiciones de adherencia, cumplimiento, concordancia y persistencia, componentes, clasificación y dimensiones, factores de riesgo relacionados con la no adherencia al tratamiento, descripción de los métodos de medición. Solo 9 artículos midieron adherencia e incluyeron información sobre factores relacionados con adherencia a medicamentos orales en artritis reumatoide. Conclusiones La adherencia al tratamiento farmacológico en artritis reumatoide es subóptima y se relaciona con menor efectividad en el control de la actividad inflamatoria. Los principales factores relacionados con baja adherencia incluyen problemas de acceso y disponibilidad del medicamento, mayor actividad y duración de la enfermedad, polifarmacia, uso de medicamentos por periodos prolongados, bajo estrato socioeconómico, etnia, reacciones adversas por medicamentos, percepción de inefectividad de la medicación y enfermedades concomitantes. Es necesario incorporar de forma sistemática la medición de adherencia farmacológica dentro de la práctica clínica rutinaria y la identificación de los factores de riesgo más frecuentes asociados a una baja adherencia con el fin de diseñar estrategias encaminadas a mejorar la adherencia de los pacientes y lograr mejores desenlaces clínicos.
50. Validación y calibración al español del cuestionario CQR (Compliance Questionnaire on Rheumatology) para la medición de adherencia a la terapia antirreumática en un grupo de pacientes colombianos con artritis reumatoide
- Abstract
Introducción: La adherencia al tratamiento es uno de los pilares para lograr el control de cualquier enfermedad, y esto aplica también en la artritis reumatoide. Existen diferentes formas de evaluar el grado de adherencia, siendo las escalas de medición uno de los métodos más usados por su facilidad en aplicación y bajo costo. El objetivo de este estudio fue traducir y validar el Compliance Questionnaire on Rheumatology (CQR) al español y calibrar los puntajes de acuerdo con la actividad de la enfermedad medida mediante DAS-28. Materiales y métodos En la primera fase del estudio se llevó a cabo el proceso de traducción empleando las guías para la traducción y adaptación cultural de medidas centradas en pacientes. Posteriormente se realizó un proceso de aclaración cognoscitiva. Finalmente se llevó a cabo un estudio de pruebas diagnósticas para determinar el mejor punto de corte para el puntaje de la escala CQR en la identificación del nivel de adherencia al tratamiento antirreumático en pacientes con artritis reumatoide, empleando el DAS 28 como subrogado de adherencia. Resultados: un total de 233 pacientes con edad promedio de 46,3 (±13,9) años y tiempo promedio de evolución de enfermedad de 11,2 (±9,6) años. El punto de corte del CQR para establecer adherencia al tratamiento fue de 80,7, con lo cual se obtuvo una sensibilidad del 80,2% (IC95%: 71,9-86,9%) y una especificidad del 72,3% (IC95%: 63,1-80,4%). Con este punto de corte se estableció que el 43,8% (n=102) de los pacientes eran adherentes a la terapia antirreumática oral. Conclusión: se desarrolló una versión en español del CQR y se calibraron los puntos de corte obteniendo una herramienta práctica y de rápida aplicación clínica, con aceptables sensibilidad y especificidad.
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