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Disruptions often call for rapid innovation at scale. Open innovation (OI) is critical in such contexts because it allows organizations to access resources beyond the firm's boundaries. Yet, many OI projects fail, posing significant risks during disruptions. This article examines 12 ventilator development projects during the COVID-19 pandemic, of which only seven succeeded. Fifty-five interviews were analyzed to understand how organizational roles influence the outcomes of OI projects in times of disruption. The key finding is that projects that succeeded involved an organizational role largely absent in those that failed: namely, a catalyst. [ABSTRACT FROM AUTHOR]

Service-oriented manufacturing has been a prevalent trend in integrating product collaborative development with maintenance service, whereas the final products are frequently trapped into severe quality defects lacking appropriate contracting incentives. This paper establishes a tractable framework investigating the alignment of inspection and warranty strategies to manage product quality throughout the R&D, manufacturing and usage processes. Specifically, the manufacturing effort is motivated by a cost-sharing contract provided by the researcher, who performs quality inspection upon receiving the final product. Subsequent maintenance service is predesignated for warranty period coverage that the cost is partially claimed for compensation from the manufacturer. Under both breakdown and preventive maintenance strategies, we elaborate and compare the optimal incentive intensities solving the equilibrium effort decisions and inspection accuracy. The results suggest that both R&D and manufacturing effort levels under preventive maintenance are slightly higher than that under breakdown maintenance scenario, while inspection accuracy contradicts conversely. The breakdown maintenance strategy is associated with a lower proportion of warranty costs borne by the manufacturer. For a sufficient long warranty period, the researcher is better off to conduct preventive maintenance periodically. Our study contributes to providing explicit implications to manage product development quality with adequate inspection and warranty strategies. [ABSTRACT FROM AUTHOR]

We examine how short product life cycle lengths constrain real activities management among a group of manufacturing firms. Companies with short-cycle products face fast product obsolescence and constant pressure to develop and market new products. Fast product obsolescence increases the cost of overproduction, while constant pressure for new product development increases the cost of opportunistic spending cuts. We predict and find evidence that in general, short-cycle firms do not beat earnings thresholds through overproduction and discretionary spending cuts as extensively as long-cycle firms do. However, since the Sarbanes-Oxley Act came into effect, short-cycle firms have increasingly overproduced, and there is no longer a difference in overproduction between short- and long-cycle firms. Moreover, the presence of major customers attenuates the relationship between product life cycle lengths and real activities management, while a large market share and high fixed-assets intensity both accentuate the relationship. Finally, short-cycle firms are also less likely to use LIFO (last-in, first out) liquidation to inflate earnings than long-cycle firms. [ABSTRACT FROM AUTHOR]

To deal with the growing amount of e-waste propelled by introduction of new products, increasing governments are considering amending take-back regulations to impose more stringent collection targets. Motivated by this trend, this study focuses on the reuse policy for e-waste with three factors: product innovation degrees, collection targets, and reuse decisions. We first confirm the traditional wisdom that a higher innovation degree often results in a higher profitability but hurts the environment. As such, we agree with the suggestion that the environmental agencies need to impose more stringent collection targets to deal with the growing amount of e-waste propelled by new product introduction. Moreover, our analysis further indicates that the more stringent collection target results in an inverted U-shaped curve for profitability and lower environmental impact. Therefore, besides confirming the intuitive expectation, we also add a word of caution on the recast of WEEE Direct: although tightening the overall collection target for the OEM is a powerful tool, we still call for the governments and environmental agencies, rather proceeding from the entire industry, should amend take-back regulations to set detailed collection targets based on the specific products characterised by the rate of innovation. [ABSTRACT FROM AUTHOR]

Retaining talented salespeople is crucial for a company's survival. One effective strategy for retaining employees is to actively involve them in significant business decisions. Salespeople, however, differ significantly from their colleagues, for example, they are typically highly customer-oriented. Therefore, integrating them into new product development (NPD) may be a potentially valuable approach for firms to retain them. Nonetheless, salesforce integration (SI) into NPD is more intricate than initially thought. It may involve both psychological SI benefits (such as feeling valued or competent) and costs (including potential conflicts with NPD team members or role conflicts), thus differently affecting a salesperson's willingness to stay with the firm. To learn more about the intriguing link between SI into NPD and salesperson retention, we conducted a qualitative study and applied grounded theory to conceptualize this relationship. We identify key mediators (psychological SI benefits and costs) and moderators (such as company, NPD team, salesperson, procedural, relationship, or product characteristics) that can influence the SI-into-NPD-salesperson-retention connection and develop related, relevant propositions. All of these insights are integrated into a cohesive framework and we present a research agenda to guide future exploration of this critical subject. Furthermore, we derive and discuss implications for both academics and practitioners. [ABSTRACT FROM AUTHOR]

We study how patenting enhances customer capital and creates financial value in a product market characterized by information asymmetry between firm insiders and customers. We find that firms with more and higher quality patents develop greater customer capital, as measured by more positive customer perceptions of product novelty and quality. To establish causality, we exploit the exogenous variation in the random assignment of patent examiners to review applications and use the average examiner leniency as an instrument for patent grants. Our mediation analysis documents a positive impact of patenting on firm performance and financial market valuation through enhanced customer capital. [ABSTRACT FROM AUTHOR]

The increasing complexity of industrial systems demands more effective and intelligent maintenance approaches to address manufacturing defects arising from faults in multiple asset modules. Traditional digital twin (DT) systems, however, face limitations in interoperability, knowledge sharing, and causal inference. As such, cognitive digital twins (CDTs) can add value by managing a collaborative web of interconnected systems, facilitating advanced cross-domain analysis and dynamic context considerations. This paper introduces a CDT system that leverages industrial knowledge graphs (iKGs) to support maintenance planning and operations. By employing a design structure matrix (DSM) to model dependencies and relationships, a semantic translation approach maps the knowledge into a graph-based representation for reasoning and analysis. An automatic solution generation mechanism, utilising graph sequencing with Louvain and PageRank algorithms, derives feasible solutions, which can be validated via simulation to minimise production disruption impacts. The CDT system can also identify potential disruptions in new product designs, thus enabling preventive actions to be taken. A case study featuring a print production manufacturing line illustrates the CDT system's capabilities in causal inference and solution explainability. The study concludes with a discussion of limitations and future directions, providing valuable guidelines for manufacturers aiming to enhance reactive and predictive maintenance strategies. [ABSTRACT FROM AUTHOR]

Creative ads are applied widely in new product marketing. The present research explores the impact of creative ads (divergent vs. relevant ads) on purchase intention for really new products and incrementally new products. A series of studies concludes that (1) divergent ads are more effective for promoting incrementally new products, (2) relevant ads are more effective for promoting really new products, (3) self-referencing mediates the joint effect of creative ads and product newness on purchase intention, and (4) there is an inverted U-shaped relationship between self-referencing and purchase intention for new products. Theoretically, the authors argue that a moderate amount of self-referencing is particularly desirable—that is, there is a "Goldilocks region" that produces an optimal level of persuasion. They provide guidance to creative ad managers to help them reach the "Goldilocks region" when advertising new products. [ABSTRACT FROM AUTHOR]

We build a novel comprehensive data set of new product trademarks as an output measure of product development innovation. We show that risk-taking incentives in CEO compensation motivate this type of innovation and that this innovation improves firm performance. Using an exogenous shock to executive compensation, we find that reductions in stock option compensation cause reductions in new product development. We also find that firms undertaking new product development experience increases in future cash flow from operations and return on assets. These findings suggest the importance of product development innovation to firms and new trademarks as a novel innovation measure. [ABSTRACT FROM AUTHOR]

In this research, the authors examine how consumers perceive the fruits of university–industry collaborations (i.e., new products codeveloped with universities). Eight studies document a positive university effect and highlight its practical significance and boundary conditions. An Instagram A/B test utilizing a video that refers (vs. does not refer) to the underlying university–industry collaboration results in higher click-through rates and ad engagement levels. Another field study demonstrates that university-codeveloped products are more attractive to consumers, even after an actual product trial. Further, several consequential studies reveal that consumers are willing to pay up to 65% more for products marketed as codeveloped with a university. The authors argue and show that collaborating with a university infuses the underlying firm with a stronger sense of scientific legitimacy, thereby making the resulting product more attractive to consumers. Congruously, the authors find that the effect is more pronounced when the scientific legitimacy engendered by universities is more important to the focal product (i.e., high tech vs. low tech), underlying company (i.e., new vs. established), or target customer (i.e., high vs. low belief in science). [ABSTRACT FROM AUTHOR]

Two organizations that focus on tech-based health innovation have partnered to improve the mental health of young adults. In this "tech for good" project, Hopelab and Grit Digital Health worked together to create an app using human-centered product design. With the core needs of users at the forefront, the team developed an app both with and for college students to combat loneliness, a prevalent issue that can lead to other problems such as depression, anxiety, and even dropping out of college. The team also applied systems thinking to address the root causes of this "wicked problem," resulting in their Nod app, which has improved outcomes for college students. This article is based on the author's award-winning case study. [ABSTRACT FROM AUTHOR]

How does the viability of a product category shift over time? Studies abound on how categories emerge and become established, or fall out of use. Yet, extant research has often examined the evolution of categories one at a time, leaving open the question of how related categories affect a focal category's viability. In contrast, we consider both intra- and inter-category dynamics. Viewing categories as continuously shaped by actors' efforts to position their products, we argue that these efforts alter the coherence that products exhibit not only within a category (a category's heterogeneity), but also across related categories (a category's distinctiveness). We theorize how the interaction between a category's heterogeneity and distinctiveness shapes its subsequent viability. When a focal category's distinctiveness is low, the heterogeneity–viability relationship takes an inverted U-shape. However, as distinctiveness grows, the relationship flattens and eventually flips to a U-shape. We explain this by considering the trade-off between the "classification" and "valuation" benefits that a category affords. We find support for our argument by tracking 170 categories over an 11-year period on Kickstarter, one of the largest crowdfunding platforms. By providing a nuanced understanding of category dynamics, we shed new light onto the fluctuating viability of categories. [ABSTRACT FROM AUTHOR]

Research on the tension between exploration and exploitation has made fundamental contributions to our understanding of firm growth via entry into new businesses. While there is consensus about the merits of balancing exploration and exploitation, there has been debate about the best means for achieving balance. In our prior analysis of firms' choices between acquisition and internal development as entry modes, we found that the role of acquisitions tends to differ inside versus outside a firm's primary business domain: firms use within-domain acquisitions largely for exploitation, while out-of-domain acquisitions support exploration. To examine these issues in greater depth, we focus here on the historical use of acquisition versus internal development by two major technology firms, Amazon and Alphabet. We show that the two firms have been remarkably different in their use of acquisitions versus internal development. Consistent with our prior analysis, Amazon has emphasized internal development but has used acquisitions to strengthen its existing businesses and to enter new products and services that were (initially) outside Amazon's primary business domain. In contrast, Alphabet has relied heavily on acquisitions to enter new businesses within its primary domain but has emphasized internal development of "moonshot" businesses outside this domain. These differences illuminate the use of acquisitions in market entry and make clear that there is no single right way to utilize acquisition versus internal development in the pursuit of balance between exploration and exploitation. [ABSTRACT FROM AUTHOR]

Does proprietary knowledge protection (PKP) spur or hinder the product-market performance of new firms? Exploiting the staggered adoptions of the inevitable disclosure doctrine by U.S. State Courts, which enhance PKP, we show that treated firms increase industry-adjusted sales growth by 2% compared to control firms. The effect is concentrated among small and young firms and increases with the scope of proprietary knowledge and rivals' access to external finance. PKP encourages firms to develop new products and stimulates initial public offering activity. Our results suggest that PKP alleviates predation risk associated with "deep-pocket" rivals by allowing firms to maintain competitive advantages. [ABSTRACT FROM AUTHOR]

The key to radical innovation lies in technological breakthroughs, and the key to technical breakthroughs lies in the application of cross-domain knowledge. However, in the conceptual design stage of new product development, the designer's cognition and knowledge are limited and the retrieval and evaluation of cross-domain technologies is often subjective, making it difficult to generate radical concepts. To address the above issues, this paper proposes a method for cross-domain technology recommendation based on patent analysis. In this method, feature words in various domains of patents are used to generalise the abstract functions of product core subsystems, where designers can obtain more comprehensive cross-domain technologies. This is conducive to breaking the design fixation of designers. Subject–Action–Object structural and functional similarity are combined to quickly extract cross-domain technologies in patents. Then multiple technical indicators are used to objectively evaluate and rank cross-domain technologies. This approach helps designers objectively select cross-domain technologies to change the way next-generation products work, enabling early planning of production conditions and a head start in the market. The method has been verified in a new product development project on peeling equipment, a new product that meets radical indicators is finally obtained. [ABSTRACT FROM AUTHOR]

After decades, dialogues on human resource management (HRM), intellectual capital (IC), and ambidexterity still continue, mirroring that the role of ambidextrous capability in translating the impact of HRM into superior performance remains unclarified. At this juncture, the current study proposes a novel theoretical framework to extend research on the relationship between IC‐enhancing HR practices and innovation. It is done sophisticatedly by examining how firm exploitative and exploratory capabilities mediate the relationship between different combinations of HR configurations and firm innovation. To this end, we designed rigorous time‐lagged research with three waves of data collection from the Iranian healthcare sector. Our analyses revealed that firm explorative and exploitative capabilities significantly mediate the relationship between human, social, and organizational capital‐enhancing HR configurations and firm innovation. More conspicuously, by unraveling interaction patterns among distinct HR configurations, our study revealed the intricacies of the functioning of IC‐enhancing HR practices in fueling firm ambidexterity. Hence, our study offers design options to navigate through exploitation and exploration in light of the firm's core innovation strategy. We discuss the theoretical and practical implications of our findings and suggest future research avenues. [ABSTRACT FROM AUTHOR]

Despite the growing diversity of customer needs, little empirical evidence would guide managers to leverage customer need diversity (CND) for radical innovation. Building on the knowledge-based view and dynamic capabilities, the authors explore relationships among CND, strategic flexibility, big data analytics capabilities, and radical innovation performance. With 308 survey responses from innovation managers, the authors find that CND impacts radical innovation performance via (1) mediation through strategic flexibility and (2) moderation by volume, variety, and velocity capabilities associated with big data analytics. The moderation effects of volume and velocity capabilities are positive and negative simultaneously, depending on the purpose for which CND is utilised. Therefore, to leverage customer need diversity, firms need to build strategic flexibility and exercise caution when utilising big data analytics capabilities. [ABSTRACT FROM AUTHOR]

Knowledge sharing is considered an important promotor of new product development (NPD) performance. However, studies have shown that making experts share knowledge in new product development (NPD) projects is often a challenging task. Consequently, this topic has attracted substantial attention in academic research. However, although studies have produced valuable insights, more detailed accounts of the mechanisms shaping knowledge sharing processes in NPD projects are sparse. To add to the knowledge on this topic, this study conducts a series of interviews with NPD professionals at manufacturers of high-tech industrial products to identify 'factors influencing knowledge sharing' (FIKS). The identified FIKS are explained through the socio-physiological theory, the 'reasoned action approach' (RAA). This involves several contributions. First, the study provides a detailed explanation of the role of FIKS by describing how they affect the behaviour of knowledge providers and receivers in NPD processes. Second, by identifying 161 FIKS in NPD processes, organised under 18 categories, the study offers the so far most extensive account of FIKS in NPD processes. Third, the findings suggest a special characteristic of knowledge sharing in NPD contexts concerning the relatively high importance of knowledge receiver behaviour. [ABSTRACT FROM AUTHOR]

Product configuration design combines the existing configurable components of enterprises to quickly form a new product that meets customised requirements. However, the representation, maintenance, and update of the configuration knowledge, and the mismatch problem restrict the rationality and efficiency of existing configuration design methods. In this paper, a recommendation model is developed for customised product configuration design, which takes personalised customer requirements and product component information as input and outputs a ranked list of component instances. It consists of two sub-models: a retrieval sub-model and a ranking sub-model. The retrieval sub-model selects a set of component instance candidates from all possible candidates, and then the ranking sub-model ranks them and selects the best possible candidate. To boost the ranking sub-model performance, we propose a novel interacting network, DualAdap, to extract meaningful low-order, high-order, and adaptive-order cross features. Based on learned cross features, the ranking sub-model computes the adoption scores of all candidates and then selects the best possible candidate according to adoption scores. The configuration design of the elevator traction machine is taken as a case study. Results verify that our recommendation model can identify similar component instances and then accurately pick out the best possible candidate that meets customer requirements. [ABSTRACT FROM AUTHOR]

Platform-based product development is a cost-efficient approach to satisfy wide range of customer preferences. One important problem is the product platform configuration, in which two types of platform configuration are widely used, either module selection or module integration. The platform configuration based on module selection provides a broader solution space of platform selection, while module integration facilitates product platform commonality to gain economic benefits. Up to date, most research focused on the platform configuration based on module selection with a given module set. In this paper, we propose a new model to determine the optimal platform configuration for an external product family, considering both module selection and integration. The demand for the external product family is uncertain and assumed to follow normal distribution. A hybrid methodology combining simulated annealing and variable neighbourhood search is proposed. A numerical examination is carried out for the purpose of evaluation. The results show that the proposed model can provide a practically good solution. Main contributions of this research are two folds, one is the balance point between module selection and module integration in the platform configuration and the other is that we take into account the operation cost of module acquisition to the platform configuration problem. [ABSTRACT FROM AUTHOR]

Research Summary: This research addresses the tension of audiences often rejecting creative products despite creativity being foundational to organizational success. To better understand this issue, we take an abductive approach to disentangle the effects of creative content (how creative the core concept is) and creative packaging (how creatively the core concept is presented and visualized) while accounting for audiences' different expertise levels. Across two archival studies and a pre‐registered experiment, we find that both experts and general audiences react positively to creative content. However, reactions to creative packaging display greater variability: on average, experts react positively whereas general audiences react negatively. We find no interaction between the two variables. We discuss the theoretical implications of these findings for the literature. Managerial Summary: While creativity is foundational to organizational success, audiences often reject creative products. Across two archival studies and an experiment, we show how the effect of creativity on different audience's reception can be better understood when disentangling creative content (how creative the core concept is) from creative packaging (how creatively the core concept is presented and visualized). Our results suggest that companies should (a) invest more resources in developing products high in creative content—products that break current norms and are different from others—and (b) acknowledge that heavy investments into novel and visually groundbreaking packaging lend diminishing returns, particularly for general audiences: for the same level of quality a traditional (vs. creative) packaging yields more advantages. [ABSTRACT FROM AUTHOR]

Cicer arietinum or chickpea is an important and highly nutritious pulse, a source of complex carbohydrates, proteins, vitamins, and minerals, considered non-allergenic, and non-GMO crop. Processing technologies play an important role in modifying some chickpea properties and thus increasing its nutritional and health benefits. Herein is summarized and compared the available data on nutritional and functional aspects caused by thermal, nonthermal, and combinations of treatments for chickpea processing. The study focuses on describing the processing conditions necessary to change chickpea matrices aiming to enhance compound bioavailability, reduce anti-nutritional factors and modify functional characteristics for industrial application in product development. Thermal and nonthermal treatments can modify nutrient composition and bioavailability in chickpea matrices. Thermal treatments, moist or dry, prevent microbial spoilage, increase product palatability and increase protein quality. Nonthermal treatments aim to shorten the processing time and use less energy and water sources. Compared to thermal treatments, they usually preserve organoleptic attributes and bioactive compounds in chickpea matrices. Some treatment combinations can increase the efficacy of single treatments. Combined treatments increase antioxidant concentration, protein digestibility and available starch contents. Finally, despite differences among their effects, single and combined treatments can improve the nutritional and physicochemical properties of chickpea matrices. [ABSTRACT FROM AUTHOR]

Purpose: This paper aims to investigate sustainability-led innovation, focusing on the interplay between product and process innovation for sustainability goals and the underlying supplier–customer relationships. Thus, the paper delves into sustainability-led innovation and how it affects supplier–customer relationships, and vice versa, thus providing a twofold perspective. Design/methodology/approach: The textile industry is the empirical context of this study, which is exploratory research based on in-depth, semi-structured interviews with entrepreneurs, managers and experts in the textile industry. Findings: In the textile industry, sustainability-led product innovation concerns mainly product durability and performance, product recyclability and the use of waste for new product development. Process innovation deals with circular economy, traceability and water and chemical use minimization. The paper also shows how sustainability-led innovation is implemented in more technical terms and regarding supplier–customer relationships. Originality/value: The paper adopts an original perspective on how processes take place in the relationships between suppliers and customers, where there is no dominance of one actor, but innovation emerges from interdependence and interaction. Such perspective allows to provide an in-depth analysis of the supplier–customer relationships and underlying dynamics that affect sustainability-led innovation; moreover, the authors study how such innovation impacts supplier–customer relationships and the underlying relational dynamics. The value of the paper also stands in delivering a real representation of the innovation processes grounded in the textile industry. [ABSTRACT FROM AUTHOR]

The carrot is a root vegetable well-known for its high nutritional content and health advantages. It is well known for its strong antioxidant content, particularly carotenoids, which have been linked to cancer-fighting effects. Carotenoids, polyphenols, and vitamins in carrots have been demonstrated to have anticarcinogenic, antioxidant, and immune-boosting qualities, lending credence to the long-held concept that carrots are good for eye health. Numerous in-vivo and in-vitro research have revealed carrots' numerous health benefits, including cholesterol-lowering, anti-diabetic, anti-hypertensive, renoprotective, hepatoprotective, and facilitate the excretion of fats and bile by the liver. Carrot seed extracts have also been shown to have antibacterial, antifungal, anti-inflammatory, cardioprotective, and hepatoprotective effects. Carrot pomace, which contains about 50% -carotene, has been recognized as a valuable byproduct that can be economically helpful for boosting culinary products such as biscuits, bread, and cakes, as well as preparing various functional goods. Carrot pomace powder is used to create bread and extruded items, demonstrating this waste's variety and prospective applications. This comprehensive review focuses on the nutritional composition, phytonutrients, functional properties, product development, and utilization of carrots and their byproducts. This review aims to provide valuable insights into the diverse uses and advantages of incorporating carrots into various food and health products by highlighting the potential health benefits and applications of carrots and their derivatives. [ABSTRACT FROM AUTHOR]

Cashew (Anacardium occidentale L.) plays an important role in global agriculture, particularly in commercializing the cashew kernel. Nevertheless, kernel extraction poses a challenge due to the nut variable shape and size. Characterizing the properties of the cashew nut becomes a pivotal input for the advancement of processes and machinery. This work presents a comprehensive characterization of raw and steamed cashew nuts from Puerto Carreño, Colombia, with focus on morphological, physical, and mechanical properties. Cashew nut samples from different farms in the region were collected. Morphological properties, including size and shape, were analyzed by measuring length, width, and thickness for 100 nuts from each supplier, both in their raw state and after steaming. Geometric diameter and sphericity were calculated, and qualitative shape characterization was performed. Physical properties, such as mass, bulk density, true density, and moisture content, were also measured. Angle of repose and coefficient of friction were determined to assess flow and frictional behavior. Additionally, compressive mechanical properties were evaluated through uniaxial compression testing along three orientations. The findings indicated significant differences in morphological and mechanical properties between raw and steamed cashew nuts. Conversely, the results demonstrated that cashew nuts from Vichada region exhibit a noteworthy degree of dispersion and larger dimensions than those from Asia and Africa, comparable to those from Brazil. The findings guide machinery design in the cashew industry and offer insights into the physical, morphological, and mechanical properties of cashew nuts in Puerto Carreño, contributing to understanding and enabling quality assessment, processing optimization, and product development. [ABSTRACT FROM AUTHOR]

Rapid changes in customer needs (CNs) and technology force businesses to develop new products to compete. Functional requirements (FRs) and non-functional requirements (NFRs) are created when CNs are correctly interpreted. FRs specify what the product must do, whereas NFRs specify how a system must behave. The study presents a comprehensive framework that helps product developers accurately and quickly extract the essential NFRs. This is because there is still no agreement in the requirements engineering community regarding which NFRs should be elicited for developing a system and how they should be applied and documented. Moreover, the majority of research in this area has either concentrated more on the field of software development or given more attention to applying FRs and less attention to NFRs. The presented framework applies the integrated approaches of QFD, DSM, and hesitant fuzzy sets (HFS). Design for eXcellence is also used to ensure that system quality attributes, such as NFRs, are considered during the development process. The framework was used to develop a solar power system, and the results indicated that the primary NFRs essential for system development are availability, reliability, maintainability, modularity, flexibility, and extensibility. [ABSTRACT FROM AUTHOR]

The need for consistency in analytical method development reinforces the dependence of pharmaceutical product development and manufacturing on robust analytical data. The Analytical Quality by Design (AQbD), akin to the product Quality by Design (QbD) endows a high degree of confidence to the method quality developed. AQbD involves the definition of the analytical target profile as starting point, followed by the identification of critical method variables and critical analytical attributes, supported on risk assessment and design of experiment tools for the establishment of a method operable design region and control strategy of the method. This systematic approach moves away from reactive troubleshooting to proactive failure reduction. The objective of this review is to highlight the elements of the AQbD framework and provide an overview of their implementation status in various analytical methods used in the pharmaceutical field. These methodologies include but are not limited to, high-performance liquid chromatography, UV-Vis spectrophotometry, capillary electrophoresis, supercritical fluid chromatography, and high-performance thin-layer chromatography. Finally, a critical appraisal is provided to highlight how regulators have encouraged AQbD principles application to boost the prevention of method failures and a better understanding of the method operable design region (MODR) and control strategy, ultimately resulting in cost-effectiveness and regulatory flexibility. [ABSTRACT FROM AUTHOR]

Objectives: This paper aims to develop and validate a taxonomy for the assessment of the subjective experience of curly hair manageability. It represents the latter of two iterative stages of a mixed‐method design interdisciplinary project. Methods: The qualitative stage of the study incorporated thematic analysis of 14 interview transcripts generated using a video‐ethnographic method (SEBE). A survey‐based instrument assessing different elements of the construct of hair manageability designed during the first stage of this project was further developed following consultations with experts with extensive experience in hair research, product development, testing and trichology. The instrument was tested online with 506 female participants self‐reporting natural curly hair, types 3A and higher according to the Andre Walker Curl Classification. Results: The initial construct of four groups of hair goals received positive content validity from the experts. High scale reliability was achieved for the aesthetic, haptic and emotive goals' scales as well as for hair esteem (Cronbach's alpha >0.75). Curl type was the only personal hair attribute that was correlated with hair goals and perceptions. From the demographic and lifestyle data, only age was correlated with goals and willingness to try new products. Common hair practices and product usage were also correlated with hair curl and goals. Conclusion: The appropriateness of the instrument for measuring the strength of different hair goals and perceptions relevant to hair curvature degree and hair esteem has been validated. The instrument will support the development and testing of products better aligned with the manageability needs of very curly and textured hair. It was also confirmed that hair curvature is the most significant determinant of practices, and age of product attitudes. [ABSTRACT FROM AUTHOR]

Usually found bound to other complex molecules (e.g., lignin, hemicellulose), phenolic compounds (PC) are widely present in agro-industrial by-products, and their extraction is challenging. In recent times, research is starting to highlight the bioactive roles played by bound phenolics (BPC) in human health. This review aims at providing a critical update on recent advances in green techniques for the recovery of BPC, focusing on enzymatic-assisted (EAE) and fermentation-assisted extraction (FAE) as well as in the combination of technologies, showing variable yield and features. The present review also summarizes the most recent biological activities attributed to BPC extracts until now. The higher antioxidant activity of BPC—compared to FPC—coupled with their affordable by-product source make them medicinally potent and economically viable, promoting their integral upcycling and generating new revenue streams, business, and employment opportunities. In addition, EAE and FAE can have a biotransformative effect on the PC itself or its moiety, leading to improved extraction outcomes. Moreover, recent research on BPC extracts has reported promising anti-cancer and anti-diabetic activity. Yet further research is needed to elucidate their biological mechanisms and exploit the true potential of their applications in terms of new food products or ingredient development for human consumption. [ABSTRACT FROM AUTHOR]

This paper investigates the coevolution between the development of British constitutional rights and the status of social and minority groups in planning London since its first post-WWII comprehensive plan. The study employed a historical document analysis by scrutinizing major London urban plans, pertinent British legislation, and constitutional rights enactments to uncover the evolution of urban planning amid a changing rights-based constitutional landscape. The study concludes that the status of social and minority groups within London's urban planning is not solely a product of planning approaches but is significantly shaped by the prevailing political and constitutional frameworks regarding minority rights. [ABSTRACT FROM AUTHOR]

This paper aims to determine the distribution of light intensity values in a room at a certain time using a Light Dependent Resistor (LDR) sensor by comparing the light intensity and sensitivity of the LDR in conditions of changing dark to light in the room. The distribution of light intensity is measured using a light sensor assisted by Arduino application, the results of the average light intensity value when changing from dark to light conditions will automate the lights to turn on and off. Thus, it is hoped that it can save electricity. This experiment was integrated with the engineering design process through the following stages: 1) Identification of the problem, 2) Discussion of problemsolving, 3) Designing, 4) Creating, redesigning, and evaluation tests, and 5) Sharing solutions. Indoor light intensity measurements were carried out for 7 days, from 00.00, to once every 3 hours the distribution of the light intensity values read was checked. The research results provide new findings that the average distribution of light when changing from dark to light at 05.36 - 05.37 indoors shows a value of 105-135 lx, while from light to dark at 18.07 - 18.08 shows a value of 75 - 88 lux. These results can be used in further research to determine values that can be input into coding to control LDR sensor automation in product development. [ABSTRACT FROM AUTHOR]

Previous work has found that a small number of export superstars contribute disproportionally to the economy's overall exports. Differently from export superstars, this study is the first to define high growth exporters (HGXs) (that are not export superstars) as a new firm category. We provide their economic importance and depict their micro-level anatomy. By tracking HGXs in Croatia for over a quarter of a century, 44 out of 100 export superstars in 2019 were previously HGXs. HGXs represent only 0.5% of all firms and 18% of high growth firms (HGFs) in the economy, but are responsible for about 25% of new exports and 5% of new jobs. During their growth episode, HGXs hire more employees from technology intensive industries with previous experience in exporting. They often hire on a single year work contract, and more frequently send new employees to work abroad. HGX also increase their presence in more advanced markets, increase the number of new export products and decrease their reliance on the largest product or largest export market. We argue HGXs represent an under-researched category of firms. [ABSTRACT FROM AUTHOR]

Business operations and supporting data analysis initiatives are impeded by the silos of data present within departments, systems, and business units. Consequently, the ability of managers and engineers to harness data for operational management and informed decision-making is curtailed. The rapid advancements in technology have revolutionized various aspects of product development, manufacturing, operations, and end-of-life treatment. One such transformative concept, the digital thread, has emerged as an important paradigm. It orchestrates the integration of information and data along the entire product lifecycle, spanning from initial design and engineering through production, maintenance, use, and eventual end of life. While the digital thread has garnered increasing attention within both the research community and industrial enterprises, there remains a notable lack of standardization concerning its utilization and applications. This comprehensive literature review aims to explore the role of the digital thread in manufacturing within the context of the product lifecycle. As a result, this review synthesizes insights into the technologies, roles, and functions of the digital thread throughout the product lifecycle. Furthermore, it proposes a structured framework designed to impart a standardized perspective of the digital thread's relevance within the manufacturing product lifecycle. Ultimately, this framework is poised to serve as a guiding resource for practitioners and researchers in designing and implementing digital threads. [ABSTRACT FROM AUTHOR]

The priority review voucher was established to incentivize research and development of treatments for traditionally underfunded diseases and was extended to medical countermeasures from 2016 to 2023, despite limited evidence of an association between the voucher program and increased product development. To determine whether the voucher program has incentivized initiation of new medical countermeasures in clinical trials, we created three cohorts of material threats: (i) COVID‐19, (ii) opioid pharmaceutical‐based agents, and (iii) all others. Using the Citeline Trialtrove database, we determined the number of medical countermeasures initiated in clinical trials from 2009–2016 and 2017–2023. Eligibility of COVID‐19 products for the voucher was confirmed with the issuance of a voucher for remdesivir in October 2020, so we compared January 2020–October 2020 to November 2020–July 2023. We fit two Poisson models—before and after voucher creation—within each cohort. Among COVID‐19 medical countermeasures, there was a decrease in the proportion of drugs initiated before (4.5%; 95% CI, 1.0 to 8.3%) vs. after voucher eligibility (−5.1%; 95% CI, −6.1 to −4.0%) (P = 0.01). Among opioid pharmaceutical‐based agents medical countermeasures, the rate of new drugs initiated did not change from 2009–2016 (8.1%, 95% CI, −4.4 to 22.6%) to 2017–2023 (5.6%; 95% CI, −3.2 to 15.2%) (P = 0.82). Among all other medical countermeasures, the rate of new drugs initiated also did not change from 2009–2016 (6.6%; 95% CI, −5.6 to 20.8%) to 2017–2023 (−14.8%; 95% CI, −29.2 to 2.0%) (P = 0.15). The priority review voucher program was not associated with stimulating new clinical testing of investigational medical countermeasures. [ABSTRACT FROM AUTHOR]

Purpose: New product development (NPD) projects are strategically important for firms' operations but suffer from high failure rates. Leadership is a key factor for project success. However, in contrast to positive project leadership, project managers' knowledge hiding has received little attention. Drawing on the input-mediator-output (IMO) framework and model of work team resilience, we explored the effect of project managers' destructive knowledge hiding (i.e. evasive hiding and playing dumb) on project team performance (i.e. efficiency and effectiveness) and the serial indirect effect through team psychological safety and transactive memory systems. Design/methodology/approach: We conducted a time-lagged multiple-sourcing investigation of Chinese high-tech firms and tested the hypotheses using data collected from 105 NPD project teams. Findings: Our findings demonstrated that project managers' knowledge hiding negatively affects NPD project team performance and indirectly negatively affects transactive memory systems through team psychological safety. Moreover, project managers' knowledge hiding exerts a negative indirect effect on team performance through team psychological safety and transactive memory systems in serial. Originality/value: This study contributes to the literature on operations management (OM) by broadening our understanding of the connection between project managers' destructive knowledge hiding and the failure of NPD projects. In providing such insight, it also offers practical guidance for overcoming team-level obstacles arising from project managers' knowledge hiding. [ABSTRACT FROM AUTHOR]

Purpose: This paper investigates how various emergent theoretical perspectives in entrepreneurship research, representing diverse decision-making logics, influence firm growth and evolution. It explores the interaction among decision-making logics, including experimentation, affordable loss, flexibility and pre-commitment as components of effectuation, alongside causation and bricolage and their synergistic effects on firm growth. Design/methodology/approach: This study uses a multi-phase, discovery-oriented approach. Initially, insights from existing literature on decision-making logic were combined with in-depth interviews with 10 Iranian entrepreneurs within the food sector. This phase used alternative template research to evaluate the principles of effectuation, causation and bricolage within case study data depicting firm growth. Subsequently, a self-administered survey was developed based on these insights and distributed to 205 entrepreneurs in Iran. The survey data was analysed using fuzzy-set qualitative comparative analysis (fsQCA) to identify key factors and pathways influencing firm growth. Findings: Using a discovery-oriented approach, this study formulates a comprehensive framework detailing decision-making logics that influence firm growth. Through fsQCA, 12 distinct paths are identified, highlighting the complex interplay of causation, effectuation and bricolage in high-growth firms within the food sector. Research limitations/implications: This study has limitations. FsQCA identifies only logically sufficient combinations, suggesting potential for exploring alternative pathways in future research. Given COVID-19's impact on the food sector, examining decision-making logic across diverse contexts and industries is advisable. Additionally, exploring how bricolage, causation and effectuation affect outcomes like new product development and innovation is essential in a growth-focused context. It is also important to consider environmental and organizational factors influencing growth. Originality/value: This paper pioneers the examination of emerging theoretical paradigms in entrepreneurship and their impact on firm growth. It identifies critical configurations of causation, effectuation and bricolage, providing actionable insights for navigating dynamic business environments. [ABSTRACT FROM AUTHOR]

While past research has shown that championing plays a key role in sheltering and advancing novel ideas towards implementation, relatively little is known about how adversity and failure are dealt with through championing behaviour. The current embedded case study draws from 43 interviews in a large industrial technology organization, examining new product and service development idea pathways. We found four types of championing responses in the 61 instances where initial idea advancement efforts did not bear fruit: lateral shifts, reworking, temporal shifts and moaning. In each of these, the idea was seen as valuable by the developer, but the attribution of initial failure and perceptions of effort‐to‐performance and performance‐to‐outcome expectancies varied in distinct combinations of conforming and nonconforming types of championing with varying intensity. Taken together, the results contribute towards understanding the multidimensional nature and temporal dynamics of championing in persisting under adversity by illuminating factors that contribute to championing response type decisions and opportunities to better support idea development efforts in organizations. [ABSTRACT FROM AUTHOR]

Our paper explores the integration of generative artificial intelligence (GenAI) into organizations' innovation and new product development processes, focusing on when and how to trust AI-generated outcomes in this context. We propose a framework to assess the level of trust required based on task-specific needs and the distinction between general and expert AI models. While inaccuracies in GenAI outputs can foster creativity during ideation, higher accuracy, and trust are essential for tasks requiring domain-specific expertise. The paper concludes by discussing the necessary human capabilities and organizational strategies for effectively deploying GenAI in innovation management. [ABSTRACT FROM AUTHOR]

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Product development durations are being drastically reduced, thanks, amongst other reasons, to the use of design automation techniques. But this trend is observed in large companies and to a much lesser extent in SMEs. This article seeks to research the possibility of finding suitable automation technologies for this type of enterprises. Automating the development of commercial offers in SMEs can be a good starting point to the change in this trend. Focusing on this objective, the necessary requirements that a tool of this type must have are established. Different models of assistants have been developed and analysed on different products, deducing from their results an ideal system architecture and methodology. This solution is based on design tables, a technology that links data from a spreadsheet, implements the company’s design process, with parameters of a three-dimensional CAD model, which represents the solution. The rest of the documents that constitute the commercial offer and the possibility of linking them with verification tools are derived from this design core. The main conclusion is the current viability of this method, anticipating the improvement of many aspects, mainly highlighting the link with the rest of the life cycle phases through interoperability tools. [ABSTRACT FROM AUTHOR]

The concept of sustainable development is driving shell biorefineries to develop a cost-effective and environmentally benign approach to transform chitin into high-value products. This study describes a green, simple, and flexible shell biorefinery process for producing two kinds of nanochitins (NCh), chitin solid residues (ChSRs) and chitin nanocrystals (ChNCs), by using p-toluenesulfonic acid-assisted hydrothermal treatment. The ChSR is a bundled nanocrystal with a long length ranging from 100 nm to 450 nm and a width ranging from 10 nm to 30 nm. It has an excellent interfacial behavior between the water and oil phases due to its amphiphilic nature; thus, a foodstuff-related emulsion has been successfully fabricated from soybean oil and a ChSR suspension without the addition of any synthetic surfactants. The further hydrolysed ChNC with a length and width range of 25–225 nm and 15–30 nm, respectively, and a high zeta potential of 41 mV exists as an individual nanocrystal. Owing to the abundance of positively charged groups distributed on its surface, ChNC enables self-assembly to a highly ordered hierarchical structure. Hence, ChNCs show promising results in fabricating large-area photonic films, e.g. for application in bright and vivid automobile painting. Altogether, we provide a novel approach to produce NCh materials from crustacean shell waste and bridge the gap from process engineering to high-value product development. [ABSTRACT FROM AUTHOR]

Plant-based protein foods are important products for sustainability, health, and ecosystem. Although vegans/vegetarians prefer these products, they have not received a widespread popularity due to significant differences in sensory properties and consumer experience compared to animal-based foods. Hence, sensory evaluation is the key in product development of these products. In this review, sensory techniques used for dairy, meat, egg, fish, and seafood analogs were analysed. Most studies involved affective and descriptive methods, and comparison of the sensory properties to see the gaps between plant-based and animal-based products. Parameters forming repetitive pattern in all studies are texture, appearance, aroma, flavor, and odor. Number of reported studies conducted on dairy and meat substitutes is higher than other categories. Egg analog sensory tests are developing especially with different applications like mayonnaise. However, there is a lack in fish and seafood substitute area. For now, the central issue in plant-based food development is to mimic flavor and textural properties. Therefore, there is a need in sensory research on these complex plant-based protein analogs with a range of different quality attributes to set the industrial standards, the research should be conducted in a variety of applications speeding up to launch alternatives for the interested consumers. [ABSTRACT FROM AUTHOR]

The core reason for the nutritional richness and special flavour composition of traditional Chinese fermented soybean products lies in the diversity of microbial structures and their metabolites, which include a variety of potential probiotics. However, relatively little mainstream research has been conducted on these microorganisms, especially in regions with unrelated product dietary habits, limiting the high-value utilisation of the characteristic microbial resources. In order to enhance the efficient use and functional exploitation of microbial resources in Chinese traditional fermented soybean products, this paper investigated and reviewed a variety of products such as soybean paste, soy sauce, douchi, sufu, and fermented soybean milk, and carried out a detailed analysis of the sources, flavour characteristics, and potential functionality of microorganisms therein, which elucidated that the microorganisms in Chinese traditional fermented soybean products have the potential to be used as functional probiotics, with a view to contributing to the probiotic resources exploitation, novel food development, and the development of new food products, as well as the development of new foods. [ABSTRACT FROM AUTHOR]