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The coffee paradox in stroke: Increased consumption linked with fewer strokes.
- Source :
-
Nutritional Neuroscience . Nov2016, Vol. 19 Issue 9, p406-413. 8p. 1 Diagram, 4 Charts. - Publication Year :
- 2016
-
Abstract
- Objective: To determine the association in amount of daily coffee consumption with incidence of stroke in a broad cohort, considering other vascular risk factors. Methods: We utilized the Third National Health and Nutrition Examination Survey (1988–1994; NHANES III) data on participants aged ≥17 years old to examine coffee consumption and stroke. Multivariate logistic regression models related the amount of coffee use reported in a food frequency questionnaire with stroke, controlling for other vascular risk factors. Results: Of 33 994 NHANES III subjects, coffee consumption and stroke data in adults ≥17 years old were available in 19 994. Daily coffee consumption ranged from 0 to 20 (median 1) cups and 644 (3.2%) participants had a stroke diagnosed by a physician. Coffee intake varied with age, gender, and ethnicity (P < 0.001). Interestingly, heart failure, diabetes, and hypertension were less frequent, and high cholesterol more frequent in those consuming ≥3 cups per day (P < 0.001). Smoking was more frequent in all coffee drinkers (P < 0.0001). Multivariate analyses revealed an independent effect of heavier coffee consumption (≥3 cups/day) on reduced stroke (OR 0.44, 95% CI 0.22–0.87,P < 0.02) in healthy subjects that was attenuated by vascular risk factors (OR 0.78, 95% CI 0.58–1.07,P ≈ 0.12). Conclusion: Heavier daily coffee consumption is associated with decreased stroke prevalence, despite smoking tendency in heavy coffee drinkers. [ABSTRACT FROM AUTHOR]
- Subjects :
- *STROKE
*COFFEE
*HEART failure
*DIABETES
*HYPERTENSION
Subjects
Details
- Language :
- English
- ISSN :
- 1028415X
- Volume :
- 19
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Nutritional Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 119356137
- Full Text :
- https://doi.org/10.1179/1476830515Y.0000000035