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Improving the Properties of L-Ascorbic Acid Biosensor Based on GO/IGZO/Al Using Magnetic Beads.

Authors :
Chou, Jung-Chuan
Wu, You-Xiang
Kuo, Po-Yu
Lai, Chih-Hsien
Nien, Yu-Hsun
Lin, Si-Hong
Yan, Siao-Jie
Wu, Cian-Yi
Liao, Yi-Hung
Source :
IEEE Transactions on Electron Devices. Apr2019, Vol. 66 Issue 4, p1924-1929. 6p.
Publication Year :
2019

Abstract

An L-ascorbic acid (L-AA) biosensor based on an indium–gallium–zinc oxide (IGZO)/aluminum (Al) membrane modified by graphene oxide (GO) and magnetic beads (MBs) was produced and trusted to investigate its potential biosensor applications. An atomic force microscope, scanning electron microscope (SEM), and electrochemical impedance spectroscopy (EIS) were used to analyze electron transfer resistance (${R} _{\textsf {et}}$), surface roughness, and surface morphology. The experimental results show that the L-AA biosensor possessed the average sensitivity of 78.9 mV/decade with a linearity of 0.997. The experimental results from the EIS confirm that ${R} _{\textsf {et}}$ can be improved by the addition of GO and MBs. This paper opens a new window for the detection of L-AA based on MBs-ascorbate oxidase/GO/IGZO/Al sensing membranes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00189383
Volume :
66
Issue :
4
Database :
Academic Search Index
Journal :
IEEE Transactions on Electron Devices
Publication Type :
Academic Journal
Accession number :
136509861
Full Text :
https://doi.org/10.1109/TED.2019.2901053