Development of online sampling and matrix reduction technique coupled liquid chromatography/ion trap mass spectrometry for determination maduramicin in chicken meat.

Highlights: [•] An online sample pretreatment technique coupled LC/MS/MS was developed. [•] A matrix-matched internal standard calibration method was used for maduramicin residue determination in chicken meat. [•] An ion enhancement effect was found for maduramicin detection. [•] Maduramicin residues in incurred chickens decrease during the withdrawal period. [ABSTRACT FROM AUTHOR]